current user: public

If you have questions about the server, please let us know.

Query: sp|Q63HM9|PLCX3_HUMAN PI-PLC X domain-containing protein 3 OS=Homo sapiens GN=PLCXD3 PE=2 SV=2, from H.sapiens

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320
# Score Template Links and tools%idFirst MASSQGKNELKLADWMATLPESMHSIPLTNLAIPGSHDSFSFYIDEASPVGPEQPETVQNFVSVFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVFLDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFAQEVSLKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQASITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWVRTQKPGESGINIVTADFVELGDFISTVIKLNYVFDEGEANTLast
1 -104.000sp|Q63HM9|PLCX3_HUMAN PI-PLC X domain-containing protein 3 OS=Homo sapiens GN=PLCXD3 PE=2 SV=2  ali  100  1MASSQGKNELKLADWMATLPESMHSIPLTNLAIPGSHDSFSFYIDEASPVGPEQPETVQNFVSVFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVFLDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFAQEVSLKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQASITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWVRTQKPGESGINIVTADFVELGDFISTVIKLNYVFDEGEANT 321
2 -80.400sp|Q9NUJ7|PLCX1_HUMAN PI-PLC X domain-containing protein 1 OS=Homo sapiens GN=PLCXD1 PE=2 SV=1  ali follow..  30  10.SFSRLHCRNANEDWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISHEESRLLQLLNKALPCITRPVVLKWSVTQALDVTEQLDAGVRYLDLRIAHMLEGSENLHFVHMVYTTALVEDTLTEISEWLERHPREVVILACRNFEGLSEDLHEYLVACIKNIFGDMLCPRG--EVPTLRQLWSRGQQVIVSYEDESSLRRH--ELWPGVPYWWGNRVKTEALIRYLETMKSCGRP-GGLFVAGINLTENLQYVLAHPSES-LEKMTLPNLPRLSAWVREQCPGPRCTNIIAGDFIGADGFVSDVIALNQKLLW..... 322
3 -79.100sp|Q0VAA5|PLCX2_HUMAN PI-PLC X domain-containing protein 2 OS=Homo sapiens GN=PLCXD2 PE=1 SV=1  ali follow..  48  22.SGTKTSSEVCNADWMASLPPHLHNLPLSNLAIPGSHDSFSYWVDEKSPVGPDQTQAIKRL--ARISLVKKLMKKWSVTQNLTFREQLEAGIRYFDLRVSSKPGDADQEIYFIHGLFGIKVWDGLMEIDSFLTQHPQEIIFLDFNHFYAMDETHHKCLVLRIQEAFGNKLCPACSVESLTLRTLWEKNCQVLIFYHCPFYKQYPFLWPGKKIPAPWANTTSVRKLILFLETTLSERASRGSFHVSQAILTPRVKTIARGLVGGLKNVHSNRWNSHGPSLLSQERS.................................... 305
4 -11.900sp|Q86YW0|PLCZ1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1 OS=Homo sapiens GN=PLCZ1 PE=2 SV=1  ali   8........................THPLNDYFISSSHNT--YLVSDQLL---------------------------GPSDLWGYVSALVKGCRCLEIDCWDGAQNEPVVYHGYTLTSKLLFKTVIQAIHKYAFMTSDYPVVLSLENH---STAQQEVMADNLQATFGESLLSDMLDDFPDLPSPEALKFKILVKNKKIGTLKETHERKGSDKRGDNQDKETGVKKLPGVMLFKKKKTRKLKIALALSDLVIYTKAEKFKSFQHSRLYQQFNENNSIGETQARKLSKLRVHEFIFHTYPKATRADSSMVALNFQ........ 286
5 -11.400sp|Q4KWH8|PLCH1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1 OS=Homo sapiens GN=PLCH1 PE=1 SV=1  ali   17  2........................DQPLCNYYIASSHN--TYLTGDQLL---------------------------SQSKVDMYARVLQEGCRCVEVDCWDGPDGEPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENH---SIQQQRKIAQYLKGIFGDKLDSVDTGECKQLPSPQSLKGKILV................................................................................................................................ 141
6 -11.400sp|P51178|PLCD1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 OS=Homo sapiens GN=PLCD1 PE=1 SV=2  ali   10  1..........................PLSHYLVSSSHNT--YLLEDQLA---------------------------GPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENH---TLEQQRVMARHLHAILGPMLLNRPLDGVTNLPSPEQLKGKILLKGKKLGGLLPPGGEGGPEATVVSDEDEAAEMEDEAVRSRVQHKPKEDKLRLAQELSD-EMASFSENRALRLLQESGNGFVRHNVGHLSRIYPAGWRTDIVALNF----QTPGPEMDVYQGRFQDNGAC 299
7 -10.700sp|Q8N3E9|PLCD3_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3 OS=Homo sapiens GN=PLCD3 PE=1 SV=3  ali   14  40........................NQPLAHYFISSSHN--TYLTDSQIG---------------------------GPSSTEAYVRAFAQGCRCVELDCWEGPGGEPVIYHGHTLTSKILFRDVVQAVRDHAFTLSPYPVILSLENH---GLEQQAAMARHLCTILGDMLVALDSPNPEELPSPEQLKGRVLV................................................................................................................................ 179
8 -10.600sp|P16885|PLCG2_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 OS=Homo sapiens GN=PLCG2 PE=1 SV=4  ali   13  15........................NNPLSHYWISSSHNT----LTGDQLRSESSPEAYIRC--------------------------LRMGCRCIELDCWDGPDGKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEH---SVEQQRHMAKAFKEVFGDLLLTKPTEASADLPSPSQLREKIII................................................................................................................................ 153
9 -10.500sp|Q9UPR0|PLCL2_HUMAN Inactive phospholipase C-like protein 2 OS=Homo sapiens GN=PLCL2 PE=1 SV=2  ali   15  129........................KQPLSHYFINSSHNTYLIEDQFRGPSDITG-----------------------------YIRALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENH---SIKQQKVMVQHMKKLLGDKLYTTSNVEESYLPSPDVLKGKILI................................................................................................................................ 267
10 -10.500sp|P19174|PLCG1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 OS=Homo sapiens GN=PLCG1 PE=1 SV=1  ali   15  23........................NNPLSHYWISSSHNT----LTGDQFSSESSLEAYARC--------------------------LRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDH---SIAQQRNMAQYFKKVLGDTLLTKPVEISADLPSPNQLKRKILI................................................................................................................................ 161
11 -10.500sp|Q9BRC7|PLCD4_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4 OS=Homo sapiens GN=PLCD4 PE=1 SV=1  ali   12  143........................TQPLNHYFICSSHN--TYLVGDQLCGQSSVEGYIRA---------------------------LKRGCRCVEVDVWDGPSGEPVVYHGHTLTSRILFKDVVATVAQYAFQTSDYPVILSLETH---SWEQQQTMARHLTEILGEQLLTLDGVLPTQLPSPEELRRKILV................................................................................................................................ 282
12 -10.500sp|Q15111|PLCL1_HUMAN Inactive phospholipase C-like protein 1 OS=Homo sapiens GN=PLCL1 PE=1 SV=3  ali   17  101........................TQPLSHYYINASHNTYLIEDQFRGPADING-----------------------------YIRALKMGCRSVELDVSDGSDNEPILCNRNNMTTHVSFRSVIEVINKFAFVASEYPLILCLGNH---SLPQQKVMAQQMKKVFGNKLYTEALPSESYLPSPEKLKRMIIV................................................................................................................................ 239
13 -10.300sp|Q9NQ66|PLCB1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 OS=Homo sapiens GN=PLCB1 PE=1 SV=1  ali   17  19........................SQPLSHYFINSSHNT----LTAGQLAGNSSVEMYRQV--------------------------LLSGCRCVELDC--RTAEEEPVITHGFTMTTESFKEVIEAIAECAFKTSPFPILLSFEN-HVDSPKQQAKMAEYCRLIFGDALLMEPLESGVPLPSPMDLMYKILV................................................................................................................................ 164
14 -10.200sp|P51178|PLCD1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1 OS=Homo sapiens GN=PLCD1 PE=1 SV=2  ali   12  149........................GQPLSHYLVSSSHN--TYLLEDQLAGPSSTEAYIRA---------------------------LCKGCRCLELDCWDGPNQEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENH---TLEQQRVMARHLHAILGPMLLNRPLDGVTNLPSPEQLKGKILL................................................................................................................................ 287
15 -10.200sp|Q86YW0|PLCZ1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1 OS=Homo sapiens GN=PLCZ1 PE=2 SV=1  ali   12  158........................THPLNDYFISSSHNTYLVSDQLLGPSDLWG-----------------------------YVSALVKGCRCLEIDCWDGAQNEPVVYHGYTLTSKLLFKTVIQAIHKYAFMTSDYPVVLSLENH---STAQQEVMADNLQATFGESLLSDMLDDFPDLPSPEALKFKILV................................................................................................................................ 296
16 -10.100sp|Q00722|PLCB2_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 OS=Homo sapiens GN=PLCB2 PE=1 SV=2  ali   17  15........................TQPLNHYFINSSHNT----LTAGQFSGLSSAEMYRQV--------------------------LLSGCRCVELDC--KPPDEEPIITHGFTMTTDFFKEAIEAIAESAFKTSPYPIILSFEN-HVDSPRQQAKMAEYCRTIFGDMLLTEPLKPGVPLPSPEDLRGKILI................................................................................................................................ 160
17 -10.100sp|O75038|PLCH2_HUMAN(removed signalp:1-33) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-2 OS=Homo sapiens GN=PLCH2 PE=2 SV=3  ali   18  146........................TQPLSHYFITSSHNTYLVGDQLMSQSRVDM-----------------------------YAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENH---SVIQQKKMAQYLTDILGDKLDSVSSEDATTLPSPQMLKGKILV................................................................................................................................ 285
18 -10.100sp|Q01970|PLCB3_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 OS=Homo sapiens GN=PLCB3 PE=1 SV=2  ali   17  20........................TQPLSAYFINSSHNT----LTAGQLAGTSSVEMYRQA--------------------------LLWGCRCVELDV--RPPEEEPFITHGFTMTTEPLRDVLEAIAETAFKTSPYPVILSFEN-HVDSAKQQAKMAEYCRSIFGDALLIEPLAPGVPLPSPQDLMGRILV................................................................................................................................ 165
19 -10.100sp|Q4KWH8|PLCH1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1 OS=Homo sapiens GN=PLCH1 PE=1 SV=1  ali   18  152........................DQPLCNYYIASSHNTYLTGDQLLSQSKVDM-----------------------------YARVLQEGCRCVEVDCWDGPDGEPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENH---SIQQQRKIAQYLKGIFGDKLDSVDTGECKQLPSPQSLKGKILV................................................................................................................................ 291
20 -10.000sp|Q15147|PLCB4_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 OS=Homo sapiens GN=PLCB4 PE=1 SV=3  ali   17  16........................DHPLAHYFISSSHNT----LTGRQFGGKSSVEMYRQV--------------------------LLAGCRCVELDC--KGEDQEPIITHGKAMCTDLFKDVIQAIKETAFVTSEYPVILSFENH---SKYQQYKMSKYCEDLFGDLLLKQPLEPGRALPSPNDLKRKILI................................................................................................................................ 160
21 -10.000sp|Q9BRC7|PLCD4_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4 OS=Homo sapiens GN=PLCD4 PE=1 SV=1  ali   12  1................................ICSSHNT--YLVGDQLC---------------------------GQSSVEGYIRALKRGCRCVEVDVWDGPSGEPVVYHGHTLTSRILFKDVVATVAQYAFQTSDYPVILSLETH---SWEQQQTMARHLTEILGEQLLTLDGVLPTQLPSPEELRRKILV................................................................................................................................ 132
22 -9.930sp|Q9P212|PLCE1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1 OS=Homo sapiens GN=PLCE1 PE=1 SV=3  ali   15  45........................QLPLSYYYIESSHNT----LTGHQLKGESSVELYSQV--------------------------LLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENH---SLPQQRKMAEIFKTVFGEKLVTKDFSDDPMLPSPDQLRKKVLL................................................................................................................................ 187
23 -9.860sp|P19174|PLCG1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 OS=Homo sapiens GN=PLCG1 PE=1 SV=1  ali   16  173........................NNPLSHYWISSSHNT----LTGDQFSSESSLEAYARC--------------------------LRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDH---SIAQQRNMAQYFKKVLGDTLL...................................................................................................................................................... 288
24 -9.790sp|P16885|PLCG2_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 OS=Homo sapiens GN=PLCG2 PE=1 SV=4  ali   15  165........................NNPLSHYWISSSHNT----LTGDQLRSESSPEAYIRC--------------------------LRMGCRCIELDCWDGPDGKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEH---SVEQQRHMAKAFKEVFGDLLL...................................................................................................................................................... 280
25 -9.790sp|Q9NQ66|PLCB1_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 OS=Homo sapiens GN=PLCB1 PE=1 SV=1  ali   15  169........................SQPLSHYFINSSHNT----LTAGQLAGNSSVEMYRQV--------------------------LLSGCRCVELDC--RTAEEEPVITHGFTMTTESFKEVIEAIAECAFKTSPFPILLSFEN-HVDSPKQQAKMAEYCRLIFGDALLMEPLEKYPLESGV......................................................................................................................................... 300
26 -9.480sp|Q01970|PLCB3_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3 OS=Homo sapiens GN=PLCB3 PE=1 SV=2  ali   16  170........................TQPLSAYFINSSHNT----LTAGQLAGTSSVEMYRQA--------------------------LLWGCRCVELDV--RPPEEEPFITHGFTMTTEPLRDVLEAIAETAFKTSPYPVILSFEN-HVDSAKQQAKMAEYCRSIFGDALLIEPLDKYPLAPG.......................................................................................................................................... 300
27 -9.320sp|O75038|PLCH2_HUMAN(removed signalp:1-33) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-2 OS=Homo sapiens GN=PLCH2 PE=2 SV=3  ali   17  1.............................HYFITSSHNT----LVGDQLMSQSRVDMYAWV--------------------------LQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENH---SVIQQKKMAQYLTDILGDKLDSVSSEDATTLPSPQMLKGKILV................................................................................................................................ 135
28 -9.290sp|Q00722|PLCB2_HUMAN 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 OS=Homo sapiens GN=PLCB2 PE=1 SV=2  ali   16  165........................TQPLNHYFINSSHNT----LTAGQFSGLSSAEMYRQV--------------------------LLSGCRCVELDC--KPPDEEPIITHGFTMTTDFFKEAIEAIAESAFKTSPYPIILSFEN-HVDSPRQQAKMAEYCRTIFGDMLLTEPLEKFPLKPGV......................................................................................................................................... 296

FFAS is supported by the NIH grant R01-GM087218-01
1 4 3 0 4 3   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zhang Y, Stec B, Godzik A. Between order and disorder in protein structures: analysis of "dual personality" fragments in proteins. Structure. 2007 Sep;15(9):1141-7.