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Query: gi|108885077|ref|NP_072673.2| methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase (MG_013) [Mycoplasma genitalium G37], from M.genitalium

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSFDGKLKAQSILETYKNFDWSKCKLVIIQANDDDSSDSFIKQKLIACNTVGAKSELIKLSNQITQAELIEKIISLNHDVNVTGIILQLPVYPHLDKNSLLEAINPLKDVDGLTTNHLAEIKPCIVEAIITLKELFNLEFNNQKIVVVGLGITGGKPIYEFLKTSGYKVQACDKDTPNTFELIKSADIVFTAIGKSHFFQAKNFKKGVILFDIGVSRNKQNKLCGDINPEGIEKKARWWTKTPGGVGPFTVLAIIKNLWILHEKNKRCLQSSILast
1 -66.800d4cjxa2 c.2.1.0 (A:125-297) automated matches {Trypanosoma brucei [TaxId: 999953]}  ali model 3D-neighbors follow..  26  1................................................................................................................LLPVNVGQLVPCTASAVMELLRCSGVEICGKRVVVLGRGDIAGLPVATLLANEDATVTVVHSATCDIADIVRASDIVVSAAGQPGLVRGEWIKLGAAVIDVGTTPVADPRLVGDVCFDVARKRAAYITPVPGGVGPVTVSMLLKNTLTMFKRSVR...... 172
2 -64.900d4b4ua2 c.2.1.0 (A:122-282) automated matches {Acinetobacter baumannii [TaxId: 575584]}  ali model 3D-neighbors follow..  31  1................................................................................................................VTCLGFGRMGSATPAGIMTILKENNIEIAGKHAVVVGRSAILGKPMAMMLLQANATVTICHSRTQNLPELVKQADIIVGAVGKAELIQKDWIKQGAVVVDAGFHPR-DGGGVGDIQLQGIEEIASAYTPVPGGVGPMTITTLIRQTVEAAEKALG...... 161
3 -61.500d3ngxa2 c.2.1.0 (A:116-276) automated matches {Thermoplasma acidophilum [TaxId: 2303]}  ali model 3D-neighbors follow..  25  1................................................................................................................LSPYNQGLIVPATPRAVIDIMDYYGYH--ENTVTIVNRSPVVGRPLSMMLLNRNYTVSVCHSKTKDIGSMTRSSKIVVVAVGRPGFLNREMVTPGSVVIDVGINYV-NDKVVGDANFEDLSEYVEAITPVPGGVGPITATNILENVVKAAEFQKN...... 159
4 -52.700d1edza1 c.2.1.7 (A:149-319) Methylenetetrahydrofolate dehydrogenase/cyclohydrolase {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  17  1..........................................................................................................................PCTPLAIVKILEFLKIRLYGKKCIVINRSEIVGRPLAALLANDGATVYSVDVNEDLLKKCSLDSDVVITGVPSENYFPTEYIKEGAVCINFAC---------TKNFSDDVKEKASLYVPMTGKV---TIAMLLRNMLRLVRNVELSKE... 171
5 -50.400d4b4ua1 c.58.1.0 (A:1-121) automated matches {Acinetobacter baumannii [TaxId: 575584]}  ali model 3D-neighbors follow..  33  3LVLDGRALAKQIEENLLVRVGRTPILATILVGDDGASATYVRMKGNACRRVGMDSLKIELPQETTTEQLLAEIEKLNANPDVHGILLQHPVPAQIDERACFDAISLAKDVDG................................................................................................................................................................. 121
6 -49.900d4cjxa1 c.58.1.0 (A:1-124) automated matches {Trypanosoma brucei [TaxId: 999953]}  ali model 3D-neighbors follow..  27  5VVIDGRAVAKAIQKELTEEVGRRPGLSTIICGKRKDSQTYVRLKRKAAAACGFRNFSVELPANVTQEALEREVIRLNEEEACHSIVVQLPLPPHIDKVAALSKIKPEKDAD.................................................................................................................................................................. 123
7 -49.300d1edza2 c.58.1.2 (A:3-148) Tetrahydrofolate dehydrogenase/cyclohydrolase {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  20  5.TILASKVAETFNTEIINNVGQGPLLVGFLANNDPAAKMYATWTQKTSESMGFRYD---LRVIEDKDFLEEAIIQANGDDSVNGIMVYFPVFGNAQDQYLQQVVCKEKDVEGLNHVYYQNLYKENRLKSI............................................................................................................................................... 145
8 -48.400d1a4ia2 c.58.1.2 (A:2-126) Tetrahydrofolate dehydrogenase/cyclohydrolase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  35  5.ILNGKEISAQIRARLKNQVGFTPRLAILQVGNRDDSNLYINVKLKAAEEIGIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSEINTEEVINAIAPEKDVDG................................................................................................................................................................. 125
9 -47.500d3ngxa1 c.58.1.0 (A:2-115) automated matches {Thermoplasma acidophilum [TaxId: 2303]}  ali model 3D-neighbors follow..  21  2.ILRGEEIAEKKAENLHGIIGLEPSLKLIQIGDNEAASIYARAKIRRGKKIGIAVDL-EKYDDISMKDLLKRIDDLAKDPQINGIMIENPLPKGFDYYEIVRNIPYYKDVDA................................................................................................................................................................. 114
10 -13.400d1li4a1 c.2.1.4 (A:190-352) S-adenosylhomocystein hydrolase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  17  2.......................................................................................................................NLYGCRESLIDGIKRATDVMIAGKVAVVAGYGD-VGKGCAQALRGFGARVIITEIEVTTMDEACQEGNIFVTTTGCIDIILGRQMKDDAIVCNIG-------HFDVEIDVKWLNENAVEKVNIKPQVDRYR....................... 140
11 -9.730d2pv7a2 c.2.1.6 (A:92-243) Prephenate dehydrogenase TyrA {Haemophilus influenzae [TaxId: 727]}  ali model 3D-neighbors follow..  14  5.........................................................................................................................................INSDIHKIVIVGGYGKLGGLFARYLRASGYPISILDREDWAVESILANADVVIVSVPINLTLEKPYLTENMLLADLTSVKREPLAKMLEVHTGAVLGLHPMFGADIASMAKQVVVRC................... 127
12 -9.090d4r3na1 c.2.1.3 (A:2-127,A:330-358) Aspartate beta-semialdehyde dehydrogenase {Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]}  ali model 3D-neighbors follow..  13  1.............................................................................................................................................GYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASA-ETAFEGVDIALFSASTSAKYAPYAVKAGVVVVDNTSYFRQNPDVVPEVNAHALDAHNGIIA--PNIAETLHERGLVRPTAELKFELK....... 156

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Veeramalai M, Ye Y, Godzik A. TOPS++FATCAT: fast flexible structural alignment using constraints derived from TOPS+ Strings Model. BMC Bioinformatics. 2008 Aug 31;9(1):35