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Query: sp|P04424|ARLY_HUMAN Argininosuccinate lyase OS=Homo sapiens GN=ASL PE=1 SV=4, from H.sapiens

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQALast
1 -134.000IDP04429 gene: argH-2; argininosuccinate lyase [Bacillus anthracis str. `Ames Ancestor`] GBAA4879 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  43  2.....SKLWGGRFTEEAEAWVEEFGASISFDQQLVNQDINGSIAHVTMLAKQGIVTKEEAEKIKIGLQYLLEEAKQNKLHFSVEAEDIHLNIEKMLMEKIGEVGGKLHTGRSRNDQVATDMHLYLKEKVEHIIKAIKQLQTVLVHQAENNIETIMPGYTHLQRAQPISFAHHILAYFWMLERDVNRYEDSLKRINISPLGAGALAGTTFPIDREYSAELLGFNGIYENSLDAVSDRDFILEFLSNSSMLMMHLSRFCEELILWSSQEFQFIEMSDQYATGSSIMPQKKNPDMAELIRGKTGRVYGNLFSLLTVMKGLPLAYNKDLQEDKEGMFDTVKTVEGCLHIMAGMLETMTVNKEKMGQAVTQDFSATEIADYLANKGLPFRQAHEIVGKLVLHCTQKGIYLIDVPLATYKEMSALFEEDLYEVLSPYAAVKRRNSAGGTGFEQIEKALEKAKGLTKEAIK 461
2 -125.000IDP90621 gene: argH; argininosuccinate lyase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0931c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  42  2....KNEMWSGRFSGASDELLKEFNASLNVDKTLFNEDIQGSIAHATMLESCGILKKEELDAIIKGLEQVRSEIEQGKFIFDIKDEDIHMAVEKRLSEIIGEIGGRLHTARSRNDQVATDFKLFVKKSHIELIKLLKELIQTMLEHAKVHKKTIMPSFTHLQHAQPVSFSFYILAYAFMLMRDIKRLQNSLELADFSPLGSCACAGTSYAINRELSAKILGFKDIMPNAMDGVSDRDFALDLLYDIAVIFTHTSRLCEEMILFSSSEFSFITISDSFSTGSSIMPQKKNPDVCELIRGKTGRVYGNLISLLTIMKALPLAYNKDMQEDKEGIFDSVKTAKDSLIILNAMLKEIQINKENMLNACKGHLLATDLADYLVEKNIPFRKAHFIVGNVVAQAEAQGIDISEI--KDLSKIDPVFDEKAMELLNFEFSLNSKQSEGSSSIASVEKQIQILEGFIQN... 459
3 -124.000IDP00537 gene: argH; argininosuccinate lyase YPO3924 [Yersinia pestis CO92]  ali follow..  45  2......ALWGGRFSQAADQRFKQFNDSLRFDYRLAEQDIIGSVAWSKALVTVGVLNADEQQQLEQALSVLLEEVQANPHAIASDAEDIHSWVETKLIDKVGDLGKKLHTGRSRNDQVATDLKLWCKFQITELQTAVQQLQQALVMTAEANQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLSRDESRLQDTLKRLDVSPLGCGALAGTAYAIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDASIGMVHLSRFAEDLIFFNSGEAAFVDLSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMTMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCKEAAEGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKALEALALSDLQQFSSVIGDDVYPILALQSCLDKRVAKGGVSPQQVASAIAEAKARL..... 456
4 -117.000IDP02396 gene: argH-1; argininosuccinate lyase [Bacillus anthracis str. `Ames Ancestor`] GBAA3604 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  24  1MKQSKIKSEGADFPGKTYVDCVLQHVFDFQRNYLLKDMFQVHKAHIVMLTEENLMKKEEAKFILHALKKVEEI-PEEQLLYTEQHEDLFFLVEHLISQEAKDFVSNMHIGRSRNDMGVTMYRMSLRRYVLRLMEHHLLLQESILQLAADHKETIMPAYTHTQPAQPTTFGHYTLAIYDTMQRDLERMKKTYKLLNQSPMGAAALSTTSFPIKRERVADLLGFTNVIENSYDAVAGADYLLEVSSLLMIMMTNTSRWIHDFLLLATKEYDGIAVARPYVQISSIMPQKRNPVSIEHARAITSSAPGEAFTVFQMIHNTPFGEIVDTEDDLQPLYKGIEKAIRVFCILNAVIRTMKVEEDTLKRRSYHAITITDFADVLTNYGIPFRHAHHAASVIANMSLEQKKELHELCFKDVNIYLQLLEKEWEEIISPEAFIQKRNVYGGPSKKEMERMINNRKELFRKEEE 476
5 -88.100IDP04633 gene: purB; adenylosuccinate lyase [Francisella tularensis subsp. tularensis SCHU S4] FTT0015 [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  15  3..........KRYDVA--------ISKIWADENKYAKMLEVELAILEALED-RMVPKGTAAEIRARAQIRPERVDEIE---KVTKHDIIAFCTSIAEQFTAETGKFFHFGVTSSDIIDSALSLQIRDSMSYVIKDLEALCDSLLTKAEETKEIITMGRSHGMFAEPMSFGQKFLGAYVEFKRRLKDLKDFQKDGLTVQFSGAVGNYCILTEDEKKAADILGLP--VEEVSTQVIPRDRIAKLISIHGLIASAIERLAVEIRHLHRSDVFEVEGFSKGQKGSSTMPHKKNPISTENLTGMARMLRSHVSIALENCVLWHERDISHSSAERFYLPDNFGIMVYALRRMKNTIDNLVVQRDIIEDRVRAYLSSFYLHFLVANTPFMREDCYKIVQQVAFDLKQGESFSKKLQKVMHDEHNILDIPEMDFEGIKKTYL-------KEIDHVFDRSVKA.......... 432
6 -87.600IDP04255 gene: purB; adenylosuccinate lyase [Clostridium perfringens ATCC 13124] CPF_1922 [Clostridium perfringens ATCC 13124]  ali follow..  15  1MKNLYSTPLNSRYASK--------MSYIFSDDMKFSTWRKLWVALAEGEKELGLNITDEQIEELKSHIS-DINYEEAIKKEKEVRHDVMSHVYA-YGLQCPSAKGIIHLGATSCYVGDNTDVIIMRDALLLIKKKIVAVLNNLKRFALEYKDMPTLGFTHFQPAQLTTVGKRATLWMQDLVMDMENIDFLLSTLKLRGVKGTTGTQASFEGDEEKVKALDKIVKKSFGVTGQTYPRKLDSIILNTLSEIAQSAYKFSNDLRLLQSMKE-IEEPFEKNQIGSSAMAYKRNPMRSERMGALARYVIVDALNPAITASTQWERTLDDSANKRIAVAEAFLALDGVLNLYINIAENMVVYDKVIEAHVNPFMATENIMMESVKKGGDRQELHERIRVHSMDAAQRVKGEDLIERIINDPSFNLSKEEIIAIIDPVKFV-------GRAPSQVVEFIDEYVNPIIEANK 465
7 -74.100IDP02640 gene: aspA; aspartate ammonia-lyase [Bacillus anthracis str. `Ames Ancestor`] GBAA0609 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  18  17KEVPSIAYYGVQTLRAVEAIVKKAAALANMDTGYLAKDIGHEIAEAAQEIVDGKFHDQFIVDPIQGGAGTSINMNTNEVIANRALERMGYEKGEYA---KISPNTHVNMAQSTNDAFPTGIHIATLMRLEELLITMEELHAAFRAKAKEFDHVIKMGRTHLQDAVPIRLGQEFEAYSRVLARDIKRIKQSRQHLYEVNMGATA-VGTGLNANPTYLRTFSGFPVGAEHLVDATQNTDAYTEVSAALKVCMMNMSKIANDLRIMASGPRVGLAEIQARQPGSSIMPGKVNPVMAEVINQVAFQVIGNDHTICLASEAGQLELNVMEPVLVFNLIQSISIMNNGFRVFRECIKGITANEELLKQYVEKSV--------GIITAVNPHIGYEAASRIAREAIETGKSVRELCLEH----GVLTEEELDIILDPFEMTHPEIAGASLLKDK................. 475
8 -72.600IDP92060 adenylosuccinate lyase, putative [Toxoplasma gondii ME49] TGME49_063190 [Toxoplasma gondii ME49]  ali follow..  13  29.........DGRYAKKVAGLKAAVSEFLACLATNARVQRQSAADASESPAPFPSLSEEGKAALRQMGRFSMDDVRRVKEVEKTANHDLKAVEYVLKGKLTMPLAALTHFGCTSEDVNNLSWALCFKEATEQLLPAVDDLAASLHMRAVEFAEVPMLSLTHGQPATPSTFGKEIANFEWRVKNAIKRVRDVEFRGKYNGAVGCFNALVVADAKARDFVESLGLT--YQPYSTQIEQHDWIAELCDALARLNSILLDFSRDMWLYISRDVLKLRVV-AGEVGSSTMPHKVNPIDFENAEGNLELANALLRFLSTKLPVSRMQRDLSDSTVLRNVGVAFGHCLVAYESAKKGLDRVDVNSEKMLKELDENWAVLGEPVQTLLRKRGVRNAYEKLKSATRGQDIDKERMQDI-VETCSKDLLPEDLEILRSLTPATYT-------GLAPELAKKVGETMEEEAAKKQK 497
9 -71.500IDP02169 gene: fumC; fumarate hydratase [Francisella tularensis subsp. tularensis SCHU S4] FTT0306 [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  16  12IEVDNDKYWGAQTQRSIEHF----IGSDLMPIEVIKALAIIKKAAAITNHQLGILARTKKEIIIKVADEIIAGELDEHFPLRQSNMNVNEVISNRAIELLGHPNDDVNMSQSSNDTFPSAMYIATALEINRLLPALEYMQQQLADKAKQWDDIVKIGRTHMQDAVPLTLGQEFSGYAALLENNIQRIKDTLKYVYQLALGGTAVGTGLNAPDGKYIATITSLAVSATNKFEVQGSHDALVAVMGQLKTLANSLFKIANDIRLLSCGPRAGFHE-PENEPGSSIMPGKVNPTQCEAMAMVAAQVIGYDVAVGIGGSAGYLEMNVYKPLIIFNIIQSIKIISDSCNFTKYLLEGMKPNHDKIEFYLKNSLMAAKLAHYAEQKNISLAEANQELKFLSKEEFDKVVDPYKMT....................................................... 458
10 -69.500IDP02192 gene: aspA; aspartate ammonia-lyase [Yersinia pestis CO92] YPO0348 [Yersinia pestis CO92]  ali follow..  15  15REVPAEAYYGVHTLRAIE-NFYISNSKISDVPEFVRGMVMVKKAAAMANKELHTIPRKIADIIIQACDEVLDKGKNMNTNEVLANIGLELMGHQKGEYQYLNPNDHLNKCQSTNDAYPTGFRIAVYASILKLIDAINQLGEGFGRKSKEFEKILKMGRTQLQDAVPMTLGQEFRAFQVLLNEETKNLQRTAELLLEVNLGATAIGTALNTPEGQKLAEISGLAVPAEDLIEATSDCGAYVMVHSALKRLAVKMSKICNDLRLLSSGPRTGLNEINELQAGSSIMPAKVNPVIPEVVNQVCFKVIGNDTCITMAAEAGQLQLNLMEPVIGQAMFESIHILTNACNLLEKCINGITANKEVCERYVFNSGIVTYLNPFIGHNGDIVGKICAETGKNVREVVLERGLLTEAELDDI---------SVENLMHPAYKAKRYTD......................... 474
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Harder T, Kolodny R, Sitbon E, Li Z, Godzik A. Using an alignment of fragment strings for comparing protein structures. Bioinformatics. 2007 Jan 15;23(2):e219-24.