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Query: gi|12044858|ref|NP_072668.1| tRNA modification GTPase TrmE (MG_008) [Mycoplasma genitalium G37], from M.genitalium

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKSEINIFALATAPFNSALHIIRFSGPDVYEILNKITNKKITRKGMQIQRTWIVDENNKRIDDVLLFKFVSPNSYTGEDLIEISCHGNMLIVNEICALLLKKGGVYAKPGEFTQRSFLNGKMSLQQASAVNKLILSPNLLVKDIVLNNLAGEMDQQLEQIAQQVNQLVMQMEVNIDYPEYLDEQVELSTLNNKVKLIIEKLKRIIENSKQLKKLHDPFKIAIIGETNVGKSSLLNALLNQDKAIVSNIKGSTRDVVEGDFNLNGYLIKILDTAGIRKHKSGLEKAGIKKSFESIKQANLVIYLLDATHPKKDLELISFFKKNKKDFFVFYNKKDLITNKFENSISAKQKDIKELVDLLTKYINEFYKKIDQKIYLIENWQQILIEKIKEQLEQFLKQQKKYLFFDVLVTHLREAQQDILKLLGKDVGFDLVNEIFNNFCLGKLast
1 -118.000[R] COG0486 Predicted GTPase  ali follow..  28  12VFMKETIVAQATAPGRGGIGILRVSGPKAVEVAHTVLGKC--PKPRMADYLPFKDSDGNVLDQGIALYFKAPHSFTGEDVLELQGHGGQVVLDLLLKRILQEGLRLARPGEFSEQAFLNDKLDLAQAEAIADLIDASSEQAARSALKSLQGEFSNKVNQLVDSVIYLRTYVEAAIDFPDEEIDFLADGKIEAHLNDIITQLDHVRSEAKQGSILREGMKVVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLREATDEVERIGIVRAWSEIEQADRILLMLDSTEADNQDLEKVRSEFSNIPVTIVRNKADLSGENEITLSAKTQQGIALLREHLKQSMGY--QTNMEGGFLARRRHLEALEQAATHLQQGHVQLTQFYAGELLAEELRRVQNHLSEITGQFTSDDLLGNIFSSFCIGK 465
2 -114.000[J] KOG1191 Mitochondrial GTPase  ali follow..  28  124FQSSSTIVAIVTPIGPGAVGIVRLSGPKAVEVARRVFRSAKRPKSHFVEYGAVVDSNGNVVDEVLAVPMLAPRSYTREDVVELQCHGSEVCLRRVLRTCVEAGARLAEPGEFTLRAFLNGRLDLSQAENVEKLISAKSSAAADAALEGIQGGFSSLVKSLRAQCIELLTEIEARLDFEDEMPP-LDIESVINKITSMSQDVESALDTANYDKLLQSGLQIAIVGRPNVGKSSLLNAWSKSERAIVTEVAGTTRDVVEANVTVRGVPITLLDTAGIRETNDIVEKIGVERSETAAKVADVIIMAVSAVEGWTEEDTELLRKIQKQPMILVMNKIDCAPPKSVFTSAVTGQGIEELEDAILEILGLDRVPTGGHQWTVNQRQCEQLVRTKEALVRLREAIEDEIPIDFWTIELREAALSLAQISGQDVSEEVLSSIFAKFCIGK 613
3 -49.100[R] COG3596 Predicted GTPase  ali follow..  13  1..............................................................................................................................................................................MVMKNFEVLQPLQNSLSGLPLWVSERILQ-----QINQLTHYEPVIGIMGKTGAGKSSLCNALFAGEVSPVSDVAACTRDPLRFRLQIGEHFMTIVDLPGVGESGV-RDTEYAALYREQLPRLDLILWLIKADDRALATDEHFYRQVYRHKMLFVISQSDKAEPPVCAVSVRLQWGLRVMAERMIKCLPREPSSPVVALLQHPFRTWVAREQARDDFGETVDTLDTVSTFPLIPAPVRTIIQAVRSSVVSV-ARAVWDFFF....... 289
4 -29.400[R] COG1160 Predicted GTPases  ali follow..  18  6..................VALVGRPNVGKSTLFNRLTRTRDAL---------VADFPGLTRDRKYGHAHIAGYDFIVIDT------GGIDGTEEGVEEKMAEQSLLAIDEADIVLFLVDARAGLTAADGIANYLRQRQNKITVVVANKIAASQGRGVTQLMEQVLAPFAEKMENADENDSEEEQDEWEQEFDFDSEEDTALIDDALDEELEEEQDKNIKIAIVGRPNVGKSTLTNRILGEDRVVVFDMPGTTRDSIYIPMERDGQQYTLIDTAGVRKVHLAVEKFSVIKTLQAIQDANVVLLTIDARENISDQDLSLLGFIAGRSLVIVVNKWDGLDQDVHFISALHGSGVGNLFDSIKEAYACATQKMTTSLL.................................................................... 397
5 -27.900[R] COG1084 Predicted GTPase  ali follow..  13  9...........................................................................................TDELLDKGFRRARKAASLKRSSKIPGQK-VIESTRVQTACQVIRDRLKMIIQRIPDI------ESLPEFYQDY------IDVTVGVDELKKSLGALNWAVGILNQLESDYMARIKRSKPSDASHLRRTVVIAGFPNVGKSTLLRTLTGA-EPEVADYPFTTKGIQIGHLERKWKRIQVIDTPGLDRPVEDMNNIELQAMVALENIADVIMFIFDASETCGYTLESQYSSVFDIPVVTVFNKMDLAENVKLKVSAFEGRGVSKIIKKLEGLYEKETREAHDNV..................................................................... 336
6 -23.400[R] COG1159 GTPase  ali follow..  22  11...........................................................................................................................................................................................................................IAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGPYQAIYVDTPGLHEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLRDKAPVILAVNKVDNVQEKVVPISAETGMNVDTIAGIVRKHLPEAIHHFPEDYITDRSQRFMASEIIREKLMRFLGA-ELPYSVTVEIERFVTNERGGYDINGLILVER------KKMVIGN 249
7 -22.100[R] KOG2486 Predicted GTPase  ali follow..  21  137..........................................................................................................................................................................................................................EFALVGRSNVGKSSLLNSLVRRKRLALTSKKPGKTQCIN------NDKWYLVDLPGYGYASAPHELK-TKDYFLNRSTLVSVFLLVDASIPVKPIDLEYASWLGQVPMTLIFTKCDKRKKKKIMTSSVTNQGRDEILLHMAQLRNY.............................................................................. 314
8 -19.300[E] COG4917 Ethanolamine utilization protein  ali follow..  17  3..........................................................................................................................................................................................................................RIAFVGSVGAGKTTLFNALQGNYTLA------------RKTQAVEFNDKGDIDTPGEYFNHPRWY----HALITTLQDVDMLIYVHGANDPESRLPAGLLDIGVSKRQIAVISKTDMPDADVFELNSHDPQSVQQLVDYLASLTKQ.............................................................................. 148
9 -18.700[R] KOG1490 GTP-binding protein CRFG/NOG1 (ODN superfamily)  ali follow..  14  106.........................................................................................................................ISKISKDYVKLLKYGDSLYRCKCLKVAALGRMCTVLKRITPSLAYLEQIRQHMARLPSIDPNTRT---------------------------------VLICGYPNVGKSSFMNKVTRADVD-VQPYAFTTKSLFVGHTDYKYLRYQVIDTPGIFEDRNIIEMCSIT-ALAHLRAAVLFFLDISGSCGYTIAQQAALSLFMNKPLVIVCNKTDLMPMENLKMSTLTDEGVMSVKNAACERLLD.............................................................................. 351
10 -17.900[R] COG0218 Predicted GTPase  ali follow..  20  27..........................................................................................................................................................................................................................EIALAGRSNVGKSSFINTMLNRKNARTSGKPGKTQLLNFFNID----KMRFVDVPGYGYARVSKKER-IEEYLTTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYPVIIVATKADKIPRGKILFSSVSKAGMDEAWDAILEKL................................................................................ 195
11 -17.000[R] COG2262 GTPases  ali follow..  15  9.............................................................EQAVLVHIYFTQDKDMEDLQEFSSAGVEALQVITGSRKAPHPKYFVGEGKAVE-VLFDHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVR-PGETQLETDRRLLRNRIVQIQSRLERVEKQREQGRQSRI--TVSLVGYTNAGKSTLFNRITEARVYAADQLFATLDPTLRRIDVADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIEAVNTVHEIPTLLVMNKIDMLEDFEVWLSAQTGAGIPQLFQALTERLSG.............................................................................. 363
12 -16.400[R] COG1163 Predicted GTPase  ali follow..  16  3............................................................................................................................TTVEKIKAIEDEMARTQKNKATSFHLGQLKAKLAKLRRELLTSASSGSGGGAGIGFDVA------------------------------RTGVASVGFVGFPSVGKSTLLSKLTGTESE-AAEYEFTTLVTVPGVIRYKGAKIQMLDLPGIIDGAKDGRGRG-KQVIAVARTCNLLFIILDVNKPLHHKQIIEKERLNKTPPDILIKKKEKGGISITNTVPLTHLGNDEIRAVMSE.................................................................................. 212
13 -16.300[T] KOG1487 GTP-binding protein DRG1 (ODN superfamily)  ali follow..  17  3............................................................................................................................STLAKIAEIEAEMARTQKNKATAHHLGLLKARLAKLRRELITPKGGGGG--------------------------------GPGEGFDVAKTGDRIGFVGFPSVGKSTLLSNLAGVYSE-VAAYEFTTLTTVPGVIRYKGAKIQLLDLPGIIEGAKDGKGRG-RQVIAVARTCNLILIVLDVLKPLGHKKIIENERLNSKPPNIGFKKKDKGGINLTATCPQSELDAETVKSILAE.................................................................................. 211
14 -16.200[R] KOG0410 Predicted GTP binding protein  ali follow..  13  141....................LEQLADTAGLAVVGSTYQKLASPNPRTYIGSGKVAEIKSAINAVETVIFDDELSPGQLRNLEKAFGGDVRVCDRT-ALILDIFNQRAATHE---------QVALAQMEYQLPRLTRMWTHLERQSGGQVKGMGEKQIEVDKRILRTQIGVLKKELE-----------------------SVRKHRKQYRSRRVAIPVPVVSLVGYTNAGKSTLLNQLTGAN-VLAENRLFATLDPTTRRVQMNGKEFLLTDTVGFIQKLPTTLVAAFRATLEEIAESSLLVHVVDISHPLAEQQIEAVEKVSSIPKLVVWNKVDRVDDPQICISALTGEGLDDFCNAVHEKLKDSMVWVEALLPFDKGDLLSTIHKVGMVKETEYTENGTLIRAHVPLRFAQLLKPMRHLVKDTSISQR............. 539
15 -16.200[T] KOG1486 GTP-binding protein DRG2 (ODN superfamily)  ali follow..  18  1...........................................................................................................................MGIIERIKEIEAEMARTQKNKATEYHLGQLKAKIAKLRTQLLEPPKGAS---------------------------------GGGEGFEVTKYGHRVALIGFPSVGKSTLLTMLTGTHSE-AASYEFTTLTCIPGVIHYNDTKIQLLDLPGIIEGASEGKGRG-RQVIAVAKSSDLVLMVLDASKSEGHRQILTKERLNKTPPQIYFKKKKTGGISFNTTAPLTHIDEKLCYQILHEY................................................................................. 210
16 -15.400[P] COG0370 Fe2+ transport system protein B  ali follow..  15  2.......................................................................................................................................................................................................................SQNTYCILGNPNTGKTSLFNALTGSYEY-VGNWSGVTVEKKVGT--LRSKTGKLIDLPGIYDLNPISRDETVVTRFLLEEKFDCMLNIVDSSQIERNLNLTVQLLEYGAPVVMGLNMIDVAAGPILPVVARSGKGTEDILSTLSEKH-------VAPAIPLVLQYGEPAEKAIKEIQALTKELIPAKQSRWLAIQFLSKNEVTEAFLTSNSAFEQLQQIRAE..... 229
17 -14.800[R] KOG2485 Conserved ATP/GTP binding protein  ali follow..  15  30............................................................................................................PGHM-AAATRAIRNRLKLSDLVIEVRDARIPLSSA-DLQSQMSAKRRIIALNKKDLANPNVLNVIRFFKWTRHFESSKQDCIAINAHSVMKLLDLVELKLKEVIAREPTLLVMVVGVPNVGKSALINSIHQLKRATVGPLPGVTQDIAGFKIA-HRPSIYVLDSPGVLVPSIPDIETGLKLALSGSVKDSVV.............................................................................................................................................. 234
18 -14.700[O] KOG0448 Mitofusin 1 GTPase, involved in mitochondrila biogenesis  ali follow..  13  15.........................................................................................................................................................KKGITAIFDQLLEFVTEGSHFVE--NPELDRIATEDDLVEMQGYKDKLSIIGE-----VLSRRHMKVAFFGRTSSGKSSVINAMLWDK-VLPSGIGHITNCFPKAKCALLRDDLVLVDSPGTDVTTELDSW-----IDKFCLDADVFVLVANSESTLMNTEKHFFHKVSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVANALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIR..... 343
19 -12.300[U] KOG0077 Vesicle coat complex COPII, GTPase subunit SAR1  ali follow..  15  18......................................................................................................................................................................................................................QKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELS----IGKIKFKAFDLGGHQIARRV---------KDYYAKVDAVVYLVDAYDKERFAESKR-EALATVPFLILGNKIDIPYAASEDELRYH--GLTNFTTGKGKVTLGDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIN.............................................. 193
20 -12.200[R] KOG0395 Ras-related GTPase  ali follow..  18  20.........................................................................................................................................................................................................................YRMVVLGASRVGKSSIVSRFLNGR--FEDQYTPTIEDFHRKVYNIRGYQLDILDTSGNHPFPAMRRL--------SILTGDVFILVFSLDNRESFDEVKRLKEAAELPMVICGNKNDHGELCRFEVSAKKNTNVDEMFYVLFSMA................................................................................ 190
21 -11.900[R] KOG2484 GTPase  ali follow..  15  153..........................................................................................VVLEVVDARDPLGTRCNEVERAVRGALVLNKADLVPRENLNNWIKYFRRSGPVTAFKASTQDQANRLGRRKLREMKTEKAMQGSVCIGAE-------------------LLMSMLGNYCRNKGIKTSIRVGVVGIPNVGKSSIINSLTRGRSCMVGSTPGVTKSMQEVELD-----IKLIDCPGI-GENSHAVLKNAQRVGDVKDPFTIAESVLK......................................................................................................................................... 356
22 -11.500[R] COG1161 Predicted GTPases  ali follow..  17  87...........................................................................................................................GQHDALIVNVVDIFDNGSLIPNLHKLTGGNDLLMVANKRDVLPKSLKVGKLTAWLREQAASRSLKPKDILVTSAQNKVAELMEAIEY---YRRGRDVYVVGVTNVGKSTLINAIIKSDVITTSRFPGTTLDKIEIPLDED---SALIDTPGIIHRGQIAHYLEPEDLKYVSPRKEI............................................................................................................................................... 264
23 -11.500[R] COG0536 Predicted GTPase  ali follow..  13  6..............................................................................DRVVLHLDGGNGCVSVHREKFKPLGGPDGGNG--------GGDIILEVTAQVHTLLDFHFHPHVKAERGANGAGDHRNGARGKDLVLEV-EKGETLADLTSVGMKFIAAAG-NAALASKARKAPGFALIGEPGEALKSMADVGLVGFPSAGKSSLISVMSAA-KPKIGDYPFTTLQPNLGVVNVGHETFTMADVPGLIPGASEGKGLGLD--LRHIERTSVLVHVVDTATMDPGRDDTGLGDLSQRPRLVVLNKADVPEAEEFIISAVARKGLDPLKYKLLEIVQDARKKRPKEKAESVIIKPKAVDHRTKGQFQIKPDPEVQGGFIITGEKPEEAVGYLADRLAKLGIEDGLRKA........ 423
24 -11.300[R] KOG0074 GTP-binding ADP-ribosylation factor-like protein ARL3  ali follow..  20  15......................................................................................................................................................................................................................DQEVRILLLGLDNAGKTTLLKQLASEDISHITPTQGFNIKSVQ----SQGFKLNVWDIGGQRKIRPY---------KNYFENTDILIYVIDSADRKRFEETGQ-EKLSCVPVLIFANKQDLLTAAPASEIALTGEGVQDGMNWVCKNVNA.............................................................................. 179
25 -11.100[U] KOG0071 GTP-binding ADP-ribosylation factor Arf6 (dArf3)  ali follow..  14  5........................................................................................................................................................................................................LFKGFSKPFSRLFSNKEMRILMLGLDAAGKTTILYKLKLNQSVVTIPTVGFNVETVT----YKNIKFNVWDVGGQDKIRPL---------RHYFTGTKGLIFVVDSADSNRISEARQ-REMRDCLLLVLANKQDLPGALSPAQIALTGDGLLEGLAWLSQNAKL.............................................................................. 183
26 -11.100[U] KOG0072 GTP-binding ADP-ribosylation factor-like protein ARL1  ali follow..  12  1........................................................................................................................................................................................................MDGGVLSYFRGLLGSREMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVEQVT----YKNLKFQVWDLGGQTSIRPY---------RCYYSNTDAIIYVVDSADRDRIGISKD-EELAGAILVVLANKQDMDGCMTVAEVATKGEGLDQAMDWLSNTLQS.............................................................................. 179
27 -11.100[UZ] KOG0073 GTP-binding ADP-ribosylation factor-like protein ARL2  ali follow..  17  3...........................................................................................................................................................................................................LLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFNIKTLE----HRGFKLNIWDVGGQKSLRSY---------RNYFESTDGLIWVVDSADRQRMQDCQR-ERLAGATLLIFANKQDLPGALSSNAIAVTGENLLPGIDWLLDDISS.............................................................................. 178
28 -11.100[R] KOG1489 Predicted GTP-binding protein (ODN superfamily)  ali follow..  15  91FVDVRIVKCKSGAGGSGAVSFFR-DGGAGGSVLGSLAKMKTTYTAEDGEAGAARQLDGMRGRDVLIQV---PWCLPPQKVRELVEREMRKDNSTAVNLSVSSGSHRKKIQLYRHEMAESWLFKDKAKEYHENKDWFKDLHKKMEAYDHSLEQSELFNDQFPLAGLDLNQPMTKPVCLLKGGQGGLGNMHFLTN----LIRNPRFSKPGRNGLELKSIADLGLIGLPNAGKSTILNKISNA-KPKIGHWQFTTLSPTIGTVSLGFDVFTVADIPGIIQGASLDKGMGLE--LRHIERSNGWVFVLDLSNKNPLNDLQLLEKVKTKNILIVCNKVDIDAEKS...................................................................................................... 469
29 -11.100[U] KOG0070 GTP-binding ADP-ribosylation factor Arf1  ali follow..  15  1........................................................................................................................................................................................................MGLSFGKLFSRLFAKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVE----YKNISFTVWDVGGQDKIRPL---------RHYFQNTQGLIFVVDSNDRDRVVEARD-DELRDAVLLVFANKQDLPNAMNAAEIATSGEGLYEGLDWLSNNIAS.............................................................................. 179
30 -10.800[R] KOG1673 Ras GTPases  ali follow..  14  102.........................................................................................................................................................................................................................LKISLLGDCQTGKTTFVVKYVGDENQSFLEMTGL--NLMDKTFYVQGISFSIWDVGG--------EKRSKDHIPIACKDAVAILFMFDLTSRSTLNSSQARKWNKTAIPILIGTKFDDFVRLPFFSSATHNINVNKIFKFILARLFNLPWKIDRN...................................................................... 276
31 -10.800[R] COG1100 GTPase SAR1 and related small G proteins  ali follow..  17  16......................................................................................................................................................................................................................NKELRILILGLDGAGKTTILYRLQIGEVVTTKPTIGFNVETLS----YKNLKLNVWDLGGQTSIRPY---------RCYYADTAAVIFVVDSTDKDRMSTASK-EELQDAALLVFANKQDQPGALSASEVAIKGEGITEGLDWLIDVIKE.............................................................................. 180
32 -10.600[V] KOG1707 Predicted Ras related/Rac-GTP binding protein  ali follow..  11  1...........................................................................................................................................................................................................MWMGVGDSSGSPKPIRIVVVGEKGSGKSSLIMAAARNT--FHPNIPSLLPYTLPSEFFPDRIPATVIDTSSRPEDKGKVV--------KEVRQADAIVLTFAFDRPETLDRLSFRQLEVRVPIIVAGYEVDNKEAYNIQWSAQRLDQAKDVLYYAQKAVIDPVGP------VFDQENNVLKPRCIAALKRIFLLSDHNMDGILSDEELNCEIKQMKNVMQVTFPQGVNERGLT...... 258
33 -10.400[R] KOG0075 GTP-binding ADP-ribosylation factor-like protein  ali follow..  14  18......................................................................................................................................................................................................................KEEMELTLVGLQFSGKTTFVNVIASGQ--FAEDMIPTVGFNMR-KITRGNVTIKVWDIGGQPRFRSM---------ERYCRGVNAIVYMVDAADLDKLEASRN-PQLAGIPVLVLGNKRDLPGALDETGLCKEKDNIDITLQWLIQHSKS.............................................................................. 183
34 -10.300[U] KOG0090 Signal recognition particle receptor, beta subunit (small G protein superfamily)  ali follow..  18  53......................................................................................................................................................................................................................TKSNTVLLSGLSGSGKTVLFYQLRDGSSSMEPNEGTFVLHNENNTKKGKVKPVHLIDVPGHSRLISKLE--------EYLPRAAAVVFVVDALEFLPNIRTNASVIKNKTPVLLCCNKTDKVTAHTKEFIRKQ............................................................................................... 193
35 -10.300[R] KOG2423 Nucleolar GTPase  ali follow..  15  170...........................................................................................................................IDSSDVVVQVVDARDPMGTRCR------HVEEFLRKEKPH--KHLVTVINKVDLVPTWVTRKWIGELSKEMPTIAGAVINLLRQFAKLHPDRPQISVGFIGYPNVGKSSLVNTLRKKKVCKTAPIAGETKVW--QYVMLMR--IYLIDSPGV-DSETQIILKGVVRVENVKDPENHVQGVLD......................................................................................................................................... 355
36 -10.200[U] KOG3887 Predicted small GTPase involved in nuclear protein import  ali follow..  11  60......................................................................................................................................................................................................................EVKPRILLMGLRRSGKSSIQKVVFHKMSPNETLFLESTNKICREDVSNSSVNFQIWDFPGQIDFFDP-------DYEMIFRGTGALIFVIDSQDDYMEALTRAYKVNTDINFEVFIHKVDGLSDDH------KIETQRDIHQRANDDLADAGLEKIHLSFYLTSIYDHSIFEAFSKV------------VQKLIPQLPTLENLLNIFISNSGIEKAF--LFDV..... 265
37 -10.100[TU] KOG1954 Endocytosis/signaling protein EHD1  ali follow..  16  2........................................................................................................................................YNFFRTVPRANRNEITFYPDYEEEGQKKKKTRSMFSWLGGDSSKKKNKEVLETVSEGLRKIYKQKLLPLEEFHKFHDFHS--MILLVGQYSTGKTTFIRYLLESDFPGIRIGPEPTTDVVDAKKQFRALSVTIVDTPGILSGEKQRIDRGYDFTGVLAERVDRIILLFDAHKLDISDEFKRCIEANEDKIRIVLNKSDMVDHQQLMRV.................................................................................................. 266
38 -9.970[T] KOG3886 GTP-binding protein  ali follow..  13  42..........................................................................................................................................................................................................................KVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATILDRIHSLQIGNLVLNLWDCGG---QDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCPDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECSCFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAEIIEAD..................................... 262
39 -9.750[R] COG3911 Predicted ATPase  ali follow..  17  8..........................................................................................................................................................................................................................VFVLTGGPGSGKTTLIAALRRAGFATSVVAG---RGIVRDQSSIGGTALPWSDRTLFAELMLSWEMRSYQNAVEQKG-----PVFFDRG....................................................................................................................................... 88
40 -9.520[R] KOG1424 Predicted GTP-binding protein MMR1  ali follow..  15  366.....................................................................................................................................................................................................KQELLELFKELHTGRKVKDGLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHF--QTLYVEP-GLCLCDCPGL-STKAEMTCSGIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKD.............................................................................. 538
41 -9.460[U] KOG0096 GTPase Ran/TC4/GSP1 (nuclear protein transport pathway), small G protein superfamily  ali follow..  15  13.........................................................................................................................................................................................................................FKLVLVGDGGTGKTTFVKRHLTGEEKKYIATIGVEVHPLSFYTNFGEIKFDVWDTAGQEKFGGLRDGY--------YINAQCAIIMFDVTSRITYKNRDLVRVCENIPIVLCGNKVDVKERKVKAISAKSNYNFEKPFLWLARKL................................................................................ 170
42 -9.410[U] KOG0076 GTP-binding ADP-ribosylation factor-like protein yARL3  ali follow..  14  1........................................................................................................................................................................................................MFHLVKGLYNNWNKKEQYSILILGLDNAGKTTFLETLKKEYSLAFKALEKIQPTVVATIPVDSKQILKFWDVGGQESLRSM---------SEYYSLCHGIIFIVDSSDRERLDECSTTEEIEGVPILMLANKQDRQDRMEVQDIALTGEGVKDAIEWMIVRLER.............................................................................. 188
43 -9.400[R] KOG1491 Predicted GTP-binding protein (ODN superfamily)  ali follow..  18  20........................................................................................................................................................................................................................NLKAGIVGLANVGKSTFFQAITRCPLGNPANYPFATIDPEEARVIVPSAHLTVYDIAGLTKGASAGEGLG-NAFLSHIRSVDSIYQVVRC--------------FDDAEIIHVEGDVDPVRDLEIINQELRLKDIEFAQKALEGAEKIAKRGGQSLEVKQKKEEMDLITKIIKLLES................................................. 199
44 -9.320[T] KOG4252 GTP-binding protein  ali follow..  15  10.........................................................................................................................................................................................................................IKMVVVGNGAVGKSSMIQRYC--KGIFTKDYKKTI-DFLERQIQVNDVRLMLWDTAGQEEFDAI--------TKAYYRGAQACVLVFSTTDRGSFEAVKVVAEVGDIPTVLVQNKIDLLDDSCIRTSVKEDLNVNEVFKYLAEKY................................................................................ 169
45 -9.050[OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase  ali follow..  16  1.....................................................................................................................................................................................................................MKRPLIIGVGGPVGAGKTMLIERLTGYSMAAITNDIYTKEDIEEMCDKHPDLQLLFLESGGDNLSATFSPDL-----------VDFSIYIIDVAQG--EKIPRKGGQGMIKSDLFIINKVDLAPYDFFVTNLKTDEGLKSVADWIEKRLQ............................................................................... 200

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Sikora S, Godzik A. Combination of multiple alignment analysis and surface mapping paves a way for a detailed pathway reconstruction--the case of VHL (von Hippel-Lindau) protein and angiogenesis regulatory pathway. Protein Sci. 2004 Mar;13(3):786-96. Epub 2004 Feb 06.