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Query: gi|12044857|ref|NP_072667.1| DNA polymerase III subunit delta` (MG_007) [Mycoplasma genitalium G37], from M.genitalium

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLTTTHALLIIQRKGSFLKPFLDNYLTSIVCENKNGCKKCINCLEILNNKYNSLYWFDQINPFKRENALQLARIFNRERTSVNNKNIYLIEEIEKLSSNSINSLLRLVEDSPINSYGIFTTKNESLILSTFLSRVQKVVLKKASKVPFKVSKNDQEIITSFFTVDEQIEAIENGSFNRFKIILDACLNKKTGTEQIYHAWQIFRDFSNSEIAQLITLIINKTENIDKKSILFNCLKVLPYNPPKSTLFANLVSWLast
1 -72.100PF13177.6; A5VIC8_LACRD/13-171; DNA polymerase III, delta subunit  ali follow..  23  15.NELAHAYLFVGPGGSGKMSIAQWLSLRLFCLHNEPDLTCAECQRILSGNHPDIVYAAPEGRQKVDEIRRLKAEFSK-SAVEGNKKIFIIKDADKMTNGAANSLLKFIEEPGAGVYIFMLTTNKSAVLPTIRSRTQVIELPPL............................................................................................................... 159
2 -28.900PF05496.12; RUVB_BACAN/21-179; Holliday junction DNA helicase RuvB P-loop domain  ali follow..  35......HVLLYGPPGLGKTTLANIIANEMGVNVRTTSGPAIERPGDLA---AVLTSLQPGDVLFIDEIHRLHRSIEEV-PAMEDFCLDIVIGKGPSA--------RSVRLDLPPFTLVGATTRAGALSAPLRDRFGVLS................................................................................................................... 157
3 -22.800PF05673.13; Q0K6N5_CUPNH/29-287; Protein of unknown function (DUF815 topsan)  ali follow..  55.KLPANNVLLTGARGTGKSSLIKACLNAFVRDG------------------LRLVEVDK------DDLGDLGDIVELVAQRPERFVIFCDDLSFEEGESGYKSLKSALDAQSDNVLIYATSNRRHLLPEYMKDNETHTDDGEIHPGEVVEEKISLSKQDEYLAIVGHWLRHFGCTDEDIAAARGDALVWALER----------GSRSGRVAWQFARDWGGKH................................ 259
4 -14.600PF00004.29; LON_BRECH/351-493; ATPase family associated with various cellular activities (AAA)  ali follow..  14  1.......LCLVGPPGVGKTSLARSVARALG----------REFVRISLGGVRDEAEIRGHRRTYVGAL----RIIQGMKQAGTINPVFLLDEIDKLASDPASALLEVLDPNQTNVMFITTANSLDTIPRPLLDRMEVISIS................................................................................................................. 141
5 -13.600PF03266.15; NTPTH_METAC/3-167; NTPase  ali follow..  10  2.......IAVTGSPGVGKSTVVAKTAEKLAEKPGFKIGGIRTAEIRKEGHREGFSIRDLATGKTGINLDDLERIGANAVRNALACDLVVIDEIGPMELISFVSAVEEVLESDKPVLAVLHHSSRHPLAQRFRKGFEVLTVDKGNRDELPEKI...................................................................................................... 164
6 -13.100PF07724.14; Q7PAG5_RICSI/595-759; AAA domain (Cdc48 subfamily)  ali follow..  12  1..RPLGSFLFLGPTGVGKTELTKALAGFLFDDR-------NAILRIDMSEYMEKHAISRLGYIGYDQGGVLTEAVRRRP-----YQVILFDEVEKAHPDIFNIMLQILDE--KNTIIVLTSN.................................................................................................................................... 124
7 -13.100PF04665.12; Q6TUP8_YMTV5/6-246; Poxvirus A32 protein  ali follow..  9LLKHPFRIALVGGSGSGKTAYLLSLFNTFV----TPVYNSEYDSYIWPDHVNRVTTYEELDYSLITTKQKIEKYVKKQGNDKTTEMFLLILDDMGDKQIRSSCLLDFLNH---NTSIILLCQTYKHVPVNGRTSITHFCCCNVSDSDIENMLRSMSITGSKKDLLKSVSLMRSVSVNKRRVIIIEDSVFSEGEQRVCYDTADDDVIKNNVNFSILLKQFSHMKKQ............................. 239
8 -11.300PF18748.1; A0A0A0YSQ1_9CAUD/11-206; P-loop Nucleotide Kinase1  ali follow..  17....GELFYVKACNGAGKSTIPSYCAERDPEAYTVSQDGRILLTVMPSYGMLAFGKYDKSKSKGVDSLKDMKKAVELSELEEFIGYTAFFEGV--IPSTILHTWVEYLNRPARPLTTVFIDTDLETCLSRVNSR------AEFNADLVTEKFNRVMSHKTRHK--ELFPSVPAVTIRSQGITIDEMVS.................................................................. 196
9 -11.100PF03215.15; RAD24_YEAST/58-237; Rad17 P-loop domain  ali follow..  45....HRILLLSGPSGCSKSTVIKELSKILVPKYRQNSNGTSFRSTPNEHKVTEFRGDCIVNDLPQMESFS-----GARYLVMSNLSLILIEDLNVFHIDTRRRFQQLILQP-----LVICITECEIPENDNNYR........................................................................................................................ 179
10 -10.800PF06144.13; Q8E0E6_STRA5/20-192; DNA polymerase III, delta subunit  ali follow..  1........VLAGEDLGQYAQMKEKLFQVIG----------------FNKDDLAYSYFDL-SEEDYQNAELDLESL----PFLSDYKVVIFDQFQDITEQAMKRFEAYLQNPVDTTRLVICAPGKRRLVKLLKRDARVLEANTLKESDLKTYFQKQEGLVFEAGVFDELLIKSNYDFSDTLTNIAFL.................................................................... 172
11 -10.700PF07726.11; Q87G66_VIBPA/36-166; ATPase family associated with various cellular activities (AAA)  ali follow..  2.......ILVEGPPGLAKTRAVKSLSDCVEGDFHR---------------TPDLLPADLTGT----DIFRPETGEFTFQSGPIFNSLILADEINRAPAKVQAAMLEAMAEALPELFLVMATQNPIEQEGT............................................................................................................................ 118
12 -10.600PF05621.11; B7J739_ACIF2/21-211; Bacterial TniB protein  ali follow..  10  35....MPNLLIVGDSNNGKTTVIRRFQKLHGEGVNE------------DAEPVPVIVSEAPPSADEKGLIAILERFWTPYRATDHVRILVIDEFHSLLTGTVTKAIKLLCNELAIPIVGVGIREAVRVLHTHASRFDVVTLPPWE.............................................................................................................. 188
13 -10.400PF13604.6; Q3L956_RHOE4/579-769; AAA domain  ali follow..  22........VAVGAAGAGKTTAAKVVARAWEQTNGKVIALGPSAKAADV--------LGAEIDVEGRTIADILTRDQHLATGIEKGDLLLVDEAGMASARNLADLTRIATQSGAVVRLLLASVESGGVLRDLAERTDAPFLSKI............................................................................................................... 154
14 -10.100PF05272.11; Q2FYB7_STAA8/475-664; Virulence-associated protein E  ali follow..  50..KFDYMLTLYGPQGVGKSALLKKLGGAWFSDSLVSVTGKEAYEALQGVWLMEMAELAATRKAEVEAI-----------------KHFISKQVDRFRVA------HYIEDFPRQCIFIGTTNKVDFLRDETGGR........................................................................................................................ 160
15 -9.950PF08298.11; YEAG_ECOLI/19-380; PrkA AAA domain  ali follow..  11  85....KQILYLLGPVGGGKSSLAERLKSLM--LGTIMSPWAAKRLHEFGGDITKFIAKTEPGDENNQDISALVGKVDIRKLCRANQGIMEFVEMFKAPIKVLHPLLTATQE-PFNGIILAHSNESEKNNEAFLDRVYIVKVPYCLRISEEIKIYEKLLNHSELTHAPCAPGTLE................................................................................. 344
16 -9.830PF12169.8; Q11B01_CHESB/247-389; DNA polymerase III subunits gamma and tau domain III  ali follow..  1.................................................................................................................................................................................................VTAETVRDMLGLADRARVIDLFEHLMKG----DVAAALAEYRAQYDAGADPAAVLTDLAEF 57
17 -9.750PF13173.6; F9Z5R0_ODOSD/18-152; AAA domain  ali follow..  2.....KPLILNGARQVGKTWLLHEFAKLE---------------------YKKEAYVVCRKNNLARQLFSQDFNVDTSVDITPGDTLIILDEIQDI--PEALESLKYFKEEVPEYHIAVAGSLLHQDVSYPVGKVNVINIFPMNFEEF.......................................................................................................... 134
18 -9.630PF13401.6; B2UJB3_RALPJ/42-210; AAA domain  ali follow..  4....ESILLVCGPTGAGKTTLAKFMVENIYVQAPASGETKFSWRLFYQRILNQL-RLVRPRGTSGNSLAALRTAVE-RGLRARQVQFMVIDEAAHIFRDTQRNTLKSLVNECGTQIVLVGSYDLYHLV.............................................................................................................................. 169
19 -9.610PF07728.14; Q82S33_NITEU/475-632; AAA domain (dynein-related subfamily)  ali follow..  14  2.......LILQGPPGTGKTWLAKRLAFALMGQKDD--SKVRAVQFHPNLSYEDFVRGWRPTGEGKLSLADFMEAIKAASKDPSSKFVVVIEEINRGNAQIFGELLTLLEAGPENLYVVGTMNIADRSLALVDLALRR..................................................................................................................... 156
20 -9.430PF09848.9; A1A222_BIFAA/236-699; Uncharacterized conserved protein (DUF2075 topsan)  ali follow..  1....SRLIFVQGVAGTGKTVLLSHLFYRIATEMDINGRINDE-QMHVYNQIASKLGLQKHFGEVALKPSQFINRFSIADKPRGKADVVLVDEAHLLLTQG-NMLHDLLRR--------------AKVVIAVFDPNQILQTSQRWSEEDQDML-------FPQQAESDVQKTAAGYSGQLERFVPLNMWGDHYLLSRICLHRQFRIAADDATIRWIDDFADGKR............................... 241
21 -9.330PF01695.17; Y4IQ_SINFN/60-238; IstB-like ATP binding protein  ali follow..  48....GANILLFGPPGGGKSHLAAAIGLAL----------IENGWRVLFTRTTDLVQ----------QVARRELQLESAIAKLDKFDLLILDDL-TKDQAETSVLFELISARYERRSIMITANQPPAMTLAAVDRL....................................................................................................................... 172
22 -9.290PF13245.6; B1YJE6_EXIS2/332-475; AAA domain  ali follow..  12  11....APLMVLTGGPGTGKTTVIKGILHVLVAPTGRAAKRLSEATDVPAMTIHRLLKYDG-------------TNFQLDEDQPIAGKVLIIDESSMIDIYLLSSLLRAVPNGMK----ILFVGDRDQLPSV............................................................................................................................ 142
23 -9.260PF01443.18; RDRP_TMV/829-1085; Viral (Superfamily 1) RNA helicase  ali follow..  10  1.......VLVDGVPGCGKTKEILSRVNFILVPGKQAAEMIRRRANSSGIIVATKDNVKTVDSF----------MMNFGKSTRCQFKRLFIDEGLMLHTGCVNFLVAMSL-----CEIAYVYGDTQQIP.............................................................................................................................. 110
24 -9.130PF01637.18; A8M939_CALMQ/15-228; ATPase domain predominantly from Archaea  ali follow..  20....WNPVVIYGPEGCGKSAFLKQAVEVLG-ESNEKLRYSEELRGLFRDIMTRIPTPFNDASALIDIAISLLYDV--VRRRIRRKIALLADDVFQAGLDKAELLVKRLLNVDYERIVVIVATSEGVTWGRIGRHAEIMAMWNMPREGFGKLY---NALPGPKPPFEEVWRWTGGN............................................................................... 207
25 -9.010PF18751.1; S5Y5G5_9CAUD/1-187; P-loop Nucleotide Kinase3  ali follow..  3....ARLIYLVGQPGSGKSTLMSALTAGFDRHKIAPAPDYPVAHDVLADKTTGEVVGAELGVRGTDALPSSIIDKAAPWVRSQPYPLLLAEGARLANRRFIDAALEGGYEVT--LVLLDHNDAEDWRKVRSKAI------KTQNPSWVKGRLSASRNLALSGPAYEGKAVEVLRGHPDPIRSILKGID.................................................................. 186

FFAS is supported by the NIH grant R01-GM087218-01
1 4 2 0 5 0   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I. and Godzik A Connecting the Protein Structure Universe by Using Sparse Recurring Fragments. Structure (Camb.) (2005) Aug;13(8):1213-24