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Query: sp|Q5VV42|CDKAL_HUMAN CDK5 regulatory subunit-associated protein 1-like 1 OS=Homo sapiens GN=CDKAL1 PE=1 SV=1, from H.sapiens

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAYGYKITENASDADLWLLNSCTVKNPAEDHFRNSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQIDRVVEVVEETIKGHSVRLLGQKKDNGRRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGNLASYPIDELVDRAKQSFQEGVCEIWLTSEDTGAYGRDIGTNLPTLLWKLVEVIPEGAMLRLGMTNPPYILEHLEEMAKILNHPRVYAFLHIPVQSASDSVLMEMKREYCVADFKRVVDFLKEKVPGITIATDIICGFPGETDQDFQETVKLVEEYKFPSLFINQFYPRPGTPAAKMEQVPAQVKKQRTKDLSRVFHSYSPYDHKIGERQQVLVTEESFDSKFYVAHNQFYEQVLVPKNPAFMGKMVEVDIYESGKHFMKGQPVSDAKVYTPSISKPLAKGEVSGLTKDFRNGLGNQLSSGSHTSAASQCDSASSRMVLPMPRLHQDCALRMSVGLALLGLLFAFFVKVYNLast
1 -96.700IDP06049 (dimethylallyl)adenosine tRNA methylthiotransferase [Helicobacter pylori J99] NP_222975 [Helicobacter pylori J99]  ali follow..  25  1...............................................................MKVYIETMGCAMNSRDSEHLLSELSKLDYKETSDPKMADLILINTCSVREKPERKLFSEIGQFKKPNAKIGVCGCTASHMGADIAPSVSFVLGARNVSKISQVIHKEKAVEVAIDYDESAYAFE---------FFEKKAQIRSLLNISIGCDKKCAYCIVPHTRGKEISIPMDLILKEAEKLANNGTKELMLLGQNVNNYGVRFKVGFSDLLDKL-SEIQGIERIRFTSPHPLHMNDAFLER--FAQNPKVCKSIHMPLQSGSSAVLKMMRRGYSKEWFLNRVERLKALVPEVGISTDIIVGFPNESDKDFEDTMEVLEKVRFDTLYSFIYSPRPFTEAGAWERVPLEISSLRLERLQNRHKEILEEKLEVGKTHVVLVENRREMDVGFEGRSDTGKFIEVTCKEKKPGELVRVEIISHSKGRLMATTKGN..................................................................................... 437
2 -16.500IDP02138 coproporphyrinogen III oxidase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0580c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  13  4..............................................................................................................................................................................................................YIHI---CESKCNYCFTSLKKNDYEKAYFKALKEDIVFQLKQ-IKTLFIGGGTPSCVNAY---NYEDIFKILYPLLDKNVEISC-EANPNSATLNWLKNMKNLGVNR----ISFGVQSFHPKKLHFLGRIHNQEMIIKTLENANKV----NINLDLIYDTKLDNKKMLEFELLHLKQIKDLITHLSAYN-ESNTAFAKKEH-FKKNAPNLMKFFIKQLLELDFFQYEISN............................................................................................................................................... 231
3 -15.900IDP02776 gene: lipA; lipoic acid synthetase [Coxiella burnetii RSA 493] CBU_1266 [Coxiella burnetii RSA 493]  ali follow..  11  75.........................................................................................................................................................................................................GHGTATFMIMGDCTRRCSFC--DVGHGRPDPLDPEEPVNLANTVSIMSLRYVVITSVDRDDLRDGGAQHYAQCINAV-REKNPGIKVEVLVPDFRGRMEKALDQLAQGLPDVFNHNIET-----APRLYKQARPGADYPWSLALLQTFKKRFPGIPTKSGMMLGL-GETREEVEMVMRDLRQHEVDRLTLGQYLQPTRYHMPVDRYVTPQEFQELGELAKKLGFSNVASGPLV................................................................................................................................................. 299
4 -15.700IDP01993 gene: hemN; coproporphyrinogen III oxidase [Listeria monocytogenes EGD-e] lmo1476 [Listeria monocytogenes EGD-e]  ali follow..  16  2.................................................................................................................................................................................................INTNLSSNESSAVYIHI---CEHICYYC---FLEGQPVDEYVDLLIKEMEKGPIAPVDTVFVGGGTPTTLNEA---QIARLCTAIHNTLPLKKDIEFSFANPGDLSLSKLQAMQDHGVNR----ISMGVQSFNNELLKKIGRIHTVKDVYQSVENMRKI----NVSIDLIFSLPGQTEADFQDTLKQALDLDLPHYSAYSLIIEPKTIKGKLFLPGQDAEANMYDLLLNEMEKHGRKQYEISN............................................................................................................................................... 248
5 -15.600IDP92104 lipoic acid synthase [Toxoplasma gondii ME49] TGME49_026400 [Toxoplasma gondii ME49]  ali follow..  11  268...........................................................................................................................................................................................................TATLILLGDTCTRGCRFCAIKTSSKPPPPDPPEKVADAVAKWDIDYVVMTSVDRDDMPDGGAGHFARTVQLVKKAKPSMLIECLVSDFQGME--------ESVRTLAQSGLDVYAH--IETVRRLTPYVRDKRAKYDQSLRVLHLAKQFNPSLFTKSSIMVGL-GETSEEVVRTLRDLRDHDVDVVTLGQYLRPTKQQLGVVEYVTPETFKKYQDIAEEMGFKYVASGPLV--------------------------RSSYKAGEYYMKHLIDDARKHGRRETVKQVKLEADVGTLKGTTTTFQVNEKEA.................................................................. 543
6 -15.600IDP93864 radical SAM family enzyme [Yersinia enterocolitica subsp. palearctica Y11] YP_006005839 [Yersinia enterocolitica subsp. palearctica Y11]  ali follow..  14  2......................................................................................................................................................................................................LKLPPLSLYIHI---CVQKCPYCSHALKGDVPHQEYVEHLLADLDLVSGREISTIFIGGGTPSLLSAE---AMQQLLDGVRARLPLAIDAEITMANPGAVEADRFSGYQRAGINR----ISIGVQSFSAEKLTRLGRIHGPYEAKRAAELATSL----SFNLDLMHGLPDQSLEEALDDLRQAIALNPPHLSWYQLTIEPNTGSRPPTLPDDDALWDIFQQGHQLLSAAGYQQYETSA............................................................................................................................................... 240
7 -15.400IDP02195 gene: hemN; oxygen-independent coproporphyrinogen III oxidase [Francisella tularensis subsp. tularensis SCHU S4] FTT0084c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  13  5........................................................................................................................................................................................................NKQIGIYIHF---CVRKCPYCDFNSHPIKDDSYLSEQYYQKLIADFDTHLDDLQAREVISIFIGGGTPSYLDKVLQHITKNTKISINCEITLMNPGTVERGSILSYQNIGINR----ISLGVQSFQDDKLKILGRIHNCENVYTTIDEIKNS----NFNIDIMHGLPNQSFDDGIFDITQAIAMQPTHISWYQLTIEPNTLAKRPKFPDEEILESIEIAGKEALAHAGFKQYEVSA............................................................................................................................................... 242
8 -15.400IDP02134 oxygen-independent coproporphyrinogen III oxidase, putative [Coxiella burnetii RSA 493] CBU_0597 [Coxiella burnetii RSA 493]  ali follow..  13  1......................................................................................................................................................................................................MSAIPLSFYIHM---CIRKCPYCSHALHQDLPEEAYINALINELRLIEKRPIHTIFIGGGTPSLFSQT---AYQKLFEEIKKQCLLKKEVEITLANPGSVEQTKFRGYREIGINR----LSIGVQSFQNDKLKVLGRIHSAEEAKQAINIAKQA----NINVDLMFGLPDQKVNEALDDLQTALDLEPTHLSWYQLTLEPNTFFYKPALPTDDYIWEIQSKGRKLLRRDGFAHYEVSA............................................................................................................................................... 239
9 -14.700IDP02554 gene: lipA; lipoyl synthase [Francisella tularensis subsp. tularensis SCHU S4] FTT0653 [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  13  86..........................................................................................................................................................................................................HGTATIMLMGSCTRACKFCSVD-TGNPKGWLDKDEPMNAAESVKLMGLEYVVLTSVDRDDLEDGGAGHYAATITAIKNLDEN---IKVEALTPDFAGIN--ENIDKIINTKVDVIAQ--IETVERLTHPVRDPRAGYWQTLNFLKYVKQKSPNVLTKTSIMVGL-GETDEEIYKTMDDARSVGVDIITLGQYMQPTKHHLSVERFVTP----QQFEEYRKVGLEKGF---------LEVASGPMVRSSYRADR............................................................................................................................ 318
10 -14.000IDP05210 gene: hemN; oxygen-independent coproporphyrinogen III oxidase [Clostridium difficile 630] CD2464 [Peptoclostridium difficile 630]  ali follow..  15  2.......................................................................................................................................................................................................................KKCKYCDFNSYKMDIDSKKIEDLKIEMELYSNK-ITSIFVGGGTPSILTSD---EIREVFISIKEMFDIDENAEITICNPGTLTLEKLKTMKEIGINR----LSIGLQAIQEKHLNFIGRIHTYEEFEKNYKDALSV----NINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTESNKFELIDENVDIEMYEYTINYLKSKGYNQYEISN............................................................................................................................................... 242
11 -13.900IDP04048 biotin synthase [Vibrio cholerae O1 biovar eltor str. N16961] VC1112 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  16  42...........................................................................................................................................................................................................VSTLLSIKTGCPEDCKYCPQSAHYRTDVDKEVERVLDAAQKAKNSGSTRFCMGAAWKNPKERDM-----PLLKEMIRGVKDMG-LETCMTLGMLTPDQAQQLAQAGLDYYNHN------LDTSPEFYGNIITTRTYQDRLDTLSHVRDA--GMKICSGGIIGMGESTNDRAGLLVELANPTHPESVPINMLVKVKGTPLEQVDDVEP----FDFVRLIAVARIMMPKSAVRLSAGREKMNEQMQALCFMAGANS.......................................................................................................................... 283
12 -13.700IDP02046 gene: bioB; biotin synthase [Coxiella burnetii RSA 493] CBU_1007 [Coxiella burnetii RSA 493]  ali follow..  16  41...........................................................................................................................................................................................................LCTLSSIKTGCPEDCAYCPQSGHYKTDVERNLEAVLEQAKVAKENGARRFCMGAAWRSPPKRE----LPKVLEMIKSVKALGLETCVTL----MLDQEQALQLKEAGLDFYNHNLDT-----SPEFYKKIITTRTYQDRMETLKNVRNA--GINVCCGGILGMGESRADRIQLLLELYQPEPPTSIPINQLIPIKGTPLENTKAIDP----FEFIKTIAITRLLFPTSVIRLSAGREAMSDELQAWCFMAGANS.......................................................................................................................... 282
13 -13.300IDP04719 gene: bioB; biotin synthase [Yersinia pestis CO92] YPO1151 [Yersinia pestis CO92]  ali follow..  16  42...........................................................................................................................................................................................................VSTLLSIKTGCPEDCKYCPQSSRYKTGLESQVEQVLESAKKAKAAGSTRFCMGAAWKNPHERD----MPYLAKMVEGVKALGMETCMTL----SLSKQQAHRLADAGLDYYNHNLDT-----SPEFYGSIITTRSYQERLDTLNEVRDA--GIKVCSGGIVGL-GETVRDRAGLLVQLANLP-ESVPINMLVKVKGTPLENNAEVDA----FEFIRTIAVARIMMPSSYVRLSAGREQMNEQTQAMCFMAGAN........................................................................................................................... 282
14 -12.600IDP01958 gene: bioB; biotin synthase [Francisella tularensis subsp. tularensis SCHU S4] FTT0937c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  16  35...........................................................................................................................................................................................................LCSLKSIKTGCPEDCKYCPQSGHYNTSIEKDKDSILAEAKNAKDAGSKRFCMGAAWKHIPKKD----FDQVAEIITEVKNLGLETCVTL----SINADEATKLKQAGLDYYNHNLDT-----SREFYPEIITTRKFEERIETIRNVANA--DINVCCGGILGMGESLDDRFNLLLELLQPAAPKSIPINTLIPIKGTPLGDKYTNAQIDSFELVRFIA.............................................................................................................................................................. 244
15 -10.600IDP91785 gene: cfr; Cfr [Staphylococcus aureus] ABQ00063 [Staphylococcus aureus]  ali follow..  12  96.....................................................................................................................................................................................................KYKAGWESFCISSQCGCNFGCKFCAT--DIGLKKNLTVDEITDQVLYFHLLGIDSISFMGMGEALANRQVFDALDSFTDPNLFAL-SPRRLSISTI----IIPSIKKITQEYPQVNLTFSLHSPYSEERSKLMP-INDRYPIDEVMNILDEHIRLTSRKVYIAYIMLPGVNDSLEHANEVVSLLKSRYKSHVNLIRYNPTISAPEM---GEANEGQVEAFYKVLKSAGIHVTIRSQFGIDIDA........................................................................................................................................... 336
16 -10.200IDP04337 gene: splB; spore photoproduct lyase [Clostridium perfringens ATCC 13124] CPF_0720 [Clostridium perfringens ATCC 13124]  ali follow..  10  83...............................................................................................................................................................................................................LPLLSGCVGNCQYC---YLNTNLGDKPVEDILNQAQKYIDERKPNIFEGSATSDPIPVE---PYTNSLKIAIEFFANNDFARFRFVTKYTDVDSLLGLNHNGK-------TEVRFTINTDFVINNYERR-SLCERINASVKIAKANYPLGFIIAPVFIYEGWKEDYENLLKDLKEKLPRDLQHKLTFEVISHRYTTRAKNIIMDIFPDNKLPMDDEKRTFKYGQFGYGK............................................................................................................................................... 308
17 -9.610IDP02218 gene: narA-1; molybdenum cofactor biosynthesis protein A [Bacillus anthracis str. `Ames Ancestor`] GBAA2133 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  15  18...............................................................................................................................................................................................................ISVIDRCNFRCTYCMPAEVFGEECLLTFDEIERLARLFISMGVNKIRLTGGE-------LRKDLPKLIARL-AKLEGLKDIGL-TTNGIHLAKQAKALKEA------LKRVNISLDAIEDRVFQKINGRHVSTKVLKGIEAAKEAGLEVKVNMVVKKGM---NDSQILPMAQYFKEQEIQLRFIEFMDVGSTNGWNFEQVVTKEQLIEKINRVYPIEPVKPRYFGEVAKLYRY........................................................................................................................................... 243
18 -9.390IDP95167 pyrroloquinoline quinone biosynthesis protein PqqE [Klebsiella pneumoniae subsp. pneumoniae MGH 78578] YP_001335473 [Klebsiella pneumoniae subsp. pneumoniae MGH 78578]  ali follow..  9........................................................................................................................................................................................................NPPLWLLAELTYRCPLQCPYCSNPLDFARQDKETTEQWIEVFRQARAMGSVQLGFSG------GEPL---TRKDLPELIRAARDLGFYTNLITSGIGLTESKLDAFSEAG----LDHIQISFQASDEVLNAALAG--NKKAFQQKLTMAK-AVKARDYPMVLNFVLHRHNIDQLDKIIELCIELEADDVELATCQF-WAFLNREGLLPTREQIARAEQVVADYRQKMAASGNLTNLLFVTPDYYEERPKGCMGGWGSIFLSVTPEGTPVAFPSVLEQSLESI................................................................................................. 286
19 -9.340IDP00488 putative heme-binding protein YPO1496 [Yersinia pestis CO92]  ali follow..  11  37....................................................................................................................................................................YLIGKIPANK--ILDADELEIYHNERTKKILAKAIKARKLVIVLKATRLCNLRCTYCHSEGPNQTILFSTLIHIVRQILAIPNVNRFEFVWHGGEVTLLKPAFFKKLIWLQEQFKRP----QYITNTQSNIVNISDEWLIFIKGIG-------MNVGISLDGIPAVNDKRRVDTSDRIAKGIKKLQKYDILYGALIVV----REVYQTDMREMLDYFILIELNGIEFLNIVPDNRLTAGEDIGNNFISYAEFIKFLSALFVIWIKGYAIFEDFISVLEHPEKKLSACYWSGNCSQEIITLEPN----GDVSPCDKYRGDAGSIYGSLLKTD.................................................................................... 362

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Sikora S, Godzik A. Combination of multiple alignment analysis and surface mapping paves a way for a detailed pathway reconstruction--the case of VHL (von Hippel-Lindau) protein and angiogenesis regulatory pathway. Protein Sci. 2004 Mar;13(3):786-96. Epub 2004 Feb 06.