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Query: gi|13507748|ref|NP_109697.1| hydrolase MPN009 [Mycoplasma pneumoniae M129], from M.pneumoniae

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MEYFDAHCHLNCEPLLEQHEKSLANFRLIGLKANVVGTNLTNSQIAVNLAKQHPDLLKAGVGIHPNDVQLFDLKAAQATLKKLVSTHRSFISCIGEYGFDYHYTKDYITQQEQFFLMQFQLAEQYQLVHMLHVRDVHERIYEVLKRLKPKQPVVFHCFSEDTNTALKLLTLREVGLKVYFSIPGIVTFKNAKNLQAALSVIPTELLLSETDSPYLAPVPFRGKTNWPECVVHTVQTIADIKQVPLAEIKQAIVHNAKKLFWLast
1 -108.000[L] COG0084 Mg-dependent DNase  ali follow..  26  1MQIFDTHAHIGLIHPDPERLRVVQEARRASVTRIMICNSLHDFAAVYETLQFSPS-VYHAVGVSPSEVMAPG-KDWIDTIQKSLQLPQ--VVALGETGLDYCKKYGDKRSQIGLFITQLDIASKAKKPVIIHNRGAGQDILDILSERIPDQGGVFHCYSEDAEYARMALD-----LPVYFSFAGNLTYRNARNLHETVLALPLDRILVESESPFMSPATYRNKRNRPAHTVETVEFMAELLDMDMLELADQLWKNSCACFH 254
2 -82.000[L] KOG3020 TatD-related DNase  ali follow..  22  139VPYIDSHCHTDYNEGLLDWIEKYPRAFPKCFFGLIAGNSSYDVEWIVKELASPLY-LGTTWGCHPHFAQHWGRMGTMEYILSDAEEWK--VLAVGECGIDLHRCESELEVQKDVFEKHVALAFKFKLPLVIHCRNAEEECLQILKKKMDVLKIHRHCFTENWEVAQMWLK---QCPDVHFGFTPAVFTMGA-PQIQAIRNIPLDRILLETDGPYFKPKCYDGKVCLPGMAIATASKIAEIKNLPIEEVLRATFNNTRRVYQ 433
3 -65.700[R] COG1099 Predicted metal-dependent hydrolases with the TIM-barrel fold  ali follow..  15  2..YFDSHLHSEGLGFSE-----LVKLKENGIKEVCLAFFPVKPKYPQTMIDVFRKLMHPAVGIHPRCIPP-----DYEFVLGYLEEGE--WVAFGEIGLELVT-----DEEIEVLKSQLELAKRMDVPCIIHTPKATRKTLEILESLDFP-ADLAVIDHVNFETLDMVLE-----TEYWIGLTVQPGKLSAEDAARIVAEHGPERFMLNSDAGY--------RDVEITTVAEAAVKIEE--AVGREEMEKVARENARKFLR 247
4 -61.600[R] COG1831 Predicted metal-dependent hydrolase (urease superfamily)  ali follow..  18  1MIILDNHFHVD--PINGLFLEAVKQFHRAGGTHLVVYKSAHDYGFGGMKGEDFMRAAYAVVGVHPAEFDYLARARGIEYAKREVMKLDGKAIGIGEVGRPHYPPEEIWEASIEIMKYAMALAKEADCAVQLHTESFDEEKFRELREVGIKPYRVVKHFSPP-------LVKVAEEVGIFPSI-----IASRKNIEEAIKQGT--RFLMETDYIDDKRRP--GAVLGPKTVPRRTKELLQKGILTEDDVYRIHVENPEKVYG 276
5 -17.100[R] KOG4245 Predicted metal-dependent hydrolase of the TIM-barrel fold  ali follow..  12  12SRKIDVHAHVLPKNIPDDTETRIADMNRANVNVQCLSTVPVKPADTEIVARFVNDDLLAECQKFPDRLVPLGTLPMNDV--QRAVEEVKRCVSMGIKGFEVGSHVAEKSLDHRDFWPLYKICEELSVVLFVH--VLFPKLKLCFAHGGGAYPQIRHGWNVRPDLCAGKCKVAPNKLDGLLWTDSLVH--DPKALELLINTVGKEHIVLGTDYPF------------PLGELEVGRVVEEYKPFSAKDREDLLWKNAVKMLD 341
6 -13.400[R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold  ali follow..  15  2..IIDTHLHLGVPALDRDFATYAAEAKRVGVAASLHAEIELETREVARLAGEPGSLLKGAIA------CRPEDEGFAAYLERQEENAFVK-------GFRRVLHVVTDDSEQPLFRENVKRLSGTRFTFDLCVLPHQIPKAIALADLAPDVQFILHC-GHAEHPWRDHMTEIARHPNVVAKISGVVAYAEED-VEHTISVFGWDRVVWGSDWPVCT---------GGNLSTWVAATQALIEGCSPQERRKLLSGNAQRIWN 276
7 -13.300[R] COG1735 Predicted metal-dependent hydrolase with the TIM-barrel fold  ali follow..  13  89....................AELKDFVAAGGQTVVEPTCQRNPLAMRRISQATGLNIVMGAGYYPEKVAGLTVDAIADEIQEARHGVDGTDVRIGLIGE----SADFTAAEEKSLRGAAQAHVRTGLPLMVHLLRLGHRVLDVVAEEGADLNHTVLCHMNPSHADIAYQ-SELAGRGAFIEYDMI-DEDAARSIVTLVEGGYLDRILLSHDVFLKMMLTRYGGNGYAYILKHFLPRLKR-HGLDDVTLQTLMRDNPRSVF. 351
8 -12.500[F] KOG2902 Dihydroorotase  ali follow..  13  8..LADMHVHLRQD---NMLKAVVPTVAEGGVSVAYVMPNLIPPITTVDACLQYKKEIEQL-------DSKTTYLMSLYLSPETTPEVIYEAAKKGIRGVKSYPKGATTNESYEPFYPTFAAMQETGMILNIHGEVFLPTLLDLHQRFPKLKIVLEHC---TTADAVEAVKACGESVAGTITAHHLYLTQKDWQDDPYCFCKPVAK-FFGSDS---APHPRSSKLKTPP-QPFAASYLAEVKEGRLDALKDFACIFGRKFYC 294
9 -12.500[F] COG0418 Dihydroorotase  ali follow..  10  9..PDDWHLHLRDGAALKAVLPHTVRQFARAIVMPNLKPPVRSVADAAAYRERILAAIPAGGQFEPLMTLYLTDNTNPEEIIAAKA--SQFVKAVKYYPAGATTNSDFGVTDIHRCDAVLAAMEQVDLPLLLHGEVTDSNLIPLREKFPRLRVVLEHITTDAVQFVLSANNIAATITPQHLLFS-LKREEHRLSLLHAATSGNPKFFLGTDSAPHARNSK--GCYSALHAMELYAEAFES--VNSLDKLEAFASFYGPDFYQ 300
10 -11.200[R] COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold  ali follow..  11  7LFIVDSDCHNYWCSATNYAIMKEKHLDKYNIDVAILTGDLANAHYANALCRAYNDYMIDYWLPKDSRVAPQDPKLAAEEIRRLGSHPRIVQVLVSHGA--------QRPYGDPFYHPIYEACAEMGLPFAMHL-SAMTHMASLI------AQGVFEKWECGVAWVPSVLWRLDANYKALRKETPWLKRLPSEYFKTLEAMDGENTLLFASDYPH--------------------YDDVTKLHIPPAWREKVLGLNALDVYR 355
11 -10.800[F] COG0044 Dihydroorotase and related cyclic amidohydrolases  ali follow..  10  119..RTDYSFHIAITGWNERTFNEMVEVVKRGINTFKHFMAYKGNDDEMFASFQRCAELGAMPLVHAEN-------------GDIVAQLQAKLMAEGNDGPEAHAYSRPPEVEGEATNRAIMIADQAGVPLYVVHVSCEQSHEAIRRARQKGIRVFGEPLIQHLTLDESEYHNRDWDYAARRVMSPPF--RDKLNQDSLWAGLAAGSLCVATDCAFTTEQKRYGIGN-EERMPVLWTRGVRTGRLTPNEFVAVTSTNIAKILN 378
12 -10.100[F] KOG2584 Dihydroorotase and related enzymes  ali follow..  10  70...VDVHTRLQMPTPADDFCQGTKAALAGGTTMILDHVFPDTGVSLLAAYERWDSAACCDYSLH-KDRCQCSDSQMYEIFSDIVEEEQKRLLELGITGPEGHVLSHPEEVEAEAVYRAVTIAKQANCPLVTKV--MSKGAADAIAQAKRRGVVVF-ITASLGTDGSHYWSKNWAKAAAFVTSPPVN--PDPTTADHLTCLLSSGDLVTGSACTFTTAQKAVGKDN-EERMSMVWEKCVASGKMDENEFVAVTSTNAAKIFN 393
13 -9.030[F] COG1001 Adenine deaminase  ali follow..  11  82..FIDTHLHIESSLVTP--HEFDRCVLPYGVTTAICDLGAEGLQFFLDSAMETIMDIRVQLSSCVPATHLETSGADLPIEKLLPFRNHPKVIGLAEF-MNFPGVIHKDPVCMA------KLEAFQGQHIDGHAPLLSGAALNGYLAAG---------IRTEHECTSAAEALEKIRKGMHILVREGSVSKDLHALMPIITERLSPYLALCTDDRNPLDIAEQGHLDY-------MIRTAIASGVEPLAIYRAASISAAKAFG 322
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 4 6 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.