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Query: sp|P11766|ADHX_HUMAN Alcohol dehydrogenase class-3 OS=Homo sapiens GN=ADH5 PE=1 SV=4, from H.sapiens

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECINPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFELMHSGKSIRTVVKILast
1 -35.400PF08240.12; A9CHB7_AGRFC/24-130; Alcohol dehydrogenase GroES-like domain  ali follow..  37  1...............................EGEVLVRIRRIGVCGTDLHIFTGNQPYLSYPRIMGHELSGTVEEAPA-GSHLSAGDVVTIIPYMSCGKCNACLKGKSNCCRNIGVL---GVHRDG------------------GMVEYLSVPQQFVLKA...................................................................................................................................................................................................................... 107
2 -27.500PF00107.26; ADH_SULSO/182-311; Zinc-binding dehydrogenase  ali follow..  21  1.........................................................................................................................................................................................................GLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRAGADYVINASM-QDPLAEIRRITESKGVDAVIDLNNSEKTLSVYPKALAKQGKY-VMVGLFGADLHYHAPLI-TLSEIQFVGSLVGNQSDFLGIMRLAE......................................... 129
3 -22.900PF16912.5; I7BJ28_NATSJ/144-370; Glucose dehydrogenase C-terminus  ali follow..  13  21.....................................................................................................................................................................................RATRSAFDWQPASALVLGTGSLGLLTAAMLTETLEYDRVYCDRPHPTIDIVDRLGATYIDSRET-----PVSEIPAAYEPMDLVYEATGYAKHAFEAIEALAPNGVAALLGVPEDWAFEVDGGHLHVLSNKALVGSVNSNRGHFEAAIDTLS--ALPDWVLTEVVSGVYDLAALERAFPEVTAPVAATGGSTV 213
4 -16.000PF13602.6; B7KCY1_CYAP7/190-331; Zinc-binding dehydrogenase  ali follow..  14  1..........................................................................................................................................................................................................................................FGADYPILYTQ-TDFSAAALEWTEGKGVDVAFDTVG-GKTFFDTVPAVRVYGDLVTILEPDGSKGTLKVASLELMLTPALMGLREAQEHQTEILSQCGTWIDEGKLNI--HLSQTYPLADAVEAHKQVETGSTTGKVAL. 142
5 -9.310PF14537.6; D4H4F3_DENA2/139-220; Cytochrome c3  ali follow..  14  1.....................................RHAKAEVCHGI-ALPEFASEVSNVTCLGCHGELKALQKKTESAEHKDMNPHKSHLGDIACTVCHHIHTEQTAYCVN..................................................................................................................................................................................................................................................................... 79
6 -8.380PF13847.6; B2J9C6_NOSP7/55-253; Methyltransferase domain  ali follow..  13  3..............................................................................................................................................................................................KEKVILDAGCGT-GYKSLVLAEANPGAKIVGIDISEESIKLAQQRLEHHGFDNAEFHVLPIQELPK-----LNYQFDYIDLAAALQGMISVLKPNGIIRSNL.................................................................................. 108
7 -8.130PF03059.16; A3DUI9_MALBX/3-277; Nicotianamine synthase protein  ali follow..  11  109.....................................................................................................................................................................................NILSQHFTRMPIKIAFVGSGPLPLTSIVLASNHLTKSFDNYDINASANSKALGLVSSDPDLSKRMVFHTTDIMDVTALKDYEIVFLAA-KLKIIDHLAKYMAPGATLML.................................................................................... 226
8 -8.070PF01135.19; PIMT_CAEEL/8-220; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)  ali follow..  13  1..................................................................................................................................STNSELIDNLRNNRVFASQRAYD--AMKSVDRGDFAPRAPYEDAPQRIGYNATVSANHLVAGAKALDVGSGSGYLTVCMAMMVGRNGTVVGIEHMPQLVELSEK------IRKHHSEQLERGNVIIIEGDGYNAIHVGAASKGVPKALTDQLAEGGRMMIPVEQVDGNQVF......................................................................... 185
9 -8.050PF00670.21; SAHH_DICDI/191-351; S-adenosyl-L-homocysteine hydrolase, NAD binding domain  ali follow..  15  2..............................................................................................................................................................................LYGCRESLIDGIKRATDGKVAVVAGYGDVGKGCAQSLSKMGA-RVLVTEIDPINALQACMDG----YQIVTMETAAPL---------SNIFVTTTGCRDIVRGEHFAVMKEDAIVCNIGHFDCEIDVAW....................................................................... 120
10 -7.410PF08704.10; Q6DFS3_XENTR/64-300; tRNA methyltransferase complex GCD14 subunit  ali follow..  16  25...............................................................................................................................................................................YSTDISLITMMLELKPGSVVCESGTGSGSLSHAIIRTVAPTGHLYTVEFHQQRAEKAIEHKVDHLVTVKNQDVCKHGFGVTGIADAV--FLDIPSPWEAIGHAKSAMKSEGGRICS................................................................................... 142

FFAS is supported by the NIH grant R01-GM087218-01
1 3 9 6 1 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ginalski K, Godzik A, Rychlewski L. Novel SARS unique AdoMet-dependent methyltransferase. Cell Cycle. 2006 Oct;5(20):2414-6. Epub 2006 Oct 16.