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Query: sp|Q9Y236|OSGI2_HUMAN Oxidative stress-induced growth inhibitor 2 OS=Homo sapiens GN=OSGIN2 PE=2 SV=1, from H.sapiens

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPLVEETSLLEDSSVTFPVVIIGNGPSGICLSYMLSGYRPYLSSEAIHPNTILNSKLEEARHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHHYIPHVVLGKGPPGGAWHNMEGSMLTISFGSWMELPGLKFKDWVSSKRRSLKGDRVMPEEIARYYKHYVKVMGLQKNFRENTYITSVSRLYRDQDDDDIQDRDISTKHLQIEKSNFIKRNWEIRGYQRIADGSHVPFCLFAENVALATGTLDSPAHLEIEGEDFPFVFHSMPEFGAAINKGKLRGKVDPVLIVGSGLTAADAVLCAYNSNIPVIHVFRRRVTDPSLIFKQLPKKLYPEYHKVYHMMCTQSYSVDSNLLSDYTSFPEHRVLSFKSDMKCVLQSVSGLKKIFKLSAAVVLIGSHPNLSFLKDQGCYLGHKSSQPITCKGNPVEIDTYTYECIKEANLFALGPLVGDNFVRFLKGGALGVTRCLATRQKKKHLFVERGGGDGIALast
1 -126.000sp|Q9Y236|OSGI2_HUMAN Oxidative stress-induced growth inhibitor 2 OS=Homo sapiens GN=OSGIN2 PE=2 SV=1  ali  100  1MPLVEETSLLEDSSVTFPVVIIGNGPSGICLSYMLSGYRPYLSSEAIHPNTILNSKLEEARHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHHYIPHVVLGKGPPGGAWHNMEGSMLTISFGSWMELPGLKFKDWVSSKRRSLKGDRVMPEEIARYYKHYVKVMGLQKNFRENTYITSVSRLYRDQDDDDIQDRDISTKHLQIEKSNFIKRNWEIRGYQRIADGSHVPFCLFAENVALATGTLDSPAHLEIEGEDFPFVFHSMPEFGAAINKGKLRGKVDPVLIVGSGLTAADAVLCAYNSNIPVIHVFRRRVTDPSLIFKQLPKKLYPEYHKVYHMMCTQSYSVDSNLLSDYTSFPEHRVLSFKSDMKCVLQSVSGLKKIFKLSAAVVLIGSHPNLSFLKDQGCYLGHKSSQPITCKGNPVEIDTYTYECIKEANLFALGPLVGDNFVRFLKGGALGVTRCLATRQKKKHLFVERGGGDGIA 505
2 -105.000sp|Q9UJX0|OSGI1_HUMAN Oxidative stress-induced growth inhibitor 1 OS=Homo sapiens GN=OSGIN1 PE=2 SV=2  ali follow..  49  84MSSSRKDHLGASSSEPLPVIIVGNGPSGICLSYLLSGYTPYTKPDAIHPHPLLQRKLTEAPGVSILDQDLDYLSEGLEGRSQSPVALLFDALLRPDTDFGGNMKSVLTWKHRKEHAIPHVVLGRNLPGGAWHSIEGSMVILSQGQWMGLPDLEVKDWMQKKRRGLRNSRATAGDIAHYYRDYVVKKGLGHNFVSGAVVTAVEWGTPDP---------------SSCGAQDSSPLFQVSGFL-TRNQAQQPFSLWARNVVLATGTFDSPARLGIPGEALPFIHHELSALEAATRVGAVTPASDPVLIIGAGLSAADAVLYARHYNIPVIHAFRRAVDDPGLVFNQLPKMLYPEYHKVHQMMREQSI-LSPSPYEGYRSLPRHQLLCFKEDCQAVFQDLEGVEKVFGVSLVLVLIGSHPDLSFLPGAGADFAVDPDQPLSAKRNPIDVDPFTYQSTRQEGLYAMGPLAGDNFVRFVQGGALAVASSLLRKETRKP............ 559
3 -40.600sp|P31513|FMO3_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 3 OS=Homo sapiens GN=FMO3 PE=1 SV=5  ali follow..  10  1...........................................................................................MGKKVAIIGAGVSGLASIRSCLEEGLEPTCFEKSNIGGLWASIYKSVFSNSSKEMMCFPDFPFPD--------DFPNFMHNSKIQEYIIAFAKEKNLLKYIQFKTFVSSVNKHPDFA----------------------TTGQWDVT-----TERDGKKESAVFDAVMVCSGHHVYPNLPKESFPGLN--HFKGKCFHSRDYKEPGVFNGKRVLVVGLGNSGCDIATELSRTAEQVMISSRSGSWVMSRVWDNGYPWDMLLVTRFGTFLKNNLPLMPLNGVLRKEPVFNDELPASILCGIVSVKPEDGTIFE-GIDCVIFATGYSFAYPFLDESIIKSRNNEIILFKGVFPP---------LLEKSTIAVIGFVQ-GAAIPTVDLQSRWAAQVIKGTCTLPSMEDMMNDINE.. 411
4 -40.500sp|Q99518|FMO2_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 2 OS=Homo sapiens GN=FMO2 PE=1 SV=3  ali follow..  11  1...........................................................................................MAKKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEIGGVWASIYQSVVTNTSKEMSCFSDFPMPE--------DFPNFLHNSKLLEYFRIFAKKFDLLKYIQFQTTVLSVRKCPDF----------------------SSSGQWKVVT-----QSNGKEQSAVFDAVMVCSGHHILPHIPSFPGME----RFKGQYFHSRQYKHPDGFEGKRILVIGMGNSGSDIAVELSKNAAQVFISTRHGTWVMSRISEDGYPWDSVFHTRFRSMLRNVLPLEPQNKYIMKEPVLNDDVPSRLLCGAIKVKSTEDGTVEENIDVIIFATGYSFSFPFLEDSLVKVENNMVSLYKYIF---------PAHLDKSTLACIGLIQ-GSIFPTAELQARWVTRVFKGLC---SLPSERTMMMDII 410
5 -40.400sp|P31512|FMO4_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 4 OS=Homo sapiens GN=FMO4 PE=2 SV=3  ali follow..  10  1...........................................................................................MAKKVAVIGAGVSGLSSIKCCVDEDLEPTCFERSDIGGLWTRVYKSLVTNVCKEMSCYSDFPFHE--------DYPNFMNHEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDF----------------------SETGQWDVVT-----ETEGKQNRAVFDAVMVCTGHFLNPHLPAFPGIH----KFKGQILHSQEYKIPEGFQGKRVLVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSSDWGYPYNMMVTRRCCSFIAQVLPSLSITKGKKAKFIVNDELPNCILCGAITMKTEDGTVEE-NIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKQVF-----------NLERATLAIIGLIG-GSILSGTELQARWVTRVFKGLCKIPPSQKLMMEATE.. 410
6 -40.400sp|O60774|FMO6_HUMAN(removed signalp:1-17) Putative dimethylaniline monooxygenase [N-oxide-forming] 6 OS=Homo sapiens GN=FMO6P PE=5 SV=1  ali follow..  10  1............................................................................................................IWCCLEEGLEPTCFERSDVGGLWASIYQSVFTNSSKEMMCFPDFPYPD--------DYPNYIHHSKLQEYIKTYAQKKDLLRYIQFETLVSGIKKCPSF----------------------LVTGQWVVV-----TEKDGKQESTIFDAVMICSGHHVYPNLPTDSFPGLD--QFRGNYLHSRDYKNPEAFKGKRVLVIGLGNSGSDIAVELSRLATQVIISTRSASWVMSRVWDDGYPWDMMYVTRFASFLRNVLPLMPLNGSLRKEPVFNDELPSRILCGTLSIKPEDGTMFE-AIDSVIFATGYDYSYPFLDETIMKSRNNEVTLFKGIFPP---------LMEKPTLAVIGLVQ-GAAIPTADLQAWWAAKVFANSCTLPTTNEMMDDTDE.. 394
7 -40.100sp|P49326|FMO5_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 5 OS=Homo sapiens GN=FMO5 PE=2 SV=2  ali follow..  11  1..........................................................................................MTKKRIAVIGGGVSGLSSIKCCVEEGLEPVCFERTDIGGLWASIYKSVIINTSKEMMCFSDYPIPD--------HYPNFMHNAQVLEYFRMYAKEFDLLKYIRFKTTVCSVKKQPDF----------------------ATSGQWEVVT-----ESEGKKEMNVFDGVMVCTGHHTNAHLPSFPGIE----KFKGQYFHSRDYKNPEGFTGKRVIIIGIGNSGGDLAVEISQTAKQVFLSTRRGAWILNRVGDYGYPADVLFSSRLTHFIWKICGLKPKHRALSQHPTLNDDLPNRIISGLVKVKGNEDGSREDDIDAVIFATGYSFDFPFLEDSVKVVKNKISLYKKVFPPNL----------ERPTLAIIGLIQPGAIMPISELQGRWATQVFKGLKTLPSQSEMMAEISK.. 411
8 -40.100sp|Q01740|FMO1_HUMAN Dimethylaniline monooxygenase [N-oxide-forming] 1 OS=Homo sapiens GN=FMO1 PE=2 SV=3  ali follow..  13  1...........................................................................................MAKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSDLGGLWASLYKSVVSNSCKEMSCYSDFPFPE--------DYPNYVPNSQFLEYLKMYANHFDLLKHIQFKTKVCSVTKCSDS----------------------AVSGQWEVVTMHEEKQESA-----IFDAVMVCTGFLTNPYLPSFPGIN----AFKGQYFHSRQYKHPDIFKDKRVLVIGMGNSGTDIAVEASHLAEKVFLSTTGGGWVISRIFDSGYPWDMVFMTRFQNMLRNSLPLIPEDRTQLKEFVLNDELPGRIITGKVFIRPSNNTSKEEPIDIIVFATGYTFAFPFLDESVVKVEDGQASLYKYIF---------PAHLQKPTLAIIGLIK-GSMIPTGETQARWAVRVLKGVNK---LPPPSVMIEEIN 410
9 -33.900sp|Q8IWF2|FXRD2_HUMAN(removed signalp:1-26) FAD-dependent oxidoreductase domain-containing protein 2 OS=Homo sapiens GN=FOXRED2 PE=1 SV=1  ali   17  2.............PPRRDYCVLGAGPAGLQMAYFL-----------------------------------------------------------------------------QRAGRDYAVFERAPPGSFFTRYPRHRKLISINKLSHDPRLLFRHYSRA--------FPDARDMVRYLGDFADTLGL--RVQYNTTIAHVTLDKDR-------------------------QAWNGHYFILTDQKGQ---VHQCSVLFVATG-LSVPNQVDFPGSEY----------YESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSWA..................................................................................................................................................................... 226
10 -33.100sp|Q8IWF2|FXRD2_HUMAN(removed signalp:1-26) FAD-dependent oxidoreductase domain-containing protein 2 OS=Homo sapiens GN=FOXRED2 PE=1 SV=1  ali   11  2.................................................................................................................................................................................................................................................................LFVATG-LSVPNQVDFPGSEY----------YESVSVDPEDFVGQNVLILGRGNSAFETAENILGVTNFIHMLSRSRVRLSWATHYVGDLRAINNGLLDTYQLKSTDLAILKDSKGKFHVTPKFFLEEANTNQSADSITLPNFAMRVPYDRVIRCLGWNFDFSIFNKSLRLNSGNAFGKKYPLIRA------SYESKGSRGLFILGTASAGGFIHGFRYTVRAVHRLLEHRHHSVTWPATELPITQLT 257
11 -24.000sp|Q12882|DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2  ali   13  4................................................................................................................................................................................................................................................................................YTSKDFLPLVAKGSKAGMCACHSPLPSIRGVVIVLGAGDTAFDCATSALRCGARVFIVFRKGFVNIRAVPEEMELAKEEKCEFLPFLSPRKVIVKGG-------RIVAMQFVRTEQDETGKWNEDEDQMVHLKADVVISAFGSVLSDPKVKEALSPIKFN-------RWGLPEVDPETMQ-TSEAWVFAGGDVVLANTTVESVNDGKQASWYIHKYVQSQYGASVSAKP.... 219
12 -21.500sp|P00390|GSHR_HUMAN Glutathione reductase, mitochondrial OS=Homo sapiens GN=GSR PE=1 SV=2  ali follow..  12  50.PQPQGPPPAAGAVASYDYLVIGGGSGGLASARRAA-----------------------------------------------------------------------------ELGARAAVVESHKLGGTCVNVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFN-------RVIKEKRDAYVSR--LNAIYQNNLTKSHIEIIRGHAAFTSDPKPTI----------------------------EVSGKKYTAPHILIATGGMPSPHESQIPGASLGITSDGFFQLEEL----------GRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDK---------LRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAV---GRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKG---------HIIVDEFQNTNVKGIYAVGDVCGKALLTPAIAAGRKLAHRLFEYKEDSKL........... 406
13 -20.800sp|Q12882|DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2  ali   12  33...........SEAYSAKIALFGAGPASISCASFLAGYSDI-----------------------------------------------------------------------------TIFEKQEYVGGLST--------------SEIPQFRLP-----------------YDVVNFEIELMKDLGVK--IICGKSL------------------------------------------SVNEMTLSTLKEKGYKAAFIGIGL-PEPNKDAIFQTQDQGFYTSKDFLPLVACHSPLPSIRGVVIVLGAGDTAFDCATSALRCGARVFIVFRKGFVNIRAVPEEMELAKEEKCEFLPFLSPRKVIVKGG-------RIVAMQFVRTEQDETGKWNEDEDQMVHLKADVVISAFGSVLSDPKVKEA................................................................................ 300
14 -20.000sp|Q86VQ6|TRXR3_HUMAN Thioredoxin reductase 3 (Fragment) OS=Homo sapiens GN=TXNRD3 PE=1 SV=3  ali   13  24.................................................................................................................................................................................................................................................KATNKKGQETYYTAAQFVIATG--ERPRYLGIQGDK--------EYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGFGLDVTVMVRSI----------LRGFDQEMAEKVGSYMEQHGVKFLRKFIP-------VMVQQLEKGSPGKLKTEGTETIEGVYNTVLLAIGRDSCTRKIGLEKIGVKINEKS---------KIPVNDVEQTNVPYVYAVGDILEDKLTPVAIQSGKLLAQRLFGASLEK............. 247
15 -19.400sp|Q16881|TRXR1_HUMAN Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens GN=TXNRD1 PE=1 SV=3  ali   15  2............................................................................................................................................................................................................................................................YSAERFLIATG--ERPRYLGIPGDK--------EYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSI----------LRGFDQDMANKIGEHMEEHGIKFIRQFVP-------IKVEQIEAGTPGRLRTNSEEIIEGEYNTVMLAIGRDACTR-LETVGVKINEKTG----------KIPVTDEEQTNVPYIYAIGDILEDKLTPVAIQAGRLLAQRLYAGSTVK............. 214
16 -19.000sp|P22570|ADRO_HUMAN(removed signalp:1-24) NADPH:adrenodoxin oxidoreductase, mitochondrial OS=Homo sapiens GN=FDXR PE=1 SV=3  ali follow..  11  9..........STQEKTPQICVVGSGPAGFYTAQHL----------------------------------------------------------------------------LKHPQAHVDIYEKQPPFGLVRF------------------------------GVAPDHPEVKNVINTFTQTAHSGRCA-NVEVGRDVT-------------------------------------------------PELREAYHAVVLSYGA-EDHRALEIPGEELPGVCSARAFVLPENQELEPDLSCDTAVILGQGNVALDVARILLTPPEHVWLVGRRGPLQVAFTIKELRERQASASRAWGLRFFRSPQQVLPSPDGRRAAGVRLAVTRLEGVDEATRAVPTGDMEDLPCGLVLSSIGYKSR-------------PVDPSVPFDSKLGVIPNVEGRVMDVPGLYCSGWVKGPTVIATTMTDSFLTGQMLLQDLKAGLLPSGPRP..... 412
17 -18.700sp|Q9NNW7|TRXR2_HUMAN Thioredoxin reductase 2, mitochondrial OS=Homo sapiens GN=TXNRD2 PE=1 SV=3  ali follow..  11  27...RGAARGAAAGQRDYDLLVVGGGSGGLACA-------------------------------------------------------------KEAAQLGRKVAVVDYVEPSPQG-------TRWGLGGT----------------VNVGCIP------------KKLMHQAALLGGLIQD-APNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVK--FNIKASFVDEHTVCGVAKGGKEILLSADHIIIATG--GRPRYPTHIEGALEYGITSDDIFW-------LKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMR------SIPLRGFDQQMSSMVIEHMA-------------SHGTRFLRGCAPSRVRRLPDGQLQSTTGKEDTGTFDTVLWAIGRVPDTR-LEKAGVDTSPDTQ----------KILVDSREATSVPHIYAIGDVVEGRLTPIAIMAGRLLVQRLFGGSSDL............. 389
18 -18.300sp|Q9BRQ8|AIFM2_HUMAN Apoptosis-inducing factor 2 OS=Homo sapiens GN=AIFM2 PE=2 SV=1  ali follow..  11  2......GSQVSVESGALHVVIVGGGFGGIAAASQLQ-----------------------------------------------------------------------------ALNVPFMLVDMKD----FHHNVAALRASVETGFAKKTFISYSVTFKDNF-------------------------------RQGLVVGID-------------------------------------LKNQMVLLQGGEALPFSHLILATGSTGP---------KFNEVSSQQAAIQAYEDMVRQVQRSRFIVVVGGGSAGVEMAAEIKTEEKEVTLIHSQVALADKELLPSVRQEVKEILLRK-----------------GVQLLLSERVSNLEELEYIKVQTDKGTE--VATNLVILCTGIKINSSAYRKA---------ESRLASSGALRVNE-HLQVEGHSNVYAIGDCADPKMAYLAGLHANIAVANIVNSVKQRPLQAYKPGALTF. 328
19 -17.200sp|P09622|DLDH_HUMAN Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens GN=DLD PE=1 SV=2  ali follow..  13  29...AVPLRTYADQPIDADVTVIGSGPGGYVAAIKAA-----------------------------------------------------------------------------QLGFKTVCIEKNELGGTCLNV---IPSKALLNNSHYYHMAHGKDFASRGIEMSEVRLNLDKMMEQKSTAVKA--LTGGIAHLFKQNKVVHVNGYGKITGKNQ--------------------------TATKADGGTQVIDTKNILIATG--SEVTPFPGITIDEDTIVSSTGALS-------LKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAV--------EFLGHVGGVGIDMEISKNFQRILQKQ---------GFKFKLNTKVTGATKKSDGKIDASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDPRG---------RIPVNTRFQTKIPNIYAIGDVVAGPMLAHAEDEGIICVEGMAGG................. 380
20 -17.100sp|Q96NN9|AIFM3_HUMAN Apoptosis-inducing factor 3 OS=Homo sapiens GN=AIFM3 PE=1 SV=1  ali   18  30.VMAKCISPSAGYSSSTNVLIVGAGAAGLVCAETLEG---------------FSDRIVLCTLDRHLPYDRPKLSKSL--------------------DTQPEQLALRPKEFFRAYGIE-------------------------------------------------------------------------VLTEAQVVTVDVRTKK--------------------------------------VFKDGFKLEYSKLLLAPG--SSPKTLSCKGKEVENVFTIRTPEDA--NRVVRLARGRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFEN-----------------NRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGFIP..................................................................... 300
21 -17.000sp|Q16881|TRXR1_HUMAN Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens GN=TXNRD1 PE=1 SV=3  ali   11  2..................................................................................NGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDRWGLGGT----------------VNVGCIP------------KKLMHQAALLGQALQD-SRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVV--ENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATG--ERPRYLGIPGDK--------EYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSI----------LRGFDQDMANKIGEHMEEHGIKFIRQFVP-------IKVEQIEAGTPGRLRTNSEEIIEGEYNTVMLAIGRDACTRKI................................................................................... 300
22 -16.800sp|O95831|AIFM1_HUMAN Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens GN=AIFM1 PE=1 SV=1  ali   16  96.......................................................................................................................................................................................................................................................NDGSQITYEKCLIATG--GTPRSLSAAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRR-----------------EGVKVMPNAIVQSVGSSGKLLIKLKDGR--KVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNA-----------ELQARSNIWVAGDAA....................................... 290
23 -16.700sp|Q9Y6N5|SQRD_HUMAN Sulfide:quinone oxidoreductase, mitochondrial OS=Homo sapiens GN=SQRDL PE=1 SV=1  ali follow..  13  28GPLQLHTGASHAARNHYEVLVLGGGSGGITMAARMK-------------------RKVGAENVAIVEPSERHFYQ--------PIWTLVGAGAKQLSSSGRPTASVI------PSGVEWI--------------------------------------------------------------------------KARVTELNPDKN-----------------------------CIHT--------DDDEKISYRYLIIALGI--QLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADALQEIIQERN-----LTVNYKKNLIEVRADKQEAVLDKPGETQVISYEMLHVTPPMSPP-DVLKTSPVA----------DAAGWVDVDKETLQHRRYPNVFGIGDCTNSKTAAAVAAQSGILDRTISVIMKNQTPTKKYDGYTS.. 378
24 -16.700sp|Q96NN9|AIFM3_HUMAN Apoptosis-inducing factor 3 OS=Homo sapiens GN=AIFM3 PE=1 SV=1  ali   14  1...........................................................................................................................................................................................................................................................................PKTLSCKGKEVENVFTIRTPEDANRVVRLA--RGRNVVVVGAGFLGMEVAAYLTEKAHSVSVVELEETPFRRFLGERVGRALMKMFEN-----------------NRVKFYMQTEVSELRGQEGKLKEVVLKSSKVVRADVCVVGIGAVPATGFLRQSGIGLDSRGF-----------IPVNKMMQTNVPGVFAAGDAVT-PHWQMAHAQGRVAAQNMLAQ................. 203
25 -15.900sp|Q8WU10|PYRD1_HUMAN Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 OS=Homo sapiens GN=PYROXD1 PE=1 SV=1  ali follow..  10  2.......EAARPPPTAGKFVVVGGGIAGVTCAEQLATHFP--------------------------SEDILLVTASPVIKAVTNFKQISKIL-----------------------------------------------------------------------------EEFDVEEQSSTMLGKRFPNIKVI--ESGVKQLKSEEHC---------------------------------------TEDGNQHVYKKLCLCAGA-----KPKLICEGNPYVL-GIRDTDSAQEFQKQLTKAKRIMIIGNGGIALELVYEI--EGCEVIWAIKDKAIGNTFFDAGAAEFLTSKLIAEVKKIYLQDEFRILKKKSFTFPRDHKSVTADTEMWPVYVELTNEK--IYGCDFIVSATGVTPNVEPFHGNSFDLGEDGG-----------LKVDDHMHTSLPDIYAAGDICT-RLWTQARQMGWYAAKCMAAASSGDSIDM......... 401
26 -14.800sp|Q8NHU2|CT026_HUMAN Uncharacterized protein C20orf26 OS=Homo sapiens GN=C20orf26 PE=2 SV=3  ali   10  7.......................................................................................................................................................................................................................................................STDEIVPYDHLILCTGQ--QYQVPCPTEADISQHHFTLNEEEDCFKRNNSITTEGNIIVYGNTIDTYTTVETLLNLGVSGSRIHLVQPPPASTITCINNYSV-------------ESAVADALGAAGVTMYRDAILAQWNDGLYSASFTTPTKPFRLQCSMFFSFCEKNVDYETLNDACLVYD-----------SRLVIDTN---HTNDIAIRAAGSLT-SNEWTHSNFSSKEIGFQLAAAMLHL............. 263
27 -13.500sp|O95831|AIFM1_HUMAN Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens GN=AIFM1 PE=1 SV=1  ali   14  1.............................................................................................................................................................................................................................................................................................................KSITIIGGGFLGSELACALGRKGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRR-----------------EGVKVMPNAIVQSVGSSGKLLIKLKDGRK--VETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNA-----------ELQARSNIWVAGDAAGRRRVEHAVVSGRLAGENMTGAAK............... 174
28 -13.400sp|Q86VQ6|TRXR3_HUMAN Thioredoxin reductase 3 (Fragment) OS=Homo sapiens GN=TXNRD3 PE=1 SV=3  ali   13  35.....QKLLQEDLAYDYDLIIIGGGSGGLSCA-------------------------------------------------------------KEAAILGKKVMVLDFVVPSPQG-------TSWGLGGT----------------VNVGCIP------------KKLMHQAALLGQALCD-SRKFGWEYNQQVRHNWETMTKAIQNHISSLNWGYRLSLREKAVA--VNSYGEFVEHHKIKATNKKGQETYYTAAQFVIATG--ERPRYLGIQGDK--------EYCITSDDLFSLPYCPGKTLVVGASYVALECAGFLAGFGLDVTVMVRSI........................................................................................................................................................................... 256
29 -11.200sp|Q6NUM9|RETST_HUMAN(removed signalp:1-18) All-trans-retinol 13,14-reductase OS=Homo sapiens GN=RETSAT PE=2 SV=2  ali follow..  10  35.KVLKQAFSANQVPEKLDVVVIGSGFGGLAAAAILAGKRVLVLEQHTKAGGCCHT----GKNGLEFDTGIHYIGRMEEGSI-APLSSPFDIMVLEGPNGRKEYPMYSGEKAYIQGLKEKFPQEEAII-KLVKVVSSGAPHAILLKFLPLPVVQLLDRCGLLTRFSPFLQASTQSLAEVLQQLGASSELQAAVLTKATVQSVLLDSAGKACGVSVKKGHELVNIYCPIVVSNAGLFNTARCLPGVKQQLGTVRPGLGMTSVFICLRGTKEDLHLPSTNYYVYYDT-QAMERYVSMPREEAAEHIPLLFFAFPSAKDPTWEDRFPGRSMIMLIPTAYEWFEEWQAELKGKRGSDYETFKNSFVEASMSVVLKLFPQLEGKVESVTAGSPLTNQFYLAAPRGA-----------CYGADHDLGRLHPCVMASLRAQ--------------------SPIPNLYLTGQDIFTCGLVGALQGALLCSSAILKRNLYSDLKNLDSR..... 584
30 -10.400sp|Q16134|ETFD_HUMAN Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial OS=Homo sapiens GN=ETFDH PE=1 SV=2  ali   11  58.....EGVNMERFAEEADVVIVGAGPAGLSAAVRLK-----------------------------------------------------------------------QLAVAHEKDIRVCLVEKAAQIGAHTLSGACLDPGAFKELFPDYRIPVPILPGLPMNNHGNYIVRLGHLVSWMGEQAEALGVE--VYPGYAAAEVLFHDDGSVKGIATNDV------------------GIQKDGAPKATFERGLELHAKVTIFAEGCHG............................................................................................................................................................................................................................................... 250
31 -10.200sp|Q8IWF2|FXRD2_HUMAN(removed signalp:1-26) FAD-dependent oxidoreductase domain-containing protein 2 OS=Homo sapiens GN=FOXRED2 PE=1 SV=1  ali   13  1................................................................................................................................................................................................................................................................................................................................................................................................................AMRVPYDRVIRCLGWNFDFSIFNKS-----LRLNSGNAFGKKYPLIRA-SYESKGSRGLFILGTASAGGFIHGFRYTVRAVHRLLEHRHHSVTWPATELPITQLT 107
32 -10.100sp|O94851|MICA2_HUMAN Protein MICAL-2 OS=Homo sapiens GN=MICAL2 PE=1 SV=1  ali   13  74...SHKEYKRGKSCTNTKCLIVGGGPCGLRTAIELA-----------------------------------------------------------------------------YLGAKVVVVEKRD-----SFSRNNVLHLWPFTIHDLRGL--AKKFYGKFCAGSIDHISIRQLQLILFKVALMLGVE--IHVNVEFVKVLEPPEDQENQKIG------------------------WRAEFLPTDHSLSEFEFDVIIGADGRRNTLEGKEFRGKLAIAITANFINRNSTAEAKVEEISGVAFIFN...................................................................................................................................................................................................... 271
33 -9.920sp|Q96RQ9|OXLA_HUMAN(removed signalp:1-21) L-amino-acid oxidase OS=Homo sapiens GN=IL4I1 PE=1 SV=1  ali follow..  9  29......TWGLNRTLKPQRVIVVGAGVAGLVAAKVLSGHKVTILEADNRIGGRIHRILHKLCQGLGLNLTKFTQYDKRPQEKGHSPEDIYQMALNQALKDLKALGCRKAMKKFERHTLLEYLLGEGNLSRPAVQLLGDVMSEDGFFYLSFAEALRAHSCLSDRLQYSRIVGGWDLLPRALLS-----SLSGLVLLNAPVVAMTQGPHD-----------------------------VHVQIETSPPARNLKVLKADVVLLT-----------ASGPAVKRITFSLPRHMQEALRRLHYVPATKVFLIEGGHSNTDRPSRMIREGALLLASYTWS---------------------------DAAAAFAGLSREEALRLALDDVAALHGPVVRQLWDGTGVVKRWAED---HSQGGFVVQP-----------------------PALWQTEKDDWTVPRIYFAGEHTAHGWVETAVKSALRAAIKINSRKGPASDTASPEGHAS.. 501
34 -9.860sp|Q9UL12|SARDH_HUMAN Sarcosine dehydrogenase, mitochondrial OS=Homo sapiens GN=SARDH PE=1 SV=1  ali   16  52.TSVVAQGPSRPLPSTANVVVIGGGSLGCQTLYHLAGMSGAVSGTTWHTAGLLWQLRPSDVEVELLAHTRRVVSRELEEETGLHT--------------GWIQNGGLFIASNRQREYKRLMSLGKAYG--------ESHVLSPAETKTLYPLMNVDDLYGTLYVPHDGTMDPAGTCTTLARAASARGAQ--VIENCPVTGIRVWTDD------------------------------FGVRRVAGVETQHGSIQTPCVVNCAGVWAS-AVGRMAGVKVP.................................................................................................................................................................................................................................. 287
35 -9.850sp|Q7RTP6|MICA3_HUMAN Protein MICAL-3 OS=Homo sapiens GN=MICAL3 PE=1 SV=2  ali   11  1...............................................................................................................................................................................................................................................MEERKHETMNPAHVLFDRFVQATTCKGT-DHLELKPKDYRSFYHKLKSGSHKDYKKGKACTNTKCLIIGAGPCGLRTAIDLSLLGAKVVVIEKRDAFSRNNVLHLWPFTIHDLRGLGAKKFYGQLILLKVALILGIEIHVNVEFQGLIQPPRALVHPKTHPVSEYEFEVIIGGDGRRNTLE..................................................................................... 230
36 -9.690sp|Q8TDZ2|MICA1_HUMAN NEDD9-interacting protein with calponin homology and LIM domains OS=Homo sapiens GN=MICAL1 PE=1 SV=2  ali   10  72...GQPVYQQGRACTSTKCLVVGAGPCGLRVAVELA-----------------------------------------------------------------------------LLGARVVLVEKRT-----KFSRHNVLHLWPFTIHDLRALGAKKFYG-RFCTGTLDHISIRQLQLLLLKVALLLGVE--IHWGVTFTGLQPPPRK----------------------------SGWRAQLQPNPPAQLANYEFDVLISAAGGKFVPEGREMRGKLAIGITANFVNGRTVEETQVPEISGVARIYN...................................................................................................................................................................................................... 266
37 -9.540sp|Q9P0Z9|SOX_HUMAN Peroxisomal sarcosine oxidase OS=Homo sapiens GN=PIPOX PE=2 SV=2  ali follow..  10  1.........MAAQKDLWDAIVIGAGIQGCFTAYHLARKLPHSRGSSHGQSRIIRKAYLEDFYTRMMHECYQIWAQ-LEHEAGTQLHRQTGLLL-----LGMKENQELKQANLSRQRVEHQCLSSEELKQRF------------------PNIRLPRGEVGLLDNSGGVIYAYKALRALQDA-IRQLGGI--VRDGEKVVEINP-------------------------------------GLLVTVKTTSRSYQAKSLVITAGPWTNQLLRPL-GIEMPLQTLRINVCYWREMVPGSYGVSQAFLWLGLCPHHIYGLPTGEYPGLMKVSYHHGNHADPEERDCPTARTDIGDVQILSSFVRDHLPDLKPEPAVIES------MYTNTPDEQFILDRHPK------YDNIVIGAGFSGH-----------------------------------------FKLAPVVGKILYELSMKLTPSY........................ 372
38 -9.470sp|Q9UHG3|PCYOX_HUMAN(removed signalp:1-27) Prenylcysteine oxidase 1 OS=Homo sapiens GN=PCYOX1 PE=1 SV=3  ali follow..  8  1.........AELRAPPDKIAIIGAGIGGTSAAYYL--------------------------------------------------------------------------RQKFGKDVKIDLFEREEVGG-------RLATMMVQGQYEAGGSVIHPLN------------------LHMKRFVKDLGLSAVWRYGFQSLRMHMWVEDVLDKFMRIYRYQSHDYAFSSVEKLLHALGGDDFLGMLNRTLLET-------LQKAGFSEKFLNEMIAPVMRVNYGQSTDINAFVGAVSLSCSDSGLWAVEGGNKLVCSGLLQASKSNLISGSVMY------------------------------------------IEEKTKTKYTGNPTKMYEVVYQIGTETRSDFYDIVLVATPLNRKMSNITFLNFDPPIEEFHQYYQHIVTTLVKGEL-SIILHDRLYYLNGIEC-SAMEMSAIAAHNAALLAYHRWNGHTDMIDQDGLYE.. 472
39 -9.380sp|Q14534|ERG1_HUMAN(removed signalp:1-43) Squalene monooxygenase OS=Homo sapiens GN=SQLE PE=2 SV=3  ali follow..  10  67..IGTAACTSTSSQNDPEVIIVGAGVLGSALAAVLSGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKD------------------------------LGL--DTVEGLDAQVVNGYMIHDQESKSE------------------------VQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMAEP-NAKFIEGVVLQLLEEDDV------------------------------VMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKVDIRGEMPRNLREYMVESMPASFLPPSSVKKRGVLLLG---DAYNMRHPLTGGG--MTVAFKDIKLWRKLLKGIPDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSATDDSLHQLRKACFLYFKLGGECVA-GPVGLLSVLSPNPLVLIGHFFAVA........................................................................... 484
40 -9.370sp|O15229|KMO_HUMAN Kynurenine 3-monooxygenase OS=Homo sapiens GN=KMO PE=1 SV=2  ali follow..  11  1........MDSSVIQRKKVAVIGGGLVGSLQACFLAN---------------FQIDVYEAREDTRVATFTRGRS----------------------INLALSHRGR---QALKAVGLEDQIVSQGPMRARMIHSLSGKKSAIPYGTKSQYILSV----------------SRENLNKDLLTAAEKYP-NVKMHFNHRLLKCNPEEGM----------------------------------TVLGSDKVPKDVTCDLIVGCDGAYSTVRSHLMKKPRFDYSQQYIPH--TIPPKNGDYAMEPNYLHIWPRNTFMMIALPNMNKSFTCTLFMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKSHCVLL----GDA----AHAIVPFFGQGMNAGFEDCLVFD------ELMDKFSNDLSLCLPVFSRLRIPDDHAISDLS....................................... 360
41 -9.120sp|Q8NBM8|PCYXL_HUMAN(removed signalp:1-22) Prenylcysteine oxidase-like OS=Homo sapiens GN=PCYOX1L PE=1 SV=2  ali follow..  7  1............DAPPGKIAVVGAGIGGSAVAHFL--------------------------------------------------------------------------QQHFGPRVQIDVYEKGTVGGRLATISVN------KQHYESGAASFHSLS------------------LHMQDFVKLLGLRHRIFGGEHFMLEETDWYLLNLFRLWWHYGISFLRLQMWVEEVMEKFM--LYSLGESTFVNMTQHSVAESLLQVGVTQRFIDDVVSAVLRASYGQSAAMPAFAGAMSLAGAQGSLWSVEGGNKLVCSGLLKLTKANVIH----------------------------------------------------ATVTSVTLHSTEQVAYENEVGNSSDFYDIVVIATPLHLDNSSSNLTFAGFHPPQEAAVWRVQSPKPLFRTQLKTL-HDQLFYLNALEW-SSVEVMAVAAKNVALLAYNRWYQDLDKIDQKD..... 463
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;