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Query: gi|238922433|ref|YP_002935946.1| chromosomal replication initiation protein (EUBREC_0001) [Eubacterium rectale ATCC 33656], from E.rectale

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDKVMEKWNEILQMVKEEHGLTDVSFNTWIKPLEVFAIDGNTLYILVPSEQMGLSYINKKYYLPLKVAIGEVTGIEYDIQFILPDQAQSLKFKNNDTPQLEQQTPVKGDHSNLNPNYTFDTFVVGNNNRFAHSASLAVAESPGEAYNPLYIYGGPGLGKTHLMHSIGHFIIDQNPDTKVLYVTSEEFTNEVIESIRNGNSSAMTKFRDKYRTVDVLMIDDIQFIIGKESTQEEFFHTFNTLQTQGKQIILTSDKPPKEMETLEERIRSRFEWGLMADIGTPDYETRMAILRKKAETDNFDIDDDILNYIASNISSNIRELEGALNKLLAFHNLEHTHITMDIAERELSNIITPDKPREITAQLIIEVVSEHFHISVDQMISKTRSSEIARPRQIAMYLCKTMTSDSLDVIGQLLGGRDHSTIIHGIKKVTKDYEENDSTRTLIETIKKKINPNLast
1 -118.000[L] COG0593 ATPase involved in DNA replication initiation  ali follow..  33  2..NLSNLWQSCLLQLQDQ--VSASDLSTWLRPLQADVVADNHIVLYASNM-FVKGWVETHYLAQIQQICQTLAQNPELRISLKEGVKPAPKIVESTPNTQAESSASVKFESHLNTKHLFDNFVEGKSNQLARAVGQKLAQAPGESANPFFLYGGTGLGKTHLLHAIGNGILADKPNARVLYIHANNFMQHMVKAVRDNK---MDQFKKFYRSLDALLVDDIQFFAEKEKTQEEFFHIFNSLFETGRQIILTSDRYPKEIEKIEERLKSRFGWGLTTAIEPPDLETRVAILLKKAEEHNMNLPEEVAFFIAQRLRTNVRELEGALNRVKAMQDFKGGDIDIDFVRDTLKDILA-LQERLVTIENIQKVVAEYYRIKVSDLKSKSRARSVTRPRQIAMALAKELTNRSLPEIGRAFD-RDHTTVLNACREVPKFREQDNSIQEDWANLIRTLSA. 454
2 -22.800[L] COG1484 DNA replication protein  ali follow..  16  80...................................................................................................................QLGFKEFRTEGKPQCTKEYVADYEQIKDCRKNSIALLGQPGSGKTHLLTAAANELMRTC-YVPVIYFPFVEGFTDL-----KNDFALLEAKLNRMKQADVLFIDDL---RATDWQLEQMYSVLNYRYLNHKPILLSSELTIEGLVRVDEALGTKI--DYLVIIKGAAYELNHRLEGVR................................................................................................................................................................ 266
3 -14.500[L] COG2255 Holliday junction resolvasome, helicase subunit  ali follow..  12  3............................................................................................EADRLISAAVINDEESIDRAIRPK-LLTEYV-GQPHVREQEIFIQAAKQRGDALDHVLIFGPPGLGKTTLANIIANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPH---------------DVLFIDEIHRL--SPVVEEILY----PAMEDYQLDIMIGEGPAARSIKLDSPLRDRFG--IVQRLEFYQVADLEHIVSRSAKCLGLELTPEGAHQLARRSRGTPRITNRLLRRVRDFAEVRADGAINGEVAMKALDMLNVDAEGFDFMDRKLDNLAAAIGEERETIEDVLEPYLIQQGFIQRTPRGRIATNHAYKHFG.......................................... 329
4 -12.600[L] KOG0990 Replication factor C, subunit RFC5  ali follow..  13  13....................................................................................DEIQPRKPINKGKDVVGFGPPPQSKATPWVEKYRPQSLVAAH-RDIIDTIDRLTNEN---KLPHLLLYGPPGTGKTSTILAVARKLYGPKYRNMILELNASD--DRGIDVVRQQDFASTQSFSLGKSSVKLVLLDEADAMT--KDAQFALRRVIEK-YTKSTRFALIGNHVNKIIPALQSRC-TRF------RFAPLDGVHMSQRLKHVIEAERLVVSDCGLAALVRLSNGDMRKALNILQSTHMASKEITEEESKQITEEDVYLCTGNPLPKDI--EQISHWLLNKPFDECYKDVSEIKTRKGLAIVDIVKEITLFIFKIKMPSAVR-------VQLINDLADIEYRLSFGCNDKLQLGAIISTFTH. 359
5 -12.400[R] COG2607 Predicted ATPase (AAA+ superfamily)  ali follow..  14  60..........................................................................................................................LAGVGRQTELLVRNTEQFIVGRPANNVLMSGARGTGKSSLVKALLHEY--ADKGLRLIEVDKSDLIGYLLTLLKECPEK-------------IVFCDDLSFESGDETANVLVYATSNRRHENAGTTGMRGEIHQKEAVEEKISLSDRF--GLWLSFYPFDQNDYLAAVQNWLEDFGVPYDETALQWAQTRGSRSGRSAWQFACDWAGRLPKQRA..................................................................................................................... 286
6 -12.200[L] KOG2028 ATPase related to the helicase subunit of the Holliday junction resolvase  ali follow..  14  78...................................................................................QIHVAADDSNKRHKLSSSSHRQHQPLSERMRPR-TLDDVV-GQDHLLSPSSLLRSAVESNRLPS-IVFWGPPGTGKTSIAKSLINSSKDPSLYRFVSLSAVTSGVKDVRDAVESAKRL-----NLEGRKRTVLFMDEVHRF---NKSQQDTF--LPVIEDGSILFIGATTENPS---HLITPLLSRCRVLTLNPLKPNHVETRAVDDSERGLPNSVEVDDSVIEFLANNCDGDARVALNALEISATMAT-TDAVVSIDDAKEALQ-------CKHLAYDKAGEQHYNLISALHKSMRGGDANAAIYWLARMPLYIARRLIRFASEDIGHFLGMPECNVILAQCTAYLALAPKSIAVYRAIGAAQKVVKDS 454
7 -11.800[DL] KOG2035 Replication factor C, subunit RFC3  ali follow..  10  7...................................................................................................................KYRPKDLLGKDGVDYHIEQANHLKFLSADCMPHLLFCGPSGAGKKTRIKCLLRELVSSNYHIEMTPSDVGIYDRVVVQDLVKEMAQTSQIESTSQRSFKVVVLCEADSLT--RDAQHGLRRTMEK-YANNCKIVLSCESLSRIIEPLQSRC-------IIINVPAPTDEDVTKVLRKVIERESFLLPENVLQKIVEKSEGNLRR---AILMTEALRMENESGVAESVVIPVPEWEIYIQETARLILQKQSSDMLLKVRERLYELLSRCIPPTVIF-KKLLEHLLPKCPPQIAREVVSEAAKFEH--------RLVLGQKAIFHLEGFVAAFMDIYLTN 349
8 -11.700[R] COG1223 Predicted ATPase (AAA+ superfamily)  ali follow..  16  88......................................................................................................ESDPRVIETEIVRDITLDDVVGQEEAKRKAKVILEYLRNPKWAPKNVLFYGPPGTGKTMMAKALSNEA-----KTPFLSVKSTKLIGEHVGDGARRVHELYERARQL-----IVFLDEFDAIALDSEIVNALLTELDGTNSNEGICTIAATNRVE----LDASIRSRFEEEIEFRL--PSYEERLEILRRNLEEFPVPVKARLELVAAASEGFSGRDLVEKVIKLHKAIAEGKDKIETEDLLTAAEKVKMPSRQPPKQMF........................................................................................... 351
9 -11.600[L] COG0470 ATPase involved in DNA replication  ali follow..  13  49....................................................................................................................................................LLFYGPPGTGKTSTIVALAREIYGKNYSNMVLELNASD--DRGIDVVRNQIKDFASTRQIFSKGFKLIILDEADAMT--NAAQNALRRVIER-YTKNTRFCVLANYAHKLTPALLSRC-TRF------RFQPLPQEAIERRIANVLVHEKLKLSPNAEKALIELSNGDMRR---VLNVLQSCKATLDNPDEDEISDDVIYECCGAPRPSDL--KAVLKSILEDDWGTAHYTLNKVRSAKGLALIDLIEGIVKILEDYELQNEETR------VHLLTKLADIEYSISKGGNDQIQGSAVIGAIK.. 328
10 -11.500[O] KOG0728 26S proteasome regulatory complex, ATPase RPT6  ali follow..  15  185....................................................................................................................................................VLLYGPPGTGKTLLARAVAHHT-----ECTFIRVSGSELVQKFIGEGSRMVRELFVMARE--HAPSIIFMDEIDSIGSSQRTMLELLNQLDGFEATKNIKVIMATNRIDILDPALLR--GRID----IEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYARERRVHVTQEDFEMAVAKVMQKDSEKNM.............................................................................................. 398
11 -11.500[O] COG1222 ATP-dependent 26S proteasome regulatory subunit  ali follow..  15  185....................................................................................................................................................VLMYGPPGTGKTLMARACASKT-----NATFLKLAGPQLVQMYIGDGARLVRDAFALAKE--RKPTIIFIDEIDAIGAKQRTMLELLNQLDGFSSSEEVKIIAATNRVDILDPALLR--GRLD----IEFPLPNTLGRKRILQIHARKMSVRDDVNFDELARSTEGFNGAQCKAVCVEAGMAARKEKTEISQNDFMDGIQEVLSRKKSKLL.............................................................................................. 398
12 -11.500[LD] KOG2227 Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase  ali follow..  11  126..........................................................................................................................ILCREDEQIRIFEFVKGCIDQQKAGSLYICGCPGTGKSLSMEKVVQQVGDWSPPVDTLSVNCTSLSKKILGEIKPGKNANSQKQESSSSRMMLIIADEMDYLITKD--RGVLYDLFMLTTLPFSRCILIGVANAIDLADFLPKLKSLNCKPMVITFRAYSKDQILRILQERLRVLSYVFQPKALELCARKVAAASGDMRKALCVCRSALEILEIETRGSTGPE---SQGPTPDDSVVRMDHMAAALSKTFKSPVVETI-----QSLPQHQQIIICAAAKAFRGSKKDA---------GELNKLYLEICKSWMISPAGITEFTNMCTVLND. 464
13 -11.400[LO] COG1474 Cdc6-related protein, AAA superfamily ATPase  ali follow..  14  28...........................................................................................................KNKEVLRPSYTPDL-LLHRNEQINSLATILVSALRGETPSNVLIYGKTGTGKTYVGKELERVSEDKSLFCSVVYINCEVIDTNLARHFEEEVPMTGWPTDQVFMKF-IIILDEIDKLIKKGDDVLYNLSRINTDLRKAKVSMIGVSNDLKFTEFLDPRVKSSLGEEELI-FPPYDAEQISDILKQRAKMA--VLGEMVIPLCAAFAAQEHGDARRALDLL-----------------RVSGEIAERENQPQVLEEHVRRAQEKIEIDRVVEVV-----RTLPTQSKLVLYSIILLRSRGREGKNVTTG-----EMYNVYRQLCHHIDVDILTQRRVTDLMSELDM. 365
14 -11.400[O] KOG0741 AAA+-type ATPase  ali follow..  15  256....................................................................................................................................................ILLYGPPGCGKTLLARQIGKMLNARE----PKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLHIIIFDEIDAICKQDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLI---DEALLRPGRLEVKMEIGLPDEKGRLQILHARMRGHQLLSADVDIKELAVETKNFSAELEGLVRAAQSTAKAESLQVTRGDFLASLENDIKPAFGTNQEWGDPVTRVLDDGELLVQQLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMIGFSETAKCQAMKKIFDDAYKSQLSCVVVDDIERLLDYVPIG 615
15 -11.300[O] KOG0739 AAA+-type ATPase  ali follow..  16  163....................................................................................................................................................ILLFGPPGTGKSYLAKAVATEA----NNSTFFSVSSSDLMSKWLGESEKLVKNLFE---ARQHKPSIIFIDEVDSLCGSRNENEEFLVQMQGVGNNNDGTVLGATNIPWV---LDSAIRRRFEKRIYIPL--PEEAARAQMFRLHLGSTPHNLTDANIHELA-------RKTEG-------YSGADISIIVRDSLMQPVRKVQSATHFKKVC............................................................................................. 359
16 -11.000[H] COG1239 Mg-chelatase subunit ChlI  ali follow..  10  58..........................................................................................................................VVGYDDTVIPQLVNALLARQN-----FILLGLRGQAKSRILRAITELLLPRADRYVEKLATPDVTVADLIGDVDPIKAARLGTSLGDTRSMGIFAVNELADLSPKNILQEGDVQIKGYPIRLELDVMLVFSANPEDYTAIVTPLKDRI--GSEIRTHYPDVQLGMDITAQEAVEEGVVVPPFIAELIED-IAFQAREDGRIDKLSGVSQRLPISLMELACANAERRSLVSGDAPVVRVTDVYAGLPA---------ITGKMELEYEGELKGADNVAKDLIRKAAGAAYARSYGSADTRELEKWFDQGNVFRFPQGGDASAALKATGEVPG. 430
17 -10.900[O] KOG0727 26S proteasome regulatory complex, ATPase RPT3  ali follow..  11  192....................................................................................................................................................VLLYGPPGTGKTMLAKAVANHT-----TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKE--NAPAIIFIDEVDAIATAQRILMELLNQMDGFDQTVNVKVIMATNRADTLDPALLR--GRLD----IEFPLPDRRQKRLVFQVCTSKMNLSDEVDLEDYVSRPDKISAAEIAAICQEAGMHARKNRYVILPKDFEKGYRANVKKPDTD................................................................................................ 403
18 -10.900[O] KOG0733 Nuclear AAA ATPase (VCP subfamily)  ali follow..  13  529....................................................................................................................................................VLLWGPPGCGKTLLAKAVANES-----KANFISIRGPELLNKYVGESERAVRQVFLRARA--SSPCVIFFDELDAMVPRRDDSLTLLTELDGLSDRSGVYVIAATNRPDIIDPAMLR--GRLD----LLVDLPDAHERVEILKTLTKQTPLHEEVNLDVLGRDERCSNFADLA-ALVREAAVTALRSAVFADIASNEPEITQHSALEPIRVTNADFELAFKNI-SVSDRDRQKYQRLAK.................................................................. 768
19 -10.800[L] KOG0991 Replication factor C, subunit RFC2  ali follow..  14  10....................................................................................AGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLIVGN-EDTVSRLEVFAREG---NVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELSNDRGIDVVRNKIKMFAQQKVTLPKGRHK---IIILDEADSMT--DGAQQALRRTMEI-YSKTTRFALACNASDKIIEPIQSRCA-------VLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFG-------------------------FINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHL.................................................... 288
20 -10.700[O] KOG0652 26S proteasome regulatory complex, ATPase RPT5  ali follow..  14  208....................................................................................................................................................VLLYGPPGTGKTLMARACAAQT-----NATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKE--KAPCIIFIDEIDAIGTKQRTMLELLNQLDGFSSDERIKVIAATNRADILDPALMR--GRLD----IEFPHPTEEARARILQIHSRKMNVHPDVNFEELARSTDDFNGAQLKAVCVEAGMLARRDATEVNHEDFNEGIIQVQAKKKAS................................................................................................ 419
21 -10.700[S] COG4916 Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain  ali follow..  11  9.......................................................................................................................DVFKTVGLPPYTYVKPKHFGEVRADISQVLLIEGPSGIGKTCVVFKVFEELQWSQGRDFTYVGCRDQNAEQIIDDFLKNAAAGNALSPC------VLVIDDFHLL--SQAKRMEIGSTLKRLSDRAKVILIGIPTAGVSLLSDAYDLGPRLG---SYALTRASDVEIDKLISEGEQALAVLF--EDRDVLLAESAGNFWLAQYVCNKVCAIEEVYETQDDAKILTFDILGIR----------GRLMAELTQRYLPIARTFAKGKRWRP.................................................................. 263
22 -10.700[O] KOG0726 26S proteasome regulatory complex, ATPase RPT2  ali follow..  13  221....................................................................................................................................................VILYGPPGTGKTLLAKAVANQT-----SATFLRVVGSELIQKYLGDGPKLVRELFRVAEE--HAPSIVFIDEIDAVGTKQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIR--GRID----IEFPLPDEKTKRRIFTIHTSRMTLAEDVNLSELIMAKDDLSGADIKAICTEAGLMARERRMKVTNEDFKKSKESVLYRKKEGTPE............................................................................................. 435
23 -10.700[O] KOG0737 AAA+-type ATPase  ali follow..  16  451....................................................................................................................................................ILLFGPPGTGKTMMAKAIANEA-----GASFINVSMSTITSKWFGE-DEKNVRALFTLAAKVSPT-IIFVDEVDSMLGQRKIKNEFMTHWDGLMSNAGDLVLAATNRPFDL---DEAIIRRFERRIMVGL--PSVESREKILRTLLSKEKTE--QELAQMTDGYSGSDLKNFTAAYRPVRELIKQECLKDQERRKREEAEK--NSEEGSEAKEEVSEERGITLRPLSMEDMKVAKSQVAASFAAEGA.......................................................... 699
24 -10.600[O] KOG0651 26S proteasome regulatory complex, ATPase RPT4  ali follow..  16  187....................................................................................................................................................CLLFGPPGTGKTLLARAVASQL-----DCNFLKVVSSAIVDKYIGESARMIREMFNYARD--HQPCIVFMDEIDAIGGRQRTLMELLNQLDGFDSLGKVKVIMATNRPDTLDPALLR--GRLD----IEIGLPNEQSRLEILKIHSNKITKHGEIDFEAVVKLSDGFSAADLRNVCTEAGMFARAEREFVIDEDFMKAVRKVGDAKRLE................................................................................................ 398
25 -10.600[L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase  ali follow..  12  25.....................................................................................................................TVEQYI-GQQHILGPGKPLRRALEAGHIHS-MILWGPPGTGKTTLAEVAANYA-----NAEVERVSAVTSGVKEIRAAIEKARENKLSGRRT-----ILFVDEVHRF---NKSQQDAF--LPHIEDGTVTFIGATTENPS---ELNNALLSRARVYKLTSLNQQEILQALHQAIADTEKVAAVFADNVLDRLAELVNGDARMSLNYLELLYDMAR-GRKQIDLPLLAEVAG-------EKVSRFDNKGDIWYDLISAVHKSIRGSDPDAALYWAARMILYIARRLLAIASEDVG.......................................... 305
26 -10.400[O] KOG0730 AAA+-type ATPase  ali follow..  13  550....................................................................................................................................................VLFYGPPGCGKTLLAKAIANEC-----QANFISVKGPELLTMWFGESEANVREIFDKARQ--SAPCVLFFDELDSIATQRGNSAQLLTEMDGMNAKKTVFIIGATNRPDII---DSALLRPGRLDQLIYIPLPDEDSRLNIFKACLRKSPVALAKYTQGFSGADITEICQRAC-AIRENIEKDIENERRRSQNPEAMEEDM--VDDEVSEIRAAHFEESMKYA-SVSDADIRKYQAFAQRGFGSEFRFDVGRTTGVAAADPFATSA....................................... 833
27 -10.400[L] COG2812 DNA polymerase III, gamma/tau subunits  ali follow..  13  6................................................................................................................LYRVWRPQKLVVGQEH----TKTLQNALVQEKFSHAYLFSGPRGTGKTSAAKIIAKAIKGITSGSIVDVMEIDAASNNGVDEIRDRDHVKFAPSEVRYK---VYIIDEVHMLTTG---------AFNAL-------LKTLEEPPSHAHKIPLTIISRCQ-----DFKRISNDALVGRMKEILTHEGIEAEDEALVLVARAAEGGMRDSLSLLDQAISFA---DERVTVEDVLAITESAQKGETAEALQLVNQLLANGKDPLRFVEDLIYYYRDLMLFAAPEASQLLERAQINDSFKTLAGEINDASLFAAIEILNDCQQRMRWSSHPRVALELGVVTL... 357
28 -10.100[R] COG1485 Predicted ATPase  ali follow..  12  75....................................................................................................................................................LYFYGGVGRGKSFLMDAFFGCL-PYRRKRRVHFHAFMAEIHQRLKTLKSESNPLKSVAAEIAKETRVLCFDEFHVSDIADAM---LGRLLENLLNEGVVLVATSNYAPSEL----------YPQGQNRSSFLP-----IALIESSLTVLNVDGGEDY-IFFTPANEENEAKLAKLFKEMTGITDLNPGISTIAESGRAIWFDFRALCFGPRSQSDYLYLAEHYEMVFISGLEQLSPQEKAEARRLTWLI-VKLCATGAVDVNHIYTEGDFAEEFTRTASRMVEMQSEV................. 367
29 -9.940[O] COG0465 ATP-dependent Zn proteases  ali follow..  16  146.................................................................................................................QIKTSFAD-VAG-----CDEAKEEVSELVDYLREPVLMVGPPGTGKTLLAKAIAGEA-----KVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKA-----IIFIDEIDAVGRQEQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLR--GRFDRQVVVGL--PDVRGREQILKVHMRRVPLDTDIDASVIARGTPGFSGADLANLVNEAALFAARGNKRVSMVEFEKAKDKIMMGAERRSMVMTEAQKESTAYHEAGHAII-HDPVHKVTIIPRGRALGVTFFLPEGDESQISTLYGGRLAEEIIYGPEKVSTGASNDIKVATSI.......... 499
30 -9.930[L] KOG1514 Origin recognition complex, subunit 1, and related proteins  ali follow..  11  359....................................................................................GLEKVGMKRIPEHVRCHKQSELEKAKATLLLATRPKS-LPCRSKEMEEITAKGSISDDQCLGRCMYIHGVPGTGKTISVLSVMKNLKAE-SPYCFVEINGLKLASVIYEGLSGHRVAEGKKIGKENEKPCILLIDELDVLVTRN--QSVLYNILDWPTKPNSKLVVLG----ANTMDLPEKLLPRISSRMRLCFGPYNHRQLQEIISTRLEGINA-FEKTAIEFASRKVAAISGDARRALEIC-----------AAEVADYRLKKSNISAKSQLVIMADVEVAIQEMFQAPHIQMKSVSKLSRIFLTAMVHELYKTGMAETSFDRVATTVHRLQKLQLNFPSDDVAFALKDNKDLPWLANYL....... 771
31 -9.890[R] KOG2383 Predicted ATPase  ali follow..  17  132....................................................................................................................................................LYVYGDVGTGKTMVMDMFYAYV-EMKRKKRVHF---HGFMLDVHKRIHRLKQSLPKR-EEISEEACLLCFDEFQVTDIADAM---LKQLFENLFKNGVVVVATSNRPPEDL----------YKNGLQRANFVP-----IAVLKEYCNTVQLDSGID-KLYYLTSEADVEAVMDKLFDELAQKQNDLTRPRILKVQGRELRLNKACGTVADCTFEELLELSKNFDTIFLRNIPQFTLANRTQGRRFITL......................................................... 393
32 -9.820[O] KOG0729 26S proteasome regulatory complex, ATPase RPT1  ali follow..  15  212....................................................................................................................................................VLLFGPPGTGKTLCARAVANRT-----DACFIRVIGSELVQKYVGEGARMVRELFEMART--KKACLIFFDEIDAIGGAQRTMLELINQLDGFDPRGNIKVLMATNRP---DTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFARARRKIATEKDFLEAVNKVIKSYAKFSATPRYM......................................................................................... 430
33 -9.820[L] KOG2228 Origin recognition complex, subunit 4  ali follow..  12  560...............................................................................................................................TKLYQWVRQTIVLGEG---NSVIIVGPRGSGKSVLVDILSRAAQEINEKSYVVRLNGTYQTDDLLATLSHPVDLGIAEDVMTTSAAVIFVLEEFDLFVQHSR-QMLLYNLFDIAQSRKAPILIIGLTTRYDCSELEKRVKSRFSHMVIPMRPPSSLSEFEQILKSVLYVSDEGGKDQIITCWNQRVDELLSDTRSHLHKLVQHHYFASRNLK-LLYVDLLFPILSMAPDRPLLADEDFANISLKVSDHKVELVKNLSLLELALLICAVRFEARDIPACNFNSAYQEY....................................... 879
34 -9.790[O] COG0464 ATPases of the AAA+ class  ali follow..  10  253....................................................................................................................................................VLLQGPPGTGKTMLAKAVANES-----DAYFISINGPEIMSKYYGESERAIREIFEDAEK--NAPAIIFLDEIDSIAPKRRVVAQLLSLMDGLKARKNVIVIGATNRPEAL---DIALRRPGRFDREIELRVPDTEGRLEIFQIHTRGMPLADNVNLMDFAQITYGFVGADIAALCREAAMSAILDALQVTREDFENALKDVQPSAIREILILERVKELLKEVVEWPLKNLYGPPGTGKTLLAKAIAHESDANFITAKGSDLLSKWYGESEKRIAEVFTRARQVAPS---FLDELDSLAPIRGTS 601
35 -9.460[O] KOG0740 AAA+-type ATPase  ali follow..  15  395.................................................................................................................GPPVNWED-IAG---EFAKATIKEIVVWP--MLRPILLFGPPGTGKTLIGKCIASQS-----GATFFSISASSLTSKWVG---EGEKMVRALFAARCQQPAVIFIDEIDSLLSQRGDGEEFLVQLDGATTSSEDLVVGATNRPQEI---DEAARRRLVKRLYIPL--PEASARKQIVINLMSKEQCCLSEEEIEQIVQQS-------DA-------FSGADMTQLCRGASLGPIRSLQTAD--ATITPDQVRPIAYIDFENAFRTVRPSVSPKDLE----------------LYENWNKTFGC..................................... 672
36 -9.430[R] KOG2170 ATPase of the AAA+ superfamily  ali follow..  8  70...................................................................................................................DADIANLLFGQHDVVVNSIKSHWYNENPRKPLVLSFHGYTGSGKNYVAEIIANNTFRLGLRSTFVQHIVATNDFPDKNKLEEYQVELRNRILTTVQKCSIFIFDEA------DKLPEQLLGAIKPFLDYYSTFILLSNKGGGEIARITKEQYESGYPREQLRLEAFERELMNFSYNEKGGLQMSEL-NHLIDHFVPFLPLQREHVRSCVGAYLRKRGRGDLVSNVDFVERVLNSLQYFPESSKAFSSSGCKRVDAKTDLEMAKIRPLLSSVH.................................................................. 351
37 -9.130[R] COG0714 MoxR-like ATPases  ali follow..  13  11.....................................................................................................................NLSQTIVGKDEAIRLVLVALLSGG-------ALLEDVPGVGKTLLAKSLARSI---NGKFQRVQCTPDLLPTDITGTNIWNPSSREFEFLPGPAFANILLADEINRATPREVMEEKQVTVDGETRLVPHPFFVIATQNPIEYQGLPEAQLDRFALSLSLGYPSEAEELKMEVEALQKAVRQVKLTEDLQQYLLRLVRAS-RTDEDVTLGVSPRGTTALQRATQAFAFLEERDYAIDDDVKFVAPHVLAHRLIPASGKDPKAILQR....................................................................... 296
38 -9.070[QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism  ali follow..  14  311....................................................................................................PHSKVRAPLVSREQIPPALRR-LGGDAPVI--AALQAKAAKLARTRLPILIQGETGTGKEHLARAIHEGSGLEGPFVAI-LIESELF-GAFTGASAKGRKGLIEQ-----ADGGTLFLDEIGDMP---ALQSRLLRVLAE-RKVRIRIVSASHRPLQTLGAFREDLYYRLN---AATLTLPALRDRPDFLLKRHGDGELILSPAALSALKAH-PGNIRELDNVIGVAAALAEVELGDLPDQLLANADTVGGNEASATLSLT---ISEAARRLGLDRSTVHRQIKRYRLKPHRH............................................................ 627
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Alonso A, Sasin J, Bottini N, Friedberg I, Friedberg I, Osterman A, Godzik A., Hunter T, Dixon J, Mustelin T. Protein tyrosine phosphatases in the human genome. Cell. 2004 Jun 11;117(6):699-711. Review.