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Query: sp|P49326|FMO5_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 5 OS=Homo sapiens GN=FMO5 PE=2 SV=2, from H.sapiens

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWRFQENPEEGRASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHNAQVLEYFRMYAKEFDLLKYIRFKTTVCSVKKQPDFATSGQWEVVTESEGKKEMNVFDGVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDDIDAVIFATGYSFDFPFLEDSVKVVKNKISLYKKVFPPNLERPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKTLPSQSEMMAEISKAQEEIDKRYVESQRHTIQGDYIDTMEELADLVGVRPNLLSLAFTDPKLALHLLLGPCTPIHYRVQGPGKWDGARKAILTTDDRIRKPLMTRVVERSSSMTSTMTIGKFMLALAFFAIIIAYFLast
1 -130.000sp|P49326|FMO5_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 5 OS=Homo sapiens GN=FMO5 PE=2 SV=2  ali  100  1MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGGLWRFQENPEEGRASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHNAQVLEYFRMYAKEFDLLKYIRFKTTVCSVKKQPDFATSGQWEVVTESEGKKEMNVFDGVMVCTGHHTNAHLPLESFPGIEKFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGNVKEFTETAAIFEDGSREDDIDAVIFATGYSFDFPFLEDSVKVVKNKISLYKKVFPPNLERPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKTLPSQSEMMAEISKAQEEIDKRYVESQRHTIQGDYIDTMEELADLVGVRPNLLSLAFTDPKLALHLLLGPCTPIHYRVQGPGKWDGARKAILTTDDRIRKPLMTRVVERSSSMTSTMTIGKFMLALAFFAIIIAYF 533
2 -125.000sp|P31513|FMO3_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 3 OS=Homo sapiens GN=FMO3 PE=1 SV=5  ali follow..  52  2..GKKVAIIGAGVSGLASIRSCLEEGLEPTCFEKSNDIGGLWKFSDHAEEGRASIYKSVFSNSSKEMMCFPDFPFPDDFPNFMHNSKIQEYIIAFAKEKNLLKYIQFKTFVSSVNKHPDFATTGQWDVTTERDGKKESAVFDAVMVCSGHHVYPNLPKESFPGLNHFKGKCFHSRDYKEPGVFNGKRVLVVGLGNSGCDIATELSRTAEQVMISSRSGSWVMSRVWDNGYPWDMLLVTRFGTFLKNNLPTAISDWLYVKQMNARFKHENYGLMPLNGVLRKEPVFNDELPASILCGIVSVKPNVKEFTETSAIFEDGTIFEGIDCVIFATGYSFAYPFLDESIIKSRNNEILFKGVFPPLLEKSTIAVIGFVQSLGAAIPTVDLQSRWAAQVIKGTCTLPSMEDMMNDINEKMEKKRKWF--GKSETIQTDYIVYMDELSSFIGAKPNIPWLFLTDPKLAMEVYFGPCSPYQFRLVGPGQWPGARNAILTQWDRSLKPMQTRVVGRLQKPCFFFHWLKLFAIPILLIAVFLVL 531
3 -125.000sp|Q99518|FMO2_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 2 OS=Homo sapiens GN=FMO2 PE=1 SV=3  ali follow..  55  2..AKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGVWRFKENVEDGRASIYQSVVTNTSKEMSCFSDFPMPEDFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDFSSSGQWKVVTQSNGKEQSAVFDAVMVCSGHHILPHIPLKSFPGMERFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRISEDGYPWDSVFHTRFRSMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLCGAIKVKSTVKELTETSAIFEDGTVEENIDVIIFATGYSFSFPFLEDSLVKVNNMVSLYKYIFPAHLDKSTLACIGLIQPLGSIFPTAELQARWVTRVFKGLCSLPSERTMMMDIIKRNEKRIDLFGESQSQTLQTNYVDYLDELALEIGAKPDFCSLLFKDPKLAVRLYFGPCNSYQYRLVGPGQWEGARNAIFTQKQRILKPLKTRALKDSSNFSVSFLLKILGLLAVVVAFFCQL. 532
4 -123.000sp|Q01740|FMO1_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 1 OS=Homo sapiens GN=FMO1 PE=2 SV=3  ali follow..  51  2..AKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSDDLGGLWRFTEHVEEGRASLYKSVVSNSCKEMSCYSDFPFPEDYPNYVPNSQFLEYLKMYANHFDLLKHIQFKTKVCSVTKCSDSAVSGQWEVVTMHEEKQESAIFDAVMVCTGFLTNPYLPLDSFPGINAFKGQYFHSRQYKHPDIFKDKRVLVIGMGNSGTDIAVEASHLAEKVFLSTTGGGWVISRIFDSGYPWDMVFMTRFQNMLRNSLPTPIVTWLMERKINNWLNHANYGLIPEDRTQLKEFVLNDELPGRIITGKVFIRPSIKEVKENSVIFNNTSKEEPIDIIVFATGYTFAFPFLDESVVKVDGQASLYKYIFPAHLQKPTLAIIGLIKPLGSMIPTGETQARWAVRVLKGVNKLPPPSVMIEEINARKENKPSWFGLCYCKALQSDYITYIDELLTYINAKPNLFSMLLTDPHLALTVFFGPCSPYQFRLTGPGKWEGARNAIMTQWDRTFKVIKARVVQESPSPFESFLKVFSFLALLVAIFLIFL. 532
5 -122.000sp|P31512|FMO4_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 4 OS=Homo sapiens GN=FMO4 PE=2 SV=3  ali follow..  51  2..AKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVTNVCKEMSCYSDFPFHEDYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFSETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCCSFIAQVLPSRFLNWIQERKLNKRFNHEDYG-LSITKGKKAKFIVNDELPNCILCGAITMKTSVIEFTETSAVFEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSCTKKIFLYKQVFPLNLERATLAIIGLIGLKGSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATEKEQLIKRGV-FKDTSKDKFDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLMGPGKWDGARNAILTQWDRTLKPLKTRIVPDSSKPASMSHYLKAWGAPVLLASLLLIC 531
6 -119.000sp|O60774|FMO6_HUMAN(removed signalp:1-17) Putative dimethylaniline monooxygenase [N-oxide-forming] 6 OS=Homo sapiens GN=FMO6P PE=5 SV=1  ali follow..  48  1..................IWCCLEEGLEPTCFERSDDVGGLWKFSDHTEEGRASIYQSVFTNSSKEMMCFPDFPYPDDYPNYIHHSKLQEYIKTYAQKKDLLRYIQFETLVSGIKKCPSFLVTGQWVVVTEKDGKQESTIFDAVMICSGHHVYPNLPTDSFPGLDQFRGNYLHSRDYKNPEAFKGKRVLVIGLGNSGSDIAVELSRLATQVIISTRSASWVMSRVWDDGYPWDMMYVTRFASFLRNVLPSFISDWLYVQKMNTWFKHENYGLMPLNGSLRKEPVFNDELPSRILCGTLSIKPSVKEFTETSAVFEDGTMFEAIDSVIFATGYDYSYPFLDETIMKSRNNETLFKGIFPPLMEKPTLAVIGLVQSLGAAIPTADLQAWWAAKVFANSCTLPTTNEMMDDTDEKMGKKLKFFMFGQSQTLQTDYITYVDELGSFIGAKPNIPWLFLTDPRLALEVYFGPCSPYQFRLMGPGKWDGARNAILTQWNRTVKPTRTRVVSEVQRPHPFYNLLKMLSFPLLLLAVTLTF 521
7 -42.600sp|Q8IWF2|FXRD2_HUMAN(removed signalp:1-26) FAD-dependent oxidoreductase domain-containing protein 2 OS=Homo sapiens GN=FOXRED2 PE=1 SV=1  ali   19  3.PRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFERAPRPGSFFTRYPSINKRYTGKANAEFNLRHDWNSLLSHDP-HYSRAYFPDARDMVRYLGDFADTLGL--RVQYNTTIAHVTLDKD---RQAWNGHYLTDQKGQVHQCSVLFVATG-LSVPNQV--DFPGSEYAEG---YESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSWA..................................................................................................................................................................................................................................................................................................................... 226
8 -42.000sp|Q8IWF2|FXRD2_HUMAN(removed signalp:1-26) FAD-dependent oxidoreductase domain-containing protein 2 OS=Homo sapiens GN=FOXRED2 PE=1 SV=1  ali   16  2...............................................................................................................................................LFVATG-LSVPNQV--DFPGSEYAEGYESVSVDPED---FVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSWATHYVG-DLRAINNGLLDTYQLKSLDGLLESDLTDLAI------------------LKDSKGKFHVTPKFFLEEANTNQSADSITLPQDDNDNFAMRVPYDRVIRCLGWNFDFSIFNKSLRLNSGNAF--IRASYESKGSRGLFILGTAKSAGGFIHGFRYTVRAVHRLLEHRHHSVTWPATELPITQLTSSIVRRVNEASGLYQMFGV------LADVILLKENSTAFEYLE............................................................................. 294
9 -40.200sp|Q9Y236|OSGI2_HUMAN Oxidative stress-induced growth inhibitor 2 OS=Homo sapiens GN=OSGIN2 PE=2 SV=1  ali follow..  11  91TLLHPDADFGYDYPSVLHWKLEQHHYIPHVVLGKGP-PGGAW----------HNMEGSMLTISFGSWMELPGLKFKDLKGDRVMPEEIARYYKHYVKVMGLQKNFRENTYITSVSRLYRDFIKRNWEIRGDGSHVPFCLFAENVALATGTLDSPAHL--EIEGEDFHSMPEFGAAINKGKLRGKVDPVLIVGSGLTAADAVLCAYNSNIPVIHVFRRRVTDPSLIFKQLPKKLYPEYHKVYHMMCTQSY----------------------SVDSNLLSDYTSFPEHRVLSFKSDMKCVLQSV-----------SGLKKIFKLSAAVVLIGSHPNLSFLKDQGCYLGHKSSQPITCKGNPVKEANLFALGPLVG-DNFVRFLKGGALGVTRCLATRQKKKHLFVERGGGDG.......................................................................................................................... 503
10 -37.500sp|Q9UJX0|OSGI1_HUMAN Oxidative stress-induced growth inhibitor 1 OS=Homo sapiens GN=OSGIN1 PE=2 SV=2  ali follow..  12  98.EPLPVIIVGNGPSGICLSYLLKEHAIPHVVLGRNL-PGGAWH----------SIEGSMVILSQGQWMGLPDLEVKDLRNSRATAGDIAHYYRDYVVKKGLGHNFVSGAVVTAVEWGTPDDSSPLFQVSRNQAQQPFSLWARNVVLATGTFDSPARLGIPGEALPFHELSALEAATRVGAVTPASDPVLIIGAGLSAADAVLYARHYNIPVIHAFRRAVDDPGLVFNQLPKMLYPEYHKVHQMMREQ-----------------------SILSPSPYEGYRSLPRHQLLCFKEDCQAVFQDL-----------EGVEKVFGVSLVLVLIGSHPDLSFLPGAGADFAVDPDQPLSAK--STRQEGLYAMGPLAG-DNFVRFVQGGALAVASSLLRKET-P..................................................................................................................................... 560
11 -20.600sp|Q12882|DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2  ali   17  36.YSAKIALFGAGPASISCASFLARLGYDITIFEKQEYVGGLSTS---------------------------------EIPQFRLPYDVVNFEIELMKDLGV--KIICGKSL----------------VNEMTLSTLKEKGYKAAFIGIGLPEPNKDAIFQ--GLTQDQG-FYTSKDFHSPLPSIRGVVIVLGAGDTAFDCATSALRCARRVFIVFRKGFVNIR----------------------------------------AVPEEMELAKEEKCEFLPFLSPRKVIVKGGRIVAMQFVRTEQDETGKWNEDEDQMVHLKADVVISAFGSVLSDPKVKEA............................................................................................................................................................................................... 300
12 -17.700sp|P22570|ADRO_HUMAN(removed signalp:1-24) NADPH:adrenodoxin oxidoreductase, mitochondrial OS=Homo sapiens GN=FDXR PE=1 SV=3  ali follow..  13  13.KTPQICVVGSGPAGFYTAQHLLKHQAHVDIYEKQPVPFGLVRFG---------------------------------APDHPEVKNVINTFTQTAHS----GRCAFWGNV---------------EVGRDVTVPELREAYHAVVLSYGAEDHRALEIPG----EELPG-VCSARAFELEPDLSCDTAVILGQGNVALDVARILLTPPEHVWLVGRRGPLQVAREMIQLPGARPILDPVDFLGLQDKIKEVPRPRKRLTELLLRTATEKPGPAEAARQASAQQVLPSPDGRRAAGVRLAVTRLEGVDEATRAVPTGDMEDLPCGLVLSSIGYK-SVPFDSKLGVIPNVEGRV--------MDVPGLYCSGWVKR-TGVIATTMTDSFLTGQMLLQDLK---AGLLPSGPRPGYAAIQALLSSRGVRPVSFSDWEKLDAEEVARGQGTGKPREKLVDPQEMLRLL..................................................................... 465
13 -15.700sp|Q9BRQ8|AIFM2_HUMAN Apoptosis-inducing factor 2 OS=Homo sapiens GN=AIFM2 PE=2 SV=1  ali follow..  10  10.GALHVVIVGGGFGGIAAASQLQALNVPFMLVDMKDSF----------------NVAALRASVETGFAKKTFISYSV-----------------------TFKDNFRQGLVVGIDLKNQ-------MVLLQGGEALP---FSHLILATGS----TGPFPGKFNEVSSQQAAIQAYEDMVRQVQRSRFIVVVGGGSAGVEMAAEIKTEYPEKEVTLIHSQ-------------VALADKELLPSVRQEVKEILLRKGVQLLLSERVS------------------------------NLEELPLNEYREYIKVQTDKGTEV-ATNLVILCTGIKINSSAYRKAFESRASSGALRVNEHLQVEGHSNVYAIGDCADVRKMAYLAGLHANIAVANIVNSVKQRPLQAYK............................................................................................................................... 322
14 -15.100sp|P00390|GSHR_HUMAN Glutathione reductase, mitochondrial OS=Homo sapiens GN=GSR PE=1 SV=2  ali follow..  14  62VASYDYLVIGGGSGGLASARRAAELGARAAVVES-HKLGGT---------NVGCVPKKVMWNTAEFMHDHADYGFPSCEGKF-NWRVIKEKRDAYVSRLN-YQNNLTKSHIEIIRGHAAFTSDPKPTIEVSG----KKYTAPHILIATG--GMPSTPESQIPGASL----GITSDGFFQLEEL--GRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVL--------RSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLE-----------------------------------VSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVV---------IHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR............... 522
15 -14.100sp|Q16881|TRXR1_HUMAN Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens GN=TXNRD1 PE=1 SV=3  ali   13  15.....LIIIGGGSGGLAAAKEAAQYGKKVMVLDFRWGLGGT---------NVGCIPKKLMHQAALLGQALQDYGWKVEETVKHDWDRMIEAVQNHIGSLN-YRVALREKKVVYENAYGQFIGPHRIKAT-NNKGKEKIYSAERFLIATGE-------RPRYLGIPGDKEYCISSDDLFSLPYC--GKTLVVGASYVALECAGFLAGIGLDVTVMVRS---------------------ILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTN-----------------------SEEIIEGEYNTVMLAIGRDACTRKI.................................................................................................................................................................................................. 300
16 -14.100sp|Q86VQ6|TRXR3_HUMAN Thioredoxin reductase 3 (Fragment) OS=Homo sapiens GN=TXNRD3 PE=1 SV=3  ali   13  48.....LIIIGGGSGGLSCAKEAAILGKKVMVLDFSWGLGGT---------NVGCIPKKLMHQAALLGQALCDFGWEYNQQVRHNWETMTKAIQNHISSLN-YRLSLREKAVAYVNSYGEFVEHHKIKAT-NKKGQETYYTAAQFVIATGE-------RPRYLGIQGDKEYCITSDDLFSLPYCP-GKTLVVGASYVALECAGFLAGFGLDVTVMVRS............................................................................................................................................................................................................................................................................................................................ 255
17 -14.000sp|P09622|DLDH_HUMAN Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens GN=DLD PE=1 SV=2  ali follow..  14  44.....VTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGT---------PSKALLNNSHYYHMAHGKDFASRGIEMSEVRL-NLDKMMEQKSTAVKALGIAHLFK-QNKVVHVNGYGKITGKNQVTAT-KADGGTQVIDTKNILIATGSEVT------PFPGITIDEDTIVSSTGALSLKKVP-EKMVVIGAGVIGVELGSVWQRLGADVTAVE-----FLGHVGGVGIDME----------ISKNFQRILQKQGFKFKLNTKVTG----------------------ATKKSDGKIDVSIEAAS--------GGKAEVITCDVLLVCIGRRPFTKNLGEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVVPSVIYTHPEVAW----KSEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVL----------HILGPGAGEMVNEAALALEYGA...................................... 475
18 -14.000sp|Q96NN9|AIFM3_HUMAN Apoptosis-inducing factor 3 OS=Homo sapiens GN=AIFM3 PE=1 SV=1  ali   12  43.SSTNVLIVGAGAAGLVCAETLRQEGFS----------------------------DRIVLCTLDRHLPYDRPKLSKSLDTQPEQLALRP--KEFFRAYGI--EVLTEAQVVTVDVRTK-------KVVFKDG---FKLEYSKLLLAPG--SSPKTLSCKGKEVENVFTIRTPEDANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEE-----------TPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQE---------------------------GKL-----------KEVVLKSSKVV-RADVCVVGIGAVPATGFLRQSGIGLDSRGFIP.................................................................................................................................................................................... 300
19 -13.700sp|Q9NNW7|TRXR2_HUMAN Thioredoxin reductase 2, mitochondrial OS=Homo sapiens GN=TXNRD2 PE=1 SV=3  ali follow..  15  42.....LLVVGGGSGGLACAKEAAQLGRKVAVVDYRWGLGGT---------NVGCIPKKLMHQAALLGGLIQDYGWEVAQPVPHDWRKMAEAVQNHVKSLN-HRVQLQDRKVKYFNIKASFVDEHTVCGV-AKGGKEILLSADHIIIATG--GRPRYP----THIEGALEYGITSDDIFWLKESP-GKTLVVGASYVALECAGFLTGIGLDTTIMMRS-----------------IPLRGFDQQMSSMVIEHMASHGTRFLRGCAPSR----------------------VRRLPDGQLQVTWEDST--------TGKEDTGTFDTVLWAIGRVPDTR-LEKAGVDTSPDTQKILVDSREATSVPHIYAIGVVEGRPELTPIAIMAGRLLVQRLFGGSSVPT.................................................................................................................................... 397
20 -13.700sp|Q8WU10|PYRD1_HUMAN Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 OS=Homo sapiens GN=PYROXD1 PE=1 SV=1  ali follow..  11  9.TAGKFVVVGGGIAGVTCAEQLATHF-DILLVTASPVI--------------KAVTNFKQISKI-----------------LEEFDVEEQSSTMLGKRFPNIKVI--ESGVKQLKSEEH-------CIVTEDGNQHV---YKKLCLCAG--AKPKLICEGNPYVLGIRD--TDSAQEFQKQLTKAKRIMIIGNGGIALELVYEIEGCEVIWFFDAGAAEFLTSKLIAEK--SEAKIAHKRTRYTTEGRKKEARSKSKADNVGSALGPDWHEGLNLKGTKEFSHKIHLETMCEVKK-DHKSVTADTEMWPVYVELTNEKIY-GCDFIVSATGVTPNVEPFLHGNSFDLGEDGGLKVDDHMHTSLPDIYAAGDICTT-RLWTQARQMGWYAAKCMAAASSGDSIDMDFSFELFAHVTKFFNYKVVLLGKYNAQGLGSDHELMLRCTKGREYIKVVMQNGRMMGAVLIGETDLEE--ILNQMNLSSYGEDLLDPNIDIEDYFD................................. 500
21 -13.400sp|Q8NB78|KDM1B_HUMAN Lysine-specific histone demethylase 1B OS=Homo sapiens GN=KDM1B PE=1 SV=3  ali   11  81.HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGQIVNGCI-NNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYAC----------GSNLHQVSARSWDHNEFFAQFAGDHTLLTGYSVIIEKLAEGLDIQLKSPVQC............................................................................................................................................................................................................................................................................................................................... 300
22 -13.200sp|Q12882|DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2  ali   15  186.YSAKIALFGAGPASISCASFLARLGYDITIFEKQEYVGGLSTS---------------------------------EIPQFRLPYDVVNFEIELMKDLGV--KIICGKSL----------------VNEMTLSTLKEKGYKAAFIGIGLPEPNKDAIFQGLTQD................................................................................................................................................................................................................................................................................................................................................................................ 300
23 -12.900sp|Q8TDZ2|MICA1_HUMAN NEDD9-interacting protein with calponin homology and LIM domains OS=Homo sapiens GN=MICAL1 PE=1 SV=2  ali   13  82CTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRT---------KFSRHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISIRQLQLLLLKVALLLGVE--IHWGVTFTGLQPPPRKGSGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPE----GFKVRE-MRGK........................................................................................................................................................................................................................................................................................................................................................................... 235
24 -11.900sp|Q6QHF9|PAOX_HUMAN Peroxisomal N(1)-acetyl-spermine/spermidine oxidase OS=Homo sapiens GN=PAOX PE=1 SV=3  ali   12  1.PVPSVGEYLKKEIGQHVARLCGHSAFHLRVLEATARAGGHWIHGPSRGNPVFQLAAEYGLLGEKELSQGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVL--SGTHSMDLVALAPFGEYTVLPGLDC-MAALPEDTVVFEKPVKTIHWNGSFQEAAFP--GETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPL.............................................................................................................................................................................................................................................................................................. 292
25 -11.700sp|Q7RTP6|MICA3_HUMAN Protein MICAL-3 OS=Homo sapiens GN=MICAL3 PE=1 SV=2  ali   14  84CTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDA-------FSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAG--AIDHISIRQLQLILLKVALILGIE--IHVNVEFQGLIQPPEDERIGWRALVHPKTHPVSEYEFEVIIGGDGRRNTLE----GFRRKE-FRGK........................................................................................................................................................................................................................................................................................................................................................................... 240
26 -11.500sp|O15229|KMO_HUMAN Kynurenine 3-monooxygenase OS=Homo sapiens GN=KMO PE=1 SV=2  ali follow..  12  6IQRKKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDT-GL----EDQIVSQGIPMRARMIHSLSGKKSAIPYGTKSQYILSVSRENLNKDLLTAAEKYP---KMHFNHRLLKCNPEEGM------ITVLGSDKVPKDVTCDLIVGCDGAYSTVR-PRFDYSQQYIPHGYMELTIPPKNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCTLFMPFE-----------------------EFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKSHCVLLGDAAH--AIVPFFGQGMNAGFEDCLVFDE........................................................................................................................................................................................................... 329
27 -11.500sp|O94851|MICA2_HUMAN Protein MICAL-2 OS=Homo sapiens GN=MICAL2 PE=1 SV=1  ali   15  84CTNTKCLIVGGGPCGLRTAIELAYLGAKVVVVEKRD---------SFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILFKVALMLGVE--IHVNVEFVKVLEPPEDQKIGWRAEFLPTDHSLSEFEFDVIIGADGRRNTLE----GFRRKE-FRGK........................................................................................................................................................................................................................................................................................................................................................................... 240
28 -11.400sp|Q6QHF9|PAOX_HUMAN Peroxisomal N(1)-acetyl-spermine/spermidine oxidase OS=Homo sapiens GN=PAOX PE=1 SV=3  ali   20  12.GGPRVLVVGGGIAGLGAAQRLCGHFPHLRVLEATARAGG-------------------RIRSERCFGGVVEV------AHWIHGPSRGNPVFQLAAEYGLLGE............................................................................................................................................................................................................................................................................................................................................................................................................................................. 92
29 -11.400sp|Q9Y6N5|SQRD_HUMAN Sulfide:quinone oxidoreductase, mitochondrial OS=Homo sapiens GN=SQRDL PE=1 SV=1  ali follow..  12  42.NHYEVLVLGGGSGGITMAARMKRKAENVAIVEPSER-----------------FYQPIWTLVGAGAKQLSSSGRPTA----------------------IPSGVEWKARVTELNPDKN-------CIHTDDDEKIS---YRYLIIALGI----QLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALIFTFPNTPVKCAGAPQKIMYLSEAYFRK-----------------------------------TGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFENLDKPGETQVISYEMLHVTPPMSPP-DVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGTNLPTSKTAAAVAAQSGILDRTISVIMK....................................................................................................................................... 365
30 -11.200sp|Q96RQ9|OXLA_HUMAN(removed signalp:1-21) L-amino-acid oxidase OS=Homo sapiens GN=IL4I1 PE=1 SV=1  ali follow..  13  37.KPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGIFTYRDQNTGWIGELGAMRMPSSHRILHKLCQ-LGCRKAMKKFERHTLLEYLDLLPRALSLSGLVLLNAPVVAMTQGPHDVHV---IETSPPARNLKVLKADVVLLTKRITFSPPLPRHMQEALRRLHYVPATKVFLSFRRPFWREEHIEGGHSNTDRPSRMYPPPREGALLLAS.............................................................................................................................................................................................................................................................................................................................. 376
31 -11.200sp|Q8NBM8|PCYXL_HUMAN(removed signalp:1-22) Prenylcysteine oxidase-like OS=Homo sapiens GN=PCYOX1L PE=1 SV=2  ali follow..  16  2APPGKIAVVGAGIGGSAVAHFLQQPRVQIDVYEK-GTVGG--SVNKQHYESGAASFHSLSLHMQDFVKLLG-YKYQAHGYAFSGVEELLESLQRFIDDVLTKANVIHATVTSVTLHSTEGKAL--YQVAYENEVGNSSDFYDIVVIAT................................................................................................................................................................................................................................................................................................................................................................................................. 280
32 -11.000sp|O60341|KDM1A_HUMAN Lysine-specific histone demethylase 1A OS=Homo sapiens GN=KDM1A PE=1 SV=2  ali   30  127.KTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGG............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 165
33 -10.900sp|Q6NUM9|RETST_HUMAN(removed signalp:1-18) All-trans-retinol 13,14-reductase OS=Homo sapiens GN=RETSAT PE=2 SV=2  ali follow..  9  48.EKLDVVVIGSGFGGLAAAAILAKAGKRVLVLEQHTKAGGILDQITEGQLDWAPLSSPFDIMVLEGPNGRKEYPMYSGEKAYIQGAIIDKYIKLVKVVSSGAPHASLAEVLQQLGASSELQAVLSYIFPTYGVTPNHSAFSMHALLVNHYMKGGFYPR----GSSEIAFHTIPVIQRAGGAVLTKATVVLLDSAGKACGVSVKLVNIYCPIVVSNAGLFNTYEHLLPGNARCLPGVKQQLGTVRPGLGMTSVFICLRGTKEDLHLPSTNYYVYYDTDMDQAMERYVSMPREEAAEHIPLLFFAFPSAKDPTWE-DRFPGRSTMIMLIPTADYETFFPQLEGKVESVTAGSPLTNQFYLAQSPIPNLYLTGQDIFTCGLVGAL-QGALLCSSAILKRNLYSDLKNLDSRIRAQKKK...................................................................................................................... 591
34 -10.700sp|P27338|AOFB_HUMAN Amine oxidase [flavin-containing] B OS=Homo sapiens GN=MAOB PE=1 SV=3  ali follow..  12  1MSNKDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKSTTNGGQERKFVGGSGQVSERIMDIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFAHKARKLARLTKEERLKKLCEEKNWCEE-QYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLER.............................................................................................................. 484
35 -10.500sp|Q9UHG3|PCYOX_HUMAN(removed signalp:1-27) Prenylcysteine oxidase 1 OS=Homo sapiens GN=PCYOX1 PE=1 SV=3  ali follow..  10  6.PPDKIAIIGAGIGGTSAAYYLRQKDVKIDLFER-EEVGG--MVQGQEYEAGGSVIHPLNLHMKRFVKDLG--QASGGLLGIYNGETLVFEESNWFIINVIKLVWRYGFQSLRMHMWVEDVLDKFMRIYRYQSHDYAFSSVEKLLHALGGDDFLGMLNRTLL-------ETLQKAGFSEKEMIAPVMRVNYGQSTDINAFVGAVSLSCSD-LWAVEGGNKLVCSGLLQASKSN--------------------------------------------------LISGSVMYIEEKTKTKYTGNPTKMYEVVYQIGTETRSDFYDIVLVATPLNRKMSNITF................................................................................................................................................................................................ 299
36 -10.400sp|Q16134|ETFD_HUMAN Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens GN=ETFDH PE=1 SV=2  ali   12  71.....VVIVGAGPAGLSAAVRLKQKDIRVCLVEKAAQIGG---KEKGAPLNTPVTEDRFGILTEKYRIPVPGLPMNNHGNYIVRLGHLVSWMGEQAEALGVE--VYPGYAAAEVLFHDDGSVKG---APKATFERGLELHAKVTIFAEGCHGHLAKQLYKKFDLRANCEPQTYGIGLKELWVIDEKNWVDHTVG................................................................................................................................................................................................................................................................................................................................................... 296
37 -10.200sp|Q8N2H3|PYRD2_HUMAN Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 OS=Homo sapiens GN=PYROXD2 PE=2 SV=2  ali follow..  11  32KPEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEIIPGFKFSRASYLLSLLRPQIYTDLELPMLEEGAGSKVPRCLMAENQKQIAQFSQKDAQVFPKYEEFMHRLALAIDPLLDAAPVDMAAFQHGSLLQRMRSLSTLKPLLKAGRILGAQLPRYYEVLTAPITKVLDQWFESEPLVIGAMTSPHTPGSGYVLLHHVMGGLEGMQGAWGYVQ---GGM-----------------------------------------------------ALSDAIASSATTASIFTEKTVAKVCVQGVVLEDGTEV-RSKMVLSNTSPQITFKLTPQEWLPEEFLERISQLDTRSPVTKINVAVDRLPSFLAANCEDTLLLHQAFEDAMDGLPSAPP-EQERDAYADRVFDCIEVYAPGFKDSVVGRDILTPPDLERIFGLP----NIFHCAMSLDQLYFARPVPLHGYRLCGSGAHPGAAHVAFRDLKSM...................................... 581
38 -10.100sp|P21397|AOFA_HUMAN Amine oxidase [flavin-containing] A OS=Homo sapiens GN=MAOA PE=1 SV=1  ali follow..  12  12.HMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWY-FSVTNGGQERKFVGGSGQVSERIMDVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYK-------EAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEERAAREVLNGLGKVTE....................................................................................................................... 468
39 -10.100sp|Q8NB78|KDM1B_HUMAN Lysine-specific histone demethylase 1B OS=Homo sapiens GN=KDM1B PE=1 SV=3  ali   30  231.HNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGG............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 269
40 -10.100sp|Q9NWM0|SMOX_HUMAN Spermine oxidase OS=Homo sapiens GN=SMOX PE=1 SV=1  ali follow..  12  23.GQPRVVVIGAGLAGLAAAKALLEQGFDVTVLEASSHIGG-WYLTNHGRRIPKDVVEEFSDLYNEVYNLTQEFFRHDKPVNAESQNSVGVFTREEVRNR-IRNDPDDPEATKRLKLACESSSHSMDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPAHVIQLGKPVRCIHWDQASARPRGPEIEPRGEGDHNRGGRWDEDEQWSVVVECEDCELIPADHVIVTVSLGVLKRQYTSFFRPGL-----------------------------------PTEKVAAIHRLGIGTTDKI----------LEFEEPFWGPECNSLQFVWEDEAESHTLTYPPELWYRKICGFDVLYPPERYGHVLSICGEEALVMEKCDDEAVAEICTEMLFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYTESSKTAPMQVLFS----------GEATHRKY----YSTTHGALLSGQREAARLIEMYRDLFQQGT.......................... 555
41 -9.800sp|Q8NHU2|CT026_HUMAN Uncharacterized protein C20orf26 OS=Homo sapiens GN=C20orf26 PE=2 SV=3  ali   8  65..NAKIIVVGASSVGISFLETLVFCSNNLTLISTHG-------------------LPGKKLLDTEQRKFLAS----------------HCFNDKDYALMSLCSWVNVVGRMTGIDRAAK-------HVVLSTDEIVP---YDHLILCTGQ----QYQVPCPTEADISQHLTNREIWIRNNSITTEGNIIVYGNTIDTYTTVETLLNLGSRIHLV............................................................................................................................................................................................................................................................................................................................... 266
42 -9.770sp|Q9Y2Z2|MTO1_HUMAN Protein MTO1 homolog, mitochondrial OS=Homo sapiens GN=MTO1 PE=1 SV=2  ali   12  39.....VIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICD-PAVWGLRAQIDRKLYKQNMQKEILNTPLL--TVQEGAVEDLILTEPEPEHTG-RVSGVVLVDGSTVYAESVILTTGTFLRGMI----VIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP-SINFSILNKH................................................................................................................................................................................................................................................................................................................................... 256
43 -9.500sp|Q14534|ERG1_HUMAN(removed signalp:1-43) Squalene monooxygenase OS=Homo sapiens GN=SQLE PE=2 SV=3  ali follow..  12  79.NDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDKDLG----LGDTVEGLDAQVVNGYMIHDQESKSEVLSENNQVQSGRAFHHGRFIMSLRKAAMAEPNAK-FIEGVVLQLLEEDDVVMGV---QYKDKETGDIKELHAPLTVVADGLFSKPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVLLLGLTGGGMTVAFKDIKLWRKLLKGIPD............................................................................................................................................................................................................................................................................................................................ 397
44 -9.380sp|O95831|AIFM1_HUMAN Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens GN=AIFM1 PE=1 SV=1  ali   10  130.SHVPFLLIGGGTAAFAAARSIRARDPGARVYMR-PPLSKELWFSDDPNVTKTLRFKQWNGKERSIYFQPPSF--------YVSAQDLPHIENGGVA-------VLTGKKVVQLDVRDN-------MVKLNDGSQIT---YEKCLIATG--GTPRLSAIDRAGAE-VKSRTTLFRKIGDFRSLEKREV......................................................................................................................................................................................................................................................................................................................................................... 300
45 -9.350sp|P50336|PPOX_HUMAN Protoporphyrinogen oxidase OS=Homo sapiens GN=PPOX PE=1 SV=1  ali follow..  14  2..GRTVVVLGGGISGLAASYHLSRAPPKVVLVESSERLGG-WIRSVRGPNG---------------------AIFELGPRGIRPAGALGARTLLLVSELGLDSEV----------------------LPVRGDHPAAQNRF--LYVGGALHALPTGLRGLLRPSPPFSKPLFWAELTKPRGKEPDETVHSFAQRRLGPEVASLAMDAGNSRELSIRS---CFPSLFQAEQTHRSILLGLLLGAGRTPQPDSALIRQALAERWSQW-----------SLRGGLEMLPQALETHLTSRGVSVLRGLSLQAEGRWKVSLRDSSLEADHVISAIPASVLSELLPAEAAP--------LARALSAITAVSVAVVNLVQGFGHLVPSSELGIVYDSVAFPEQD--GSPPGLRVTVMLGGSWLQTLEASGCVLSQELFQQRAQEAAATQLGLK--------EMPSHCLVHLHKNCIP-QYTLGHWQKLESARQFLTAHRLPLT..................................... 445
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;