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Query: gi|12044856|ref|NP_072666.1| thymidylate kinase (MG_006) [Mycoplasma genitalium G37], from M.genitalium

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNKGVFVVIEGVDGAGKTALIEGFKKLYPTKFLNYQLTYTREPGGTLLAEKIRQLLLNETMEPLTEAYLFAAARTEHISKLIKPAIEKEQLVISDRFVFSSFAYQGLSKKIGIDTVKQINHHALRNMMPNFTFILDCNFKEALQRMQKRGNDNLLDEFIKGKNDFDTVRSYYLSLVDKKNCFLINGDNKQEHLEKFIELLTRCLQQPTHYLast
1 -84.800PF02223.17; KTHY_BACSU/8-199; Thymidylate kinase  ali follow..  34  1........FEGPEGAGKTTVLQEIKNILTAE--GLQVMATREPGGIDIAEQIREVILNENMDPKTEALLYAAARRQHLVEKVKPALEQGFIVLCDRFIDSSLAYQGYARGLGIDEVLSINEFAIGDMMPHVTVYFSIDPEEGLKRIYANGSREK-NRLDEKLDFHTKVQEGYQELMFPERFHSVDAGQSKDLVVQDV............. 192
2 -19.400PF01712.19; DCK_BACSU/12-212; Deoxynucleoside kinase  ali follow..  13  1......ITVAGTVGVGKSTLTKTLAKRLGFK-------TSLEE--VDHNPYLEKFYHDFERWSFHLQIYFLAERFKEQKTIFEGGFVQDRSIYEDTGIFAKMHAKGTMSKVDYKTYTSLFEAMVMTPHPDVLIYLEGDLENILNRIEQRGREMELQTSRSYWEEMHTRYENWISGFNACPVLKLRIEDNDENSIENIVDQIASVIH.... 201
3 -17.600PF00693.18; KITH_VZVD/19-298; Thymidine kinase from herpesvirus  ali follow..  15  1..........GAYGIGKTTAAEEFLHHFAIT--PNRILLIGEPAGEDAICGIDVSPEDAQRLTAHFQSLFCSPHAIMHAKISAVNKEPYKIMLSDRHPIASTIC---VGDMSPAALPGLLFTLPAEPPGTNLVVCTVSLPSHLSRVSKRARPGE----TVNLPFVMVLRNVYIMLINT................................ 194
4 -17.000PF18751.1; S5Y5G5_9CAUD/1-187; P-loop Nucleotide Kinase3  ali follow..  10  2..TARLIYLVGQPGSGKSTLMSALTAGFDRHKI---PAPDYPVAHDVLADKTTGEVVGAELGVRRELFSGTDALPSSIIDKAAPWVRSQPLLLAERLANRRFIDAALEGGYEVTLV---------------LLDHNDAEDWRKVRSKAIGKTQNPSWVKGRLSASRNLADALSG--PAYEGKAVEVLRGHPDPIRSILKGIDA....... 187
5 -16.400PF18748.1; A0A0A0YSQ1_9CAUD/11-206; P-loop Nucleotide Kinase1  ali follow..  11  15.ARGELFYVKACNGAGKSTIPSYCAERDPEAYT-ILLTVMPSYGMLAFGKYDKSKSKGVDSLKDYDEM-------KKAVELSELEEFIGYTAFFEGVIPST-------------ILHTWVEYLNRPARPLTTVFIDTDLETCLSRVNSRNGGAEFNA--------DLVTEKFNRVMSHKTRHKELFPSVPAVTIRSQGITIDEMVS.... 196
6 -15.300PF07931.12; Q98FG2_RHILO/59-238; Chloramphenicol phosphotransferase-like protein  ali follow..  10  1...ARIVLLNGVGSAGKSSIARALQTITAAPFLHVQMMLPDALQDHADGFSYETVRQDGKPAVVIRAGPVGERTLRGMRHAIAAMAGQGNDLIVDDVLCNGEL---------SDCVDLLSAFDF------HLVGVMAPLEVLEAREARRADRLPGLARWQYERVHAGISYDL----------EVDTSQTPLECARRIQQRFQ........ 180
7 -15.300PF13521.6; A4CIV1_ROBBH/14-173; AAA domain  ali follow..  16  2......VVLFGPESTGKTTLARELARHY---------------GEPWVPEYAREYLQEQQTCAPEDLLPIARGQMRLENIGAR---EASRLLICDTDLLETKVY---SETYYGGGCDPKLQAAALANDYDLYFLTDIDIP-------------EADDLRDKPHERAEMFHYFKTALRENNRRFVILSGGREA.................. 159
8 -14.900PF13671.6; B2JHT3_PARP8/20-178; AAA domain  ali follow..  13  1.....LVFICGHAGTGKTTLAKRLIGPLMKATGEACCLLDKDTLYGVYSAAAIGALTGDPNDRDSPLFLQHFRDPEYLFDTAAENLRLGIGVIAV---------GPLSREVRERRLFDHVWLGVPKDAKISVVWVSTSEETARERIAARGNPNDAYKLAHWEDYRQR........................................... 155
9 -13.600PF00625.21; KGUA_ECOLI/4-186; Guanylate kinase  ali follow..  14  1...GTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVHTTRQPRPGEVHGEHYFFVNHDEFKEMLEHAEVFGNYYGTSREAIEQVLATGVDVFLD------IDWQGAQQ--------------IRQKMPHARSIFILPPSKIERRLRGRGQ-------DSEEVIAKRMAQAVAEMSHYAEYDYLIVNDDFDTALTDLKTIIRA....... 182
10 -12.200PF13207.6; E3JVW4_PUCGT/16-151; AAA domain  ali follow..  20  2..........GGPGAGKGTQCARLVDQYSFVHLSAGDLLRAERDGSTYGSMIKDYIREGKIVP-----------MQVTIKLLENAIGAAVAQGKTRFL-----VDGFPRQMD-----QAVKFDEDVCQSSFVLFLTCPEETLLKRLLERGKTS......................................................... 125
11 -11.700PF00485.18; KPPR_SYNY3/10-192; Phosphoribulokinase / Uridine kinase family  ali follow..  1.....LIGVAGDSGCGKSTFLRRLTDLFGEEFM---TVICLDDYHSLDRQGRKAAGVTALDPRANNFDLMYEQ---------IKTLKSGQSIMKPIYNHET------GLLDPPEKVEPNKVVVIEGLHPDFGVYLDISEEVKINWKIQRDMAERGHTYEDILASINARKPDFTAYIEPQK.............................. 167
12 -11.700PF08433.10; O46079_DROME/1-293; Chromatin associated protein KTI12  ali follow..  12  3.....LVVITGLPASGKSTRARQLRDHFVERGRKVHLISE---------NEAVPKAGFGKNSHTGDSQKEKVVRSD-LKSEASRHLNQEDLVILD----AGNYIKGY---------YELYCMSKVSRTTQCTVFTCIPQEEAWTFNSQRTAPDELPGDSERVQPVDNSDVPYTRETFDALCQRYEEPQSNNRWDSPLVVV.......... 175
13 -10.400PF00406.22; KAD2_CAEEL/31-217; Adenylate kinase  ali follow..  17  1........FIGPPGSGKGTQAPAFAQKYFSCHLATDLLRAEVASGSEFGKELKATMDAGKLVS------------EVVCKLIEQKLEKPE-------CKYGFILDGFPRTSGQAEKLD-EILERRKTPLDTVVEFNIADDLLVRRITGR............................................................. 123
14 -10.000PF03976.14; PK21_MYCTU/32-260; Polyphosphate kinase 2 (PPK2)  ali follow..  13  29.GARLVVIFEGRDGAGKGGAIKRITEYLNPR--VARIAALPAPTDRERGQ-------------------------WYYQRYIAHLPAKGEIVLFDRSWYNRAGVEKVMGFCTLRQTPIFEQMLIDDGILLRKYWFSVSDAEQLRRFKARRNDPVRQKLSPMDLESVYRWEDYSRAKDESPWYVVESDIKKHARLNMMAHLLSTI...... 221
15 -9.970PF13238.6; A0B5Y2_METTP/3-117; AAA domain  ali follow..  13  1......IALTGTPGTGKTTVSGLLPFR-----------------VVNLNDLIRDGMSAGFDPERECLEADMDALEEKIEEIERSCGDDVLIIEGHFAHHFA----------------------------DEAIVLRLHPNVLRRRLEARGASKIRENVEAEA................................................ 113
16 -9.780PF07652.14; Q32ZD8_9FLAV/1675-1822; Flavivirus DEAD domain  ali follow..  17  1FKKKQLIVLDPHPGAGKTRKV--LPEFIRQAVERRLWTLALAP--RVVAAEMAEALNGLPVRYLTPAVIQQHTGKEIVDLMC-GRVPNYNMFIMDEAHFTD............................................................................................................. 108
17 -9.650PF01121.20; COAE_HAEIN/3-181; Dephospho-CoA kinase  ali follow..  16  1....YIVGLTGGIGSGKTTIANLFTDLVDADVVAREVVAKDSPLLSKIVEHFGAQILTEQ-AALRERVFNHDEDKLWLNNLLHPAIRERMKQKLAEQTAPYTLFV----------VPLLIENKLTALC-DRILVVDVSPQTQLARSAQRDNNNFEQIMNSQVSQQERLKWA----------DVINNDAELAQ.................. 179
18 -9.610PF05729.12; G3V6C0_RAT/441-610; NACHT domain  ali follow..  12  2......VAVLGKAGQGKSHWARTVSIWAQGQLPQYDFVFY----------PCQCLDRPGDTYHLRDLLCPPNLQPLAMDDEVIDHIVRQPLLILDAFEELEAQDSLLHGPCGPLSPEPLAGLFQRKLLRGCTLLLTARPRGRLAQSLSK-----ADAIFEVPSFSTKQAQIYMR.................................... 165
19 -9.560PF01583.20; PAPS1_HUMAN/51-209; Adenylylsulphate kinase  ali follow..  18  1..RGCTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTL----------GDNIRQGL-------NKNLGFSPEDREENVRRIVAKLFADAGLVCITSFISPYTQDRNNARQI-----------HEGASLPFFEVFVDAPLHVCEQR--------------DVKGLYKKARAGEIK.................................... 133
20 -9.430PF06414.12; Q8P580_XANCP/35-230; Zeta toxin  ali follow..  12  11FEHPKAIILAGQPGSGKGSLARAADVELGRDVVLID------------PDELRNAHPERNAHPYTWSGYTHSDASQWADELLQVTIEGKKNLIFDTTLSNGQWS-----------AELIKDLQSRGYDVEV-RAMAAHKLESEHGVDSRFSQQLDREGYGRYVPESHREVVYTRLPISAPVRIFNRQGAE.................... 189
21 -9.420PF03308.16; Y2483_CAUVC/22-294; Methylmalonyl Co-A mutase-associated GTPase MeaB  ali follow..  14  31.GRAQRIGITGVPGAGKSTTIERFGCNLVEAGHRVAVLAV-DPGGSILGDKTR-----EQLSVQANAFIRPSPSGGALGGVARKT--REAMLLCEAAGFDVVIIETVGVGQSETVVADMVDIFLALLIPGG--LIELADLLVINKADADPAKAERSARDYRNA............................................... 198
22 -9.170PF00004.29; LON_BRECH/351-493; ATPase family associated with various cellular activities (AAA)  ali follow..  16  1......LCLVGPPGVGKTSLARSVARALGREFVRISL------GGVRDEAEIRG-----------HRRTYVGALPGRIIQGMKQAGTINPVFLLDEIDKLASDFRGDPASALLEVLDPNQNDKFSDHYIEETYDLTNVMFITTANSLDTIPRPLLDRME................................................... 136

FFAS is supported by the NIH grant R01-GM087218-01
1 4 2 0 4 4   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I. and Godzik A Connecting the Protein Structure Universe by Using Sparse Recurring Fragments. Structure (Camb.) (2005) Aug;13(8):1213-24