current user: public

If you have questions about the server, please let us know.

Query: gi|12044861|ref|NP_072671.1| hypothetical protein (MG_011) [Mycoplasma genitalium G37], from M.genitalium

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .
# Score Template Links and tools%idFirst MGKIKLKNRKALVVYDNKDDFEKNQTFALSLIKELQKKKLNAEVLLLENKDINFEAKINEAELILNRSRKVDFLKTNNQINTFLVNPFNVVFIANDKYETYKWLKQNRFLTVNSSLLSKETIKSFPVIVKKRNSHGGKDVHLVNSADEIKHLNIENATEWIVQPFLSIGTVEYRAYILFGKIIKVIKKISNANQFKANFSQGAEVSLFKLKWFTKRKIKKIAKRLREGYYAIDFFLNRYNRVIVNEIEDAAGARALVQLCPDLNITKIIIRTIISKFKKFLKKKLISLast
1 -55.400[HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)  ali follow..  11  17.RHYRRGFMRIAFFVNSIETEGP-TFATGLLAMAALNRGHDVVYLTPGDFTLRSDDDVEEIDALMLRHAGILFGRLAEQRGVVVLNDPEGLALAQNKLYF---QSFPEIVRPTTLISRNVEEIPKGVIVKPLQGSGGKNVFKIGSSKETNFEAVSLEGYLIAQAYLPAKEGDVRFFMMNGRPLMRDGRVPAKGDLRSNIHANGTAEAVKVTDEIVELAEMMRPKLGMFLVGLDIV---GDKILEVNVFSPGGLSNILEL-TNVDFSDTIIEAVETKVSMQAASG... 360
2 -28.100[R] COG1821 Predicted ATP-utilizing enzyme (ATP-grasp superfamily)  ali follow..  14  55.......................PVDSMDSMEKYLEKSDAFLIIAPEDDFLL------------------YTLTKKAEKYCENLGSSSRAIAVTSDKWELYKKL-RGEVQVPQTSL----RPLDCKFIIKPRTACAGEGIGFSDEVPD----------GHIAQEFIEGINLSVSLAVGEDVKCLSVNE-----QIINNFRYAGAVVPARISREVVEEAVRAVECVENGYVGVDIVY--SDQPYVIEINARTTPVVAFSRAYGASVADLLAGGEVKHVRRQMVRK... 282
3 -26.900[M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes  ali follow..  11  2........KIAVLYGGTSAEREVSLSSGKGIMEALKANGHEVIGIDFHPDQVRDLVD-LDVDLVFIGLHG-KVQALLDLLNIPYVGTVQGSALAMDKAKAKLFFEKAGIRVAEEVVLHSFTTGTYPVVVKPNQEGSTIGLTVAETEEELLQGIERHDDTILIEEFIA--GTEVTVAVLGNKPVVEIVPKNKLYDYESKYAPGMSEHIVEHTAYVQQAAVRAHQALGCVYSRVDFIVPNDGDPVILKVNTLPGMTPTS-KGVGMSYEEMIQTFVNLSLKK........ 305
4 -23.700[R] COG3919 Predicted ATP-grasp enzyme  ali follow..  14  18..............................LARSLGVLNVPVYYLTHDSPLPGWSRFVRET--LLVPSGDGEVQEELSALYKIILPEWTNLQWLCEKPLLYKRAAELGVSIPRTYALTSAADVMFPVILKPHMGGGNTSVIRADDREELKAAFVDASGNVVVQELIPGGGESQFSYAANGEPIAEFTARRAR-QYPVDFGYTSTRVEVVDNRQAIEAARKILKSAGSGLVEVEFKLDRDGALKLLDVNPRPWSWFGLCSAAGINLGGLLWRVANDM........... 313
5 -23.500[TU] KOG3895 Synaptic vesicle protein Synapsin  ali follow..  11  82.PAFSKDKYFTLLVLDDQNTDWSKYFRGRRLVEQAEFRDITVVSSADTGPVVTMAARSFRPDFVLIRQP--STILGLKYGGVPSINSLHSIYQFQDKPWVFSHLLQDGFPLIEQTFFPNPRDLKFPSVLKAGHCHGGVATARLENQSALQDAANDSHCYCTIEPYIDAK-FSVHIQKIGNN-YKAFMRKSITGNWKTNQGS-AMLEQITLTEKYKSWVDEISELFGMEVCGLSVVVAKDGREYIISACDSTALIGDTQEEDRRQIADLVSGRMQNVCRPSMAQT... 462
6 -23.500[R] COG2232 Predicted ATP-dependent carboligase related to biotin carboxylase  ali follow..  12  1.....MSKMEEILVIG---------VNTRPVVESAFRLGYRVYSAGYYC-NFSQEKLLEAASDFIERADGIIPLTGAPPLPGEKVLGNSRVDHVEDKYRLYRRI-RNSYPTPETHLISDPAEAEKKYIAKPVSGAGGFGVTEFREGDG----------EFLLQEYIEGVPVSASVLSTGEDTVLTSRQIIDRGV-EGQFVYAGNMTP-GPSGEIEDLASDLILDLSLGSNGVDLIMRDSE-LYVIEVNPRIQGTECAEASLGINMVDAHIRACMGELIEKPDPV... 296
7 -23.500[R] COG1759 ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases)  ali follow..  2ITREQVLEVLEKYDKDKITIGVIGSHSALDIADGAKEEGLPTLVVAQRGRHIEIQEELRKRNVIFVPNRSFVVYRVENEFLVPMFRSLLRTEERSEEKSYYWLLEKAKLPYPEPVSPEEDDVGLVIVKLPHAKKRLERGFFTAASYKEFKEKSEKLLAKARIERYIIGPVFNFDFFY---ELLGIDWRFETSLDGHVRCGHASSTLRESLLEKVFDMAEKYVEATPPGIIGLQTAVDKDLNFYIYDVAPRTGGGTNIHMAMGHPYGNSLWRKIKRAIELDELEKIVT 380
8 -21.400[F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)  ali follow..  13  25............................KEVVIELQRLGVEVIAVDRYA-ALKALVEKEKPDYIVVEAIATATLVELEQAGFTVIPTAKATQLTMNREGIRRLAEELGLPTSNYQFVDNFDDFGIPCVVKPIMSSSGHGQSILKSVEQIPSAWEYAQQRVIVEGFVKFD-YEITLLTVHGTSFLAPIGHIQIDGDYRESWQPQAMSA-VALEKAQAIAEKITGALGRGIFGVEMFVCGDE-VIFNEVSPRPHDTGVTLISQELSEFALHARAILG............ 309
9 -19.900[F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)  ali follow..  11  24............................RMLAMAAARLNHRTIVLEPQA---ALAELASRCDVVTYEFENVPVAAAEKLSAVPVYPPAQALSASQDRLTEKRFLNGCGIPTADFRAVDSQDELGGKGVLKTRRGYDGKGQRLFRGGENLTGAFAALGGPLILESFVAFE-REISIIAADGTVTCYDPAENVHLNGILHTSTVPAALSDAAKAVAVQSAEKLLAALEVGVIGIEFFVLPDGSLVANEMAPRVHNTGWTEAACAISQFEQHIRAVSD............ 301
10 -19.100[I] COG0439 Biotin carboxylase  ali follow..  12  86...................................................................AENPDFAEMCREHGIVFIGTPESMRALGSKAGGREIAAQSNVPTVPDAALLAAKQIGYPVLLKASAGGGGRGQKVIRTQEELQKGFNQAQEEIIMEKFLEEF-RHIEVQVMGGHVIHIGERDSIQRRNQKLIEEAPSTLPESLRQEILAAGVRLAQFVNYAGAGLEFIMDRDGNYYFMEMNTRIQVECVSEMISSLDLVRLQIEIAAGLGLNIQQDDV.. 326
11 -18.000[EF] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)  ali follow..  10  3....KRTDIQKIMVIGS--QAAEFDYAGTQACLSLKEEGYEVVLVNSNPATIMTDKEIADPDALLPTAMELSKNGILDELGVELLGKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEIGYPVIVRPAFTLGGTGGGMCANEKELREITENGVTQCLIERSIAGF-KEIEYEVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQQMLRDASLSIIRALKIGGCNVQLLDPNSFKYYVIEVNPRVSRSSLASKATGYPIAKLAAKIAVGLTLDEVINPV.. 338
12 -17.100[I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit  ali follow..  11  15.............................RIIRACRDYGLQSVAVYADPDQDALFVRLADEAYALFLSERAEFAQAVIDAGLIWIGDPDVIEALGDKVMARRIATGVGAPLVAAEVTAFAEQHGLPVAIKAAHGGGGRGLKVAWKMEEIAELYESAVRECFLERFLDRP-RHIEAQVIAGNVLVLGTRDCSLQRRNQKLIEEAPAPFLEQRQKIHDAAKAICAAAGYSGAGVEFLLGVDGTISFLEVNTRLQVEPVTEETTGIDLVIEQFRIAEGH........... 318
13 -15.400[IE] KOG0238 3-Methylcrotonyl-CoA carboxylase, biotin-containing subunit/Propionyl-CoA carboxylase, alpha chain/Acetyl-CoA carboxylase, biotin carboxylase subunit  ali follow..  42.IDYNEPKFDKILIANRGEIA--------RVIKTARAMGIKTVAVHSDDEAVCVGEAPTAKSYL-FLSENTKFAAELEKAGAKFIGNSKAILDMGDKIHSKKIATAARVSMIPDMCVKVSRDIGYPVMIKASAGGGGKGMRVAWNDKQAREGYRLSKQEMLVEKFIDNP-RHIEMQVLCGNALWLNERECSIQRRNQKVIEEAPSSFVEMRRKMGEQAVQLAKAVGYDSAGVEFLVDSQRNFYFLEMNTRLQVE-ITECITGIDIVQQMLRVSYGHPLPITQEQV.. 375
14 -14.900[C] COG1038 Pyruvate carboxylase  ali follow..  17.CGETVLKISKILVANRSEIA--------RVFRAANELGIKTVAIWAEEDKLSLHRFKADESYQVLLSESPEFVEACNKAGITFIGTPDTMRQLGNKVAARNLAISVDVPVVPAEVERMAEEIGYPVMLKASWGGGGRGMRAIRKKEDLAREVTEAKREVYLEKLVERA-RHVESQILGGNVVHLFERDCSIQRRNQKVVERAPAPYLAQRQELAAYSLKIAAATNYIGAGVEYLMDADGKFYFIEVNPRIQVETVTEVVTGIDIVKAQIH................ 344
15 -14.300[F] COG0151 Phosphoribosylamine-glycine ligase  ali follow..  10  53...........................IPALVKFAQDKQIGLTIVGPEAPLVI------------------GVVDAFREAGLKIFGPAKAAQLEGSKAFTKDFLARHKIPTAEYQNFTEVEPAGTPIVVKADGLAAGKGVIVAMTLQEAEDAVRDAGSRVVIEEFLDGEEASFIVMVDGKNVMASSQDHKRVGENDTGLNTGGMGAYSPAPVITPEIHSRIMKEVGNVYTGFGLMIMPNGQPKVIEFNGDPETQPIMLRLKS-DLVELCLKACDGKLDE........ 321
16 -14.000[F] KOG2835 Phosphoribosylamidoimidazole-succinocarboxamide synthase  ali follow..  12  16............................RMIVEAANRLNIKTVILDAENSPADIEKLAEKCDVLTIEIEHVDVPTLKKHPKLKIYPSPETIRLIQDKYIQKEHLIKNGIAVTQSVPVEQARDLGFPFVLKSRTAYDGRGNFVVKNKEMIPEALEVLDRPLYAEKWAPFT-KELAVMIVNGLVFSYPIVETIHKDNICDLCYAPARVPDSVQLKAKLLAENAIKSFPCGIFGVEMFYLETGELLINEIAPRPHNSG................................ 278
17 -13.300[E] COG0754 Glutathionylspermidine synthase  ali follow..  11  162FAELREQYGFQLLHLTCCRDTVEDRGTIQYLQDCAAEAEIATEFLYIDDIGLGEKGQFTDLQ-NLFKLYPWEFSTKLEDAGVRWLEPAWKS-IISNKALLPLLMFPDHPNLLPAYFAEDEHPPMDKYVVKPIFSREGANVSIIENGKTIEVEGPYGEEGMIVQQFYPLPKFGIGSWLINDQPAGIGIREDRA............................................................................................... 370
18 -12.700[O] KOG2158 Tubulin-tyrosine ligase-related protein  ali follow..  15  199....................................................................................INHFPGMIEICRKDLLSRNLNRML--FPKTWMLPADLNHKRTFILKPDSGAQGRGIWLTNDLKTIGP-----HERLICQTYIHRP--DLRVYTLEGLARFATNKYVEPTP--TNYSVNKRNSHYELCDNVDDVIIKTVLSAWFEILGFDILVDWKLKPYILEVNHSPSFHT--NEQVDREVKRPLIRDTLNLVSTVLADK... 482
19 -12.100[F] KOG0237 Glycinamide ribonucleotide synthetase (GARS)/Aminoimidazole ribonucleotide synthetase (AIRS)  ali follow..  11  59...........................FEQLVKFALDKDVNLVIPGPELPLVE------------------GIEGHFRRVGIPCFGPSAAARMEGSKVFSKDFMHRNNIPTAVYKSFSNYDHATFDVVIKADGLAAGKGVIIPKTKKEAFEALESAGKNVVIEELLEGEELSILTFSDGYTCLPPAQDHKRAFDGDKGPNTGGMGCYAPTPVASPKLLETVQSTIGYPLVGIGLMLTPSG-PRVLEYNGDPETQAVLPLLES-DLAEIILACVNHRLDA........ 326
20 -12.100[O] KOG2157 Predicted tubulin-tyrosine ligase  ali follow..  14  275................................................................................RSYEMTRKDRLYKNIERMQHLRGMKHFDI-VPQTFVLPIENKHRGPWIVKPAASSRGRGIFIVNSPDQIPQ-----DEQAVVSKYIVDP--DLRVYVLEGIVRLATVKYDRHAD--CNYSINKYHSDYIRSSDIEDLIIKAVLACAFELYGFDILIDNALKPWLLEINLSPSMGV--DSPLDTKVKSCLMADLLTCVGIPAYSP... 553
21 -9.960[S] COG2308 Uncharacterized conserved protein  ali follow..  12  290..............................YEHAYLARLMGVPLVEGRDLVVHENMGLRRIDVIYRRVDDDFLFNAYRAGNVVICNAPGT-GVADDKAVYAYVAILPNIETYLCREPRQLSHV--KLVVKAVGASGGYGMLV-KERDDFALAIKADPENYIAQPTIQLSTADLRPFILSGETPGALTRVALRGSLVVNSSQGGGSKDTWVLADDAPSNGNGHGS............................................................... 542

FFAS is supported by the NIH grant R01-GM087218-01
1 3 6 8 8 6   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Jaroszewski L, Rychlewski L, Godzik A. Sensitive sequence comparison as protein function predictor. Pac Symp Biocomput. 2000;:42-53.