current user: public
If you have questions about the server, please let us know.

Query: sp|P52209|6PGD_HUMAN 6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens GN=PGD PE=1 SV=3, from H.sapiens

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470    .  480
# Score Template Links and tools%idFirst MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSSYNALast
1 -122.000sp|P52209|6PGD_HUMAN 6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens GN=PGD PE=1 SV=3  ali  100  1MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSSYNA 483
2 -54.900sp|P31937|3HIDH_HUMAN 3-hydroxyisobutyrate dehydrogenase, mitochondrial OS=Homo sapiens GN=HIBADH PE=1 SV=2  ali follow..  15  37ASKTPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDA--------GEQVVSSPADVAEKADRIITMLPTSINAIEAYNGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSGGVGAARSGLTFMVGGVEDEFAAAQELLGCMGSN-------VVYCGAVGTGQAAKICNNMLLAISMIGTAEAMNLGIRLGL----DPKLLAKILNMSSGRCWSSDTYNPVPSANNYQGGFGTTLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMMCAKGYSKKDFSSVFQFLREEET................................................................................................................................................................................ 335
3 -45.200sp|Q49A26|GLYR1_HUMAN Putative oxidoreductase GLYR1 OS=Homo sapiens GN=GLYR1 PE=1 SV=3  ali follow..  15  265PTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQE--------GARLGRTPAEVVSTCDITFACVSDPKAAKDLVSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGLVILAAGDRGLYEDCSSCFQAMGKT-------SFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAHVTGQ----SQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAYI.................................................................................................................................................................................... 552
4 -17.900sp|Q8NFT2|STEA2_HUMAN Metalloreductase STEAP2 OS=Homo sapiens GN=STEAP2 PE=1 SV=3  ali follow..  11  29.RKVTVGVIGSGDFAKSLTIRLIRCGYHVVIGSRNPKFASEFFPHVVD---------VTHHEDALTKTNIIFVAIHREHYTSLWDLR------VGKILIDVSNNAEYLASLFPDSLIVKGFNVVSAWALQLGPKDASRQVYICSNNIQARQQVIELARQLNFIPID-------LGSLSSAREIENLPLRLVAISLATFFFLYSFVRDVIHPYARNQQSDFYKIPIEIVNK-TLPIVAITLLSLVYLAGLLAAAYQKQLGLLSFFFAMVHVAYSLCLPMRRSERYLFLNMAYQQVHANIENSWNEEEVWRIEMYISFGIMSLGLLSLLAVTSIPSVSNALN---------------------WREFSFIQSTLLIYGWKRAFEEEYYRFYTPPNFVLALVLP-------SIVILGKIILFLPCISRKLKRIKK................................................... 463
5 -15.400sp|Q687X5|STEA4_HUMAN Metalloreductase STEAP4 OS=Homo sapiens GN=STEAP4 PE=1 SV=1  ali follow..  12  18.KQETVCIFGTGDFGRSLGLKMLQCGYSVVFGSRNPQKTTLLPSGAE----------VLSYSEAAKKSGIIIIAIHREHYDFLTELT------NGKILVDISNYPESNAEYLAHLVPGKAFNTISAWALQSGALDASRQVFVCGNDSKAKQRVMDIVRNLGLTPMD-------QGSLMAAKEIEKYPLQLFPMWRFPFYLSAVL....................................................................................................................................................................................................................................................................................... 210
6 -13.300sp|Q658P3|STEA3_HUMAN Metalloreductase STEAP3 OS=Homo sapiens GN=STEAP3 PE=1 SV=2  ali follow..  11  27.EAPKVGILGSGDFARSLATRLVGSGFKVVVGSRNPKRTARLFPSAAQ---------VTFQEEAVSSPEVIFVAVFRESSLCSLSDQL-----AGKILVDVSNPTEQEHLQHRESNAEKAFNVISAWTLQAGPRDGNRQVPICGDQPEAKRAVSEMALAMGFMPVD-------MGSLASAWEVE........................................................................................................................................................................................................................................................................................................... 202
7 -12.900sp|O60701|UGDH_HUMAN UDP-glucose 6-dehydrogenase OS=Homo sapiens GN=UGDH PE=1 SV=1  ali follow..  10  2FEIKKICCIGAGYVGGPTCSVIAHMCIRVTVVDVNESRINAWLKEVVESCRGKNLFFSTNIDDAIKEADLVFISVNTPKYIEACARRIVQNSNGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAVLIGGETPEGQRAVQALCAVYEHWVPREKILT---NTWSSELSKLAANAFLAQRISSINSISALCEATGADVEEVATAILVYLCEALNLPEVARYWQQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFESSSIYISKYLMDEGAHLHIYDPKVPREQIVVDLSHPGVSEDDQVSRLVTISKDPYEACDGAHAVVICTEWDM----ELDYERIHKKMLKPAFI................................................................................................................... 438
8 -11.600sp|Q53H96|P5CR3_HUMAN Pyrroline-5-carboxylate reductase 3 OS=Homo sapiens GN=PYCRL PE=1 SV=2  ali follow..  13  6PSPRRVGFVGAGRMAGAIAQGLIRAGKHILASAPTDRNLCHFQA--------LGCRTTHSNQEVLQSCLLVIFATK-PHVLPAVLAEVAPVVTTEHILVSVAAGVSLSTLEELLPPNTRVLRVLPCVVQEGAIVMARGRHV----GSSETNLLQHLLEACGRCEEVPEAYVDIHGLSGSG------------AFVCAFSEALAEGAVKMGMPSSLAHRIAAQTLLG---------TAKMLLHEGQHPAQLRSDVCTPGGTTIYGLHALEQGGLRAATMSAVEAAT...................................................................................................................................................................................................... 265
9 -10.800sp|Q9UDR5|AASS_HUMAN Alpha-aminoadipic semialdehyde synthase, mitochondrial OS=Homo sapiens GN=AASS PE=1 SV=1  ali   5  29.TRRKVLVLGSGYISEPVLEYLSRDGIEITVGSDMKNQIEQLGKKNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPL-----AKACITNKVNMVTASYIT-PALKELEKSVEDAGITIIELGLDPGLD------HMLAMETIDKAKEVGATIESYIS................................................................................................................................................................................................................................................................................................................................. 181
10 -9.640sp|Q16836|HCDH_HUMAN Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens GN=HADH PE=1 SV=3  ali follow..  9  25IIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAK-AGDEFVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDGLHFFN------PVPVMKLVEVIKT-SQKTFESLVDFSKALGKHPVSCKDT--------PGFIVNRLLVPYLMEAIRLYERGDA........................................................................................................................................................................................................................................................................................ 239
11 -9.500sp|P22314|UBA1_HUMAN Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens GN=UBA1 PE=1 SV=3  ali   13  70LQTSSVLVSGLRGLGVEIAKNIILGGVAVTLHDQGTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVE------DFLSGFQVVVL-TNTPLEDQLRVGEFCHNRGIKLVVADTRG................................................................................................................................................................................................................................................................................................................................................................. 193
12 -9.390sp|P41226|UBA7_HUMAN Ubiquitin-like modifier-activating enzyme 7 OS=Homo sapiens GN=UBA7 PE=1 SV=2  ali   12  30IQGARVLVSGLQGLGAEVAKNLVLMGVSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITE------DLLLDFQVVVL-TAAKLEEQLKVGTLCHKHGVCFLAADTRG................................................................................................................................................................................................................................................................................................................................................................. 153
13 -9.360sp|Q9UBT2|SAE2_HUMAN SUMO-activating enzyme subunit 2 OS=Homo sapiens GN=UBA2 PE=1 SV=2  ali   12  15VAGGRVLVVGAGGIGCELLKNLVLTGFHIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMN--DYNVEFFRQFILVMN-ALDNRAARNHVNRMCLAADVPL----IESGTAGYLGQVTTIKKGVTECYECHPK........................................................................................................................................................................................................................................................................................................................................ 164
14 -9.230sp|Q6NXP6|CN148_HUMAN Pyrroline-5-carboxylate reductase-like protein C14orf148 OS=Homo sapiens GN=C14orf148 PE=2 SV=2  ali follow..  12  74PEEFKVGIIGGGHLGKQLAGTLLQLGPSLRISTRRPETLGELQK--------LGIKCFYHNADLVSWADVIFLCCL-PSQLPNICVEIYTSLEKASIVYSFVAA---PLPRLKLLLNHTNI.......................................................................................................................................................................................................................................................................................................................................................................... 187
15 -9.170sp|P41226|UBA7_HUMAN Ubiquitin-like modifier-activating enzyme 7 OS=Homo sapiens GN=UBA7 PE=1 SV=2  ali   9  130LRRQHYLLVGAGAIGCELLKVFALVGLGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYNFFSRVDGVAA-ALDSFQARRYVAARCTHYLKPL----LEAGTSGTWGSATVFMPHVTEAYRAPAS........................................................................................................................................................................................................................................................................................................................................ 287
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 1   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Robinson-Rechavi M, Godzik A. Structural Genomics of Thermotoga maritima Proteins Shows that Contact Order Is a Major Determinant of Protein Thermostability. Structure (Camb). 2005 Jun;13(6):857-60.