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Query: gi|108885075|ref|NP_072661.2| DNA polymerase III, beta subunit (MG_001) [Mycoplasma genitalium G37], from M.genitalium

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKILINKSELNKILKKMNNVIISNNKIKPHHSYFLIEAKEKEINFYANNEYFSVKCNLNKNIDILEQGSLIVKGKIFNDLINGIKEEIITIQEKDQTLLVKTKKTSINLNTINVNEFPRIRFNEKNDLSEFNQFKINYSLLVKGIKKIFHSVSNNREISSKFNGVNFNGSNGKEIFLEASDTYKLSVFEIKQETEPFDFILESNLLSFINSFNPEEDKSIVFYYRKDNKDSFSTEMLISMDNFMISYTSVNEKFPEVNYFFEFEPETKIVVQKNELKDALQRIQTLAQNERTFLCDMQINSSELKIRAIVNNIGNSLEEISCLKFEGYKLNISFNPSSLLDHIESFESNEINFDFQGNSKYFLITSKSEPELKQILVPSRLast
1 -86.600[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)  ali follow..  19  1MKFVVSRNELGNLIKKIQSVVPQNTPI-PVLTHVLIETYNDELVFTATDLTVSTRCVTKAKVY--EKGAISIPSKRFFQLVKELTEANLEISSSAGEAQITSGSSCFRLLSMEKEDFPMLPDIQNAL-----RFSLPAEQLKTMLQRTSFAVSRE-ESRYVLTGVLLAIANGV-ATIVGTDGKRLAKIDAEVTLDSGEYIIPIKAVEEIIKMCSDEG--------EAAIFLDQDKIAVECDNTLLITKLLSGEFPDFSPVISTESNVKLDLHREELITLLKQVALFT-NESSHSVKFSFLPGELTLTANCTKVGEGKVSMA-VNYSGELLEIAFNPFFFLDILKHSKDELVSLGISDSYNPGIITD--SASGLFVIMPMR 362
2 -7.730[L] KOG1636 DNA polymerase delta processivity factor (proliferating cell nuclear antigen)  ali follow..  8  3....................................................................................................................................ELRLVQGSLLKKVLESIKDLVNDANFDCSSTGFSLQAMDSSHVALVSLLLRSEGFEHYRCD-RNLSMGMNLGNMSKMLKCAGNDD-IITIKADDGGDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPDAEYHSIVRMPSNEFSRICKDLSSIGDT-----VVISVTKEGVKFSTAG-DIGTANIVLRQNTTVKEPVSLSFALRYMNSFTKATPSDTVTISLSSE-LPVVVE-AEMGYIRYYLAP.. 253
3 -7.420[DL] KOG2810 Checkpoint 9-1-1 complex, RAD9 component  ali follow..  11  2....................................................................................................................................KYTLEGSNAR-VIAKAVQSLSK------VGKEMFIEIDQ-QSLQMRAINATQSAVGSISFKHSDFYCKISMKGCLAVFRNMNEVEY-------ELNLLDNQTNLQVNLRCKLETTKEATISIIDDQNI-TDQMPNIIRGDHKLLTDISNNFNSSEEE-----LTLEANSGSVVAKNYRTQLKLKPSEFEQYQVT-KETVITFCIKEFRAFLLFAENASLTLEFDEAGMPFLLKIKKHGEIECLLI... 254
4 -5.920[DL] KOG3194 Checkpoint 9-1-1 complex, RAD1 component  ali follow..  11  10..............................................................................................................................................KQIQSTLRCIDFSKECTIEITGLRFAVEESQSLQALDKSLFQTFNFQGDSDGDTYMFQTMISPLLQSLSIYTDGKERISTSAWDQPTVNIMHKVQYNGPGCPFIWEVEEMAGYATACELASTLCTKIIMKSNWLYDALVELDNNMGE--NLIIHTSSQKSTFLLRCVGAEYPNEKSVLESFETD-SENTYSYRFSLIRHALKALQGSKVNLRIDENGTLSI-QEGLCTFVDFCIVPL. 280
5 -5.620[S] KOG3852 Uncharacterized conserved protein  ali follow..  8  76....................................ESPTAHCNVLNWEQVQRLDGILSETIPIHGRGNFPTLELQPSLIVKVVRRRLAEKRIGVRDVRLNGSAASHVLHQDSGLGYKDLDLIFCADLRGEGEF----QTVKDVVLDCLLDFLPEGVNKEKITPLTLKEAYVQKMVKVCNDSDRWSLISLSNNSGKN---VELKFVDSLRRQFEFSVDSFQIKLDSLLLFYECSEN--PMTETFHPTIIGESVYGDFQEAFDHLCNKIIATRNPEEIRGLKYCNLLVRGFRPASDEIKTLQRYMRFFIDFSDIGEQQRKLESYLQNHFVGLEDRKYEYLMTLHGVVNESTVCLMGHERRQTLNL................ 399
6 -5.060[D] KOG1036 Mitotic spindle checkpoint protein BUB3, WD repeat superfamily  ali follow..  7  7.................SAGRELSNPPSDGISNLRFSNNSDHLLVSSWDKRVRL------DVSTNSLKGEFLHGGAVLDCCFHDDFSGFSVGADYKVRRIVFNVGKEDILGTHDKAVRCVEYFDFSILFFYTLCLFCDV------TGQVITGSWDKTVK------CWDPRGASGPERTQVGTYLQPERVYSMSLVGHRLVVATA--GRHVNIYDLRNMSQPEQRRESSLKYQTRCVRCYPNGTGYALSSVEGRFDLSEAAQAKKYAFKCHRKSEAGRDIVYPVNSIAFHPIYGTFATGGCDGFVNIKKRLYQYSKYPTSISALSFDGQLLAVASSYTFEE--VRSVNEIEVKPKPKVYPNPA.................. 353
7 -4.000[K] COG0195 Transcription elongation factor  ali follow..  10  3..............SEFMDALTTLEKEKGISKEVIIEAIEAAL-ISGYKRNFNQAQNVRVDVN-RENGSIRVFARK--EVVEEVFDARLEISLDEAK-----------------------GINPNYEVDDVVEIEVTPKDFGRIAAQTAKQV---QRVREAERGIIYADFIDREEDIMTGIVQRQDNRFIYVDLGKVEALLPLS--EQMPNESYRHNDRIKAYITKVEKTTKGPQIMISRTHPGLLKRLFELEVP-------------------EIYDGTVELKSVAREAGDRS-KISVHAENPEVDPVGACVGPKGSRVQTIELKGEKIDI---VEYVANALSPSKVVKVNVNEEEKTTQVIVPDYQ............ 312
8 -3.580[S] COG1934 Uncharacterized protein conserved in bacteria  ali follow..  7  52........................................................................................................................................................................................................................................................................FIDNVVIKQGTIEIKADKVVVTRPGGDQSKMIIEGFGNPVTFYQMQDSGKPVKGHGQKLRYEIANDFVVLTGDYLEQLDSNIKGDRITYLVKKQQ--MEAFSDKGKRVTTVLLP.. 164
9 -3.520[R] COG5222 Uncharacterized conserved protein, contains RING Zn-finger  ali follow..  14  1................................................................................................................................................................MSSTIFYRFKSQRNTSRILFDGTGLTVFDLK------------REIIQENKLGDGTDFQLKIYNPDTEEEYDDDAFVIPRSTSVIVKRS................................................................................................................................... 77
10 -3.280[J] COG0238 Ribosomal protein S18  ali follow..  10  26.............................................................................................................................................................................................................................................VDYKDTELLSRFVS----ERGKILPRRVTGTSAKNQRKVTTAIKRARVMA............................................................................................. 71
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.