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Query: sp|P04424|ARLY_HUMAN Argininosuccinate lyase OS=Homo sapiens GN=ASL PE=1 SV=4, from H.sapiens

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQALast
1 -140.000sp|P04424|ARLY_HUMAN Argininosuccinate lyase OS=Homo sapiens GN=ASL PE=1 SV=4  ali  100  1MASESGKLWGGRFVGAVDPIMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHGLDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWMRQTCSTLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIAGNPLGVDRELLRAELNFGAITLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLSDAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTMSAVLQVATGVISTLQIHQENMGQALSPDMLATDLAYYLVRKGMPFRQAHEASGKAVFMAETKGVALNQLSLQELQTISPLFSGDVICVWDYGHSVEQYGALGGTARSSVDWQIRQVRALLQAQQA 464
2 -86.500sp|P30566|PUR8_HUMAN Adenylosuccinate lyase OS=Homo sapiens GN=ADSL PE=1 SV=2  ali follow..  14  17........LASRYASPE-------MCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLEN-IDFKMAAEEEKRLRHDVMAHVHT-FGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFEGDDHKVEQLDKMVKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKE-MEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGIERIQVDAYFSPIHSQLDHLLDPSSFT-------GRASQQVQRFLEEEVYPLLKPYE 473
3 -72.000sp|P07954|FUMH_HUMAN(removed signalp:1-23) Fumarate hydratase, mitochondrial OS=Homo sapiens GN=FH PE=1 SV=3  ali follow..  13  37LKVPNDKYYGAQTVRSTMN-FKIGGVTERMPTPVIKAFGILKRAAAEVNQDYGLDPKIANAIMKAAWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGNTRIGFAEKVAAKVAALTGLAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLDASVSFTENCVVGIQANTERINKLMNESLLVTALNPHI---------GYDKAAKIAKTAHKNGSTLKETAIEL----GYLTAEQFDEWVKPKDMLGPK........................... 487
4 -6.300sp|Q9NR71|ASAH2_HUMAN(removed signalp:1-36) Neutral ceramidase OS=Homo sapiens GN=ASAH2 PE=1 SV=2  ali   10  2.........................................................................................................................................................VILSGTH-THSGPAGYFQYTVQTFQHMVTGIKSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSERARYSSNTDKEMIVLKMVDLNGDDLGLISWFAIHPVSMNNSNHLVNSDNVGYASYLLEQEKNKGYLPGQGPFVAA-FASSNLGDV................................................................................................................................................................. 167
5 -6.220sp|Q9NR71|ASAH2_HUMAN(removed signalp:1-36) Neutral ceramidase OS=Homo sapiens GN=ASAH2 PE=1 SV=2  ali   12  61.....................................................................................................QNFSGYHIGVGRADCTGILTRLYSRNRTVFVSIDIGMVSQRLRLEVLNRRDNVILSGTH-THSGPAGYFQYTVQTFQHMVTGIKSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSERARYSSNTDKEMIVLKMVDLNGDDLGLISWFAIHPVSMNNSNHLVNSDNVGYASYLLEQEKNKGYLP................................................................................................................................................................................... 300
6 -5.900sp|P0C7U2|ASA2C_HUMAN Putative neutral ceramidase C OS=Homo sapiens GN=ASAH2C PE=2 SV=1  ali   11  7........................................................................................................................................SEWRSDVLNRLQSKRDNVILSGTH-THSGPAGYFQYTVQTFQHMVTGIKSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSERARYSSNTDKEMIVLKMVDLNGDDLGLISWFAIHPVSMNNSNHLVNSDNVGYASYLLEQEKNKGYLPGQGPFVAA-FSSSNLGDV................................................................................................................................................................. 195
7 -5.340sp|Q9H367|CN057_HUMAN Uncharacterized protein C14orf57 OS=Homo sapiens GN=C14orf57 PE=2 SV=1  ali follow..  17  11.........................................................................................................................ALKLRRRTVLAGQEISYVLPVMFVVSEEDSNRLVAGYRHLE------FGERIAIWGSSMQHVERRLDSIQKRMGQSFTGWAEEAAPGMKTKKEYAE....................................................................................................................................................................................................................................................... 106
8 -5.220sp|Q6ZRQ5|MMS22_HUMAN Protein MMS22-like OS=Homo sapiens GN=MMS22L PE=1 SV=3  ali   14  42................................................FSGESYLCSGALKRLILNLDPLPTNFEEDTLEI-NSSRELFHLFRQQLYNLETLLQSSCDFGKVSTLHCKA---DNIRQQCVLFLHYVKVFIFRYLKVQNAESHVPVHPYEALEAQLPSVLIDEL----HGLLLYIGHLSELPSVNIGAFVNQNQIKLFPLDIHWLVLEILYMLGEKLKQVVYGHQFMNLASDNLTNISLFEEHCETLLCDLISLSLNRYDKVRSSE----------LMSDQCPCLCIK....................................................................................................................................................................... 294
9 -4.930sp|A2RUB6|CCD66_HUMAN Coiled-coil domain-containing protein 66 OS=Homo sapiens GN=CCDC66 PE=1 SV=4  ali   12  141...............................................................................................................CVRDPLLNPNMVKNRDRQQAILKGLSELRQGLLQKQKELESSLLPLAENQEESFGSSF....................................................................................................................................................................................................................................................................................................... 198
10 -4.670sp|Q9NSG2|CA112_HUMAN Uncharacterized protein C1orf112 OS=Homo sapiens GN=C1orf112 PE=1 SV=1  ali   11  17.....................................................................................SQVLPKTVKLFDDMMYELTSQARGLSSQNLEIQTTLRNILQT-MVQLLGALTGCVQHICATQES-LHIIKSTFVHCKNSESV--------YSGCLHLVSDLLQALFKEAYS----------------QKQLMELLD-MVCMDPLVDDNDDILNMVIVIHSLLDICSVISSM--DHAFHANTWKFIIKQSLKHQS-------KSQLKHKDIITSLCEDILFSFHSCLQLAEQMTQSDAQD-NADYRLFQKTLKLCRFFANSLLHYAKEFLPFLSDSCCTLHQLYL............................................................................................... 279
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 9 4 0   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Igarashi Y, Eroshkin A, Gramatikova S, Gramatikoff K, Zhang Y, Smith JW,Osterman AL, Godzik A. CutDB: a proteolytic event database. Nucleic Acids Res. 2007 Jan;35(Database issue):D546-9. Epub 2006 Nov 16.