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Query: gi|238922452|ref|YP_002935965.1| hypothetical protein (EUBREC_0026) [Eubacterium rectale ATCC 33656], from E.rectale

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDKYEYNLKLDQIKALSAEEGYMSAAEIADSINWNKIKNVNTLVKIGEIYEKAERYQDARDILLMAYDRSPIGRMIIYRLAEVAIKMGDYDAATEYYDEFVEIAPHDDMKYVLRYAIKKGQGASFDELITILEEYKDEEYTEEWAYELAYLYHKAGKADKCIDACDELILWFGDGPYVERALELKMLYQPLTKAQEEKYRRFKAEKEKPAKIKDEAEVTEIGAMEMVKGGEIVHDDVTIPQITVNQEKFNTVNLQQEIAKGMQQIMEAKGKNEVADTMDTIKKIVEDIPYLKLEKEQEEYAQQPEETEHIATDEEIDGSLKLNFKELLGEDADGQMSMVMSEKTQLEHQITGQMSIQDVLEEWEKTRHAAEIALKEAEQQKLESAKARALQEAGDIMERLNDVIPKLDAGVTPKELLEEEYLKVPVDIIEQKAAVKEPEEEQKPDMQELYAEETVDEVQEPQEAPEDTIDEAQEPQEAPEEAIEEAIEEVQESREVPEEAADEAREPVGEPEDIIMAEESEKDEILMQPTTMMPEITDDMLNVDDDTSDDETSQEKENVSEKRDFDHVTSFIEQEIAKMTAKNPGLEKKLDMAKTRKMPDISLPEDLDSEEDDSKLKETKHIKELTSEQKAIFSYFIPVKGMEDQICKAYNAVLDHFNRKENASTGNLIIQGEQGCGKTMLATSFIKVLQKDGEQLTGKMGKIDAAALNKKDVQQVVRKITGGCLIIERAGDIDRSIAAQLSFLMEHDITGTLYILEDTSKGIKKALSMDEGFASKFTEKISVPIFTNDELVLFAKSYSAELGYKIDEMAILALHNRISNIERIDQATTLTEVKDIIDEAIDREAHSGLKKAISILTARRYTDDDRIVLKEDHFREKLast
1 -16.300[R] COG2607 Predicted ATPase (AAA+ superfamily)  ali follow..  8  38.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................QSAGKKGFLEHLPDPHTFPLVRLAGVGRQTELLVRNTEQFIV------GRPANNVLMSGARGTGKSSLVKALLHEYADKG-----RLIEVDKSDLIGYLLTLLKECPEKFIVFCDDLSFESGDETYKALKTLSQRCANVLVYATSNRRHLKEAVEEKISLSDRFGLWLSFYPFDQNDYLAAVQNWLEDFGVPYDE----TAQMAALQWAQTRGSRSGRSAWQFACDWAGRLPKQ.............................. 284
2 -14.900[R] COG4105 DNA uptake lipoprotein  ali follow..  15  55.........YNQGLANLNAGRLDEASKKFDAVD--SEWARKSMVMGAFADYRKGSYDEAISSYLALYPSTDDAPYAQYIIGLSYYRQKEARQTLQTMQDLVTRWPTSEYVDDAKEKIRFANDAAVKRFRTVVENYSNTRHVEEALARLTESYYAMGLTSEAQTAAAVLGTNYPDSPWYKDSYKLLQS.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 266
3 -14.500[L] COG2255 Holliday junction resolvasome, helicase subunit  ali follow..  10  3................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EADRLISAAVINDEESIDRAIRKLLTEYVGQPHVREQMEIFIQAAKQR-----GDALDHVLIFGPPGLGKTTLANIIANEMGVNLRTTSGPVLEKAGD------LAAMLTNLPHDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMFTLIGATTRAGSL---TSPLRDRFGIVQRLEFYQVADLEHIVSRSAKCLGLELTPEGAHQLARRSR--------GTPRITNRLLRRVRDFAEVR.............................. 237
4 -14.000[U] COG5010 Flp pilus assembly protein TadD, contains TPR repeats  ali follow..  11  72RNPKDREAGLNYANLLRMTGRNEQALAVMQQVAIYHPADREVLGAYGKAQAAAGQLEQALATISRAQTPDRPDWKLKSAEGAILDQLGRSAEARLRYREALDLKPNEPSVL--NLGMSYLLTKDLRTAETYLKSAASQPDAGSSVRQLALAVGLQGRFQEAETIAGQEL--EANVAYLRSVLSQQGAWKQLAKAD.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 269
5 -13.800[L] KOG0991 Replication factor C, subunit RFC2  ali follow..  15  45......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VKLNEIVGNEDTVSRLEVFAR----------EGNVPNIIIAGPPGTGKTTSILCLARALLGPA--LKDAMLELNAS--NDRGIDVVRNKIKMKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALA---NASDKII---EPIQSR--AVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAI-NNLQSTFSGFGFINSENVFKVCDQHCVNANIDEAYKILAHLWHLGYSPEDII.......... 296
6 -13.400[L] COG0470 ATPase involved in DNA replication  ali follow..  10  22......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ETLDEVYGQNEVITTVRKFVD----------EGKLPHLLFYGPPGTGKTSTIVALAREIYGKN--YSNMVLELNAS--DDRGIDVVRNQIKDKLIILDEADAMTNAAQNALRRVIERYTKNTRFCVL---NYAHKLT---PALLSR--TRFRFQPLPQEAIERRIANVLVHEKLKLSPNAEKALIELSN--------GDMRRVLNVLQSCKATLDNPDEDEI......................... 227
7 -13.200[D] KOG1126 DNA-binding cell division cycle control protein  ali follow..  8  383EEVFQKLRDLSP-TALWHLQKSVPLSYLAHETLETNPYSPESWCILANCFSLQREHSQALKCINRAIQLDPTFEYAYTLQGHEHSANEEYEKSKTSFRKAIRVNVRHYNAWYGLGMVYLKTG-RNDQADFHFQRAAEINPNNSVLI-IGMIYERCKDYKKALDFYD....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 557
8 -13.100[O] KOG0741 AAA+-type ATPase  ali follow..  13  217...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KMGIGGLDKEFSDIFRRAFEIVEQMGCIHVKGILLYGPPGCGKTLLARQIGKMLNAR-------PKVVNGPEILNKYVGESEANIRKHIIIFDEIDAIHDTVVNQLLSKIDEQLNNILVIMTNRPDLIDEALLR----PGRLEVKMEIGLPDEKGRLQILHIHTAR----MRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHIKA--STKVEVDMEKAESLQVTRGDFLA. 482
9 -13.100[R] COG1223 Predicted ATPase (AAA+ superfamily)  ali follow..  10  88........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ESDPRVIETEIVRDITLDDVVGQEEAKRKAKVILEYLRNPEKFGKWAPKN-VLFYGPPGTGKTMMAKALTPFLSVKSTKLIGEHVGDGARRV--HELYERARQLAPCIVFLDEFDAIASEIVNALLTELDGTNSNEGICTIAATNRVELL---DASIRSRFEEEIEFRLPSYEERLEILRRNLEEFPVPVK----------LELVAAASEGFSGRDLVEKVIKASLHKAIA----------------EGKDKIETEDLLT. 334
10 -12.900[L] KOG0990 Replication factor C, subunit RFC5  ali follow..  10  2........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TELTSAMDIDVDEIQPRKPINKGKDVVGFGPPPQSKATPWVEKYRPQSLDDVAAHRDIIDTIDRLTN----------ENKLPHLLLYGPPGTGKTSTILAVARKLYGPK--YRNMILELNAS--DDRGIDVVRQQIQDKLVLLDEADAMTKDAQFALRRVIEKYTKSTRFALI---NHVNKII---PALQSR--TRFRFAPLDGVHMSQRLKHVIEAERLVVSDCGLAALVRLSN--------GDMRKALNILQSTHMASKE............................... 249
11 -12.800[L] COG2812 DNA polymerase III, gamma/tau subunits  ali follow..  13  13......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................QKLQDVVGQEHITKTLQNALVQEKFSHA---------YLFSGPRGTGKTSAAKIIAKAINCEQAPIAEDVMEIDAASNNGDEIRDIRDHVK-KVYIIDEVHMLTTGAFNALLKTLEEPPSHAIFILATT--EPHKIPLTIISRCQRF----DFKRISNDALVGRMKEILTHEGIEAEDEALVLVARAAE--------GGMRDSLSLLDQAISFADERVTVEDVLAITG--VSHEVLTQVVESAQKGE 260
12 -12.600[U] COG3267 Type II secretory pathway, component ExeA (predicted ATPase)  ali follow..  13  40.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GDGGGFAMLTGEVGTGKTTVARAILASLPG-----KTRAGMILNPTFSDLELLEAICDEFE-LLMIDEAQHLAPDVLEQLLTNLETESHKLLVLLIGQPE-LQEKLRLPQQLAQRITGRYHLLPLNEEQTADYIRFRIEQASGNFNRKACQWIAEQTHGIPRL--------INLVCDAALKQAYQAGEPTLSLARIKLACQE.............. 264
13 -12.400[KE] COG3283 Transcriptional regulator of aromatic amino acids metabolism  ali follow..  12  192.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LQNLSTQDLSAFSQIIAVSAKMKHVVEQARKL--------AMLSAPLLITGDTGTGKDLFA----YACHQASPRSAKPYLALNCASIPEDAVESFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRV-VICATQKNLVELVQKG-LFREDLYYRLNVLTLNPQDIMPLTELFVARFADEQGVPRPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELR........................... 436
14 -12.300[KT] COG3604 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains  ali follow..  16  191........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SVEIIGNSGPMLAMKADIDVV--------APSQFNILIHGETGVGKELVA----RTIHQRSNRKRQPLVYVNCAAIPENLLESELALADGGTLFLDEIGELPLSAQSKILRALQNHEIQPV-ILAATNRDLKKEVEAGRFRADLY-YPIYVPPLREGDLSLLAGYFVEQARRKLGITQLKLHGDVLSQLIQYPWPGNVRELEHVINRAALKAKARQRG........................... 431
15 -12.200[S] KOG3060 Uncharacterized conserved protein  ali follow..  17  1............MSLDYEKMSWSDVRDQFRTWREETGRHSEEVVQLWVILEQTARFDIATKCTKQLSLEFPGSLRVMKFKAMRYEALEQYDEADEVLDAIIAKDETNAAPRKRKIAILKARG-RRLEAIKELNEYLKKFMSDQEAWELCNMYLAEGEFGKAAFCMEEVLL-MGGVENMESARTYYSQALKLNPHNLRAL...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 227
16 -11.900[G] COG2956 Predicted N-acetylglucosaminyl transferase  ali follow..  13  55VDLFLDMLKEDT-NLFRSRGEVDRAIRIHQTLSLTYEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKAIDVAERLVKLGKDKQRVEIAHFYCELAASDDLDRAMTLLKKGAAADKNSARVSMMGRVFMAKGEYAKAVESLQRVI.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 241
17 -11.900[L] KOG2028 ATPase related to the helicase subunit of the Holliday junction resolvase  ali follow..  9  10...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SSDLAAEALTATGGDSIQKATDWILSHRSSPQSTATLQPKLDRFLRLHPKALAPAMGDDSSKRPNPKTQIHVAADDSNKRHKLSSSSHRQHQPLSERMRRTLDDVVGQDHLSSLLRSAVE----------SNRLPSIVFWGPPGTGKTSIAKSLINSSKDPS---LYRFVSLSAVTSGVKDVRDAVESAK--VLFMDEVHRFNKSQQDTFLPVIEDGSILFIGATTENPS-----FHLITPLLSR--RVLTLNPLKPNHVETLLRRAVDDNSVEVDDSVIEFLANNCD--------GDARVALNALEISATMATTRAGTD.......................... 320
18 -11.800[DL] KOG2035 Replication factor C, subunit RFC3  ali follow..  15  39..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................HLLFCGPSGAGKKTRIKCLLRELYGVGVEKTQEMTPSDVGIYDRVVVQDLVKEMAQKVVVLCEADSLTRDAQHGLRRTMEKYANNCKIVLS---ESLSRII---EPLQSR--IIINVPAPTDEDVTKVLRKVIERESFLLPENVLQKIVEKSEG--------NLRRAILMTEALRMENES............................... 241
19 -11.800[S] COG4916 Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain  ali follow..  9  24..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PKHFGEVRADISQVGK--------HLLIEGPSGIGKTCVVFKVFEELQWS---QGRDFTYVGCRDQNAEQIIDDFLKNSPCVLVIDDFHLLSQAKRMEIGSTLKEQAEPAKVILIGIPTAGVSLLSDAYDLGPRLG-SYALTRASDVEIDKLISEGEQALAVLFEDRDVLLLAQYVTQDDAKILTFDILGIRGRLMAELTQRYLPIARTFAKGKRWRPGGNKPYLEI........ 272
20 -11.700[O] COG0464 ATPases of the AAA+ class  ali follow..  10  428............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................REAAMSALRRILPKINLNEPEISKEILDALQVTREDFENALKDVQPSAIREILIEVPNVSWEDVGGLERVKELLKEVVEWPLKNPESYRDEAPKGVLLYGPPGTGKTLLAKAIAHESDA-------NFITAKGSDLLSKWYGESEKRIAESIIFLDELDSLTARILNQLLSEMDGLEELRAVVVIGATNRPDII---DPALLRRFDELILVPVPDEGARREIFRVHTKNMALAED----------IEKLVSFTDQYTGADIAAVCKKAGRHALREDLHA---------------KKVRQKHFLQ. 726
21 -11.400[KT] COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains  ali follow..  11  255..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................HTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRI--------APSPSSVMVVGESGTGKEVVA----RAIHKLSGRRNKPFIAINCAAIPEQLLESLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEARE---IRIISATNQNLAQFIAEG-KFREDLFYRLNVIPITQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEILRKHRWPGNLRELSNLMEYLVNVVPS............................... 506
22 -11.300[O] KOG0730 AAA+-type ATPase  ali follow..  10  445.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ADLAALCTEAALQCIREKMDVIDLEDDSIDAEILNSMAVSNEHFHTALGNSNPSALRETVVEVPNVSWEDIGGLENVKRELQETVQYPVEHPEK-GMSPSKGVLFYGPPGCGKTLLAKAIANEC-------QANFISVKGPELLTMWFGESEANVRECVLFFDELDSIADRVLNQLLTEMDGMNAKKTVFIIGATNRPDII---DSALLRRLDQLIYIPLPDEDSRLNIFKACLRKSPVAKD----------VTALAKYTQGFSGADITEICQRACKYAIRENIEKDIEEAMEEDMVDDEVSEIRAAHFEE. 775
23 -11.300[O] KOG0726 26S proteasome regulatory complex, ATPase RPT2  ali follow..  11  164.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DDTDPMVTVMKLEKAPQETYADIGGLDTQIQEIKESVELPLTHPEY-GIKPPKGVILYGPPGTGKTLLAKAVANQT-------SATFLRVVGSELIQKYLGDGPKLVRESIVFIDEIDAVGQRTMLELLNQLDDSRGDVKVIMATNRIET------DPALIRRIDRKIEFPLPDEKTKRRIFTIHTSRMTLAED----------LSELIMAKDDLSGADIKAICTEAGLMALRE-----------------RRMKVTNEDFKK. 420
24 -11.300[LD] KOG2227 Pre-initiation complex, subunit CDC6, AAA+ superfamily ATPase  ali follow..  9  3.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TNAGTSLSSYKHIVAIGTTVKSESLESAAYEIPRKRKMRSDSAAVSGNSVSTPKKLKSHLPSSVPNPGMSEKEVVEDSNEILRYPVNLAVSDCLGTKSKWSPRDEEQMRAVKEALHVSKAPILCREDEQIRIFEFVKGCID---QQKAGSLYICGCPGTGKSLSMEKVVQQVGTQAGLPPVDTLSVNCTSLSKTTFSKILGEIKPGLIIADEMDYLDRGVLYDLFMLTTLPFSRCILIGVANAIDLADRFLPKLKSLNCKPMVITFRAYSKDQILRILQERLRV---AFQPKALELCARKVAAASGD-----MRKALCVCRSALEILEIETRGSTGP---ESQGPTPDDSVVRMDHMAA. 390
25 -11.200[KT] COG4650 Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain  ali follow..  13  176.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................QQTLDFLKSGIATRNPHFNRMIEQIEKV-------AIKSRAPILLNGPTGAGKSFLARRI-LELKQARHQFSGAFVEVNCATLRGDTAMSLLRSANGGMLFLDEIGELGADEQAMLLKAIEEKTFYPF-LIAGTVRDLRQLVAEG-KFREDLYARINLWTFTLPGLRQEVERHASLTGDSVRFNTARRAWLAFATSPQATWRGNFRELSASVTRMATFATSGRIT........................... 432
26 -11.200[KT] COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain  ali follow..  13  217.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DMLGQSPQMEQVRQTILLYARSSAA-----VLIEGETGTGKELAAQAIHREYFARHDARQGKFVAVNCGAIAESLLEALFEIAHGGTLFLDEIGEMPLPLQTRLLRVLEEKEVTRV-VISATHCNLEEDMRQG-QFRRDLFYRLSILRLQLPPLREFLKVSLAALSAPFSAALRQGLQASETVLVHYDWPGNIRELRNMMERLALFLSVEPTPDLTPQFLQLLLPELARESAKIPAPRLL 495
27 -11.200[O] KOG0737 AAA+-type ATPase  ali follow..  10  406.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ANEIGVTFADIGSLDETKESLQELVMLPLRRPDLGLLKPCRGILLFGPPGTGKTMMAKAIANE-------AGASFINVSMSTITSKWFGELAAKVSPTIIFVDEVDSMMRKIKNEFMTHWDSNAGDRILVLAATNRPFD-----DEAIIRRFERRIMVGLPSVESREKILRTLLSKE--KTENLDFQELAQMTDGYSGSDTTAAYRPVRELIKQECLKDQERRKREEAEKNSEEGSEAKTLRPLSMEDMKV. 685
28 -11.100[S] COG4700 Uncharacterized protein conserved in bacteria containing a divergent form of TPR repeats  ali follow..  10  74...................RKLTEELAIAETNQ----------YALANELARLGRYHEAVPHYQQALSGIFAHEAMMLSLAQAQFAIQEFAACQQTLEDVMRYNPDQSADGHLLFARTLAAQEKYADAESEFEVLISYYPGPQARIYYAEMLAKMSRLREANEQYVAVV.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 217
29 -11.100[DO] KOG1174 Anaphase-promoting complex (APC), subunit 7  ali follow..  12  286........RLEDVENLGCRKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQEKAKTLLDKALTQR------VKKAELLSREQKYEDGIALLRNALFLVAVNEY-QEAMDQYSIALSLDPNDQKSLEGMQKMEKEESPTDATQEEDVDDMEGSGEEGDLEGSDSEA.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 552
30 -11.100[O] KOG0728 26S proteasome regulatory complex, ATPase RPT6  ali follow..  12  128.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NKVDPLVSLMMVEKVPDSTYEMVGGLDKQIKEIKEVIELPVKHPEL-GIAQPKGVLLYGPPGTGKTLLARAVAHHT-------ECTFIRVSGSELVQKFIGEGSRMVRESIIFMDEIDSIGQRTMLELLNQLDGFEATKNIKVIMATNRIDIL---DPALLRRIDRKIEFPPPNEEARLDILKIHSRKMNLTRG----------LRKIAELMPGASGAEVKGVCTEAGMYALRE-----------------RRVHVTQEDFEM. 384
31 -11.100[R] KOG1128 Uncharacterized conserved protein, contains TPR repeats  ali follow..  17  418LGQMDKAETL--IRRLIEQKPFTKAIELSDD------RNARAHRSLGHLLLMDKKFEEAYKHLRRSLELQPIQLGTWFNAGYCAWKLENFKESTQCYHRCVSLQPDHFEAWNNLSAAYIRHG-QKPKAWKLLQEALKYNYEHPNVWEYMLLSVDVGEFSQAIQAYHRLL.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 596
32 -11.000[L] KOG1514 Origin recognition complex, subunit 1, and related proteins  ali follow..  8  5..............................................................................................................................................................................................................................................................LSSKAKTFKSPTKTPTKMYRKSYLSPSSTSLTPPQTPETLTPLRRSSRHVSRKINLGNDPIDLPGKESVEEINLIRKPRKRTNDIVVAEKSKKKKIDPEVSFSPVSPIRSETKKTKKKKRVYYNKVEFDETEFEIGDDVYVKRTEDANPDEEEEEDPEIEDCGFHLNCLKPPLKEVPEGDWICQFCEVKKSGQTLVVVPKPPEGKKLARTMKEKLLSSDLWAARIEKLWKEVDDGRQRHNLKRELYLTNDFADIEMECVLRHCFVKCPKEFSKASNDGDDVFLCEYEYDVHWGSFKRVAELADGDEDSDQEWNGRKEEEIDYSDEEIEFDDEESVRGVSKSKRGGANSRKGRFFGLEKVGMKRIPEHVRCHKQSELEKAKATLLLATRPKSLMEEITAFIKGSISDDQCLGRCMYIHGVPGTGKTISVLSVMKNLKEAGSVSPYCFVEINGLKLASPEYSVIYEGLSGHILLIDELDVLNQSVLYNILDWPTKPNSKLVVLIANTMDLPEKLL---PRISSRMGQRLCFGPYNHRQLQEIISTRL-EGINAFEKTAIEFASRKVAAISGD-----ARRALEICRRAAEVADYRL---------KKSNISAKSQLVIMADVEV. 653
33 -11.000[DO] KOG1155 Anaphase-promoting complex (APC), Cdc23 subunit  ali follow..  19  334TDKYRPESCCIIGNYYSLKGQHEKAVMYFRRALKLNKKYLSAWTLMGHEYVEMKNTPAAIDAYRRAVDINPTDYRAWYGLGQAYEMMGMPFYALHYFRKSIFFLPNDSRLWIAMAKCYQTEQLYLEEAIKCYKRAVNCTDTEGIALQLAKLHQKLGRNEEAAY-------------YFEKDLERMDAEGLEGPNMFEAL...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 521
34 -11.000[O] KOG0727 26S proteasome regulatory complex, ATPase RPT3  ali follow..  12  135.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PEADSSISLLSQSEKPDVSYNDIGGCDIQKQEIREAVELPLTHHEL-GIDPPRGVLLYGPPGTGKTMLAKAVANHT-------TAAFIRVVGSEFVQKYLGEGPRMVRDAIIFIDEVDAIAQRILMELLNQMDDQTVNVKVIMATNRADT------DPALLRRLDRKIEFPLPDRRQKRLVFQVCTSKMNLSDE----------LEDYVSRPDKISAAEIAAICQEAGMHAVRK-----------------NRYVILPKDFEK. 391
35 -11.000[QK] COG3284 Transcriptional activator of acetoin/glycerol metabolism  ali follow..  14  329...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LRRLGGDAPVIAALQAKAAKLARTRLP-----ILIQGETGTGKEHLARAIHEGSGLEGPFVAINCAAIPEQLISAKGRKGLIEQADGGTLFLDEIGDMPLALQSRLLRVLAEGE---IRIVSASHRPLQTLVSQGAFREDLYAATLTLPALRDPDFDWVLEQLLKRHG-ILSPAALSAL-------KAHDWPGNIRELDNVIGVAAALAENGVVE........................... 564
36 -11.000[O] COG1222 ATP-dependent 26S proteasome regulatory subunit  ali follow..  10  140.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DAKPDETYEDIGGLERQIEELNEAIVLSLTHPER-NIKPPKGVLMYGPPGTGKTLMARACASKT-------NATFLKLAGPQLVQMYIGDGARLVRDTIIFIDEIDAIGQRTMLELLNQLDGFSSSEEVKIIAATNRVDIL---DPALLRRLDRKIEFPLPNTLGRKRILQIHARKMSVRDD----------FDELARSTEGFNGAQCKAVCVEAGMAALRK-----------------EKTEISQNDFMD. 384
37 -11.000[B] KOG1156 N-terminal acetyltransferase  ali follow..  19  23HKQYRNGLKCKQILSLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASW-IGYAIAYHLLEDYEMAAKILEEFRKTEYSELLLYQ-NQVLREAGLYREALEHLCTYEVEETKGELLEDAADVYRGLQERNPENWAYYKGL................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 264
38 -10.800[L] KOG1968 Replication factor C, subunit RFC1 (large subunit)  ali follow..  9  12..................................................................................................................................................................................................................................................................................GGNAQKKPKVSPTPTSPKPKRSLKKKRIVLSDDEDGTIENSKVPASKSKVQKRNESEDISHSLPSIVHEDDKLVGSDGVSTTPDEYFEQQSTRSRSKPRIISNKETTTSKDVVHPVKTENFANDLDTTSDSKPVVHQTRATRKPAQPKAEKSTTSKSKSHTTTATTHTSRSSKSKGLPRFSDEVSQALKNVPLIDVDSMGVMAPGTFYERAATTQTPGSKPVPEGNSDCLSGISFVITGILETLTRQEATDLIKQYGGKVTGAPSVRTDFILLGENAGPRKVETIKQHKIPAINEDGLFYLITHLPASGGTGAAAQAAQQKKEQEEKKILETVARMDDSNKKESQPSQIWTSKYAPTSLKDICGNKGVVQKLQKWLQD-FNKPGPDGLGLYKAVLLSGPPGIGKTTAAHLVAKLE---------DVLELNASD-SKRLLDEQLFGVTDSVLIMDEIDGMSSGDVGQLNMIIKKSMIPIICICNDAHPKLRPL--------DRTTFDLRFRRPDANSMRSRIMSIAYREGLKLSPQAVDQLVQGTQ-----------SDMRQIINLL..................................... 584
39 -10.700[O] KOG0651 26S proteasome regulatory complex, ATPase RPT4  ali follow..  10  130.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................REVDPLVYKMSHEDPGNISYSDVGGLAEQIRELREVVELPLINPEL-GITPPKGCLLFGPPGTGKTLLARAVASQL-------DCNFLKVVSSAIVDKYIGESARMIRECIVFMDEIDAIGQRTLMELLNQLDDSLGKVKVIMATNRPDT------DPALLRRLDRKIEIGLPNEQSRLEILKIHSNKITKHGE----------FEAVVKLSDGFSAADLRNVCTEAGMFAIRA-----------------EREFVIDEDFMK. 386
40 -10.700[M] KOG3364 Membrane protein involved in organellar division  ali follow..  15  1MTKVDFWPTLKDAYEPLYPQQLEILRQQVVSE--GPTATIQSRFNYAWGLIKSTDVNDGVKILTDIYKEAESRRECLYYLTIGCYKLGEYSMAKRYVDTLFEHERNNKQVGALKSMVEDKIQKETLKGVVVA......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 135
41 -10.600[S] KOG4340 Uncharacterized conserved protein  ali follow..  11  15.........TALVYRLIRDARYAEAVQLLGQLH----ELEQYRLYQAQALYKACLYPEATRVAFLLLDNPAYHSRVLRLQAAIKYSEGDLPGSRSLVEQLLSGGDNETDGQVNLGCLLYKEG-QYEAACSKFSATLQAS-QPDLSYNLALAYYSSRQYASALKHIAEII.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 178
42 -10.600[O] KOG0733 Nuclear AAA ATPase (VCP subfamily)  ali follow..  11  402...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NEISPLNKLDLNSDPRFNELDSDMALDSNDSLPLDHSSIIQRYLNAHPDPLSPEELEPLAICPQDFIEALAKVQPSSKREGFATVPGVSWNNIGALKSIRVELQMAIVQPIKRPELYQSSAPTGVLLWGPPGCGKTLLAKAVANESKA-------NFISIRGPELLNKYVGESERAVRQCVIFFDELSEASSRVVNTLLTELDGLSDRSGVYVIAATNRPDII---DPAMLRRLDKTLLVDLPDAHERVEILKTLTKQTPLHEENLDVLGRDERCSNFSGAD-------LAALVREAAVTALRSAVFADIASNEPEITQHSALIRVTNADFEL. 746
43 -10.300[S] KOG2796 Uncharacterized conserved protein  ali follow..  13  184WRSRLGRVMYSMANCLLLMKDYVLAVDAYHSIKYYPEQEPQLLSGIGRISLQIGDIKTAEKYFQDVEKVTQKKIMVLMNSAFLHLGQNNFAEAHRFFTEILRMDPRNAVAN--NAAVCLLYLGKLKDSLRQLEAMVQQDLHESVLFNLTTMYESSRSMQKKQALLEAVAGKEGDS.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 370
44 -10.300[R] KOG1124 FOG: TPR repeat  ali follow..  16  157ARAQERPLAVNKAKVLARNFRYKDAEKILEKCIAYWPEDGRPYVALGKILSKQSKLAEARILYEKGCQSTQGENSYIWCWAVLENRLGNVRRARELFDAATVADKKHVAAWHGWANLEIKQG-NISKARNLLAKGLKFCGRNEYIYTLALLEAKAGRYEQARYLFKQATSWLAWAQLYPAARKLFEKAVQASPKNRFAW...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 376
45 -10.300[NU] COG3063 Tfp pilus assembly protein PilF  ali follow..  12  21........................STSYRPSRAEKANQVSNIKTQLAMEYMRGQDYRQATASIEDALKSDPKNELAWLVRAEIYQYLKVNDKAQESFRQALSIKPDSAEINNNYGWFLCGRLNRPAESMAYFDKALADPTYPTPYLNKGICSAKQGQFGLAEAYLKRSLTKMLAGQLGDADYYFKKYQSRVEVLQADDL...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 213
46 -10.300[R] KOG1129 TPR repeat-containing protein  ali follow..  12  189TKQLQSSLEQKKLIEYNRVDQPMAALKTYSAGLEVFPENVTMLTGMARVQEALGEYDESVKLYKRVLDAESNNIEAIACVATTYYYGGKPELAMRYYRRILQMGVSSPELFLNIGLCCMAAQ-QFDFALSSILRAQSTMTDDVAAYNIGQILVDIGDLVSAARSFRIALLKHREGKI-DEARSLYSSATSKNPYMFEGNYNL................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 414
47 -10.200[O] KOG0652 26S proteasome regulatory complex, ATPase RPT5  ali follow..  12  151.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKER-GVRPPKGVLLYGPPGTGKTLMARACAAQT-------NATFLKLAGPQLVQMFIGDGAKLVRDCIIFIDEIDAIGQRTMLELLNQLDSSDERIKVIAATNRADI------DPALMRRLDRKIEFPHPTEEARARILQIHSRKMNVHPD----------FEELARSTDDFNGAQLKAVCVEAGMLALRR-----------------DATEVNHEDFNE. 407
48 -10.200[R] KOG2295 C2H2 Zn-finger protein  ali follow..  7  158................................................................................................LKQFLDTQDENDSEVMRKYTEYKTD--------QQLNEFFVAHKDEEWFKN----YHSEEQRGFLQRRTDVFMELLENGTIGSVKVDSSQADALIRVLDTCVIKLEGGTDEDLKVLDEKPKDPVVYERKAEQMQSVKEVEKTINSPKEEMSEADPVSTQRKPVRPVNSDGENWDDDDAENSAPKKELAEDSKDSDSKPEDKQLNKKKTKKRKRNSSDDDSSSSESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRTSS....................................................................................................................................................................................................................................................................................................................................................................................................................................... 516
49 -10.200[U] KOG0547 Translocase of outer mitochondrial membrane complex, subunit TOM70/TOM72  ali follow..  15  398FKFFQKAVDLNP-QMYFILQDYKNAKE-----DFQKAENVYPYIQLACLLYKQGKFTESEAFFNETKLKFPTLPEVPTFFAEILTDRGDFDTAIKQYDIAKRLEEVQEKIHVGIGPLIGKATIKFNAAIKLLTKACELDPRSEQAKGLAQLKLQMEKIDEAIELFE-------------DSAILARTMDEK.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 600
50 -10.200[U] KOG3081 Vesicle coat complex COPI, epsilon subunit  ali follow..  16  118...............FMHEEDYNETLKHT-----HAGGTMDLYALNVQIFIKMHRAEYAEKQLRVMQQIDEDHTLTQLASAWLNLAVGKIQEAYLIFEDFSEKYPMTCLILNGKAVCCMQMG-NFDEAETLLLEALNKDAKDETLANLVVCSLHVGKSSS--RHLSQLKLSHPEHILVKRVSSAEDNFERAVQL........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 291
51 -10.200[O] KOG0729 26S proteasome regulatory complex, ATPase RPT1  ali follow..  12  155.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPER-GIEPPKGVLLFGPPGTGKTLCARAVANRT-------DACFIRVIGSELVQKYVGEGARMVRECLIFFDEIDAIGQRTMLELINQLDDPRGNIKVLMATNRPDT------DPALMRRLDRKIEFSLPDLEGRTHIFKIHARSMSVERD----------FELLARLCPNSTGAEIRSVCTEAGMFAIRA-----------------RRKIATEKDFLE. 411
52 -10.100[L] KOG2228 Origin recognition complex, subunit 4  ali follow..  7  2........................................................................................................................SSSPFTN----LGNLD------EAIYENKENEYQTNITNE------------SNVQNLSSGNDDQQYPNSTNDDANN------GLTASQAKLQDIAAVTLFQDNNISTTTLAPPSPSPLRLNEAPRRRGRPRKYPPKPIDEGSEPIIKRKRGRPPKIKSSSPSTKLDDPLKPKRGRGRPRLHPLPVVQPSVDEGTTQNNLQMGLDEPNIIEGFAEGHANLSELKPKRGRGRPRKIKPEEGSSSQNGLSPLVVLPAKRGRGRPPLHRSEQKIANTPISNNVTVESTGTNLHTHSQLNPENEQSSSEFYSLNPQSEIRKEVVVTDQPLFSTADVPVKRKRGRPPLNKPKILFGTSTENKIDENRPKRGRGRPRLERPSGLPLDSKSQSLFKRKRGRPPKIASGIVPLSAFTRKHEDMLHDSDALSLKHFAITSPNNQQFLNNQQRESAPLLPRKRGRPPKKRQENAEIRNITPGLTDSSVHSSSATPQSESSSPNSVSPLLPSSDRLPLLRQSQFTPLVGHMDEQTKLYQWVRQTIV------LGEGNSVIIVGPRGSGKSVLVDDILSRAAQE---EKSYVVRLNGTYQTDDKLREISRQLSI-IFVLEEFDLFRQMLLYNLFDIAQSRKAPILIIGLTTRYDCSESLE--KRVKSRFSHMPMRPPSSLSEFEQILKSVLYVSDEGGKDQIITCWNQRVDEL--------LSDTRSHLHKLVQH.................................. 796
53 -10.100[O] KOG0736 Peroxisome assembly factor 2 containing the AAA+-type ATPase domain  ali follow..  12  689........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................WDDVGGLEDVKTSILDTVQLPLLHKDLSGLRKRSGVLLYGPPGTGKTLLAKAVATECS--------NFLSVKGPELSEKNVRDIFEKARSAVIFFDESGGVMDRVVSQMLAEIDDSSQDLFIIGASNRPDL------DPALLRRFDKLLYVGVNADASLKALTRKFKLSEDVSLYSVA-----------KKCPSTFTGADMYALCADAWFQAAKRKVSKSDSGDMPTEEDDPDSVVVEYVDFIK. 944
54 -10.100[R] COG2842 Uncharacterized ATPase, putative transposase  ali follow..  15  78...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RQIFKTLEFAQIANCL--------ATVYGMSGVGKTKAIQEFAKSHANVSRSSLSEILYEIALELGISDAPRRKGTLTEGLLIVDEADHLPYEALEELRIMQEEAGIGLVLVVYTRMKGGISPSHEYARLWSRVAKNTSIQKTKKADTQAVAQAWGLE-----TDEEALKVMQSIT-----ETGGGLRILTQTYACR..................................... 277
55 -10.000[H] COG1239 Mg-chelatase subunit ChlI  ali follow..  10  2......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TAQTTAQPKARTLGELLQTPEYAGRKPFDGQRRLVQDEVRDNLTRKLRSGEELFPGVVGYDDTVIPQL--------VNALLARQNFILLGLRGQAKSRILRAITELL-------DPEVPVIDGVDMPLATPDVTVADLIGGIFAVNELADLSPKVQVALFNILQEGD-DVMLVFSANPEDYTARGKIVTPLKDRIGSEIRTPTDVQLGMDITAQEAVKEEGVVVPPFIAELIEDIAFQAREDGR-VSQRLPISLMELACANAERRSL............................ 337
56 -9.770[O] COG1219 ATP-dependent protease Clp, ATPase subunit  ali follow..  17  77.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................QYVIGQERAKKVLAVAVYNHYKRLNQRDKKDDSNILMIGPTGSGKTLLAETLARLLNV-------PFTIADATTLTEAGYDYDVEKAQMGIVYIDEIDKISRKSDQALLKLIEGDTRNILFICGGAFAGLERVIQNRPEFVGRLPVIATLDELDEAALMQILTE---------PKNALTKQYAKLFEMEGVDLEFRPDALKAVARKALERKGARGLRSILEGILLDTMQDVSKVVIDESVIDGS 406
57 -9.750[K] COG5164 Transcription elongation factor  ali follow..  10  2............................................................................................................................................................................................................................................................................................................................................................................................SDNSDTNVSMQDHDQQFADPVVVPQSTDTKDENTSDKDTVDSGNVTTTESTERAESTSNIPPLDGEEKEAKSEPQQPEDNAETAATEQVSSSNGPATDDAQATLNTDSSEANEIVKKEEGSDERKRPREEDTKNSDGDTKDEGDNKDEDDDEDDDDDDDDEDDDDEAPTKRRRQERNRDIEAEVSDDEDEDEDEEDSELVREGFITHGDDEDDEASAPGARRDDRLHRQLDQDLNKTSEEDAQRLAKELRERYGRSSSKQYRAAAQDGYVPQRFLLPSVDTAT-----GVRCRPGKEKELIRKLLKKKFNLDRAMGKKKLGRIYIEAPKQSVIEKFCNGVPD--IYISQKLLIPVQELPLLLKPNKSDKGDLAMVDQISENNLEVMLKIVPRLRPTFAHRAPPQLFNPTMALRLDQANLYKRD-EDYIDGYLYKSFRIQHVETKNIQPTVEELARFGSEGAVDLTSVSQSIKKAQAAKVTFQPGDRIEVLNGEQR.. 548
58 -9.740[DO] KOG4322 Anaphase-promoting complex (APC), subunit 5  ali follow..  18  538LNSIEGVYRKAVV--LQAQNQMSEAHKLLQKL--QKLKNISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILVAKCQVASAASYDLNEAKNYFAKVDCKERIRDVVYFQARLYHTLGKTQERNRCAMLFR.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 738
59 -9.650[U] KOG2376 Signal recognition particle, subunit Srp72  ali follow..  13  20.........FTSLHKHIKDTKYEEAVKVADQVLSIVPTDEDAIRCKVVALIKDDKFDDYLIKDLVCLKGLERESKTLLLEAQILNCLGKVDACVDVYQKLNKSGIKLTTTYQLAYNTACSENSNYVDAEQLLLTLTEGDYSDD-SVQLAYVQQVLGQTQESKSSYVDII.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 257
60 -9.650[R] COG5271 AAA ATPase containing von Willebrand factor type A (vWA) domain  ali follow..  11  865...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................FPVEEQEHYIITPFVQKNLLNIARACSTR--------MFPILIQGPTSSGKTSMIEYVAKKT-------GHKFVRINHEHTDLQEYIGTYVT-NGYWIVLDELNLAPTDVLEALNRLLDDNRPEFMLFATNPPGVYAGRKHLSRAFRNRFL-EIHFDDIPENELETILHKRCKIAPSYAAKIVFRELSLRRQTTRIFEQKNSFATLRDLFRFREAVGYQQLAENGYMLLAERARDQKDKLAVQE...... 1129
61 -9.550[L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase  ali follow..  10  24......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................QTVEQYIGQQHIGKPLRRALE----------AGHIHSMILWGPPGTGKTTLAEVAANYA-------NAEVERVSAVTSGVKEIRAAIEKAR-TILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPS-----FELNNALLSR--RVYKLTSLNQQEILQALHQAIAKVAAVFADNVLDRLAELVN--------GDARMSLNYLELLYDMARED.............................. 226
62 -9.510[R] COG4785 Lipoprotein NlpI, contains TPR repeats  ali follow..  12  36.PTLQQEVILARMEQILASRDFSQALAI-------RPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAEQKLDE--KQAKEVLKQHFEKSDKEQWGWNIVEFYSEQTLMERLKADATDNTTNFYLGKYLDSATALFKLAVANNVHNFVEHRYALLELSLLGQDQDDLAESDQQ............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 294
63 -9.470[O] KOG0739 AAA+-type ATPase  ali follow..  11  46........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EAHSDKAKESIRAKCVQYLDRAEKLKDYLRSKEKHGKKPVKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAV--KFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEAN------NSTFFSVSSSDLMSKWLGELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADRDSLMQPVRKVQSATHFKKVCGPSRTNPSMMIDDPGDKLLEPVVCMSDMLR. 409
64 -9.420[DO] KOG1173 Anaphase-promoting complex (APC), Cdc16 subunit  ali follow..  12  446RRYLSKATALDR-HSFANENEHEQAMAAYFKATQLMRGCHLPLLYIGVECGLTKNLELAEKFFLQAMNIAPLDVYVLHELGVIKYEYEFFDGAATIFQCTVDIVKQRAKSNFINLGHSLRKVHKYEEALYNFQYALLLKPQSPTTYSIGFIHALLGNLDPAIE-------------AFHKSLALN.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 638
65 -9.320[T] COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains  ali follow..  11  119.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DEALEQSAPATDDSWRNAIVTRSPLMLRLLEQARMV--------AQSDVSVLINGQSGTGKEIFA----QAIHNASPRSNKPFVAINCGALPEQLLESLFQAAEGGTLFLDEIGDMPAPLQVKLLRVLQERKVRPL-IISATHRDLPKAMARG-EFREDLYYRLNVVSLKTEDIPLLANHLLRQSAQRHKPFVRAFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVIS........................... 374
66 -9.230[F] COG1618 Predicted nucleotide kinase  ali follow..  11  5...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................GKEKTMLRIAVTGSPGVGKSTVVAKTAEKLAEKPGFKIGGIRTVNLDDLERIGANAVRNALACDLVVIDEIGPMELISVSAVEEVLESDKPVLAVLHHSSRHPLAQRFRKGFEV-------LTVDKGNRDELPEKITNRFLR............................................................................ 181
67 -9.140[TU] KOG3895 Synaptic vesicle protein Synapsin  ali follow..  9  295.TKFPSVLKAGHCHGGVAT------ARLENQSALQDAAGLVSGA--SHCYCTIEPYIDAK---------------------SVHIKIG------NNYKAFMRKSITGNWK----------QGSAMLEQITLTEKYK------SWVDEISELF---GGMEVC-----SVVVAKDGREYIISACD-RRQIADLVSGRMQNVCRPSMAQTGPGKLPSRSSVSSRAESPTDEGVAPTPPLPAGPRPAPMGGPPPIPERTSPAVGSIGRLSSRSSISEVPEEPSSSGPSTVGGEIANKKRGRTASETSSGSGPGSVPSSAGPGSGFSSSFLGKQFSFAGKGEGVISTQPTQRPSEEPPAIPTTASSAVRPESSVSVSDSRNTDTLTERAGAGYQPVTNYEQQERVNPFDKEPSKSGSAASIHTSSSSSISSSSISSRINRNGNAIQSPPPPAGPPPPPPTNVTAVGSNANSSSGYRNSFSSSLSKDKTSYGNYGSTTSVETITRMDTNTTNIGATATEAGEASGVTAITNISNSDGIVAPTTGTITTSVTTNDWRSAIGMRSASVYSAPAAVTTVLPGDTSGYDSNSIASQGEGLNNPSDLPSYTRPSYSRSESNASKHSDLDVIFGDSKTTPASYGNGKYTRAAGSISDADMIFGGPPSNYKTDRFGASKSMSMTSGGVGSGNG-GYKIYDSIQNAAFSDFSDSGSMSSIGSHTKRWSASKEE--------DDELDLK............................................................................................................................................... 986
68 -9.120[O] KOG0740 AAA+-type ATPase  ali follow..  10  348....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DGGEQNGGMQCKPYGAGPTEPAHPVDERLKNLEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIV--LRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQS-------GATFFSISASSLTSKWVGEG-EKMV-AVIFIDEIDSLSRRIKTEFLVQLDTSSEDRILVVTNRPQEIDE------AARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGAD-------MTQLCRGASLGPIRSLQTADI-----ATITPDQVRPIAYIDFEN. 646
69 -9.100[T] KOG4162 Predicted calmodulin-binding protein  ali follow..  13  687.............QALSEAASSLSSFTQRPGPRRPWMLQIEIWLLLADVYLRIDQPNEALNCIHEASQIYPLSHQIMFMRGQVHVYLEQWFDAKQCFLNAVAANPNHTEALRALGEAHLVLG-EPRLAEKMLKDAAKLDCPKIW-FALGKVMEILGDFHASAD--------------FATSLQLE.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 845
70 -9.100[R] KOG2170 ATPase of the AAA+ superfamily  ali follow..  10  58........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................HEPDVNFNYHTLDADIANLLFGQHLVKDVVVNSIKSHWYNENPRKP-----LSFHGYTGSGKNYVAEIIANNTFRLGLRSKNKLEEYQVE---RNRILTTVQKCQRSIFIFDEADKLPEQLLGAIKPFLDDFRRSIFILLSNRLEAFERELMNELISNHLIDHFVPFLPLQREHVRSCVGAYLRKRGLVSNVDFVERVLNSLQYFPESSKAFSSSGCKRVTDLEMAKIRPL.............................. 346
71 -9.030[TZ] KOG4035 Coeffector of mDia Rho GTPase, regulates actin polymerization and cell adhesion turnover  ali follow..  7  1.........................................................................................MLKA--LY-DFQAVYPKT-----ISFD---------GEYFILYQTSAR---QRNW-WQVVSMKGNIG---------------FVPSNYVMKI-----------KVEHDFLISFLNSSIESLEKCTDHEINGIMSKDELLDRLREKKHTMERLYAESSERDGDSSLSYSHSYSDKGSHRHSHPHPTQSQTQLHSQHRQHSPPPSGGSVGSQRLDMSKKSMSSPAVGSSCGLPQNQGMIESPSMGSMQFQGSSCTIQTPQQQQPLPAPPAPAPSPSAASATPTAASTSKAATGGDVAQDNSITSEPSETTTTTTTTSEDVVTTYKETSQMSTSQQHKPQNGSTASASISASASASALRSNGGNGKANGSATALHQELQQEEADSAPDKSDDASAVQSDDGCPANGDSADNSQALDSIDSPSHRQRGLSLGRIEEGATGGGQLKVESSDVYQIVDALRRNTNLSFDLSCEALRVVLTSLEQLYNGAINPYLEAVAVHVTGKVATPKELLGITHDAKRLQYLFAQLADCKNDTEQRTWMLYEDEEDIIQFL-------EELVEILINADESISCYEMSCDQYQMFI----ETRWSIKRLLLKTFTAACHLDYIIVDILLTSVLPLEIVEDMKDRFKQLVKMLNHQDYLGVHFASFLLEIVEGNNPELILAFNQQ-EKLLLLLNREDDFIDIFSHPDTAGMFYTNDIKVLIDIVVRQAGSTTRPCYLELCRRILRNTNYQEHQHRKHDLMKIFTRIFCEET--------------ECSASDQQLVRENEFPQ. 797
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Rychlewski L, Zhang B, Godzik A. Fold prediction by a hierarchy of sequence, threading, and modeling methods. Protein Sci. 1998 Jun;7(6):1431-40.