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Query: sp|Q63HM9|PLCX3_HUMAN PI-PLC X domain-containing protein 3 OS=Homo sapiens GN=PLCXD3 PE=2 SV=2, from H.sapiens

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MASSQGKNELKLADWMATLPESMHSIPLTNLAIPGSHDSFSFYIDEASPVGPEQPETVQNFVSVFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVFLDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFAQEVSLKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQASITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWVRTQKPGESGINIVTADFVELGDFISTVIKLNYVFDEGEANTLast
1 -73.400d2plca_ c.1.18.2 (A:) Phosphatidylinositol-specific phospholipase C {Listeria monocytogenes [TaxId: 1639]}  ali model 3D-neighbors follow..  20  1.........VTTKQWMSALPD---TTNLAALSIPGTHDTMSYNGDITWT----------------------LTKPLAQTQTMSLYQQLEAGIRYIDIRA-----KDNLNIYHGPIFLNASLSGVLETITQFLKKNPKETIIMRLKDEQNSNDSFDYRIQPLINIYKDYFYTTPRTDTSNKIPTLKDVRGKILLLSENHTKKPLQFGAPNQVIQDDYNGPSVKTKFKEIVQTAYQASKADNKLFLNHISATSLT---------FTPRQYAAALNNKVEQFVLNLTEKVRGLGILIMDFPE-KQTIKNIIKNNK......... 273
2 -72.000d2ptda_ c.1.18.2 (A:) Phosphatidylinositol-specific phospholipase C {Bacillus cereus [TaxId: 1396]}  ali model 3D-neighbors follow..  15  1..ASSVNELENWSKWMQPIPD---SIPLARISIPGTHDSGTFKLQN------------------------PIKQVWGMTQEYDFRYQMDHGARIFDIRGRLTDDN-TIVLHHGPLYLYVTLHEFINEAKQFLKDNPSETIIMSLKKEYEDMKGAEDSFSSTFEKKYFVDPIFLKTEGNIKLGDARGKIVLLKRYSGSNEPGGYNNFYWPDNETFTTTVNEKVKSIKDTMDETMNNSEDLNHLYINFTSLSSGGTAW------NSPYYYASYINPEIANYIKQKNP--ARVGWVIQDYINSPLLYQEVIRANKSLI...... 296
3 -10.400d2zkmx4 c.1.18.1 (X:312-660) Phospholipase C-beta-2 {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  15  4........................TQPLNHYFINSSHNT--YLTAGQFS---------------------------GLSSAEMYRQVLLSGCRCVELDC--KPPDEEPIITHGFTMTTDFFKEAIEAIAESAFKTSPYPIILSFEN-HVDSPRQQAKMAEYCRTIFGDMLLTEPLKPGVPLPSPEDLRGKILI................................................................................................................................ 149
4 -7.070d2pbdp_ d.110.1.1 (P:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  15  1............AGWNAYIDNLMADGTCQDAAIVGYKDSPSWAAVPGKTFVNITPAEVGVLVG----------RSSFYVNGLTL-----GGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVT--------TKTDKTLVLLMGKEGVHGGLINKKCYEMASHLRRS......................................................................................................................................................... 137
5 -7.030d2gc6a1 c.59.1.2 (A:297-425) Folylpolyglutamate synthetase, C-terminal domain {Lactobacillus casei [TaxId: 1582]}  ali model 3D-neighbors follow..  13  1..............WPARL-EKISDTPL--IVIDGAHNPDGINGLITALKQLFSQPITVIAGILADKDYAAMADRLTAAFSTVYLVPVPGTPRALPEA--------------EALHEGRLKDSWQEALAASLNDVPDQPIVI................................................................................................................................................................................... 113
6 -6.770d4qwoa1 d.110.1.0 (A:1-133) automated matches {Monkeypox virus [TaxId: 619591]}  ali model 3D-neighbors follow..  7  1...........MAEWHKIIEDISKNNKFEDAAIVDYKTTKNLAAIPNRTFAKINPGEVIPL-----------------ITNHNILKPLIGQKFCIVYTNSLMDENTY----------AMELLTGYAPVSPIVIARTHTALIFLMGKPTTSRRDVYRTCRDHATRVRAT......................................................................................................................................................... 131
7 -6.600d3d03a_ d.159.1.11 (A:) Glycerophosphodiesterase GpdQ {Enterobacter aerogenes [TaxId: 548]}  ali model 3D-neighbors follow..  11  46VVSGDIVNCGRPEEY-QVARQILGSLNYPLYLIPGNHDDKALFLEYLQPLCPQLGSDANNMRCAVDDFATRLLFIDSSRAGTSKGWLTDETISWLEAQLFEGGDKPATFMHHPPLPLGNAQMDPIHRLLALVERFPSLTRIF................................................................................................................................................................................... 192
8 -6.350d2xjpa1 b.179.1.2 (A:23-271) GLEYA domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 559292]}  ali model 3D-neighbors follow..  10  107FYTTPTNVTLEMTGYF--LPPQTGSYTFS---FATVDDSAILSVGGSIAFE-AQEQPPITSTNFTINGIKPWDGSLPDNITGTV--YMYAG-YYYPLKVVYSNAVSWGTL----SVELPDGTTVSDNFEGYVYSFDDD....................................................................................................................................................................................... 235
9 -6.330d2q4za_ c.56.5.7 (A:) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}  ali model 3D-neighbors follow..  13  2......................VAEEPIKKIAI-GTH--------------GNELTGVFLVTHWLKNGAEVHRAGLEVKPFITNPRAVEKCTRYIDLNRVFDLENLSKEMSEDLPYEVRRAQEINHLFGPKNSDDAYD-VVFDLHNTTSNMG......................................................................................................................................................................... 119
10 -6.140d3d9ya_ d.110.1.0 (A:) automated matches {Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896]}  ali model 3D-neighbors follow..  13  1.............SWQAYVDTSLGTGKIDRAAIVSRAGDSVWAASAGFNLSPQE--------------IQGLAAGFQDPPSMFGTGIILAGQKYITIRICVATKLCILVSHYPETTLPGEAAKITEALADYLVGV.......................................................................................................................................................................................... 124
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rodrigues AP, Grant BJ, Godzik A, Friedberg I. The 2006 automated function prediction meeting. BMC Bioinformatics. 2007 May 22;8 Suppl 4:S1-4.