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Query: sp|P61221|ABCE1_HUMAN ATP-binding cassette sub-family E member 1 OS=Homo sapiens GN=ABCE1 PE=1 SV=1, from H.sapiens

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAAKGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDDLast
1 -31.700PF00005.27; YTFR_ECOLI/25-174; ABC transporter  ali follow..  19  8...................................................................................................LRRGEIMALLGENGAGKSTLIKALTGVYHADRGTIWLEGQAISPKNTAH--AQQLGIGTVYQE-VNLLPNMSVADNLFIGREPKRFGLLRRKEMEKRATELMASYGFSLDVREPLNRFSVAMQQIVAICRAIDLSAKVLILDEPTA.................................................................................................................................................................................................................................................................................................................................................................. 150
2 -23.500PF09818.9; Q10V01_TRIEI/4-493; Predicted ATPase of the ABC class  ali follow..  1...................................................................................................................QQTLRKKLLDLDNANYKAYR------DIQGSYQFSDFTLIIDYVQGDPFAA--PSKLRVQLPYTVSGFPPELYKTPIREMALRDFLTR-KFDRMAYEVSGRRGTGKSGMIAIGQEVLERTSVYLIKLAPPGVEVRLVVGLPAGGRRILGRQAAEMLVHRTLKYEQLDADVCRRHVETVEDTDWLRKQLPEKNLVAFVANGAILPRRSGVDDRPLSSEEVVPFKSPPSLEV----------EFECPNQGKISGMGIPKGVTLIVGGGYHGKSTLLKAIEGGVYNHVPDVTDPAAIKIRAEDGRSVAGVDISPFINQLPQNR---STTQFTTENASGSTSQAANIMEALEAGLGNSNLEETTTTATTPVFLVDEDTAATNFMIRDRFIDKVRQLYTDYQVSTILVMGGSGDYFEIADKIIAMENFQAQEVTE...................................................... 463
3 -17.900PF13401.6; B2UJB3_RALPJ/42-210; AAA domain  ali follow..  16  2.................................................................................................................................................................................................................................................................................................................................................................................SQESILLVCGPTGAGKTTLAKFMVENAHSQSHGVIPAIYVQAPASGETKFSWRLFYQRILNQLGDDL-DSPKVAYGVDSLSGRLVRPRGTSGNSLAALRTAVERGLRARQVQFMVIDEAAHIFRDTQREVQLDTLKSLVNECGTQIVLVSYDLYHL.......................................................................... 168
4 -13.700PF13166.6; Q63PW4_BURPS/9-780; AAA domain  ali follow..  14  25......................................................................................................KKMNVIYGRNYSGKTTLSRIIRSLETGSISPRYASPSFSITISGSKNKEIEVEIDKLEDELGSVENKTGLRHSYQEKKKAHADKKKAAQDAQDELDKKIFKLDIKTVQDKKIAPLDDADRSSKVKLLSEVALPDIEKRLSFNSSLP-ALAKSTVELITKKIKPSAPIQELLNDAILQNWVKSGIPLHEGSPLPADLWKRLGDHFNQESQDLEKDLDSVLTKISNEKTRIKNVVTVDRKNFYSANQATFDNLKADLDDAELNARKKDIFTERSTIDVQDNTVSISQKVSLVNELIERNNKTTITKAKDELDAVEAEGKKRVDRVKELRTQLRDEKRGAEQVNQYLGHFLGHGGLDQAAYNLSEGECSLVAFCYFLAKKKLIIYIDDPISSLDSNHIFFVFSLIENYITKPIEDLFISTHNLEFLKYLKR..................................................................... 631
5 -12.800PF05621.11; B7J739_ACIF2/21-211; Bacterial TniB protein  ali follow..  11  34..................................................................................................................................................................................................................................................................................................................................................................................RMPNLLIVGDSNNGKTTVIRRFQKLHGEGVNE------------------DAEPVPVIVSEAPPSADEKGLYIAILERFWTPYRATDSASKL-----RYQVVHLMRDCHVRILVIDEFHSLLTGTVTREVMNAIKLLCNELAIPIVGV................................................................................. 160
6 -12.700PF07652.14; Q32ZD8_9FLAV/1675-1822; Flavivirus DEAD domain  ali follow..  14  1................................................................................................................................................................................................................................................................................................................................................................................FKKKQLIVLDPHPGAGKTRKV------------PEFIRQAVERRLWTLALAPTRVVAAEMAEALNGL------VRYLTPAVIQQHTGKEIVDLMCHATFTMRLLSGGRVPNYNMFIMDE--AHFTDPSSIAARGYISTKVDMGEASAVFMT................................................................................ 133
7 -12.300PF13558.6; B3PE30_CELJU/966-1055; Putative exonuclease SbcCD, C subunit  ali follow..  15  1.............................................................................................................................................................................................................................................................................................................................................................................................................................................SPLNDHRRFFSYDVEIFTQNKSIGLLSKRLGPGSGGEHRTVIFGAALAAGGGIMLLDEAFEKMDAQNVRATADYLNA............................................................................................. 90
8 -12.100PF10443.9; C8VEZ9_EMENI/373-791; RNA12 protein  ali follow..  11  7............................................................................................QLNSWLTESAETFIVIHGPRGSGKRELVLDRTLKDNKYKLIIDCKQIQDAKGDTAKIARAASQVGYRPVFSMNSISSFIDLAAQGMIGTKAGFSETLDAQLSNIWQNTAVALKSITLEHRKKTDPDAQLSDEEYLEAHPEVRPVVVIDNHNNPEATSVVYDKITEWAAGLATGNIHVIFLTTDVSFAKPLSKALPNTVFRTISLGDCSL-----------------------------------EVGRKFVLNHLEHEARNKNKDTRHEEDLAELD----SCIGVLG----GRLTDLEFMAHRIEAGETPRGAVTRIESESQKWTHQQAWHLIKTLARSKDGSVPYNHVIQSDLNSQALRELEQAELISIVNGSPERVRAGRPVYQAVFKRLTENKSSRLD-------MEVLSQLISKENKSIGKYEEELLLLGKL....................................................................... 419
9 -11.600PF07088.11; GVPD1_HALSA/23-536; GvpD gas vesicle protein  ali follow..  11  1.............................................................................................LSQFFMGDAGETLLINGAPGTGKTLFTIRGLDVLDRD----------------------SDVLYVSTRVDQETVHEMYFADHSSLDTTAILDLFQDPFELPLDVDVPFEKLDLDSLLEWIQEINA-------------ATTQLTIAFDSWELIYEYDIKTVTNQLAVLAREENIRLMLVTEAPSSLEYIVDGVVTLQVKEDDRGRTRRDLRLDKLRGVRIGNRLQPFTLADGQFQVPVELLTIQTGTGNGTWDPLANSKAKFSTGIRDLDRISGGYNRGSVVHLDLGPDLSRDAWLPTIRNFLSQEMGVAVVPPREGSPGLLHNDLNTVLSSQVFDTYCHGADDGSRSTDGVTGSDQPHPIDEDFESPIEGGQLA-AYVEQVREESEDPLLHVISMDTAQEAFETRLGDFANYVALHNDLTLLITKQGTELADRVADMHFRLERSGDAIILYG..................................................... 487
10 -11.400PF13175.6; I1YS32_PREI7/1-378; AAA ATPase domain  ali follow..  12  6.....................................................................LKLKNFR-SYRSVEISF----------------ENLTAFIGRNDIGKSTILEALDIFFNEGKGVVKLEANDSDRKNSDNDSEVQDPLKEATKEIISSSNLETQFNQIATEVTKKLREVANSEVKDLKWAELFKSVSIEGNDGIAMNKRGSGVRRLILLNFFRANRTLIYAIEEPETSQHNEHQKILIDALKNLANNGRQIMLTTHSGNIV................................................................................................................................................................................................................................................................................................................................ 378
11 -11.000PF13304.6; A0ZCH2_NODSP/23-347; AAA domain, putative AbiEii toxin, Type IV TA system  ali follow..  1........................................................................................................VTLLIGNNNSGKSNLLTGIQHFCRLVRRGRPGNINKTVNVHRDLYPHRYRLAADNEPMGFIITWNNLKGSIIYEMELYENRHFPESASCKEKITIRLDSADEKIITSGHDQSTNLMALRQDLEDNASLQTAEKQLCKEFFGDFANTYSYHFQPAFLKGLVKDEQMGNLDDAPHEIGKSDYI---------------------------------------------------------------------------------------KIPAELGSTGLGLQAVVKYIKEKEERTFTRFTALMRRFENNFQGVRYNEKISKLVWEFDFGRKTTVEEF----------------TPDSVSDGFMKAAAISLLASLPPSLILLEEIENGVNPGNIQELMHWIWQMTSPTSSQFIITSHSPSVLR......................................................................... 325
12 -10.800PF13481.6; B2JV40_PARP8/220-401; AAA domain  ali follow..  12  23............................................................................................................................................................................................................................................................................................................................................................................VDDVIPAHAVGAVWGASAAAKSFLVLDLAAALT--ECRSFFGHDVFEPVPVLLVSLEG------NNGLPRRYLAWEKHNGRPVPARLHTLTQGFSLLDPRDTDDLCEAIETCGITGGVVFIDPFALATSSADMGRAGAALNTLRERTGCTVIAVHH............................................................................... 176
13 -10.800PF13521.6; A4CIV1_ROBBH/14-173; AAA domain  ali follow..  16  2......................................................................................................................................................................................................................................................................................................................................................................................VVLFGPESTGKTTLARELARHYGPEYAREYLQEKWDRVQQTCAPE---DLLPIARGQMRLENIGAREASRLL-------ICDTDLLEYYGGGCDPKLQAAALANDYDLYFLTDIDIPWKPHERAEMFHYFKTALRENNRRFVILSGGRE............................................................................ 158
14 -10.700PF07931.12; Q98FG2_RHILO/59-238; Chloramphenicol phosphotransferase-like protein  ali follow..  11  1......................................................................................................ARIVLLNGVGSAGKSSIARALQTITAAPFLHVQMD-SFLEMLPDALQDHADGFSYETVRQDGKPAVVIRAGPVGERTLRGMRHAIAAMAGQGNDL--IVDDVLCNGELSDCVDLLSAFDFHLVGV------MAPLEVLEAREARRADRLPGLARWQYERVHAGISYDLEVDTSQSTPLECARRIQ........................................................................................................................................................................................................................................................................................................................ 176
15 -10.700PF18751.1; S5Y5G5_9CAUD/1-187; P-loop Nucleotide Kinase3  ali follow..  15  2..................................................................................................................................................................................................................................................................................................................................................................................TARLIYLVGQPGSGKSTLMSALTAGFDRHK--IAPAPDYPVAHDVLADKTTGEVVGAELGVRRELFSGTDALPSSIIDKAAPWVRSQPYPLLEGARRRFIDAALEGGYEVTLVLLNDAEDWRWVKGRLSASRNLADALSGPAYEGKAVEVLRGHPDPIRSILKGIDA.............................................................. 187
16 -10.400PF02456.15; PKG1_ADEG1/61-425; Adenovirus IVa2 protein  ali follow..  14  71.....................................................................................................................................................................................................................................................................................................................................................................QHGQLPSINMGK-QPIIGVIYGPTGSGKSHLLRALISMLDPIPETVIFEKNMIPPIEQTSWNLQLVEANFDCREDGTIAPKTSTFRPEFMEMTYEEATAPE--HLNIDHPDNI-YVKVSKRGPVAIIMDECMDKLCSGSSVSVLKLFARSAHCTAFYIFVVLHNMAPRTAIGNVPTLKVNAKMHILSCHIPQFQFA.............................................. 273
17 -10.200PF06745.13; O29463_ARCFU/20-274; KaiC  ali follow..  12  23..........................................................................................................................................................................................................................................................................................................................................................................RKPLGGIPHLAVMNITGVPDTGKSLLAEQFA------------ITQAGSGYRVLYVTVESPANFLYTAMKERSEAMGVDFTKVESNVVVIDASESDELRENPKALMETMAYAIKEKKVTNTIIDSITGLYKEMMARQIVRQFFNFMKKYRQTGIFVSQGGLAVAHIVDGTIVLD............................................................... 199
18 -10.100PF11398.8; Q6LIW4_PHOPR/1-374; Protein of unknown function (DUF2813 topsan)  ali follow..  10  16.............................................................................................................................................................................................................................................................................................................................................................................RLSLSFNQLSVLIGENAWGKSSLLDALSIALAVNTEFYTFKFSDFHVDYALGHDKQTNIQIVLHDEQAKKLRIERRLDNTCRRLELKSSVNALRTLVDSKQSRLVLMGLLNAISRPIMILEDPEGRLHPTVLHQAWTFVDSMPMQ----KILTTNSPDLLSIVLGSIKKLIRQPDRTQVFALNKNALSRDEERRISFHVRLHRPSA............................ 374
19 -9.990PF00485.18; KPPR_SYNY3/10-192; Phosphoribulokinase / Uridine kinase family  ali follow..  13  1.....................................................................................................................................................................................................................................................................................................................................................................................LIGVAGDSGCGKSTFLRRLTDLFGEEFMTVICLDDYHSLDRQGRKAAGVTALD-------PRANNFDLMYEQIKTLKSGQSIMKPIYNHETGLLDP----PEKVEPNKVVVIEDFGVYLDISEEVKINWKIQRDMAERGHTYEDILASINARKPDFTAYIEPQKQYADVVIQVLPTRLIE.............................................. 183
20 -9.940PF01637.18; A8M939_CALMQ/15-228; ATPase domain predominantly from Archaea  ali follow..  5......................................................................................................................................................................................................................................................................................................................................................................EVAIRQIEKLAEKGNPVVIYGPEGCGKSAFLKQAVEVLGEYDYSVVKV-------------------SPLEDESNEKLRYSEELRGLFRDIRIPTPFNDASALIDIAISLLYDVVRRRIRRKIALLADDVFQAIGLDKAELLVKRLLNMVDYERIVVIVATSEGVTWGRIGRH.................................................................... 167
21 -9.900PF03266.15; NTPTH_METAC/3-167; NTPase  ali follow..  14  2......................................................................................................................................................................................................................................................................................................................................................................................IAVTGSPGVGKSTVVAKTAEKLAEKPGFKI-----------GGIRTAEIRKEGHREGFSIRDLATGKTGILSHVKGSGPRLGKYHVNLDDLERIGANAVRN-ALACDLVVIDE-IGPMELISQ-SFVSAVEEVLESDKPVLAVLHHSSPLAQRFRKGFEVLT............................................................... 151
22 -9.800PF03215.15; RAD24_YEAST/58-237; Rad17 P-loop domain  ali follow..  12  35.........................................................................................................................................................................................................................................................................................................................................................................LDAMFLPNAKHRILLLSGPSGCSKSTVIKELSKIL-----------------KYRQNSNGTSFRSTPNEHKVTEFRGDCIVNDLPQMESFSEFLKGARYLVMSNLS--------------LILIEDLPNVFHIDTRRRFQQLILQWLYSSEPLLVICITECE............................................................................ 170
23 -9.720PF13555.6; Q0A6A1_ALKEH/19-80; P-loop containing region of AAA domain  ali follow..  30  22.....................................................................................................GGDNSLLTGDIGSGKSTLVDAITTLLVPAQ.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 51
24 -9.680PF13245.6; B1YJE6_EXIS2/332-475; AAA domain  ali follow..  17  10..................................................................................................................................................................................................................................................................................................................................................................................KAPLMVLTGGPGTGKTTVIKGILHALQEIHDWPLEKSQVKSGEVY---------------PYVLVAPTGRAAKRLSEATDVPA---MTIHRLLKYDGTNFQLDEDQPIAGKVLIIDE-SSMIDIYLLSSLLRAVPN------GMKILFVGDRDQLPSV....................................................................... 142
25 -9.420PF01695.17; Y4IQ_SINFN/60-238; IstB-like ATP binding protein  ali follow..  14  37........................................................................................................................................................................................................................................................................................................................................................................AIAAGDSWLAKGANILLFGPPGGGKSHLAAAI-GLALIENGWRVL-----------------------------------RTTDLVQKLQVARRELQLESAIA-------------LDKFDLLILDD--VTKDQAETSVLFELISA--RYERRSIMITANDPAMTLAAVDRLV.................................................................. 173
26 -9.290PF18748.1; A0A0A0YSQ1_9CAUD/11-206; P-loop Nucleotide Kinase1  ali follow..  10  15.................................................................................................................................................................................................................................................................................................................................................................................ARGELFYVKACNGAGKSTIPSYCAERDPEAY--------------------------VSQDGRILLTVMPSYGMLAFGKYDKSKSKGVDSLKDYDEMKKAVELSELEEFIGYTAFFE---GVIPSTILHTWVEYLNRPARPLTTVFIDTDLET-CLSRVNSR.................................................................... 147
27 -9.280PF07475.12; HPRK1_OCEIH/130-300; HPr Serine kinase C-terminal domain  ali follow..  11  1.................................................................................................................................................................................................................................................................................................................................................................SKFAPFTAIHGVLVDI-YGVGVLIIGQSGVGKSETALELV-----KRGHRLVADDNVEIRQEDYDSLIGNAPPLIEHLLEIRGLGIINVMTLFGAGSVRSLVINLENWDEKKQYDRLGLDEDMM---KVMDVHLPKATVPVRPGRNLAVIIEVAAMNF----RLKRMGVNTAEEFSERL................................................................... 171
28 -9.230PF13238.6; A0B5Y2_METTP/3-117; AAA domain  ali follow..  42  1......................................................................................................................................................................................................................................................................................................................................................................................IALTGTPGTGKTTVSGLLP.............................................................................................................................................................................................................. 19
29 -9.080PF04665.12; Q6TUP8_YMTV5/6-246; Poxvirus A32 protein  ali follow..  11  16......................................................................................................................................................................................................................................................................................................................................................................................IALVGGSGSGKTAYLLSLFNTFVEKYRHIF-----------------------LFTPVYNSEYDSYIWPDHVNRVTTYEELDYSLITTKQKIEKYVKKQGNDKTTEMFLLILD-----DMGDKQIRSSCLLDFLRHLNTSIILLCQTYKNGRTSITHFCCCNVSDSDIENMLRSMSITGSKKDLLKSVSLMRSVSVNKRRVIIIEDSVFSEGEQRVCYDTADDD. 218

FFAS is supported by the NIH grant R01-GM087218-01
1 3 6 9 2 4   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Shiryaev SA, Ratnikov BI, Chekanov AV, Sikora S, Rozanov DV, Godzik A,Wang J, Smith JW, Huang Z, Lindberg I, Samuel MA, Diamond MS, Strongin AY. Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase. Biochem J. 2006 Jan 15;393(Pt 2):503-11.