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Query: sp|Q8IYK2|CC105_HUMAN Coiled-coil domain-containing protein 105 OS=Homo sapiens GN=CCDC105 PE=2 SV=3, from H.sapiens

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRVLVPPAERSQDTRVGAPAWREAAQAMARTAHILTDRCGQEAVTMWQPKDSVLDPNVAHHLGRAAYIQPWRFRVEMIKGGGTLEKPPPGEGVTLWKGKMKPPAWYARLPLPLHRKARALQTTEVVHAHARGARLTAARLGRAQHQINGRVRQLLRQREVTDHRLSEVRKGLLINQQSVKLRGYRPKSEKVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTLNFCFKERLQAVDLMNQPLDKVLEQARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYNPACALALNEAKRLLVESKDTLVEMAKNEVDVREQQLQISDRVCASLAQKASETLELKERLNMTLGLMRGTILRCTKYNQELYTTHGLIKGPLSKVHLETAEKLDRPLVRMYQRHVGTQLPEAARLAQGTDKLQCHITYLEKNLDELLATHKNLSWGLNCKNIGHEVDGNVVRLRLRQRQPHVCYEQAQRLVKDWDPRTPPPRSKSSADPLast
1 -132.000sp|Q8IYK2|CC105_HUMAN Coiled-coil domain-containing protein 105 OS=Homo sapiens GN=CCDC105 PE=2 SV=3  ali  100  1MRVLVPPAERSQDTRVGAPAWREAAQAMARTAHILTDRCGQEAVTMWQPKDSVLDPNVAHHLGRAAYIQPWRFRVEMIKGGGTLEKPPPGEGVTLWKGKMKPPAWYARLPLPLHRKARALQTTEVVHAHARGARLTAARLGRAQHQINGRVRQLLRQREVTDHRLSEVRKGLLINQQSVKLRGYRPKSEKVPDKADSMLTWEKEELKSMKRKMERDMEKSEVLLKTLASCRDTLNFCFKERLQAVDLMNQPLDKVLEQARRHSWVNLSRAPTPRTQGQKTPPPDPVGTYNPACALALNEAKRLLVESKDTLVEMAKNEVDVREQQLQISDRVCASLAQKASETLELKERLNMTLGLMRGTILRCTKYNQELYTTHGLIKGPLSKVHLETAEKLDRPLVRMYQRHVGTQLPEAARLAQGTDKLQCHITYLEKNLDELLATHKNLSWGLNCKNIGHEVDGNVVRLRLRQRQPHVCYEQAQRLVKDWDPRTPPPRSKSSADP 499
2 -69.300sp|Q969V4|TEKT1_HUMAN Tektin-1 OS=Homo sapiens GN=TEKT1 PE=2 SV=1  ali follow..  13  1MAKLLQPPP-----KFLPSEWHIANKNQYHRADA----------------------------------------------------------QRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKLEQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKALETLKEPLHITETCLAYREKRIGIDLVHDTVEHELIKEAEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDICFSLNNNSPNIRYSENAVRIE---------PNSVSLEDWLDFSSTNVEKADKQRNNSLMLKALVDRILSQTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQEGPAKVAHTRLETRTHRPNVELCRDVAQYRLKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEIQVKENTIYIDEVLCMQMRKSIPLR............................ 400
3 -68.100sp|Q8WW24|TEKT4_HUMAN Tektin-4 OS=Homo sapiens GN=TEKT4 PE=2 SV=1  ali follow..  12  27.....................................................SGLATASFRTSKYLLEEWFQN--------CYARYHQAFADRDQSERQRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLLAQKQRLERALDATEVPFSITTDNLQCRERREHPNLVRDHVETELLKEAELIRNIQELLKRTIMQAVSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQ---------ESASTPETRAKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELEDARYKLHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDAAQFRLSEVEELNMSLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFID------RQKCMAHRTRYPTILQLAGY................ 434
4 -67.700sp|Q9UIF3|TEKT2_HUMAN Tektin-2 OS=Homo sapiens GN=TEKT2 PE=1 SV=1  ali follow..  11  2.......................................................ATLSVKPSRRFQLPDWHTN--------SYLLSTNAQLQRDASHQIRQEARVLRNETNNQTIWDEHDNRTRLVERIDTVNRWKEMLDKCLTDLDAEIDALTQMKESAEQNLQAKNLPLDVAIECLTLRESRRDIDVVKDPVEDELHKEVEVIEATKKALQQKVSQAFEQLCLLQEVQQQLNSDHRGKMETLEIDRGCLSLNLRSPNISLKVDPTRVP---------DGSTTLQQWDDFSRFNKDRAEAEMKAATELREATALTIAETNNELEAQRVATEFAFRKRLREMEKVYSELKWQEKNTLEEIAELQEDIRHLEEDLRTKLLSLKLSHTRLEARTYRPNVELCRDQAQYGLDEVHQLEATIAALKQKLAQAQDALDALCKHLARLQADIACKANSMLLDTKCMDTRRKLTVPAERFTRTTNSTLSPLKSCQLELA...... 430
5 -61.700sp|Q96M29|TEKT5_HUMAN Tektin-5 OS=Homo sapiens GN=TEKT5 PE=2 SV=1  ali follow..  12  79.......................................................PTLRSALFSRYSPHDWDQS--------NQLQVRGAEASRLWASRLTDDSMRLLQDKDQLTHQMQEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRLECAANEVNCPLQVALECLYHREKRIGIDLVHDNVEKNLIREVDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLEDKSSAQCIDEKCFNLRNTSDCISFFHGMEKID---------GTISVPETWAKFSNDNIKHSQNMRANSIQLREEAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLERSIMAKEGPLKVAQTRLECRTRRPNMELCRDIPQLKLNEVFTIDDTLQTLKLRLRETQDTLQLLVMTKCRLEHELAIKANTLCIDKEKCMGMRKT------FPCTPRLVGH................ 484
6 -56.300sp|Q9BXF9|TEKT3_HUMAN Tektin-3 OS=Homo sapiens GN=TEKT3 PE=1 SV=1  ali follow..  12  95..........................................................................TPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEAQLLTEVDTILCCQERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERVD---------ATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIELCRDMAQLRLNEVHEVDDTIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYID------QEKCMSMRKSYPNTLRLVGF................ 489
7 -32.100sp|Q8NAE5|TKT4M_HUMAN Tektin-4 like protein LOC389833 OS=Homo sapiens PE=2 SV=2  ali follow..  15  21........................................................................................................................................................................................................................................................................................RSASTPETRTKFTQDNLCHAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGCRCEELEDARHKLQHHLHKMLREITDQEHNVVALKEAIKDKEEPLHIAQTRLYLLSHRPNMQLCREAAQFRYCL........................................................................................ 151
8 -29.600sp|Q8WZ33|MAFIP_HUMAN MaFF-interacting protein OS=Homo sapiens GN=MAFIP PE=1 SV=1  ali follow..  16  3...........................................................................................................................................................................................................................................................................................................................................................................CPRAAFLVGSFHGVFPGPPASSHWEFWVPSTPVGAYFCPPQPQLTPSEVEELYKSITALREKLLQAEQSLRNLKDIHMSLEKDVTAMTNSVFID------RQKCMAHRTCYPTILQLAGY................ 123
9 -13.300sp|Q07065|CKAP4_HUMAN Cytoskeleton-associated protein 4 OS=Homo sapiens GN=CKAP4 PE=1 SV=2  ali   8  1.............................................................................................................................LGQGLQGVEQKVQSLQATFGTFESILRSSQHKQDLTEKAVKQGESEVSRISEVLQ-KLQNEILKDLSDGIHVVKDARERDFTSLENTVEERLTELTKSINDNIAIFTEVQKRSQKEINDMKAKVASLEESEGNKQ---------------------DLKALKEAVKEIQTSAKSREWDMEALRSTLQTMESDIYTEVRELVSLKQEQQA-FKEAADTERLALQALTEKLLRSEESVSRLPEEIRRLEEELRQLKSDSHGPKEDGGFRHSE-AFEALQQKSQGLDSRLQHVEDGVLSMQVASARQTESLESLLSKSQEHEQRLA................................................... 299
10 -13.300sp|Q16363|LAMA4_HUMAN(removed signalp:1-27) Laminin subunit alpha-4 OS=Homo sapiens GN=LAMA4 PE=1 SV=4  ali   12  16...........................................................................................................................DQALNYVRDAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLS-----------------ELDDIIKNASGIYAEIDGAKSELQVKLSNLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDM--------------NGLVQKALDASNVYE-NIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAER-----------GDAQQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNT................................................. 299
11 -12.600sp|Q5TZA2|CROCC_HUMAN Rootletin OS=Homo sapiens GN=CROCC PE=1 SV=1  ali   10  4........................................................................................................................................PEAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSR-----------RQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQ-------------SKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDK--NLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVAD.................................................. 300
12 -12.400sp|Q8IUD2|RB6I2_HUMAN ELKS/Rab6-interacting/CAST family member 1 OS=Homo sapiens GN=ERC1 PE=1 SV=1  ali   11  5...........................................................................................................................EELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQR-----------AILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIE-------------------------------NLQEQLRDKEKQMSSLKERVKSLQADTTNTDTAL----TTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEH--ASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKD.................................. 299
13 -12.200sp|Q14BN4|SLMAP_HUMAN Sarcolemmal membrane-associated protein OS=Homo sapiens GN=SLMAP PE=1 SV=1  ali   7  1........................................................................................................................................LSPSKEKSSDDTTDAQMDEQDLNEPLAKVSLLKDDLQGAQSEIEAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQVEESTKQIQVLQAQLQRLHIDTEKDSEITSTRDELLSARDEILLLHQAAAKVASERDTDIASLQEELKKVRAELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHSLKRENVLLSSELQRQEKELHNSQKQSLELTSDLSI------------------MSRKELENQVGSLKEQHLRDSADLKTLLSKAENQAKDV.................................................... 300
14 -11.900sp|Q9BZW7|TSG10_HUMAN Testis-specific gene 10 protein OS=Homo sapiens GN=TSGA10 PE=1 SV=1  ali   9  1.................................................................................................................................VHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELRQKAENNSLRLLYENTEKDLSDTQRHLAKKKYELQLTQEKIDEKIDNFTRQNIAQREEISILGGTLNDLAKEKECLQACLD------------------------KKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQCTEALIVCEQDVSRMRRQLD-ETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLE--VNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELITAE................................................ 299
15 -11.800sp|Q9Y6C2|EMIL1_HUMAN(removed signalp:1-23) EMILIN-1 OS=Homo sapiens GN=EMILIN1 PE=1 SV=2  ali   9  1..........................................................................................................AMQACGQLCSGAPGEQDSQVSEILSALERRVLDSEGQLRLVGSGLHTVEAAGEARQATLEGLQEVVGRLQDRVD------AQDETAAEFTLRLNLTAARLGQLEGLLQAHGDEGCGACGGVQEELGRLRDGVERCSCPLL--------------------------------PPRGPGAGPGVGGPSRGPLDGFSVFGGSSGSALQALQGELSEVILSFSSLNDSLN-ELQTTVEGQGADLADLGATKDRIISEINRLQQEATEHATESEERFRGLEEGQAQAGQ-----------PSLEGRLGRLEGVCERLDTVAGGLQGLREGLSRLWAGLRETNTTSQMQA................................................ 300
16 -11.700sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus protein 1 OS=Homo sapiens GN=NUMA1 PE=1 SV=2  ali   9  3...........................................................................................................................STLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMLERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARA---------------------------ELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVK-QLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERS--LEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ................................................... 300
17 -11.700sp|Q5KU26|COL12_HUMAN Collectin-12 OS=Homo sapiens GN=COLEC12 PE=1 SV=3  ali   9  1...........................................................................................................................SQLKETLENNSFLITTVNKTLQAYNGYVTNLQQDTSVLQGNLQNQMYSHNVVIMNLN-----------------NLNLTQVQQRNLITNLQRSVDDTSQAIQRIKNDFQNLQQVFLQAKKDTDWLKEKVQSLQTLAANNS----------------------------------ALAKANNDTLEDMNSQLNS-FTGQMENITTISQANEQNLKDLQDLHKDAENRTAIKFNQLEERFQLFETDIVNIISNISYTAHHLRTLTSNLNEVRTT--------------DTLTKHTDDLTSLNNTLANIRLDSVSLRMQQDLMRSRL--DTEVANLSVIMEEMKLVDSKHGQLIKNFTILQG................. 293
18 -11.600sp|Q08378|GOGA3_HUMAN Golgin subfamily A member 3 OS=Homo sapiens GN=GOLGA3 PE=1 SV=2  ali   6  1..........................................................................................................................................AQVECSHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNAS-----------ASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKA------------------QAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERER--LQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLD............................................ 291
19 -11.500sp|P06753|TPM3_HUMAN Tropomyosin alpha-3 chain OS=Homo sapiens GN=TPM3 PE=1 SV=1  ali follow..  10  3..........................................................................................................................................AIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKK-------KGTEDELDKYSEALKDAQEKLEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADES-----------------ERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKL--------VIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDK--LKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMT................................................... 282
20 -11.500sp|Q9BZW7|TSG10_HUMAN Testis-specific gene 10 protein OS=Homo sapiens GN=TSGA10 PE=1 SV=1  ali   8  1.............................................................................................................................MKNIIAEMEQASRQCTEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDND-----------------NLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNKLKNILKSEESENRQMMEQLRKA-----------------NEDAENWENKARQSEADNNTLKLELITAEAEGNRLKEKVDSLNREVEQHLNAERSTLHKSVVKMEEELQKVQFEKVSALADLSSTRELCIKLDSSKELLNRQLVAKDQEIEMRENE--LDSAHSEIELLRSQMANERISMQNLEALLVANRDKEYQSQIALQEKESEIQLLKEHLC............................................ 300
21 -11.500sp|Q8N283|ANR35_HUMAN Ankyrin repeat domain-containing protein 35 OS=Homo sapiens GN=ANKRD35 PE=2 SV=2  ali   9  3........................................................................................................................................KALGGLAKGQLEKEMSVLRLSNSNLLEELGELGRERQRLQRELQSLSQRLQR----------EFVPKPEAQVQLQQLRQSVGLLTNELAMEKEATEKLRKLLASQSSGLCLPADLVGERSAQSKAAESLEELRACISTLVDRHREAQQVLARLQEENQQLRGSLSPCREPGTSLKAPASPQVAALEQDLGKLEEELR-AVQATMSGKSQEIGKLKQLLYQATEEVAELRAREAASLRQHEKTRGSLVAQAQAWGQELKA--------------EKYNTACREVGRLREAVAEERRRSGDLAAQAAEQERQASEMR................................................ 299
22 -11.400sp|P46939|UTRO_HUMAN Utrophin OS=Homo sapiens GN=UTRN PE=1 SV=2  ali   7  9...............................................................................................................................................VEEINKTVSRMKITKADLEQRHPQLDYVFTLAQNLKNKASSSDMRTAITEKLER-VKNQWDGTQHGVELRQQQLEDMIIDSLQWDDHREETEELMRKYEARLY-------------------------------------ILQQARRDPLTKQISDNQILLQELGPGDGIVMAFDNVLQKLLEEYGSDDTRNVKETTEYLKTSWINLKQSIADRQNALEAEWRTVQASRRDLENFLKWIQEAETTVNVLVD-------RENALQDSILARELKQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALGNSEEATMLQHRLDDMNQR................................. 289
23 -11.300sp|O15083|ERC2_HUMAN ERC protein 2 OS=Homo sapiens GN=ERC2 PE=1 SV=3  ali   9  2............................................................................................................................ALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ-----------QDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNT------DTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLID-LKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFA-----------------DQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIA............................................ 298
24 -11.200sp|Q9BXX0|EMIL2_HUMAN(removed signalp:1-30) EMILIN-2 OS=Homo sapiens GN=EMILIN2 PE=1 SV=3  ali   9  1...........................................................................................................................GEVGDLKQLVDQKIQSLEDRLGSVLLQMERVMMELNHLKDKVQVVEDICLLNIQGKPHGMEGALPNREDRAVRHLLKSLNDTMHRKFQETEQTIQKLQQDFSFLYSQLNHTENDVTHLQKEMSNCRAGENAGMGRFTKV-----------------GEQERTVDTLPSPQHPVAHCCSQLEERWQRLQSQVISELDACKECTQGVQREVS-MVEGRVSHMEKTCSKLDSISGNLQRIKEGLNKHVSSLWNCVRQMNGTLRSHS-----------------------RDISGLKNSVQQFYSHVFQISTDLQDL............................................................... 299
25 -11.200sp|P09493|TPM1_HUMAN Tropomyosin alpha-1 chain OS=Homo sapiens GN=TPM1 PE=1 SV=2  ali follow..  8  2...........................................................................................................................DAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEA-DAQEKLELAEKKATDAEADVASLNRRIEEELDRAQERLATALQKLEEAEKAADESERGMK---------------------------------------------VIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVI-IESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDK--LKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTS.................................................. 283
26 -11.200sp|Q02224|CENPE_HUMAN Centromere-associated protein E OS=Homo sapiens GN=CENPE PE=1 SV=2  ali   7  14...........................................................................................................................LESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSE--------------------------------LKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQG-LLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVN---------LSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD................................................ 300
27 -11.100sp|Q5TZA2|CROCC_HUMAN Rootletin OS=Homo sapiens GN=CROCC PE=1 SV=1  ali   12  1....................................................................................................................................LSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRRLEEEQEDAVQDGARVRRELERSHRQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVAR-----QGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVE----------------ALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEAT................................................... 300
28 -11.000sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus protein 1 OS=Homo sapiens GN=NUMA1 PE=1 SV=2  ali   12  30................................................................................................................................RFLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRD-----------------ELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQ--------AQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVL-----------------------QLETLKQEAATLAANNTQLQARVEMLETERGQQEAKL.................................................... 300
29 -11.000sp|Q03001|DYST_HUMAN Dystonin OS=Homo sapiens GN=DST PE=1 SV=4  ali   9  1.................................................................................................................................LESLLSWMVDTEELVANQKKVVKAQIQEQKLLQRLLDDRKSTVVIKREGEKIATTAEPADK------VKILKQLSLLDSRWEALLNKAETRNRQLEGISVVAQQFHETLEPLNEWLTTIEKRL----------------------------VNCEPIGTQASKLEEQIAQHKALEDDIINHNKHLHQAVSIGQSLKVLSSREDKDMVQSKLDFSQVWYIEIQEKSHSRSELLQQALCNAKIFGEDEVELMNWLNEVHDKLSK----------LSVQDYSTEGLWKQQSELRVLQEDILLRKQNVDQALLNGLELLKQTTGDEVL-IIQDKLEAIKAR................................. 299
30 -11.000sp|Q9NT22|EMIL3_HUMAN(removed signalp:1-22) EMILIN-3 OS=Homo sapiens GN=EMILIN3 PE=2 SV=2  ali   10  1...................................................................................................................................RVQSLEERLATLAGELSHDSASPGRSAPLVQTELAVLEQRLVSLETSCTPSTTSAILD--------SLVAEVKAWQSRSEALLRQVASHAALLQQLNGTVAEVQGQLAE-GTGSSLQGEITLLKVNLNSVSKSLTGLSDSVSQYSDAFLAANTSLDERERKVEAEVQAIQEQVSSQGSRLQAGHRQVLNLRGELEQLKAGVAK-VASGLSRCQDTAQKLQHTVGHFDQRVAQVEGACRRLGLLAAGLDSLPTEPL-----------------------RPREGLWSHVDQLNRTLAQHTQDIARLRDDLLDCQAQLAEQVRPGQAN.......................................... 294
31 -10.900sp|Q8NF91|SYNE1_HUMAN Nesprin-1 OS=Homo sapiens GN=SYNE1 PE=1 SV=3  ali   8  1...........................................................................................................................RLMEQKFQQVDEWLKTAEEKVSPRTRRQSNRATKEIQLHQ-MKKWHEEVTAYRDEVEEVGARAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESESSLSSYSDWYGSTHKNFKNVATKIDKVD--------------------------TVMMGKKLKTLEVLLKDMEKGHSLLKSAREKGERAVKYLEEGEAERLRKEIHDHMEQLKELTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIAEYQEILHV----------PEEPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKDKIDQ......................................... 298
32 -10.900sp|Q5TZA2|CROCC_HUMAN Rootletin OS=Homo sapiens GN=CROCC PE=1 SV=1  ali   9  2...........................................................................................................................VKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVE-----------------RLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVL------------------------QERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQ-RQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVA---RRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHPAQLEVDAQQQ.................................. 300
33 -10.900sp|Q14789|GOGB1_HUMAN Golgin subfamily B member 1 OS=Homo sapiens GN=GOLGB1 PE=1 SV=2  ali   10  16.......................................................................................................................ENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLK--------VKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKKELKHLHHDAGIMRNETETA------------------EERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELD-ELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDE----------------QLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWN...................................................... 300
34 -10.900sp|P35749|MYH11_HUMAN Myosin-11 OS=Homo sapiens GN=MYH11 PE=1 SV=3  ali   9  1........................................................................................................................ELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA-----------QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLA-------------------------------EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIAD-LQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA--RNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETR--SHEAQVQEMRQK................................. 300
35 -10.900sp|Q9UPN3|MACF1_HUMAN Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 OS=Homo sapiens GN=MACF1 PE=1 SV=3  ali   8  1........................................................................................................................QARQLATKFQSTYEELTGWLREVEEELAEQIPQFQQRQKELKKEVMEHRDTVNEVSRALLELVPWRAREGLDKLVSD-ANEQYKLVSDTIGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLM-----------------------------------ALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFGTCGEEQKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQ----------LPSPAIDHEQLRQQQEEMRQLRESIAEHKPHIDKLLKIGPQLKELNPEEGEMV............................................. 300
36 -10.800sp|Q8NF91|SYNE1_HUMAN Nesprin-1 OS=Homo sapiens GN=SYNE1 PE=1 SV=3  ali   10  1..........................................................................................................................................KLHQLQMPSRHAISEVMSWISLMENVIQKDEDN-AIHEYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTEKIQLLEGLLESWS--------------------------ENNVQCLKTWFETQEKRLKSVQNALKDCQDLEDLIEKIEQNGLALIQNKKEDVSSIVMSTLRELGQTWANLDHMVGQLKILLKSVLDQWSSHKVAFDKINSYLMEARYSLSR----------FRLLTGSLEAVQVQVDNLQNLQDDLEKQERSLQKFGSITNQLLKE..................................................... 300
37 -10.800sp|Q07065|CKAP4_HUMAN Cytoskeleton-associated protein 4 OS=Homo sapiens GN=CKAP4 PE=1 SV=2  ali   8  1....................................................................................................................KSREWDMEALRSTLQTMESDIYTEVRELVSLKQEQQAFKEAADTERLALQALTEKLLRSEESVSIRRLEEELRQLKSDSHGPKEDGGFRHSEAFEALQQKSQGLDSRLQHVEDGVLSMQVASARQTESLESLLSKSQEHEQRLAALQGRLEGLGSSEADQDGLASTVRSLGETQLVLYGDVEELKRSVGELPSTVESLQKVQEQVHTLLSQDQAQAARLPPQDFLDRLSSLDNLKASVSQVEADLKMLRTAVDSLV-------------------------------------AYSVKIETNENNLESAKGLLDDLRNDLDRLFVKVEK...................................................... 297
38 -10.800sp|Q13751|LAMB3_HUMAN(removed signalp:1-17) Laminin subunit beta-3 OS=Homo sapiens GN=LAMB3 PE=1 SV=1  ali   11  9.............................................................................................................................................ATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARR---------------------LQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLR---------------------------------------------LIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEE--------LRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQSSMEQGARIQKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRDHINGR................................................. 247
39 -10.800sp|Q15075|EEA1_HUMAN Early endosome antigen 1 OS=Homo sapiens GN=EEA1 PE=1 SV=2  ali   7  2.................................................................................................................................VQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQR------ADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDL-QKKSEALESIKQKLTKQEEEKKILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKD----------------KLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQ................................................. 300
40 -10.800sp|Q7Z7A1|CE110_HUMAN Centriolin OS=Homo sapiens GN=CEP110 PE=1 SV=2  ali   13  1.............................................................................................................................LQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERN-HHLQVLKESEVLLQAKRAELEKLKSQVQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQ----------------------------------EALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKE-EENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLE--LENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCD............................................ 297
41 -10.700sp|A6NC98|CC88B_HUMAN Coiled-coil domain-containing protein 88B OS=Homo sapiens GN=CCDC88B PE=1 SV=1  ali   10  6...........................................................................................................................EAQNTEAARLSKELAQARRAEAEAHREAEAQAWEQARLREAVEAAGQELESASQEREALVEA-----------AAAGRERRQWEREGSRLRAQSEAAEERMQVLESEGRQHLEEAERERREKEALQAELEKAVVRGK-------------------------------ELGDRLEHLQRELEQAALERQEFLREKESQHQRYQGLEQRLEAELQAAATSKEEALMELKTRALQLEEELFQLRQGPAGLGPKKRAEPQLVETQNVRLIEVERS--KAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSVLEIQGQELHRKL............................................. 300
42 -10.700sp|Q15075|EEA1_HUMAN Early endosome antigen 1 OS=Homo sapiens GN=EEA1 PE=1 SV=2  ali   11  1.............................................................................................................................LQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFK--------------------------------------QLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIG-NQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAE---------IEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLK............................................ 283
43 -10.700sp|Q96PK2|MACF4_HUMAN Microtubule-actin cross-linking factor 1, isoform 4 OS=Homo sapiens GN=MACF1 PE=1 SV=2  ali   10  3...........................................................................................................................REFQESFKNIEKKVEGAKHQLEISNKNLEKLRAQQEVLQALEPQVDYLRNFTQGLVEDAPDGSDASQLLHQAEV-AQQEFLEVKQRVNSGCVMMENKLEGIGQFHCRVREMFSQLADLDDELD-----------------------------------GMGAIGRDTDSLQSQIEDVRLFLNKIHVLKLDIEASEAECRHMLEEEGTLDLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYRKLKGLNDATTAAEEAEAL----------QWVVGTEVEIINQQLADFKMFKEQVDPLQMKLQQVNGLGQGLIQSAGKDCDVQGLE.......................................... 300
44 -10.700sp|P11532|DMD_HUMAN Dystrophin OS=Homo sapiens GN=DMD PE=1 SV=3  ali   13  1...........................................................................................................................RKIQNHIQTLKKWMAEVDVFLKEEWEILKKQLKQCRLLVSDIQTIQPSLSVNEGGQKIKNEAEPEFA------SRLETELKELNTQWDHMCQQVYARKEALKGGLEKTVSLQKDLSEMHEWMTQAEEEY----------------------------LERDFEYKTPDELQKAVEEMKRAKEEAQQKEAKVKLLTESVNSVIAQAPPVAQEALKKELETLTTNYQWLCTRLNGKCKTLEEVWACWHELLSYLEKANKWLNEVEFKLKTTENIPG-----EEISEVLDSLENLMRHSEDNPNQIRILAQTLTDGGVMDELINEELET.................................................. 296
45 -10.600sp|Q03001|DYST_HUMAN Dystonin OS=Homo sapiens GN=DST PE=1 SV=4  ali   9  1.............................................................................................................................................ETVKQQIEELKQFKSEAYQQQIEMERLNH---QAELLLKKVTEESDKHTVQDPLME-LKLIWDSLEERIINRQHKLEGALLALGQFQHALDELLAWLTHTEGLLS-----------------------------------EQKPVGGDPKAIEIELAKHHVLQNDVLAHQSTVEAVNKAGNDLIESSAGEEASNLQNKLEVLNQRWQNVLEKTEQRKQQLDGALRQAKGFHGEIEDLQQWLTDTERHLLA----------SKPLGGLPETAKEQLNVHMEVCAAFEAKEETYKSLMQKGQQMLARCPKSAET-NIDQDINNLKEK................................. 275
46 -10.600sp|P35609|ACTN2_HUMAN Alpha-actinin-2 OS=Homo sapiens GN=ACTN2 PE=1 SV=1  ali   10  7..................................................................................................................................RTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGA-----QRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHETWAYGKEQILLQ-----------------------------------KDYESASLTEVRALLRKHEAFESDLAEQIAAIAQELNELDYHDAVNVNDRCQKICDQWDRLGTLTQKRREALERMEKLLETIDQLHLEFAKRAAPFNNWMEGAME----DLQDMFIVHSIEEIQSLITAHEQFKATLPEADGERQSIMAIQNEVEKVIQSYNIRIS............................................ 294
47 -10.600sp|Q8NF91|SYNE1_HUMAN Nesprin-1 OS=Homo sapiens GN=SYNE1 PE=1 SV=3  ali   8  1...............................................................................................................................SRFQELMEWAEEQQPNIAEALKQSPPPDMAQNLLMD-HLAICSELEAKQMLLKIKDADRVMADLGLNERQVIQKALSDAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKI----------------------------MFREHICLLPDDVSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQKCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFP----------EINLMNESSELHTQLAKYQNILEQSPEYENLLLTLQRTGQTILPSLNEVDHS-YLSEKLNALPR.................................. 300
48 -10.600sp|P0CAP1|GCOM1_HUMAN GRINL1A complex locus protein 1 OS=Homo sapiens GN=GCOM1 PE=2 SV=1  ali follow..  11  93.........................................................................................................................STSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDR---FNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRVAQVENQLLKMKVESSQE------------------------------------ANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLESFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQ------EASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKLQQK------QLLILQLLEK................................. 394
49 -10.600sp|P24043|LAMA2_HUMAN(removed signalp:1-22) Laminin subunit alpha-2 OS=Homo sapiens GN=LAMA2 PE=1 SV=4  ali   12  3..........................................................................................................................KRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQ-LNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGL---------------------KEDAKGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENDTLGKLSAIPNDTAAKLQAVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADA-------TVKNLEQEADRLIDKLKPIKELEDN................................................................ 300
50 -10.600sp|Q5TZA2|CROCC_HUMAN Rootletin OS=Homo sapiens GN=CROCC PE=1 SV=1  ali   13  1...........................................................................................................................................LRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQK----ALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELA---------------------------------------------ELQGRLALGERAEKESRRETLGLRQRLLKGEASLEVMRQEL-QVAQRKLQEQEG-ERRLLGSLEEARGTEKQQLDHARGLELKLEAARAEAAELGLRLSAAEGR----------------AQGLEAELARVEVQRRAAEAQLGGLRSALRRG........................................................ 243
51 -10.600sp|P12814|ACTN1_HUMAN Alpha-actinin-1 OS=Homo sapiens GN=ACTN1 PE=1 SV=2  ali   8  4..................................................................................................................................NTMHAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGC-LEQVEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLR-------------------------------------------KDYETATLSEIKALLKKHEAFESDLAEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAME----DLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVN.............................................. 285
52 -10.500sp|Q15075|EEA1_HUMAN Early endosome antigen 1 OS=Homo sapiens GN=EEA1 PE=1 SV=2  ali   11  1.......................................................................................................................TQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLH-------------RIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQRE---EKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQS-TTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGE-------------TAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLH................................................... 299
53 -10.500sp|Q8NF91|SYNE1_HUMAN Nesprin-1 OS=Homo sapiens GN=SYNE1 PE=1 SV=3  ali   10  1..........................................................................................................................RDVIEDTLGCLLGRLSLLDSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADNKYIILQKLANVFEQPVAEQIEDGLKEFDAGIIELKRRGDKLQVESMQELSKLQDMYDELMMIIGSRRSGLN------------------------QNLTLKSQYERALQDLADLLETGQEKMEEIQQLLDKHKEYFQGLESHMILTETLFRKIISFAVQKETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDQQELSRQLEVVESSIPS----------VGLVEENEDRLIDRITLYQHLKSSLNEYQPKLYQV............................................................... 299
54 -10.500sp|Q8NF91|SYNE1_HUMAN Nesprin-1 OS=Homo sapiens GN=SYNE1 PE=1 SV=3  ali   12  1............................................................................................................................TVVRYLFQTGSSHERSFSSLESLSSELEQTKEFSKRTESIAVQAEN---LVKEASEIPLGPQNKQLLQQQAKS-IKEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKEKELN--------------------------------------ALETSSSAMDMQISQIKVTIQEIESKLSSIVGLEEEAQSFAQFVTTGESARIKAKLTQIRRYGEELREHAQCLEGTILGHLSQQQKFEENLRKIQQSVSEFEDKLAV----------PIKICSSATETYKVLQEHMDLCQALESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKE.............................. 295
55 -10.500sp|P11277|SPTB1_HUMAN Spectrin beta chain, erythrocyte OS=Homo sapiens GN=SPTB PE=1 SV=5  ali   10  1..........................................................................................................................EKMIEKYSGLASDLLTWIEQTITVLNSRVQQQLQAFSTYRTVEKPPKFQEFTIQSRMRANNQKVYTPHDGKLVSD-INRAWESLEEAEYRRELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVA------------------------------------QDNFGYDLAAVEAAKKKHEAIETDTARALEDLAQELEKENYHDQKRITARKDNILRLWSYLQELLQSRRQRLETTLALQKLFQDM------------LHSIDWMDEIKAHLLSAEFGKHLLEVEDLLQKHKLMEADIAIQGDKVKAITAATLKFTEG..................................................... 297
56 -10.500sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus protein 1 OS=Homo sapiens GN=NUMA1 PE=1 SV=2  ali   12  2...........................................................................................................................................LKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQELEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLE------------------------TLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQ-----LAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATA............................................. 288
57 -10.500sp|P35579|MYH9_HUMAN Myosin-9 OS=Homo sapiens GN=MYH9 PE=1 SV=4  ali   11  4...........................................................................................................................ARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMIT---------------------------------------------DLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAE-LKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQ--LEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEE.......................................... 300
58 -10.500sp|O43707|ACTN4_HUMAN Alpha-actinin-4 OS=Homo sapiens GN=ACTN4 PE=1 SV=2  ali   9  3...........................................................................................................................SDLLEWIRRTIPWLEDPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLK------------------------------------RDYETATLSDIKALIRKHEAFESDLAEQIAAIAQELNELDYYDSHNVNTRCQKICDQWDALGSLTHSRREALEKTEKQLEAIDQLHLEYAKRAAPFNNWMESAMED----LQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQR...................................................... 296
59 -10.400sp|Q08043|ACTN3_HUMAN Alpha-actinin-3 OS=Homo sapiens GN=ACTN3 PE=1 SV=2  ali   6  18..................................................................................................................................PSMSAMQRKLEDFRDYRRLHKPPRIQEKCQLEINFNTLQTKLRLSHRPAFMPSEGKLVSDIANAWRG-LEQVEKGYEDWLLSEIRRLQRLQHLAEKFRQKASLHEAWTRGKEEMLS-------------------------------------------RDYDSALLQEVRALLRRHEAFESDLAEHIAALAQELNELDYHEAASVNSRCQAICDQWDNLGTLTQKRRDALERMEKLLETIDRLQLEFARRAAPFNNWLDGAVE----DLQDVWLVHSVEETQSLLTAHDQFKATLPEADRERGAIMGIQGEIQKICQTYGLR.............................................. 299
60 -10.400sp|Q8NF91|SYNE1_HUMAN Nesprin-1 OS=Homo sapiens GN=SYNE1 PE=1 SV=3  ali   9  5.............................................................................................................................................ASVQNALKDCQDLEDLIKAKEKEVEKIE------------QNGLALIQNKKEDVSSIVMSTLRELGQTWANLDHMVGQLKILLKSVLDQWSSHKVAFDKINSYLMEARYSL----------------------------SRFRLLTGSLEAVQVQVDNLQNLQDDLEKQERSLQKFGSITNQLLKECHPPVTETLTNTLKEVNMRWNNLLEEIAEQLQSSKALLQLWQRYKDYSKQCASTVQQQEDRTNE------LLKAATNKDIADDEVATWIQDCNDLLKGLGTVKDSLFFLHELGEQLKQQVD-ASAASAIQSDQLSLSQH................................. 282
61 -10.400sp|Q9NRC6|SPTN5_HUMAN Spectrin beta chain, brain 4 OS=Homo sapiens GN=SPTBN5 PE=1 SV=1  ali   14  2.......................................................................................................................QETELLQTQYEQLVADLLRWIAEKQMQLEARMRQLLAAFTIFRTQEKPAEALLFRLQTALQAQNRRPFLPHEGLGLAE-LSQCWAGLEWAEAARSQALQQRLLQLQRLETLARRFQRKAALRESFLKDAEQVLD------------------------------------ARAPPASLATVEAAVQRLGMLEAGILQALAEIADILRQEQYHSWADVARRQEEVTVRWQRLLQHLQGQRKQVADMQAVLSLLQEV------------EAASHQLEELQEPARSTACGQQLAEVVELLQRHDLLEAQVSAHGAHVSHLAQQTAELD....................................................... 300
62 -10.400sp|Q9UPN3|MACF1_HUMAN Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 OS=Homo sapiens GN=MACF1 PE=1 SV=3  ali   11  1....................................................................................................................................................QQVQFMLKEFEARRQQHEQLNE---AAQGILTGPGDVSLSTSQVQKELQSINQKWVELTDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLS-----------------------------------VQSAISTQPEAVKQQLEETSEIRSDLEQLDHEVKEAQTLCDELSVLIGEQYLDELKKRLETVALPLQGLEDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQQAK----------NCPISAKLERLQSQLQENEEFQKSLNQHSGSYEVIVAEGESLLLSVPPGEEKRTLQNQLVELKNH................................. 271
63 -10.400sp|P11055|MYH3_HUMAN Myosin-3 OS=Homo sapiens GN=MYH3 PE=1 SV=3  ali   14  21...........................................................................................................................KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE----SGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKL-----------------------------------------------------------EQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILD-LENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEERATRAKTEKQRSDYARELEELSRLEEAGGVTSTQIELNKKREAEFLKLRRDLEE------ATLQHEAMVAALRKKHAD.............................. 299
64 -10.300sp|P13533|MYH6_HUMAN Myosin-6 OS=Homo sapiens GN=MYH6 PE=1 SV=5  ali   11  1..............................................................................................................................................SVAELGEQIDNLQRVKQKLEKEKSEFKLEL-VTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNRQLEEKEALISQLTRGKLSYTQQMEDLKRQLE-------------------------------EEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVEDKKQRNFDKILAE------QKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLE................................................... 298
65 -10.300sp|Q8WXH0|SYNE2_HUMAN Nesprin-2 OS=Homo sapiens GN=SYNE2 PE=1 SV=3  ali   7  1..........................................................................................................................EKNCQDKLETSLHVLNQIKSQLQQPLKHIQNEKDNCEAFQEQVWAEMCSIAVTAIEKQREENSSEASDVETKLRE-FEDLQMQLNTSIDLRTNVLNDAYENLTRYKEAVTRAVESITSLEAIII---------------------------------------------PYRVDVGNPEESLEMPLRKQEELESTVAHIQDLTEKLGMISSPELQYTLQELVSKNSAMKEAFKAQETEAERYLENYKCYRKMEEDIYTNLSKMETVLGQ---------SMSSLPLSYREALERLEQSKALVSNLISTKEELMKLRQILRLLRLRCTENDGI-CLLKIVSALWEK................................. 299
66 -10.300sp|Q8NF91|SYNE1_HUMAN Nesprin-1 OS=Homo sapiens GN=SYNE1 PE=1 SV=3  ali   10  2.....................................................................................................................................................EKKNEVHKVEMFLGELLAARESLKLSQRGQLLSEEGHGAGQEGRLCSQ-LLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWFWVKAIQDRLA-----------------------------------CAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLNMAIGKGEQALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLEQWMESVDQKIEH----------PLQPQPGLKEKFVLLDHLQSILSEAEDHTRALHRLIAKSREL---YEKTEDESFKDTAQEELKTQ................................. 270
67 -10.300sp|Q66GS9|CP135_HUMAN Centrosomal protein of 135 kDa OS=Homo sapiens GN=CEP135 PE=1 SV=2  ali   10  1.........................................................................................................................................ANLQENLANKEKAVAQMKIMISECESSVNQLKETLVNRDR--EINSLRRQLDAAHKELDEVAFKENRRLQDDLATMARENQEISLELEAAVQEKEEMKSRVHKYITEVSRWESLMA------------------------AKEKENQDLLDRFQMLHNRAEDWEVKAHQAEGESSSVRLELLSIDTERRHLRERVEL-LEKEIQEHINAHHAYESQISSMAKAMSRLEEELRHQEDEKATVLNDLSSLRELCIKLDSG--KDIMTQQLNSKNLEFERVVVELENVKSESDLLKKQLSNERHTVKNLESLLATNRD............................................... 292
68 -10.200sp|Q66GS9|CP135_HUMAN Centrosomal protein of 135 kDa OS=Homo sapiens GN=CEP135 PE=1 SV=2  ali   10  3.................................................................................................................................KSELEKTIEHLTCVNHQLESEKYELKSKVLIMKETIESLENKLKVQAQKFSHVAGD-----------SHQKTEVNSLRIVNEQLQRSVDDYQHRLSIKRGELESAQAQIKILEEKIDELNLKMT--------------------------------------SQDEEAHVMKKTIGVIDKEKDFLQETVDEKTEKIANLQENLAN-KEKAVAQMKIMISECESSVNQLKETLVNRDREINSLRRQLDAAHKELDEVGRSREIAFKE--NRRLQDDLATMARENQEISLELEAAVQEKEEMKSRVHKYITEVSRWESLMAAKEKENDLLDRFQMLHNRAEDWEVKAHQA...................... 300
69 -10.200sp|P07951|TPM2_HUMAN Tropomyosin beta chain OS=Homo sapiens GN=TPM2 PE=1 SV=1  ali follow..  10  2...........................................................................................................................DAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSES-EAQEKLEQAEKKATDAEADVASLNRRIEEELDRAQERLATALQKLEEAEKAADESERGMK---------------------------------------------VIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVI-LEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEK--LKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITS.................................................. 283
70 -10.200sp|Q08378|GOGA3_HUMAN Golgin subfamily A member 3 OS=Homo sapiens GN=GOLGA3 PE=1 SV=2  ali   10  48.......................................................................................................................QEIPADTLGQFPSIKDVLQAAAAEHQDQGQEVNGEVRSRRDSICSSVSLESSAAETQEEML-----------------QVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSH---------------------------------------------SSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLA-SSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTT---------LTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQ....................................................... 300
71 -10.200sp|P07942|LAMB1_HUMAN(removed signalp:1-21) Laminin subunit beta-1 OS=Homo sapiens GN=LAMB1 PE=1 SV=2  ali   12  18..........................................................................................................................................QLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKEDIQGTQNLLTSIESETAASEETLFNASQRIS---------------------------------------------ELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTL-------------------------------AQANSKLQLLKDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQK................................................. 257
72 -10.200sp|P46939|UTRO_HUMAN Utrophin OS=Homo sapiens GN=UTRN PE=1 SV=2  ali   11  2.........................................................................................................................................STVTEVDMDLDSYQIALEEVLTWLLSAEDTFQEQDDISDDVEEVKDQFATHEAFMMELTGSVLQAGNQLITQGTLSDEEEFEIQEQMTLLNARWEALRVESMDRQSRLH--------VLMELQKKQLQQLSAWLTLTEERIQKMETCPLDDDVKSLQKLLEEHKSLQSDLEAEQVKVNSLTHMVVIVDENSGESATAILEDQLQKLGERWTAVCRWTEERWNRLQEINILWQELLEEQCLLKAWLTEKEEALNK---------VQTSNFKDQKELSVSVRRLAILKEDMEMKRQTLDQLSEIGQDV........................................................ 297
73 -10.200sp|Q5T9S5|CCD18_HUMAN Coiled-coil domain-containing protein 18 OS=Homo sapiens GN=CCDC18 PE=1 SV=1  ali   10  1..................................................................................................................................EKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIR-------GELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTAR------------------------QVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKE-LEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTT--IKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEME............................................ 292
74 -10.200sp|Q8NF91|SYNE1_HUMAN Nesprin-1 OS=Homo sapiens GN=SYNE1 PE=1 SV=3  ali   9  5..........................................................................................................................................DLCSIGKEHVFSLEAKVKDHEDYNSELQEVEKWLLQMSGRLVAPDLLETSSLETKAMMEEIAGFEDRLNNLQMKGDTLIGQVHAHLQGTKDSYSAICSTAQRMYQSLEHELQKHV--------------------------QDTLQQCQAWLSAVQPDLEPSPQPPLSRAEAIKQVKRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQQTEQTIEQKLVQAQNLTQGWEEIKHLKSELWIYLQDADQQLQNMKRRH--------SELELNIAQNMVSQVKDFVKKLQSKQASVNTIIEKVNKLT....................................................... 300
75 -10.200sp|Q15075|EEA1_HUMAN Early endosome antigen 1 OS=Homo sapiens GN=EEA1 PE=1 SV=2  ali   11  1..................................................................................................................KEQQVADLQLKLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQK-----------QNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQ------------------------SESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQE----------------HCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKE............................................ 297
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Liu T, Rojas A, Ye Y, Godzik A. Homology modeling provides insights into the binding mode of the PAAD/DAPIN/pyrin domain, a fourth member of the CARD/DD/DED domain family. Protein Sci. 2003 Sep;12(9):1872-81.