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Query: sp|Q6NUM9|RETST_HUMAN(removed signalp:1-18) All-trans-retinol 13,14-reductase OS=Homo sapiens GN=RETSAT PE=2 SV=2, from H.sapiens

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst KVYLGLFSGSSPNPFSEDVKRPPAPLVTDKEARKKVLKQAFSANQVPEKLDVVVIGSGFGGLAAAAILAKAGKRVLVLEQHTKAGGCCHTFGKNGLEFDTGIHYIGRMEEGSIGRFILDQITEGQLDWAPLSSPFDIMVLEGPNGRKEYPMYSGEKAYIQGLKEKFPQEEAIIDKYIKLVKVVSSGAPHAILLKFLPLPVVQLLDRCGLLTRFSPFLQASTQSLAEVLQQLGASSELQAVLSYIFPTYGVTPNHSAFSMHALLVNHYMKGGFYPRGGSSEIAFHTIPVIQRAGGAVLTKATVQSVLLDSAGKACGVSVKKGHELVNIYCPIVVSNAGLFNTYEHLLPGNARCLPGVKQQLGTVRPGLGMTSVFICLRGTKEDLHLPSTNYYVYYDTDMDQAMERYVSMPREEAAEHIPLLFFAFPSAKDPTWEDRFPGRSTMIMLIPTAYEWFEEWQAELKGKRGSDYETFKNSFVEASMSVVLKLFPQLEGKVESVTAGSPLTNQFYLAAPRGACYGADHDLGRLHPCVMASLRAQSPIPNLYLTGQDIFTCGLVGALQGALLCSSAILKRNLYSDLKNLDSRIRAQKKKNLast
1 -145.000sp|Q6NUM9|RETST_HUMAN(removed signalp:1-18) All-trans-retinol 13,14-reductase OS=Homo sapiens GN=RETSAT PE=2 SV=2  ali  100  1KVYLGLFSGSSPNPFSEDVKRPPAPLVTDKEARKKVLKQAFSANQVPEKLDVVVIGSGFGGLAAAAILAKAGKRVLVLEQHTKAGGCCHTFGKNGLEFDTGIHYIGRMEEGSIGRFILDQITEGQLDWAPLSSPFDIMVLEGPNGRKEYPMYSGEKAYIQGLKEKFPQEEAIIDKYIKLVKVVSSGAPHAILLKFLPLPVVQLLDRCGLLTRFSPFLQASTQSLAEVLQQLGASSELQAVLSYIFPTYGVTPNHSAFSMHALLVNHYMKGGFYPRGGSSEIAFHTIPVIQRAGGAVLTKATVQSVLLDSAGKACGVSVKKGHELVNIYCPIVVSNAGLFNTYEHLLPGNARCLPGVKQQLGTVRPGLGMTSVFICLRGTKEDLHLPSTNYYVYYDTDMDQAMERYVSMPREEAAEHIPLLFFAFPSAKDPTWEDRFPGRSTMIMLIPTAYEWFEEWQAELKGKRGSDYETFKNSFVEASMSVVLKLFPQLEGKVESVTAGSPLTNQFYLAAPRGACYGADHDLGRLHPCVMASLRAQSPIPNLYLTGQDIFTCGLVGALQGALLCSSAILKRNLYSDLKNLDSRIRAQKKKN 592
2 -92.400sp|Q8N2H3|PYRD2_HUMAN Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 OS=Homo sapiens GN=PYROXD2 PE=2 SV=2  ali follow..  15  2................AASGRGLCKAVAASPFPAWRRDNTEARGGLKPEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFERRHVIGGAAVTEEIPGFKFSRASYLLSLLRPQELKKHGLRLHLRNPYSFTPMLEEGAGS-----KVPRCLLLGTDMAENQKQIAQFSQKDAQVFPKYEEFMHRLALAIDPLLDAAPVDMAAFQHGSLLQRMRSLPRYYEVLTAPITKVLDQWFESEPLKATLATDAVIGAMTSPHTPGSGYVLLHHVMGGAWGYVQGGMGALSDAIASSATTHGASIFTEKTVAKVQVNSEGCVQGVVLEDGT---EVRSKMVLSNTSPQITFLKLTPQE-WLPEEFLERISQLDTRSPVTKINVAVDRLPSFLAAPNHQCSIHLNCEDTLLLHQAFEDAMDGLPSHRPVIELCIPSSLDPTLAPP--GCHVVSLFTQYMPYTLAG--------GKAWDEQERDAYADRVFDCIEVYAPGFKDSVVGRDILTPPDLERIFGLPGGNIFHCAMSLDQLYFARPLHSGYRCPLQGLYLCGSGAHPGGGVMGA-AGRNAAHVAFRD.................... 577
3 -32.500sp|P21397|AOFA_HUMAN Amine oxidase [flavin-containing] A OS=Homo sapiens GN=MAOA PE=1 SV=1  ali follow..  12  1....................................MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIREHVDYVDVGGAYVGPTQN-----RILRLSKELGIETYKVNVSERLVQYVKGKT---------YPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPT------------------DAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVINVTSEPHEVSALWFLIFSVTNGGQERKFVGGSGQVSERIMDLL---GDQVKLNHPVTHVDQSSDNII--IETLNHE---HYECKYVINAIPP--TLTAKIHFRPELPAERNQLIQRLPMG-AVIKCMMYYKEAF------------------------------KKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLH-----------KEIRKKKICELYAKVLGS-------QEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETWSGYMEGAVEAGERAAREVLNG.................... 462
4 -32.200sp|P27338|AOFB_HUMAN Amine oxidase [flavin-containing] B OS=Homo sapiens GN=MAOB PE=1 SV=3  ali follow..  13  1.............................................MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRQKVKYVDLGGSYVGPTQN-----RILRLAKELGLETYKVNEVERLIHH------------VKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWD---------------NMTMKELLDKLCWTESAKQLATLFVLCVTAETHEVSALWFLIISTTNGGQERKFVGGSGQVSERIMDLL---GDRVKLERPVIYIDQTRENVL--VETLNHE---MYEAKYVISAIPP--TLGMKIHFNPPLPMMRNQMITRVPLG-SVIKCIVYYKEPF------------------------------RKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLT-----------KEERLKKLCELYAKVLGS-------LEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVD.. 471
5 -31.700sp|Q96RQ9|OXLA_HUMAN(removed signalp:1-21) L-amino-acid oxidase OS=Homo sapiens GN=IL4I1 PE=1 SV=1  ali follow..  14  1...........QDWKAERSQDPFEKCMQDPDYEQLLKVVTWGLNRTLKPQRVIVVGAGVAGLVAAKVLSDAGHKVTILEADNRIGGRIFTYRNTGWIGELGAMRMPSSHR----------------ILHKLCQGLGLNLTKFTQYDKNTWTEVHEVKLRNYVVEKVPEKLG---------YALRPQEKGHSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLGEGNLSRPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLSSL---SGLVLLNAPVVAMTQGPHDVHVQIETSPARNLKVLKADVVLLTASG--PAVKRITFSPPLPRHMQEALRRLHYV-PATKVFLSFRRP----------------------FWREEHIEGGHSNTDRPSRMIFYPPPREGA----------LLLASYTWSDAAAAFAGLS-----------REEALRLALDDVAALHGPVVRQLWDGTGVVQHSQGGFVVQPPALWQTEKDDWTV-------------PYGRIYFAGEHTAHGWVETAVKSALRAAIKINSRKGPASDTASPEGHASDMEGQ 506
6 -29.600sp|P50395|GDIB_HUMAN Rab GDP dissociation inhibitor beta OS=Homo sapiens GN=GDI2 PE=1 SV=2  ali follow..  11  1.............................................MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRGRDWNVDLIPKFL--MANGQLVKMLLYTEVTRYLDFKVTEGSFVYKGGKIYKVPSTEAEALA---------SSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALALYRTDDYLDQIKLYSESLARYGKSPYYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNG-KVIGVKSEGEI----ARCKQLICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKS-----------------DIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATETTCDDIKNIYKRM...................................................................................................... 424
7 -29.400sp|P26374|RAE2_HUMAN Rab proteins geranylgeranyltransferase component A 2 OS=Homo sapiens GN=CHML PE=1 SV=2  ali   10  2..........................................ADNLPTEFDVVIIGTGLPESILAAACSRSGQRVLHIDSRSYYGGNWASFSFSGLLSWLKEYQQNNDIGEESTVVWQDLIHETEEAITLRKKDETI-----QHTEAFCYASQDMEDNVEEIGALQKNPSLGVSNTFTEVLDSALPEESQLSYFNSDEMPAKHTQKSDTEISLEVTDVEESVEKEKYCGDKTCMHTVSDKDGDKDESKSTVEDKADEPIRNRITYSQIVKEGKLLYSQGLLIDLL---IKSDVSRYVEFKNVTRILAFREGKVEQVPCSRAD----VFNSKELTMVEKRMLMK......................................................................................................................................................................................................................................................... 299
8 -29.300sp|Q9UHG3|PCYOX_HUMAN(removed signalp:1-27) Prenylcysteine oxidase 1 OS=Homo sapiens GN=PCYOX1 PE=1 SV=3  ali follow..  11  1..........................................AELRAPPDKIAIIGAGIGGTSAAYYLRQKDVKIDLFER-EEVGGRLATMMVQGQEYEAGGSVIHPLNL-----HMKRFVKDLGLSAVQASGGLLGIY-----NGETLVFEESNWFIINVIKLVW-RYGFQSLRMHMWVEDVLDKFMRIYRYQSHDYAFSSVEKLLHALG-GDDFLGMLNRTLLETLQK-FSEKFLNEMIAPVMRVNYGQSTDINAFVGAVSLSCSDSGLWAVEGGNKLVCSGL---LQASKSNLISGSVMYIEEKTKTKKMYEVVYQIGTETRSDFYDIVLVATPLNRKMSNITFLNFDPP---IEEFHQYYQHIVTTLVKGELNTS-----------IFSSRPIDKFGLNTVLTTDNSDLFINSIGIVPSVREKEDPEPSTDGTYVWKIFSQETLTKAQILKLFLSYDYAVKKPWLAYPHYKPPEKCPSII--------------------------------------------------------DRLYYLNGIECAASAMMSAIAAHNAALLAY-HRWNGHTDMIDQDGLYEKLKT 476
9 -29.200sp|Q8NBM8|PCYXL_HUMAN(removed signalp:1-22) Prenylcysteine oxidase-like OS=Homo sapiens GN=PCYOX1L PE=1 SV=2  ali follow..  13  2..............................................APPGKIAVVGAGIGGSAVAHFLQQPRVQIDVYEKG-TVGGRLATISVNKQHYESGAASFHSLSL-----HMQDFVKLLGLRHRREVVGRSAIF-----GGEHFMLEETDWYLLNLFRLWW-HYGISFLRLQMWVEEVMEKFMRIYKYQAHGYAFSGVEELLYSLGE-STFVNMTQHSVAESLLQVVTQRFIDDVVSAVLRASYGQSAAMPAFAGAMSLAGAQGSLWSVEGGNKLVCSGL---LKLTKANVIHATVTSVTLHSTEGALYQVAYENEVGNSSDFYDIVVIATPLHLDNSSSNLTFAGFHPPIDDVQGSFQPTVVSLV---------------------------HGYLNSSYFGFPDPKLFPFANILTTDFPSFFCTLDNICPVNISASF----------------RRKQPQEAAVWRVQSPKPLFRTLKTLFRSYYSVQTAEWQAHP-------------LYGSRPTLPRFALH-----------DQLFYLNAEWAASSVEVMAVAAKNVALLAY-NRWYQDLDKIDQKDLMHKVKT 470
10 -29.100sp|P31150|GDIA_HUMAN Rab GDP dissociation inhibitor alpha OS=Homo sapiens GN=GDI1 PE=1 SV=2  ali follow..  11  1.............................................MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLEGPPESMGRGRDWNVDLIPKFL--MANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVPSTETEALA---------SNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQDVIDFTGHALALYRTDDYLDQIKLYSESLARYGKSPYYPLYGLGELPQGFARLSAIYGGTYMLNKPVDDIIMENG-KVVGVKSEGEV----ARCKQLICDPSYIPDRVRKAGQVIRIICILSHPIKNTNDANSCQIIIPQNQVNRKS-----------------DIYVCMISYAHNVAAQGKYIAIASTTVETTDPEKEVEPALELLEPIDQKFVAISDLYEPIDDGCESQVFCSCSYDATETTCNDIKDIYKRM...................................................................................................... 424
11 -27.400sp|Q6QHF9|PAOX_HUMAN Peroxisomal N(1)-acetyl-spermine/spermidine oxidase OS=Homo sapiens GN=PAOX PE=1 SV=3  ali   11  1...............................................PVPSVGEYLKKEIGQHVARLCGHSAFPLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGL--LGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQL----------VAEMATLFYGLIDQTREFLHAAETPV---------------PSVGEYLKKEIGQHVAGWTEDEETRKLFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPE--DTVVFEKPVKTIAFPGETFPVSVECEDGD---RFPAHHVIVTVPLDTFFDPPLPAEKA................................................................................................................................................................................................................................................. 297
12 -25.000sp|Q9NWM0|SMOX_HUMAN Spermine oxidase OS=Homo sapiens GN=SMOX PE=1 SV=1  ali follow..  10  5.............................ESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFDVTVLEASSHIGGRVQSVKLGHATFELGATWIHGSH-GNPIYHLAEANGLLEETTDGERSVGRISLYSKNGVACYLTNHGRRKDVVEEFSDLYNEVYNLTQEFFRHDKPVNAESQ-------------------------NSVGVFTREEVRNRIRNDPDDPEIQQYLKVESCESSSHSMDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPAH--VIQLGKPVRCIHDEDEQWSVVVECEDCE---LIPADHVIVTVSLGVLKRQYTS-RPGLPTEKVAAIHRLGIGT---KIFLEFEEP-------------FWGPECNSLQFVWEDEAESHTLTYPPELWYRKICGFDVLYPPERYGHVLSGWICGEEALVMEKCDD--------------EAVAEICTEMLRQFTPKPRRILRSAWGSNPYFRGSYSYTQVGSS---GADVEKLAKPLPYTESSKTAPMQVLFSGEATYYSTTHGALLSGQREAARLIE..................... 545
13 -24.900sp|P50336|PPOX_HUMAN Protoporphyrinogen oxidase OS=Homo sapiens GN=PPOX PE=1 SV=1  ali follow..  15  2................................................GRTVVVLGGGISGLAASYHLSRAPPKVVLVESSERLGGWIRSVRPNGAIFELGP---------------------------------RGIRPAGALGARTLLLVSELG-LDSEVLPVRGDHPAAQNRFLYVGGALHALPTGLRGLLRPSPPFSKPLFWAGLRELTKPRGKEPDETVHSFAQRRLGPEVASLAMDLCRGVFAGNSRELSSCFPSLFQAEQTHRSWSLRGGLEMLPQALETHLTSRGVSVLRGQPVCGLSLQAEGRWKVSLRDS-----SLEADHVISAI-PASVLSELLPAEAAPLARALSAIT----AVSVAVVNLQYQG--AHLPVQGFGHLV-------------------PSSEDPGVLGIVYDSVAFPEQDGSPPGLRVTVML--------SWLQTLEASGCVLSQELFQQRAQEAAATQLGLKEMPSHCLVHLHKNCIP-----------------QYTLGHWQKLESARQFLTAHRLPLTLAGASYEGVAVNDCIESGRQAAVSVLGT.................... 473
14 -24.300sp|Q6QHF9|PAOX_HUMAN Peroxisomal N(1)-acetyl-spermine/spermidine oxidase OS=Homo sapiens GN=PAOX PE=1 SV=3  ali   15  1....................................MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGL--LGEKELSQENQLVETGGHVGLPSVSYASSGTSVSLQLVAEM---ATLFYGLIDQTREFLHA------------------------------AETPVPSVGEYLKKEIGQHVARLCGHSAFPHLRVLEATARAGGRIRSEVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMATFYGLIDQTREFLHAAETPVPSVGEYLKK...................................................................................................................................................................................................................................... 299
15 -24.100sp|P24386|RAE1_HUMAN Rab proteins geranylgeranyltransferase component A 1 OS=Homo sapiens GN=CHM PE=1 SV=3  ali   9  2...............................................EMLTEQTPSSDPENALEVNGAEVTGEKENHCDDKTCVPSTSAEDEGRRFNIDLVSKLL--YSRGLLIDLLIKSNVSRYAEFKNITRIL--------REGRVEQVPCSRADVFNS-KQLTMVEKRMLMKFLTFCMEYEKYP--------------------------DEYKGYEEITFYEYLKTQKLTPNLQYIVMHSIAMTSETASSTIDGLKATKNFLHCLGRYFPLYGQGELPQCFCRMCAVFGGIYCLRHSVQCLVVDESRKCKAIIDQFGQR---IISEHFLVEDS............................................................................................................................................................................................................................................................... 287
16 -23.200sp|P24386|RAE1_HUMAN Rab proteins geranylgeranyltransferase component A 1 OS=Homo sapiens GN=CHM PE=1 SV=3  ali   12  2..........................................ADTLPSEFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFSFSGLLSWLKEYQENSDIVSDSPVWQDQILENEEA--IALSRKDKTIQHVEVFCYASQDLHEDVEEAGALQKNHALVTSAN-ADSAFLPTEDESLSTMSCEMLTEQTPSSDPENALEVNGAEVTGEKENHCDDKTCVPSTSAEDMSENVPIAEDTTEQPKKNRITYSQIIKEGRRFNIDLVKLLYSRGLLIDLL---IKSNVSRYAEFKNITRILAFREGRVEQVPCSRAD----VFNSKQLTMVE-KRMLMKFLT..................................................................................................................................................................................................................................................... 300
17 -21.700sp|Q8NB78|KDM1B_HUMAN Lysine-specific histone demethylase 1B OS=Homo sapiens GN=KDM1B PE=1 SV=3  ali   14  68..................................SVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSKGVTVGRGAQIVNGCIN----NPVALMCEQLGISMHKFGERCDLIQEGG-------------RITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKE------------------SGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHFFAQFAGDHTLLTPGYSVIIEKLAEGL-----DIQLKSPVQC................................................................................................................................................................................................................................................................................................ 300
18 -20.900sp|O60341|KDM1A_HUMAN Lysine-specific histone demethylase 1A OS=Homo sapiens GN=KDM1A PE=1 SV=2  ali   19  121.........................................KPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLG-GNPMAVVSKQVN---MELAKIKQKCPLYEANGQPKEKDEMVEQEFNRLLEATSYLSNNKPVSLGQALEVVIQ.......................................................................................................................................................................................................................................................................................................................................................................................................................... 267
19 -20.400sp|Q9UL12|SARDH_HUMAN Sarcosine dehydrogenase, mitochondrial OS=Homo sapiens GN=SARDH PE=1 SV=1  ali   17  47.............................KEGQGTSVVAQGPSRPLPSTANVVVIGGGSLGCQTLYHLAKLGMSAVLLERERLTSGTTW-------------------HTAGLLWQLRPSDVEVELLAHTRRVVSREL-------EEETGLHTGWIQNGGLFIASNRQRLDEYKRLMSLGKAYGVESHVL------------------------------------------------------------SPAETKTLYPLMNVDDLYGTLYVPHDGTAGTCTTLARAASARGAQVIENCPVTGIRVWTDDRVAGVETQHGS----IQTPCVVNCAGV.............................................................................................................................................................................................................................................................. 273
20 -19.800sp|P26374|RAE2_HUMAN Rab proteins geranylgeranyltransferase component A 2 OS=Homo sapiens GN=CHML PE=1 SV=2  ali   10  3......................................................MPAKHTQKSDTEISLEVTDVEESVEKEKYCGDKTCMHTGRRFNIDLVSKLL--YSQGLLIDLLIKSDVSRYVEFKNVTRILAF------REGKVEQVPCSRADVFNS-KELTMVEKRMLMKFLTFCLEYEQHP--------------------------DEYQAFRQCSFSEYLKTKKLTPNLQHFVLHSIAMTSESSCTTIDGLNATKNFLQCLGRFFPLYGQGEIPQGFCRMCAVFGGIYCLRHKVQCFVVKESGRCKAIIDHFGQR---INAKYFIVEDS............................................................................................................................................................................................................................................................... 289
21 -19.200sp|Q9UI17|M2GD_HUMAN(removed signalp:1-23) Dimethylglycine dehydrogenase, mitochondrial OS=Homo sapiens GN=DMGDH PE=1 SV=2  ali   16  9...............................REGEEKPPLSAETQWKDRAETVIIGGGCVGVSLAYHLAKAGMKVVLLEKSELTAGSTW-------------------HAAGLTTYFHPGINLKKIHYDSIKLYEKL--------EEETGQVVGFHQPGSIRLATTPVRVDEFKYQMTRTGWHATEQYLI------------------------------------------------------------EPEKIQEMFPLLNMNKVLAGLYNPGDGHYSLTMALAAGARKCGALLKYPAPVTSLKARSD-GTWDVETPQGS----MRANRIVNAAGF.............................................................................................................................................................................................................................................................. 227
22 -19.200sp|Q8NCN5|PDPR_HUMAN Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial OS=Homo sapiens GN=PDPR PE=1 SV=2  ali   18  13...................QRASPGWQNWSSARNSTSAAEARSMALPTQAQVVICGGGITGTSVAYHLSKMGWKIVLLEQGRLAAGSTR-------------------FCAGILSTARHLTIEQKMADYSNKLYYQL--------EQETGIQTGYTRTGSIFLAQTQDRLISLKRINAGLNVIGIPSEII------------------------------------------------------------SPKKVAELHHLLNVHDLVGAMHVPEDASADVALALASAASQNGVQIYDRTSVLHVMVKKG-QVTGVETDKGQ----IECQYFVNCAGQ.............................................................................................................................................................................................................................................................. 243
23 -18.500sp|Q9P0Z9|SOX_HUMAN Peroxisomal sarcosine oxidase OS=Homo sapiens GN=PIPOX PE=2 SV=2  ali follow..  17  1..........................................MAAQKDLWDAIVIGAGIQGCFTAYHLAKHRKRILLLEQFFLPHSRGSSHGQSRI-----------------------------IRKAYLEDFYTRMMHECYQIWAQLEHEAGTQLHRQT-LLLGMKENQELKTIQANLSRQ------------------------------------------RVEHQCLSSEELKQRF-------------------NIRLPRGEVGLLDNSGGAYKALRALQDAIRQLGGIVRDGEKVVEI---NPGLLVTVKTTSRS----YQAKSLVITAGP---TNQLLRP-------------------------LGIEMPLQTL----RINVCYWREMVPGSYGVSQAFPCFLWLGLCPHHIYGLPTGEYPGLMKVSYHHG----------------NHADPEERDCPTARTDIGDVQILSSFVRDHLPDLKPEPAVIESCM------YTNTPDEQFI----------------LDRHPKYDNIVIGAGFS-GHGFKLAPVVGKILYELSMKLTPSYDLAPFRISRFPSLGKA 388
24 -18.200sp|Q8NB78|KDM1B_HUMAN Lysine-specific histone demethylase 1B OS=Homo sapiens GN=KDM1B PE=1 SV=3  ali   26  218..................................SVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSKGVTVGRGAQIVNGCI................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 293
25 -18.000sp|Q5VYX0|RNLS_HUMAN(removed signalp:1-17) Renalase OS=Homo sapiens GN=RNLS PE=2 SV=1  ali follow..  14  1..............................................................ALLRRQTSGPLYLAVWDKAEDSGGRMTT-HNPQCTADLGAQYITCTPH-------------------------------------------------------------------------------------------------------------YAKKHQRFYDELLAYGVLRPLSSPIEGMVMKEGDC-----------------FVAPQGISSIIKHY---LKESGAEVYFRHRVTQINLRDDK----VSKQTGSPEQ---FDLIVLTMPVPEILQLQGDITTLISECQRQQLEAVSYS-SRYALGLFYEAGTK------------------------VPWAGQYITSNPCIRFVSIDNKKRNIESSEIGPSLVIHT---------------TVPFGVTYLEHSIEDVQELVFQQLENILPGLPQPIAT------------------KCQKWRHSQVTNAAANCPGQMTLHHKPFLACGGDGFTQSNFDGCITSALCVLEALKNY.................... 324
26 -17.400sp|Q9Y2Z2|MTO1_HUMAN Protein MTO1 homolog, mitochondrial OS=Homo sapiens GN=MTO1 PE=1 SV=2  ali   24  3.............YFRGCGRWVAVSFTKQQFPLARLSSD--SAAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSC...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 77
27 -16.900sp|P43304|GPDM_HUMAN(removed signalp:1-23) Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Homo sapiens GN=GPD2 PE=1 SV=3  ali   14  4......FAHYRRKQMNLAYVKAADCISEPVNREPPSREAQLLTLQNTSEFDILVIGGGATGSGCALDAVTRGLKTALVERDDFSSGTSSRSTK----IHGGVRYL--------------QKAIMKLDI------------------EQYRMVKEALHERANLLEIAPHLSAPLPIMLPVYKWWQLPYYWVGI------------------------------KLYDLVAGSNCLKSSYVL----------SKSRALEHFPMLQKDKLVGAIVYYDGNDARMNLAIALTAARYGAATANYMEVVSLLKKTDPRVSGARCKDTGQEFDVRAKCVINATGP.............................................................................................................................................................................................................................................................. 269
28 -16.700sp|Q14534|ERG1_HUMAN(removed signalp:1-43) Squalene monooxygenase OS=Homo sapiens GN=SQLE PE=2 SV=3  ali follow..  14  39.......KSPPESENKEQLEARRRRKGTNISETSLIGTAACTSTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQ----PGGYHVLKDLGLGDTVEGL------------------------DAQVVNGYMIHDQESKSEVQIP--YPLSENNQVQSGRAFHH------------------------------------------------------------------------------------------------GRFIMSLRKAAMAEPNAKFIEGVVLQL-LEEDDVVMGVQYKDKEDIKELHAPLTVVADGLFSKFRKSLVSNKVSVSSH----------------FVGFLMKNAPQFKANHAELILANPSPVLIY-------------------------------QISSSETRVLVDI-----------------RGEMPRNLREYMVEKIYPQIP---DHLKEPFLEATDNSHLRSMPASFLPPSSVKK----------------------RGVLLLGDAYNM-GMTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWAR 415
29 -16.600sp|Q16134|ETFD_HUMAN Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens GN=ETFDH PE=1 SV=2  ali   12  25.....YLPLCATRWSSTSTVPRITTHYTIYPRDKDKRWEGVNMERFAEEADVVIVGAGPAGLSAAVRLKQKDIRVCLVEKAAQIGAHTLS---------------GACLDPGAFKELFPDWKEKGAPLNTPVTEDRFGILTEK----------------YRIPVPILPGLPMNNHGNYIVRL------------------------------------------------------------------------------------------------GHLVSWMGEQAEALGVEVYPGYAAAEVLFHDDGSVKGIATNDVERGLELHAKVTIFAEGCHGHLAKQLYKKFDLRANCEPQ......................................................................................................................................................................................................................................... 269
30 -16.000sp|Q8IWF2|FXRD2_HUMAN(removed signalp:1-26) FAD-dependent oxidoreductase domain-containing protein 2 OS=Homo sapiens GN=FOXRED2 PE=1 SV=1  ali   15  1.............................................VPPRRDYCVLGAGPAGLQMAYFLQRAGRDYAVFERAPRPGSFFTRYPRHRKLISINKRYTGKANAEFNLRHDWNSLLSHDPRLL----------------------------FRHYSRAYFPDARD-------------------------------------------------------------------------------------------------------------MVRYLGDFADTLGLRVQYNTTIAHVTLDKDRQAWNGHYLTDQKGQVHQCSVLFVATGLSVPNQVDFPGSEYAEGYESVSVDPEDFVGQNVLI-LGRGNSAFET................................................................................................................................................................................................................. 202
31 -15.700sp|Q96CU9|FXRD1_HUMAN FAD-dependent oxidoreductase domain-containing protein 1 OS=Homo sapiens GN=FOXRED1 PE=1 SV=2  ali follow..  13  31................DGKVSEIKKKIKSILPGRSCDLLQDTSHLPPEHSDVVIVGGGVLGLSVAYWLKKLEIRVLVVERDHTYSQASTGLSVGG------------------ICQQFSLPENIQLSLFSASFLRNINEYLAVVDAPPLDLRFNPSGY---LLLASEKDAAAMESNVKVQRQEGAKVSLM------------------------------------------------------------SPDQLRNKFPWINTEGVALASYGMEDEGWCLLQGLRRKVQSLGVLFCQGEVTRFVSSSQRMHEVHVKMDRSLEYQPVECAIVINAAGA----------------------------SAQIAALAGVGEGPPKLPVEPRKRYVYVWHCPQG-------------------PGLETPLVADTSFRREGLGSNYLGGRSP----------TEQEEPDPANLEVDHDFFQDKVWPHLALRVPAFETLKVQSAWAGYYDYNTFDQNG---VVG-----------------PHPLVVNMYFAGFSGH--GLQQAPGIGRAVAEMVLGRFQTIDLSPFLFTRFYLGE.. 478
32 -15.400sp|Q9H9P8|L2HDH_HUMAN L-2-hydroxyglutarate dehydrogenase, mitochondrial OS=Homo sapiens GN=L2HGDH PE=1 SV=3  ali follow..  13  9.........VGACGRARGLFAGGSPGACGFASGRPRPLCGGSRSASTSSFDIVIVGGGIVGLASARALILRSLSIGVLEKEKDLA--VHQTGHNSGVIHSGIYYKPESLKAKL-ALLYEYCQQKGISYKQCG---------------------------KLIVAVEQEEIPRLQALYEKGLQ---------------------------------------NGVPGL--RLIQQEDIKKK----------EPY-----------CRGLMAIDCPHTGYRQVALSFAQDFQEAGGSVLTNFEVKGIEMAKESPSRSIDGMQNTKGEEIRCQYVVTCAGLSDRISELSGCTPDPRIVPFRLLKPEKCYLVKGNIYPVPDSRFPFLGV---HFTPRMDGSIWLGPNAVLAFKREGYRPFDFSATDVMDIIINSGL-----------------------IKLASQNFSYGVTEMYKACFLGATVKYLQKFIPEITI-------------SDILRGPAGVRAQALDRDGNLVEDFVFDAGVGDIGNRLHVRN--APSPAATSSIAISGMIADEVQQR.................... 460
33 -15.100sp|O60341|KDM1A_HUMAN Lysine-specific histone demethylase 1A OS=Homo sapiens GN=KDM1A PE=1 SV=2  ali   12  1.......................................................................GMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLG-GNPMAVVSKQV---NMELAKIKQKCPLYEANGQPKEKDEMVEQEFNRLLEATSYLSHQLDFSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEA--LEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANAT-TVRNGYSCVPVALAE-----GLDIKLNTAVRQVRYTASG......................................................................................................................................................................................................................................................................................... 299
34 -14.500sp|Q16881|TRXR1_HUMAN Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens GN=TXNRD1 PE=1 SV=3  ali   14  2......................................NGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFRWGLGGTC---------VNVGCIPKKLMHQAALLGQALQDSRNYGWKVEE-------------------TVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGI-EYCISSDDLGKTLVVGASYVALE---AGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVTNSEEIIEGEYNTVMLAIGRDACTRKI....................................................................................................................................................................................................................................................... 300
35 -13.900sp|P09622|DLDH_HUMAN Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens GN=DLD PE=1 SV=2  ali follow..  12  34.........................................TYADQPIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTC---------LNVGCIPSKALLNNSHYYHMAHGKDFASRGIEMSEVRLNLDKMMEQKSTA-------VKALTGGIAHLFKQNKVVHVNGYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKID-IEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRGRIPVNTRFQTKIPNIYAIGDVVAGPMLAHK-----AEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGIEYKV-GKFPFAANSRAKTNADTDGMVKILGQKSTDRVLEMVNEAALALEYGASCEDIARPTLSEAFREANLAASFG.......................................................................... 504
36 -13.500sp|O15229|KMO_HUMAN Kynurenine 3-monooxygenase OS=Homo sapiens GN=KMO PE=1 SV=2  ali follow..  10  2..........................................DSSVIQRKKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDT--VATFTRGRSINLALSHRGRQALKAVGLEDQIVSQGIP-----------------------RARMIHSLSGKKSAIPYGTKSQYILSVSR-------------------------------------------------------------------------------------------------------ENLNKDLLTAAEKYNVKMHFNHRLLKC--NPEEGMITVLGSDKVP-KDVTCDLIVGCDGAYSTVRSHLMKKPRFDYSQQYIPHGY--------MELTIPPKNGDYAMEPNYLHIWPRNTF--------------------------------MMIALPNMNKSFTCTLFMPFEEFEKLLT-----------------SNDVVDFFQKYFPDAIPLIGEKLLVQDFF-----LLPAQPMISVKCSSFHFK-------------SHCVLLGDAAHA-GMNAGFEDCLVFDELM--DKFSNDLSLCLPVFSRLRIPD 352
37 -13.400sp|Q8NCN5|PDPR_HUMAN Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial OS=Homo sapiens GN=PDPR PE=1 SV=2  ali   14  7.........................................................................................................................................................................................................................................................ISPKKVAELHHLLNVHDLVGAMHVPEDAVADVALALASAASQNGVQIYDRTSVLHVMVKKG-QVTGVETDKGQ----IECQYFVNCAGQ-----------------WAYELGLSNE--------EPVS-----IPLHACEHFYLLTRPLETPLQS------------------STPTIVDADGRIYIRNWQGGILSGGFEKNPKPIFTEGKNQLEIQNLQEDWDHFEP-LLSSLLRRMPELETLEIMKLVNCPETFTPDMRCIMGES---------------------PAVQGYFVL-AGMNSAGLSFGGGAGKYLAEWMVHGYPSENVWELDLKRFGALQSS 276
38 -13.000sp|Q86VQ6|TRXR3_HUMAN Thioredoxin reductase 3 (Fragment) OS=Homo sapiens GN=TXNRD3 PE=1 SV=3  ali   13  35......................................QKLLQEDLAYDYDLIIIGGGSGGLSCAKEAAILGKKVMVLDFSWGLGGTC---------VNVGCIPKKLMHQAALLGQALCDSRKFGWEYNQ-------------------QVRHNWETMTKAIQNHISSLNWGYRLSLREKAVAYVNSYGEFVEHHKIKATNKKGQETYYTAAQFVIATGERPRYLGI-EYCITSDDLGKTLVVGASYVALE---AGFLAGFGLDVTVMVRSILLRGFDQEMAEKVGSYMEQHGVKFLRKFIPVMVQQLEKGSPGKL.................................................................................................................................................................................................................................................................................... 300
39 -12.900sp|P00390|GSHR_HUMAN Glutathione reductase, mitochondrial OS=Homo sapiens GN=GSR PE=1 SV=2  ali follow..  17  23.......FRGFLLLLPEPAALTRALSRAMACRQEPQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAAELGARAAVVESHK-LGGTC---------VNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWR-------------VIKEKRDAYVSRLNAIYQNTKSHI-EIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELGRSVIVGAGYIAV---EMAGILSAL-TSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLMIPDVDCLLWAIGRVPNTKDL....................................................................................................................................................................................................................................................... 342
40 -12.800sp|Q9UL12|SARDH_HUMAN Sarcosine dehydrogenase, mitochondrial OS=Homo sapiens GN=SARDH PE=1 SV=1  ali   12  6.............................................................................................................................................................................................................................ASNRQRLDEYKRLMSLGKAYGVESHVL--SPAETKTLYPLMNVDDLYGTLYVPHDGPAGTCTTLARAASARGAQVIENCPVTGIRVWTDDRVAGVETQHGS----IQTPCVVNCAGV----------------------------ASAVGRMAGVK-----VPLVAMHHAYVVTERIEGIQN--------------------MPNVRDHDASVYLRLQGDALSV--GGYEANPIFWEEVSDKFAFGLFDLDWEVFTQHIEGAINRVPVLEKTGIKSTVCGPESFTPDHKPLMGEA---------------------PELRGFFLG-CGFNSAGMMLGGGCGQELAHWIIHGRPEKDMHGYD.......... 291
41 -12.400sp|Q9UI17|M2GD_HUMAN(removed signalp:1-23) Dimethylglycine dehydrogenase, mitochondrial OS=Homo sapiens GN=DMGDH PE=1 SV=2  ali   14  2....................................................................................................................................................................................................................................................................LLNMNKVLAGLYNPGDGHYSLTMALAAGARKCGALLKYPAPVTSLKARSD-GTWDVETPQGS----MRANRIVNAAGF---------------AREVGKMIGLEHPLIPVQHQYVVTSTISEVKALKRELPVLRDLEGSYYLRQERDGLLFGPYESQEKMKVQDSWVTNGV-------------------------PGFGKELFESDLDRIME-----HIKAAMEMVPVLKKADIINVVNGPITYSPDILPMVGPH---------------------QGVRNYWVAIGFGY--GIIHAGGVGKYLSDWILHGEPPFDLIELDNRYGKWTTTQ 266
42 -11.700sp|Q9NNW7|TRXR2_HUMAN Thioredoxin reductase 2, mitochondrial OS=Homo sapiens GN=TXNRD2 PE=1 SV=3  ali follow..  12  2...........AAMAVALRGLGGRFRWRTQAVAGGVRGAARGAAAGQRDYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYRWGLGGTC---------VNVGCIPKKLMHQAALLGGLIQDAPNYGWEV---------------AQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSFWLKESPGKTLVVGASYVALE---AGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLRGCAPSRVRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSL-------------NLEKAGVDTSPDTQKILVDSREAT-----SVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPT--------------------FTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVA------------------------GRDASQCYVKMVCLREPPQLVLGLHFLGPNA------GEVTQGFALGIKC....................... 483
43 -11.600sp|Q8NE62|CHDH_HUMAN(removed signalp:1-15) Choline dehydrogenase, mitochondrial OS=Homo sapiens GN=CHDH PE=2 SV=2  ali follow..  11  18.........................................AGSESRDEYSYVVVGAGSAGCVLAGRLTEDPERVLLLE----AGPKDVLAGSKRLSWKIHMPALVANLCDDRYNWCYHTEVQRGLDGRVLYWPRGRVWGGSSSLNAMVYVRGHAEDYERWQRQGARGDYAHCLPYFRKAQGHELGASRYRGADG---------------------LRVSRGKTNHPLHCAFLEATQQAGYPLTEDMNGFQQEGFGWMDMTI------------EGKRWSAACALHPALSRTNLKAEAETLVSRVLFE-GTRAVGVEYVKNGQSHRAYASKVILSGGAINSPQLLIGNADDLKKLGIPVVCHLPGVGQNLQDHLEIYIQQARKVCIGLEWLWKFTGEGATAHLETGGFIRSQPGVPHPDIQFHFLPSQVIDMRGTSVGWLKLRSANPQDHPVIQP-TETDIEDFRLCVKLTREIFAQEALAPFKELQPG-------SHIQSDKEIDAFVRAKADSAYHPSCTCKM-PSDPTAVVDPQTRVLGV--ENLRVVDASIMPSMVSGNLNAPTIMIAEKAADIIKGQPALWDKD... 566
44 -11.400sp|Q16881|TRXR1_HUMAN Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens GN=TXNRD1 PE=1 SV=3  ali   32  137.......................LKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTGLGGTC........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 209
45 -11.300sp|Q12882|DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2  ali   12  30.........................................EKMSEAYSAKIALFGAGPASISCASFLARLGYSITIFEKQEYVGGLSTQFRLPYDVVNFEIELMKDLGVKIICGKSLS---VNEMTLSTLEKGYKAAFIGGLPEPNKDAIFQGLTQDQGFYTSK---------DFLPLVAKGSKA-------------------------------------------GMCACHSPLPSIRGVVIVLGAGDTAFDCATSALRCGARRVFIVFRKGFVNIRAVP-MELAKEEKCEFLPFLSPRKVIVKGG-RIVAMQFETGKQMVHLKADVVISAFGSVLSDPKVKEA.................................................................................................................................................................................................................................................... 300
46 -11.300sp|Q9UJX0|OSGI1_HUMAN Oxidative stress-induced growth inhibitor 1 OS=Homo sapiens GN=OSGIN1 PE=2 SV=2  ali follow..  12  52....AVASRLCVTPGQGCGHQGQDEGPLPAPSPPPAMRKDHLGASSSEPLPVIIVGNGPSGICLSYLLSGYTPYTKPDAIHPHPLLQRK---------------LTEAPGVSILDQDLDYLSEGLEG----------------------RSQSPVALLFDALLRPDTDFGGNMKSVLTWKHRKEHAIPHVVLGRNLPGGAWHSIEGSMVILSQGQWMGLPDLEVKDWMQKKRRGLRNSRA------------------------------------TAGDIAHYYRDYVVKKG-NFVSGAVVTAVEWGTPDSGFLTRNQAQQPFSLWARNVVLATGTFDSPARLGIPGEAELSALEAATRVGAVTPASDPVLIIGAGLSAADAVLYARHY------------NIPVIHAFRRAVDDPGLVFNQLPKMLYPEYHKVHQMMREQSILSPSPYEGYRSLPRHQLLCFKEDCQAVFQDLEGVEKVF------GVSLVLVLIGSHPDLSFLPGAGADFAVDPDQPLSAKRNPIDVDPFTYQSTRQEGLYAMGPLAGDNFVRFVQGGALAVASSLLRKETRKP............... 559
47 -11.300sp|P31040|DHSA_HUMAN(removed signalp:1-19) Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens GN=SDHA PE=1 SV=2  ali   13  39.............................................VDHEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTGGINAALGNME------------------------------------EDNWRWHFYDTVKGSDWL----GDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKFGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYFVEYFALDLLMENGECRGVIALCIE---DGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGT-------AMITRAGLPCQDLEFVQFHPTGIYGAGCLITEG................................................................................................................................................................................................................................................................ 291
48 -11.200sp|Q8TDZ2|MICA1_HUMAN NEDD9-interacting protein with calponin homology and LIM domains OS=Homo sapiens GN=MICAL1 PE=1 SV=2  ali   15  69.................................KRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLGARVVLVEKRTKFS-------------------------------------------------------------------------RHNVLHLWPFTIHDLRA----------------------------------------------LGAKKFYGRFCTGTLDH--------------------------------------SIRQLQLLLLKVALLLGVEIHWGVTFTGLQPPPRKWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGFK...................................................................................................................................................................................................................................................... 228
49 -11.200sp|P31513|FMO3_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 3 OS=Homo sapiens GN=FMO3 PE=1 SV=5  ali follow..  10  2................................................GKKVAIIGAGVSGLASIRSCLEEGLEPTCFEKSNDIGGL--KFSDHAEEGRASIYKSVFSNSSKEMMCFPD-----------------------------FPFPDDFPNFMHN---------SKIQEYIIAFAKEKNLLKYI--------------------------------QFKTFVSSVNKHPDFATTGQWDVTTERDGKKESAVFDAVMVCSGHHVYPNLPK-GLNHFKGKCFHSRDYKEPGVFNGKRV--LVVGLGNSGCDIATE----LSRTAEQVMISSRSGSWVMSRVWDNGYPWDMLLVTRFGTFLKNNLPTAISDWLYVKQMNARFKHENYGLMPLNGVLRKEPVFNDELPASILCGIVSVKPNVKEFTETSAIEDGTIFEGIDCVIFAT-----------------GYSFA---------------YPFLDESIIKSRNNEIILFKGVF-------------------------PPLLEKSTIAVIGFVQSLGAAIPTVLQSRWAAQVIKGTCTLPSMEDMMNDINEKMEKK 416
50 -11.200sp|Q9Y236|OSGI2_HUMAN Oxidative stress-induced growth inhibitor 2 OS=Homo sapiens GN=OSGIN2 PE=2 SV=1  ali follow..  10  2..................................PLVEETSLLEDSSVTFPVVIIGNGPSGICLSYMLS--GYRPYLSSEAIHPNTILNS-ARHLSIVDQDLEYLSEGLEGRS---------------NPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHHYIPHVVLGKGPP----GAWHNMEGSMLTISFGSWMELPGLKFKDWVSSKRRSLKGDRVMPEEIARYYKHYVKVMGLQK-------------------------------------------------------NFRENTYITSVSRLYRDQDDDDIQDRDISTKHLQIEKSNFIKRNWEI--------RGYQRIADGSHVPFCLFAENVALATGTLDSPAHLEIEGEDFPFVFHS---PEFGAAINKGKLRGKVDPVLIVGSGLTAADAVLCAYNSNIP-VIHVFRRRVTDPSLIFKQLPKKLYPEYHKVYHMMCTQSYSVDSNLLSDYTSFPEHRVLSFKSDMKCVLQSVSGLLIGSHPNLSFLKDQGCYLGHKSIKEANLFALGPLVGDNFVRFLKGGALGVTRCLATRQKKKHLFVERGG........ 500
51 -11.100sp|Q99518|FMO2_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 2 OS=Homo sapiens GN=FMO2 PE=1 SV=3  ali follow..  11  2................................................AKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGV--------WRFKENVE-------------------------------------------------DGRASIYQSVVTNTSKEMSCFSDF----------------------------------------------PMPEDFPNFLHNSKLLEYFRIFAKKFDLLKY------------------------------------------IQFQTTVLSVRKCPDFSSSGVVTQSNGKEQSAVFDAVMVCSGHHILPHIPLKSFPGMERFKGQYFHSRQYKHPD-ILVIGMGNSGSDIAV------------------ELSKNAAQVFISTRHGTWVMSRISEDGYPWDSVFHTRFRSMLRNVLPRTAVKWMIEQQMNRWFNHENYGLEPQNKYIMKEPVLNDDVPSRLLCGAIKVKSTVKELTETEDGTV-GYSFSFPFLEDSLVKVENNMVSLSTLACIGLIQPLGSIFPTALQARWVTRVFKGLCSLPSERTMMMDIIKRNEKR 416
52 -11.100sp|O94851|MICA2_HUMAN Protein MICAL-2 OS=Homo sapiens GN=MICAL2 PE=1 SV=1  ali   19  71.................................KRGSHKEYKRGKSCTNTKCLIVGGGPCGLRTAIELAYLGAKVVVVEKRDSFSRNNVLHLWPFTIHDL............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 137
53 -11.000sp|P31512|FMO4_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 4 OS=Homo sapiens GN=FMO4 PE=2 SV=3  ali follow..  9  2................................................AKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDDIGGL--------WKFTESSK-------------------------------------------------DGMTRVYKSLVTNVCKEMSCYSDF----------------------------------------------PFHEDYPNFMNHEKFWDYLQEFAEHFDLLK------------------------------------------YIQFKTTVCSITKRPDFSETGVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFPGIHKFKGQILHSQEYKIPE-VLVIGLGNTGGDIAVELSRT----AAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCCSFIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKKAKFIVNDELPNCILCGAITMKTSVITSAVFEDGTVEENIDVVIFTT-----GYTFSFPFFEEPLKSLCTKKIFLATLAIIGLIGLKGSILSGTLQARWVTRVFKGLCKIPPSQKLMMEATEKEQLI 415
54 -10.900sp|Q7RTP6|MICA3_HUMAN Protein MICAL-3 OS=Homo sapiens GN=MICAL3 PE=1 SV=2  ali   14  71.................................KRGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSGLGAKKFYGKFCAG-AIDHISIRQLQLILLKVALILGIENVEFQGLIQPPEDQENERIGWRALVHPKTHVSEYEFEVIIGGDGRRNTLEGFRR.............................................................................................................................................................................................................................................................................................................................................................................................................................. 234
55 -10.900sp|P49326|FMO5_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 5 OS=Homo sapiens GN=FMO5 PE=2 SV=2  ali follow..  9  2...............................................TKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDDIGG------------------------------LWRFQENPEEGRASIYKSVIINTSKEMMCFSDYPIPDHYPNFMHN---------AQVLEYFRMYAKEFDLLKYI--------------------------------RFKTTVCSVKKQPDFATSGQWEVVTESEGKKEMNVFDGVMVCTGHHTNAHLPL-GIEKFKGQYFHSRDYKNPEGFTGKRV--IIIGIGNSGGDLAVE----ISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRLTHFIWKICGQSLANKYLEKKINQRFDHEMFGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGNVKEFTETAAIEDGSREDDIDAVIFAT-----------------GYSFD---------------FPFLEDSVKVVKNKISLYKKVFP--------------------------PNLERPTLAIIGLIQPLGAIMPISLQGRWATQVFKGLKTLPSQSEMMAEISKAQEE. 415
56 -10.900sp|Q16134|ETFD_HUMAN Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens GN=ETFDH PE=1 SV=2  ali   8  27......................................................................................................................................................................................................................................................................................GHLVSWMGEQAEALGVEVYPGYAAAEVLFHDDGSVKGIATNDFERGLELHAKVTIFAEGCHGHLAKQLYKKFDLRANC----------------------EPQTYGIGLKELWVIDEKNWKPGRVDHTVGWPLDRHTYGGSFLY-----------HLNEGEPLVALGLVVGLD-----------------YQNPYLSPFREFQRWKHH-PSIRPTLEGGKRIA--------ALNEGGFQSIPKLTF----------------PGGLLIGCSPKIKGTHTAMKSGILAAESIFENLQSKTIGLHVTEYEDNLKNS 292
57 -10.800sp|Q12882|DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2  ali   12  180.........................................EKMSEAYSAKIALFGAGPASISCASFLARLGYSITIFEKQEYVGGLST-SEIPQFRLPYDVFEIELMKDLGVKIICGKSLSVNEMTLSTLEKGYKAAFIGGLPEPNKDAIFQGLT.................................................................................................................................................................................................................................................................................................................................................................................................................................................... 298
58 -10.800sp|Q96NN9|AIFM3_HUMAN Apoptosis-inducing factor 3 OS=Homo sapiens GN=AIFM3 PE=1 SV=1  ali   10  38..........................................SAGYSSSTNVLIVGAGAAGLVCAETLRQEGFRIVLCTLDRHL-----PYDRPKLSKSLDTQPEQLALRPKEFFRAYGIEVLTEAQVVTVDV-----------RTKKVVFKDGFKLEYSKLLLAPGSSPKTLSCKGKEVENV-----------------------------------FTIRTPED-ANRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFENNRVKFYMQTEVSELRGQEG-KLKEVVLKSSKV---VRADVCVVGIGAVPATGFL....................................................................................................................................................................................................................................................... 286
59 -10.700sp|Q9Y6N5|SQRD_HUMAN Sulfide:quinone oxidoreductase, mitochondrial OS=Homo sapiens GN=SQRDL PE=1 SV=1  ali follow..  8  4...LVAVVSGPRAQLFACLLRLGTQQVGPLQLHTG------ASHAARNHYEVLVLGGGSGGITMAARMKRKAENVAIVEPSER------------HFYQPIWTLVAGAKQLSSSGRPTASVIPSGVEWIKLNPDKNCIHTDDDEK-RYLIIALGIQLDYEKI----KGLPEGFAHPKIGSNYSVKTVEKTWKALQDFKEGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVK---------------------------KYADALQEIIQERNLTVNYKKNLIEVRADKQEAVFLDKPGETQVISYMSPPDVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNL............................................................................................................................................................................................................................... 340
60 -10.300sp|Q01740|FMO1_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 1 OS=Homo sapiens GN=FMO1 PE=2 SV=3  ali follow..  12  2................................................AKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSDDLGG------------------------------LWRFTEHVEEGRASLYKSVVSNSCKEMSCYSDFPFPEDYPNYVPN---------SQFLEYLKMYANHFDLLKHI--------------------------------QFKTKVCSVTKCSDSAVSGQWEVVTMHEEKQESAIFDAVMVCTGFLTNPYLPL-GINAFKGQYFHSRQYKHPDIFKDKRV--LVIGMGNSGTDIAVE----ASHLAEKVFLSTTGGGWVISRIFDSGYPWDMVFMTRFQNMLRNSLPTPIVTWLMERKINNWLNHANYGL----------------------IPEDRTQLKEFVLNDELPGRIITGKVFI-----------------------------RPSIKEVKENSVIFNNTSKEEPIDIIVFAT----------------GYTFAFPFLDESVVKVEDGQASLPTLAIIGLIKPLGSMIPTGTQARWAVRVLKGVNKLPPPSVMIEEINARKE.. 414
61 -10.000sp|Q9BRQ8|AIFM2_HUMAN Apoptosis-inducing factor 2 OS=Homo sapiens GN=AIFM2 PE=2 SV=1  ali follow..  13  4.........................................QVSVESGALHVVIVGGGFGGIAAASQLQALNVPFMLVDMKDS------------HNVAALRASVETGFAKKTFISYSVTFKDNFRLVVGIDLKNQMVLLQGGEA-SHLILATGSTGPFPGKFNEVSSQQAAIQAYEDMVRQVQRSRFIVVVGGGS-----------------------AGVEMAAEIKTEYPEKEVTLIHSQVALADKELLPS--------------------------VRQEVKEILLRKGVQLLLSERVSNL-LNEYREYIKVQTDKGT---EVATNLVILCTGIK............................................................................................................................................................................................................................................................. 246
62 -9.420sp|P24386|RAE1_HUMAN Rab proteins geranylgeranyltransferase component A 1 OS=Homo sapiens GN=CHM PE=1 SV=3  ali   11  10.....................................................................................................................................................................................................................DEYKGYEEITFYEYLKTQKLTPNLQYIVMHSIAMTSETASSTIDGLKATKNFLHCLGRYFPLYGQGELPQCFCRMCAVFGGIYCLRHSVQCLVVDKESRKCKAIIDQFG--QRIISEHFLVEDSVLITDRSVLKTDSDQQISILTVPAEEPGTFAVRVIELCSSTMTCMKGTYLVHLTCTSSKTAREDLESVVQKLFVPYTEMEIALYFNMRDSSDISRSCYNDLPSNVYVC------------------SGPDCGLGNDNAVKQAETLFQEICP........................................................................................................ 300
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.