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Query: sp|Q5VV42|CDKAL_HUMAN CDK5 regulatory subunit-associated protein 1-like 1 OS=Homo sapiens GN=CDKAL1 PE=1 SV=1, from H.sapiens

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTIPGIQKIWIRTWGCSHNNSDGEYMAGQLAAYGYKITENASDADLWLLNSCTVKNPAEDHFRNSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQIDRVVEVVEETIKGHSVRLLGQKKDNGRRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGNLASYPIDELVDRAKQSFQEGVCEIWLTSEDTGAYGRDIGTNLPTLLWKLVEVIPEGAMLRLGMTNPPYILEHLEEMAKILNHPRVYAFLHIPVQSASDSVLMEMKREYCVADFKRVVDFLKEKVPGITIATDIICGFPGETDQDFQETVKLVEEYKFPSLFINQFYPRPGTPAAKMEQVPAQVKKQRTKDLSRVFHSYSPYDHKIGERQQVLVTEESFDSKFYVAHNQFYEQVLVPKNPAFMGKMVEVDIYESGKHFMKGQPVSDAKVYTPSISKPLAKGEVSGLTKDFRNGLGNQLSSGSHTSAASQCDSASSRMVLPMPRLHQDCALRMSVGLALLGLLFAFFVKVYNLast
1 -74.800PF04055.21; CDKAL_HUMAN/208-381; Radical SAM superfamily  ali follow..  100  1...............................................................................................................................................................................................................ISINTGCLNACTYCKTKHARGNLASYPIDELVDRAKQSFQEGVCEIWLTSEDTGAYGRDIGTNLPTLLWKLVEVIPEGAMLRLGMTNPPYILEHLEEMAKILNHPRVYAFLHIPVQSASDSVLMEMKREYCVADFKRVVDFLKEKVPGITIATDIICGFPGETDQDFQETVKLV...................................................................................................................................................................................................... 174
2 -33.500PF00919.20; MIAB_PROA2/4-103; Uncharacterized protein family UPF0004 topsan  ali follow..  31  1................................................................KVSIRTFGCQMNQADTEIISSLLTAEGYCLVAEEDDADLVMLNTCAVRENAVEKIMHHLDSLKGLRRRVGVIGCVPQYYREEMFGVIDFIAG....................................................................................................................................................................................................................................................................................................................................................................................................................................... 100
3 -14.500PF01938.20; CK5P1_DROME/494-568; TRAM domain  ali follow..  27  1..............................................................................................................................................................................................................................................................................................................................................................................................................................................RKMEGQEQLILIEGKSKRSAHWFGRNDANIKVIVPSIYVGVGDFLAVRIEESNSQVLKGTPL....................................................................................... 75
4 -10.100PF18693.1; R5H407_9FIRM/388-458; TRAM domain  ali follow..  16  1.................................................................................................................................................................................................................................................................................................................................................................................................................................................IGSTDEVVVEGYDKYLGLYFGRSAMFAPEI-GAKKPRIGDFVTVRFDDVVDNNLLGEMV....................................................................................... 71
5 -9.150PF13394.6; B8DWG8_BIFA0/78-188; 4Fe-4S single cluster domain  ali follow..  14  3...................................................................................................................................................................................................................SGCPFHCVECYNSSIWDFQAGHNDKLEAQIMDDLAQSFVQGITFLG------------------------------------EPLLNTGVLLPLARKIR------------ERFGHTKDIWCWTGYTWEELMRDGETQDKL--DLLHEIDILV....................................................................................................................................................................................................................... 108
6 -7.010PF13353.6; D1BLW3_VEIPT/12-149; 4Fe-4S single cluster domain  ali follow..  13  2........................................................................................................................................................................................................NGEGIRTSIFVTGCTHCCYNCFNEEYQDFNAGKTQAETDLVVSYVKNPTCSGLTLLG------GEPFQN--VQGLLPVVRAVRAAAPKKKIWAYSGY---EIDDILEDELRSALLQEIDILVDGRFVDELKDPALRFRGSSNQRII......................................................................................................................................................................................................................................... 138
7 -6.750PF08497.10; H8GQS3_METAL/29-377; Radical SAM N-terminal  ali follow..  40..................................................................VLEAQGFRVGIISGGNMDSMVNRYTSDKKIRSNDAYTPDGAAGKRPDRAVSVYSHRCREAFK-EVPIIIGGIEASLRRIAHYSKADLLVYGNAERQIVEIAHRLARGEALSEITGIRGTAYFVKEIPEGFAVKDSTEVAETVPGENVVQFDKTLLRNRRANTVIRLPAYEDVKDDPVLYAHA----------------RVMHGETNPGNARPLIQQHGQRQVWINPPPIPLTTKEMDGVFGL----PYSRLPHRTYGNANIPAFEMIQHS................................................................................................................................................................................................................................................... 349
8 -6.600PF01446.17; A0A0C1NIB9_9CYAN/69-306; Replication protein  ali follow..  11  10.....................................................................................................................................................................................................................CRVHCPVC--QWRRALMWKAKAYKILPQVVADYPKYWLFITLTVKNCQ------IWELRTTLDGINKAFKRLTELKAWSSAKGWV--KSVEVTKGRDGMSAHPHLH---------ILAMVQPSYFSYGYLAKWVKLWQQCLDTDYEPIVHISAIAKQHDPTILIPEILKYQT---------ESDLIADREWFLELTRQLHKTRAIAIGGVLRHYMRELE................................................................................................................................................... 205
9 -6.100PF10459.9; E3FSI6_STIAD/18-681; Peptidase S46  ali follow..  12  18....................................................................AQYGFEPTAQWLDKVLSSARIAGGCSASFVSANGLVMTN-CT---------RGCIEQLSTADKDYIANGFYAKAPTDEL-------MEINQLAEITDVTDRLNTATQGRTGKEYSDTLKAEMAKIEKECATSDQVRCDVVTLYQG-----KYNLYKYRR----------------------FQDVRLVFHAIAFFGGDPD----------------------NFEFPRYDLD--VSFVRVYQDGK-------PAPQ--DNFFKWSKAGAKEGELT------------------FVSGHPGRTSR-GLTIAELEYQRDVVLPKTLMLMSEQRGLITEFQKRGPEQKRISNNLLFGVENAVKAQKGRHALLDKAFFAQKVAAEQEL............................................................................................................................... 317
10 -5.830PF01026.21; Y454_HAEIN/4-256; TatD related DNase  ali follow..  10  3..........................................................................................................................................................................................................................SHCHLDALDYENLHKNISDVVEKAH---ARDVKHLLAIGVTLSRFEQAY--DSLREFNNVSLAC----------VHPLDFEEDAERLLRLAQDPKVIA------EIGLDYYYSADNKAAQQAVFGSQIDIANQ------LDKPVII----HTRSAGDDTIAMLRQHRAEKCGGVIHCFTETMEFKKA-SCSGIVTFKNAEAIREVIRYVPMER--------LLVETDSPYLAPVPYRGKENQPAYTREVCEYVATLKGVSAEAFAQ............................................................................................... 241

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ginalski K, Godzik A, Rychlewski L. Novel SARS unique AdoMet-dependent methyltransferase. Cell Cycle. 2006 Oct;5(20):2414-6. Epub 2006 Oct 16.