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Query: sp|P07954|FUMH_HUMAN(removed signalp:1-23) Fumarate hydratase, mitochondrial OS=Homo sapiens GN=FH PE=1 SV=3, from H.sapiens

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst SAPGLGGAAVPSFWPPNAARMASQNSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQDYGLDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPKLast
1 -128.000sp|P07954|FUMH_HUMAN(removed signalp:1-23) Fumarate hydratase, mitochondrial OS=Homo sapiens GN=FH PE=1 SV=3  ali  100  1SAPGLGGAAVPSFWPPNAARMASQNSFRIEYDTFGELKVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQDYGLDPKIANAIMKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKIPVHPNDHVNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLGPK 487
2 -72.000sp|P04424|ARLY_HUMAN Argininosuccinate lyase OS=Homo sapiens GN=ASL PE=1 SV=4  ali follow..  13  1....................................MASESGKLWGGRFVGAVDPMEKFNASIAYDRHLWEVDVQGSKAYSRGLEKAGLLTKAEMDQILHG----------------LDKVAEEWAQGTFKLNSNDEDIHTANERRLKELIGATAGKLHTGRSRNDQVVTDLRLWMRQTC-STLSGLLWELIRTMVDRAEAERDVLFPGYTHLQRAQPIRWSHWILSHAVALTRDSERLLEVRKRINVLPLGSGAIA---GNPLGVDRELLRAELNFGAI----TLNSMDATSERDFVAEFLFWASLCMTHLSRMAEDLILYCTKEFSFVQLS--DAYSTGSSLMPQKKNPDSLELIRSKAGRVFGRCAGLLMTLKGLPSTYNKDLQEDKEAVFEVSDTM-SAVLQVATGVISTLQIHQENMGQALSPDM-LATDLAYYLAHEASGKAVFMAETKGVALNQLSLQESPLFSGDVICVWDYGHSVEQY 437
3 -65.700sp|P30566|PUR8_HUMAN Adenylosuccinate lyase OS=Homo sapiens GN=ADSL PE=1 SV=2  ali follow..  16  1....................MAAGGDHGSPDSYRS----PLASRYASPEMCFV----------FSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKS-----------------NLENIDFKMAAEEEKRLRHDVMAHVHTF-GHCCPKAAGIIHLGATSCYVGDNTDLIILRNAL-DLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKG-TTGTQASFLQLFE-GDDHKVEQLDKMVFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLAN--LKEMEEPF-EKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATGSRQDCHEKIRVLSQQAASVVKQEGGDVDAYFSPIHSQLDHLLDPSSFTG.. 451
4 -7.240sp|Q9C010|IPKB_HUMAN cAMP-dependent protein kinase inhibitor beta OS=Homo sapiens GN=PKIB PE=2 SV=1  ali follow..  7  1...........................................................................................................................................................................................MRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALS....................................................................................................................................................................................................................................................... 53
5 -6.600sp|P61925|IPKA_HUMAN cAMP-dependent protein kinase inhibitor alpha OS=Homo sapiens GN=PKIA PE=1 SV=2  ali follow..  19  1..................................................................................................................................................................................................MTDVETTYADFIASGRTGRRNAIHDILVSSASGNSNELALKLAGLD....................................................................................................................................................................................................................................................... 46
6 -6.510sp|Q9Y2B9|IPKG_HUMAN cAMP-dependent protein kinase inhibitor gamma OS=Homo sapiens GN=PKIG PE=1 SV=1  ali follow..  19  1..................................................................................................................................................................................................MMEVESSYSDFISCDRTGRRNAVPDIQGDSEAVSVRKLAGDMGELA....................................................................................................................................................................................................................................................... 46
7 -5.140sp|Q8WXX0|DYH7_HUMAN Dynein heavy chain 7, axonemal OS=Homo sapiens GN=DNAH7 PE=1 SV=2  ali   9  3................................................................................................................................................................SKSKPTTLKPIILNEIVDAHKEKIKEVIMKESVAPTEHLRLYDKYDFLITRKAERDVDNFLAEN----YEKIIDEICKYQKLIEEIQYTSIKTIRLGMFEMHCEELIRALVKRADIICGKLLAKMFRDH-----QEVNTRLCDEFERIAEKALSTPPNT-----AELMEMKAYI------------QKVEVTDMIELEQRLVDSKNCLAFLIEYVNFSPADMRLNNSVFQWRMGEIFEEHRKIIKEKIEQYQEGLKLRCERFVEELESYAKQSEEFYSFGDLQDVQRYLKKAQILNGKLDLAADKIEQFNAEEEAFGWLP....... 300
8 -5.080sp|Q8TE73|DYH5_HUMAN Dynein heavy chain 5, axonemal OS=Homo sapiens GN=DNAH5 PE=1 SV=3  ali   9  17...................................................................................................................................................................ARNQPPIAGKILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQIEEIHVGVKAPGTGELFVNFDPQIL------------ILFRETECMAQMGLEVSPLATSLFQKRDRYKRNFSNMKMMLAEYQRVKSKIEQLIVPHLAKVDEALQP----GLAAL---TSLNIEAYLENTFAKIKDLELLLDRVNDLIEFRIDAILEEMSSTPL-TCEEFLQMTKDLCVNGAQILHFKSSLVEEAVNELVNMLLDVEVLSEEE............................................ 297
9 -4.830sp|Q01546|K22O_HUMAN Keratin, type II cytoskeletal 2 oral OS=Homo sapiens GN=KRT76 PE=1 SV=2  ali   17  1........................................................................................................................................................................................QTALQKAKDDLARLLRDYQELM----------VKLALDVEIATYRKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSG................................................................................................................................................................................................................................ 70
10 -4.800sp|P12035|K2C3_HUMAN Keratin, type II cytoskeletal 3 OS=Homo sapiens GN=KRT3 PE=1 SV=3  ali   21  4..........................................................................................................................................................................EMALKDANAKLQELQAALQQAKDDLARLLRDYQELM----------VKLALDVEIATYRKLLEGEEYRMS....................................................................................................................................................................................................................................................... 64
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Harder T, Kolodny R, Sitbon E, Li Z, Godzik A. Using an alignment of fragment strings for comparing protein structures. Bioinformatics. 2007 Jan 15;23(2):e219-24.