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Query: sp|O14791|APOL1_HUMAN(removed signalp:1-27) Apolipoprotein L1 OS=Homo sapiens GN=APOL1 PE=1 SV=5, from H.sapiens

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst EEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTMDPESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEEKLNILNNNYKILQADQELLast
1 -8.800[U] COG0811 Biopolymer transport proteins  ali follow..  10  106........................................................................................................................IKGTMRAMNL--AMNREIESLENRVPFLATVASVSPYIGLFGTVWGIMHA-GAKQATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLSLRVNAIEQDYGNFIDEFTTILHR.......................................................................................................................................... 220
2 -7.190[S] COG5613 Uncharacterized conserved protein  ali follow..  10  126....................................................................................................................IADIQRLHEQNMKKIEENQEKIKETEENAKQVKKSGIASKIFGWLSAIASVIV-----GAIMVAS----GVGAVAGAMMVASGVIGMANMAVKQAAEDGLISQ--EAMKILGPILTEVALTVVSTVMTFGGSALKCLANIGAKLGANTASLVAKGAEFSAKVAQISTGISNTVGSAVTKLGGSFAGLTMSHAIRTGSQATQVAVGV--ITQTINNKKQADLQHNNADLALNKADMAALQSIIDRLKEELSHLSE. 371
3 -6.500[P] COG4985 ABC-type phosphate transport system, auxiliary component  ali follow..  10  14.....................................................................................................................................................LTGGAVSV--SLIAVLGLLLVIGWRGLTYFWPAPLLQWQTPDGKTVVGQLYARESVPVSHLKEMNLPLPEKVQAAGLATRLNIKVANR-SDFIALLEFETEFKGAPQGWAVIERSRGGQLFGKPLRFDSTTGELDLPLERHLRQALLEAETIRDQVDKMVEQQVRVISSQLERLRLEKRRKQLNNQLSDEFLQHYVLSKSRLEKELAQVQTELDALRAPLE. 235
4 -6.310[E] COG3404 Methenyl tetrahydrofolate cyclohydrolase  ali follow..  8  1..................................................................................................................................MHKFKNFVPFNVHMEGIEDFLEKLAS-------------SPAPGGGAASAFVSIVGGSLISMVSQLTIG--------------KKNYAQYDAEMKGILERERQIEKDLRSLIDEDERAFNAIMEALKMPKDTESQKKVREEKLQSALRTGIDVPWKIARKAYDLLANAVTDAGSAALFLQAAIKAALYNVKI--------NLKMVKDEDYVADQRMKINVFLENTDDLERIRKKVEE.... 215
5 -6.220[S] COG5412 Phage-related protein  ali follow..  10  1................................................................................................MADYTLTAKLTADPSGFRAGFQKAQESLANLQSRVNQTGKRVQSI--GKSISDLGSKLTRNITVPAVGAATALTSITLVKGFGIDSARAKLKGLGHDAEAIDSIMDSALADEAATTAANAVAAGIPPGKELTRYLSLTADTAAIAGTSLGEIGAILNKVTTSGRAYNSELQMLSDRGLPVYQWLAEEANTTADAIFDMASKGEISTDMLLNAIEKNIGGAA--------KIMGEESFSAAIANIGADIARIGANFLDAGGKAGGFFSTVKPLLT. 277
6 -5.670[UD] KOG2218 ER to golgi transport protein/RAD50-interacting protein 1  ali follow..  9  2...............................................................................................................................................................GSECVAGLSQTPATLAAGEMLPAGEIGASPAAPCCSESGDERKNLEEKSDINVTVLIGSKQVSEGTDNGDLPSYVSAFIEKEVGNDLKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQETHLFSAINSHLLTA-WMDDLGTMISQIEEIERHLA-KWISQIEELSDNIQQYLNNVPEAASTLVSMAEL 226
7 -5.640[S] COG3610 Uncharacterized conserved protein  ali follow..  15  67..................................................................................................................................VAILSHFFAKHKKMPITIFNVPGIVPLVPGGLAVRNFVLGDYTEAIGFSVQVTVVAGAIAAGLM-LSEVFNHSIRAFRGRKE............................................................................................................................................................... 150
8 -5.550[P] KOG1485 Mitochondrial Fe2+ transporter MMT1 and related transporters (cation diffusion facilitator superfamily)  ali follow..  10  62..............................................................................................RTPKKERKVSEYYKQQEKLLEGFNEMETINETGFVSGAPTEEELKKLAKSERLAVHISNAANLV---LFVAKVYASVESRSMAVIASTL-------DSLLDLLSGFILWFTANAMRTPNNFRYPIGKRRMQPVGIIVFASVESTRLLVSKNGSHMSSTEEKWMIGIMASATVVKFLLMLYCRSFQNEIVRAYAQDHLFDVITNSVGLATAVLAVSGAILIALYTISTWARTVLENVHIGRSAPPDFLAKLTFLIWNHHEKIKHIDTV.......... 338
9 -5.520[S] KOG4096 Uncharacterized conserved protein  ali follow..  12  19.........................................................................................................................................FTKIRMGLMMGAMIGGATGILLGGFMGFRAGMRGKDLLLQTGKTVAQSG-GSFGVFMGVAQGL........................................................................................................................................................................... 80
10 -5.450[Z] KOG0980 Actin-binding protein SLA2/Huntingtin-interacting protein Hip1  ali follow..  12  654.........................................................................................................................KLLRQDIQTLNSLMISLPLQTDIDK-QEMRRMDDAIRRAVQEIEAIQRRARESSDGIRLEVNESILANCQALMSVIMQLVEIVAAGKAGGSPAEFYKRNHQWTEGLLSAAKAVGVAARVLVESADGVVTGKGKFEHLIVAAQE------AASTAQLFVSSRVKADKDSSKLDALSVAAKAVNQNTAVVAAVKNGQTTLNDEGSLDFSYLSLHAAKKEEMESQVKML--ELEQSLNQERAKLAALRKQH.. 910
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 9 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Jaroszewski L, Li W, Godzik A. A segment alignment approach to protein comparison. Bioinformatics. 2003 Apr 12;19(6):742-9.