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Query: gi|238922446|ref|YP_002935959.1| chaperone protein DnaK (EUBREC_0020) [Eubacterium rectale ATCC 33656], from E.rectale

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGKVIGIDLGTTNSCVAVLENNQPVVITNSEGQRTTPSVVAFTKNGERLVGEAAKRQAAVNVDRTFFSIKRQMGSDFRAKVDGKLYSAPEISSMILRKLKKDAEDYIGEAVTDAVITVPAYFSDAQRQATKDAGRIAGLNVLRIINEPTSAALAYGLDHGQQQKILVYDLGGGTFDVSVIEIGDNLIEVLATAGDNHLGGDDFDERITNYLVTEFYRQQNVDLRKDNTAMQRVREEAEKAKKVLSSSSSTTINLPFITTVKGQPVHMEMNLTRAEFNEITKDLVERTAIPVNQALSDAGISAAELGMVLLVGGSTRVPAVVEEVRRITGKEPSHNLNPDECVALGAAVQGGKLGGAIVAGSSAAEIILMDVTPLSLGIETVGGVSTKIIDRNTTIPTRYSQIFTTAGSFQTSVDIKVLQGERQFARDNKLIGNFRLKGIKPAPAGVPQIEVTFDIDANGIVQVSAKDLGTGKHQEITITASSNLSDSEIEQAIREAQEYEATDGQRKAYIDARSEADTLVRQVENVMADKEKRKAMDSAQKKSVKSSLSYVKKLISRTKPGNVSEEQAAEIKHAADELRNAAAGLILast
1 -154.000[O] COG0443 Molecular chaperone  ali follow..  54  1MAKILGIDLGTTNSCMAVMEGGDAVVLPNAEGSRTTPSVVGFSKKGEKLVGQVAKRQAISNPENTVYSIKRHMGEANKVTLNGKTYTPQEISAMILQKLKTEAEAYLGETIKQAVITVPAYFNDAQRQATKDAGSIAGLEVLRIINEPTAASLAYGLDKGVDQKILVYDLGGGTFDVSILELGGGVFEVKSTSGDTHLGGDDFDQRVIDHLLAEFKKTEGIDLSKDKAILQRLKDAAEKAKIELSGVTVTNINLPFLTVGDGEPKHMDIDLTRAQFQKMTEDLLEKTLVSMRRALSDSKLTPNDLDKVILVGGATRMPAVVELVENFTGKKPYKNINPDEAVAIGAAIQAGVLGGE------VKDVLLLDVTPLTLGIETLGGIATPLIQRNTTIPTKKSQIFSTAADNQPSVEIHVLQGERGIASENKTLGRFTLDGIPPAPRGIPQIEVAFDIDANGILHVNAKDLGTGKEQSISIQKPGGLSDAEIERMVKDAELHAEEDKKRKEEVETRNNAEALINAAEKTIKEA--GDVATEDQKSKVNAAIEDLKKALEGKD--------TEEVKAKTEALQEAVYPI. 572
2 -152.000[O] KOG0101 Molecular chaperones HSP70/HSC70, HSP70 superfamily  ali follow..  46  4.AAAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFT-DTERLIGDAAKNQVALNPQNTVFDAKRLIGRKFGDKGETKAFYPEEISSMVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDRTGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLF----EGIDFYTSITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFGRDLNKSINPDEAVAYGAAVQAAILMGD--KSENVQDLLLLDVAPLSLGLETAGGVMTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIEVTFDIDANGILNVTATDKSTGKASKITITNDKRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKKKVLDKCQEVISWLDANT-----LAEKDEFEHKRKELEQVCNPII 607
3 -151.000[O] KOG0100 Molecular chaperones GRP78/BiP/KAR2, HSP70 superfamily  ali follow..  47  34LGSVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVGFT-DSERLIGEAAKNQAAVNPERTVFDVKRLIGRKFEDDGETKVFSPEEISAMILTKMKETAEAYLGKKIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGEKNILVFDLGGGTFDVSVLTIDNGVFEVLSTNGDTHLGGEDFDHRIMEYFIKLIKKKHQKDISKDNKALGKLRRECERAKRALSSQHQVRVEIESLF----DGVDLSEPLTRARFEELNNDLFRKTMGPVKKAMDDAGLQKSQIDEIVLVGGSTRIPKVQQLLKDFFGKEPNKGVNPDEAVAYGAAVQGGILSGE--GGDETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLTKDCRLLGKFDLTGVPPAPRGTPQIEVTFEVDANGILNVKAEDKASGKSEKITITNEKRLSQEEIDRMVKEAEEFAEEDKKVKEKIDARNALETYVYNMKNQVSDKDLADKLEGDEKEKIEAATKEALEWLDENQ-----NSEKEEYDEKLKEVEAVCNPII 639
4 -146.000[O] KOG0102 Molecular chaperones mortalin/PBP74/GRP75, HSP70 superfamily  ali follow..  49  50.GPVIGIDLGTTTSCLAIMEGQTPKVIANAEGTRTTPSVVAFTKDGERLVGVSAKRQAVINPENTFFATKRLIGRRFKLEARGKTYSPSQIGGFILSKMRETASTYLGKDVKNAVVTVPAYFNDSQRQATKAAGAIAGLNVLRVVNEPTAAALAYGLDKKNDAIVAVFDLGGGTFDISILELNNGVFEVRSTNGDTHLGGEDFDVALVRHIVETFKKNEGLDLSKDRLAVQRIREAAEKAKCELSSLSKTDISLPFITADATGPKHINMEISRAQFEKLVDPLVRRTIDPCKRALKDANLQTSEINEVILVGGMTRMPRVVETVKSIFKREPAKSVNPDEAVAIGAAIQGGVLSGH------VKDLVLLDVTPLSLGIETLGGVFTRLINRNTTIPTRKSQVFSTAADGQTAVEIRVFQGERELVRDNKLIGNFQLTGIAPAPKGQPQIEVSFDVDADGIINVSARDKATNKDSSITVAGSSGLTDSEIEAMVADAEKYRASDMARKEAIENGNRAESVCTDIESNLDIDKLDQQAVEDLRSKITDLRETVAKVNAGDE-----GITSEDMKKKIDEIQQLSLKVF 649
5 -94.200[O] KOG0103 Molecular chaperones HSP105/HSP110/SSE1, HSP70 superfamily  ali follow..  26  2..SVVGFDFGNENCLVAVARQRGIDVVLNDESNRETPAIVCFG-DKQRFIGTAGAASTMMNPKNSISQIKRLIGRQFSDPEEKRAFTPTQVMGMMLSNLKGIAEKNLNTAVVDCCIGIPVYFTDLQRRAVLDAATIAGLHPLRLIHETTATALAYGIYKTDQLNVAFIDIGHASMQVCIAGFKKGQLKILSHAFDRSLGGRDFDEVLFNHFAAKFKDEYKIDVSQNAKASLRLRATCEKLKKVLSANPLAPLNIECLM----DEKDVRGVIKREEFEEISIPILERVKRPLEKALSDAGLTVEDVHMVEVIGSGSRVPAMIKILTEFFGKEPRRTMNASECVSRGCALQCAILSPT-----KVREFQVHESFPFSISLAWKGQQSTIVFPKGNPIPSVKALTFYRSGTFS----VDVQYSDVNDLQAPPKISTYTIGPFQSSKGERAKLKVKVRLNLHGIVSVESATLLEEEEVEVPVTKEHSLKTVEVEKAVEKEFEMALQDRVMEETKDRKNAVESYVYDMRNKLSD-KYQEYITDSEREAFLANLQEVEDWLYEDG----EDETKGVYVAKLEELKKVGDPVE 691
6 -84.500[O] KOG0104 Molecular chaperones GRP170/SIL1, HSP70 superfamily  ali follow..  24  24.LAAMTIDLGTQFLKIGIVKPGIPDIALNTESRRKTPNVVMI-QDGHRTFADAAIGMQVRYPHLVHGQLNDLVGKSTQHPSGGESYTVEALTAMILANAKKFTEEYAAAEIKDVVITVPVYFTPAERLAVERAAQMAGLTVLQLINDGTAAALSHGIFREKPQRLMVYDMGAAKTTATIVEFKQPKMTVLGVGFDRTLGGIEMTNRLRDHLIEMFEKNYKTKVNTNRRAMTKFSKEAERLKQVLSANAEHFAQIESAH----EDIDAKLKVTREDFNHLISDMESRFGEPIEQALRMAQIPIDDIDQFVLMGAGTRVPKVQEIVQKTIGKEIGKFLNTDEAVAMGALFQAAHLSKG-----KVKPFNIEEKVIFPVEITGEKNVVKTLFAANSVYPTHPKTISLTSYSDDFSVALKYGKIESFTKQQVQELVDVEISGLSEALKNRSSVKVSFIVDASGIVRVRRAEALFEPKSGLVGSIASTPNKYDVQEEKRRMEAFAEKERLASERAAVENELESFNFECSQYLEETEFTDYMADEEKTKLEDSVKRIRAWLEDDV----KDTPTKDFTDNLLELKNVVRSVK 767
7 -58.100[D] COG1077 Actin-like ATPase involved in cell morphogenesis  ali follow..  19  9FSSGMAIDLGTANTIVYQKNCGIV---------LREPSVIALIKKDGAFVPYAYGHEA-----------KMMLGRTPTDPLKDGVIADFKGAEEMIKYFIRMVHNRRSFFGPTIVICVPSGSTPVERRAIQEAAESAGGRDVYLIEEPMAAAIGAGLPVTEATGSMIVDIGGGTTEVAVLSLGGIV-----YARSVRVGGDKMDEAIISYIRRHYNLLIGEATAEKIKQEIGTAYVDENAEPRKMEIKGRDLI---------YGIPKEMILNERQIADSLIEPVSQIVEAVKVALEATPPELSSDKGIVLTGGGSLLRNLDFVLSEATKLPVIVADDALSCVALGTGKVLEDFTK-------LKHVLFKQ........................................................................................................................................................................................................................ 345
8 -22.800[E] COG4820 Ethanolamine utilization protein, possible chaperonin  ali follow..  22  31...WLGVDLGTCDVVSMVVDRDGQPVAVCLDWADVVRDGIVWD----------------------------------------------FGAVTIVRRHLDTLEQQFGRRFSHAATSFPP---GTDPRISINVLESAGLEVSHVLDEPTAVADLLQLDN-----AGVVDIGGGTTGIAIVKKGK-----VTYSADEATGGHHISLTFAGNRRISLEE-------------------AEQYKRGHGE----------------------------EIWPTVKPVYEKMADIVARHIEGQG-----ITDLWLAGGSCMQPGVAELFRKQFPAQVHLPQHSLFMTPLAIASSG............................................................................................................................................................................................................................................ 268
9 -16.500[S] COG4457 Uncharacterized protein conserved in bacteria, putative virulence factor  ali follow..  14  249....LILDVGNSHTCGILVEDSRVEFAQAKFGQQSFPSITRVGHEACRMALQRLGTEGSTG----ISSPRRYLGEEERLPVFSPHYSRSSLMTFMLSELLAQALMQINSALRSIILTLPSAMPKPEREIFRQRMNEAIALVWKSMDEATCGQMVYLYNEGKTLRIASIDIGGGTTDLAITQYG----RLLFREG-FKVAGDDILLDIIQLYILPALQATSDGVMDKLFGNDGRMDGQSVLRQQATLQIFMPVGRAILEAYENVDLQVPLVLKLSQLHGEFLSNRMSITQNLRALSE--VVSLYACDVLLLTGRPSRFPGIQALFRHLQPLPNNRILNPKSTAAVGAMLCLLALNLRLAGFYFKAGDFQPYSTICYLGMLSSSHTLNVYYRDIDLDSADYKLPSDVHFQLRGSLSLGFRQLDNDRWPASPLY-SIVEQELARKIAGNSVLSVKLKLAKS-----KQTGLERFELAEAKLQDGSRVPLHHLRLKLNTLASNGSGSPH................................................................................. 1012
10 -16.000[D] COG0849 Actin-like ATPase involved in cell division  ali follow..  11  10...IVGLEVGTSKVVALVGEDGVVNILGSCPAKGIDKGNITDLNAVVTSVQRAIELAESVADCEIISVTLAITGQHIQSWNDS-PIADTEVTQEDIDAALHTASSIKMPEGLVVLHRLPQEYADQQKNIKNPLGFQCKLKIDKVIFSGIATSHSVLTEDEKDLGVCLIDFGAGTMEVMVYT--NGALRFSKV-----YAGNRVTDDIA------------YDLTTSRVEAENIKVKYGSAVTPPRQNPEEQFDVMSIDGSVIE------RCSKTRLSNVTAGRYREILELVKEELIQLKYDLESKQGIVITGGGAQIKDLKECATDVFGLHVRIGNKPQYSTVLGLLQYE............................................................................................................................................................................................................................................ 388
11 -14.400[E] COG4819 Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition  ali follow..  13  9....VGIDIGTTTTQVIF---------------------------SHLELVNRAAVSQVPRYEFIKREISWQSPVFFTPVDKQGGLKEAELKSLILEQYQAAGIAPESVDSGAIIITGESAKTRNARPAVMALSQSLGDFVVASAGESVIAGHGAGASEQRLCRVLNIDIGGGTANYALFDAGK-----ISGTACLNVGGRLLETDS-------------------QGRVVYAHKPGQMIVDECFGAGTDVRSLT----------GAQLVQVTRRMAELIVEVIDGTLSPLAQALMQTGLLPAGVEIITLSGGVGECYRHQPADPFCFADNVQFPAQTVRATVIGAGAHTLSLSGSTIWLE--GVQLPLRNLP----------VAIPIDETDLVSAWQQALIQLDLDPKTDAYVLALPASLPVRYAAVLTVINALVDFVARFPNPHPLL-VVAGQDFGKALGMLLRPQ-LQQLPLAVIDEVIVRAGDYID................................................................................................ 445
12 -12.200[C] COG1069 Ribulose kinase  ali follow..  13  1MAIAIGLDFGSDSVRALAVDCTTGEEIATSV-DSTGSTPAPIDADGNVLALRPEKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVALPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVI-----GTSTCDILIADKQSVGERAVKG--GLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKEQIDASQKQLLPALTEAWAKNVVLDWFNGRRTKGVITDLNLATDA-PLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGARKNQVIMQACCDVLNR-PLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQ............................................................................................................................................................................ 561
13 -11.700[Z] KOG0797 Actin-related protein  ali follow..  14  181..........................................RKYRKMIFGEEALKISPKEPYCLYHPIRR--GHFNVSPHYSAQRVCEDLTAILLEKLHITHKER---FSFHAVIVVPETFDTREKEMLTIVLGELYFNSAVVHQEGLSAVFGNGLTTA-----CIVNIGAQT--STVVCVEDGVS-LPNTEKILPFGGEDICRCLLWIQRHYQKWPQINTDVLAKPIDMLMLNQLKESFCEIRAGELETVATVHSYEEGMPAVPHKTNLTSLNVPPMGIGLAEAITSSILSA-GRIDLRRKLFSSIQLIGGAGLTKGLVAAVEERVLHVLPSRTEPQFVTWKGGAILGIL--------DFGREAWIERHQWMVNGVNKG............................................................................................................................................................................................................. 575
14 -11.300[NU] COG4972 Tfp pilus assembly protein, ATPase PilM  ali follow..  14  8..NIVGIDIGSSSVKVVELSANG-----KQGDFRLEKCASELIERSAVADGNLVNIDAVGSALKRAIAKAGIRSKDAVLAIPASLTESQTVSDELFVQVESEANRLFEGGIGVRVMATVAERVTERVTAAEMA----GLRPIVMDVEENAIQRAM--EMRDMPVVAMFHLGGANSQALFYQGWKELYE------PLSGSGDQLTQSISRLFSLDLLK-------------------AEVKKRKNT-------------------------LPDEYRSQLLKPSLETLAMEVSQAIQLSTSSVGRVDEIVLSGGHASLLGVQTAIQQQTQARYLQRDLPAYIVSAGLALRG............................................................................................................................................................................................................................................ 354
15 -11.200[S] COG4020 Uncharacterized protein conserved in archaea  ali follow..  11  2..TFIGVDHGTTAMRFALIEDEKVELGRAEAAAMSEKEILAAIEREFGIIDLVALTYSMGDGFSAIKDVRK---EGRGLQSIEGAGKKTGGGTRVFDAVRNSEIPAIAIPGLHSGSRVDPRMKVFSHLTSPEK-----------------LGIAYHILCLGYEDFVVSDISSNT---VTLAVVAGKV-IGAIDACIFAPG-PLDLQAIRNVDDRLQTANQAFIEAGTLKMTPYKDREELLKAAGKGEKPALLALDTIALF-----------------------AAMEIASMQLLMKDYG----TTGTVFLAGSVGEVEYVQKKICTHLDQECLS---GKWHAAIGCAEIARDVSAGKKQ................................................................................................................................................................................................................................... 316
16 -10.700[G] COG5026 Hexokinase  ali follow..  12  84.GSYLALDLGGTNLRVCAVEVQGNGKFDITQSKYRLPQELKVGTREALFDYIADCIKKFVEEVHPGKSQNLEIGFTFSYPCVQRSINDGVEGESVGPLLSAALKRVGCNNVRLNAITTGTLVASNYASPGTEIGVIFGTGCNACYIEKFSEIPKLHKYDFPEDMNMIINCEWCDFDNQHVVLPRTKYDVAIDEESPRPGLQTYEKMIAGCYLGDILRRILLDLYEQGALFNGQDVTKIRDPLAMDTSVLSAIEVDPFENLDETQTLFETEEERQFIRRACELIGTRSARLSACGVCALVRKMNKPSMIVGTDGSV--DRLAQAFKDILGEEIGSKVVAEDGSGVGAALVSALEAKGKALTSDI............................................................................................................................................................................................................................... 477
17 -10.600[G] KOG2531 Sugar (pentulose and hexulose) kinases  ali follow..  13  11...FLGFDLSTQKLKA---------VLLGSSLEVVAAAEVKFDRTTGGANAGSIKNEYFVQPVMWVKAMDIVLDRLVMQQADLSTVAAISGSGQTLQNLDSEKFLHAQIDDSAFVVNRTPIWMDATEMAVGGKLNMVELTGSKCYERFTGPQIRKIYQQRCHSSFISSLFLGNLLDIRKKNWSKECLNVCAPDLDKRLDIPVSPNSILGNVSPYFVERFSFS-GDNPSALSGMLVGSSWLTISMGTSDTLMMSLKEPLNWEEGHI-MNKKTTGGDWDKFIRALVEGQMLHHRAVAEDLGYKFGPETQILVTGGASVNKSILQTIADVFNAPVHIQDEGFEAALLGAAYRSAYALYLQEAGDGVTPLCYRDYILSLTSNKLS-EIYAPMLQRYREMARVLSNPNT...................................................................................................................................................................................... 552
18 -9.660[G] COG1070 Sugar (pentulose and hexulose) kinases  ali follow..  12  14...LMALDAGTGSIRAVIFDLEGNQIAVGQAEWRHLEGIVLYNNEGTPIWACANVDARAAREVSELKELHNNTFENEVYRATGQTLALSAIPRLLWLAHHRMISDWLAYMLSGELAVDPSLLDLTIRDWKPALLDMAGLRADILVSSQAAELC--GLKVGTPVVVGGGDLGLGVVRPAQTAVLGGTFWQQVVNLAAPVSISFFTGLTMRWFRDAFAEEKLIAERLGIDTYTLLEEMASRVP-RMRFKTWYHAAPSFINLSIDPDKCNKATLFRALEENAAIVSACNLQQI-------ADFSTIHPSSLVFAGGGSKGKLWSQILADVSGL-PVNIPVVKEATALGCAIAAGVGAGIFSSMAETGERLV.......................................................................................................................................................................................................................... 482
19 -9.340[Z] KOG0676 Actin and related proteins  ali follow..  12  6..AVLVIDNGSGMCKAGFAGDDAPQVFPSIVGRPRHQGMMEGMHQKESYVGKEAQSK------RGMLTLKYPMEHGIITNWDDMEKIWHHTFYNELR---------VAPEEHPILLTEAPLNPKANREKMTQI-ETFNTPAMYVAIQAVLSLYTSGRTTG-----IVMDSGDGF--THTVPIYEG-NALPHATLRLDLAGRELTDYLMKILTE---RGYRFTTTAEQEIVRDIKEKLCYVALDSEQEMAMAASSSSVEKSYELPDGQVITIGNERFEALFQPIHKTTFNSIVKS--DVDIRKDLYTNTVLSGGTTMYPGIAHRMQKEITALAPSIMKRKYSVWVGGSILASL.......................................................................................................................................................................................................................................... 349

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 4 7 1   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Wooley JC, Godzik A. Probing metagenomics by rapid cluster analysis of very large datasets. PLoS ONE. 2008;3(10):e3375. Epub 2008 Oct 10.