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Query: sp|Q96K12|FACR2_HUMAN Fatty acyl-CoA reductase 2 OS=Homo sapiens GN=FAR2 PE=2 SV=1, from H.sapiens

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSTIAAFYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILDSKLFEKVKEVCPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVRFDDTLRHAVQLNVTATRQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYPCPVEPKKIIDSLEWLDDAIIDEITPKLIRDWPNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFPGWVDNINGPNGIIIATGKGFLRAIKATPMAVADVIPVDTVVNLMLAVGWYTAVHRPKSTLVYHITSGNMNPCNWHKMGVQVLATFEKIPFERPFRRPNANFTSNSFTSQYWNAVSHRAPAIIYDCYLRLTGRKPRMTKLMNRLLRTVSMLEYFINRSWEWSTYNTEMLMSELSPEDQRVFNFDVRQLNWLEYIENYVLGVKKYLLKEDMAGIPKAKQRLKRLRNIHYLFNTALFLIAWRLLIARSQMARNVWFFIVSFCYKFLSYFRASSTLKVLast
1 -56.400IDP00492 hypothetical protein YPO1559 YPO1559 [Yersinia pestis CO92]  ali follow..  19  3.KNKTGSETLKKLLLTGATGFLGGAVLEKLLLASSDF-NYLLLVRANTPEQGLMRIRENLEK----YLPNELINKININHVLLGDLAEPDSFINDVR----IDDVTHVINCAAIASFG-NNPLIWKVNVEGTLAFGKRMAQVAGLQRFVHVGTAMACTPEADVDERVLSTEND-------------------------AHLVEYTKSKSAIECLLAEHCPTLPLVFARPSIVVGHTRLGCQPSSSIFW------VFRMALMLRKFMCSLDDHIDVIPVDYCADALLYILEYPNLPDD----IYHISAGEKGSVSFSEIDQAMSVAAKQKPVGVNY---------SQVEYTALVQMRNQLKGIFGPC-------------NERLMLKAMRLYGSFAMLNVRFSNERLLSLGMPRTPRFTDYIARCVESSHGMTIQQQMAVDFK......................................................................... 379
2 -25.200IDP00208 putative dehydrogenase YPO1979 [Yersinia pestis CO92]  ali follow..  20  2...........KVLVTGATSGLGRNAAQWLLEA----HEVYAIGRDQLAGEELRKLG---------------------ATFIPLDLTMTT----MEVCQQWLKTCDVVWHCAAKSAPWGNPQDFHQTNVVVTHKLAQAAGR-EGVKRFIHISSP-------------------------AVYFDFRHHHDLPETYRASRFSSHYASSKYAAEQVLHEHYPDTTYVILRPRGLF--------GPHDRVIVPRLLQQLSRDRNVLRLPGGGQAQLDLTFVLNVVHAMMLAT---DNDGLRSGAIYNITNQ--EPQRLVTMLDSLLNQQLHINYTLQ-----------------VPYSLLSVVAAGMELVASMTQKEPLLTRYSVGAVYFDMTL-------------NSERAINELGYRPRYSMAEGIVLGEWLSAQRSGQHG........................................................................... 338
3 -25.100IDP06439 gene: A45L; A45L [Monkeypox virus Zaire-96-I-16] NP_536582 [Monkeypox virus Zaire-96-I-16]  ali follow..  15  2..........AVYAVTGGAGFLGRYIVKLLISA-DDVQEIRVIDIVEDPQPITSKV--------------------KVINYIQCDIN------DFDKVREALDGVNLIIHTAALVDVFGKYNEIMKVNYYGTQTILAACVD-LGIKYLIYTSSMEAIGPNKH----------------------GNPFIGHEHTLYDISPGHVYAKSKRMAEQLVMKNGAKLYTCCLRPTGIYGEGDKLT---------KVFYEQCKQHGNIMYRTVDDDAVHSRVYVGNVAWMHVLAAKYIQYPGSAIKGNAYFCYDYSPSCSYDMFNLLLMKPLGIEQGSRI-------------------RWMLKMYACKNDMKRILFRKPSILNNYTLKISNTTFEVR........................................................................................................................... 315
4 -19.600IDP02780 NAD-dependent epimerase/dehydratase family protein [Bacillus anthracis str. `Ames Ancestor`] GBAA0507 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  19  2.........SKKCLITGGAGFIGSHLAEELVGRGYNVTIV---------------------DNFYKGKNKYHDELMKEIRVIPISV------LDKNSIYELVNQHDVVFHLAAILGVKTTMEKLIETNFDGTRNILQAALKGKKKVVFASTSEVYGKAKPPFSEEGDRLYGATSKIR------------------------WSYAICKTLEETLCLGYALGLPVTIVRYFNIYGPRAKD-----GPYAGVIPRFIAALQGEDILVYGDGEQTRCFTYVSDAVEATIRAM-----DEKVNGEIINIGSENEKSIK......................................................................................................................................................................................................... 250
5 -18.500IDP00650 NAD-dependent epimerase/dehydratase family protein SACOL0113 [Staphylococcus aureus subsp. aureus COL]  ali follow..  20  2..........ERVLITGGAGFIGSHLVDDLQQD----YDVYVLDNYRTG-------------------KRENIKSLADDHVFELDIREYDA-----EQIMKTYQFDYVIHLAALVSVAESVEKPIEINVVATLRLLEIIKKYNHIKRFIFASSAYGDLPDLPKSDQSLILPLSP-----------------------------YAIDKYYGERTTLNYCSNIPTAVVKFFNVFGPRQDPKSQYSGVIS----MFDSFEHNKPFTFFGDGLQTRDFVYVYDVVQSVRLIM----EHKDAIGHGYNIGTGTFTNLL......................................................................................................................................................................................................... 250
6 -18.200IDP90851 gene: rffG; dTDP-D-glucose-4,6-dehydratase [Yersinia pestis CO92] YPO3862 [Yersinia pestis CO92]  ali follow..  18  2..........RRILVTGGAGFIGSAVVRHIIDGTSD----VVVVDKLTYAGNLESLSVVAGSE--------------RYAFEQVDICDSSE-----DRVFAQYQPNVVMHLAAESHVDRSIDGPIETNVVGTYTLLEAARHAKQAFRFHHIST-----------DEVYGDLHGTDDLFTETTPYAPS--------------SPYSASKASSDHLVRAWLRGLPTLVTNCSNNYGPYHFPIPLVILNA-----------AGKPLPVYGNGAQVRDWLYVEDHARALYQVV-----TEGVVGETYNIGGHNERKN.......................................................................................................................................................................................................... 259
7 -18.100IDP01194 gene: rfbB; dTDP-glucose 4,6-dehydratase BA_1230 [Bacillus anthracis str. Ames]  ali follow..  18  2...........NILVTGGAGFIGSNFVHYMLQSYETYK--IINFDALTYSGNLNNVKSIQDHP--------------NYYFVKGEIQNGEL-----EHVIKERDVQVIVNFAAESHVDRSIENPYDTNVIGTVTLLELVKK-YPHIKLVQVST-----------DEVY-------SLGKTGRFTEETPLAPNSP---------YSSSKASADMIALAYYKQLPVIVTRCSNNYGPYQYPIPLMVTNA-----------EGKKLPLYGDGLNVRDWLHVTDHCSAIDVVL-----HKGRVGEVYNIGGNNEKTNV......................................................................................................................................................................................................... 250
8 -18.000IDP90552 gene: rfaD; ADP-L-glycero-D-mannoheptose-6-epimerase YPO0058 [Yersinia pestis CO92]  ali follow..  15  2............IIVTGGAGFIGSNIVKALNNI--GYKDILVV----DNLKDGTKFVNLVDLDIADYMDKED--------------------VASIVAGDDMGDIDAIFHEGACSSTTEWDGKYMDNNYQYSKDILHFCLDRSIPFLYASSAATYGGRTDNFIEDRQYEQPL-----------------------------NVYGYSKFLFDQYVREILPDSQICGFR-----------------NVYGPREGHKGSMASVAKLFAGSENFKRDFIYVGDVADVNLWFW------QNGVSGIFNCGTGRAESFQ......................................................................................................................................................................................................... 244
9 -18.000IDP02551 gene: waaD; ADP-L-glycero-D-mannoheptose-6-epimerase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1151c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  16  2...........KIAITGGAGFIGSQLALNLQEK----HEILII-------------DKMRSSATFENGNLQSFGHFKNLLEFDGELFAGDINDEKVLKKIEDFKPEIIFHQAAISDTTFDQTKVLQTNLNTFKDFIELSIDLNAKLIYASSASVYGDAKSPQTVGKDEEP-------------------------------NPYAFSKLMMDKLAKKYYDKAHLVGLR-----------------NVYGKGEFYKNKTASMVRLFEGSDQIYRDFTYIKDVISANLIAL-------DSKCGVYNVGSGKARTFQ......................................................................................................................................................................................................... 249
10 -17.600IDP00701 gene: cap5N; capsular polysaccharide biosynthesis protein Cap5N SACOL0149 [Staphylococcus aureus subsp. aureus COL]  ali follow..  19  3..........KNILITGVHGYIGNALKDKLIEQGHQVDQINVR--------------------------------------------------NQLWKSTSFKDYDVLIHTAALVHNNSPQARLMQVNMLLTKQLAQKAKA-EDVKQFIFMSTMAVYGKEGHVGKS-----------------------DQVDTQTPMNPTTNYGISKKFAEQALQELISSFKVAIVRPPMIYG------AHCPGNFQRLMQLSKRL------PIIPNINNQRSALYIKHLTAFIDQLI------SLEVTGVYHPQDSFYFDTS......................................................................................................................................................................................................... 218
11 -17.500IDP01944 putative sugar-nucleotide epimerase/dehydratease [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1427c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  17  2.........SKKVLITGGAGYIGSVLTPILLEKGYEV--------------------CVIDNLMFDQISLLSCFHNKNFTFINGDAM------DENLIRQEVAKADIIIPLAALVGAPLCKRNAKMINYEAVKMISDFASPSQ---IFIYPNTNYGIGEKDAMCT-------------------EESPLRPISE---------YGIDKVHAEQYLLD---KGNCVTFRLATVFGISPRM------RLDLLVNDFTYRAYRDKFIVLFEEHFRRNYIHVRDVVKGFIHG---IENYDKMKGQAYNMGLSSAN............................................................................................................................................................................................................ 239
12 -17.200IDP90559 gene: rfaD; ADP-L-glycero-D-mannoheptose-6-epimerase [Vibrio cholerae O1 biovar eltor str. N16961] VC0240 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  14  2............IIVTGGAGMIGSNIIKALNER--GITDILVVDHLKNGRK-----------------FKNLVDLQIADYMDRDDF------LAQIMAGDDFGFIDAIFHEGACSATTEWDGKYVLNNYEYSKELLHYCLDREIPFLYASSAATYGETDTFIEEPQYEGA-------------------------------NVYGYSKQQFDNYVRRLWLDSQITGFR-----------------NVYGPREQHKGSMASVAKLFAGSENFKRDFVYVGDVAAVNLWFL------DHGVSGIFNCGTGKAESFN......................................................................................................................................................................................................... 249
13 -17.000IDP95160 uridine diphosphate galacturonate 4-epimerase [Klebsiella pneumoniae subsp. pneumoniae MGH 78578] YP_001336140 [Klebsiella pneumoniae subsp. pneumoniae MGH 78578]  ali follow..  15  2...........KFLVTGAAGFIGFHIAQRLLNEGHNVVGIDNMNDYYDVSLKQARLDRLAY---------------PAFHFQQLDLADREG-----AKLFATEQFDRVIHLAAQAGVRYSLENPADANLMGYLNILEGCRH-TKVKHLVYASSS-----------SVY----------------LNRKMPFSTEDSVDHPVSLYAATKKANELMAHTYSHGIPTTGLRFFTVYGPWGRP--------MALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIVEAVVRVL-GSPATSSAPYRVYNIGNSSPVELM......................................................................................................................................................................................................... 269
14 -14.600IDP06311 UDP-glucose 4-epimerase [Streptococcus pneumoniae TIGR4] NP_346261 [Streptococcus pneumoniae TIGR4]  ali follow..  16  2...........AILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSI-----------------LVLDRIEAITGIRPVFYELDVCDKQA-----RKVFEQESIDAAIHFAGYKAVGESVQKPVKNNIMSTLALVEVMSE-FNVKKIVFSSSAYGINNQSPLIETMQTSAT-----------------------------NPYGYTKVMLEQILKDVHSEWSIALLRYFNPIGAHESGLIG--EDPSGIPNYIAQVAVGKLSELSVDGTGVRDYIHVVDLAIGHIKAL--EKVSEKTDVYIYNLGSGEGTSV.......................................................................................................................................................................................................... 268
15 -14.600IDP02579 gene: galE; UDP-glucose 4-epimerase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1131c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  17  2...........KILISGGAGYIGSHTLRQFLKTDHEI-------------------------CVLDNLSKGSKIAIEDLQKTRAKFFEQDLSDFQGVKALFERKFDAIVHFAASIEVFESMQNPLMNNTVNTTNLIETCLQ-TGVNKFIFSSTAYGEPQTPVVSETSPLAPI-----------------------------NPYGRSKLMSEEVLRDASMEFKHCILRYFNVAGACMDYTLGQRYPKATLIKVAAECAAGKRDKLFIDGTCIRDFIHVDDISSAHLAA---LDYLKENESNVFNVGYGHGFSV.......................................................................................................................................................................................................... 264
16 -14.600IDP02553 polysaccharide biosynthesis protein [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1293 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  17  1......MFNKKNILITGGTGSFGKTYTKVLLENYKPNKIIIYSRDELKQFEMASVFNAP------------------CMRYFIGDVR------DKERLSAAMRDVDFVIHAAAMKHVEYNPMECIKTNIHGAQNVIDACFE-NGVKKCIALST----------DKACNPV-------------------------------NLYGATKLASDKLFVAANKQTRFGVTRYGNVVGSRGSVVPFFKKLIS----------EGAKELPITDTRMTRFWISLEDGVKFVLSNF.................................................................................................................................................................................................................................. 215
17 -14.500IDP00758 gene: cap5E; capsular polysaccharide biosynthesis protein Cap5E SACOL0140 [Staphylococcus aureus subsp. aureus COL]  ali follow..  23  1......MFDDKILLITGGTGSFGNAVMKQFLDSNI--KEIRIFSRDEKKQDIRKKYNNS------------------KLKFYIGDVR------DSQSVETAMRDVDYVFHAAALKQVEFFPVEAVKTNIIGTENVLQSAIH-QNVKKVICLST----------DKAAYPI-------------------------------NAMGISKAMMEKVFVAKSEQTLICGTRYGNVMASRGSVIPLFIDKIKAGEPLTI-----------TDPDMTRFLMSLEDAVELVVHAF.................................................................................................................................................................................................................................. 213
18 -14.300IDP06240 UDP-glucose 4-epimerase [Streptococcus pneumoniae TIGR4] NP_346051 [Streptococcus pneumoniae TIGR4]  ali follow..  17  3..........EKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNR-----------------KSLEVVEGITGVEIPFYEADIRDTDT-----RDIFKQEEPTGVIHFAGLKAVGESTRIPLDNNIAGTVSLLKAMEE-NNCKNIIFSSSAYGDPHTVPILEDFPLSVT-----------------------------NPYGRTKLMLEEILTDIYKEWNVVLLRYFNPIGAHESGDLG--GIPNNLLPYVTQVAVGKLEQVQVDGTGVRDYIHVVDLAKGHVAAL--KKIQKGSGLNVYNLGTGKGYSV.......................................................................................................................................................................................................... 270
19 -14.000IDP02480 gene: galE-2; UDP-glucose 4-epimerase [Bacillus anthracis str. `Ames Ancestor`] GBAA5700 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  16  2...........AILITGGAGYIGSHTCVELLNNNYKIIVVDNLSNSSI-----------------ESLNRVKEITGKQFEFYKENVLNREK-----NEIFLENNIEAVIHFAGFKAVGESTTTPLYNNIISAIVLCDVMQK-HNVKNFIFSSSAYGIPKTLPITEEFPLSVT-----------------------------NPYGQTKLMIEQIMRDVADEWSIALLRYFNPFGAHQSGRIG--GIPNNLMPYVTQVAVGKLKELNIDGTGVRDYIHVVDLAKGHVKAL--EKVLKTKGIEAYNLGTGKGYSV.......................................................................................................................................................................................................... 268
20 -12.900IDP91002 bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase [Yersinia pestis KIM 10] y1919 [Yersinia pestis KIM10+]  ali follow..  16  314........RRTRVLILGVNGFIGNHLTERLLQD--DRYEVYGL-------IGSDAISRFLGNPAFH---------------VEGDISIH-----SEWIEYHIKKCDVILPLVAIAEYTRNPLRVFELDFEENLKIVRDCVKYNKRIVFPSTSEVYGMCDDKEFDEDTSRLIVGP----------------------INKQRWIYSVSKQLLDRVIWAYGEGLKFTLFRPFNWMGPRLDNLDA-IGSSRAITQLILNLVEGSPIKLVDGGAQKRCFTDIHDGIEALFRII--ENRDGCCDGRIINI-GNPTNEASIRELAEMLLTSFENHE......................................................................................................................................................................................... 589
21 -12.600IDP02149 gene: fcl; putative fucose synthetase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1428c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  10  3........TNSKIYIAGHKGTAGTALVENLQKR--GFNNLVLKTRQELDLVNQQAVAKFFKE----------------------------------------EKPEYVFLTAVLPCGAANVAQRADFNLMIQNNVIHNSFL-NNVKKLVFFGSGYPENAKNPLKE------------------------EYLFQGDLEYGAYSFGAAKIAGAIMCESYNIGTNFITLVPALLRKFHLAKLLSKMNNFEEAKEYLHNFGIS---EIWGTGKVRREFIHSDDLADVAIYTM-DLIKDRKSKNTHINIGTGIDYSIK......................................................................................................................................................................................................... 284
22 -10.500IDP93871 dTDP-4-dehydrorhamnose reductase [Yersinia enterocolitica subsp. palearctica Y11] YP_006005171 [Yersinia enterocolitica subsp. palearctica Y11]  ali follow..  20  3..........RKILITGGTGMLGAYVTSALKDT-----NVIVTERNTLNLSVPEAIFSYITA----------------------------------------EKPDVILHFAAETDVDREPARAGIYNHLATEQIAQAAKFCG--AWLLYLSSVFGGEGKLSYNELDIPLPM-----------------------------NYYGRSKLIGESSVRNACTN-NHLIIRAGWMIGGGPDKDHKFVGK------IIQQIKAGSTSIKAVSDRLGSITSAMQLCNFIIWAI-------NKRHTGTLHFASSGT--ISRFDIACAIGDLL............................................................................................................................................................................................. 233
23 -10.100IDP90837 gene: rfbD; dTDP-4-dehydrorhamnose reductase [Shigella flexneri 2a str. 2457T] S2226 [Shigella flexneri 2a str. 2457T]  ali follow..  22  2...........NILLFGKTGQVGWELQRAL----APLGNLIALDVH----STDYCGDFSNPEGVAETVKKIRPD--------------------------------VIVNAAAHTAVDSEPNFAQLLNATCVEAIAKAANEVG--AWVIHYSTDYV---------------------------FPGNGDTPWLETDATAPLNVYGETKLAGEKALQEHCAK---LIFRTS------------WVYAGKGNNFAKTMLRLAVINDQFGAPTGAELLADC-------TAHAIRVAANKPEVAGLYHLVAGGT--TTWHDYAALVFEEARR........................................................................................................................................................................................... 236
24 -10.100IDP01195 gene: rfbD; dTDP-4-dehydrorhamnose reductase BA_1231 [Bacillus anthracis str. Ames]  ali follow..  22  3..........ERVIITGANGQLGKQLQEELNPE-----DIYPFDKKLLDITNISQVQQVVQE----------------------------------------IRPHIIIHCAAYTKVDKERDLAYVINAIGARNVAVASQLVG--AKLVYISTDYV---------------------------FQGDRPEGYDEFHNPAPINIYGASKYAGEQFVKELHNK---FIVRTS------------WLYGKYGNNFV-----KTMIRLGKEREEISVVADQIGSPTYVADLNVMINKLIHTSLYGTYHVSNTGS--CSWFEFAKKIFSYA............................................................................................................................................................................................. 228
25 -9.770IDP02802 short chain dehydrogenase/reductase family oxidoreductase [Bacillus anthracis str. `Ames Ancestor`] GBAA3471 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  16  2...........RVLITGGNRGLGLQLVKVFHEN----HIIYPLVRTEVAVTQLKQMFS------------------CRCFPILADLAADSTEQIKKQLEEYTEYMDLVINNAGITG--EELTDLFNIHCLGVIRAVKGTYMASDHPRIINVSSRLGSLHKMANKEFPQGHFS------------------------------SYRIAKAAQNMLTLCLQQEFENKGISVTAI--------PGKLKTEIGAFDANMTPAEGTKNIY.......................................................................................................................................................................................................................................................... 210
26 -9.420IDP05213 capsular polysaccharide biosynthesis protein [Clostridium difficile 630] CD2769 [Peptoclostridium difficile 630]  ali follow..  15  245LREISNYIEGKVILITGGGGSIGSELCRQIAGFNP--KELIIVDNYENNASIQQELLRKYKNKL-------------DLKTVIASIREE----KRMDEIFNKYKPEVVFHAAAHKHMESSPGEAIKNNIFGTLNIAGLSSKY-RAKKFVLIST---------------DKAVNPTNIMGATKRAAEMIIQTMNAEVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGAMA-ILDLAKNLIKFSGFEPDVDIKIEPGEKLYEELLMSEEGLLDTEHKKIFIGRPIDVDREKIT......................................................................................................................................................................................................... 551
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 7 0 3   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zhang B, Jaroszewski L, Rychlewski L, Godzik A. Similarities and differences between nonhomologous proteins with similar folds: evaluation of threading strategies. Fold Des. 1997;2(5):307-17.