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Query: gi|13507755|ref|NP_109704.1| ribosomal S6 modification protein MPN016 [Mycoplasma pneumoniae M129], from M.pneumoniae

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKHISAVYNPAFTNIASKLNQTELLKDAAQSLNIQLDFFTCFDINTNQDKTKLPFKSNTILFLDKNIALAQWLESVGLRVINSSIAINNADNKALSHAVLAQHPTIKQIPTLIGPQNFRLAWYPEKLEQFIEQIKRCFQFPVIVKSIYGSFGDYVFLCKDEQKLRQTLSGLTEQIIVQQYIATSNSEAVRVIVVNNQVVGALHTQNEGDFRSNLNKGAVGEPYQLSQEETKLAITISQAMQLFYCGIDFLFDQDRSLIFCEVNSNVQLTKSSMYLKTNLAIQLLASIALast
1 -54.000[HJ] COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)  ali follow..  19  24MRIAFFV---NSIETEGPTFATGLLAMAALNRGHDVVYLTPGDFTLRSDDTLAVHATDALMLRHAGILFGRLAEQRGVVVLNDPEGLALAQNKLYFQSF----PEIVRPTTLISRNV-----------EEIRAFADTHPKGVIVKPLQGSGGKNVFKIGSSKETNFEAVSLEGYLIAQAYLPAAKEGDVRFFMMNGRPLMRDGQYAKGDLRSNIHANGTAEAVKVTDEIVELAEMMRPKLGMFLVGLDIV---GDKILEVNVFSPGGLSNILELTNVDFSDTIIEAVE 350
2 -25.400[R] COG1821 Predicted ATP-utilizing enzyme (ATP-grasp superfamily)  ali follow..  14  55.................PVDSMDSMEKYLEKSDAFLIIAPEDDFLL--------------------YTLTKKAEKYCENLGSSSRAIAVTSDKWELYKKLRG--EVQVPQTSLRP----------------------LDCKFIIKPRTACAGEGIGFSDEVPD----------GHIAQEFIE---GINLSVSLAVGE-CLSVNEQIINNFRYAGAVVPARISDEVKREVVEEAVRAVECVENGYVGVDIVY--SDQPYVIEINATTPVVAFSRAYGASVADLLAGGEV 272
3 -23.100[R] COG3919 Predicted ATP-grasp enzyme  ali follow..  12  1MTIPGVVIIGGAHGT--------ALARSLGVLNVPVYYLTHDSPLPGWSRAEKPGLKGCLLVPSGDGEVQEELSALYKIILPEWTNLQWLCEKPLLYKRAAELG-VSIPRTYAL-------------TSAADIDGLDVMFPVILKPHMGGGNTSVIRADDREELKAAFVDASGNVVVQELIP---GGGESQFSYNGEPIAEFTARRARQYPVDFGYTSTRVEVVDNRQAIEAARKILKSAGSGLVEVEFKLDRDGALKLLDVNPRPSWFGLCSAAGINLGGLLWRVAN 311
4 -22.900[M] COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes  ali follow..  14  1MKIA-VLYGGTSAEREVSLSSGKGIMEALKANGHEVIGIDFHPDQVRDLVDLDVDLVFIGLH-GEDGKVQALLDLLNIPYVGTVQGSALAMDKAKAKLFFEKAG-IRVAEEVVLHSF----------TYDANAFNFTGTYPVVVKPNQEGSTIGLTVAETEEELLQGIERHDDTILIEEFIA---GTEVTVAVLGNKVVEIVPKNKLYDYESKYAPGMSEHIVEHTAYVQQAAVRAHQALGCVYSRVDFIVPNDGDPVILKVNTLPGMTPTSKGVGMSYEEMIQTFVN 300
5 -22.600[TU] KOG3895 Synaptic vesicle protein Synapsin  ali follow..  13  90..FTLLVLDDQNTD--------SKYFRGRRLHGIRVEQAEFRDITVVSSADT-SFRPDFVLIRQP--STILGLKYGGVPSINSLHSIYQFQDKPWVFSHLLQRDGFPLIEQTFFPNPRDLVSIRETFFLSVHLQFQFTKFPSVLKAGHCHGGVATARLENQSALQDAAGLVHCYCTIEPYIDAK--FSVHIQKIGNNYKAFMRKSITGNWKTNQG-SAMLEQITLTEKYKSWVDEISELFGMEVCGLSVVVAKDGREYIISACDST-IGDTQEEDRRQIADLVSGRMQ 452
6 -20.800[R] COG2232 Predicted ATP-dependent carboligase related to biotin carboxylase  ali follow..  12  4MEEILVI-----------GVNTRPVVESAFRLGYRVYSAGCGRFHENFSQEKLLEAASDFIERADGIIPLTGAPPLPGEKVLGNSRVDHVEDKYRLYRRIRN--SYPTPETHLISDPAEAMEIVAA-----------GEKKYIAKPVSGAGGFGVTEFREGDG----------EFLLQEYIEGVP--SASVLSTGEDAITVLTSRQIIDRGVPGFEGQFVYAGNMTGEIEDLASDLILDLSLGSNGVDLIMRDSE-LYVIEVNPQGTFECAEASLGINMVDAHIRACM 286
7 -20.600[F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase)  ali follow..  13  25......................KEVVIELQRLGVEVIAVDRYANAPAQQVAHRAYTISML-VEAIATATLVELEQAGFTVIPTAKATQLTMNREGIRRLAAEELGLPTSNYQFVDN-----------FDDFKRAVEKIGIPCVVKPIMSSSGHGQSILKSVEQIPSAWEYAQQRVIVEGFVKFD--YEITLLTVHGTSFLAPIGHIQIDGDYRESWQPQAMSAVALEKAQAIAEKITGALGRGIFGVEMFVCGDE-VIFNEVSPRPHDTGTLISQELSEFALHARAIL 308
8 -19.100[R] COG1759 ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases)  ali follow..  9  113......................................................................RVENEFLVPMFRSLLRTEERSEEKSYYWLLEKAK-LPYPEPVSP-----------------EEIDDVGLVIVKLPHAKKRLERGFFTAASYKEFKEKSEKLIRKARIERYIIGPVDGEIELLGIDAAQQLTLPEWQFEPEYTVCGHASSTLRESLLEKVFDMAEKYVEATKKGIIGLQTAVDKDLNFYIYDVAPRGGGTNIHMAMGHPYGNSLWR... 353
9 -18.300[I] COG0439 Biotin carboxylase  ali follow..  17  84.............................................................FMAENPDFAEMCREHGIVFIGTPESMRALGSKAGGREIAAQSNVPTVPGT-----------GVLESVDAALLAAKQIGYPVLLKASAGGGGRGQKVIRTQEELQKGFNQAQEEIIMEKFLEEFRHIEVQVM---GHVIHIGERDCSIQRRNQIEEAPSTLPESLRQEILAAGVRLAQFVNYAGAGLEFIMDRDGNYYFMEMNTRIQVEHSEMISSLDLVRLQIEIAA 315
10 -17.400[F] COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase)  ali follow..  13  24......................RMLAMAAARLNHRTIVLEPQEYDDEKALAELASRCDVVTYEFENVPVAAAEKLSAVPVYPPAQALSASQDRLTEKRFLNGCG-IPTADFRAVDS-----------QDELEAALTAFGGKGVLKTRRGYDGKGQRLFRGGENLTGAFAALGGPLILESFVAFE--REISIIAAGTVTCYDPAENVHLNGILHTSTVPAALSDAAKAVAVQSAEKLLAALEVGVIGIEFFVLPDGSLVANEMAPRVHNTGTEAACAISQFEQHIRAVS 300
11 -17.300[I] COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit  ali follow..  13  15.......................RIIRACRDYGLQSVAVDQDALFVRLADEAYALEGVRPAFLSERAEFAQAVIDAGLIWIGDPDVIEALGDKVMARRIATGVGAPLVAGS----------DGPVSSAAEVTAFAEQHGLPVAIKAAHGGGGRGLKVAWKMEEIAELYESAVRECFLERFLDRPRHIEAQVI---GNVLVLGTRDCSLQRRNQ-EAPAPFLSDEQRQKIHDAAKAICAAAGYSGAGVEFLLGVDGTISFLEVNTRLQVEHTEETTGIDLVIEQFRIAE 316
12 -16.600[EF] COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)  ali follow..  13  7IQKIMVIGSGPIIQAAEFDYAGTQACLSLKEEGYEVVLVNSNPATIMTDKEIPTLGGQTGLNMAMELSKNGILDELGVELLGKLSAIDQAEDRDLFKQLMEELE-QPIPESEIVNTV-----------EEAVAFAATIGYPVIVRPAFTLGGTGGGMCANEKELREITENGVTQCLIERSIAGFKEIEYEV-MRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQQMLRDASLSIIRALKIGGCNVQLLDPNSFKYYVIEVNPRVSRSSASKATGYPIAKLAAKIAV 327
13 -15.300[IE] KOG0238 3-Methylcrotonyl-CoA carboxylase, biotin-containing subunit/Propionyl-CoA carboxylase, alpha chain/Acetyl-CoA carboxylase, biotin carboxylase subunit  ali follow..  16  63.......................RVIKTARAMGIKTVAVHSDV----APTAKSYLRADRILFLSENTKFAAELEKAGAKFIGNSKAILDMGDKIHSKKIATAARVSMIP-----------YDGEIADEDMCVKVSRDIGYPVMIKASAGGGGKGMRVAWNDKQAREGYRLSKQEMLVEKFIDNPRHIEMQVL---GNALWLNERECSIQRRNQ-EAPSSFVPPEMRRKMGEQAVQLAKAVGYDSAGVEFLVDSQRNFYFLEMNTRLQVEHTECITGIDIVQQMLRVSY 364
14 -14.800[C] COG1038 Pyruvate carboxylase  ali follow..  12  91....................SIEEVIRVAKLSGADA-------------------------LLSESPEFVEACNKAGITFIGTPDTMRQLGNKVAARNLAISVDVPVVPAT----------NPLPDDIAEVERMAEEIGYPVMLKASWGGGGRGMRAIRKKEDLAREVTEAKREVYLEKLVERARHVESQIL---GNVVHLFERDCSIQRRNQ-RAPAPYLSEAQRQELAAYSLKIAAATNYIGAGVEYLMDADGKFYFIEVNPRIQVEHTEVVTGIDIVKAQIHILE 347
15 -13.800[O] KOG2158 Tubulin-tyrosine ligase-related protein  ali follow..  15  199................................................................................INHFPGMIEICRKDLLSRNLNRMLKI-FPKTWMLPADY----------GDAMNYALNHKRTFILKPDSGAQGRGIWLTNDLKTIGP-----HERLICQTYIHRPYKFDLRVYTL------GLARFATNKYVTNYSVNKRNSHYEFWSNVDDVIIKTVLSAWFEILGFDILVDWKLKPYILEVNHSPSF-HTNEQVDREVKRPLIRDT. 471
16 -13.300[F] KOG2835 Phosphoribosylamidoimidazole-succinocarboxamide synthase  ali follow..  14  16......................RMIVEAANRLNIKTVILDAENSPANPLDIEKLAEKCDVLTIEIEHVDVPTLKHPKLKIYPSPETIRLIQDKYIQKEHLIKNG-IAVTQSVPVE---------QASETSLLNVGRDLGFPFVLKSRTAYDGRGNFVVKNKEMIPEALEVLDRPLYAEKWAPFT--KELAVMIVGLVFSYPIVETIHKDNICDLCYAPARVPDSVQLKAKLLAENAIKSFPCGIFGVEMFYLETGELLINEIAPRPHNSGTIDACVTSQFEAHLRSIL 298
17 -13.300[F] COG0151 Phosphoribosylamine-glycine ligase  ali follow..  14  54......................PALVKFAQDKQIGLTIVGPEAPLVI---------------------VVDAFREAGLKIFGAKAAAQLEGSKAFTKDFLARHK-IPTAEYQNFTEVEPALTYLRE-----------KGTPIVVKADGLAAGKGVIVAMTLQEAEDAVRDMGSRVVIEEFLD---GEEASFIVMDGKNVEPMKRVGENDTGLNT--GGMGAYSPAPVITPEIHSRIMKEVGNVYTGFGLMIMPNGQPKVIEFNGDPETQPIMLRLKSDLVELCLKACD 316
18 -13.000[O] KOG2157 Predicted tubulin-tyrosine ligase  ali follow..  17  270................................................................................VNHFPRSYEMTRKDRLYKNIERMQHL-VPQTFVLPIES----------RDLVVAHNKHRGPWIVKPAASSRGRGIFIVNSPDQIPQ-----DEQAVVSKYIVDPHKCDLRVYVL------GIVRLATVKYDCNYSINKYHSDYQLMLNIEDLIIKAVLACAFELYGFDILIDNALKPWLLEINLSPSM-GVDSPLDTKVKSCLMADL. 542
19 -11.500[F] KOG0237 Glycinamide ribonucleotide synthetase (GARS)/Aminoimidazole ribonucleotide synthetase (AIRS)  ali follow..  14  60......................EQLVKFALDKDVNLVIPGPELPLVE---------------------IEGHFRRVGIPCFGSALAARMEGSKVFSKDFMHRNN-IPTAVYKSFSNYDHAKSFLDT-----------CTFDVVIKADGLAAGKGVIIPKTKKEAFEALESIGKNVVIEELLE---GEELSILTFDGYTCRSLKRAFDGDKGPNT--GGMGCYAPTPVASPKLLETVQSTIGYPLVGIGLMLTPSG-PRVLEYNGDPETQAVLPLLESDLAEIILACVN 321
20 -11.100[E] COG0754 Glutathionylspermidine synthase  ali follow..  17  181.............DTVEDRGTIQYLQDCAAEAEIATEFLYIDDIGLGEKGQFTDLQDQVILFKLYPWEFSTKLEDAGVRWLEPAWKS-IISNK----ALLPLLWEMFPDHPNLLPAYFAEDEHPPMDK-------------YVVKPIFSREGANVSIIENGKTIEVEGPYGEEGMIVQQFYPLPKFGDSYSWLINDQPAGIGIREDRALITQDLS......................................................................... 377
21 -9.820[S] COG2308 Uncharacterized conserved protein  ali follow..  13  286....................NSAYYEHAYLARLMGVPLVEGRDLVVHENRTTTGLRRIDVIYRRVDDDLFNAYRAGNVVICNAPGT-GVADDKAVYAYVPDIIRYYLGEDAILPNIETYLCREPRQLSHVLANLDK-----LVVKAVGASGGYGMLV-KERDDFALAIKADPENYIAQPTIQEPRHVDLRPFILSGETPGALTRVARGSLVVNSSQGGGSKDTWVLADDAPSNGNGHGS................................................. 542
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Topczewski J, Godzik A., Paszewski A. The Aspergillus nidulans cysA gene encodes a novel type of serine O-acetyltransferase which is homologous to homoserine O-acetyltransferases. Microbiology. 2000 Oct;146 ( Pt 10):2695-703.