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Query: sp|O14791|APOL1_HUMAN(removed signalp:1-27) Apolipoprotein L1 OS=Homo sapiens GN=APOL1 PE=1 SV=5, from H.sapiens

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst EEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTMDPESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEEKLNILNNNYKILQADQELLast
1 -75.000PF05461.11; M3YMB0_MUSPF/26-333; Apolipoprotein L  ali follow..  38  1..................................................TVRREELDTLLSDQESWERFVAEATLSREEAEALREVLNELQRTM-----DMEADEQEARESFLHQFPELKLKLEERIRKLHELADEVDRVHRDCTIANVVANSTGVVSGLLSILGLGLAPVTAGASLALLATGMGLGVAATVTQVSTSLVEDSSESSAKAQASHLTSTDFDKGEVIAKVLHDRIPQIYSLTGTCFRALQNIANNVRAINLAKVKPRLVVNARR--LMTSQRISVRGGRQVQKAFGGTALAMTKGARIMGAVTAGLSLAMDVVNLVKDSEHLQKGAKTESAEDIRQQARELESKLKKLSEIYEIL...... 308
2 -8.600PF15984.5; Q8XQX4_RALSO/108-304; Bacterial collagen, middle region  ali follow..  9  1..................................................................................................................................................LPLVPSSAQSGLGGVVENLGATVSALGAGVQDGLGSIGSNPNPIGTTVASTGNVVTGVGNT-----VTSAGTLVGGLGTGQLSPLAPVTTPLAGALTQVGQAVTNAGTTLGTTLSTGPVEQLTQ--QLSTAIVPLTSQIIGGTQTVGATTGMGTPANSLLGTLGGAIANGG---TLTNANVPVVSNVGGVVGAVGNTVASLGGVAY................... 197
3 -7.850PF05802.11; C5B9R0_EDWI9/34-192; Enterobacterial EspB protein  ali follow..  14  8.....................................................................................................QLGELFGKLRDVLRQYQQAQQSNKMQKTAFETRVDSIDKDFQ----AKQAQAVAQIVGGIAQTVGGGFGEHTISTGLNNMTQGIVGVGYANDLTRQSQEEQALYQHGMADQLLKRAEETKEKALKVSGDLREILATLTQAHEHLSSSVR......................................................................................................................... 158
4 -7.450PF13168.6; Q9Q8U4_RFVKA/922-1114; Poxvirus B22R protein C-terminal  ali follow..  16  1................................................................................................................................................LVIVNLLSSVLSQIGGTISITGS--------NSPTVAVAGLALQGISGLIDAATSIYHILTGSQPYKDAIEKFSNYANYMSRTEA.............................................................................................................................................. 78
5 -6.740PF15475.6; H3CAE9_TETNG/29-118; Transmembrane protein C12orf23, UPF0444 topsan  ali follow..  16  18..................................................................................................................................................LFSVTKGVVGAVGGVAWVGGRSLE-ITKSAVTTVPLMGVGLAVAGGVSTVGSSVAGKLPFTAKKDKA.............................................................................................................................................................. 90
6 -6.590PF02009.16; Q8I2C8_PLAF7/31-368; Rifin  ali follow..  11  12....................................................................ELYSPTNYDSDEMKRVMQQFEDRTTQRFHEYDEKMQSKRIQCKD-IILKDKLDKELTEKFATLKSLADKVEKLKCTQNLGGIVAPSSGVLGGIGEFE-AALAAAKEFAEKAGAAQGAIAGNAHGMKIVIYYLKDWGIQQCCPEIFNPFVAEVANISGDIIAKYSAKCADTVTGGNSMCKAFCLKLGTNIAHGGRTLSVDHIVQLKIKGLVERADQAVAHVTKTTSETVTAAIKARETALIEGRNASIIAIIVIVLILVIIYLILRYRRKKKMKKKLQ--LKLLKE.................. 338
7 -6.430PF16013.5; B5DR01_DROPS/112-408; Domain of unknown function (DUF4781 topsan)  ali follow..  6  72......................................................................................................................................TPASGARHRILNVGDKVATVGSLVASVPVAAALA-----VPVGGPIILAATAVGVATAAYSTLRSANRLYDRVRHGQSTS---EARGQWLGVAGGVVGLGATGATRLMSRVAAAGTEVNCAAQFAVKGINVSSI--VISGTGVANGVYDLYLKVGDDQTLSKLDILQIASSLVIFTHSINNLRIASKVSNRPTLMRALRNQTRKVVRQISQESIKLHNGSDSGKFDIVRTFN..... 297
8 -6.260PF05844.12; O68699_YERPE/13-306; YopD protein  ali follow..  8  95..........................................................................................................................ENKATITAQKEQVAEMVSGAKLMIAMAVVSGIMAATSTVASAFSIAKEVKIVKQEQILNAFNAATQPLGQMANSAIQVHQGYSQAEVKSIAANEKQKAEEAMNYNDNFMKDVLRLIEQYVSSHTHAMKAAFGVV................................................................................................................... 294
9 -5.990PF01723.16; CHBE4_BOMMO/1-191; Chorion protein  ali follow..  14  88...................................................................................................................................................TGLGIASENVYEGSVGVCGNL--PFLGTADVEFPTAGLGGIDYTCGDGAVGITVENA....................................................................................................................................................................... 144
10 -5.960PF00731.20; R5S1S7_9BACE/2-149; AIR carboxylase  ali follow..  9  8...............................................................................................STSDYEVMSGAEEMLKALDIPFEKRVVSAHRTPDLMYEYAKTAKARGISVIIA-GAGGAAHLPG---MVAAMTTLPVIG-LSIVQMPGGVPVATVAINGAKNAALIAASILALQDEGVSARLEKFRQEQTD................................................................................................................................................. 147
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 9 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Jaroszewski L, Li W, Godzik A. A segment alignment approach to protein comparison. Bioinformatics. 2003 Apr 12;19(6):742-9.