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Query: gi|13507742|ref|NP_109691.1| DNA gyrase subunit B MPN003 [Mycoplasma pneumoniae M129], from M.pneumoniae

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MEDNNKTQAYDSSSIKILEGLEAVRKRPGMYIGSTGEEGLHHMIWEIIDNSIDEAMGGFASTVKLTLKDNFVTIVEDDGRGIPVDIHPKTNRSTVETVFTVLHAGGKFDNDSYKVSGGLHGVGASVVNALSSSFKVWVAREHQQYFLAFHNGGEVIGDLVNEGKCDKEHGTKVEFVPDFTVMEKSDYKQTVIASRLQQLAFLNKGIQIDFVDERRQNPQSFSWKYDGGLVQYIHHLNNEKEPLFEDIIFGEKTDTVKSVSRDESYTIKVEVAFQYNKTYNQSIFSFCNNINTTEGGTHVEGFRNALVKIINRFAVENKFLKETDEKITRDDICEGLTAIISIKHPNPQYEGQTKKKLGNTEVRPLVNSIVSEIFERFMLENPQEANAIIRKTLLAQEARRRSQEARELTRRKSPFDSGSLPGKLADCTTRDPSISELYIVEGDSAGGTAKTGRDRYFQAILPLRGKILNVEKSHFEQIFNNVEISALVMAVGCGIKPDFELEKLRYNKIIIMTDADVDGAHIRTLLLTFFFRFMYPLVEQGNIYIAQPPLYKVSYSNKDLYMQTDVQLEEWKQQHPNLKYNLQRYKGLGEMDAIQLWETTMDPKVRTLLKVTVEDASIADKAFSLLMGDEVPPRREFIEQNARNVKNIDILast
1 -57.900PF00204.25; A9KS52_LACP7/226-396; DNA gyrase B  ali follow..  40  1...................................................................................................................................................................................................................................GIKSFVSYINREASVIHEEPIYIE----------GKSGDIEVEVALQYTNSFSEQINAYCNRINVVDGGTLVTGFKTALTRVMNQYARELGVLKEKDENFDGKDIRNGLVTIISIKHPDPQFEGQTKTKLGNTDAKSAVEDVFSGEVTRFFDKNVEILKAILENSMRSYTARKASDKARSA.................................................................................................................................................................................................................................................. 171
2 -31.600PF00986.21; M9X0E0_MANHA/738-800; DNA gyrase B subunit, carboxyl terminus  ali follow..  63  1................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RKGLTIQRYKGLGEMNPEQLWETTMDPVARKMLQVNITDAIAADKLFSTLMGDEVEPRRDFIE........... 63
3 -30.300PF16898.5; K5XBZ3_PHACS/641-767; C-terminal associated domain of TOPRIM  ali follow..  17  1.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................FVTPIVRVTKGNQKINFFTIPEYEQWLENTPDHKWKSKYYKGLGTSKDEDAREYFSRMNKH-MIPFATVKDGERDLIDLAFSKKKADDRKEWLRNLEPGT..... 100
4 -13.900PF13589.6; A5G4D8_GEOUR/22-165; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase  ali follow..  21  2......................................EPHSALMDIIDNSVAAD----ALNVKLYVDLVEGYRVVDDGKGM-----------DEDGIKNAFKLGSDANYKQNSL--SKYGMGLKSAGFLGLRIQIISKTEGQ........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 101
5 -8.810PF02518.26; O52937_9CYAN/626-739; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase  ali follow..  21  2...................................DSTRLQQVVWNLLSNAVKFTKNGGRVEIRLEVDSQAEIKVSDTGKGISPDFLPH--------VFESFR---QADATITRKFGGL-GLGLAIVRHLVE--TIYAESPGEDLGATFT.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 107
6 -6.530PF13581.6; A9B3A3_HERA2/9-137; Histidine kinase-like ATPase domain  ali follow..  16  24...............................LNEHTAWEIELAVDEAATNIIQHAYSAERPDVRLVCGRDGVVRLFDRGVPFPETVPPPDLTSSIE-------------------TREAGGLGMYLMGRMMDDVQFNYNPETGENELHMSK................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 129
7 -6.250PF13362.6; Q8Y0S6_RALSO/228-334; Toprim domain  ali follow..  20  1...................................................................................................................................................................................................................................................................................................................................................................................................................................................TVYIVESPNALSVECCHL----------------------------PEGTAAFALRGTANVDKIDWTFLRGKRVVIALDHTDPVN.................................................................................................................................. 58
8 -6.080PF11536.8; Q5JEB1_THEKO/3-242; Protein of unknown function (DUF3226 topsan)  ali follow..  11  2...................................................................................................................................................................................................................................................................................................................................................................................................................................................RLLLLEGRTDVSFFLPLIKELYG--LPVLEEGPKKKGLSRAICLSKDDTRLVVWHANGKDNLKNALKLITPAIIGIARDVDTEESILNWAKSTLQSGGFEPDVKDGYLMINGIKVIPFGIGEDARDIDLKKELELLMALLAKKESSLSKLEGISQLRKDLGRKLTPKDIMHLLAIARNYGGDSMSGLYRNFIEKLIRENRELVEEFLNESGLKE. 234
9 -5.730PF01751.22; RGYR_PYRHO/641-803; Toprim domain  ali follow..  12  4.........................................................................................................................................................................................................................................................................................................................................................................................IVESPNKARTIASFFGQPSKRKIGDLTAYEVSIGDKMLTILASGGHMFD------------LVTNEGYHGVLILKNNGKP-YFVPVYDTIKRCRDCGHQFVDWEQKGVCPRCGSRNVHDALENVKAMR-DEILIGTDPDTEGEKIAWDIRNVLAPYAPNIKR............................................................................................................... 157
10 -5.620PF09929.9; Q162U3_ROSDO/97-212; Putative PD-(D/E)XK phosphodiesterase (DUF2161 topsan)  ali follow..  17  2.............TVRLSDGLVEVHCDPGPYRPRKSKKRQSALLREFARRAGDPNEGGQTRAGLITAYRQDATKIFEVGASKGAEVARETGVVNATRIMRDDHYN-------EKVATGVYGLTSA............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 112
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. Discovering new genes with advanced homology detection. Trends Biotechnol. 2002 Aug;20(8):315-6.