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Query: sp|Q02338|BDH_HUMAN D-beta-hydroxybutyrate dehydrogenase, mitochondrial OS=Homo sapiens GN=BDH1 PE=1 SV=3, from H.sapiens

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLATRLSRPLSRLPGKTLSACDRENGARRPLLLGSTSFIPIGRRTYASAAEPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISDMIYIRLast
1 -97.300sp|Q02338|BDH_HUMAN D-beta-hydroxybutyrate dehydrogenase, mitochondrial OS=Homo sapiens GN=BDH1 PE=1 SV=3  ali  100  1MLATRLSRPLSRLPGKTLSACDRENGARRPLLLGSTSFIPIGRRTYASAAEPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISDMIYIR 343
2 -84.900sp|P37059|DHB2_HUMAN(removed signalp:1-20) Estradiol 17-beta-dehydrogenase 2 OS=Homo sapiens GN=HSD17B2 PE=1 SV=1  ali follow..  32  18..........MVCLAGLCAVCLLILSPFWGLILFSVSCFLMYTYLSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNEN--GPGAEELRRTCSPRLSVLQMDITKPVQIKDAYSKVAAMLQ--DRGLWAVINNAGVGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNIAGTS-DKWEKLEKDILDHLPAEVQEDYGQDYILAQRNFLLLINSLASKDFSPVLRDIQHAILAKSPFAYYTP-GKGAYLWICLAHYLPIGIYDYFAKR 345
3 -84.200sp|O14756|H17B6_HUMAN 17-beta-hydroxysteroid dehydrogenase type 6 OS=Homo sapiens GN=HSD17B6 PE=1 SV=1  ali follow..  37  1..........................MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKG----AEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVG--DRGLWGLVNNAGILTITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVA-FFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGYFRTGMT--NMTQSLERMKQSWKEAPKHIKETYGQQYFDALYNIMKEGLLNCSTNLNLVTDCMEHALTSVHPRTRYSA-GWDAKFFFIPLSYLPTSLADYILTR 308
4 -84.200sp|Q9BPW9|DHRS9_HUMAN(removed signalp:1-17) Dehydrogenase/reductase SDR family member 9 OS=Homo sapiens GN=DHRS9 PE=1 SV=1  ali follow..  35  1...........................................RKGKLKIEDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESG----STALKAETSERLRTVLLDVTDPENVKRTAQWVKNQVG--EKGLWGLINNAGVGVLAPTDWLTLEDYREPIEVNLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLRRDMKAFGVHVSCIEPGLFKTNLA--DPVKVIEKKLAIWEQLSPDIKQQYGEGYIEKSLDKLKGNKSYVNMDLSPVVECMDHALTSLFPKTHYAA-GKDAKIFWIPLSHMPAALQDFLLLK 291
5 -84.100sp|Q8NEX9|DR9C7_HUMAN Short-chain dehydrogenase/reductase family 9C member 7 OS=Homo sapiens GN=SDR9C7 PE=2 SV=1  ali follow..  35  1..............................MAALTDLSFMYRWFKNCNLVGNLSEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEG----SQKLQRDTSYRLQTTLLDVTKSESIKAAAQWVRDKVG--EQGLWALVNNAGVGLSGPNEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIG-GGYCVSKFGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAIL--GKENLESRMRKLWERLPQETRDSYGEDYFRIYTDKLKNIMQVAEPRVRDVINSMEHAIVSRSPRIRYNP-GLDAKLLYIPLAKLPTPVTDFILSR 304
6 -83.500sp|O75452|RDH16_HUMAN(removed signalp:1-25) Retinol dehydrogenase 16 OS=Homo sapiens GN=RDH16 PE=1 SV=2  ali follow..  39  1...................................................HLRDKYVFITGCDSGFGKLLARQLDARGLRVLAACLTEKG----AEQLRGQTSDRLETVTLDVTKTESVAAAAQWVKECVR--DKGLWGLVNNAGISLTAPNELLTKQDFVTILDVNLLGVIDVTLSLLPLVRRARGRVVNVSSVMGRVS-LFGGGYCISKYGVEAFSDSLRRELSYFGVKVAMIEPGYFKTAVT--SKERFLKSFLEIWDRSSPEVKEAYGEKFVADYKKSAEQMEQKCTQDLSLVTNCMEHALIACHPRTRYSA-GWDAKLLYLPMSYMPTFLVDAIMYW 283
7 -83.000sp|P80365|DHI2_HUMAN(removed signalp:1-21) Corticosteroid 11-beta-dehydrogenase isozyme 2 OS=Homo sapiens GN=HSD11B2 PE=1 SV=2  ali follow..  30  17..........LALLAALDWLCQRLLPPPAALAVLAAAGWIALSRLARPQRLPVATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPG--AIELRTCCSPRLRLLQMDLTKPGDISRVLEFTKAHTT--STGLWGLVNNAGHEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESV-RNVGQWEKRKQLLLANLPQELLQAYGKDYIEHLHGQFLHSLRLAMSDLTPVVDAITDALLAARPRRRYYP-GQGLGLMYFIHYYLPEGLRRRFLQA 344
8 -82.600sp|Q92781|RDH1_HUMAN(removed signalp:1-23) 11-cis retinol dehydrogenase OS=Homo sapiens GN=RDH5 PE=1 SV=1  ali follow..  35  1..................................................LPASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSG----AEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVK--EAGLFGLVNNAGVGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANG-GGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVT--NLESLEKTLQACWARLPPATQAHYGGAFLTKYLKMQQRIMNLCDPDLTKVSRCLEHALTARHPRTRYSP-GWDAKLLWLPASYLPASLVDAVLTW 285
9 -64.900sp|P14061|DHB1_HUMAN Estradiol 17-beta-dehydrogenase 1 OS=Homo sapiens GN=HSD17B1 PE=1 SV=3  ali follow..  26  1....................................................MARTVVLITGCSSGIGLHLAVRLASQSFKVYATLRDLKTQGRLWEAARALAPGSLETLQLDVRDSKSVAAARERVTE------GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQ---------YLAHSKQVFREAAQNPEEVAEVFLTALRAPKPTLRYFTT---ERFLPLLRMRLDDPSGSNYVTA 279
10 -63.700sp|Q9NYR8|RDH8_HUMAN Retinol dehydrogenase 8 OS=Homo sapiens GN=RDH8 PE=1 SV=1  ali follow..  24  1..................................................MAAAPRTVLISGCSSGIGLELAVQLAKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDVCSDESVAQCLSCIQ-------GEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRRGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFISLVEPGPVVTEFEGKLLAQVSMAEF-------PGTDPETLHYFRDLYLPASRKLFCSVGQNPQDVVQAIVNVISSTRPPLRRQTNIRYSPLTTLKTVDSSGSLYVRTTHR 283
11 -55.100sp|A6NNS2|DRS7C_HUMAN(removed signalp:1-18) Dehydrogenase/reductase SDR family member 7C OS=Homo sapiens GN=DHRS7C PE=2 SV=3  ali follow..  20  1....................................LLFIYQEVSRLWSKSAVQNKVVVITDAISGLGKECARVFHTGGARLVLCGKNWERLENLYDALISVADPTPKLVLLDLSDISCVPDVAKEVLDCYG----CVDILINNASVKVKGPAHKISLELDKKIMDANYFGPITLTKALLPMISRRTGQIVLVNNIQGKFGIPFRTTYAASKHAALGFFDCLRAEVEEYDVVISTVSPTFIRSYHVYPEQGNWEASIWKFFFRKLTY------------------------GVHPVEVAEEVMRTV--RRKKQEVFMANPIPKAAVYVRTFFPE-FFFAVVAC 282
12 -54.000sp|P28845|DHI1_HUMAN(removed signalp:1-23) Corticosteroid 11-beta-dehydrogenase isozyme 1 OS=Homo sapiens GN=HSD11B1 PE=1 SV=3  ali follow..  19  1............................................NEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMG----GLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSRVNVSITLCVLGLIDTET----------------------------------AMKAVSGIVHMQAAPKEECALEIIKGGALRQ---EEVYYDSSLWTTLLIRNPCRK-ILEFLYST 259
13 -52.700sp|Q6IAN0|DRS7B_HUMAN Dehydrogenase/reductase SDR family member 7B OS=Homo sapiens GN=DHRS7B PE=1 SV=2  ali follow..  24  24..........................ILPLLFGCLGVFGLFRLLQWVRGKAYLRNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHTHKPYLVTFDLTDSGAIVAAAAEILQCFG----YVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSRYGVM-------------------------DTTTAQGRSPVEVAQDVLAAV--GKKKKDVILADLLPSLAVYLRTLAPG-LFFSLMAS 314
14 -52.500sp|Q9Y394|DHRS7_HUMAN(removed signalp:1-28) Dehydrogenase/reductase SDR family member 7 OS=Homo sapiens GN=DHRS7 PE=1 SV=1  ali follow..  21  4....................................LTLLWAEWQGRRPEWELTDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNKDILVLPLDLTDTGSHEAATKAVLQEFG----RIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYGIIVSNICPGPVQSNIVENSLAGEVTKTIG-------------------------NNGDQSHKMTTSRCVRLMLISM--ANDLKEVWISEQPFLLVTYLWQYMPT-WAWWITNK 283
15 -48.900sp|Q7Z5J1|DHI1L_HUMAN(removed signalp:1-15) Hydroxysteroid 11-beta-dehydrogenase 1-like protein OS=Homo sapiens GN=HSD11B1L PE=2 SV=1  ali follow..  22  2..........................................YWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLG----GLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVAITMCVLGLRDRASAAEAVRSSTSRPRQ.................................................................................... 216
16 -48.500sp|Q8N3Y7|RDHE2_HUMAN(removed signalp:1-25) Epidermal retinol dehydrogenase 2 OS=Homo sapiens GN=SDR16C5 PE=2 SV=2  ali follow..  21  1........................................MIFALLPKPRKNVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGD----VSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQGIKTTIVCPFFIKTGMFEGCTTGCPSLLPIL---------------------------------EPKYAVEKIVEAILQEK---MYLYMPKLLYFMMFLKSFLPLKTGLLI... 264
17 -48.300sp|Q8NBQ5|DHB11_HUMAN(removed signalp:1-19) Estradiol 17-beta-dehydrogenase 11 OS=Homo sapiens GN=HSD17B11 PE=1 SV=3  ali follow..  19  3........................................FVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGL-GAKVHTFVVDCSNREDIYSSAKKVKAEIGD----VSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALGVKTTCLCPNFVNTGFIKNPSTSLGPTL------------------------------------EPEEVVNRLMHGILTEQ---KMIFIPSSIAFLTTLERILPERFLAVL... 262
18 -47.900sp|Q7Z5P4|DHB13_HUMAN(removed signalp:1-19) 17-beta-hydroxysteroid dehydrogenase 13 OS=Homo sapiens GN=HSD17B13 PE=2 SV=1  ali follow..  20  3........................................LVKFFIPQRRKSVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKL-GVTAHAYVVDCSNREEIYRSLNQVKKEVGD----VTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGIKTSCLCPVFVNTGFTKNPSTRLWPVL------------------------------------ETDEVVRSLIDGILTNK---KMIFVPSYINIFLRLQKFLPERASAIL... 262
19 -47.700sp|Q06136|KDSR_HUMAN(removed signalp:1-25) 3-ketodihydrosphingosine reductase OS=Homo sapiens GN=KDSR PE=1 SV=1  ali follow..  18  1................................................KPLALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSKQVVLCISVDVSQDNQVENVIKQAQEKLG----PVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYPPDTDTPGFAEENRTKPLETRLISETTS--------------------------VCKPEQVAKQIVKDAIQGN---FNSSLGSDGYMLSALTCGMA.......... 257
20 -47.300sp|O75911|DHRS3_HUMAN(removed signalp:1-23) Short-chain dehydrogenase/reductase 3 OS=Homo sapiens GN=DHRS3 PE=1 SV=2  ali follow..  20  7..............................................PAKLRDLSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGD----ITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLD-GVSATTVLPFHTSTEMFQGMRVRFPNLFPPL---------------------------------KPETVARRTVEAVQLNQALL---LLPWTMHALVILKSILPQAALEEI... 262
21 -46.700sp|Q8IZV5|RDH10_HUMAN(removed signalp:1-23) Retinol dehydrogenase 10 OS=Homo sapiens GN=RDH10 PE=1 SV=1  ali follow..  19  1..........................................RWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDQVFTYTCDVGKRENVYLTAERVRKEVGE----VSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKA-GIKTTLVCPYLVDTGM-------------------------------FRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQ---PMICTPRLMYIVTFMKSILPFEAVVCM... 288
22 -45.800sp|Q6UWP2|DHR11_HUMAN Dehydrogenase/reductase SDR family member 11 OS=Homo sapiens GN=DHRS11 PE=1 SV=1  ali follow..  20  1............................................MARPGMERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGPGTLIPYRCDLSNEEDILSMFSAIRSQHS----GVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNGHIININSMSGHRVLPLSVFYSATKYAVTALTEGLRQELRQTHIRATCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAEAVI.................................................................. 237
23 -44.100sp|Q6PKH6|DR4L2_HUMAN(removed signalp:1-20) Dehydrogenase/reductase SDR family member 4-like 2 OS=Homo sapiens GN=DHRS4L2 PE=2 SV=1  ali follow..  23  1.............................................RMTRRDPLTNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGE-GLSVTGTVCHVGKAEDRERLVAMAVKLHG----GIDILVSNAAVNFFGSLMDVTEEVWDKTLDINVKAPALMTKAVVPEMKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVNCLHLDLSRLAS.................................................................................................. 197
24 -41.900sp|Q9NUI1|DECR2_HUMAN Peroxisomal 2,4-dienoyl-CoA reductase OS=Homo sapiens GN=DECR2 PE=1 SV=1  ali follow..  20  26....................................................LRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFG----RIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASP.............................................................................. 235
25 -41.800sp|Q53GQ0|DHB12_HUMAN(removed signalp:1-29) Estradiol 17-beta-dehydrogenase 12 OS=Homo sapiens GN=HSD17B12 PE=1 SV=2  ali follow..  22  1..................................LFTALRVWGVGNEAGVGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLA------GLEIGILVNNVGMSYEYPEYFLDVPDIKKMININILSVCKMTQLVLPMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTL-------------------------------------DKPSPETFVKSAIKTV-----LQSRTNGYLIHALMGSIISNLPSWIYLKIVMN 267
26 -41.400sp|P37058|DHB3_HUMAN(removed signalp:1-24) Testosterone 17-beta-dehydrogenase 3 OS=Homo sapiens GN=HSD17B3 PE=1 SV=2  ali follow..  18  24......................................................GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKLA------GLEIGILVNNVGMLLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLNTNV-------------------------------------ITKTADEFVKESLNYV-----IGGETCGCLAHEILAGFLSLIPAWAFYSGAFQ 268
27 -40.900sp|Q9BPX1|DHB14_HUMAN 17-beta-hydroxysteroid dehydrogenase 14 OS=Homo sapiens GN=HSD17B14 PE=1 SV=1  ali follow..  26  6...................................................RYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQEL-----PGAVFILCDVTQEDDVKTLVSETIRRFG----RLDCVVNNAGHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQ..................................................................... 220
28 -40.800sp|Q13268|DHRS2_HUMAN Dehydrogenase/reductase SDR family member 2 OS=Homo sapiens GN=DHRS2 PE=1 SV=3  ali follow..  21  7...............................................DRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGE-GLSVAGIVCHVGKAEDREQLVAKALEHCG----GVDFLVCSAGVNLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDF.................................................................................................. 200
29 -40.700sp|Q3SXM5|HSDL1_HUMAN Inactive hydroxysteroid dehydrogenase-like protein 1 OS=Homo sapiens GN=HSDL1 PE=1 SV=3  ali follow..  16  14.IARSCNCYMEALALVGAWYTARKSITVICDFYSLIRLHFIPRLGSRADLIKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-----VGILVNNVGVFYPQYFTQLSEDKLWDIINVNIAAASLMVHVVLPMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTAPS---------------------------------NFLHRCSWLVPSPKVYAHHAVSTL-----ISKRTTGYWSHSIQFLFAQYMPEWLWVWGANI 316
30 -40.500sp|P35270|SPRE_HUMAN Sepiapterin reductase OS=Homo sapiens GN=SPR PE=1 SV=1  ali follow..  21  4...................................................GLGRAVCLLTGASRGFGRTLAPLLASLGSVLVLSARNDEALRQLEAELGAERSGRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEP--NVRVLNYAPGPLDTDMQQLARE----------TSVDPDMRKGLQELKAKGKL-----------VDCKVSAQKLLSLLEKDE................................. 249
31 -40.000sp|Q92506|DHB8_HUMAN Estradiol 17-beta-dehydrogenase 8 OS=Homo sapiens GN=HSD17B8 PE=1 SV=2  ali follow..  22  1............................................MASQLQNRLRSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGRGNHAAFQADVSEARAARCLLEQVQACFSR----PSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDKITE.................................................................................... 220
32 -40.000sp|Q8N4T8|CBR4_HUMAN Carbonyl reductase family member 4 OS=Homo sapiens GN=CBR4 PE=1 SV=3  ali follow..  25  2......................................................DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL----GGDHLAFSCDVAKEHDVQNTFEELEKHLGR----VNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDM.................................................................................................. 185
33 -39.900sp|Q7Z4W1|DCXR_HUMAN L-xylulose reductase OS=Homo sapiens GN=DCXR PE=1 SV=2  ali follow..  24  4...................................................FLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRE-----CPGIEPVCVDLGDWEATERALGSV--------GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLRGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM.................................................................................................. 186
34 -39.700sp|P16152|CBR1_HUMAN Carbonyl reductase [NADPH] 1 OS=Homo sapiens GN=CBR1 PE=1 SV=3  ali follow..  22  1..................................................MSSGIHVALVTGGNKGIGLAIVRDLCRLSGDVVLTARDVTRGQAAVQQLQAE-GLSPRFHQLDIDDLQSIRALRDFLRKEYG----GLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQ-GRVVNVSSIMSVRAL--SSAYGVTKIGVTVLSRIHARKLSE-KILLNACCPGWVRTDMAGPKATKSPEEGAETLALLPPDAEGPHGQFVSE................................................................. 271
35 -39.300sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member 4 OS=Homo sapiens GN=DHRS4 PE=1 SV=3  ali follow..  24  25...............................................TRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGE-GLSVTGTVCHVGKAEDRERLVATAVKLHG----GIDILVSNAAVNFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSF.................................................................................................. 219
36 -39.300sp|O75828|CBR3_HUMAN Carbonyl reductase [NADPH] 3 OS=Homo sapiens GN=CBR3 PE=1 SV=3  ali follow..  22  1..................................................MSSCSRVALVTGANRGIGLAIARELCRQSGDVVLTARDVARGQAAVQQLQAE-GLSPRFHQLDIDDLQSIRALRDFLRKEYG----GLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPH-GRVVNISSLQCLRAF--NSPYGVSKLGVTVLSRILARRLDE-RILVNACCPGPVKTDMDGKDSIRTVEEGAETLALLPPDATEPQGQLVHD................................................................. 271
37 -38.900sp|Q16698|DECR_HUMAN 2,4-dienoyl-CoA reductase, mitochondrial OS=Homo sapiens GN=DECR1 PE=1 SV=1  ali follow..  19  56...................................................SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKVAG----HPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFVTLEIGKQLIKAQAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIP.............................................................................. 267
38 -38.500sp|P0CG22|DR4L1_HUMAN Putative dehydrogenase/reductase SDR family member 4-like 2 OS=Homo sapiens GN=DHRS4L1 PE=5 SV=1  ali follow..  20  29...................................................PLTNKVALVTASTDWIGFAVAQRLAQDGAHVVVSRRKQQNVDQAVATLQGE-GLSMTGTVCHVGKMKDWERLVATAMKLHG----VIDILSLSITNSFWFTLLQTAEEAWDRNLDINGKALALMIKAVVPEMKRGGGSVGFLASVAAFRPLPGFSPYNVSKTALLGLNKTLAIELAPRNIRVNCLAPGLIKTSF.................................................................................................. 222
39 -38.300sp|Q9BY49|PECR_HUMAN Peroxisomal trans-2-enoyl-CoA reductase OS=Homo sapiens GN=PECR PE=1 SV=2  ali follow..  20  16....................................................LQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQATKQARVIPIQCNIRNEEEVNNLVKSTLDTFG----KINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSWMKEHGGSIVNIIVP-TKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFITGQSVDV............................................. 261
40 -38.300sp|P15428|PGDH_HUMAN 15-hydroxyprostaglandin dehydrogenase [NAD+] OS=Homo sapiens GN=HPGD PE=1 SV=1  ali follow..  21  1..................................................MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQEPQKTLFIQCDVADQQQLRDTFRKVVDHFG----RLDILVNNAGV--------NNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAANLMNSGVRLNAICPGFVNTAI------------------LESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDD.................................. 236
41 -37.900sp|Q9BUT1|BDH2_HUMAN 3-hydroxybutyrate dehydrogenase type 2 OS=Homo sapiens GN=BDH2 PE=1 SV=2  ali follow..  21  1.................................................MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK------YPGIQTRVLDVTKKKQIDQFANEV--------ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPMLAQKSGNIINMSSVASSVGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPS.................................................................................................. 184
42 -37.100sp|Q96LJ7|DHRS1_HUMAN Dehydrogenase/reductase SDR family member 1 OS=Homo sapiens GN=DHRS1 PE=1 SV=1  ali follow..  17  4...................................................PMNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCV-PVVCDSSQESEVRSLFEQVDR---EQQGRLDVLVNNAYAGV-KAFWETPASMWDDINNVGLRGHYFCSVYGARMVPAGQGLIVVISSPGS-LQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMAKEEVLQDPVLKQFKSAFSSAETTELSGKCVVALATDPNILSLSGKVLP............................................ 254
43 -34.900sp|Q8NBN7|RDH13_HUMAN(removed signalp:1-17) Retinol dehydrogenase 13 OS=Homo sapiens GN=RDH13 PE=1 SV=2  ali follow..  20  14...............................................PSKATIPGKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETNHHVNARHLDLASLKSIREFAAKIIEE----EERVDILINNAGVMRC---HWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASASRIINLSSLAHVAGYNTKAAYCQSKLAIVLFTKELSRRLQGSGVTVNALHPGVARTEL.................................................................................................. 220
44 -34.700sp|Q8TC12|RDH11_HUMAN(removed signalp:1-20) Retinol dehydrogenase 11 OS=Homo sapiens GN=RDH11 PE=1 SV=2  ali follow..  22  18...................................................QLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTNQQVLVRKLDLSDTKSIRAFAKGFLAE----EKHLHVLINNAGVMMC---YSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESASRIVNVSSLAHHLGYNAGLAYCHSKLANILFTQELARRLKGSGVTTYSVHPGTVQSELVRHSKTPQQGAQTSLHCALTEGLEILSGNHFSD................................................................. 266
45 -34.700sp|Q96NR8|RDH12_HUMAN(removed signalp:1-20) Retinol dehydrogenase 12 OS=Homo sapiens GN=RDH12 PE=1 SV=3  ali follow..  22  12...............................................RTNVQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTNSQVLVRKLDLSDTKSIRAFAEGFLAE----EKQLHILINNAGVMMC---YSKTADGFETHLGVNHLGHFLLTYLLLERLKVSAARVVNVSSVAHHIGYSRGFAYCHSKLANVLFTRELAKRLQGTGVTTYAVHPGVVRSELVRHSKTAREGAQTSLHCALAEGLEPLSGKYFSD................................................................. 264
46 -34.000sp|Q9HBH5|RDH14_HUMAN(removed signalp:1-20) Retinol dehydrogenase 14 OS=Homo sapiens GN=RDH14 PE=1 SV=1  ali follow..  23  20...................................................LMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRSGVGELIVRELDLASLRSVRAFCQEMLQE----EPRLDVLINNAGIFQC---YMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSASRIVVVSSKLYKYGYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNL.................................................................................................. 234
47 -33.800sp|A0PJE2|DHR12_HUMAN Dehydrogenase/reductase SDR family member 12 OS=Homo sapiens GN=DHRS12 PE=2 SV=2  ali follow..  15  36..................................................VQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIRESGNQNIFLHIVDLSDPKQIWKFVENFKQ-----EHKLHVLINNAGCMVN---RELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHPRVITVSSGGERTPFDGTMVYAQNKRQQVVLTERWAQGHP--AIHFSSMHPGWADTPGVRQAMPGFHARFGMLWLALSSAAAAQPSGRFFQDRKPVSTHLPLATASSSPAEEEKLIEILEQLAQTFK............................. 317
48 -33.400sp|P51659|DHB4_HUMAN Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens GN=HSD17B4 PE=1 SV=3  ali   24  5..................................................LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVGVGKGSLAADKVVEEIRRRGGKAV----ANYDSVEEGEKVVKTALDAFG----RIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAPNAGSRMTQTVMPEDLVEALK..................................................................................... 214
49 -33.200sp|P09417|DHPR_HUMAN Dihydropteridine reductase OS=Homo sapiens GN=QDPR PE=1 SV=2  ali follow..  12  2..............................................AAAAAAGEARRVLVYGGRGALGSRCVQAFRARNWWVASVDVVENEEASASIIVK---------MTDSFTEQADQVTAEVGKLLGEE----KVDAILCVAGGWAGGNKSKSLFKNCDLMWKQSIWTSTISSHLATKHLKEG-GLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSPPGAAAIAVLPVTLDTPM.................................................................................................. 189
50 -33.200sp|Q6UX07|DHR13_HUMAN(removed signalp:1-25) Dehydrogenase/reductase SDR family member 13 OS=Homo sapiens GN=DHRS13 PE=1 SV=1  ali follow..  21  4...............................................GGMGNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESNNEVIFMALDLASLASVRAFATAFLSS----EPRLDILIHNAGISSCGRTR----EAFNLLLRVNHIGPFLLTHLLLPCLKACASRVVVVASAAHCRGRQELRAYADTKLANVLFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGWGGAQTPLYCALQEGIEPLSGRYFAN................................................................. 259
51 -33.200sp|Q8N5I4|DHRSX_HUMAN(removed signalp:1-31) Dehydrogenase/reductase SDR family member on chromosome X OS=Homo sapiens GN=DHRSX PE=2 SV=2  ali follow..  21  5...............................................PVFPPRPDRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETNDKVEFLYCDLASMTSIRQFVQKFKMK----KIPLHVLINNAGVMMV---QRKTRDGFEEHFGLNYLGHFLLTNLLLDTLKESSARVVTVSSATHYVAYSPHAAYAQSKLALVLFTYHLQRLLAAEGVTANVVDPGVVNTDV.................................................................................................. 216
52 -32.600sp|Q99714|HCD2_HUMAN(removed signalp:1-27) 3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens GN=HSD17B10 PE=1 SV=3  ali follow..  19  1........................................................................ERLVGQGASAVLLDLPNSGGEAQAKKL----GNNCVFAPADVTSEKDVQTALALAKGKFG----RVDVAVNCAGIAVLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLAS.................................................................................... 192
53 -31.900sp|Q6YN16|HSDL2_HUMAN Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens GN=HSDL2 PE=1 SV=1  ali follow..  18  7...................................................RLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEKALPCIVDVRDEQQISAAVEKAIKKFG----GIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRGTYLASKACIPYLKKSKAHILNISPPLNLNPFKQHCAYTIAKYGMSMYVLGMAEEFKG-EIAVNALWPKTAIHTA.................................................................................................. 204
54 -30.200sp|Q9NZC7|WWOX_HUMAN WW domain-containing oxidoreductase OS=Homo sapiens GN=WWOX PE=1 SV=1  ali follow..  21  121...................................................DFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWKAKVEAMTLDLALLRSVQHFAEAFKAK----NVPLHVLVCNAAT--FALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAARVIVVSSESHRFTYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIHRSKSMQQGAATTVYCAAVPELEGLGGMYFNN................................................................. 378
55 -27.700sp|P56937|DHB7_HUMAN(removed signalp:1-19) 3-keto-steroid reductase OS=Homo sapiens GN=HSD17B7 PE=1 SV=1  ali follow..  17  6...........................................................................EDDELHLCLACRNMSKAEAVCAALLASHTAEVTIVQVDVSNLQSVFRASKELKQRFQR----LDCIYLNAGIMPNPQLNIITADGLQEVFETNVFGHFILIRELEPLLCHSDSQLIWTSSRSARKSSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNL.................................................................................................. 211
56 -17.100sp|Q8IZJ6|TDH_HUMAN Inactive L-threonine 3-dehydrogenase, mitochondrial OS=Homo sapiens GN=TDH PE=2 SV=1  ali follow..  11  43..............................................SASFSDTDHPRVLITGALGQLGVGLANLLRKRFGKDSVILSDIRKP-------PDHVFHSGPFIYSDILDYKNLREIVV---------NNRITWLFHYSAL-----LSAFGEANVSLARAVNITGLHNI----LDVAAEHNLQLFVPSTIGAFGPTS-RTIYGVSKVHAELMGETMQ---SRFSMMPQSM........................................................................................................... 216
57 -16.800sp|O60547|GMDS_HUMAN GDP-mannose 4,6 dehydratase OS=Homo sapiens GN=GMDS PE=1 SV=1  ali follow..  13  19..................................................MGKPRNVALITGITGQDGSYLAEFLLEKGYEVHGSSFNTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVKPTE---------IYNLGAQSHVK----ISFDLAEYTADVDGVGTLRLLDAVKTCGLINSVKFYQASTLYGKVPFYPRSPYGAAKLYAYWIVVNFR---EAYNLFAVNGILFNHESPRRGANFVTRKISRSVAKIYLGQLECFSLGN------------DAKRDWGHAKDYVEAMWLMLQNDEPEDFVIATGEVHSVREFVEKSF........... 289
58 -16.400sp|P49327|FAS_HUMAN Fatty acid synthase OS=Homo sapiens GN=FASN PE=1 SV=3  ali   18  83.....................................................AHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGIRTGYQAKQ-RRQGVQVQVSTSNISSLEGARGLIAEAAQL-----GPVGGVFNLAVVLRDGLLENQTPEFFQDVCKPKYSGTLNLDRVTREACPELD--FVVFSSVSCGRGNAGQSNYGFANSAMERICEKRRHE----GLPGLAVQWGAI...................................................................................................... 263
59 -15.400sp|Q16795|NDUA9_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Homo sapiens GN=NDUFA9 PE=1 SV=2  ali follow..  12  49..................................................SSVSGIVATVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMHLRPMGDL--GQLLFLEWDARDKDSIRRVVQ-----------HSNVVINLIGR--------DWETKNFDFEDVFVKIPQAIAQL---SKEAGVEKFIHVSHLNANIKSS--SRYLRNKAVGEKV-------VRDAFPEAIIVKPSDI-------REDRFLNSFASMHRFGPIPLGSLGWKTVKQPVY-------------VVDVSKGIVNAVKDPDANGKFAFVGPSRYLLFHLVKYI........... 280
60 -14.900sp|Q9H2F3|3BHS7_HUMAN 3 beta-hydroxysteroid dehydrogenase type 7 OS=Homo sapiens GN=HSD3B7 PE=1 SV=2  ali follow..  15  2...............................................ADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEE-LKTGPVRVTAIQGDVTQAHEVAAAVA-----------GAHVVIHTAGL-----VDVFGRASPKTIHEVNVQGTRNVIEA---CVQTGTRFLVYTSSME--YEAVHRHPYPCSKALAEVLEANGRKVRGGLPLVTCALRPTGISVEHGRVYVGNVAWMHVLAARELEQRATLMGGQVYFCYDGSPYRSY--------EDFNMEFLGPCGLRLVGARPLLPYWLLVFLAALNALL........... 305
61 -14.300sp|A6NKP2|D42E2_HUMAN Putative short-chain dehydrogenase/reductase family 42E member 2 OS=Homo sapiens GN=SDR42E2 PE=3 SV=3  ali follow..  15  25..............................................QAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRP---------QWELSPETKFIQADVRDEEALYRAFE-----------GVDCVFHVASYGMSGA----EKLQKEQIESINVGGTKLVIDVCV---RRRVPRLIYTSTVN---LDEHVDHYSRTKAIADTLMANGMPLPGGGTLRTCVLRPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGES................................ 282
62 -14.200sp|P14060|3BHS1_HUMAN 3 beta-hydroxysteroid dehydrogenase/Delta 5-  ali follow..  13  1....................................................MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELEEFSKLQNKTKLTVLEGDILDEPFLKRACQ-----------DVSVIIHTACI-----IDVFGVTHRESIMNVNVKGTQLLLEA---CVQASVPVFIYTSSIE--LENTWPAPYPHSKKLAEVLAANGWNLKNGGTLYTCALRPGEGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALQDPKKAP................................................. 247
63 -14.200sp|Q15738|NSDHL_HUMAN Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating OS=Homo sapiens GN=NSDHL PE=1 SV=2  ali follow..  14  30...............................................EKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQ-----------QGFDNPQVRFFLGDLCSRQDLYPALK-----------GVNTVFHCASPPPSS-------NNKELFYRVNYIGTKNVIETCK---EAGVQKLILTSSAS--YAMKPIDYYTETKILQERA--VLGANDPEKNFLTTAIRPHGI...................................................................................................... 203
64 -14.000sp|Q8WUS8|D42E1_HUMAN Short-chain dehydrogenase/reductase family 42E member 1 OS=Homo sapiens GN=SDR42E1 PE=2 SV=2  ali follow..  15  5...................................................RSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSP---------AQTIPEGIKFIQGDIRHLSDVEKAFQDAD---------VTCVFHIASYGMS----GREQLNRNLIKEVNVRGTDNILQVCQ---RRRVPRLVYTSTFN---LHLHPDHYSRTKSIAEQKANATPLDRGDGVLRTCALRPGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKGHIASGQPYFISDGRP................................ 259
65 -13.600sp|P26439|3BHS2_HUMAN 3 beta-hydroxysteroid dehydrogenase/Delta 5-  ali follow..  13  2......................................................GWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKQNRTKLTVLEGDILDEPFLKRACQ-----------DVSVVIHTACI-----IDVFGVTHRESIMNVNVKGTQLLLEA---CVQASVPVFIYTSSIE--LENTWPTPYPYSKKLAEVLAANGWNLKNGDTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAAHILALRALRDPKKAPSVRGQFYYISDDTPHQSY............................ 264
66 -13.200sp|P30043|BLVRB_HUMAN Flavin reductase OS=Homo sapiens GN=BLVRB PE=1 SV=3  ali follow..  14  1....................................................MAVKKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSS-------RLPSEGPRPAHVVVGDVLQAADVDKTVA-----------GQDAVIVLLGTRNDLSPTTVMSEGARNIVAA--------------MKAHGVDKVVACTSAFLLWDPTKVPPRLQAVTDDHIRMHKV---LRESGLKYVAVMPPHIGDQ................................................................................................... 157
67 -12.500sp|O95455|TGDS_HUMAN dTDP-D-glucose 4,6-dehydratase OS=Homo sapiens GN=TGDS PE=1 SV=1  ali follow..  16  12.................................................LPGGFAKRVLVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYCASLKNLETSNKQNYKFIQGDICDSHFVKLLFE---------TEKIDIVLHFAAQTHVDL----SFVRAFEFTYVNVYGTHVLVSAAH---EARVEKFIYVSTVYGGSPKQPTNPYASSKAAAECFVQSYW---EQYKFPVVITRPHQYPEKVIPKFISLLQHNRKCCIHGSGLQTRN------------------------ATDVVEAFLTVLKKGKPGEIYNIGTNFEMSVVQLAKEL........... 272
68 -11.900sp|Q14376|GALE_HUMAN UDP-glucose 4-epimerase OS=Homo sapiens GN=GALE PE=1 SV=2  ali follow..  14  2......................................................AEKVLVTGGAGYIGSHTVLELLEAGYLPVVAFRGGGSLPESLRRVQELTGRSVEFEEMDILDQGALQRLFK---------KYSFMAVIHFAGLKAVGE----SVQKPLDYYRVNLTGTIQLLEI---MKAHGVKNLVFSSSATAHPTGGCTNPYGKSKFFIEEMIRDLCQ--ADKTWNAVLLR---YFNPTGAHASGCIGEDPQGIPNNLMPYVSQVFGNDYDTEDGTGVRDYI-----HVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMV........... 281
69 -11.600sp|Q9NZL9|MAT2B_HUMAN Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens GN=MAT2B PE=1 SV=1  ali follow..  14  21...............................................EEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPK---------------FEQVNLLDSNAVHHIIHDFQPHV---------IVHCAAERRPDVVE----NQPDAASQLNVDASGNLAKE----AAAVGAFLIYISSFDGTIPAP-LNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEK......................................................... 237
70 -10.700sp|Q8NBZ7|UXS1_HUMAN(removed signalp:1-35) UDP-glucuronic acid decarboxylase 1 OS=Homo sapiens GN=UXS1 PE=1 SV=1  ali follow..  14  48.................................................LSEKDRKRILITGGAGFVGSHLTDKLMMDGHEVTV-------VDNFFTGRKRNVEHWIGHENFELINHDVVEPLYI-----------EVDQIYHLASPASPPNYMYNPIKT----LKTNTIGTLNM----LGLAKRVGARLLLASTVYGD-PIGPRACYDEGKRVAETMCYAYMKQ---EGVEVRVAR-NTFGPRMHMNDGRVVSNFILQALQGEPLTVYGSYVSDLVNGLVALMNNLGNPEEHTILEFAQLIKNLVGSG.................................. 310
71 -9.910sp|Q9HBL8|NMRL1_HUMAN NmrA-like family domain-containing protein 1 OS=Homo sapiens GN=NMRAL1 PE=1 SV=1  ali follow..  18  2....................................................VDKKLVVVFGGTGAQGGSVARTLLEDGFKVRVVTRNPRK-----KAAKELRLQGAEVVQGDQDDQVIMELALN-----------GAYATFIVTNYWESCSQEQEVKQGKLLADLARRLGLHYVVYSGLENIKKLTAGRLAA-------------AHFDGKGEVEEY-------FRDIGVPMTSVRLPCYFENL.................................................................................................. 159
72 -9.560sp|Q9BUP3|HTAI2_HUMAN Oxidoreductase HTATIP2 OS=Homo sapiens GN=HTATIP2 PE=1 SV=2  ali follow..  11  15...................................................RMQNKSVFILGASGETGRVLLKEILEQGLFSKVTLIGRRKLTFDEEAYKN-----VNQEVVDFEKLDDYASAFQGHDVGF------CLGTTRGKA----------GAEGFVR---VDRDYVLKSAEL---AKAGGCKHFNLLSSKGADKSSNFL--YLQVKGEVEAKVEELKFD------RYSVFRPGVL---LCDRQESRPGEWLVRKFFGSLPDSWASGHSVPVVTVVRAMLNNVVRPRDKQMELLEDLGKAHGSLKP................................ 242
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.