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Query: sp|Q03426|KIME_HUMAN Mevalonate kinase OS=Homo sapiens GN=MVK PE=1 SV=1, from H.sapiens

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGLLast
1 -102.000sp|Q03426|KIME_HUMAN Mevalonate kinase OS=Homo sapiens GN=MVK PE=1 SV=1  ali  100  1MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL 396
2 -47.500sp|Q8N0W3|FUK_HUMAN L-fucose kinase OS=Homo sapiens GN=FUK PE=2 SV=2  ali   16  1...RARRIPEPELWL-----------AVGPRQDEMTVKIVCRCLADLRDYCQPHAPGALLKAAFICAGIVHVHSELQ---------------------------------------LSEQLLRTFGGGFELHTWSELPHGSGLGTSSILAGTALAALQRAAGRVVGT---------------EALIHAVLHLEQVLTTGGGWQDQVGGLMPGIKVGRSRA-EGFVQKLNDHLLLVYTGKTRLARNLLQDVLRSWYARLPAVVQNAHSLVRQTEECAEGFRQ-------GSLPLLGQCLTSYWEQLMAPGCEPLTVRRMMDVLAPHVHGQSLAGAGGGGFLYLLTKEPQQKEALEAVLAK..................................... 299
3 -41.500sp|P51570|GALK1_HUMAN Galactokinase OS=Homo sapiens GN=GALK1 PE=1 SV=1  ali follow..  22  27..EPELAVSAPGRVNLIGEHTDYNQGLVLPMALELMTVLVGSPRKDGLVSLLTTSEGADEPQRLQ--------------------------FPLPTAQRSLEPGTPRWANYVKGVIQYYPAAP--LPGFSAVVVSSVPLGGGLSSSASLEVATYTFLQQLCPDSGTIAA---------------RAQVCQQAEHSFAGMPCGIDQFISLMGQLIDCRSLETSLVPLSPKLAVLITNSNVRHSLASSEYPVRRRQEAARDLVSKEGFRRARHVVGEIRRTAQAAAALRRGDYRAFGRLMVESHRSLRDYEVSCPELDQLVEAALAVPYGSRMTGGGFGGCTVTLLEASAAPHAMRHIQEHYGGT--ATFYLSQAADGAKV................. 389
4 -41.400sp|Q01415|GALK2_HUMAN N-acetylgalactosamine kinase OS=Homo sapiens GN=GALK2 PE=1 SV=1  ali follow..  16  33..IPKFYVRAPGRVNIIGEHIDYCGYSVLPMAVEQDVLIAVEPVKTYALQLANTNPLYP-----------------------------DFSTSANNIQIDKTKPLWHNYFLCGLKGIQEHFGLSNLTGMNCLVDGNIPPSSGLSSSSALVCCAGLVTLTVLGRNLSKVE---------------LAEICAKSERYIGTEGGGMDQSISFLA-LIEFSPLRATDVKLPSGAVFVIANSCVEMNKEEMLLVTEDALHPEPYNPEEICRCLGKLYQRAKHVYSEAAEEAPENMVQLLGELMNQSHMSCRDYECSCPELDQLVDICRKFGQGSRLTGAGWGGCTVSMVPADKLPSFLANVHKAYYQR--QSLFATKPGGGALV................. 454
5 -35.900sp|Q8N0W3|FUK_HUMAN L-fucose kinase OS=Homo sapiens GN=FUK PE=2 SV=2  ali   18  24....................................................................................................................................................................................................................................NDHLLLVYTGKTRLARNLLQDVLRSWYARLPAVVQNAHSLVRQTEECAEGFRQ-------GSLPLLGQCLTSYWEQKKLMGCEPLTVRRMMDVLAPHVHGQSLAGAGGGGFLYLLTKEPQQKEALEALAKTEGLGNYSIHLVEVDTQGLSLKLLGTEAS......... 178
6 -23.000sp|Q8N0W3|FUK_HUMAN L-fucose kinase OS=Homo sapiens GN=FUK PE=2 SV=2  ali   14  103.PGQWVVAECPARVDFSGGWSDTLGGAVLGLAVRVDIGARARRIPEPELWLAVGPRQDEMTVKIVCRCLADLRDYCQPHAPGALLKAAFICAGIVHVHSE--------------LQLSEQLLRTFGGGFELHTWSELPHGSGLGTSSILAGTALAALQRAAGRVVGTEA---------------LIHAVLHLEQVL-TTGGGWDQVGGLMPGIKVGRS.................................................................................................................................................................................. 300
7 -11.400sp|P53602|MVD1_HUMAN Diphosphomevalonate decarboxylase OS=Homo sapiens GN=MVD PE=1 SV=1  ali follow..  16  1MASEAVTCTAPVNIAVIGEELVLPINSSLSVTLHLKTTTTAVISKDFT-------------------DRIWLNGREEDVGQPRLQACLREIRCLARKRRNSRDGDP--------------LPSSLSCKVHVASVNNFPTAAGLASSAAGYACLAYTLARVYG---------------VESDLSEVARR---------GSGSA---CRSLYGGFVEWQMGQVAPESHWPELRVLILVVSAEKKLTGSTVGMRASVETSPLLRFRAESVVPARMAEMARCIRE-------RDFPSFAQLTMKDSNQFHATCLDTFRIIHLVHRFNAHHGDTKVA--DAGPNAVIFTLDDTVAEFVAAVWHGF.................................... 330
8 -5.780sp|Q8NDY3|ARHL1_HUMAN [Protein ADP-ribosylarginine] hydrolase-like protein 1 OS=Homo sapiens GN=ADPRHL1 PE=2 SV=1  ali follow..  15  127.............................................................................................................................................GSGFGAATKAMCIGLRYW------------------KPERLETLIEVSVECGRMTHNHPTGFLGSLCTALFVSFAAQGKPLVQWGRDMLRAVPLAEEYCRKTIRHTAEYQEHWFYFEAKWQFYLEERKISKDSENKAIFPDNYDAEEREYRKWSSEGRGGRRGHDAPMIAGNSWTELCHRAMFHGIAGCLFGLGLDLVPKGLYQDLEDKEKLEDLGAALYR.................................. 348
9 -5.510sp|P07305|H10_HUMAN Histone H1.0 OS=Homo sapiens GN=H1F0 PE=1 SV=3  ali follow..  13  1........................................................................................................................................................................................................................................MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNR------------AGSSRQSIQKYIKSHYKVGEN---ADSQIKLSIKRLVTTGVLKQTKGVGASG-SFRLAKSDEPKKSVAFKKTK..................................... 111
10 -5.400sp|Q96FZ7|CHMP6_HUMAN Charged multivesicular body protein 6 OS=Homo sapiens GN=CHMP6 PE=1 SV=3  ali follow..  11  7................................................................................................................................................................................................................................................RKKQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEG--GNECLNKMHQVMSIEEVERILDETQEAVEYQRQID---ELLAGSFTQEDEDAILEELSAI 163

FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.