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Query: sp|Q0VAA5|PLCX2_HUMAN PI-PLC X domain-containing protein 2 OS=Homo sapiens GN=PLCXD2 PE=1 SV=1, from H.sapiens

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLAVRKARRKLRMGTICSPNPSGTKTSSEVCNADWMASLPPHLHNLPLSNLAIPGSHDSFSYWVDEKSPVGPDQTQAIKRLARISLVKKLMKKWSVTQNLTFREQLEAGIRYFDLRVSSKPGDADQEIYFIHGLFGIKVWDGLMEIDSFLTQHPQEIIFLDFNHFYAMDETHHKCLVLRIQEAFGNKLCPACSVESLTLRTLWEKNCQVLIFYHCPFYKQYPFLWPGKKIPAPWANTTSVRKLILFLETTLSERASRGSFHVSQAILTPRVKTIARGLVGGLKNTLVHSNRWNSHGPSLLSQERSLast
1 -100.000sp|Q0VAA5|PLCX2_HUMAN PI-PLC X domain-containing protein 2 OS=Homo sapiens GN=PLCXD2 PE=1 SV=1  ali  100  1MLAVRKARRKLRMGTICSPNPSGTKTSSEVCNADWMASLPPHLHNLPLSNLAIPGSHDSFSYWVDEKSPVGPDQTQAIKRLARISLVKKLMKKWSVTQNLTFREQLEAGIRYFDLRVSSKPGDADQEIYFIHGLFGIKVWDGLMEIDSFLTQHPQEIIFLDFNHFYAMDETHHKCLVLRIQEAFGNKLCPACSVESLTLRTLWEKNCQVLIFYHCPFYKQYPFLWPGKKIPAPWANTTSVRKLILFLETTLSERASRGSFHVSQAILTPRVKTIARGLVGGLKNTLVHSNRWNSHGPSLLSQERS 305
2 -79.100sp|Q63HM9|PLCX3_HUMAN PI-PLC X domain-containing protein 3 OS=Homo sapiens GN=PLCXD3 PE=2 SV=2  ali follow..  48  2.....................ASSQGKNELKLADWMATLPESMHSIPLTNLAIPGSHDSFSFYIDEASPVGPEQPETVQNFVFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVFLDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFAQEVSLKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQASITERRKKGSFFISQVVLTPKASTVVKGVASGLRE--TITERALPAMMQWVRTQKP 285
3 -70.300sp|Q9NUJ7|PLCX1_HUMAN PI-PLC X domain-containing protein 1 OS=Homo sapiens GN=PLCXD1 PE=2 SV=1  ali follow..  30  1............MGGQVSASNSFSRLHCRNANEDWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISHEESRLLQLLALPCITRPVVLKWSVTQALDVTEQLDAGVRYLDLRIAHMLEGSEKLHFVHMVYTTALVEDTLTEISEWLERHPREVVILACRNFEGLSEDLHEYLVACIKNIFGDMLCPRG--EVPTLRQLWSRGQQVIVSYEDESSLRRH--ELWPGVPYWWGNRVKTEALIRYLETMKSC-GRPGGLFVAGINLTENLQYVLAHPSESLEKMTLPNL---PRLSAWVREQCP 289
4 -11.900sp|Q4KWH8|PLCH1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1 OS=Homo sapiens GN=PLCH1 PE=1 SV=1  ali   16  2............................................DQPLCNYYIASSHNTYLTGDQLLSQSKVDM---------------------------YARVLQEGCRCVEVDCWDGPDGEPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENH---SIQQQRKIAQYLKGIFGDKLDSVDTGECKQLPSPQSLKGKILV.............................................................................................. 141
5 -11.200sp|P51178|PLCD1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 OS=Homo sapiens GN=PLCD1 PE=1 SV=2  ali   12  1..............................................PLSHYLVSSSHNTYLLEDQLAGPSSTE---------------------------AYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENH---TLEQQRVMARHLHAILGPMLLRPLDGVTNSLPSPEQLKGKILLKGKKLGGLLPPGGEGGPEATVVSDEDEAAEMEDEAVRSRVQHKPKEDKLRLAQ......................................... 190
6 -11.200sp|Q86YW0|PLCZ1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1 OS=Homo sapiens GN=PLCZ1 PE=2 SV=1  ali   12  8............................................THPLNDYFISSSHNTYLVSDQLLGPSDLW---------------------------GYVSALVKGCRCLEIDCWDGAQNEPVVYHGYTLTSKLLFKTVIQAIHKYAFMTSDYPVVLSLENH---STAQQEVMADNLQATFGESLLDMLDDFPDTLPSPEALKFKILV.............................................................................................. 146
7 -11.000sp|P16885|PLCG2_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 OS=Homo sapiens GN=PLCG2 PE=1 SV=4  ali   17  15............................................NNPLSHYWISSSHNTYLTGDQLRSESSPEA---------------------------YIRCLRMGCRCIELDCWDGPDGKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEH---SVEQQRHMAKAFKEVFGDLLLKPTEASADQLPSPSQLREKIII.............................................................................................. 153
8 -10.800sp|P19174|PLCG1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 OS=Homo sapiens GN=PLCG1 PE=1 SV=1  ali   17  23............................................NNPLSHYWISSSHNTYLTGDQFSSESSLEA---------------------------YARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDH---SIAQQRNMAQYFKKVLGDTLLTKPEISADGLPSPNQLKRKILI.............................................................................................. 161
9 -10.600sp|Q9UPR0|PLCL2_HUMAN Inactive phospholipase C-like protein 2 OS=Homo sapiens GN=PLCL2 PE=1 SV=2  ali   18  129............................................KQPLSHYFINSSHNTYLIEDQFRGPSDITG---------------------------YIRALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENH---SIKQQKVMVQHMKKLLGDKLYTSPNVEESYLPSPDVLKGKILI.............................................................................................. 267
10 -10.600sp|Q8N3E9|PLCD3_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 OS=Homo sapiens GN=PLCD3 PE=1 SV=3  ali   15  40............................................NQPLAHYFISSSHNTYLTDSQIGGPSSTEA---------------------------YVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVVQAVRDHAFTLSPYPVILSLENH---GLEQQAAMARHLCTILGDMLVTQDSPNPEELPSPEQLKGRVLV.............................................................................................. 179
11 -10.600sp|Q15111|PLCL1_HUMAN Inactive phospholipase C-like protein 1 OS=Homo sapiens GN=PLCL1 PE=1 SV=3  ali   17  101............................................TQPLSHYYINASHNTYLIEDQFRGPADING---------------------------YIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNH---SLPQQKVMAQQMKKVFGNKLYEAPLPSESYLPSPEKLKRMIIV.............................................................................................. 239
12 -10.500sp|Q9BRC7|PLCD4_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4 OS=Homo sapiens GN=PLCD4 PE=1 SV=1  ali   15  143............................................TQPLNHYFICSSHNTYLVGDQLCGQSSVEG---------------------------YIRALKRGCRCVEVDVWDGPSGEPVVYHGHTLTSRILFKDVVATVAQYAFQTSDYPVILSLETH---SWEQQQTMARHLTEILGEQLLSTDGVLPTQLPSPEELRRKILV.............................................................................................. 282
13 -10.500sp|P51178|PLCD1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 OS=Homo sapiens GN=PLCD1 PE=1 SV=2  ali   14  149............................................GQPLSHYLVSSSHNTYLLEDQLAGPSSTEA---------------------------YIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENH---TLEQQRVMARHLHAILGPMLLRPLDGVTNSLPSPEQLKGKILL.............................................................................................. 287
14 -10.500sp|Q86YW0|PLCZ1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1 OS=Homo sapiens GN=PLCZ1 PE=2 SV=1  ali   12  158............................................THPLNDYFISSSHNTYLVSDQLLGPSDLWG---------------------------YVSALVKGCRCLEIDCWDGAQNEPVVYHGYTLTSKLLFKTVIQAIHKYAFMTSDYPVVLSLENH---STAQQEVMADNLQATFGESLLSDMDDFPDTLPSPEALKFKILV.............................................................................................. 296
15 -10.400sp|Q9NQ66|PLCB1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 OS=Homo sapiens GN=PLCB1 PE=1 SV=1  ali   15  19............................................SQPLSHYFINSSHNTYLTAGQLAGNSSVEM---------------------------YRQVLLSGCRCVELDCWKGRTAEEEPV-ITHGFTMTTFKEVIEAIAECAFKTSPFPILLSFEN-HVDSPKQQAKMAEYCRLIFGDALLMEPLESGVPLPSPMDLMYKILV.............................................................................................. 164
16 -10.200sp|O75038|PLCH2_HUMAN(removed signalp:1-33) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-2 OS=Homo sapiens GN=PLCH2 PE=2 SV=3  ali   17  146............................................TQPLSHYFITSSHNTYLVGDQLMSQSRVDM---------------------------YAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENH---SVIQQKKMAQYLTDILGDKLDLSSSEDATTLPSPQMLKGKILV.............................................................................................. 285
17 -10.100sp|Q00722|PLCB2_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 OS=Homo sapiens GN=PLCB2 PE=1 SV=2  ali   17  15............................................TQPLNHYFINSSHNTYLTAGQFSGLSSAEM---------------------------YRQVLLSGCRCVELDC-WKGKPPDEEPIITHGFTMTTFKEAIEAIAESAFKTSPYPIILSFEN-HVDSPRQQAKMAEYCRTIFGDMLLTEPLKPGVPLPSPEDLRGKILI.............................................................................................. 160
18 -10.100sp|Q9P212|PLCE1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1 OS=Homo sapiens GN=PLCE1 PE=1 SV=3  ali   16  45............................................QLPLSYYYIESSHNTYLTGHQLKGESSVEL---------------------------YSQVLLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH---SLPQQRKMAEIFKTVFGEKLVTKDFSDDPMLPSPDQLRKKVLL.............................................................................................. 187
19 -10.100sp|Q4KWH8|PLCH1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1 OS=Homo sapiens GN=PLCH1 PE=1 SV=1  ali   16  152............................................DQPLCNYYIASSHNTYLTGDQLLSQSKVDM---------------------------YARVLQEGCRCVEVDCWDGPDGEPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENH---SIQQQRKIAQYLKGIFGDKLDSVDTGECKQLPSPQSLKGKILV.............................................................................................. 291
20 -10.100sp|Q15147|PLCB4_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens GN=PLCB4 PE=1 SV=3  ali   17  16............................................DHPLAHYFISSSHNTYLTGRQFGGKSSVEM---------------------------YRQVLLAGCRCVELDCWDGKGEDQEPI-ITHGKAMCTFKDVIQAIKETAFVTSEYPVILSFENH---SKYQQYKMSKYCEDLFGDLLLKQPLEPGRALPSPNDLKRKILI.............................................................................................. 160
21 -10.000sp|P19174|PLCG1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 OS=Homo sapiens GN=PLCG1 PE=1 SV=1  ali   17  173............................................NNPLSHYWISSSHNTYLTGDQFSSESSLEA---------------------------YARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDH---SIAQQRNMAQYFKKVLGDTLLTK.................................................................................................................. 290
22 -9.990sp|Q01970|PLCB3_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 OS=Homo sapiens GN=PLCB3 PE=1 SV=2  ali   17  20............................................TQPLSAYFINSSHNTYLTA----------------------------GQLAGTSSVEMYRQLLWGCRCVELDVWKGRPPEEEPF-ITHGFTMTTLRDVLEAIAETAFKTSPYPVILSFEN-HVDSAKQQAKMAEYCRSIFGDALLIEPLAPGVPLPSPQDLMGRILV.............................................................................................. 165
23 -9.960sp|P16885|PLCG2_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 OS=Homo sapiens GN=PLCG2 PE=1 SV=4  ali   19  165............................................NNPLSHYWISSSHNTYLTGDQLRSESSPEA---------------------------YIRCLRMGCRCIELDCWDGPDGKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEH---SVEQQRHMAKAFKEVFGDLLLTK.................................................................................................................. 282
24 -9.760sp|Q9BRC7|PLCD4_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4 OS=Homo sapiens GN=PLCD4 PE=1 SV=1  ali   15  1....................................................ICSSHNT--YLVGDQLC-------------------------GQSSVEGYIRALKRGCRCVEVDVWDGPSGEPVVYHGHTLTSRILFKDVVATVAQYAFQTSDYPVILSLETH---SWEQQQTMARHLTEILGEQLLTLDGVLPTQLPSPEELRRKILV.............................................................................................. 132
25 -9.630sp|O75038|PLCH2_HUMAN(removed signalp:1-33) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-2 OS=Homo sapiens GN=PLCH2 PE=2 SV=3  ali   16  1.................................................HYFITSSHNTYLVGDQLMSQSRVDM---------------------------YAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENH---SVIQQKKMAQYLTDILGDKLDLSSSEDATTLPSPQMLKGKILV.............................................................................................. 135
26 -9.120sp|Q9NQ66|PLCB1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 OS=Homo sapiens GN=PLCB1 PE=1 SV=1  ali   15  169............................................SQPLSHYFINSSHNTYLTAGQLAGNSSVEM---------------------------YRQVLLSGCRCVELDCWKGRTAEEEPV-ITHGFTMTTFKEVIEAIAECAFKTSPFPILLSFEN-HVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGV....................................................................................................... 300
27 -9.080sp|Q01970|PLCB3_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 OS=Homo sapiens GN=PLCB3 PE=1 SV=2  ali   16  170............................................TQPLSAYFINSSHNTYLTAGQLAGTSSVEM---------------------------YRQALLWGCRCVELDVGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFEN-HVDSAKQQAKMAEYCRSIFGDALLIEPLDKYPLAPG........................................................................................................ 300
28 -9.060sp|Q00722|PLCB2_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 OS=Homo sapiens GN=PLCB2 PE=1 SV=2  ali   14  165............................................TQPLNHYFINSSHNTYLTAGQFSGLSSAEM---------------------------YRQVLLSGCRCVELDCGKPPDEEPIITHGFTMTTDIFFKEAIEAIAESAFKTSPYPIILSFEN-HVDSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGV....................................................................................................... 296

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Li Z, and Godzik A. Modeling and Analyzing Three-Dimensional Structures of Human Disease Proteins Pacific Symposium on Biocomputing 11:439-450(2006) [PDF]