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Query: sp|Q8WXG1|RSAD2_HUMAN(removed signalp:1-15) Radical S-adenosyl methionine domain-containing protein 2 OS=Homo sapiens GN=RSAD2 PE=1 SV=1, from H.sapiens

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst VFRQPLSSLWRSLVPLFCWLRATFWLLATKRRKQQLVLRGPDETKEEEEDPPLPTTPTSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKEAGMEKINFSGGEPFLQDRGEYLGKLVRFCKVELRLPSVSIVSNGSLIRERWFQNYGEYLDILAISCDSFDEEVNVLIGRGQGKKNHVENLQKLRRWCRDYRVAFKINSVINRFNVEEDMTEQIKALNPVRWKVFQCLLIEGENCGEDALREAERFVIGDEEFERFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCRKGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYIWSKADLKLDWLast
1 -92.6005vsl_A mol:protein length:318 Radical S-adenosyl methionine domain-containing protein 2  ali model follow..  89  15..........................................QETQEDGNSTQRTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGLEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGEYLDILAISCDSFDEQVNALIGRGQGKKNHVENLQKLRRWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGEDALREAERFLISNEEFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKLDW 318
2 -79.9006b4c_A mol:protein length:298 Viperin  ali model follow..  52  3.................................................RVRTGQVPVSVNYHFSRKCNKECLFCFHTATTSHVEKPENAKRGLTLLKQAGMKKINFAGGEPFLYPKF--LGEMIDFCKETLQLESVSIVTNGSLVKEQFLQKHGRNIDILAVSCDSFNEATNIKIGRGSG--DNVQKLYEIGSWCQKYDIKFKLNTVVNKFNHLEDMNDHLNALQPFRWKCFQVLIVTGENDSDKTLRNAHSLTISDDEFDRFCERHSSQTCLVPEPNRLMAKSYLILDEYMRFLDRNGQQP--SKSILEVGVQQALQAVFWDEEAFVERGGIYDWNKSSKDLEW 298
3 -54.5001tv7_A mol:protein length:340 Molybdenum cofactor biosynthesis protein A  ali model follow..  15  2.............................................VEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQID---GIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNI---KATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKH---IEIRFIEFMDVGNDNGWDFSKV-VTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQLITSVSQSFCSTCTRARLSSDGKFYGCLFTVDGFNVKAFIRSGVTDEELKE. 303
4 -45.7006c8v_A mol:protein length:394 Coenzyme PQQ synthesis protein E  ali model follow..  14  1....................................MGSSSSGLVPRGSHMDVIPAPVGLLAELTHRCPLRCPYCSNPLERSAELDTQTWLRVLTEAAGLGVLHVHLSGGEPTARPDIVEITAKCAELGL-----YSNLITSGVGGALAKLDALYDGLDHVQLSVQGVDAANAEKIG---GLKNAQPQKMQFAARVTELGLPLTLNSVIHRGNIHEGFIDLAVKLGAKRLEVAHTQYYGW------AYVNRAALMPDKSQVDESIRIVEAARERLKGQAGGWGRKLMNVTPQGKVLPCHAAETIPGWYVTDHALGEIWTKS......................... 298
5 -44.7005v1q_A mol:protein length:459 Radical SAM  ali model follow..  14  101.....................................LQNARKHVAKLKKHNILSFPLELVIYPSMYCDLKCGFCFLANRERNAKPAKDWERILRQAKDNGVLSVSILGGEPTRYFDIDNLLIACEELKI-----KTTITTNAQLIKKSTVEILAKKYITPVLSLQTLDSKLNFELMGVR-----PDRQIKLAKYFNEVGKKCRINAVYTKQSYEQELVDFCIENKIDRFSVANYSEVTGYTKIKKKYDLADLRRLNEYVTDYITQREANLNFATEGYGCRAKYTKMEIMSNGDILPCIAGVNQTKQNAFEKDLLDVWYDDPL....................... 406
6 -36.5005wgg_A mol:protein length:453 Radical SAM domain protein  ali model follow..  14  40YKNFTAGEIKNKLAHKYNADEIDEALREIESLEAEGLLFSEDPYKEYVSSMDRKSVVKALCLHISHDCNLRCKYCFASTGQRNMMSLEVGKKAIDFLISESGNEIDFFGGEPMMNFDVKGIIEYARQKEKEHNKNRFTLTTNGLLLNDENIKYINENMQNIVLSIDG-RKEVNDRMRIRIDGSGCYDDILPKFKYVAESQDNYYVRGTFTRENMDNDVLHLADE-------------FRQISVEPVVAAKDSGYDLREEDLPRLFEEYEKLAYEYVKRRKESGHEYLAVTPEGDIYPC................................................ 365
7 -36.1004k36_A mol:protein length:392 Anaerobic sulfatase-maturating enzyme  ali model follow..  17  6..........................................................LLIKPASSGCNLKCTYCFYHSKSYGIMRDEVLESMVKRVLNEANGHCSFAGGEPTLAGLFEKLMELQRKHNYKNLKIYNSLQTNGTLIDESWAKFLSENKFLVGLSMDG-PKEIHNLNRKDCCGLDTFSKVERAAELFKKYKVEFNILCVVTSNTARHKVYKYFKEKDFKFLQFINCLD-EEKGKYNYSLKPKDYTKFLKNLFDFWYEDFLNGNRVSIRYFDGLLECQFVVESDGSVYPCDFLDKWRLGNIQDMTMKELFET.......................... 300
8 -34.7006djt_A mol:protein length:331 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase  ali model follow..  15  61....................................................IETHRCIQCTPSVIWCQQNCIFCWRVLSQIKEPKWEEPEVVYEKILAMHKRIAISLSGEPTLYPYLDELIKIFHKNGF-----TTFVVSNGILTDV----IEKIEPTQLYISLDAYDLDSYRRICG--GKKEYWESILNTLDILKEKKRTCIRTTLIRGYNDDLKFVELYERADVHFIELKSYMHV-----GYSQKRLKKEDMLQHDEILKLAKMLDENSSYKLIDDSEDSRVALLQNENRKI................................................... 321
9 -34.5002yx0_A mol:protein length:342 radical sam enzyme  ali model follow..  11  22.............KEVAELFRKQHYEIVGRHSGVKLCHWLKKSLTEGQKFYGIHSHRCLQMTPVLAWCTHNCIFCWRPMGTELPQPWDDPAFIVEESIKANPTHAAISSGEPMLYPYMGDLVEEFHKRGF-----TTFIVTNGTIPEREEMIKEDKLPTQLYVSITAPDIETYNSVNIPMI-PDGWERILRFLELMRDLPTRTVVRLTLVKGENMHSPEKYAKLILKARPMFVEAKAYMFVGYSRNRLTINN--MPSHQDIREFAEALVKHLPGYHIEDEYEPSRVVLIMRD...................................................... 326
10 -31.4004m7s_A mol:protein length:269 BtrN  ali model follow..  15  1....................................................MDKLFSMIEVEVNSQCNRTCWYCVSKRKETGEMDPALYKTLMEQLSSLDAGRISFHFGEPLLCKN---LDLFVGMTTEYIPRARPIIYTNGDFLTEKRLQTLELGIQKFIVTQHAGAKHKFRGVYDQLAGADKEKVVYL........................................................................................................................................................... 142
11 -31.4004m7t_A mol:protein length:270 BtrN  ali model follow..  14  17......................................................KLFSMIEVEVNSQCNRTCWYCVSKRKETGEMDPALYKTLMEQLSSLDAGRISFHFGEPLLCKN---LDLFVGMTTEYIPRARPIIYTNGDFLTEKRLQTLELGIQKFIVTQHAGAKHKFRGVYDQLAGADKEKVVYLDHSDLVLSN.................................................................................................................................................. 165
12 -26.2005tgs_A mol:protein length:263 7-carboxy-7-deazaguanine synthase  ali model follow..  14  4....................SSSGLVPRGSHMAKGIPVLEIFGPTIQGEGMVIGQKTMFVRTA---GCDYSCSWC-SAKKDIRWMTAEEIFAELKDIGGDAFSHVTISGGNPALLKQLDAFIELLKENNI-----RAALETQGTV------QDWFTLIDDLTISPKPPSS----------KMVTNFQKLDHILTSLQENDRAVSLKVVIFNDEDLEFAKTVHKRYPGIPFYL.................................................................................................................. 201
13 -22.2003t7v_A mol:protein length:350 methylornithine synthase PylB  ali model follow..  16  13LGDKVIEGYQLTDNDLRTLLSLE------SKEGLERLYSAARKVRDHYFGNRV----LNCFIYFSTYCKNQCSFCYYNCRNEYRLTMEEIKETCKTLKGAGFHMVDLTMGEPYYYEDPNRFVELVQIVKEELGL--PIMISPGLMDNATLLKAREKGANFLALYQETYDTELYRKLRVGQSFDGRVN----ARRFAKQQGYCVEDGILTGVGNDIESTILGMSTNDPDMVRVMTFLPQEGTPLEGFRDKSNLSELKIISVLRLMFPK............................................................................... 271
14 -21.4004njg_A mol:protein length:230 7-carboxy-7-deazaguanine synthase  ali model follow..  15  42................................................................FAGCNLWSGRE-DGENGGKFKDADALVATIAGLWPAAHRFVVCTGGEPMLQLDQPLVDALHAA-------FGIAIETNGSL-------PVLESIDWICVSPKADAPLVVTKGNELKSRDLNTKLAIDWCKRHPQWRLSMQTHKYL......................................................................................................................................... 221
15 -20.2004jy8_A mol:protein length:358 FEFE-HYDROGENASE MATURASE  ali model follow..  11  16.ILEKLERREFTREVLKEALS------INDRGFNEALFKLADEIRRKYVGDEVH---IRAIIEFSNVCRKNCLYCGLRRDNKNLMTPEEIVERARLAVQFGAKTIVLQSGE---YYMPDVISDIVKEIKKMGVAVTLSL---GEWPREYYEKWKEAGADRYLLRHETANPVLHRKLRPDTSFENRLNCLLTLKELGYETGAGSMVGLPGQTIDDLVDDLLFLKEHDFDMVGIGPFIPHPDTPLANEKKGDFTLTLKMVALTRILLPD............................................................................... 272
16 -20.1004rtb_A mol:protein length:477 HydG protein  ali model follow..  12  29IVNKVNRNPKEEISQIIQKLQKGIAFANDTEELDQILFWQARKVKEEIYGKRI----LFAPLYLSNICINNCSYCSFRRENKELLSLEEAVDEAKAIREMGHTRILLVMGEEPEDKTLSYLEEIIPAIYSEVDIRRINVNI-APLTLKGYERLKKLKIGTYQLFQESYNPEVYREV-HLDGPKTNFLWRLNAVERAIEAGIDIGIGALFGLGDPLFELLGVIAHAD........................................................................................................................ 263
17 -20.1005fep_A mol:protein length:358 [FeFe] hydrogenase maturase subunit HydE  ali model follow..  11  16.ILEKLERREFTREVLKEALS------INDRGFNEALFKLADEIRRKYVGDEVH---IRAIIEFSNVCRKNCLYCGLRRDNKNLMTPEEIVERARLAVQFGAKTIVLQSGE---YXMPDVISDIVKEIKKMGVAVTLSL---GEWPREYYEKWKEAGADRYLLRHETANPVLHRKLRPDTSFENRLNCLLTLKELGYETGAGSMVGLPGQTIDDLVDDLLFLKEHDFDMVGIGPFIPHPDTPLANEKKGDFTLTLKMVALTRILLPD............................................................................... 272
18 -19.0004wcx_A mol:protein length:480 Biotin and thiamin synthesis associated  ali model follow..  40IIEKAKNLKGITPEEAAVLLNVE------DEDLLNEMFKVARYIKEEIYGNRI----IFAPLYVSNYCVNNCRYC-SNEQQRKKLTMEEVRREVEILEEMGHKRLAVEAGEDPVNCPIDYIVDVIKTIYDTKLKNGSIRVNIAATTVENYKKLKKVGIGTYVLFQETYHRPTYEYM-HPQGPKHDYDYHLTAMDRAMEAGIDVGLGVLYGLYDYKYETVAMLYHANHLEEKF-HTISVPRLRPALNISIDKFPYIVSDKDFKKLVA------------------VIRMAVPYTGMILSTREKPKFREEVISIGISQISAGSCTGVGGYHEEISKKGGSKPQFEVE. 366
19 -18.9003c8f_A mol:protein length:245 Pyruvate formate-lyase 1-activating enzyme  ali model follow..  14  18........................................................PGIRFITFFQGCLMRCLYCHNRDHGGKEVTVEDLMKEVVTFMNASGGGVTASGGEAILQAEF--VRDWFRACKKEG--IHTCLDTNGFVRYDPVIDELLEVTDLVMLDLKQMNDEIHQNLVGVSN-----HRTLEFAKYLANKNVKVWIRYVVVPSDDDDSAHRLGEFTR........................................................................................................................ 188
20 -18.3004r33_A mol:protein length:420 NosL  ali model follow..  13  51VLALAEGEEPAESRAAVALALWE------DRSIGTAELQAAAEARCGARRPRL----TFVPLYTTNYCDSECKMCSMRKGNHRLSGRKEITEQLEILHHEGVRGVGFLTGEEDKHTRLASAFRIGWAIRTALDLGFERVYFNIGSMEQDEIDVLGEDPVTMCVFQESYDRETYRRFTSVGVPKADFDRRVVSFDRWLDAGYYVNPGVLVLHDDLSAELVSLVAHGD........................................................................................................................ 283
21 -17.8002a5h_A mol:protein length:416 L-lysine 2,3-aminomutase  ali model follow..  15  112......................................................RYPDRVLLLITDMCSMYCRHCTRRRQSDDSMPMERIDKAIDYIRN-QVRDVLLSGGDALLVSD-ETLEYIIAKLREIPHVEIVRIGSRTPVITPELVNMLKKYHPWLNTHFNHPNE--------------ITEESTRACQLLADAGVPLGNQSVLLRGVNDCELVNKLVKIRVRPYYIYQCDLSLGLEHFRTPVSKGIEII........................................................................................... 312
22 -16.7001r30_A mol:protein length:369 Biotin synthase  ali model follow..  11  14YFQGSAHRPRWTLSQVTELFEKP---------LLDLLFEAQQVHRQHFDPRQV----STLLSIKTGACPEDCKYCPQSSRYKTLMEVEQVLESARKAKAAGSTRFCMGAAKNPHERDMPYLEQMVQGVKAMGLEACMTL---GTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITT-----RTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLP..................................................................................................................... 230
23 -16.5005exi_A mol:protein length:331 Lipoyl synthase  ali model follow..  12  92................................................................GDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTARDDLPDGGAWLYAATVRAIKELNPSTGVELIPDFNGEPTRLAEVFESGPEVLAHNVETVPRIFKRIRPA-----FTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGCDIVTI............................................................................................................... 260
24 -16.4004u0o_B mol:protein length:296 Lipoyl synthase 2  ali model follow..  10  1.....MALSRPLPSWLRKPLGKASEISTVQRLVRQYGIHTICEEGRCPNRGECYGQKTATFLLLGPTCTRACAFCQVEKGHAAAVDPEEPTKIAAAVATLGLRYVVLVARDDLPDQGAGQFVATMAAIRQRCPGTEIEVLSPRLSQRDCIAQIVAAQPACYNHNLETV-RRLQGPVRRGATYESSLRVLATVKEL--NPDIPTKSGLMLGLGETEAEIIETLKDLRRVGCDRLTL............................................................................................................... 237
25 -16.2005l7j_A mol:protein length:459 ELP3 family  ali model follow..  11  1.............................................MKKLSRTISGVTPVAVMTKPLPCPGKCIYCVLRAKSCEYQAYKQVALRLRIIQDMGKVELIIMGGTFLSADYQYGFIKDCYDATAQHRCVGLCIETRPDICGKAEIQRMIDGTTRVELGVQMLDDDIYKLVERGHR----VSDVAEATCLLREYGLKVHYHWMPSPEKDLALSRMVFERFCPDGLKLYPTMVVEGTILEQWWKEGRYTPYPNGTMTGLIAD................................................................................ 264
26 -16.0001olt_A mol:protein length:457 OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE  ali model follow..  17  46..................................................ARYPERPLSLYVHIP--CHKLCYFCGCNKIVTRQQHEQEIVHRAPLFAGRHVSQLHWGGGTPLNKAQISRLMKLLRENFQFNADAEISIEVDPREIELDVLDHLRAGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHAREIFTSTNIDLIYGLPKQTPESFAFTLKRVAELNPDRLSVFNYAHLPTIFAAQRKIKDAD.............................................................................................. 259
27 -15.3005l7l_A mol:protein length:446 ELP3 family, ELP3 family  ali model follow..  11  1.............................................MKKLSRTISGVTPVAVMTKPLPCPGKCIYCVLRAKSCEYQAYKQVALRLRIIQDMGKVELIIMGGTFLSADYQYGFIKDCYDATAQHRCVGLCIETRPDICGKAEIQRMIDGTTRVELGVQMLDDDIYKLVERGHR----VSDVAEATCLLREYGLKVHYHWMPSPEKDLALSRMVFERFCPDGLKLYPTMVVEGTILEQWWKEGRYTPYPNGTMTGLIAD................................................................................ 264
28 -14.2003rf9_A mol:protein length:404 Ribosomal RNA large subunit methyltransferase N  ali model follow..  11  81.....................EVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQV---CALECKFCSTQQGFNRNLRVSEIIGQVWRAAKIPITNVVMMGGEPLL--NLNNVVPAMEIMLDDFGFRRVTLSTSG--VVPALDKLGDMIDVALAISLHAPNDEIRDEINKKYNIETFLAAVRRYLEKSNANQGRVTIEYVMLDHVNDEHAHQLAELLKDTPCKI-NLIPWNPFPGAPYGRSSNSRIDRFSKVLMS................................................................................... 336
29 -14.0004fhc_A mol:protein length:368 Spore photoproduct lyase  ali model follow..  10  105.............................................................IPLATGCMGHCHYCYLQTTLGSKVNLDDIAQAQKYINERAPEITRFEAADIVGIDHLTHSLKKAIEFIGATDYGRLRFVTKYEHV-DHLLDARHNGKTRFRFSINS-----RYVINHFEPGTSSFDGRLAAARKVAGAGYKLGFVVIYRHEGWERGYFELFQEL......................................................................................................................... 274
30 -12.5003can_A mol:protein length:182 Pyruvate-formate lyase-activating enzyme  ali model follow..  14  7........................................................................................................VTFCGGEPLLHPEF--LIDILKRCGQQG--IHRAVDTTL-LARKETVDEVMRNCELLLIDLKSMDSTVHQTFCDVPN-----ELILKNIRRVAEADFPYYIRIPLIENADEKNIKLSAEFLASLPRHPEIINLLPYHDIGKGKPKGYKMQTPSEEVQQQCIQILTD............................................................................ 173
31 -12.5004jc0_A mol:protein length:438 Ribosomal protein S12 methylthiotransferase RimO  ali model follow..  16  135......................................................EERPYAYVKISDGCDRGCTFCSSFKGSLRSRSIEDITREVEDLLKEGKKEIILVAGIDL--YRKQALPDLLRRLNSLNGEFWIRVMLHPDHLTEEIISAMLELVKYFDVPVQHGSDKILKLMGRTKSSEELKKMLSSIRERFPDAVLRTSI-IVGFPGETEEDFEELKQFVEEIQFKLGAFVYSDEEGTVAFNLKEKVDPEMAKRRQEELLLLQAEISNSRLDRFVGKKLKFLVEGKEGKFL.................................................. 386
32 -11.2006fd2_B mol:protein length:457 Putative apramycin biosynthetic oxidoreductase 4  ali model follow..  11  197..........................................................ITSINGSFGCPYPCRFYCPYPRKIRTYPVERIVAEFRQCAELGITAAVFR--DPVFSFHRDRTLELCQALKAADTGVPWWCETRIDRLDEEVVAALVAGCVGVEVGVESGDPDMQATAVRKR----NLDTVRKFHAVARKAGLKLVFLFLILPRETRMSIRRTFDFIL........................................................................................................................ 365

FFAS is supported by the NIH grant R01-GM087218-01
1 3 7 7 9 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Sikora S, Godzik A. Combination of multiple alignment analysis and surface mapping paves a way for a detailed pathway reconstruction--the case of VHL (von Hippel-Lindau) protein and angiogenesis regulatory pathway. Protein Sci. 2004 Mar;13(3):786-96. Epub 2004 Feb 06.