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Query: sp|O15229|KMO_HUMAN Kynurenine 3-monooxygenase OS=Homo sapiens GN=KMO PE=1 SV=2, from H.sapiens

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDSSVIQRKKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDTRVATFTRGRSINLALSHRGRQALKAVGLEDQIVSQGIPMRARMIHSLSGKKSAIPYGTKSQYILSVSRENLNKDLLTAAEKYPNVKMHFNHRLLKCNPEEGMITVLGSDKVPKDVTCDLIVGCDGAYSTVRSHLMKKPRFDYSQQYIPHGYMELTIPPKNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCTLFMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKSHCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAISDLSMYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHWQKKVINKGLFFLGSLIAISSTYLLIHYMSPRSFLRLRRPWNWIAHFRNTTCFPAKAVDSLEQISNLISRLast
1 -129.000sp|O15229|KMO_HUMAN Kynurenine 3-monooxygenase OS=Homo sapiens GN=KMO PE=1 SV=2  ali  100  1MDSSVIQRKKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDTRVATFTRGRSINLALSHRGRQALKAVGLEDQIVSQGIPMRARMIHSLSGKKSAIPYGTKSQYILSVSRENLNKDLLTAAEKYPNVKMHFNHRLLKCNPEEGMITVLGSDKVPKDVTCDLIVGCDGAYSTVRSHLMKKPRFDYSQQYIPHGYMELTIPPKNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCTLFMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKSHCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAISDLSMYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHWQKKVINKGLFFLGSLIAISSTYLLIHYMSPRSFLRLRRPWNWIAHFRNTTCFPAKAVDSLEQISNLISR 486
2 -49.100sp|Q14534|ERG1_HUMAN(removed signalp:1-43) Squalene monooxygenase OS=Homo sapiens GN=SQLE PE=2 SV=3  ali follow..  16  74.STSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEP------DRIVGEFLQPGGYHVLKDLGLGDTVEGLDAVVNGYMIHDQESKSEVQIPNNQVQSGRAFHHGRFIMSLRKAAMAEPNAKFIEGVVLQLLEEDDVVMGVQYKDGDIKELHAPLTVVADGLFSKFRKSLVSNKVSVSSHFVGF-------LMKNAPQFKANHAELILANPSPVLIYQISSSETRVLVDI-------RGEMPRNLREYMVEKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGGGMTVAFKDIKLWRKLLKGIDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSATDDSLHQLRKACFLYFKLG-PLVLIGHFFAVAIYAVYFCFKSEPWITKPRALLSSGAVLYKACSV................................................... 517
3 -38.200sp|Q9Y2Z9|COQ6_HUMAN Ubiquinone biosynthesis monooxygenase COQ6 OS=Homo sapiens GN=COQ6 PE=1 SV=2  ali follow..  16  29.GASTDTVYDVVVSGGGLVGAAMACALGYHDKKILLLEAGPKKVLEKLSETYSNRVSISPGSATLLSSFGAWDHICNMRYAFRRMQVWDACSEALIMFDKDNLDDMYIVENDVIMHALTKQLEAVSRVTVLYRSKAIRYTDSSPWVHITLGDGS--TFQTKLLIGADGHNSGVRQAVIQNVSWNYDQSAV------VATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWSDADHTDFIDTAGAMLQYAVSLLLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFN-VSHLTGYETERQRHNTALLAAT.............................................................................................................................. 427
4 -29.000sp|Q8TDZ2|MICA1_HUMAN NEDD9-interacting protein with calponin homology and LIM domains OS=Homo sapiens GN=MICAL1 PE=1 SV=2  ali   16  78.QGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFSRHNV-------LHLWPFTIHDLRALGAKKFYGRFCTG-----------------------TLDHISIRQLQLLLLKVALLL-GVEIHWGVTFTGLQPPPRKGSGWRPPAQLANYEFDVLISAAGGKFVPEGFK..................................................................................................................................................................................................................................................................................................................... 228
5 -28.700sp|O94851|MICA2_HUMAN Protein MICAL-2 OS=Homo sapiens GN=MICAL2 PE=1 SV=1  ali   20  79KRGKSCTNTKCLIVGGGPCGLRTAIELAYLGAKVVVVEKRDSFSRN---------NVLHLWPFTIHDLRGLGAKKFYGKFCAGS---------------------IDHISIRQLQLILFKVALML-GVEIHVNVEFVKVLEPPEDQEFLPTDHSLSEFEFDVIIGADGRRNTLEGFR..................................................................................................................................................................................................................................................................................................................... 233
6 -28.300sp|Q7RTP6|MICA3_HUMAN Protein MICAL-3 OS=Homo sapiens GN=MICAL3 PE=1 SV=2  ali   17  79KKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSRN---------NVLHLWPFTIHDLRGLGAKKFYGKFCA---------------------GAIDHISIRQLQLILLKVALIL-GIEIHVNVEFQGLIQPPEDQEVHPKTHPVSEYEFEVIIGGDGRRNTLEGFR..................................................................................................................................................................................................................................................................................................................... 233
7 -22.200sp|Q16134|ETFD_HUMAN Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens GN=ETFDH PE=1 SV=2  ali   10  63..ERFAEEADVVIVGAGPAGLSAAVRLKQKDIRVCLVEKAAQIG-----AHTLSGACLDPGAFKELFPDWKEKGAPLNTPVTEDRFGILTEKYRIPPGLPMNNHGNYIVRLGHLVSWMGEQAEAL-GVEVYPGYAAAEVLFHDDGSVKKATFERGLELHAKVTIFAEGCHGHLAKQL..................................................................................................................................................................................................................................................................................................................... 256
8 -22.000sp|Q16134|ETFD_HUMAN Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens GN=ETFDH PE=1 SV=2  ali   9  22..........................................................................................................YIVRLGHLVSWMGEQAEAL-GVEVYPGYAAAEVLFHDDGSVKKATFERGLELHAKVTIFAEGCHGHLAKQLYKKFDLRANCEPQTYGIGLKELWVIDEKNWKPGRVDHTHTYGGSFLYHLNEGEPLVALGLVVGLDYQNPYLSPFREFQRWKHH-----PSIRPTLEGGKRIAYGARAL-GFQSIPKLTFPGGLLIGCSPGFMNVPKIKGTHTAMKSGILAAESIFNQENLQSKTIGLHVTEYEDNLKN................................................................................................................................... 291
9 -16.100sp|Q9Y2Z2|MTO1_HUMAN Protein MTO1 homolog, mitochondrial OS=Homo sapiens GN=MTO1 PE=1 SV=2  ali   14  30.AAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKG----HLMREVDALDGLCSRICDQSGVHYKVLNRRKGPAVWGLRAQ----IDRKLYKQNMQKEILNTPLLTV-QEGAVEDLILTEPEPEHTGKCVDGSTVYAESVILTTGTFLRGMIVI..................................................................................................................................................................................................................................................................................................................... 203
10 -15.800sp|Q9P0Z9|SOX_HUMAN Peroxisomal sarcosine oxidase OS=Homo sapiens GN=PIPOX PE=2 SV=2  ali follow..  12  2..AAQKDLWDAIVIGAGIQGCFTAYHLAKHRKRILLLEQFFLPHSRGSSHGQSRIIRKAKTIQANLSRQRVEHQCLSSEELKQRFPNIRLPRGEVGLLDNSGG----VIYAYKALRALQDAIRQL-GGIVRDGEKVVEIN-PGLLVTVKTTSR---SYQAKSLVITAGPWT---NQLLRPLGIEMPLQTLRINVCYWREMVPGSYGVSQAFPCFL-GLCPHHIYGLPTGEYPGLMKVSYHHGNHADPEERQILSSFVRDHLPDLKPEPAVIESCMYTNTPDEQFILDRHPK---YDNIVIGAGFSGHGLAPVVGK----------ILYELSMKLTPSYD--LAPFRISRFPSLGK................................................................................................................................... 387
11 -14.900sp|Q8IWF2|FXRD2_HUMAN(removed signalp:1-26) FAD-dependent oxidoreductase domain-containing protein 2 OS=Homo sapiens GN=FOXRED2 PE=1 SV=1  ali   14  1....VPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFERAPRP---------GSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLLFRHYSRAYF---DARDMVRYLGDFADTL-GLRVQYNTTIAHVTLDKDR-YFILTDQKGQVHQCSVLFVATGLSV--------PNQVDFPGSEYAEGYESVSVDPED----VGQNVLILGRGNSAFETAENILGVTNFIHMLSRSR.................................................................................................................................................................................................................................................... 220
12 -14.400sp|Q96RQ9|OXLA_HUMAN(removed signalp:1-21) L-amino-acid oxidase OS=Homo sapiens GN=IL4I1 PE=1 SV=1  ali follow..  9  33..NRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIQNTGWIGELG-AMRMPSS-HKLCQGLGLNEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGEGNLWDLLPRALLSSLSGLVLLNAPVVAMTQGPHDVHVQIETRNLKVLKADVVLLT--ASGPAVKRILPRHMQEALRRLHYVPATKVFLSFRRPFWREEHIE---RPSRMIFYPPPREGALLLASYTWSDAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTFVVQPPALWQTEKDDWTVPYGRIYFAGEHTAYPHGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQGHVHGVAS................................................................................................................................ 514
13 -14.300sp|P27338|AOFB_HUMAN Amine oxidase [flavin-containing] B OS=Homo sapiens GN=MAOB PE=1 SV=3  ali follow..  11  1....MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVRTYTLRNQKVKYVDLGGSYVEEWDNMTMKELLDKLCWTESAKQLATQCGGTTRIISTTNGGQERKFVGG--SGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIRNQMITRVPLGSVIKCI-KDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKA------RKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAEAGERAAREILHAMGKIPED..................................................................................................................................................... 460
14 -14.100sp|Q9UI17|M2GD_HUMAN(removed signalp:1-23) Dimethylglycine dehydrogenase, mitochondrial OS=Homo sapiens GN=DMGDH PE=1 SV=2  ali   13  20.ETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTWHAAGNLKKIHYDSIKLYEKLGQVVGFHQPGIRLATTPVRVDEFKYQMTRTGWHATEQYLIEPEKIQEMFLAAGARKCGALLKYPAPVTSLKARSDGTWVETPQG---SMRANRIVNAAGFWAREVGKMIG................................................................................................................................................................................................................................................................................................................... 237
15 -14.000sp|P21397|AOFA_HUMAN Amine oxidase [flavin-containing] A OS=Homo sapiens GN=MAOA PE=1 SV=1  ali follow..  11  7.ASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVRTYTIRNEHVDYVDVGGAHADKWDKMTMKELIDKICWTKTARRFAYQCGGTTRIFSVTNGGQERKFVGG--SGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIRNQLIQRLPMGAVIKCM-KDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKA------DRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAEAGERAAREVLNGLGKVTEK..................................................................................................................................................... 469
16 -13.600sp|Q8NCN5|PDPR_HUMAN Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial OS=Homo sapiens GN=PDPR PE=1 SV=2  ali   15  36.SMALPTQAQVVICGGGITGTSVAYHLSKMGWKDIVLLEQGRLAAGSTRFCAGIEQKMADYSNKLYYQLGIQTGYTRTGIFLAQTQDRLISLKRINAGLNVIGIPSEIISPKKVAELHLASAASQNGVQIYDRTSVLHVMVKKGQVTVETDKG---QIECQYFVNCAGQWAY.......................................................................................................................................................................................................................................................................................................................... 246
17 -13.500sp|Q6NUM9|RETST_HUMAN(removed signalp:1-18) All-trans-retinol 13,14-reductase OS=Homo sapiens GN=RETSAT PE=2 SV=2  ali follow..  10  43.ANQVPEKLDVVVIGSGFGGLAAAAILAKAGKRVLVLEQHTKA-CCHTFGKNGLEFDTGIHYIGRMEEGSIGRFILDQITE-KEYPMYSGEKAYIQGLKEKFPQEEAIIDKSEIAFHTIPVIQRA-GGAVLTKATVQSVDSAGKACGVSVKKGHEVNIYCPIVVSNAGLFNTYEHLLPGNARCLPGVKQQLGTVVFICLRGTKEDLHLPSTNYYVYYDTDMTWEDRFPGRSTMIMLIPTAYEWFEEWQAVEASMSVVLKLFPQLEGKVESVTAGSPLTAAPRGACYGADHDLGRLHPNLYLTGQDIFT-------GLVGALQGALLCSSAIRNLYSDLKNLDSRIRAQKKKN...................................................................................................................................... 592
18 -13.400sp|Q9UL12|SARDH_HUMAN Sarcosine dehydrogenase, mitochondrial OS=Homo sapiens GN=SARDH PE=1 SV=1  ali   15  60.SRPLPSTANVVVIGGGSLGCQTLYHLAKLGMGAVLLER-ERLTSGTTWHTAGVEVELLAHTRRVVEETGLHTGWIQNGLFIASNRQRLDEYKRLMSLGKAYGVESHVLSPAETKTLYLARAASARGAQVIENCPVTGIRVWTDDFRVAGVETQHGSIQTPCVVNCAGVWASAVGRMAG................................................................................................................................................................................................................................................................................................................... 283
19 -13.100sp|Q8N2H3|PYRD2_HUMAN Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 OS=Homo sapiens GN=PYROXD2 PE=2 SV=2  ali follow..  11  28.RGGLKPEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEIIPGLELKKHGLRLHRCLLLGTDMAENQKQIAQ--FSQKDAQVFPKYEEFMHRLALAIDPGALSDAIASSATTH-GASIFTEKTVAKVQVNSEGCVQGVVLEDGTEVRSKMVLSNTSPQITFLKLTPQEWLPEEFLERISQLLLHQAFEDAMDGLPSHRPVIELCIPSSLDPTLAPPGCHVVSLFTQYMPYTLAGGKAADRVFDCIEVYAPGFKDSVVGRDILTPPDAMSLDQLYFARPVPLHSGYRLYLCGSGAH---PGGGVMGAAGRNAAHVAFRDLKS......................................................................................................................................................... 580
20 -13.000sp|Q8NB78|KDM1B_HUMAN Lysine-specific histone demethylase 1B OS=Homo sapiens GN=KDM1B PE=1 SV=3  ali   17  75LLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIRVWDDKSFKGVTVGRGAQIVNGCINNPVALMCEQLGISMERCDLIQEGGRIT....................................................................................................................................................................................................................................................................................................................................................................................................... 175
21 -12.900sp|Q96CU9|FXRD1_HUMAN FAD-dependent oxidoreductase domain-containing protein 1 OS=Homo sapiens GN=FOXRED1 PE=1 SV=2  ali follow..  13  57.SHLPPEHSDVVIVGGGVLGLSVAYWLKKLEIRVLVVERDHTYSQASTGLSVGENIQLSLFSASFLRNIAVVDAFNPSGYLLLASEKDAAAMESNVKVQRQEGAKVSLMSPDQLRNKFLRRKVQSLGVLFCQGEVTRFVSSSQRMLTTDDKA-EYQPVECAIVINAAGAWSAQIAALAGVGEGPPGTLQG----TKLPVEPRKRYVYVWHCPQGPGLETPLVAYFRREGLGSNYLGGRSPTEQEEPDPANDFFQDKVWPHLALRVPAFETLKVQSAWAGYYDYNTFDQNG----------VVGPHPYFATGFSGHGLQQAPGIGRAVAEMVLKGRFQTID-LSPFLFTRFYLGEKIQENN.............................................................................................................................. 484
22 -12.800sp|P26374|RAE2_HUMAN Rab proteins geranylgeranyltransferase component A 2 OS=Homo sapiens GN=CHML PE=1 SV=2  ali   21  1MADNLPTEFDVVIIGTGLPESILAAACSRSGQRVLHIDSRS............................................................................................................................................................................................................................................................................................................................................................................................................................................................. 41
23 -12.600sp|Q8NBM8|PCYXL_HUMAN(removed signalp:1-22) Prenylcysteine oxidase-like OS=Homo sapiens GN=PCYOX1L PE=1 SV=2  ali follow..  10  2.....APPGKIAVVGAGIGGSAVAHFLQQHRVQIDVYEKGTTISVNKQHYESGAASFHSLS-QDFVKLLGLRSGVEELLYSLGESTFVNMTQHSVAESLLQVGVTQRFIDD---NKLVCSGLLKLTKANVIHATVTSVTLHSTEGKALYQNEVGNSSDFYDIVVIATPLHLDNSSSNLTFAGFHPPIDDVQGSFQPTVVSLVHGYLNSSYFGFPDPKLFPFANILTTDFPSFFSASFRRKQPQEAAVWRVQSPKPLFRTQLKTLFRSYYSVQTAEWQAHPLYGSRPTLPRFA---HDQLFYLN-ALEWAASSVEVMAVAAKNVALLAYNRWYQDLDKIDQK-DLMHKVKTE....................................................................................................................................... 471
24 -12.400sp|Q9H9P8|L2HDH_HUMAN L-2-hydroxyglutarate dehydrogenase, mitochondrial OS=Homo sapiens GN=L2HGDH PE=1 SV=3  ali follow..  15  42.RSASTSSFDIVIVGGGIVGLASARALILRSLSIGVLEKEKDLAVHQTGHNSGVGIYYKPESLKAYKQCG-LQALYEKGLQNGVPGLRLIQQEDIKKKEPYDCPHTGIVDYRQVALSFAQDFQEA-GGSVLTNFEVKGIEMAKESPSRSIDGTKGEEIRCQYVVTCAGLYS........................................................................................................................................................................................................................................................................................................................... 263
25 -12.400sp|O60341|KDM1A_HUMAN Lysine-specific histone demethylase 1A OS=Homo sapiens GN=KDM1A PE=1 SV=2  ali   15  122.PLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRV-RVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELQKCPLYEANGQAVPKEKDEM---------EQEFNRLLEATSYLSH....................................................................................................................................................................................................................................................................................................................................................................... 244
26 -12.400sp|Q9UJX0|OSGI1_HUMAN Oxidative stress-induced growth inhibitor 1 OS=Homo sapiens GN=OSGIN1 PE=2 SV=2  ali follow..  8  92LGASSSEPLPVIIVGNGPSGICLSYLLSGYTPYTKPDAIHPHPLLQRKLTEADTDFGGNMKSVLTWKHRGAWHSIEGSMVILSQGQWMGLPDLEVKDWMQKKGLRNSRATAGDIAHYYRDYVVKKGGHNFVSGAVVTAVEWGTSGFLTRNQAQQPFSLWARNVVLATGTFDSPARLGIPGEALPFIHHELSA-----AATRVGAVTPASDPVLIIGAGLSAADAVLYARHYNIPVIHAFRRAVDDPGLVFNQLPKMLYPEYHKVHQMMREQSILSPSPYEGYRSLPRHQLLCFKEDCQAVFQGVGVSLVLVLIGSHPDLSFLPGAGADQPLSAKRNPIDVDPFTYQSTRQEGLYAMGPLAGDNFVRF---VQGGALAVASSLLRKETRKPP............................................................................................... 560
27 -12.300sp|O95831|AIFM1_HUMAN Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens GN=AIFM1 PE=1 SV=1  ali   11  125.QDKAPSHVPFLLIGGGTAAFAAARSIRARDPGARV-------------------LIVSEDPELPYMRPPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSFYVSAQD--------PHIENGGVAVLTGKKVVQLDVRDNMVKL--NDGS--QITYEKCLIATGGTPR.......................................................................................................................................................................................................................................................................................................................... 265
28 -12.100sp|Q9UHG3|PCYOX_HUMAN(removed signalp:1-27) Prenylcysteine oxidase 1 OS=Homo sapiens GN=PCYOX1 PE=1 SV=3  ali follow..  10  1.AELRAPPDKIAIIGAGIGGTSAAYYLRQKDVKIDLFEREETMMVQGQEYEAGGSVIHPLN-KRFVKDLGLSSSVEKLLHALGGDDFLGMLNRTLLETLQKAGFSEKFLNE---NKLVCSGLLQASKSNLISGSVMYIEEKTKTKYTGNPTGTETRSDFYDIVLVATPLNRKMSNITFLNFDPPIEEFHQYYQHIVTTLVKGELNTSIFSSRPIDKFGLNTVLTTDNSDLFINSIGIVPSVREKEDPEPSTDGTYVWKIFSQE-KAQILKLFLSYDYAVKKPWLAYPHKCPSIILHDRLYYLN-GIECAASAMEMSAIAAHNAALLAYHRWNGHTDMIDQD-GLYEKLKTE....................................................................................................................................... 477
29 -12.000sp|Q6QHF9|PAOX_HUMAN Peroxisomal N(1)-acetyl-spermine/spermidine oxidase OS=Homo sapiens GN=PAOX PE=1 SV=3  ali   10  1......PVPSVGEYLKKEIGQHVARLCGHSAFHLRVLEATARARCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGDQTREFLHAAETPVPSVGEKGYQGLTNCMMAALPEDTVVFEKPVKTIHGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAI........................................................................................................................................................................................................................................................................................................ 300
30 -11.700sp|Q9Y6N5|SQRD_HUMAN Sulfide:quinone oxidoreductase, mitochondrial OS=Homo sapiens GN=SQRDL PE=1 SV=1  ali follow..  9  37.SHAARNHYEVLVLGGGSGGITMAARMKRKAENVAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPTASV-------------------------------------------------------PSGVEW-IKARVTELNPDKNCIHTD----DDEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRALQHRRYPNVFGIGDCTNLPTSKTAA---AVAAQSGILDRTISV......................................................................................................................................................... 362
31 -11.600sp|P31513|FMO3_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 3 OS=Homo sapiens GN=FMO3 PE=1 SV=5  ali follow..  11  2.......GKKVAIIGAGVSGLASIRSCLEEGLEPTCFEKSNDI--------------------------GLDHAEEGRASIYKSVFSNSSKEMMCFPDFPFPDDFPNFMHNSKIQEYIIAFAKEKN--YIQFKTFVSSVNKHPDFDVTTERDGKKESAVFDAVMVCSGHHVYPN------PKESFPGLNHFKGKCFHSRDYKEPGVFNGKRVLVVGLGNSGCDIATELSRTAEQVMISSRSGTFLKNNLPTAISDWLYVKQMNARFKHENYGLMPLNGVLRKEPVFNDELPASILCGIVSVKPNVKEETSAIFEDGTIFEGIDCVIFATGYSFAYPFLDESIIKSRNNEII....................................................................................................................................... 351
32 -11.500sp|P49326|FMO5_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 5 OS=Homo sapiens GN=FMO5 PE=2 SV=2  ali follow..  12  1.....MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDI--------------------------GLENPEEGRASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHNAQVLEYFRMYAKEFD--YIRFKTTVCSVKKQPDFEVVTESEGKKEMNVFDGVMVCTGHHTNAH------PLESFPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGHFIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGNVKEETAAIFEDGSREDDIDAVIFAT............................................................................................................................................................. 330
33 -11.400sp|Q99518|FMO2_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 2 OS=Homo sapiens GN=FMO2 PE=1 SV=3  ali follow..  12  2.......AKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDI--------------------------GVENVEDGRASIYQSVVTNTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFD--YIQFQTTVLSVRKCPDFKVVTQSNGKEQSAVFDAVMVCSGHHILPH------PLKSFPGMERFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGSMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLCGAIKVKSTVKELTETIFEDGTVEENIDVIIFAT............................................................................................................................................................. 329
34 -11.300sp|P31040|DHSA_HUMAN(removed signalp:1-19) Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens GN=SDHA PE=1 SV=2  ali   17  36.YPVVDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALAPAAVVELENYGM-----PFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVAHSLLHTLYGRSLRY-DTSYFVEYFALDLLMENGEIALCIEDGSIHRIRAKNTVVATGGYGRT......................................................................................................................................................................................................................................................................................................................... 243
35 -11.200sp|P24386|RAE1_HUMAN Rab proteins geranylgeranyltransferase component A 1 OS=Homo sapiens GN=CHM PE=1 SV=3  ali   22  1MADTLPSEFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRS------YYGGNWASFSFSG.......................................................................................................................................................................................................................................................................................................................................................................................................................................... 54
36 -11.200sp|Q86VQ6|TRXR3_HUMAN Thioredoxin reductase 3 (Fragment) OS=Homo sapiens GN=TXNRD3 PE=1 SV=3  ali   11  38LQEDLAYDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVG-----------IPKKLMHQAALLGQALCDSRKFGWEYNQQVRHNWETMTKAIQNHISSLYRLSLREKAVAYVNSYGEF---VEHHKIKATNKKGQETYYTAAQFVIATGERPRY......................................................................................................................................................................................................................................................................................................................... 200
37 -11.100sp|Q9NWM0|SMOX_HUMAN Spermine oxidase OS=Homo sapiens GN=SMOX PE=1 SV=1  ali follow..  11  17RGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFDVTVLEASSHIKLGHATFELGATWIHGSHGYHLAEANGLLEETTDGERSVGVACYLTNHGRRIPKDVVEEFSDLYHIIPSGFMRVVELLAEGIPAHVIQLGKPVRCIEDEQWSVVVECEDCELIPADHVIVTVSLGVLKRQYTSFFRPGLPTEKVAAIHRGTTD-EDEAESHTLTYPPELWYRKICGFDVLYPPERYGHVLSGWICGEEALVMEKCDDEAVAEICTEMLRQFTGSYTQVGSSGADVEKLAKPLPYTESSKT-APMQVLFSGEATHRKYYSTTHGA-SGQREAARLIEMYRDLFQQ..................................................................................................................................................... 553
38 -11.000sp|P31512|FMO4_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 4 OS=Homo sapiens GN=FMO4 PE=2 SV=3  ali follow..  15  2.......AKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDI--------------------------GLESSKDGMTRVYKSLVTNVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFD--YIQFKTTVCSITKRPDFDVVTETEGKQNRAVFDAVMVCTGHFLNPH------PLEAFPGIHKFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTG.................................................................................................................................................................................................................................................... 217
39 -10.900sp|Q16134|ETFD_HUMAN Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens GN=ETFDH PE=1 SV=2  ali   9  9..............................................................................................................................................................................................................................LYHLNEGEPLVALGLVVGLDYQNPYLSPFREFQRWKHH-----PSIRPTLEGGKRIAYGARAL-GFQSIPKLTFPGGLLIGCSPGFMNVPKIKGTHTAMKSGILAAESIFNQENLQSKTIGLHVTEYEDNLKN................................................................................................................................... 141
40 -10.900sp|Q8NB78|KDM1B_HUMAN Lysine-specific histone demethylase 1B OS=Homo sapiens GN=KDM1B PE=1 SV=3  ali   19  225LLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIRVWDDKSFKGVTVGRGAQIVNGCIN.................................................................................................................................................................................................................................................................................................................................................................................................................................. 294
41 -10.800sp|Q6QHF9|PAOX_HUMAN Peroxisomal N(1)-acetyl-spermine/spermidine oxidase OS=Homo sapiens GN=PAOX PE=1 SV=3  ali   12  1MESTAPGGPRVLVVGGGIAGLGAAQRLCGHFPHLRVLEATARARCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSYASSGTSVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGE......................................................................................................................................................................................................................................................................................................................................................... 157
42 -10.600sp|Q01740|FMO1_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 1 OS=Homo sapiens GN=FMO1 PE=2 SV=3  ali follow..  14  2.......AKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSDDL--------------------------GLEHVEEGRASLYKSVVSNSCKEMSCYSDFPFPEDYPNYVPNSQFLEYLKMYANHFD--HIQFKTKVCSVTKCSDSEVVTMHEEKQESAIFDAVMVCTGFLTNPY------PLDSFPGINAFKGQYFHSRQYKHPDIFKDKRVLVIGMGNSGTDIAVEASHLAEKVFLSTTGG.................................................................................................................................................................................................................................................... 217
43 -10.500sp|Q96NN9|AIFM3_HUMAN Apoptosis-inducing factor 3 OS=Homo sapiens GN=AIFM3 PE=1 SV=1  ali   17  37PSAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRIYDRPKALRPKEFFRAYGIEVLTEAQNVFTIRTPEDANRVVRLARGRNVVVVGAG-GMEVAAYLTEKAHSVSVVELEEFRRFLLMKMFENNRVKFYMQTEVSELRGQEGKLKVVLKSSK--VVRADVCVVGIGAVPATG........................................................................................................................................................................................................................................................................................................................ 284
44 -10.300sp|Q5VYX0|RNLS_HUMAN(removed signalp:1-17) Renalase OS=Homo sapiens GN=RNLS PE=2 SV=1  ali follow..  10  1.....................ALLRRQTSGPLYLAVWDKAEDSRMTTACSPHNPQCTADLGAQYITCTPHYAKKHQRFYDELLAYGVLRPLSSPIEGMVMKEGDCNFVAPQG--ISSIIKHYLKESGAEVYFRHRVTQINLRDDKWEVSKQTGSPEQFDL-IVLTMPVPEILQRQQLEASYSSRYALGLFYEAGTKIDVPWAGQYITSNPCIRFVSIDNKKRNIESSEIGPSLVIHTTVPFGVTYLEHSIEDVQELVFQQLENILPGLPQPIATKCQKWRHSQVTNAAANCPG-HKPFLACGGDG------FTQSNFDGCITSALCVLEALKNY........................................................................................................................................................ 324
45 -10.200sp|Q12882|DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2  ali   15  31.KMSEAYSAKIALFGAGPASISCASFLARLGYDITIFEKQEYVGGLSTSEIPQFRLDVVNFEIELMKDLGVKIIC--------GKSLSVNEMTLSTLKEKGYKAAFIGIGLPEPNKDAIFQGLTQDQGFYTSKDFLPLVAKGSKAGMCACHSPLPSIRGVVIVLGADCATSALR........................................................................................................................................................................................................................................................................................................................ 203
46 -10.200sp|Q16881|TRXR1_HUMAN Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens GN=TXNRD1 PE=1 SV=3  ali   11  6.DLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNY---------GWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQF-IGPHRIKATNNKGKEKIYSAERFLIATGERPRY......................................................................................................................................................................................................................................................................................................................... 167
47 -9.620sp|Q9BRQ8|AIFM2_HUMAN Apoptosis-inducing factor 2 OS=Homo sapiens GN=AIFM2 PE=2 SV=1  ali follow..  9  1MGSQVSGALHVVIVGGGFGGIAAASQLQALNVPFMLVDMKDSFHHNVAALRASVETGFAKKTFISYSVTFKDNFRQGVGIDLKNQMVLLQGGEALP----------------------FSHLILATGSTGPFPGKFNEVSSQQAAIQAYEDMVRQVQRSRFIVVGSAGVEMA-QVALADKELLPSVRQEVKEILLRKGVQLLLSERVSNLEELPLNEYREYIKVQTDKGTEVATNLVILCTGIKINSSAYRKAFESRLAS---------------------SGALRVNEHLQVEGHSNVYAIGDCADVRTPKMAY---LAGLHANIAVANIVNSVKQ--RPLQAYKPGALTFLLSM.................................................................................................................................. 332
48 -9.480sp|Q96NN9|AIFM3_HUMAN Apoptosis-inducing factor 3 OS=Homo sapiens GN=AIFM3 PE=1 SV=1  ali   9  188.SAGYSSSTNVLIVGAGAAGLVCAETLRQEGFSDRI-------------------VLCTLDRHLPYDRPKLSKSLDT-------------------------QPEQLALRPKEFF--------RAYGIEVLTEAQVVTVDVRTKKVVF--KDGF--KLEYSKLLLAPGS............................................................................................................................................................................................................................................................................................................................. 299
49 -9.380sp|Q9Y236|OSGI2_HUMAN Oxidative stress-induced growth inhibitor 2 OS=Homo sapiens GN=OSGIN2 PE=2 SV=1  ali follow..  11  9LLEDSSVTFPVVIIGNGPSGICLSYMLS--GLNSKLEEARHLSIVDQDLEYLSADFGYDYPSVKLEQHHYIPHVVLGKG-PPGGAWHNMEGSMLTISFGSWMELPGLKFMPEEIARYYKHYVKVMGQKNFRENTYITSVSRLYRD-RIADGSHVPFCLFAENVALATGTLDSPAHLEIEGEDFPFVFHSMPE-----AAINKGKLRGKVDPVLIVGSGLTAADAVLCAYNSNIPVIHVFRRRVTDPSLIFKQLPKKLYPEYHKVYHMMCTQSYSVDSNLLSDYTSFPEHRVLSFKSDMKCVLGLKLSAAVVLIGSHPNLSFLKDQGCYQPITCKGNPVEIDTYTYECIKEANLFALGPLV.............................................................................................................................. 466
50 -9.360sp|Q12882|DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2  ali   19  181.KMSEAYSAKIALFGAGPASISCASFLARLGYDITIFEKQEYV--------------------------GLS----------------------------TSEIPQFRLPYDVVNFEI--ELMKDLGVKIICGKSLSVNEMTLSTL---------KEKGYKAAFIGIGLPEPNKDAIFQGLTQD.............................................................................................................................................................................................................................................................................................................. 300
51 -9.240sp|O95831|AIFM1_HUMAN Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens GN=AIFM1 PE=1 SV=1  ali   19  143LEKISREVKSITIIGGGFLGSELACALGRKGTEVIQLFPEKGNMGKILPEYLSN---------------------------------------------------------------WTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGR--KVETDHIVAAVGLEPNVE........................................................................................................................................................................................................................................................................................................................ 255
52 -9.210sp|O95831|AIFM1_HUMAN Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens GN=AIFM1 PE=1 SV=1  ali   20  1........KSITIIGGGFLGSELACALGRKGTEVIQLFPEKGNMGKILPEYLSN---------------------------------------------------------------WTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGR--KVETDHIVAAVGLEPNVE........................................................................................................................................................................................................................................................................................................................ 105
53 -9.190sp|P50336|PPOX_HUMAN Protoporphyrinogen oxidase OS=Homo sapiens GN=PPOX PE=1 SV=1  ali follow..  11  2.......GRTVVVLGGGISGLAASYHLSRAPPKVVLVESSERL-IRSVRGPNGAIFELGPRGLLLVSELGLDSEVLPV----------RGDHPAAQNRFLYVGGALHALPTGLRGLLRPSPPFSKPLFWAGLRELTKPRGKEPDETVHSFAQRRLGPEVASLAMDSRGVFASIRSCFPSLFQAEQTHRSILLGLLLGAGRTPQPD-----------------------------------SALIRQALAERWSQWSLRGGLEMLPQALETHLTSRGVSVLRGQPVCGLSLQAE-SLRDSSLEADHVISAIP------------ASVLSELLPAEAAPLARALSAIT............................................................................................................................................ 310
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.