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Query: gi|13507743|ref|NP_109692.1| DNA gyrase subunit A MPN004 [Mycoplasma pneumoniae M129], from M.pneumoniae

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAKQQDQIDKIRQELAQSAIKNISLSSELERSFMEYAMSVIVARALPDARDGLKPVHRRVLYGAYTGGMHHDRPFKKSARIVGDVMSKFHPHGDMAIYDTMSRMAQDFSLRYLLIDGHGNFGSIDGDRPAAQRYTEARLSKLAGELLRDIDKDTVDFVANYDGEEQEPTVLPAAFPNLLANGSSGIAVGMSTSIPSHNLSELIQGLILLIDNPDCTINDLLGVIKGPDFPTGANIIYTKGIESYFETGKGNVVIRSKVSIEQLPTRAALVVTEIPYMVNKTSLIEKIVELVKAEEITGIADIRDESSREGIRLVIEVKRDTVPEVLLNQLFKSTRLQVRFPVNMLALVKGAPKLLNMKQALTVYLEHQLDVLIRKTQFNLKKYQERFHILSGLLIAALNIDEVIAIIKKSANNQVAMEALHERFGLDEIQARAVLDMRLRSLSVLEVNKLQTEQQELKALIEFCQQVLADKQLQLKLIKEQLTKINEQFGDPRRSEILYGISEDIDDEDLITQENVVITMSTNGYLKRIGVDAYNLQHRGGVGVKGLTTYTDDSISQLLVCSTHSDLLFFTDKGKVYRIRAHQIPPGFRTNKGIPAVNLIKIDKDEKICALISVNDYQNGYFFFCTKNGTIKRTSLSEFANILSIGKRAILFKENDVLFSVIRTSGQDDIFIGSTAGFVVRFHEDTVRPLSRAAMGVLGINLNQCEFVNGLSTSSNGSLLLSVGQNGIGKLTSIDKYRLTKRNAKGVKTLRVTAKTGPVVTTTTVFGNEDLLMISSAGKIVRISLEQLSEQRKNTSGVKLIKLKEKERLETVTIFKKEEAIKTTTATETDDVGSKQITQLast
1 -124.0001zvu_A mol:protein length:716 Topoisomerase IV subunit A  ali model follow..  31  1.........................................MDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAIITSRAEIRKIYENGRGSVRMRAVWKKED----GAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGLGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPA---LMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQEREAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDI--------DAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPS--ARGQGEPLTGKLTLPPGATVDHML--MESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIDASDMLLAITQAGRMLMFPVSDLPQLSK-GKGNKIINIPSAEAARGEDGLPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEIDS............................................................................. 715
2 -120.0004i3h_A mol:protein length:1144 Topoisomerase IV subunit B, DNA topoisomerase 4 subunit A chimera  ali model follow..  42  633IEDNVKFTLEEATVFHMSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMHGNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFPNLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVVVRSKTEIEKLKGKEQIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDNFTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALIRASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAIIGDERTMYNLMKKELREVKKKFATPRLSSLED.................................................................................................................................................................................................................................................................................................................................................... 1132
3 -117.0002xcs_B mol:protein length:692 DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A  ali model follow..  55  191IEDNAVYANLDFAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRFTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEEGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQL.................................................................................................................................................................................................................................................................................................................................................... 691
4 -116.0002xco_A mol:protein length:726 DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A  ali model follow..  56  225IEDNAVYANLDFAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEEGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELETILADEEVLLQLVRDELTEIRDRFGDDRRTEIQL.................................................................................................................................................................................................................................................................................................................................................... 725
5 -116.0002inr_A mol:protein length:514 DNA topoisomerase 4 subunit A  ali model follow..  45  1MGSSSSGPRGSHMLEVSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDSSVYEAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFIPNYDDTTLEPMVLPSRFPNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVRSKVEEETLRGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNSDLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIELIRSSKNKRDAKENLIEVYEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERLSLIEA.................................................................................................................................................................................................................................................................................................................................................... 502
6 -116.0003nuh_A mol:protein length:525 DNA gyrase subunit A  ali model follow..  51  2.............SDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITA.................................................................................................................................................................................................................................................................................................................................................... 523
7 -116.0004ddq_A mol:protein length:502 DNA gyrase subunit A  ali model follow..  53  2............SEQNTPQVREINISQEMRTSFLDYAMSVIVSRALPDVRDGLKPVHRRILYAMNDLGMTSDKPYKKSARIVGEVIGKYHPHGDSAVYESMVRMAQDFNYRYMLVDGHGNFGSVDGDSAAAMRYTEARMSKISMEILRDITKDTIDYQDNYDGSEREPVVMPSRFPNLLVNGAAGIAVGMATNIPPHQLGEIIDGVLAVSENPDITIPELMEVIPGPDFPTAGQILGRSGIRKAYESGRGSITIRAKAEIEQTSGKERIIVTELPYQVNKAKLIEKIADLVRDKKIEGITDLRDESDRTGMRIVIEIRRDANANVILNNLYKQTALQTSFGINLLALVDGQPKVLTLKQCLEHYLDHQKVVIRRRTAYELRKAEARAHILEGLRVALDHLDAVISLIRNSQTAEIARTGLIEQFSLTEKQAQAILDMRLQRLTGLEREKIEEEYQSLVKLIAELKDILANEYKVLEIIREELTEIKERFNDERRTEIVTSGLETIEDEDLIE....................................................................................................................................................................................................................................................................................................................................... 502
8 -115.0004z2c_A mol:protein length:499 DNA gyrase subunit A  ali model follow..  54  2...............QDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVDGHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPARFPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTGALVMGKSGIHKAYETGKGSIVLRSRTEIETTKGRERIVVTEFPYMVNKTKVHEHIVRLVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAIQNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIRIIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIADLADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQILSLE............................................................................................................................................................................................................................................................................................................................................. 493
9 -114.0003ifz_A mol:protein length:508 DNA gyrase subunit A  ali model follow..  47  1MTDTTLP-----PDDSLDRIEPVDIEQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMFDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDSLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYTEARLTPLAMEMLREIDEETVDFIPNYDGRVQEPTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDATLAAVMGRVKGPDFPTAGLIVGSQGTADAYKTGRGSIRMRGVVEVEESRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLDQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALERQRIIDDLAKIEAEIADLEDILAKPERQRGIVRDELAEIVDRHGDDRRTRIIA.................................................................................................................................................................................................................................................................................................................................................... 500
10 -110.0006bq9_A mol:protein length:496 DNA topoisomerase 4 subunit A  ali model follow..  41  1.....SNAMSDSLELSLDGVERRSLADFTEQAYLNYSMYVIMDRALPHIGDGLKPVQRRIVYAMSELGLDADAKHKKSARTVGDVLGKFHPHGDSACYEAMVLMAQPFSYRYTLVDGQGNWGAPDPKSFAAMRYTEARLSRYAEVLLSEVGQGTVDWVPNFDGTLQEPAVLPARLPNILLNGTTGIAVGMATDVPPHNLREVASACVRLLDEPKATIEQLCEHIQGPDYPTEAIVTPRAEILKMYESGRGSIRMRAVYRVE----DGDIVVTALPHQVSGAKVLEQIAAQMQAKKLPMVADLRDESDHENPCRIVIIPRSNDVDELMQHLFATTDLESTYRVNVNIIGLDRPQLKNLRTLLVEWLEFRTNTVRRRLQHRLDKVEKRLHLLDGLLTAFLNLDEVIHIIRTEEY---PKQALIERFELTEIQADYILETRLRQLARLEEMKIRGEQDELLKEQAKLQALLGSEAKLRKLVRSELIKDAETYGDDRRSPIVA.................................................................................................................................................................................................................................................................................................................................................... 492
11 -108.0003lpx_A mol:protein length:500 DNA gyrase, A subunit  ali model follow..  50  2...........................................RALPDVRDGLKPVHRRVLFAMDVLGNDWNKAYKKSARVVGDVIGKYHPHGDTAVYDTIVRMAQPFSLRYMLVDGQGNFGSVDGDSAAAMRYTEIRMSKIAHSILADLDKETVDFVPNYDGTEHIPAVMPTRVPNLLVNGTSGIAVGMATNIPPHNLTEVINACLALIDNSELTFEEILEHIPGPDFPTAGIISGRAGIEEAYRTGRGKIKIRARASIDVTTGKETIIVHELPYQVNKARLIEKMAELVKDKRLEGISALRDESDKDGMRMVIEIKRGEVGEVVLNNLYKLTQMQVSFGLNMVALTNGQPKIFNIKEMLEAFVLHRREVVTRRTIFELRKARDRAHILEGLSIALANIDPIIEMIKNSNNRKESEEKLISQYYLTAEQAKAIVDLQLYKLSGMEHDKILSEYKALLDLIAELMHILATPARLMEVICEELVAIRDEFGDERRTEITL.................................................................................................................................................................................................................................................................................................................................................... 493
12 -90.9002xkj_E mol:protein length:767 TOPOISOMERASE IV  ali model follow..  38  255.ADITVEDKLTMTSLAHHATENRSVAEFTEQAYLNYAMYVIMDRALPHISDGLKPVQRRIVYAMSELGLKSSGKPKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLIEGQGNWGSPDDPSFAAMRYTEAKLSAYSELLLSELGQGTSEWQDNFDGSLKEPITLPARVPNILLNGTTGIAVGMATDIPPHNLREVVKGTIALIRNPQTSDEKLAEYIPAPDLPTAEIITPPEELLKIQTTGRGSYRMRAVYTIEK----NEIVITELPYQVSGSKVITQIADQMQAKKLPLVVDVRDESDHENTRLVIVLRSNIDAEAVMSHLFATTDLESSYRVNLNMIEDGRPQVKSIRRILLEWIEIRKKTVTRRLQYHLNRIEKRLHILAGLLIAYLDIDTVIRIIREEDQ---PKPVLMEHFNIDEIQAEAILELKLRHLAKLEEMEIRHEQDELSAKAAIIREQLENPESLKNLIISELKEDAKKFGDERRSPIVAREAVQIKEQDLMPAET.................................................................................................................................................................................................................................................................................................................................... 767
13 -89.8005eix_A mol:protein length:741 DNA topoisomerase 4 subunit B,DNA topoisomerase 4 subunit A  ali model follow..  40  233..QEKGDMADLEVEFMSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLGDGQGNWGAPDDPKFAAMRYTESRLSKYAELLLSELGQGTVDWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAKAAITLIEQPKTTLDELLDIVQGPDFPTAEIITSRAEIRKIYQNGRGSVRMRAVWSKED----GAVVITALPHQVSGAKVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVSNRVDMEQVMNHLFATTDLEKSYRINLNMILDGRPAVKNLLEILSEWLVFRRDTVRRRLNHRLEKVLKRLHILEGLLVAFLNIDEVIEIIRTEDE---PKPALMSRFGISETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQAILASERKMNNLLKKELQADADAFGDDRRSPLHE.................................................................................................................................................................................................................................................................................................................................................... 727
14 -69.2003qx3_A mol:protein length:803 DNA topoisomerase 2-beta  ali model follow..  16  269.DRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEM--SAYHHGEQALMMTIVNLAQNFSNNINLLQPIGQFGTRGGKDAASPRYIFTMLSTLARLLFPAVDDNLLKFLYD-DNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPH-------PMLPNYKNFKGTI--------QELGQNQYAVSGEIFVV---DRNTVEITELPVRTWTQVYKEQVLEPMTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYILNM--SLWSLTKEKVEELIKQRDAREVNDLKRKSPSDLWKEDLAAFVEELDKVESQEREDGAP..................................................................................................................................................................................................................................................................................................................... 786
15 -68.5001bgw_A mol:protein length:793 TOPOISOMERASE  ali model follow..  16  256................DPTLKEIPISDFINKELILFSLADNI-RSIPNVLDGFKPGQRKVLYGCFKKNLKSELKVAQLAPYVSECTA--YHHGEQSLAQTIIGLAQNFSNNIYLLLPNGAFGTTGGKDAAAARYIYTELNKLTRKIFHPADDPLYKYIQE-DEKTVEPEWYLPILPMILVNGAEGIGTGWSTYIPPFNPLEIIKNIRHLMNDEELE-------------QMHPWFRGWTGTIEEIEPLRYRMYGRI-----EQIGDNVLEITELPARTWTSTIKEYLLLGLSNDKIKPWIKDMEEQHDDNIKFIITLSPEEMAKTRKIGFYERFKLISPISLMNMVAFDPHKKYNSVNEILSEFYYVRLEYYQKRKDHMSERLQWEVEKYSFQVKFIKMIIEKELTVTNKPRNAIIQELENLGFPRFNKEGKPYYGSPNDEIAEQINDVKGATSDEEDEESSHEDTENVINGRIWSLTKERYQKLLKQKQEKETEL---ENLLKLSAKDIWNTDLKAFEVGYQEFLQRDRGGNVPNKGSKTKGKGKRKLVDDE.............................................................................................................................................................................................................................................................................................. 792
16 -67.2005gwk_A mol:protein length:806 DNA topoisomerase 2-alpha  ali model follow..  19  270.RRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNE-RSIPSMVDGLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEM--SSYHHGEMSLMMTIINLAQNFSNNLNLLQPIGQFGTRGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFL-YDDNQRVEPEWYIPIIPMVLINGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPL-------PMLPSYKNFKGTI--------EELAPNQYVISGEVAIL---NSTTIEISELPVRTWTQTYKEQVLEPMLNKTPPLITDYREYHTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVKKYDTVLDILRDFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRGYDSDPVKANYLLDMPLWYLTKEKKDELCRLRNEKEQELDTLKRKSPSDKEDLATFIEELEAVEAKEKQDGAPGFSS.................................................................................................................................................................................................................................................................................................................................................... 793
17 -53.6004gfh_A mol:protein length:1177 DNA topoisomerase 2  ali model follow..  17  664................DPTLKEIPISDFINKELILFSLADNI-RSIPNVLDGFKPGQRKVLYGCFKKNLKSELKVAQLAPYVSECTA--YHHGEQSLAQTIIGLAQNFSNNIYLLLPNGAFGTTGGKDAAAARYIYTELNKLTRKIFHPADDPLYKYIQE-DEKTVEPEWYLPILPMILVNGAEGIGTGWSTYIPPFNPLEIIKNIRHLMNDEEL-------------EQMHPWFRGWTGTIEEIEPLRYRMYGRIE-----QIGDNVLEITELPARTWTSTIKEYLLLLSGNDKIKPWIKDMEEQHDDNIKFIITLSPEEMAKTRKIGFYERFKLISPISLMNMVAFDPHKKYNSVNEILSEFYYVRLEYYQKRKDHMSERLQWEVEKYSFQVKFIKMIIEKELTVTNKPRNAIIQELENLGFPRFNKEGKPYYGSPNDEIAEQINDVKGATSDEEDEESSHEDTENVINGRIWSLTKERYQKLLKQKQETELENLLKLSAKDIWNTDLKAFEVGYQEFLQRDAEAR....................................................................................................................................................................................................................................................................................................................... 1177
18 -38.4001suu_A mol:protein length:312 DNA gyrase subunit A  ali model follow..  26  1..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MSDLMQKENIVVMLTKKGFLKRLSQNEYKLQGTGGKGLSSFDLNDGDEIVIALCVNTHDYLFMISNEGKLYLINAYEIKDSSRASKGQNISELINLGDQEEILTIKNSDLTDDAYLLLTTASGKIARFESTDFKAVKSRGVIVIKLNDKDFVTSAEIVFKDEKVICLSKKGSAFIFNSRDVRLTNRGTQGVCGMKLKEGDLFVKVLSVKENPYLLIVSENGYGKRLNMSKISELKRGATGYTSYKKSDKAGSVVDAIAVSEDDEILLVSKRSKALRTVAGKVSEQGKDARGIQVLFLDNDSLVSVSKFIK....................... 312
19 -38.3001zi0_A mol:protein length:307 DNA gyrase subunit A  ali model follow..  36  1...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAE...................... 307
20 -36.3003uc1_A mol:protein length:327 DNA gyrase subunit A  ali model follow..  31  1...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NAEDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDLRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGADQTGN.... 327
21 -35.3003l6v_A mol:protein length:370 DNA gyrase subunit A  ali model follow..  35  2............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DLIAPEDVVVTLSHAGYAKRQPVSAYRAQRRGGRGRSAASTKEEDFIDQLWLVNTHDTLLTFTSSGKVFWLPVHQLPEAGSNARGRPIINWIPLESGERVQAVLPREYADNRYVFMATRNGTVKKTPLSEFAFRLARGKIAINLDEGDALVGVALTDGDRDVLLFASNGKTVRFGESTVRSMGRTATGVRGIRLAKGEEVVSLIVSGDVAYILTATENGYGKRTPLAEYPRKGRGTQGVIGIQTTERNGKLVRAVLLGSTDEVMLISDGGTLVRTRGSEISRVGRNTQGVTLIRLSKGEKLQAVERLDASLEEPEDVVDEAVAITSDAPPA 368
22 -33.1001wp5_A mol:protein length:323 topoisomerase IV  ali model follow..  23  1.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MVASEDVIVTVTKDGYVKRTSLRSYAASNGQDFAM-----KDTDRLLAMLEMNTKDVLLLFTNKGNYLYCPVHELPDIRWKDLGQHIANIIPIDRDEEIIKAIPINDFELNYFLFVTRNGMVKKTELKHYKAQRYKPLTGINLKNDDQVVDVHLTDGMNELFLVTHNGYALWFDESEVSIVGVRAAGVKGMNLKEGDYIVSGQITSKDESIVVATQRGAVKKMKLTEFEKATRAKRGVVILRELANPHRISGFVVAQDSDTIYLQTEKSFIETIKVGDIRFSDRYSNGSFVLDEEENGRVISVWKVEAEDKTEKLAAALE.......... 319
23 -28.8003no0_A mol:protein length:276 DNA gyrase subunit A  ali model follow..  20  2..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SITVAVLQDGSIIPV----------------EELPLEKAPVVNILRVPFTEGLFLVSNRGRVYWIAGSQALQGSKVSLKSREEKIVGAFIREK----------FGNRLLLATKKGYVKKIPLAEFEYKAQ-GMPIIKLTEGDEVVSIASSVDETHILLFTKKGRVARFSVREVPPSTPGARGVQGIKLEKNDETSGLRIWNGEPYLLVITAKGRVKKISHEEIPKTNRGVKGTEVS---GTKDTLVDLIPIKEEVELLITTKNGKAFYDKINDIPLSTKKSIPRTRWKLEDDEIIKVVIKKSE...................... 276
24 -22.7004mn4_A mol:protein length:259 DNA topoisomerase 4 subunit A  ali model follow..  13  1......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SNASEPVTIVLSQMGWVRSA------KGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQGEPLTKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRA--GKALITLPENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSK-GKGNKIINIPSAEAARGEDGLAQ...................... 195
25 -21.5004ely_A mol:protein length:156 DNA gyrase subunit A  ali model follow..  33  2......................................................................................................................................................................................................................................................................................................................................................................GSSSSGLVPRGSHMTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVALYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADR.............................................................................................................................................................................................................................................................................................................................................................................. 150
26 -21.5004elz_A mol:protein length:153 DNA gyrase subunit A  ali model follow..  36  2......................................................................................................................................................................................................................................................................................................................................................................GSSSSGLVPRGSHMTRRTIFELRKARDRAHILEGLALALANIDEIIELIKNAPTPAEAKEGLISRYFLTEQQAQAILELRLHRLTGLEHEKILDEYKALLDEIAELMHILAS................................................................................................................................................................................................................................................................................................................................................................................. 147
27 -9.2503h0g_A mol:protein length:1752 DNA-directed RNA polymerase II subunit rpb1  ali model follow..  192...SWKRGKDESDLPEKRLLSPLEVHTIFTHISSEDLAHLMIITVLP-----VPPPSVRPSISVDGTSRGEDDLTHKLSDIINANVRRCEQEGAHIVSEYEQLLQFHVAT---YMDNEAGQPQALQKSGRPLKSIRARLKGKEGRLRGNLMGKRVDFSAR-------TVITGD--PNLSLD-ELGVPRSIAKTL-PETVTPY-------------NIYQLQELVNGPDHPGAKYIIRDTGERIDLRYHKRAGDIPGWRVERHIRDGDVVIFNRQP-SLHKMSMMGHRIRVMPYSTFR-------NADFDGDEMNMHVPQSEETRAEIQEITMVPK-------QIVSPQSNKPVMGIVQDTL-RKFSLRDNFLTRNAVMNIMLWVPDWDGIQILSLIIPKGINLIRDDDKQSLSNPTDSGMLIE-KTVGASQGGLVHTIWKEKGPEICKGFFNGIQRVVNYWLLHNGFSIGIGDTIADTMKEVTRTVKEARRQVAECIQDAQHNRLKPEPGMTLRES---------FEAKVSRILNQARDNAGRSAEHSLKDSNNVKQMVAAGSKGSFINISQMSACVGQQIVEGKRIPFGFKYRTLPHFPKDDDSPESRGFIENSYLRGDTAVKTAETGYIQRRLVKAMEDVRNAMGDIIQFAYGEDGLDATLVEYQVFDSL....................................................................................................................................................................... 892

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.