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Query: gi|13507743|ref|NP_109692.1| DNA gyrase subunit A MPN004 [Mycoplasma pneumoniae M129], from M.pneumoniae

Results of PSI-BLAST search in nr85s
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# E-value Template Links and tools%idFirst MAKQQDQIDKIRQELAQSAIKNISLSSELERSFMEYAMSVIVARALPDARDGLKPVHRRVLYGAYTGGMHHDRPFKKSARIVGDVMSKFHPHGDMAIYDTMSRMAQDFSLRYLLIDGHGNFGSIDGDRPAAQRYTEARLSKLAGELLRDIDKDTVDFVANYDGEEQEPTVLPAAFPNLLANGSSGIAVGMSTSIPSHNLSELIQGLILLIDNPDCTINDLLGVIKGPDFPTGANIIYTKGIESYFETGKGNVVIRSKVSIEQLPTRAALVVTEIPYMVNKTSLIEKIVELVKAEEITGIADIRDESSREGIRLVIEVKRDTVPEVLLNQLFKSTRLQVRFPVNMLALVKGAPKLLNMKQALTVYLEHQLDVLIRKTQFNLKKYQERFHILSGLLIAALNIDEVIAIIKKSANNQVAMEALHERFGLDEIQARAVLDMRLRSLSVLEVNKLQTEQQELKALIEFCQQVLADKQLQLKLIKEQLTKINEQFGDPRRSEILYGISEDIDDEDLITQENVVITMSTNGYLKRIGVDAYNLQHRGGVGVKGLTTYTDDSISQLLVCSTHSDLLFFTDKGKVYRIRAHQIPPGFRTNKGIPAVNLIKIDKDEKICALISVNDYQNGYFFFCTKNGTIKRTSLSEFANILSIGKRAILFKENDVLFSVIRTSGQDDIFIGSTAGFVVRFHEDTVRPLSRAAMGVLGINLNQCEFVNGLSTSSNGSLLLSVGQNGIGKLTSIDKYRLTKRNAKGVKTLRVTAKTGPVVTTTTVFGNEDLLMISSAGKIVRISLEQLSEQRKNTSGVKLIKLKEKERLETVTIFKKEEAIKTTTATETDDVGSKQITQLast
1 0.000e+00UniRef50_A0A2K3IXI8 DNA gyrase subunit A (Fragment) n=3 Tax=cellular organisms TaxID=131567 RepID=A0A2K3IXI8_9EURY  ali  52  12......................RAIETEMKRAFIDYSMSVIMSRALPDVRDGLKPVHRRILYAMNDMGMVSEKPFKKSARVVGETLGKYHPHGDQAVYDSLVRMAQDFSLRYPLIEGQGNFGSIDGDSAAAMRYTESRMAKITKYILKDIEKDTIQWVDNFDGSLKEPVMLPSVLPNLLINGVSGIAVGMATNMPPHNLSEIVDGIIATIDNPDISINELIDIIKGPDFPTKGIIYGKTGIFNAFSTGRGLLKVRARTNIEGIDKKKIII-TELPYQVNKSKLLKNIADLVKNKKIEGISDLRDESDRKGMRIVIYLKKDAIEDVVLNLLYGHTDLQTTFGVLNLAIVKGEPKILNLKELICNYIEYRLEIITSRTNFDLNKAKEKIHILEGFIIALNNIDEVIKIIRGSKTVDDAKNNL................................................................................................................................................................................................................................................................................................................................................................................................................................... 408
2 0.000e+00UniRef50_A0A2V8S811 DNA gyrase subunit A n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8S811_9BACT  ali  37  1.............................................................................................................................................................................................................................................................MRARATVEERKGKDRIVVTQIPYQVNKTRLIEQIAGLVNDKKIDGVTDIRDESDRDGIRVVLDLRRDAVPKVILNNLYKHTQMQETFGAIFLAIVNNRPQVLNLKQMIGHFIDHRREVVVRRTAFELARAEERAHILEGLKIALDNLDEMVALIRAAKSPDEARQAMRLRFKLSDAQAHAILDMKLQRLTGLERQKILDEYTETLKQIARLKEILSNDRLVYGVMVEELREIRKNYADARRTEII-GQQGDISVEDMIAEEEMVITVSHAGYVKRNPLTLYRSQRRGGKGKIGMTTREEDFVEHLFVASTHASILIFTTRGRVHWLKVHEIPQIGAAGKGKNIVNFVELTPEEKIAALVATKEFRDDQYVFCTKSGIIKKTPLSAYGNPRAGGIIATGIDEGDELLSVKLTDGKQEIFMATAQGQSIRFPEEEVRPMGRGARGVIGMRREERDVVVEMDSLRKGGKILTVTEKGYAKRTEVEEYRLQGRGGSGIINCKITDKNGPVVQAMHVDDDHQVMVITAFGKIIRTDVRSISLMGRPTQGVRLIHLEEGDRVVAVERVAEKDIDN................. 587
3 0.000e+00UniRef50_A0A166IJM0 DNA topoisomerase (ATP-hydrolyzing) n=7 Tax=Bacteria TaxID=2 RepID=A0A166IJM0_9MICO  ali  52  1MADEADTPTGPDDSEDHDKIEPVDLQLEMQRSYLDYAMSVIVGRALPEVRDGLKPVHRRVIYAMYDGGYRPDKAFSKCSRVVGDVMGQFHPHGDSAIYDALVRLVQPWSLRYPLALGQGNFGSPGNDGAAAPRYTETKMAPLALEMVRDIDKNTVDFQDNYDGRTREPAILPARFPNLLVNGSVGIAVGMATNIPPHNLREVAAGAKWALENPEATREELLERIKGPDFPTGAQILGVRGIQVAYRTGRGSITMRAVVSIEEIQGRTCLVVTELPYQVNPDNLAVKIAELVKDGRVSGIADIRDESGRTGQRLVIVLKRDAVAKVVLNNLYKHTPLQENFGANMLAIVDGIPRTLSLDGFIRAWVDHQVEVVVRRTQYLLDEAEARIHILRGYLKALDALDE..................................................................................................................................................................................................................................................................................................................................................................................................................................................... 418
4 0.000e+00UniRef50_A0A2N1PF42 DNA gyrase subunit A (Fragment) n=7 Tax=Terrabacteria group TaxID=1783272 RepID=A0A2N1PF42_9BACT  ali  46  1MSKKT--IDQKIDAFIEEKITSERLEDIIGERFGRYSKYIIQDRALPDARDGLKPVQRRILYAMYKMGMFNDKPFKKSARIAGEVMGKYHPHGDSSIYEAMVRMSQNFKMGVTLIDMHGNNGSIDGDSAAAMRYTEARLSKEAEYLIADIDKRTVPFIPNFDDEELEPTVLPAKFPNLLVNGANGISAGYATKIPPHNLKEIIKATIERIDKPDMTIDRLLKIVTGPDFPTGGIVQGKEGIRQAFETGSGKVIVRSRTFFETNKDQTRIVVTEIPFEVNKSELVKSIDMLRIDKKLEDLQEVRDESDREGMRISIELKKEANPDICLAYLFKNTDLQVNYNYNMVAIHHQRPVQMGVIEILDAYINHQKEVITNRSNYDLDKAERRSHIVSGLIKMVDVIDEVVHIIRHSKNKQNSKDNIIKQFGFTELQAEAIVMLQLYRLSSTDIDALIKESNELDERIIWLKKVLSDEQMLLSVIKKEL..................................................................................................................................................................................................................................................................................................................................................................... 481
5 0.000e+00UniRef50_UPI00084A2E8F DNA topoisomerase 4 subunit B,ParE30-ParC55 fused topo IV from S. pneumoniae n=1 Tax=Streptococcus pneumoniae TaxID=1313 RepID  ali  44  248.................SNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMHGNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFPNLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVVVRSKTEIEKKGGKEQIVITEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDNFTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALIRASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAIIGDERTMYNLMKKELREVKKKFATPRLSSLED.................................................................................................................................................................................................................................................................................................................................................... 730
6 0.000e+00UniRef50_A0A090VD18 DNA topoisomerase (ATP-hydrolyzing) n=3 Tax=Bacteroidetes TaxID=976 RepID=A0A090VD18_9FLAO  ali  40  1.............................................................................................................................................................................................................................................................MRAKTNIEEVNGRECIIVDEIPYQVNKADMIKKTADLVNDKKLEGISLIRDESDRNGMRIVYVLKRDAIPNIVLNKLFKYTALQSSFSVNNIALVNGRPQLLNLKELIHYFVEHRHEVVVRRTTYELRKAEERAHILEGLIIASDNIDEVIKIIRASNNADEARNNLIERFKLSEIQAKAIVEMRLRQLTGLEQDKLRAEYDDIMKTIIDLKDILDRKERRMDIIKEELVVVRDKYGDERRSVI-EYAGGDLSIEDMIPNESVVITISHAGYIKRTSLTEYKTQHRGGVGQKASTTRNEDFLEHLFVGTNHQYMLFFTQKGKCFWMRVYEIPEGSKTSKGRAIQNLVNIEQDDKVMAFICTQDLKDHYVIMATKKGQVKKTSLEQYSRPRTNGINAITIKDDDVLLEAKLTTGESQVMLALKSGKAIRFEEAKTRPMGRGASGVRGIRDEETDEVIGMIAVDDESNVLVVSENGYGKRSSLEDYRITNRGGKGVKTISITEKTGNLVSIKNVTDDDDLMIINKSGVAIRLAVADLRVMGRATQGVKLINLKGKDSIAAVAKVMHEDEEIVLEGEEGETSVEG.... 590
7 0.000e+00UniRef50_A0A2E8JRU6 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Candidatus Saccharibacteria bacterium TaxID=2026720 RepID=A0A2E8JRU6_9BACT  ali  31  30.AGQSVPPIDGDGPREPINFDDDSLESYATKAYLSYGIAVLKGRALPDVSDGQKPVQRRILYAMHDLGLTSSSKHVKSARVVGEVLGKFHPHGDTSVYDAMVRQAQDFSLRYPLIDGQGNFGSRDGDSAAAMRYTESRLTKYSELLLSEIDLNTVDFKDNYDGAFREPAVLPARLPMLLLNGASGVAVGMATECPSHNLSEISSLAADLIKNPGLTDDSFYEQFIGPDFPGGGLITPRDQILAAYREGRGSLALRCSYEFEELRGQWKLVVKELPHGVSAAKVLEQIEALSNPQFLNLIDTVRDESGKDAVRLVFEPKSSIDREEFAKTLLAYTSLESTVSINLVSIGDGRPAQKSLRTMLDEWCSFRLQTVTNRINNRISQIEKRLHILEGRKIAFLNIDRVIAIIRASDNP---KEDLMHAFGLSDTQADDILEIRLRQLARLEGFKLDQEIKALKEELESLRDILSSDSSLRDFVSREVLSDGSKYADERRTKMYESERVTLSEAATV-NEKITLLLSKKGWI--------KQRGGHGVDLSAVTFKEGDSLLQAIETESANPINLLASDGRAYSLSVTQIPSG----KTDGVPLSSMCDFEQKVKPIALVAGAEKDEFFVCCDAGYGFISNVGALSTRNKAGKAFFTLKDGESLYRPLKLKEYFCCINDTS-GKGLAFQVTELRF-ADKGRGLQITPLKPGEKIIQPQFVSDLNKVVFIVAKGE-TRTEYNQFELGARGQKGRVVPVSVKKFD.................................................................................. 790
8 0.000e+00UniRef50_C2KY16 DNA topoisomerase (ATP-hydrolyzing) n=15 Tax=Bacteria TaxID=2 RepID=C2KY16_9FIRM  ali  49  2............EPNIFDKVQDVDLKKTMENAYIDYAMSVIVSRAIPDVRDGLKPVQRRVLYALQSLGVTPDKKTKKCATIVGETMGKYHPHGDSSIYGSLVYMGQPWSMRHVLIDKQGNFGSEDGDSPAAMRYTEAKMSRLAGEMLAGINKNTVDFMPNFSNEYEEPVVLPSRFPNLLVNGATGIAVGMSTNIPPHNLREVIKGVDCIIDNRKTEIEELLPIIQGPDFPTGATILGKRGIEEAYRTGRGKIKMRAICEIEPMNGKNRILVKELPYLVYRSRVIEKIAELVKDKRIDGITYIHDAAGKNKAKIAIECRKDVNPHVILNQLYKHTQLQETFGVIMLCIVRGEPKILNLLEILEEFLAHQIQVVTRRTQYDLQKCEDRAHILEGLLKALDHIDEIVAIIRAAKNVEEAKQNLITRFAFTEVQAQAIVDMRLR............................................................................................................................................................................................................................................................................................................................................................................................................... 435
9 0.000e+00UniRef50_R4RSX1 DNA topoisomerase (ATP-hydrolyzing) n=5 Tax=Bacilli TaxID=91061 RepID=R4RSX1_LACFE  ali  44  1..............MADTRIEELTLEQIMGDRFGRYSKSIIQERALPDIRDGLKPVQRRILFAMNKDGNTYDKGFRKSAKSVGNVMGNFHPHGDSSIYEALVRLSQDWKLREPLIEMHGNNGSMDGDPAAAMRYTEARLSKIAGRMLEDIDKDTVEMTLNFDDTEKEPVVLPARIPNLFVNGATGISAGYATEIPTHNLGELIDALIYLLAHPAASLDDLMKFVPGPDFPTGAIIQGKDGIKKAYETGRGRVVVRAKTSIETLGGREQIVVTEIPYEVNKAQLMKRITDLRLNKKVEGIADARDETDRTGLRIAIELKRGVDAQGVLNYLLKNTDLQINYNFNMVAIDDQRPVRVGLKHYLASYLAFQKEVITRRTRFDLRRAQSRLHIVEGLIKALSILDQVIATIRASKNRKDAQQNLVAAYDFTPTQAEAIVALQLYRLTNTDVHRLRTRASQVNRANRKLQADPDGRK............................................................................................................................................................................................................................................................................................................................................................................... 459
10 0.000e+00UniRef50_C7LJX9 DNA topoisomerase (ATP-hydrolyzing) n=15 Tax=Bacteroidetes TaxID=976 RepID=C7LJX9_SULMS  ali  46  2.................EKIISINLEEEIKASYIDYSMSVIVSRALPDGKDGLKPVQRRVLYGMYEQGAF--KNYRKSARIVGDVLGKYHPHGDSSVYEAIVRMAQSWSLRYPLIDGQGNFGSIDNDPPAAMRYTEIKLQKVSEEMLFDLKKDTVDIKLNFDSSCKEPIVLPTVIPNLLINGSSGIAVGIATNMPPHNIVESINAICSYIENTDISIEELMKDIIAPDFPTGGIIYGYEGVKKAFLTGRGKILLRSKVFFEKIGGCYCLIIKEIPYQIRKEDLIKKTLKLIKEEKLEGISKIRDESDRTGMRIVFYLKKNVNKHLLLKNIFKYTPLETTFSVNNIALVNGKPVQLNLKDIIKHFVNHRHEVLIRRSKFDLKNAKEKAHIIKGFYLVLDNIETVIELIKSSKEKNHAKKKLLIKFNLSEKQVKAILNLKLNSLTKLENEKIKKDYLKLKKDISYYTNIKTDIFFQKKIIKKELKQIKEKYGDLRRTQI...................................................................................................................................................................................................................................................................................................................................................... 479
11 0.000e+00UniRef50_UPI000DACD3FB DNA topoisomerase n=1 Tax=Bradymonas sediminis TaxID=1548548 RepID=UPI000DACD3FB  ali  35  1.....................................MSVITSRALPDVRDGLKPVQRRILYGMFNLRLTHDAKHMKSARIVGEVMGKYHPHGDQSIYDAMVRMAQDFSLRYPLVSGYGNFGSVDGDSAAAMRYTEARLTNLSSELLDEIKKNTVLFRPNYDGTDSEPTVLPSQVPTLLINGATGIAVGMATNIPPHNLGECLDALIALIDEPTLEIEDLVRHIKGPDFPTGGVMLNSDELLEMYKTGSGPILMRASWEVESHDYKKFIVITSLPYTVNKSTLVEKIADHIIQGNLPQVQDVRDESTDD-IRVVLELKRGTDPELAMAYLLKHTPLESRFHVNMTCLVPAEQPRFSLKELLDYLREFQAEVLVRRLLFELEKILGRIHILEAFEIIFNDLDKAIELIRASTSKKDAAKRLIEYFKIDALQADAILETKLYRLAKLEIENIRAELAERRKEAKKIRTLLMSETKRWEHIRNEFVVLRDVYGDARRTVIENAPELEYSEADYILDEDVWVIVTRDGW--------FKRQK-SYSDLSTIRVRDNDKLGWVMPGRTRNTLLIFTTTGRVYTMRIDDVPSTTGYGDP--IQAHFDFEDGEKIAGVITMDKRVLKPMIAISAQGQGVRFSLEGYDEPTVKGRMYMRLGKKDSVINVEPCTCVEEVTIATREGRGLTFQSREINVYKGAAKGVKTISLEKGDEILAWTLSTGYYEGLEV-ETSRGKKLTISAFQPTSRGNKGRWVIQ........................................................................................ 788
12 0.000e+00UniRef50_B9SK06 DNA gyrase subunit A, chloroplast/mitochondrial, putative n=8 Tax=Pentapetalae TaxID=1437201 RepID=B9SK06_RICCO  ali  50  99.........KDSNGGRDARVVHTELHKEATEAYMAYAMSVLLGRALPDVRDGLKPVHRRILFAMHELGLSSRKPFKKCARVVGEVLGKFHPHGDSAVYDALVRMAQDFSLRSPLIQGHGNFGSIDADPPAAMRYTECRLEALTEALLADLELDTVDFVPNFDDSQKEPSLLPARLPTLLLNGSSGIAVGMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPGPDFPTGGLIMGNLGILEAYRTGRGRIIVRGKTEVESKTKRTAVIIKEIPYQTNKASLVEKIAELVENKNLDGVSDIRDESDRSGMRIVIEVKRGSDPSIVLNNLYRLTPLQSSFSCNMVGILDGQPKQMGLKDLLQAS-YFRCSVVERRARFKLLQAQERRHIVEGIVIGLDNLDGVIRIIKE.............................................................................................................................................................................................................................................................................................................................................................................................................................................. 501
13 0.000e+00UniRef50_A0A249LG14 DNA topoisomerase (ATP-hydrolyzing) n=4 Tax=root TaxID=1 RepID=A0A249LG14_9ACTN  ali  44  1MATKTKKPAGPKPGEFPGKIVDIDVSSEMSESFLEYAYSVIYSRALPDARDGLKPVHRRILHQMAEMGLRPDKGHVKSARVVGEVMGKLHPHGDGAIYDALVRMAQSFSMRLPLIDGHGNFGSLDA-GPAAMRYTEARLAQAALTMVAETDEDTVDFGANYDGQIFEPQVLPAAYPNLLVNGGSGIAVGMATNMAPHNLGEVIAATKHLIENPTATVKALMKFIPGPDFPTGGELVGLEGVREAYSTGKGSFKVRATVEISKVTRKMGITIKELPFTIGPEKVVERIADLAKAKKIQGISDIIDLTDQTGTNVVIELKNGFEPEAVLEQLFKLTPMEDAFAINAVALVKGRPQTLGLKELLQVFIDHRIEVVRRRSEFRKAKASGRLTLVDGLLKAIIDIDKVIKIIRASDDASIAKDALIKGFKLNDEQVTYILDMPLRRLTKMSKIELETEQKELKSTIAALNTLLKSEDAIKKQVSTELDAVAKAFATPRRTRI...................................................................................................................................................................................................................................................................................................................................................... 502
14 0.000e+00UniRef50_A0A2G6I190 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Spirochaetales bacterium TaxID=2026792 RepID=A0A2G6I190_9SPIR  ali  36  2...............................................................................................................................................................................................................................................GYKLAAHTGRGKVVIRSRYYLEEVSDKEAIIITELPYQVNKASLIIRIAELVRDKKIDGISDLRDESDRDGMRVVVELKRGASPKVVLNHLFTHTQLQVNFSVNNLALVDGRPKLLNLKDLISEFVRHRQNVVRRRSEFELKRAREREHILIGLKIALENIDEVVEIIKKSKTVALARTNLMTRFDLSEKQAQAILDLRLQKLTSLETQKILDELEEIRVTIAYLEDLLAHEEKILGVIKEETLELSQKFGKPRATEINPEEVIQVNIEDLIAEEDMVVVISNRGFIKRISASLYKQQGRGGKGARTSDLKEDDFIEHVFLASTHSYILFVTSEGKAYWIKVFEIPEGSRTSRGKHLRTIFEFAPEEDITAMVPLQEFDETSLFMATRQGVVKRVATYDFRNARTRGIIALNLDEGDRLVSATLVNGDEDVFLVTRNGKGLRFPETSVRRMGRNSRGVRGIRLADNDELIGVCPVREEEKMLLVSEKGYGKRTDYDEFSPHGRGTGGQRAYGVNQRTGALVAALPVHSDDSCIGITSQGKALRFAVDQVSQMGRSAFGVRILNMNGNDSVIGIARQPKEDESDADTGNGEETASEGE... 600
15 0.000e+00UniRef50_I4FSX0 DNA topoisomerase (ATP-hydrolyzing) n=5 Tax=Bacteria TaxID=2 RepID=I4FSX0_MICAE  ali  49  1MAKQ-------LDFLASGQIIPTALHQEMERSYLEYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDRPFRKCARVVGDVLGKYHPHGDQSVYEALVRMVQDFSSRYPLLSGHGNFGSIDNDPPAAMRYTETRLAGIGQAVLGGISEAIVNFSSNFDNSQQEPVVLPAQLPILILNGCSGIAVGMATNIPPHNLGEVVEGLIALIDNPDLSEEKLVEIIPGPDFPTGGEILDDTGIREAYRTGRGIIPVRGVAKTETIRERTAIVVTELPFQVNKAAWIEKIAELVNLGKLEGIADIRDESNREGIRVVIELKRESQPQQVLAALYQQTALQTNFGAIILALVDNQPRQLSLKQVLQEFLRFRETTLTRQYGDELQQASDRLHLVEGLLLALQNIDRVVDILKNAPDGTTAKYRFQAELGISDAQADSILAMPLRRLTGLE......................................................................................................................................................................................................................................................................................................................................................................................................... 447
16 0.000e+00UniRef50_UPI000C0884AE DNA topoisomerase IV subunit A n=1 Tax=Candidatus Fonsibacter ubiquis TaxID=1925548 RepID=UPI000C0884AE  ali  34  2..............KNKDNILNASLATEFSQKYLAYALSTITHRALPDVRDGLKPVHRRLLYAMYLLNLGSKLQPKKSARVVGDVIGKFHPHGDQSVYDALVRLAQDFSIRYPLVNGQGNFGNIDGDNAAAMRYTEAKLTEISELLLENIDEETVDFKSTYDGDLQEPLVFPAKFPNLLANGASGIAVGMATSIPPHNIVEICEGLKIVNHDKNVSIKELLKVLPGPDFPTGGILNNKSEILKAYTSGRGFFELRSSYKIEDLGGQYQISIHEIPYQVSKSTLIEKIADLIISKKNKLIDNVIDESDQLVRIIIRPKNRNVKPEVLMESLFRQTDLQVRIPLNMNVLNSKQPKVMSIKEVLVNFLSHRYEVLIRKSEFRLKNIKNRIEILIGFIKVYHNLDKIIKIIRNADDP---KLQLVKKFKFTQNQVNAILDMRLRNLRKLEEKEIKQEYKDLLSEKNFLTKLLSSKSLQKKEIDSEIDFLIKKFKDN---PLLGKRRTQLDKFGSVNEEDFDNEIKSDHPLTITILKNGFIKSQKSFVKNLEEQIGNESSSLLIHARSNDKVILASNFGKFYTIEADNILTGSSTGRP--ISSYLSLTDNEKI--IDGFKFDNEGEIFIYTREGYGFVALEKNLETNKKTGKKVMNVKGDDRVIGVSRVIKDYDICEADKKNKMLAFNINELPKLD-KGRGVILVK-GKSLKVINATVFNSKSVIKDQMDKTLFDKSAIED-NFAKRAQSGKII.......................................................................................... 730
17 0.000e+00UniRef50_A0A2W4U583 DNA gyrase subunit A (Fragment) n=1 Tax=bacterium TaxID=1869227 RepID=A0A2W4U583_9BACT  ali  36  1................................................................................................................................................................FDDRLQEPTVLPAKLPNLLVNGSSGIAVGMATNIPPHNLREVAAAIKHLVAHPDCSVDELMRHIKGPDFPTGGFIVGLDGIKEAYRTGRGRIIMRARIQRESLRGKEQLVVTELPYGISKARVVEQIAQLVRERKLEDIADLRDESDREGMRVVIELRRGAQVPRVLTTLFKNTALQATFGAILLALDNGVPREMNLKEILERYRDHRLEVIQRRARFELERAQAEAHITEGLLVALDNIDAVIRIIRRAQDREVAAAQLRKRFRLSEAQAGAILDMRLARLTALEXXXXXXXXXXXXXXXXXXXXXXXXXXXXLALLVAELDELVERYGDARRTRIVK-GTAELPVEDLIAQENVVVTLTHEGYINRVPLDLYRRRVRRGTSVLRTK-KGGDFLERAFIAGTRDTLLVFTQDGLAHALPVHKVPEASTGRGTPLVRALGLGKRAAVAAMIPVADFSADRHLVFLTAGGVVKRTTLDQFAGIRAGGITAMGIRKGDRLLDVQLSDGTNDVVIVTRQGRAIRFPEAEIPAVGRAAQGVRGINLREGDRAIGMVVVRRDASLCTITENGYAKRTPIGEYAVQRRGGVGAAALAVDKRTGPLVAVEELLPGDELMVLTAKGAGVRVAADDLPEQRRTSKGKRVLEPEPGDRVVEVARIVAQEEGGEAKGARK.......... 668
18 0.000e+00UniRef50_Q4A6Z3 DNA topoisomerase (ATP-hydrolyzing) n=4 Tax=Mycoplasma synoviae TaxID=2109 RepID=Q4A6Z3_MYCS5  ali  30  1..........MSKKEIIEKIITKSVDKIMEERFETYSKYVISNRAIPDVRDGLKPVHRRILYSMYALGLDFDKKFKKSARIVGDVIGKYHPHGDTSVYNAMINLAQWWKMNIPLLSMHGNIGSIDDDKQAAMRYTEVKLAKIANYIIGDIKKKTVKFIPNFDDSETEPIVLPSMFPNLLVNGSRGIAIGMATEMPPHNLGEIIDACVYKIKHPKASYSELSNFVLGPDFPTGGVIKGTKGIAEALENGRNKIKLFCKYEIYTKGKNKFIEITEIPYGVVKVKLVYEIDLIIQNKLIDGIIEIKDRSDRDGINILITLDINSNEESILNYLFSKTQMQITYSYNNIVIDNNSPTLMNLENLISSYIAHIKNVKTLSLNYDLNKAKVRLEIINGFIKVSEITSQVIELIRKTQGSKMVVNNLIQVFNFTKLQAESIAELRLYKLSQTDKEIYLKEKVEVKETINIIENLLNNEKEFNNFLINEIKAIKKEFSVPRKTQIEEDFEVSYNKLDLVKEEIINVSISKNGFI-----KRFSDKVLENNEWKNYALKEKDNLVFFSKVNTVNFLLCFTNLGNYVIVAIYQIQEVKWKDLGNNINLFASRPDEEIVSVIEVSDFEENLSVMLGTKQGYFKRVMLKDFLVSRFTKKTAMPLNEDDYLIKAKLTNLDSYLVAITENSIISKFSESEIMFYSTKARGSKAIYFSVGDKLSNFTIASYGDEIFAFSSDLNYFYFNEADIVLTPKNIKGRNIFDKKYK.................................................................................... 748
19 0.000e+00UniRef50_M5RM44 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Rhodopirellula maiorica SM1 TaxID=1265738 RepID=M5RM44_9PLAN  ali  36  1.............................................................................................................................................................................................MATSIPPHNPTEVCEALIRLVDHPETTIDEICDIIPGPDFPTGGIVCGRAGIRRGYKTGRSTIVVRAKCRIEEMKGSRTIIVSEIPYQQYRDRVIEKIAALVNGDKIKGISGIRDESDLNEPRLVIELKRDGDPDVVLNQLYQYSPLQDTFSLIFLALVDGKPRELTIKEILQEFLRHRVTVIRRRTQFLLARARRRKHTVEGLLLALADIDKIIKTIRSSTNQAEAKKRLMENYTLTSVQTDAILRMTLGQLVNLEQEKLSGEHAALLTEIIDYLDILSSQERINGIIKDDLEEMKRRFGDKRRTEISHEELGNIDLEDLITEETMVVSISHRGYIKRTPTSVYNTQRRGGKGLKGAKTDDEDPIEHLFVASTHAYLLFLTTLGKVRWQKVYDLPQLARDSKGRAIVNLLNLSEDEKIAECLAIRDFDGYYVVMATRSGLVKKTPLEQYSRPKKGGIIAIKLREGDELVGAAVIGPGDEVILVTSSGMAIRFRESDARPMGRNTSGVKGIKLVGDDSVVGMVVADPEATLLTVCENGYGKRTHFARYRTQKRGGKGLRDIRTSERNGPVIGIARVTDEDELFMMTAKGKLQRIKAADINVIGRNTQGVRIMNIDSGDSLIAVVRVPPEEDEAEGLAAVAGDVVEGTVVE 718
20 0.000e+00UniRef50_R4LTG2 DNA topoisomerase (ATP-hydrolyzing) n=3 Tax=Actinobacteria TaxID=201174 RepID=R4LTG2_MYCTX  ali  37  4.......................................................................................................................................................................PTVLPSRFPNLLANGSGGIAVGMATNIPPHNLRELADAVFWALENHDADEEEVMGRVKGPDFPTAGLIVGSQGTADAYKTGRGSIRMRGVVEVEEDRGRTSLVITELPYQVNHDNFITSIAEQVRDGKLAGISNIEDQSDRVGLRIVIEIKRDAVAKVVINNLYKHTQLQTSFGANMLAIVDGVPRTLRLXQLIRYYVDHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVIALIRASETVDIARAGLIELLDIDEIQAQAILDMQLRRLAALEXXXXXXXXXXXXXXXXXXXXXLAKPERQRGIVRDELAEIVDRHGDDRRTRIIA-ADGDVSDEDLIAREDVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVTXSLGQADRLRLQSLGRNRGGQX----LRDNDELVGAVLCSADDDLLLVSANGQSIRFSATDLRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAEESGDDNAVDANGAD........ 677
21 0.000e+00UniRef50_A0A066YS72 DNA topoisomerase (ATP-hydrolyzing) n=52 Tax=root TaxID=1 RepID=A0A066YS72_9ACTN  ali  41  1MARRSSPTP--PPGDFEERILDVDVVDEMQGSFLEYAYSVIYSRALPDARDGLKPVHRRILYQANEMGLRPERGHVKCARLVGEVMGRLHPHGDASIYDAVVRMAQPFSMRLPLIDGHGNFGSLNDDPPAAMRYTESRLTAASMSMVESIHEDTVDFGPNYDGSEQEPQVLPAAYPNLLVNGATGIAVGMATNMPPHNLSEVVAAARHLIKHPNADLETLMRFVPGPDLPTGGRIVGLSGIRDAYESGRGTFKIRATATIENVTRRKGIVVTELPYTVGPEKVIGKIKDLVNAKKLQGIADVKDLTDRHGLRLVIEVKNGFVPEALLEQLYKLTPMEETFGINNVALVDGQPLTLGLKELLEVYVDHRFTVVKRRSDFRRRKRQDRLHLVEGLLVALVDIDEVIAIIRSSDDAAQAKDRLMERFGLSETQTAYILDTPLRRLTRFDXXXXXXXXXXXXXXXXXXXXXLESDTKLRSVVSSELGAVAKQFGTERRTVLLEVPSAALAVPLEVADDPCRVLLSSTGLLARTF--------DLEPVTDEPSRARHDVVASAVPATARGDIGVVTTAGRVLRLPVIDLPALPRAPRRCPAAPRSPSSS........................................................................................................................................................................................................................................... 600
22 0.000e+00UniRef50_A0A2W5XZE2 DNA gyrase subunit A (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2W5XZE2_9CHLR  ali  39  1............................................................................................................................................................................................GMATNIPPHNLDEVCDAVATLIDNPDMTVDELCEIVKGPDFPTGATIFRFEDIRHMYATGRGRIIMRAQVSFEEIRGRMAVVVTELPYQVNKTTLIEKMADLVGQKRITDVSDIRDESDRTGMRIVVEVKRDGSPHTVMQQLFKHTQLQTSFSANVLALVDGQPVTLGLKRLLEHYISYRREVVRRRTEFDLARAQERAHILEGLKIALDNLDEVIATIRASADTDAARQALVERFALSEAQANAILEMQLRRLAALERKKIEDEYEAVIRLIAALEELLANPRKISIAIKDELTELKKKYGNPRKTRIQADANRELTAEDLVAAEDVVVTLSQRGYIKRQAIDTFRSQRRGGRGRLAMLTREEDAVRHLLVANTHDNILFFTNRGRVFITKVHTLPEASRQAKGLPIINLPGVQQGEYVSAIIAMPFEPDHFMVMATRRGMIKKTSLAEYAKIRANGLIAINLVDGDELRWVGLTDGQSDIVLATRKGQAARFREAEVRPMGRDTMGVTGIRLRPKDEVIGMEVAVPAGQLLVVTEQGYGKRTALDDFPVKHRATGGVIANSLNHETGDVAAVRVVREDEELMLITQEGSILRTQVSSINRYRRPSRGVTVMKPGPGDRIVSIAVFVDDREPLPVEPEVDG......... 661
23 0.000e+00UniRef50_UPI0004D9C77C DNA topoisomerase 4 subunit A n=1 Tax=Clostridium novyi TaxID=1542 RepID=UPI0004D9C77C  ali  41  1MAKKN------INIPKDNNIIKASISEVMPDNYLPYAVEVAKERALPDVRDGLKPVHRRILYGAYKLKATPDKPYYKSARIVGDILGKYHPHGDTSVYDAMVILAQNFTTRIPLIDGHGNWGSIDGDSAAAMRYTEARLTNAAMEMLKDIDKEVVDMVNNYSDTELEPKVLPARFPNLLVNGAFGIAVGLATNIPPHNLKETIDGCIAYIDNNDISTKELMNYIKGPDLPTGGILIGEKALLSAYEKGEGRVTLRAKTNIEKLNDRYGIVITEFPYRKNKSKMLQTISEMTADKKLDAISDIRDESDRNGIRAVIELKKSANAERVLKYLFKKTELQCNLSFNMVAIADGKPKTLGLKAILKYYVEHQKDVVIRRTKKELEIAEKRFHIVEGFIKAIDIMDEILKTIRASKSKKDSEENLVNKFGFSKEQAEAIVELMLYKLTGLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXFKVIKKELNEVKENYGDERRTNIIDDEKAKIDIEELILDEDVIITISNEGYIKRVSEKYYKRINPKVED---IEYREGDFNKAILEGNTKYSLIIFTDEGNLYQLRIVNIAEMKWKEKGERLDNLIKTLDLEKINFYVIEELNSHKNFIFFSDRGMMKKSSLDKFKT-NYSKLLALKLKENEKLINVKLADNNQYIKVQTKNGLKFTVGE........................................................................................................................................................... 689
24 0.000e+00UniRef50_A0A0S8CYG1 DNA gyrase subunit A (Fragment) n=4 Tax=root TaxID=1 RepID=A0A0S8CYG1_9PROT  ali  37  2.......................................................................................................................................................................................................................TLDELIEIVPGPDFPTRGIIYGTAGIREAYRTGRGRVVMRARTHFEEKSGRQAIIVDELPYQVNKSALLIRIGELVREKRIEGISEIRDESDKSGMRVVLELKRSEIPEVILNNLYKDTQLQDTFGMNMVALVDGQPRLLNLRQIIDEFIRHRREVVTRRSVFELRKARERGHVLEGLAVALSNVDEIIALIKAAPAPADAKQQLMVRTWFSDVQAQRILEMQLQRLTGLEQRKIEEEYREVMDTIADLLDILATPERIRTIIADELKQTRQEFADARRSEI-EQNAQEISLEDLIAPEDVVVTLSHTGYIKAQPLDDYRAQKRGGRGKQAAKTKEDDFIDSLFIAHTHDYILCFSDRGRLYWLKVYEVPQGARTSRGKPIVNVVQLAEDEKITAILPVKEFDDGHFFMATANGTVKKTPLSDFSRPRQMGIRAVDLDEGDYLIGVALTNGHHDIMLFSDAGKAVRFSEQDVRPMGRTARGVRGMRLGPDHQLISLVAVEDEQLVLTATENGFGKRTQVAEYTRHGRGTQGMIAIQTTARNGRVVAARLVANDDEIMLITTGGVLIRTHVSEIREMGRATQGVRLINLGEDEHLAGLEKIVDKDDEQEENGKAVGESGPAPET. 661
25 0.000e+00UniRef50_A0A0G0ZH63 DNA topoisomerase (ATP-hydrolyzing) n=5 Tax=root TaxID=1 RepID=A0A0G0ZH63_9BACT  ali  46  1MAKNDEKITSLTNGDGNPTLLRTDITKEMQSAYLDYAMSVIVSRALPDVRDGLKPVHRRIIYAMQDQGMVASGKFHKSAAVVGEVLKKYHPHGDVAVYDSMVRMAQDFSLRYPLIIPQGNFGSVDGDPPAAMRYTECKMAKISEDLYADIDKETVNFEMN-DLQNLEPIYLPSRLPNLLLNGASGIAVGMATNIPPHNLIEVIDGLQHMIEKADNNVEDLIQFIKGPDFPTGGIIYDQKEIMQMYATGKGKVVTRAKMDIEEDRRGRTIIVTEIPYQINKATLVAKIADLVKNKRIEGISDLRDESNRHGMRIMIELRKEAVPKKIQNQLYKYTPLQNTFNANMVALIDNEPKLMTLKMILEEFIKHRQQIVIRRTIYLLKKAREREHILLGLKIALDNLDEVIALIRKSKDAETAKAGLMSKFALSEIQAQAILDMQLRKLAALERQKIEDELKQIQETIKGYEMILISPKKIIDVVSKELKEVREKYGDVRKTKVIKGKVGELSEEDLIVKQK.................................................................................................................................................................................................................................................................................................................................... 544
26 0.000e+00UniRef50_UPI000664DDD9 DNA gyrase subunit A n=1 Tax=Neisseria meningitidis TaxID=487 RepID=UPI000664DDD9  ali  39  1...................................................................................................................................................................................VNGSSGIAVGMATNIPPHNLTDTINACLRLLDEPETEIDELINILQAPDFPTGATIYGLSGVREGYKTGRGRVVMRGKTHIEKNGEREAIIIDEIPYQVNKAKLVEKIGELVREKTLEGVSDLRDESDKSGMRVVIELKRNENAEVVLNQLYKLTQLQDSFGINMVALVDGQPRLLNLKQILAEFLRHRREVVTRRTLFRLKKARHEGHIAEGKAIALSNIDEMIRLIKESADAPEAKEKLLSRAWLSEIQADAILRMSLRNLTGLDQEEIVGDYKNIMAKIIDYLDILAKPERITQIIREELEETKTNFGDERRSEINPF-GGDIADEDLIPQREMVVTLTHGGYIKTQPTTDYQAQRRGGRGKQAAATKDEDFIETLFVANTHDYLMCFTNLGKCHWIKVYKLPEGGRNSRGRPINNVIQLEEGEKVSAILAVREFPDQYVFFATAQGMVKKVQLSAFKNVRSQGIKAIALKEGDYLVGAAQTSGSDDIMLFSNLGKAIRFNEHGVRPSGRGSGGLRGMRLPADGKIVSLITFAPEAQVLTATANGYGKRTPIADYSRKNKGGQGNIAINTGERNGDLVAATLVGETDDLMLITSGGVLIRTKVEQIRETGRAAAGVRLINLDEGETLVSLERVAEEAEDENPEVENPEDNEAE.... 738
27 0.000e+00UniRef50_Q6KHI4 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Mycoplasma mobile (strain ATCC 43663 / 163K / NCTC 11711) TaxID=267748 RepID=Q6KHI4_MYCMO  ali  33  1..........MKTNELKDKFLLQSLDGIMSNRYGVYAKYIIQQRALPDVRDGLKPVQRRILYSMHELGLTSEKPFKKSARVVGDVIGKYHPHGDSSIYEAMVRMSQEWKMNVPLIQMHGNIGSIDDDPAAAMRYTEARLSKISSLLLSDIKSDTVSFSLNFDDSEKEPTVLPAFFPNLLVNGARGIAAGFATEIPPHNLGEVIDGIIAKIKNPNIKIETLNTIIKGPDFPTGGIIYGIDGIKEAAFSGRGRITITSKYEVHK----NQIVITEIPYGVVKSKLVRQIDEINLDKNIGGMNEVRDETNRDGIKIVIDLEAGADASKIMKFLMQKTELQLYYSYNNIAIHNNAPVLMNLHDLIQAFLDHVKVIQTNKINFELEKLSKRLEIIEGFIKLTEISDQVIEMIRKSEGSKVVVENLIKIFNFSEIQAESIANLRLYRLSKTDVEEFIKEKQELETRINFLKTLLSSESEFNAELIKIFKDIKKTYATPRKTEIKDQALKDVSLSDLIQAEETFVGISRDGYI-----KRFNQKIHDSNEMQTYLLKEDDALIFLSKTLTTGKLLIFTNQGNYISIPIFKIAEEKWKNLGIHLNDFATLLPNEFLIKVLYVDDFSKDFSITITKKGFGKKVQLPEFEVSRNKSYPAIKFKDGDELLNAFITNDRLDILLVNTKLEVYKFSENDFKTYGIKAAGVKISDNATKFEISAAIAYSQNDTLVFLTESGHARKINPKKVDILN--QKSIKTFLSTKPSGKIIKIFNLNDNVDLAIRTTD-SIVTINTKEISETNLHTKGIYGISLGDNSKLISIENLIPEQKVKLEKDKQNLKFEDDQI.. 834
28 0.000e+00UniRef50_A0A0B3AWZ5 DNA gyrase subunit A n=5 Tax=cellular organisms TaxID=131567 RepID=A0A0B3AWZ5_9ARCH  ali  44  1MTDSNKTDDETQKKLTEEKVIQTEISSEMKKAYLDYAMSVIVSRAIPSVEDGLKPVQRRILYAMQQLGLKPNSQTKKSARIVGDVIGKYHPHGDTAVYEAMVRMAQDFSLRYPLVFGQGNFGSVDGDSAAAMRYTEARIMDISSELLQDLEKETVNFVPNYDNSLKEPELLPGKLPNLLLNGASGIAVGMATTIPPHNLTEVCDAIIAYIKNKEITFEELCEIIKGPDFPTGGSVQG--DMLELYKTGIGKLIMRGKITTENFKNKEAIIITEIPYMLNKTILVTQIANLVQEKKLKDISDLRDESSRGKTRIVIELKKGVNSNFVINALYKYTRVQDSFNVNLLALHSGQPKVMNLKEVIDAYVNYRKLIITNRSKYELKRAKERQEIVQGLLIALNDIDGAVALIKKSKSAVEASEGLIKKYKLTKVQAQAILDIKLQQLTSLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXLKIIIKEVRELKEKYGDNRKTQILKRQIGEISEKDLIQKKEVTITITEKGYCKRMDVKDYKEQYNKRK......................................................................................................................................................................................................................................................................................................... 541
29 0.000e+00UniRef50_F9P6A1 DNA topoisomerase (ATP-hydrolyzing) n=9 Tax=Terrabacteria group TaxID=1783272 RepID=F9P6A1_STRCV  ali  39  1......................MSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRILYSMNKDGNTFDKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMHGNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKDTVPFAWNFDDTEKEPTVLPAAFPNLLVNGATGISAGYATDIPPHNLAEVIDAVVYMIDHPKAKVDKLMEFLPGPDFPTGAIVQGRDEIKKAYETGKGRVVVRSRTEIEKLKGKEQIVVTEIPYEINKAVLVKKIDDVRVNSKVAGIAEVRDESDRDGLRIAIELKKDANTELILNYLFKYTDLQINYNFNMVPIDHFTPRLVGIVPILTSYIAHRKEIILARSRFDKTKAEKRLHIVEGLIRVISILDEVIALIRASENKSDAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLEEEEAELREKIAMLSAIIGDERTMYNLMKRELREVKKKFGNPRLSELQDTNAIEIDTASLIVEEETYVSVTRGGYIKRTSPRSFNSSTVDEVGKR-----EDDRLIFVSSAKTTQHLLIFTNLGNVIYRPVHELADIRWKEIGEHLSQITNFETNEEVLYAELVDNFDEGTYFAVTKLGQIKRVERKEFSPWRTYKSKSVKF........................................................................................................................................................................................... 628
30 0.000e+00UniRef50_A0A0E9DAY6 DNA topoisomerase (ATP-hydrolyzing) n=3 Tax=Chlamydia TaxID=810 RepID=A0A0E9DAY6_CHLTH  ali  56  59..KEGYTVQSQILDSEENGLRPADLATVMKNSFLEYAMSVIVARALPDARDGLKPVHRRILYGMSELGMFHNVQHKKSARIVGDVLGKYHPHGDSSVYEAMVRMAQDFSLRYPLIDGHGNFGSIDGDSAAAMRYTEARMSKIAGAMVDGIKKNTVDFIDNYDGTEKEPVVLPSRFPNLLVSGSYGIAVGMATSIPPHNLGEVIDGVCALAKNPDITIAELMQYIQGPDFPTGGIIFDKEGLIRAYETGVGRVTIRSKATIELSNGKSKILITEIPYGKNKSSLIESISHLIKDKKIEGISDFRDESNRDGIRIVIEIKKNYVPEVILNKLFKLTEFQTRFSFNMVALVNNEPQKLNLKSALEVYLQHQINVVTRRLQFDLEKDLARAHILEGLKICVENIDRVIAIIKQSKTDAEAQKKLGDEFNLTEIQTKAVVDMRLGRLTGLAXXXXXXXXXXXXXXXXXXXXXLGDKNALIDLIIKELQELKEAYGDKRKSEI...................................................................................................................................................................................................................................................................................................................................................... 554
31 0.000e+00UniRef50_A0A0G0WVD1 DNA topoisomerase (ATP-hydrolyzing) n=11 Tax=Bacteria TaxID=2 RepID=A0A0G0WVD1_9BACT  ali  45  2..DMTDKVAEKENSKENDKILPVDIITEMKESYLAYAMSVITSRALPDVRDGLKPVHRRILFAMSELGLTASSRFRKSAAVVGDVLGKYHPHGDTAVYDSMVGMAQEFSYRYPFILGQGNFGSIDGDNAAAMRYTEAKMSKISAELMKDLEKETVDFRPNYDQTRKEPIVFPASVPALLLNGTLGIAVGMATNIPPHNLAEVLDATNHLIENEDASTEDLMQFIKGPDFPVGGIAYGSKDMLHAYSSGRGGVVCRGEAEIEQKSGNFQIVITSIPFRVNKSNLIMAIAELVQEKKLEGIKGLRDESTKD-IRVVIDLKSGAHPEKVLNYIYKNTQLESNFNFNMVALVEGVPQTLSLKSILALFIAHRKEVVKRRSIYDLRKAEEREHILLGLKKALDFIDKVIKTIRTSKDGPTAKLALMKEFKFSDLQAVAILEMKLQKLAGLERKLXXXXXXXXXXXXXXXXXXXXXPKKMLKVIATEL..................................................................................................................................................................................................................................................................................................................................................................... 481
32 0.000e+00UniRef50_A0A257A104 DNA gyrase subunit A (Fragment) n=4 Tax=cellular organisms TaxID=131567 RepID=A0A257A104_9EURY  ali  55  2..................RISEISIDEEMKNSYMDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLYHNKPYKKSARIVGEVMGKYHPHGDQAIYNTLARMAQDFSMRYVLVDGQGNFGSVDGDAPAAMRYTEARLSRLAEEMLKDIDMETVDFMPNFDGTLKEPVVLPAKIPNLLVNGASGIAVGMATNMAPHNLGEVVDALIHLIDNPDADVIELLNFVKGPDFPTGGMVIGYEGLINAYKEGRGKIKIRAKYRIEGDK----IIIYEIPYEVNKSNLLKKIASLVREDKLRGISDLRDESDREGIRIVVKVKRDMNPEIVINQLLEHTDLEVTYGIINLVLVDGVPKILNLKELMQEYLRHRMEVLIRKLNYRLKKAKERKHIVEGLVKALGMIDEVIATIKASKNVKNAMGNLMD-MGFTEIQAKAILEMRLQKLTSMEIGALIEEDRKLGKEIEE........................................................................................................................................................................................................................................................................................................................................................................................ 441
33 0.000e+00UniRef50_A0A077L6W1 DNA topoisomerase (ATP-hydrolyzing) n=48 Tax=Bacteria TaxID=2 RepID=A0A077L6W1_9MOLU  ali  33  1MDKKNKN----NFEEIVENIIKKNMVEIMSDSFSRFSKYVIQQRAIPDARDGLKPVQRRILFSMWNLKLRNNDPFKKSARIVGDVLGKYHPHGDSSVYEAMVRMAQEWKSNYPLVEMHGNKGSIDNDPAAAMRYTESRLQKITELMLKDLEKKVVPMVPNFDDSEYEPLILPTLFPNLLVNGAIGISSGFATQIPPHNLSELLEATIAMIKKPNITVEELMQYVKGPDFPTGGIIFGNQGIVDSFKTGKGKVTLSSKYQFVKDKKDNIIEITEIPFGVIKSKMVFEIDSIISSKTISGIKEIRDQSDRNGLSIYIELNEGSNAEAILNYLMNKTNMRINYDYNMLAIYKNAPTLLTLDLALFAFLEHLTEINTHSIKYDWQKYTLRLEIVKGFIKVAEISDDVIKLIKESDNRKGVILALKETFNFTEIQATAIAELRLYKLSKMDQMEFQKEKNNLEILIKRCDALLNDKYEFDNFLINQLNEIKKEYGTARKTEIREIVNKGVDLKLLAKNEDFYFFISEQGYIKKISNKIYNSN-----DLNTYKLKENDTIKYYDKINSLSKLLFFTNKGNFFVLEAHILKDNSWKELGQHISSFVNIEANEKIIRVMEITSYNSYNLILITKYGYGKKVKIINFDSKTNKSKTCISFKQDDELIDAKISNDEKDIFIILNNGSYFLINENIFSTLALRAQGIKLLQTNEKTFISAFTTCSKINKVTMLTEGGMFKQWNMSEIEYTNRTNRGSKLYNFLKNVNCIPKCLEVNTKEELLYTNKNNESSIFKFE--KMTKDKTKNDKLINLD................................... 805
34 0.000e+00UniRef50_A0A257QIH0 DNA gyrase subunit A (Fragment) n=3 Tax=Bacteria TaxID=2 RepID=A0A257QIH0_9BACT  ali  46  4...............DKEVLIPTSITEVMQTAYIDYSMSVIISRALPDVRDGLKPVQRRVLYAMLREGLVHNRAFDKCAGVVGEVLKNYHPHGDASVYDTLVRMAQTWVMRQPLIDPQGNFGSVDGDSAAAYRYTECRLTEAAEALLGELDEDTVDFIPNYKESTTEPSVLPAGLPNLLMNGSTGIAVGMTTNIPPHNLGELIDAICELIDHPNATVEDLMRYLPGPDFPTGGIISGRDGIRQYMKTGRGIVKMRGVAHVESLKGKEQVVITELPYNVNRANLVTQIAGLVSDKVLDEVSDLRDESDKQ-TRIVIELKRGEIPKVVVNKLFKHTPLESSFGVILLAIDKRRPKQMNIKELLECFIDHRREVIYRRTQFLLRKAEDRAHILEGYKIALDNLDDFVKIIRASANREEAKIALMQKYPLSERQTNAILDLRLYQLTGMERGKIEEEYAELMRLIAEYNEI.................................................................................................................................................................................................................................................................................................................................................................................... 455
35 0.000e+00UniRef50_A0A0X8HDL8 DNA topoisomerase (ATP-hydrolyzing) n=37 Tax=root TaxID=1 RepID=A0A0X8HDL8_9GAMM  ali  44  7..................EILPVNIEDELKQSYLDYAMSVIIGRALPDVRDGLKPVHRRVLFAMHELSNDWNKPYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQHFSMRHVLVDGQGNFGSIDGDNAAAMRYTEVRMARLAHELLADLEKDTVDWVDNYDGTERIPDVLPTKVPNLLINGSSGIAVGMATNIPPHNMVEIISGCLALIDDYTLSVDDLMEYIPGPDFPTGAIINGKAGILEAYRTGRGRIYVRACHTIEDKSGRDHIIVTELPYQVNKARLIEKIAELVKEKKIEGIAELRDESDKDGLRVVIEVKRGESGEVVVNNLFAQTQLQNVFGINMVAIEDGQPKILNLKEILEAFIRHRREVVTRRTLFELKKARERGHLLEGLAVAISNIDEVIELIKASPSAAEAKEKLLDKVW----QPGQVTDMLERAGATSCKPEELEEGFGLNQTGSEYRL---SPAQAQAILELRLLAQSIAIHQEKHSAKALGLQKTINQPDNGASLPSPGGHGQQGSLRTLLQSPFHRVDGTFXC........................................................................................................................................................................................................................................................................................................ 526
36 0.000e+00UniRef50_A0A2E6EME3 DNA topoisomerase (ATP-hydrolyzing) n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A2E6EME3_9RICK  ali  32  36.....................NVSLLEATRERYLNYALSVITSRALPDVRDGFKPVQRRILYAMYNLRLLHTARFRKSAAVVGEVMARFHPHGDQSIYDAMVRQAQPFALRYPLVEGHGNFGSLDGDPPAAMRYTEARLRALASEMLEEIDRNTVAFRDNYDGTTKEPIVLPSRVPQLLVNGCTGIAVGMATNIPPHNLREVCSAAVALIDEPKSDVAALMRHIDGPDFPMGGEILNPEELGQLYETGRGTVKTRATYHIEKANRRRYIVITSIPFGQNKANVVEQIGDLIRDNKVPQLTDVRDESTDD-IRIVCELKRGAVDTVAMAYLYKHTNLQTNFHVNMTVLLPGTPAQVGLVTVLRHFLDFRFEVVKRRFEYDLARLERRIHILKGFAILFDALDEAIALIRASDGRKDAAKRLMKRFPLDEEQTDAILDLKLXXXXXXXXXXXXXXXXXXXXXAKRIRGILRSGKKLWGVVRDELMEVSHTHGDERRTLVASADDFVFDAEKYIVKEDTWLIFTRDGWVKRQ---------RGFSDVSTIRVREGDAVMCAFRASTRSTVAFFSDLGKAYVLGLDKVSQTSGYGEP--VQRYFKLADGEKIVSVVSMDERNLPEYHQVTEAG-ASEDDTETLRSTASQGPEPDPSTEDTQQASAEDAQDWEEVVALTRAGKGLIFPLSNHEESSTRS-GRKYCSLRKVKGIVDGVVTGPDFKLSLATYQGRVLIFPVEQLKLLRSTGMGVNTIRLGSGDYVIDFELNAKRSRGLEIETSRGRQVRISERRYSVTRRGGKGVEVIK..................................... 839
37 0.000e+00UniRef50_A0A2T1FQI4 DNA topoisomerase IV (Fragment) n=3 Tax=Cyanobacteria TaxID=1117 RepID=A0A2T1FQI4_9CYAN  ali  47  1MAKQLN--------LLSGQVISTPLHAEMQQSYLEYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDRPYRKCARVVGDVLGKYHPHGDQSVYDALVRMVQEFSSRYPLLAGHGNFGSVDNDPAAAMRYTETRLAPIAHEMLTQVGDATVDFADNFDSSQQEPTALPAQLPFLLLNGCTGIAVGMATNIPPHNLGEVVDGLIALIENPELSDEKLMQLIPGPDFPTGGEIVATEGIFDAYTKGKGSIAVRGVAGVEEVPGNRAIVVTEFPFQVNKAGWIEKVAELVNAGRLDGISDLRDESDRDGIRVVIELKREFTPEAVLARLYQQTDLQTNFGAILLAIVNGQPRQLTLRQLLQEFLDFRELTLTRRYNYELQAAGRRCHILEGLMLALTNLDTAIDILRNSPDGTTAKQTFQVRLNLSESQSDAILAMPMRRLTGME......................................................................................................................................................................................................................................................................................................................................................................................................... 445
38 0.000e+00UniRef50_UPI0006CA6C0B hypothetical protein n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI0006CA6C0B  ali  32  7...............ENHDYPTVELCSHTSNSWIDYTKYVLVDRALPDSVDGLKPVHRRILFAQQVMGNNSNKAYKKSARIVGDVLGKYHPHGDGAVYQSLVRMAQPWVMSAPLSDGQGNWGNQDRDNAAAMRYTEVRMTSYAEGMFTDLTKDTAVWEDNYDATEVAPTQLPTRHPNLIVNGSEGIAVGMACSLPPHHPIEALNVVKHLISGEEVELAELKKIMPAPDVPTGGIVHDLEDMETAWLEGVGHVRVRSVWHEELVNSRKAIVITAIPYGITPKSVILQVEEAKKGSDKEEIAQFRDENDEHGLRIVIELSSGAEPEIVFNKLCSITKLDAAIHYNVNVVHNKRPEKMGLLSLFNIFIDSREKVIRIRTQKELEKAQGRLHILAGFEKAFTDIDGLIATIRANKTKAEANVAIQEQFGIDEVQANAVLEISLTKLTSGELGAIIEEADQLRLKVEGFEKILGDMSVLREVILSESDEQIQKLLTAKRRSDFSYDKIILSPEDLAKEEFCSIFMSQKGFIRIVPNTFMKAQRRGTVGNKHMELRKGDILEKSIDCFSHDYIAFMTTKGRVGFCRAFELSTLEKGQHVNNFIKLGEGEEVTQIAAISKETLHGSYVLTTATKMGIIKQTPLDSFNPNVKRTVRAINLSEDDQVAFFGVATESATILLSASNNKTVKFKLDSIRETSRTSRGVKAMNIDKEEGVVSGIVVEDEDDMLMVSTDGIMKLSSISSYRETARGTKGVTTMKL-KEGASILAAFAVPESEDVITMSSKSMANRVSLEHFSAQNRATMGMRLVKVANKDTLISATLVRKEEE................... 845
39 0.000e+00UniRef50_F0V2P7 DNA topoisomerase (ATP-hydrolyzing) n=3 Tax=Mycoplasma TaxID=2093 RepID=F0V2P7_MYCS3  ali  37  5..KPSSKLEKILEGLPSSNVENKDISVVCDESFLNYSLSVITSRALPDLKDGLKPVHRRILYAAYEEKLFNDSRFKKSATLVGAVMGSYHPHGDKSIYDALVRLSQDFKMRYPLLEGQGNFGSIDGDVPAAMRYTEIKLSKFGEKFLSGIKEECVDFVDNYDGSKQEPSILPVIVPSILLNGSEGIAVGMATKIPPHNLREVCDAIIALIDNPELQDEQFIEYIKGPDFPTGGEIIGIESVKRYHSKGLGKIILRSKVEI--DANKHQLIIKEIPFGIKKADLIKKIADLAYEGKNAFLQNIRDESNKEGIRLIIECKKGSDLKAVLNNLYKYARLQVTFAVNLTLLVDGKPQLLGIGAIIRNYLQHQLDMLQRKTKFNLREVQRRIHLLEGRETVVRNLDEVIRIITDEDNPEVI---IQEKYSLTPVQIKDIFDLPLRQLKKIEFLKLTNEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFKNDRKTLITPKGIAKITKWDCIPKEDIILKVTQNNYIAAIPLDKIDLTHRNTVGNSSSEFKTGDLDVDLLLSSSHDDLFIFTNYARVFKLKAHEIKNKKWSKKPQKLNNLIPMGKDEKAVKIINEEKWKDIDLLFATKFGFIRKISFYKFEKKWKSGKTAMRLSENDQLKFVIKMHKDSEILLASSKNKVIRFKSSILEAKRRKTFGVRGINLRNDDELISASSTYDGDQLLSLVESGKGKITSLDEIKLSKKGGKGVLAYK-NKENEKLIACVLIKDSDQILLMTNKDHINRFQASQISVRKRRTEGSQLISLKPNEKLVFFAKYQLPDDIE................. 894
40 0.000e+00UniRef50_I4CE97 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1) TaxID=706587 RepID=I4CE97_DE  ali  34  23.....................ETPLHEEVEKRYLAYALSTIVSRALPDVRDGLKPVHRRILYAMHSMRLSDTAKMRKSAAVVGEVIGKYHPHGDQAAYDAMVRMAQDFSLRYPLIDGSGNFGSLDGDSPAAMRYTETRLSQFASLLLKEIDQGTTDFRATYDAMGEEPDIFPAMIPNLLLNGASGIAVGMSCSFPPHNLLEIVAACRAAIKKRDIDSSELLQYVKGPDFPTGGEILDEVGLAEVYRTGHGSVRVRGSFHTEKTRGREDIIIDSIPYSVNKARLIERIAQLIRDKKLRLVQDVRDESTADVRIVLELRGADVSVESVMAFLYKHTDLQINFPINFIAITPGVPDRLGLASIIRYFLDFRYEKTVRRLNHRLETLLKRIHILEGFDILFQDLDKALAIIRAARSRHEAEQGLKEAFHLDDEQIEAILEMRLYRLVGMEIGKLLDELSAKRKEASDIRKDLASPERLWKIIDRELADIESHFGDTRRTRIVQTHQAAATDYEFVDHEDTTVILSKLGWI--------RRMKSEVEDESTLKFREADNLFGLARVNTAETIAIFTNFGKVYVIRALDVPPSVSGYNYGDLSQVSLFQADEGELEFHEKAPPLVGRAILVTKTGQGFRFDYNQVQEPTKRGRRLVVLKKDDEVLTVKPESGNLAVIAADS-GRLLMFPLDQIPVLSGPGLGVRLMKLSPESRVIALETVRSEDSVRITRKRGKEKIIDVQEIALGQRASVGKANF......................................................................................... 792
41 0.000e+00UniRef50_A0A2K2VV51 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Desulfobacteraceae bacterium TaxID=2049433 RepID=A0A2K2VV51_9DELT  ali  35  8........................LHEEVESRYLAYALSTIVSRALPDVRDGLKPVHRRIIYAMDAIGAKQAARHVKSARVVGEVIGKYHPHGDAAVYDAMVRMAQDFSLRYPLVDGQGNFGSVDGDGAAAMRYTEAKLSAIAGELLADLKAQTVAFSDNYDGTLTEPAVLPARIPNLLINGSSGIAVGMATNIPPHNLSEVCDALINLIGNEDASTAEIMAKIKGPDFPTGGIIVSAEEMKEIYRRGKGSIKIRGEFEVETLKGRRQLVITSLPYSVNKSRLVEKIADLILSKKLPMVTDVKDES-AESVRVVLELRDGVDPQKVMTFLYKHSDMEINFPLNFTCLTPATPERLSIKEILNHFLDFRKEVVVGKLEFERASLEKRIHILQGFMKIFVDLDAAIAIIRVAENRAEAHENLKARFDLDDEQTKAILDLRLHALVRMEXXXXXXXXXXXXXXXXXXXXXLASREKIWREVGKEIAAVKKAYGDKRRTVIAGRPQLAYDKEDFVVHEDVYVVLTRNGWLKRVKSYDPRTQL----------LKEGDEVLAVINANTKETVAFFSNFGKVYGSRIYDLDVSGKGYGD-PIQTLFHFQDQESIVAVLPAPEPPPPLCLVATRNGTGFCFERSSLRASTRSGRTLIRLRPGDEVVAVRPVERP-LLAIATSR-RLLMTPVAQVSVLAGAGRGMRLIKP-DPPGVMDFFTVSKDDYLLIQSKKGKVNELAVAEQPIYNRGTKG............................................................................................. 763
42 0.000e+00UniRef50_A0A0G1V3X4 DNA topoisomerase (ATP-hydrolyzing) n=4 Tax=cellular organisms TaxID=131567 RepID=A0A0G1V3X4_9BACT  ali  50  2......PDTAPDQLPDNPRIIQAEITDEMQKNFLDYAMSVIVARALPDVRDGLKPVHRRILYACHDMGLKYSGKHSKSAKIVGEVLGKYHPHGDVPVYDALVRLAQEFSMRYPLIDGQGNFGSIDGDSPAAMRYTEAKLSKISEEMLVDLDKETVDLLDNFDGTLKEPIFLPAKLPNLLLMGSEGIAVGMATKIPPHHLGEVVDAIVHLVENPEASVEELMQFVKGPDFPTHGAIYDSKAIAEVYATGRGRIVVRGKAEIEETKGKNQIIISELPYQVNKAELVARIADLVHNKKIDGISDLRDESDRDGIRVVIELKRDAKPKALLNNLYKHTALQTTFPANIVALVDGTPQVLGLKQILSEYIKHRQLVITRRSEYDLRRARERAHILEGLKIALDHLDAVIKTIRESADSDVAKKNLMERFGLTEIQAVAILDMQLRRLAALEKK....................................................................................................................................................................................................................................................................................................................................................................................................... 444
43 0.000e+00UniRef50_Q83G39 DNA topoisomerase (ATP-hydrolyzing) n=5 Tax=Tropheryma whipplei TaxID=2039 RepID=Q83G39_TROWT  ali  33  5...DKDIPEIFDVISDNEKITDVDLLHQMQDSFLEYAYSVIHSRALPDARDGLKPVQRRILYTMSRMGLSPDKAHVKCARVTGEVMGKLHPHGDAAIYDTLVRMSQDFTMRIPLIDGHGNFGSL-NDGPAASRYTEARLSRAAVAMINDLESNVVDFVPNYDNQFTQPEVLPALLPNLIVNGSSGIAVGMATSIPPHNLQETVRAAIYLVRNRQSSLEQIMKILPGPDFPTGSIIVGKEAFKEIYATGKGSFKIRAKISIDYAGGHTNLVITELPYMVGSERVIEKIKQGVNAHRIDGILDVTDLSDRNGLKLVIGIKPNFSPNEVMDNLYRHTPLEESFSVNSVALIDGKPKTLGMLDMLKVFIDHRVCVITRRSKFYLATHKKRLHMIDGLLLALVDIDKTISIIRNSEGIKEARKNLMKCLNVTRDQAEYILDIRLNMLTKLSTIKXXXXXXXXXXXXXXXXXXXXXPNKIDAILIDELKKVAQRLPSPRRTILES----SVKSKKQKTDYPRQVVLTTNGFIFTIEVNNDLISELSQPETFDMAFNTHSEVKSSIVCGVRSRIGALTSAGKVIPFTPIGLPVLDSGFVTAKSFLGLENDEE----AVLLFELHQKESLAIATSSGIVKRVTPAIWPDRTER---VITLSAGDRVVGARGVSSCGYFVFITAKGNLLHYSAGLVNPQNRPARGVAGVTKDDDDRVISFGYTEDVDRANVLTVSKRMTTSRLSSYQTRGRATRGVQCHKFLKGEEWLHAAIV---GENLAAIDNLGNVVAIGKS--SVTAKSCAGVKQYRLP................................... 796
44 0.000e+00UniRef50_R6XWC0 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Firmicutes bacterium CAG:345 TaxID=1263020 RepID=R6XWC0_9FIRM  ali  32  1.......MKSKKSETILERIDKLPMPDVLIDSFNRYAKEVILDRAIPDARDGLKPVQRRIVFSMWRDGNTHNKPTVKCARSVGNVLGHFHPHGDSSVYDAMVRLSQDWKMNVPLLEFQGNNGSIDNDPAAAYRYTESRLSAMADFMVQDIEKNTVDMMLNFDDTVKEPIVLPSRFPNLLVNGSQGIAVGAVTNIPTHNLGEVIDATVYRLEHKRATVSDMRQFILGPDFPTGGIIDDVDALNNLYETGQGSFYIHCT--VDSTSEKGKIILTDIPYGEIKSTLVADLDKRRIESHLDSVVEVRDESTED-IRIVIELKKDANPEPVINFYRNKGALRSTFAANMLAIDKGHPKTMNLLEMIDAYIDHQKEVILRRSKFDFDKKSWRLSIVRGLIKAVSVLDEVIHIIRHSSGKEDSKNKLIERFQFTLEQAEAIVTLQLYRLSNTDVTILQEEEKTLIKELDDLKQTIENEDKLVRLIVADLKAIKKQYATPRKTKIEKIKTENVDQRSLIAKEDVMVVLTRDGYIKKTALRSYEASIQSSKGSDPFKLKVSDKTVFCQKTTTHANIVFFTNKGLYYSIPCHLISDAKWKEEGKHINNLVNLEPKEKIVSAFAVEDYKKGLYFALTSKGKIKRTEIIDFEKITTKGLRAMPLVDGDELVSAILTHGNSDIMVMTDQGQVSRYNENEVPIVSTKASGVKAINFSNEKSYITATLSYKNDEILILNDKNGARLLNSSVFPCFARLGQKTAACRIFKSSPTIISMDKIYRKKDVPCITENGLLVDLNSLEVSQLG---AGMKA-NLPENSKILGLCIIDENTPVEKAPEIISEPAKPKEKS. 845
45 0.000e+00UniRef50_Q6F1F6 DNA topoisomerase 4 subunit A n=67 Tax=Mollicutes TaxID=31969 RepID=Q6F1F6_MESFL  ali  31  1MAKKIDNSNIESEK----GIISYALEDLMGERFGRYAKYIIQERALPDARDGLKPVQRRILYAMNELNLTYDKPYKKSARVVGEVIGKYHPHGDTSIYDAMVRMSQWWKLGMPLIDMQGNNGSIDGDNAAAMRYTETRLAKISDLMLDDLNKNTVKFAPNFDDSEKEPTVLPSYFPNILVNGSTGIAAGYATNMPPHNLGEIIDATIKLIRTPNTRIDTILEIVKGPDFPTGGTVQGRNGIKDAFTTGKGKVIVNSKWHEEDNN----IIIDEIPYEVVKQDLVKKIGDVIDANPGLGILEVRDETDRNGLRIAIDLSDKANLDTVRKFLFKSTPLSISYNYNNVAIVDLQPKQLGIIELIHAYIAHYKEVFTFRTQFDLNKAEKRLEIILGLIKAMSILDQVISVIRSSTNRSDAIENLISKFVFSQPQAAAIVDMRLYRLTSTDXXXXXXXXXXXXXXXXXXXXXLNSEEVMDNEIINRLREVKKQFPTPRRSIVEDSIENDVEQKEVLVEHEYNLWISKDGY-----LKAIESKLISKNDPAVFGRKPNDMWIAAGEVSNLQHLILVTNKGTYYSIPLYKLPMSKWRDMGVHVNTIATMDPSEHIVSAFVVKDFAEQQILITSKNGNIKRIPVKDLEKIFTRAFRIMKLDAVDEIVSALITSKTRTCGIITRNGYGVRYHIEDIPVQGTNSKGVKAANLKEDYIVAGLGLTS-EDTIMYLTEKDGVKKFRNEDLPIYIRPKRGIRVLPERKRGTEYITFFNANEENIIKAIDTQDMYQEVNVNKYRHIELTSTGDFDIKDVAFASLSEINKVKPNDMPPGALNADDDAEGYVSKEE 834
46 0.000e+00UniRef50_A0A1E5IM74 DNA gyrase subunit A (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=A0A1E5IM74_9BACT  ali  40  1........................................................................................................................................................................................GIAVGMATNIPAHNIAEVSYALLALVDDEELSVSEIAKYIKGPDFPTGAIILGKSGIKDYMEKGRGSVKIRAKTEIEEVKGREAIIVNEIPYQVNKSNLITSIADLVRDKKINGIADLRDESDRDGIRIVIEIKKDANAQVVLNQLYKHTQLQSSFGVIMLALVNNRPKVMNIKEILMHHIDHRKVIIIRRTKFDLQKAEARSHILEGLKIAIDNIDAVIKIIKESADEDNARVSLISKFRLTKIQAEAILEMKIRQLTGLKRKEIDDEYLEVIKLIEKLHSVLADPNKVLDIIKNEVLDIKRKYGDKRRTQIQA-AEADFNIEDLIQEEEVAVTMSHAGYIKRISLDTYKAQHRGGRGIIAMNTKEEDFVENLFITSSHSYMLFFTTRGRLYWMRVYEIPEGSRTSKGKAMVNLLQLQTEEKITAAIPIEDIKDEYLLMCTRNGTIKKITLDKFINPRKRGIIAIELEDGDILTEVKAINKNPEIIIATKKGNAIRFKESGIRAIGRTGRGVKGIRLEKDDEVIGMEVFSPDDIFLSISENGYGKRTKVGKYRLQQRAGHGVINMQATKRNGNIVGIKKANDGEEVMIITQNGITIRLRVNSISVIGRNTQGVRLVRLDDGDKVAAIACVVKDENVEELQDAVEKVEKADKE.. 659
47 0.000e+00UniRef50_A7XYD9 GyrA (Fragment) n=11 Tax=root TaxID=1 RepID=A7XYD9_CHLTH  ali  46  3..............NKEEIIVPKNLEEEMKESYLRYSMSVIISRALPDARDGLKPSQRRILYAMKQLNLTPGVKHRKCAKICGDTSGDYHPHGERVIYPTLVRMAQDWAMRYPLVDGQGNFGSIDGDPAAAMRYTEARLTHSAIFLLEDLDKDTVDMVPNYDETKYEPVVFPSKFPNLLCNGSSGIAVGMATNIPPHNLGELIEATLLVLANSQTSIEDILEVMPGPDFPTGGIICGTEGIRSTYYTGRGKLRLRARMHVEENSDKQRIILTEMPYNVNKSRLIEQIAELINEKTLTGISDVRDESDKDGIRVVLELKKGESSEVVINRLYKFTDVQVTFGANMLALDKNLPRTMNIHRMISAWIRHRMDVIRRRTRYELNKAEARAHILEGFLKALSCMDEVVKTIRESSNKEHAKQQLVELFSFSEAQALAILELRLYQLTGLEADKVQKEYSELLEKITYYRKVLAEEELVKDIIREELQELHKVHKTPRRTKIE..................................................................................................................................................................................................................................................................................................................................................... 488
48 0.000e+00UniRef50_A0A287SQP9 Uncharacterized protein n=1 Tax=Hordeum vulgare subsp. vulgare TaxID=112509 RepID=A0A287SQP9_HORVV  ali  35  1......................................................................................................................................TECRLDPLTEAMFTDLELNTVDYVPNFDNSQKEPSLLPARVPSLLLNGSSGIAVGMATNIPPHNLGELVDALSAIIQNPDATLQELLEYMPGPDFPTGGILMGNDGILEAYRTGRGRIVMRGKTVIEEKTKRTAIIINEVPYQTNKSTLVQRIAELVEVQVLEGISDIRDESDRAGMRVVIEVKRGANPAIVLNNLYRHTALQSSFSCNMVAILDGHPKLMGLKEILQAFLDFRCSIIERRAKFKLSQALERKHIVEGIVIGLDNLDAVIQVIRETSNHTVAKEALAKEYGLSEKQAEALLDITLRKLTSLERKKFIDEANSLSESISKLNELLSSKKLMFQLIEQEAADLKSKFATPRRSFLEDSANGEVDDMDVIPNEEMLLILSEKGYLKRMNPNTFNLQNRGTIGKSVGKMRTNDNMSDFIVCQTHDHVLYFSDKGIVYSERAYKIPECTRVAAGTPLVQLLNLSDGERITSIVPVNKFEDQYLVMLTVNGYIKKVPLNAFASIRSTGIISMRLVPGDELKWVRLCRDDDLVALASQSGMVIVNTCNKLRPHGRTTRGMGAMRLKEDDKMAAMDIIPSTPWLLFIADNGYGKRVPLNAFRQSSFNRVGLRGYKLPEDC-RLAAVFVVGEDEQVVLVSHGGTINRIKVKDVSIQGRGAKGVILMRLEHAGKIQSASLISAADEEEISEE............. 720
49 0.000e+00UniRef50_A0A2E6DES4 DNA topoisomerase (ATP-hydrolyzing) n=4 Tax=Nitrospinae TaxID=1293497 RepID=A0A2E6DES4_9BACT  ali  34  2.................SNEKESDLQLELENRFLTYALSTIVSRSLPDVRDGLKPIHRRILYAMDSIGLNAAAKPVKSAKIIGEVLGKYHPHGDASTYESMVRMAQDFSMRYPLVDGKGNFGSIDGDSPAAYRYTEGKLTPITTYIFSDLKKETVEFQANYDNTIKEPMVLPSRVPNLLINGSSGIAVGMACSFPSHNLSEVMGALTALIKDQDATVAQLMKHIKGPDFPGGGIILNSKEIRKAYEQGSGAVKIRAEWKLEQLRGKEQIIIYAIPYGVNKARLIEKIAEIIIGKKLPPLMDVRDESD-EKMRIVLEVKTGTDTEKVMTYLLRHTDLENNFQLNFNCLKNGEPERLSLKEICRYFLDFRKEVVTRRLKYELALLIKRLHILDGFVAIFTELDKALKLIRSSKSKQEAHDKLKKAFKLDDEQVSAILEIPLYRLVSMEVEKIIAEQMEKMKEKKQIKATLKSDKKIWLIVQNELKEIDEKFGDKRRTKIKTIELVEYNAEDFIEHEDAYLVISKNGWLRKFK---------SLTDPSTLKYKENDNLLATAKANTRELVAFFTSRGMVYVHKVYNLSY-TRAGFGEPIQNFFKFADGEKVISMLSLDP-----AELATIAGKTHPERKSSSKSNRQT-----------RLGFAGETEGQLEGIAIGSSGYGFRFPITNLTETTK--AGRKLMTQKGDNRMIGFSLVT-GDHLFMASANGKGIVIPMDQVTVLTGAGMGSRMMKLVEST--LAGFKVTPKKGKATLVFDDGKKKEINLKDVRLCNRGGQGVIV....................................... 755
50 0.000e+00UniRef50_A0A1M3K0M6 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Chloroflexi bacterium 44-23 TaxID=1895927 RepID=A0A1M3K0M6_9CHLR  ali  32  1MADQNEEPEELI-------VQEHALDHFIEDAYRRYAVLTILDRALPDVRDGLKPGQRRILFAMGDMGLRHDTPHKKSARVVGEVLGKYHPHGDQSVYDAMVRMAQDFSMRAPLIDGQGNFGSIDGDSAAAMRYTEARLTSLGETMLADIEKDTVEWSPNFDGSLAEPDVLPTRFPNLLVNGVTGIAVGMSTSILPHNLGEVCDATKYVAQNEKITVPELMNFIPGPDLPTGGLLYRTDMIAQAYATGHSTLVCQAKADIHDIGGGKSIIITELPYQTQKATILERLASARE--KFVGITDVRDESDYLGMRVVFEVGRGVDPVDALDRLLANTQMRSSLSHNALALVNNEPKNLTLLDMIIEFIRHRLDVISRRSRFELEKAEERNHILEGLLKALSMIDEVVSIIRKSQNAETARRNLMDKLDLTGVQAQAILDMPLRRLVSLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXLEVVVEETEEIKDKYAEPRKTVIVDSEEGHMTVSDLVTPTEDQLIMVNDGGLQRIDSKGFRENVTKEK----PTSRAVFIPLLRAVAKPEETVLLISNQGRLWQGNSGRLPLAGTFDE-------LGLKRGEKV--IGLGVAQTDAKLILVTTAGQIKRVEMADVIGSRAEATWAIGLSGDEELLAAVVASDNAHVLICSAGPRVLRFESGSINPQATSAKGVTAIKMMGDP-LVSAVAIEPEGYCVAVTEKGHIKRVALEDFPVQGRGGQGVQLWKLTADTGKIVGFVAGSDKDQVDIYSARLKRVRIDIRALPIVTRATKG-----LDLGAKLVKGDLFADGE.................... 825
51 0.000e+00UniRef50_A0A0K2DQK9 DNA topoisomerase (ATP-hydrolyzing) n=5 Tax=Bacteroidetes TaxID=976 RepID=A0A0K2DQK9_9FLAO  ali  39  2.................EKIISINLEEEIKASYIDYSMSVIVSRALPDGKDGFKPVHRRVLYGMYEQGAF--KNYRKSARIVGYVLGKYHPHGDSSVYEAIVRMAQSWSLRYPLIDGQGNFGSIDNDPPAAMRYTEIKLQKVSEEMLFDLKKDTVDIKLNFDSSCKEPIVLPTVIPNLLINGSSGIAVGIATNMPPHNIVESINAICSYIDKTDISIEELMKDIIAPDFPTGGIIYGYEGVKKAFLTGRGKILLRSKVFFEKIGCCYCLIIKEIPYQIRKEDLIKKTLKLIKEEKLEGISKIRDESDRTGMRIVFYLKKNVNKHLLLKNIFKSTPLETTFSVNNIALVNGKPVQLNLKDIIKHFVNHRHEVLIRRSKFDLKNAKEKAHIIKGFYLVLDNIETVIELIKSSKEKNHAKKKLLIKFNLSEKQVQAILNLKLNSLTKLENEKIKKDYLKLKKDIYYYTNIKTDIFFQKKIIKKELKKIKEKYGDLRRTQI-DYLGIKSSLYDVIPNKKVVISHVGNG--------------------------KKDFLKQILVANNHQYMLFFTEKGFFFFLRVFEIPEGILIKRKKEDKICSSI----LVKNIKDKNYMKKKYVILITKFGLIKKTTLEQYTKKKNN---AINIKKGDSIIDAKLTDGKSEVIIAVKNGKIIRFHESTIEKLCLK------RFLLKEEKVIGMICINDKEYILVVSEKGFVKKYNLSPYIIV----KGIKRINLTDITGDLIAIKNVINKNDIIIINKSGLTIRITVEKI-----ATKSGKLINLKDNDKIADVA.......................... 748
52 0.000e+00UniRef50_A0A0T7KKK8 DNA topoisomerase (ATP-hydrolyzing) n=9 Tax=Bacteria TaxID=2 RepID=A0A0T7KKK8_STREE  ali  47  1.............................................................................................................................................................................................................MLALSHNPDITIAELMEYIPGPDFPTAGLILGRSGIRRAYETGRGSIMLRAKVEIEEKNGKQSIIVTELPYQVNKARLIEKIAELVRDKKIEGITDLRDESDRNGMRIVMEVRRDANANVLLNNLYKHTALQTSFGINMLSLVNGEPQVLNLKQNLYHYLEHQKVVIRRRTAYELEKAEARAHILEGLRIALDHLDEVITLIRSSKTADIAKQGLMERFGLSEKQAQAILDMRLQRLTGLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFNDKRRTEITIGGMEFIEDEDLIPEQNIAITLTHNGYIKRLPASTYKTQNRGGRGVQGMGTNDDDFVEHLLTTSTHDHILFFTNKGKVYRTKGYEIPEYSRTAKGLPIINLLGVDKGEWINAIIPIREFGDDQFLFFTKQGVSKRTPLSSFANIRTNGLIAISLREEDEVISVRLTSGDKDIIVGTSNGMLIRFNEQDVRSMGRNAAGVKAITLGDEDQVVGMEIVEEDVNVLIVTKNGYGKRTPIDEYRLQSRGGKGLKTCNITDKNGKLVAVKSVTGEEDIMLITAAGVIIRMPVDQISQMGRNTQGVRLIRLEEDQEVATVAKAQKD..................... 615
53 0.000e+00UniRef50_A5IXX2 DNA topoisomerase (ATP-hydrolyzing) n=40 Tax=Mycoplasma TaxID=2093 RepID=A5IXX2_MYCAP  ali  30  1MNKKKEQQLNDLL----SKIIQENLDTVVADRFSRYSKYVIQQRALPDVRDGLKPVQRRILYSMYDLGLQNNKPFKKSARVVGDVIGKYHPHGDTSIYDAMVRMGQEWKMGHTLVEMHGNVGSIDDDPAAAMRYTEVRLSEIANYVIGDIRKNTVKFAPNFDDSEKEPVVMPVLIPNLLINGSTGIASGFATEMPPHNLNEILDAAIAKVKNPAIELTKLAKIIQGPDFPTGGIIYGTEGIHEAFERGKGRITLASRYNVYTDSKYKYIEITEIPYGVVKSKLVHEIDLIVDSEEVAGLLEVKDQTDRNGINILITLDKEADENVIVNYLFLKTQMRIYYNYNNVVIDNYTPKTLGISALLDAYLKHVKDIKIKTIEFDLIKHKARLEIVIGFLKVAKITDKVIEVIRKSENSKQVIDNLMSAFDFTLNQATAIAELRLYKLSKTDEHAFLIEKEELEEKIKQCELLLNDSDEFNKYLIALFKDLKSKFGRARRTSIEEQIKASINQEDLVKEEQVFLGISKFGYIKKVSKKIYESNLINTYGIK-----EDDNILFYDNASSLDKLLLFTNFGNYAYLPVFKVHESKWKEFGTHLSDFVDLTSGEEVSAIKVSDFDSSNYVCLFTKKGQGKKVLLKEFDVSRFSKFVAMKLKSDDELIGAKLSNGLKDVLLITKNNFASLYSENEVPIYGLKSNGNKACYLANYDELSAFAVVSSNDSVVLINANNRAKVVNVSEITKVSKANKGVALFAKSRTNSPIKQCDSLQASSKILIVNNQGQA---HFEKIQDYAKAAY-AKFINFDVDDTVSLISNYSSDSENSNTHSYDKESAVEEQI.. 830
54 0.000e+00UniRef50_A0A257SGY4 DNA gyrase subunit A (Fragment) n=7 Tax=Bacteria TaxID=2 RepID=A0A257SGY4_9DELT  ali  50  2.............DLFHKQAQPRAIQDEMRQSYLDYAMSVIVGRALPDVRDGLKPVQRRILFAMHELGNEYGKPYKKSARIVGDVIGKYHPHGDNAVYDALVRMVQEFSLRYPLIDGQGNFGSVDGDSAAAMRYTEVRMAKVTGELLSDLDKETVETLPNYDGSLQEPRVLPSRVPNLLVNGSAGIAVGMATSIPPHNLGEVIGALLALIGNPEITIDELMEHVPAPDFPTGGILYGLDGVRDAYRTGRGSVQIRARAFIEKKGDRESIVVTEIPYQVNKSRLIERMAELVRNKEIEEISDLRDESDRDGMRVVVELKKDAVAEVVLNNLYKQTQMQTSFGVQLLAIVQNRPRTMNLKELLEEFLAFRKEVVTRRTLFLLRKAEAREHILLGLSIALDHLDAVIRLIRASKDPKEAKEGLVAKFGLSEIQAQAILDMRLQRLTGLEXXXXXXXXXXXXXXXXXXXXXLGEESELLRVIGQEFREIRD................................................................................................................................................................................................................................................................................................................................................................ 477
55 0.000e+00UniRef50_A0A1U7CIN5 DNA topoisomerase (ATP-hydrolyzing) n=3 Tax=Isosphaeraceae TaxID=1763524 RepID=A0A1U7CIN5_9BACT  ali  29  1MAKRNRNQDRETRARRSSLTEDVPLAEATRSRYLNYALSVITSRALPDVRDGLKPVQRRILYAMWDLHISSDGRFMKCAAVVGEVMKTYHPHGDQSIYDALVRMAQPFSLRQPLIEGYGNFGSIDGDPPAAFRYTECRLTPISETLLSELREQTVTLRPNYSAQAFEPEVLPAQFPNLLVNGASGIAVGMATNIPPHNLKEVCNALLVLLDNREAPLEKLTKHVIGPDFPTGGVILNTAELHKIYATGQGSIKLRGTYEPHPDR-PNSIVVSSIPYGIEKDALVGRIGELIGKGTVPQLINVKDLSTDD-VRIVLDLKPGSNAEAALAYLFKNTPLQVNYGVNLTCLLPAEPARLDLKSILQHFLDFRMEVVTRRLQYELRNLLDRIHILEGFAIVFNNLDEAIRIIRDSDGKADAAPKLIARFDLSPIQADAVLETKLYRLGKLEINDILAELAAKRTRAAELQKLLDDEPARWAIIRDELKQISKTYGDPRRTRIEAPSPMEFREEDYIVDEDSWVIVTREGW---------TKRQRSFTDVASIRVRDDDQVGWIYRARARQTITFFTDRGVAYTLRVNDIPLTTGHGDPIQ-KQFAFEDQEHIVGVVCHDPRCLPDYTKHVQTPARLVQRTLDADGDDAPADRNGHAAVNGDALANGPALPPPPYVVVLTAGGKVLRFALGSLAAISRKGRLVRLDPSFEDDLVVRVEATDGSENVCLATKAARVLIFPITEANVVAGPARGVAAIKLDSK-DRVIGFVLANKKEGLAVRTNRGATQIVRATKYPVTGRGGRGYAI--LQRG----SLECVLPEEAEPIPPVDQVGEGAEG.... 830
56 0.000e+00UniRef50_Q3ERR2 DNA topoisomerase (ATP-hydrolyzing) n=7 Tax=cellular organisms TaxID=131567 RepID=Q3ERR2_BACTI  ali  55  2..........MSDNQQQARIREINISHEMRTSFLDYAMSVIVSRALPDVRDGLKPVHRRVLYAMNDLGITADKAYKKSARIVGEVIGKYHPHGDSAVYETMVRMAQDFSQRYMLVDGHGNFGSVDGDSAAAMRYTEARMSKISMELIRDISKNTIDYQDNYDGSEREPIVLPARFPNLLVNGTTGIAVGMATNIPPHQLGEVIDGVLALSHNPDITIAELMEYIPGPDFPTSGLILGRSGIRRAYETGRGSIMLRAKVEIEEKNGKQSIIVTELPYQVNKARLIEKIAELVRDKKIEGITDLRDESDRNGMRIVMEVRRDANANVLLNNLYKHTALQTSFGINMLSLVNGEPQVLNLKQNLYHYLEHQKVVIRRRTAYELEKAEARAHILEGLRIALDHLDEVITLIRSSKTADIAKQGLMERFGLSEKQAQAILDMRLQRLTGLEREKIEQNIK................................................................................................................................................................................................................................................................................................................................................................................................ 447
57 0.000e+00UniRef50_A0A2V8DZN0 DNA topoisomerase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8DZN0_9BACT  ali  34  40.................GTTEPVALHEAAQSRYLNYALSVITARALPDVRDGLKPVQRRILYTMWQQNLTADVKHRKCAKVVGDVMGSFHPHGDAALYETLVRMAQSFSLRYPLVDGSGNFGSLDGDSAAAMRYTECRLARIADEMLSEIERTTVPFRPNYDGTKTEPVVLPARIPNLLVNGATGIAVGMATNIPPHNLAEICTALIKLLDNEDLSSAQLCRWVKGPDFPTGGQILNPDELKSIYKTGSGSVRLRGTWDLGETRSTKTIYVDSVPYTVNKAQLVERIADIVISRKLPQLVDVKDLSTED-VRIALEMKKDADEKMIMSYLFKHTPLQINFAVNLTCLIPGRPERLDLKSILWHFLHFRLEVVTRRLEHELAALKKRIHILDGFETVFDALDEIIKTIRKSDGKADAAEKIMKRFSLDADQSDAILELKIYRLARLEILIIRSELEEKRKRARQIGALLKDEDSRWKMVRSELEEIHHIHGDPRRTAIEDTSEPEYSADDFIVDEDNVVIVSRDGWVKRQKEVKDIASTRLREG---------DSVLAVLPGSTRATCVFFTNFGVAYTSRIIDVPASTGYGEP--IQRFFKLKDGEKVVAALSLDPRPLVHAVAVSSDGFSLRFGLEPLVEPTRTGRRYARPAKDAEVVGVAKVTGEEVLIVATAQGRGLLCRAGEVNYLSGPGKGVILIKLSADDRVLGFIASTGDRDLLTVTTRGAEQTISTAKYEVTGRGGKGRELLQ........................................................................................ 808
58 0.000e+00UniRef50_A0A0A1ZB60 DNA topoisomerase (ATP-hydrolyzing) n=4 Tax=Prochlorococcus TaxID=1218 RepID=A0A0A1ZB60_PROMR  ali  34  1..............MDKKKFTSISLQEEMQRSYLEYAMSVIVGRALPDARDGLKPVQRRILFAMYELGLTPDRPFRKCARVVGDVLGKYHPHGDQAVYDALVRLVQSFSTKYPTLDGHGNFGSVDNDPPAAMRYTETRLAPIAHKFLEEIGSETVNFSNNFDGSQKEPDVLPAQLPFLLLNGSSGIAVGMATNIPPHNLGEIVDGLIALIENKEISDKQLSKIIKGPDFPTGGELICGNALQELYKTGKGSITIRGVIKIEEKHKKNALIITELPYQINKAGWIEKLAELVNSNKINGISDIRDESDRDGMRIVIELKKDSNAELVISNLYKKTTLQTNFGAIFLALINGKPIQLNLKQYLNYFLEFREETIRKRTNYYLKNTLEKLEILEGLSKATKDIKKVIETIEESENSAEAKSKLIEKFYLSEKQASSVLDMPLKKLTNLEKNQIDDDLEKLQEKKDYFQKLLNERELLLKLLIEELLILKKKYDVKRKTKLLKNIDQNEELETINNQEDFVNKKTKLYIDNRLYLKKMILNNYKKSFEEVNKIIDNKNIKFIFKIEKNIKLIGITLTGKVFHIDW----ESNINNDFKLDNKIIGNINQNEILNFHSMKKGIKNYLCILNSDGRFKKVLFDENMFKSNRSFAITKLKNNIQIIDSFISSEENNLIILTSIGRLFKFNLKNLNPTTKQSQGLMLAKPLPTERIVSCCQYKNGDNIYLISKQGKIFCINSNEIYYANEYNLGYLNERTQLKNDYFLKVSP--SNHYLDIETNKNKSARLDFDKLNFTSNKTN--FLINLEKGEYLENCFRLEN...................... 810
59 0.000e+00UniRef50_UPI000784E81C DNA topoisomerase 4 subunit A n=1 Tax=Levilinea saccharolytica TaxID=229921 RepID=UPI000784E81C  ali  32  1MATPATEINGET------TIQEQPLDHFIEEAYRRYAVLTILDRALPDVRDGLKPVQRRILYAMGDMNLKSSTPHKKSARVVGEVLGKYHPHGDQSVYDAMVRMAQDFSMRQPLIDGQGNYGSIDGDSAAAMRYTEARLAALGESMLEDLEKDTVNWRANFDGSLKEPIVLPARFPNLLVNGASGIAVGMSTNILPHNLGEVCDAVLHVAKNWKKSVEELMKLIPGPDLPTGGLLYRYDMIARAYETGNATLVCQAKADIQDIGGGKSILITELPYQVQKSTILERIA--ASRDKFGGITDVRDESDYNGMRVVFEVARGADPHDVLEKLLTHTQMRSSLSYNALALVKASPHNLTLRDMLVEFIKHRLEVITRRSQYELDRAEARLHILTGLLKALSMIDEVIDIIRRSQTTESAKANLMKKLALSEIQAQAILDMPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXLGSEERRLEVVGQETSDVQARFATPRRTVIEEGHQARVTVSDLVTPTETQRVMVTANGVQRANAKGYRESVTKNKPSSRAVEAALLKVEVA----PDERLVMISSFGRLWQANTGRLPLQASFSE-------IGLERGERIVGM--GAARAGHKLVLLTLSGSIKRVAVEDLPNGRTEGSWIIGLAKDDEVLFAGIASDSAHIVVLTTPPRALRFETGSVNPQATTARGVAAIKVLDDP-LVGAVLIEPNQFVYLLSERGHLKRVSLEEFPVQGRGGQGVQVWKTNPTTGMLTALAVGKADVDLDILSEKGKRLRISAKDVPQATRVTKG.......................................... 808
60 0.000e+00UniRef50_A0A2D5QPV4 DNA topoisomerase (ATP-hydrolyzing) n=9 Tax=Bacteria TaxID=2 RepID=A0A2D5QPV4_9DELT  ali  34  4.SKGSSKTVEPETTSSFEDIEAVKLHEVAQSRYLNYALSVITSRALPDVRDGLKPVQRRILYAMYDLKLRSDSRFLKSARVVGDVMGKYHPHGDSSIYEAMVRMSQPFSLRYPLVDGYGNFGSLDGDSAAAMRYTEARLGGMAERLLSELNQETIDRRANYDGQLEEPAVLPAQVPNLLINGATGIAVGMATHIPPHNLREVVKALLRLIKNPELSTADLTTSVLGPDFPTGGEILNTDEIAKIYQKGQGAIKVRGTYELEKVERTHQIVITSIPYEVQKGNLVEKIAQLVLDKRVPQIVDVRDESTDE-VRIVLELKRGESAEVAMAYLYRHTPLQQNFNINLTCLVPCQPERLGLKAVLRYFLDFRLEVTQRRLQHELRNLKKQIHRLEAFEKIYGSLDEAIALIRESDGRADAEAKLMKRFELDQEQASAILEMRLYRLAKLEIAHVQAELTKKRKRAAECEALLADEPALWDIVKDELKEVRSKYGDERRTSIVPQKETDFSAEAYILKEQTWLIVTRYGRVKRQ---------RGFSDISSIRVPEGDEVGWAIYTDTRKTATVYTQAGSAYTTYVGEIPATTGYGDP--LQSIFKFDDGEKVVGVVVNDDNLPPYGIALTRLGRAHRFPLASFAEVSQKGRRYMSLDAKDDIIHCFASNGDDSVALASRFGRGMIFSIYDIPLRQKSSKGCIAIRLIQGDVVLSFVLTNNPMQGLVVTTTGGREKNSTSKLKKTRRGGRGYEMIK........................................................................................ 801
61 0.000e+00UniRef50_A0A0G8AVV5 DNA topoisomerase (ATP-hydrolyzing) n=7 Tax=cellular organisms TaxID=131567 RepID=A0A0G8AVV5_9SYNE  ali  32  1..............MVSDRIFPTSLREEMERSYLEYAMSVIVGRALPDVRDGLKPVQRRILYAMHELGLTPERPFRKCARVVGDVLGKYHPHGETAVYDALVRQVQTFTSRYPLLQGHGNFGSVDDDPAAAMRYTETRLAPLSHALLGELAEATVDFTPNFDGSQQEPAVLPAQLPILLLNGCTGIAVGMATNIPPHNLGEVVDGLVALLRNPQLSDEALLQLIPGPDFPTGGEIPVGTGLREVYMQGRGSIPLRGVAHLEAVHRRHAVVVTELPYQLSKANWIEKLADQVNDGRVSGIADIRDESDREGMRVVIELRRDGEPDVVLQELFRRTALQSNFGAILLALVDGKPTQLSLRRTLEIFLEFREQTTLRRYRFALGKIGQRLEVVKGLLEALAQLQHVILLISQASEAARAAAVLQVQLGLSPIQAEAVLAMPLRRLTGLERQSLDTERQQLEAEQARLQVLLDDRNSRVKALIRQLQHLRKCYATPRRTRLLGQVVPGAPSRSTEPARSGQQPSARDGQLLVQADGQLRAVSRLNLEQPAPLASQPQPPRCLVPVQPEPRLVVFSAMGRIANLR-WERVAPQPQALARFLPEKLGGQVDRPVQLALLGGSSTAAGVALLSCDGRCRVTELAARAQNSGRTVILFKLRPGRTLCRAAPCPESAVLVVATSCGRLLRLDVTPDLLQELDSAGASLLRLLPRETIVGAACCGDNSQLLLATRHGRLKRLPVEQLAPNRRGDLGQIGLRFLERSDSLLGLWPVADHPCFTLLTTDHRSCRLPWEQAPVQECSGAGESL--LPAGVELTDVIILAETAQLP................. 830
62 0.000e+00UniRef50_A0A0G1X0L5 DNA topoisomerase (ATP-hydrolyzing) n=2 Tax=Microgenomates group TaxID=1794810 RepID=A0A0G1X0L5_9BACT  ali  49  1..............MNIGKVQPSEIVAEMQKSYLDYAMSVIVARALPDVRDGLKPVHRRILFAMHQIGLHHTSKYKKSASVVGEVLGKYHPHGDAPVYEAMVRLAQTFSMRYCLVDGQGNYGSIDGDPPAAMRYTECRLAAISDEMLLDIEKETVEFTPNFDGTIDEPNYLPAKLPNLLLMGSEGIAVGMATKIPPHNIKEVIDAIIFLIFHFDVTVDELMEYITGPDFPTGGAIYDINEIKSAYATGRGKIVMRGKAEIEDIGGKSAIIITELPYQVNKAQLVMKIADLVKEKKIEGISDLRDESDRRGIRVWVELKRDARPKQVLNNLFKHTALQTTFPVNMVALVDNTPQTCGLKLILEEYVKHRHDVIRRRSEFELRQAKAREHILEGLKIAVDHIDEVISIIKKSKDADEAKAKLMSRFGLSDIQTTAILDMQLRRLAALERQKIEDELAMIQETIAYLQDLLAHPEKILKVVKQELTKLKEKYGDERRTRVFKSKVGEFSEEQLIANEDVIITMST............................................................................................................................................................................................................................................................................................................................. 534
63 0.000e+00UniRef50_A0A2N2M1V2 DNA topoisomerase (ATP-hydrolyzing) n=6 Tax=Chloroflexi TaxID=200795 RepID=A0A2N2M1V2_9CHLR  ali  32  19MTDRNEENEEIL-------VHEHALDRFIEEAYRRYAILTILDRALPDVRDGLKPGQRRILYAMGDMNLRHDTPHKKSARVVGEVLGKYHPHGDTSVYDAMVRMAQDFSMRAPLVDGQGNFGSIDGDSAAAMRYTEARLSSLGEIMLADIDKETVNWLPNFDGSLVEPDVLPTRFPNLIVNGATGIAVGMSTSILPHNLGEVCDAVKFVTQNWKRTVKELMKYIPGPDLPTGGLLYRYDMIAQAYETGHSTMVCQAKADIQDIGGGKSIIITELPYQTQKSTILERIASARE--KFVGITDVRDESDYLGMRVVFEVGRGVDPVDALDRLLINTQMRSSLSHNALALVNDEPKNLSLLDMIVEFIRHRLNVITRRSRFELDKAEERNHILEGLLKALSMIDEVVSIIRKSQTTETARKNLMEKLDLTGVQAQAILDMPLRRLASLERKKMEDERKDLMQNIKFLKTILSSQDRRLEVVSQETEEIKDKYAQPRKTVIVESEEGHVTVSDLVTPTEDQLIMIQSAGLQRVDAKSFHENVTRDK----PTSRAVSIALLRETAKPEENVLLISNQGRLWQGNAGRLPLAGSFED-------LGLKHAEKVVGLGVVRE--KQKLVIVTTAGQIKRVEMADILSTRAEATWAIGLNANEEVLYAGVSSDDAHLMICSAGNRVLRFETNSINPQATSAKGVTAIKMLGDP-LVGCVLVEPGTNVVAVTLKGHLKCISIDEFPIQGRGGQGVQLWKITPDTGPVAGITVGTEKDQVDVFSEKMKRIRLDVKSLPKVTRATKGVKGDLFGAGEFVAGVVV......................... 850
64 0.000e+00UniRef50_R5V532 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Firmicutes bacterium CAG:631 TaxID=1262996 RepID=R5V532_9FIRM  ali  34  1MATRKTKVDDEFVTNTDTSMIYGPFEDIISERFGAYSKYIIQDRALPDIRDGLKPVQRRILFGMKELGIVANTPYKKSARIVGDVMGKYHPHGDSSIYDAMVRMSQWWKSNEVLIDMHGNNGSLDNDPAAAMRYTEARLSSVAMELLKDIDEDTVEFTFNFDDTLKEPTVLPTRFPALLINGAKGIAAGFATDIPPHNLSEVIDGTIHRIKNPNCRLETMMELIKGPDFPTGGIVFGKKGIIDAFTTGKGKIVVRGKAEVIEEKNNRKIVITEIPYDIIKIALVKRIDEIRFNKEIWGMVEVRDESDRNGLKIVIDITNEADAQLILNYLYKESDLQTSYSYNMVAIDHKTPKQVGLLAVLDAYIEFKKEVILRKSQYNFDKKTARLHIIDGLIKAISIVDELIDTIKKSKNKADAKENIIAKYGFSEKQAEAILMLQLYRLSSTDXXXXXXXXXXXXXXXXXXXXXLTQESALKNVMIAELKEIKSKYGHPRKTVLKDIEEIVIDKVSTVIKEDVMVAISRDGYAKRSQLKSYNSSNSTFPGYK-----QTDAIVAISQASTLDTLLVFTSGGNFMYLPVYELVENKWKDEGVHINKIASFPSNEKIINAFVVKEFRDDYITLASSKGSIKRTALSEFVLQRSKAVSCFRLQEGENLVAAFLTNGGCDIVVLYKNGALVRYDENQVGIVGLKAGGVRSGSRALDCDLVGGIALDEEKNMMIVTDKGGLKPVYPRYINQTNRTTVGTLSFKFRSDHHDAVGIITYNEGDILQVVTNF-KSMDVLVDDVPYQPID----KIIKLEKREKVEAITI......................... 814
65 0.000e+00UniRef50_Q8G4F2 DNA topoisomerase (ATP-hydrolyzing) n=331 Tax=Bacteria TaxID=2 RepID=Q8G4F2_BIFLO  ali  35  1MASRKPSAQTYDPRTVKEHIVETPLNEEMSKSFLEYAYSVIYARALPDARDGLKPVQRRIVYQMGEMNLTPDRPYMKSARVVGEVMGKLHPHGDSAIYEAMVRLAQPFAMRLPLVDGHGNFGSLD-DGPAASRYTEARLGPAALGMNADIDEDTVDFTPNYDNKLKEPTVLPAAIPNLLVNGGSGIAVGMATNLATHNLGEVVNAAKFLMAHSDATLEQLMRYVPGPDWPTGGTIIGRDGIREAYATGRGTLTTRAATHIEHVTRKQAIVVTELPYMVGPEKVIERISDGVKNRKLEGISGAFDLTDRHGTRIVIEIKTGFDPHAVLVQLFKHTPLQDNFAMNNVALVEGRPHTMGLKEMLQVWVDHRRVVIRRRSEYRKKKALERLHLVEGLLLAMLDIDEVIQVIRTSDDADAAKSRLMVVFDLDEVQAQYILDLRLRRLTKMNXXXXXXXXXXXXXXXXXXXXXXXXXXXXDQVVTDEMDEAVAKWGSPRRTVLLDADPDTLTGALKIEDEPCVVMMSATGLIARTTPSAMDVFNARS---TSDERLRDDQITTIFETSTRATYGLVTSAGRLVLAHVVDLPAGVQADELIGMTESTDPIRGERVITAIAMEQPTSPSLAIGTRNGVIKRWNRE--APTTMDSWPVIDLKDGDEVVFAAVAEDDDRLVFISSDSSLLTFEAKNVRPQGRTAGGMAGIKLAEGARVAAFNVVPAGKVVLTVTENGAAKVTPLEMYPTKGRATGGVRSQRFLKGQNTLILAWV--GLYPLHASTSAGSPVELPK---PDMRRDGSGV......................................... 899
66 0.000e+00UniRef50_A0A2G4RED4 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Acetobacter pomorum TaxID=65959 RepID=A0A2G4RED4_9PROT  ali  34  37....EDSLADEVVGKAIGDVREIPMAETMSESYLNYALSVIMSRALPDVRDGLKPVHRRVVYGAS----AHSKGMVKSARIVGDVMGKYHPHGDVSIYESLVRMARSWTMRFPLILGQGNFGSRDGDSPAAMRYTEAQLRKQASALMKDVELDTVDFNPNYDGSEIEPSVLPARIPLLLINGVEGIAVGFASSIPPHNPEEVVKATIEVIRNPDVTGSELRQIMPGPDFPTGAISVDNGGYAKAFDTGKGSVHMVGTYEIKKKAGRQQVIITSLPYEVNKAKLVAHINELKNAKGFNDIAEVRDESAKEDIRIVLDLKKGANTDLIIKNLSSRTAFATSFNYNMVVRTPGKPQLLGVRQIIDAFIDFRREVLWRRTNCLLEKERKRLRTLTGLFAARTQIRDVVKIIQDSEDSPSAKLALQEMNFPVEEQAQSILDMRLSNLTKLQLNEISEEAIKLREAMQSNLHLLADKSAMDELMIAEMEEFMVGYGPCPRLTTIERGVDEVEDYQLLPNIPVVLSVTQRAYVKITEVNEFQEQARGGTGRKGPVPRDEDYVAHAMPCMTHDMITFFTSLGMAYAVRAEKFPMGNKSPGRPIINYGVELKEGEKITAVIKMPEAEQKFLMFVTEDGNVRRNRMSDFMNINRGGKIAMKLEEGGEILAVLTCEADEDLILASSSGRAARLQINDVRIASRNSVGSRGIKLGPNERCVSACIVPHEKTLITVSEKGIGKRFSSYEVRTVARGGKGVNIGTFTLATGGLAGLLSVDDGDGLLLVTNKGMAVRTGCGGIAKTSRTSKGVKLLKIKPGDSVASVCVLKPTTEDEFVDNDLEEQDEDD.... 957
67 0.000e+00UniRef50_A0A066RK62 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Photobacterium galatheae TaxID=1654360 RepID=A0A066RK62_9GAMM  ali  30  1..........MTINYTHQNFGEIDLGAHAEAAFCEYSKYVTQDRALPDIRDGLKPVHRRILFSMYELNNTFNKPYKKSARIIGDVLGKYHPHGDSACYGSLVRMTQPWVMSAPLADGQGNWGDTDKNSAAAMRYTEVRLSRVSNGLMDDLKTETVSWKPNYDGSEKEPEVLPARFPNLVINGVEGIGIGMASSIPPHHPVEAMNCVLALLEGRKSPTEKLMALMPAPDFPTGGVVYALENYQQVWELGQGSVRIRAEWEEELIEGRKCIVIKSLPYGVSPSDALIQVNQARRPHPLRGITGERDEGDSDGLRLVFEVNYGVEPEIALNELCNNSCFDISVSYNMNVIDQMEPVSIGLRQAFDRFIDFREDVVTKRSTKLLSDAKSRMHILDGFIKALDKMDQTIAMIRNNPKQSDAKAALIEFLEIDALQASKILEMTLGKLTQGEVSNYKREHEKCALEVADLEDILRNRSRLLDVIREETEAQQGAKLYEMRRSQWTHEEMRLSKADQIPREYCSVILSQQGFTRRISAEELKEQRRGTQGTQQIELAKRDSIALATECFSHDVLAFVTSLGRIAFAKAYEIDTSLRGQHIHNLVKLDTAQDEKVIQIVSIEDEMVEHQLVLATKRGMIKRTNFSLFNPKVSRTVKAIRLSEGDEVAFFGVNRESDVITLASSGNKVVRFTLSEIRETSRTSRGVMAMNLDCDAHIVSCSVVKAEALIGFVSKSGQLKITQLAHYRQTKRKAKGVTAMKLAEK-DQILSAFTLDESEDVVSTSKKGKMNRVNLGSFRVMNRMTQGVKFVSMKDKDELISAYLVRGEKENPVDEIDEAIAPDSGQVT. 861
68 0.000e+00UniRef50_V9RB96 DNA topoisomerase (ATP-hydrolyzing) n=4 Tax=cellular organisms TaxID=131567 RepID=V9RB96_9MOLU  ali  37  3.AKPSSNLEKLLGALANSQVHERNLVKEAEQSFLDYSLSVITSRALPDLKDGLKPVHRRILYSAYEEKMFNDSRFRKSATLVGSVMGGYHPHGDSSIYMALVRMAQDFSMRYPLLEGQGNFGSIDGDAPAAMRYTEVKMSKLGEKFLDGIKEDAVDFVPNYDGSKEEPVILPIVAPSILLNGGEGIAVGMASKIPPHNLQEVCELAIALLDDTSLPVEKMFEIMKGPDFPTGGLVLGYKGIQKYLLTGKGSFRIRARAQLDWEKN--QIIFTEIPFGVKKSSIIKKIARLASDEKNPFIRNIRDESNKEGIRLVIECGKEAPLDTILNNLYKYTSLQHSFSSNITLLSKGEPKTLGIIPILREYLEYQLEILVRRTQFNLEKLRARIHLLEGRKTIVTDLKTAIDIITQEDEPE---KLIKDKYSLSDIQVKDIFDLPIRQLKRIEFQKLIDELEEKVGFRIAHEERLASKELQHQEIKKQLMDIMQEYDDPRRTDIDQTKGYSLSQLDLIPKETLVINVSEKNYISALPLKGIKLSNRGTKGFDLSNDQSRDFVSDLLIASSHDDIFLFTNFGKVYKVKGYDIKVSNSNKKNILGYKDSPFKEGEKVIAITPEDYEKDLYLLFATKQGRVKKTRLSDFKTITKKGKQAFKYNEDDELMGVIKITDESEIFLTSPDARVTRFNAKDIKPRSRGSGGQKGINKTYVGDLVSVSSSYEGDKLLMISETGKGKINEFNVFESKRKPKRGMVAYSVKSKTGKLVACVAVWGNEEIALMTKKNHLNRFNVSKIPTLGGNTVGVKLIDLKEDDKVIKFAKVSLNDDLKELKQENTNSVEE..... 906
69 0.000e+00UniRef50_R7MHU7 DNA topoisomerase 4 subunit A n=27 Tax=root TaxID=1 RepID=R7MHU7_9CLOT  ali  31  1MAKKK------IEENIVEKIYDYTLEEIMEDRFGRYAKSIIQDRALPDVRDGLKPVQRRILWSMYESHNTYDKPFRKSAKAVGDIMGHYHPHGDSSIYDALVRLSQRWKMREPLVEIHGNNGSIDGDGPAASRYTEARLSKIANVMLSDINKDAVKMTLNYSDEDLEPTVLPAHFPALLVNGSTGISAGYATNIPPHNLTEVIDATIKRIDSPNCRLDTILEIIKGPDFPTGGVVEGKEGLIQAYTTGKGKVVLKANYEIIEEKGKKQILIKEIPYEVLKEQLKKKIEDIKSDKKIDGIVDVIDESDRTNMRLVIELKKDADANLIINYLLKNTDLQINYNFNVVAIDNKRPKTLGLLEILDAFILHKEEVVINRSKFDLEHSKKRLHIVEGFIKALDILDEVIKTIRKSKNKADAIENLVKEYDFTTEQATAIVMMQLYKLTNTDVTDLQNEHANLLELIKYLTSVINDESVLKGVMKDELRSIKKEFATPRRTIIKDITEIKIDELSMIPKEDFIVSVSKSGYIKKLSIKVYNSNN-----ETEYVLKEKDYLIGLYKINNIDTIILITNLGNYCYLPVRDITECKYKDIGKHISSYIPLSEGETIIASFGIKNFDSRTITLFSKDGFVKQTELSNLVTRYSKPMTIFKLKDNDEVVSASI--NDGVVYIVTENGFALKFNKEEIPVVGLKTSGVKGIKLVSDSVVSAFVTNENHEYITIFTDKNTAKRIKLEEIDYSKRSLKGNILHSPKSKKYKITECYAGSSKTNYGLIREDTETI--KSSEINIMDKSSTGSTISKKDLTDKVIDDVKLENSEVSNEEKDNSNESVKEEKVSK 835
70 0.000e+00UniRef50_A0A1V6IJZ1 DNA topoisomerase (ATP-hydrolyzing) n=2 Tax=unclassified Tenericutes TaxID=713063 RepID=A0A1V6IJZ1_9BACT  ali  33  1MSKRKPKKQTE-EQVITETIIELPMDEIMGDRFGNYSKYVIQNRAIPDARDGLKPVQRRIIYAMHDEGNTFNKPMKKCAHTVGAVMGKYHPHGDTSIYDALARMSQEWSMRYPLIDFQGNNGSIDGDEPAAYRYTESRLNELSNELVLDINKKTVNMNLTFDDTSFEPEVLPSRFPNLLVNGSQGIAVGVATEIPPHNLREVVDAIIHRITYKRSTIEDMRKYILGPDFPTGGVIYKGEGLDSIYETGRGRVEMEALATIESDRTSQRIVITEVPYQSNKSQILRELGAIEQNRNVDGVVEVRDESDRNGIRIVIELKKEANTDVILEYIFSKTRLRAGYNANIVAIADNRPKTLNILDLIDAYISHQVDVITRRSEFDLATNEKRLHIIEGLIKAISVVNEIIAIIRKSTDKANAKTNIKAAYGFSEEQAEAIVMLQLYKLSNTDITVLMEEKAAIETTIDELRNILSNEKALNNVIIRDLKRIAQKFGDDRRTKIREKGEVQIDKRDLIADEQVMLALTRDGYIKRSSLKSYRSSG----DFALPGVKSSDLLIAASEVNTKDFLVAFTNLGNYLYIPIYEIGEGRWKDEGKHINYIVQLNANEKIIKAFNVKEFREDYFAIATRNGMIKRTSLNEFVAVRSRPLQAMRLLSGDRVADVTLTTGNSELLVITESGAASFYNENEITVVSVKASGVKSINKKKADKVVALISVDPETRTCIVTSEGHLRLLDHSYFEATARLGRLQHVMRTFKDPHTIVSAFRYNRNIEVYALTDANVILPLLLTDLAPTDKYAK--RNINLAEEEKIVSIF----NEEIPTISEETK.......... 830
71 0.000e+00UniRef50_A0A1Z9JEG1 DNA topoisomerase (ATP-hydrolyzing) (Fragment) n=11 Tax=cellular organisms TaxID=131567 RepID=A0A1Z9JEG1_9CYAN  ali  46  1MADSVGPGGGGPGDSD-DRIIQADLRNEMSRSYLEYAMSVIVGRALPDARDGLKPVHRRILYAMYELGLTSDRPYRKCARVVGEVLGKYHPHGDTAVYDALVRMAQDFSMSMPLIDGHGNFGSVDNDPPAAMRYTESRLQSLTTDLLEDIEAETVDFADNFDGSQQEPTVLPARIPQLLLNGSAGIAVGMATNIPPHNLNELISGLLALIENPEXSEQELIRLIPGPDFPTGGQILGRDGIRETYLGGRGSITMRGVAAIETIEDRDAVIITELPYQTNKAALIERIAELVNDKKLEGISDIRDESDRDGMRIVVELRRDAYPQVVLNNLFKLTALQSNFSAYMLALVNGEPILLTLRKMLEVFLDFRVETIERRTRYLLRKAEERDHILLGLLLALNQLDPIIALIRAAPDTATARQQLQDRHGLSDIQADAILQMQLRRLTALEADKIRLEHEDLVTKIADYKDILGRRERVFGIIQDELNQLSDRYTTPRRTEILD-LGGGLEDIDLIANERSVVLVTETGYLKRMPVSEFEATSRGTRGKAGTRSQGEEAVKLFISCNDHDTLL............................................................................................................................................................................................................................................................................... 572
72 0.000e+00UniRef50_A0A2A5E534 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2A5E534_9BACT  ali  33  15...KEENQPEEDIGDDIGFIKTLDFSKGMSDQFLIYANEVIGYRAIPDIRDGLKPVHRRILYGMYVNDYKASDKPKKSAQIVGKVMGEYHPHGDASIYSAMVRMAQPFSMNIKYIEGSGNWGNRDGLSAAAMRYTECRMTNFSEEFFEAIKKDVVPFGGTYDGMHKEPLVLPIVIPTLLVNSLSGIAVGLATDILPHNLGEVVDCMIRYLDNQDISDDDLIG-NLTPDFPTGCLAYDKENMMKIYKTGQGRVRVRGVYHVEDEKK---IIFTEIPFQLSKKNLIEEIANHCDNKSIEGINDVWDESTGD-VRLVIEINNRTNAEVVVAQLFKYTSLETTFKANFTVLINGVPTVVSIRRIMEEFVKFRIKCIKNELQFDLNQAEATLHIREGLKIVHDHLDRVIEIIRGSSGDEESRKKLMDEFKLSEKQADSILAMRLGNISKLQGRKVQDEINELQTKISDLKSFLADSARINQKIKDMALAIKDKYNIPRRTKMVGGFSDT-DILDLIVEEEIVLLFTSDDKIKANRISDYKTQKRGGQGSFGANTQDGVFTKFIVRSNTRETLLIFTNKGNCFWLMAYKIPLTNKQNKPLNVHGLLNPEEGESVIACLSINEFDDKNIMILSKAGLIKRLKLPWFERFRKRAYKIYPCKDNIDVLSVKMAHSEADLMMFTKNGNALRFNISKIRESNRSAMGVRTMKLKGDDELLGFSTVQDDQFVMNITEKGYGKLTPAKEFSVKGRTGSGVVYCKISEDTGKCVLALPVYLSGDILVMTSNSKTVRVKVESIRICGRSARGVIIQKMMKGERVVAGAFIAEEDEIRETQQSLDETHASIEIP. 859
73 0.000e+00UniRef50_A0A2A1ZST1 DNA topoisomerase (ATP-hydrolyzing) n=3 Tax=Tenericutes TaxID=544448 RepID=A0A2A1ZST1_9BACT  ali  35  1MARKK---VLEQIDSYVEKIITENLEDIVGERFGRYSKYIIQDRALPDVRDGLKPVQRRILFSMYKLGMFSDKPYKKSARIVGDVIGKYHPHGDTSVYDAMVRLSQPWKVRCLLIDMHGNNGSIDGDSAAAMRYTEARMSKISEYLLKDIDKRTVDFVPNFDDEEYEPTVLPARYPNLLVNGATGISAGYATEIPPHNLREVIKAVILKIDDPTTSMDQILKVVKGPDFPTGGIVQGKDEIRKAFETGRGKILIRSKLEIID----HSIIVTELPYEVNKANLVRKIDDIRISKQIEGIQEVRDESDREGLRIAIDIKKEANPELILNFLLKKTDLQRNYNYNMVAINNKRPVLMGILEIIDAYILHQKEVTTNRSNFELTKAQKRLHIVDGIIKMMDVLDEVIHIIRSSSNKRDAKDRLMEAYSFSEEQAEAIVTLQLYRLSSTDXXXXXXXXXXXXXXXXXXXXXLHNEGALQKVIKDELEDFLKSFKAPRLTIEEEIEKITINEEDLITEEQVMVGVTKEGYIKRSSIRSYRATND-------ANLKEFDTFMVEKELSTLDTLLIFTNQGNYIFIPVYKVPDYKWKDLGTHINNIVQLDLDERIIKVLDIQDFKEQYLLFATRNNLVKISKLSDFLVSRFSKIKAIGLNKGDSVVSITVTNSEKEVMVATENGLAIRFDLMEIPLTQNTAKGVKAMNIAKNQKLAYAVALEDNNDLLVLTNRGTIKRVNILSIPKKKRANRGTHLYKEVKSNPYLVVALQYKNKVGIKIITSKGE-KIISAFDIK-TDTTENGKSFIKKKEGEFIQ-IEKIELDDTIPPLSEYVKEDEETEVQT. 833
74 0.000e+00UniRef50_S2R6N9 DNA topoisomerase (ATP-hydrolyzing) (Fragment) n=17 Tax=cellular organisms TaxID=131567 RepID=S2R6N9_LACPA  ali  53  2............DDRQESRITNVNLGETMRKSFLEYAMSVIVARALPDVRDGLKPVQRRILYGMNELGVTPDKPYKKSARIVGDVMGKYHPHGDSSIYEGLVRMAQDFSYRYMLVDGHGNFGSVDGDGAAAMRYTEARMSKIAVEMLRDINKDTIDFQDNYDGTEKEPVVLPARFPNLLVNGATGIAVGMTTNIPPHNLSETISALHVLMDNPDATTADLMQALAGPDFPTGGVVMGKSGIRHAYETGRGTIVLRGKVDVQEKSGRERIVITEIPYMVNKAKMVERIADLVHEKKIDGIVTLRDESDRDGMRIVIDVRRDASASVILNNLYKLTPLQTGFSFNMVAIVNGAPKVLSLKQILQYYLDHQENVIRRRTQFDLRKAKAREHILEGLRIALDHIDEIITIIRSSETGDKAKVILMDKFKLSDKQSQAILDMRLVRLTGLEREKVESEYKDVEAAIADYTDILARPERVHQIIYNELLDIQKKFGDKRRTELLVGEVLSLEDEDLIEQEDVVITLSHNGYVKRLATSEFKAQNRGGRGIQGMNVHDDD.............................................................................................................................................................................................................................................................................................. 543
75 0.000e+00UniRef50_A0A1G3X1C5 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Tenericutes bacterium RIFOXYB2_FULL_36_25 TaxID=1802357 RepID=A0A1G3X1C5_9BACT  ali  33  1MAKDVIKQ----VNDYIEKIIESSLEDIVSERFARYSKYIIQDRALPDARDGLKPVQRRILYAMQQLGMLHNKPYKKSARIAGEVMGKYHPHGDSSIYEAMVRLSQDFKMRVPLIDMHGNNGSIDGDSAAAMRYTEARLSKAAEALLGDIDKRTVPFVPNFDDEELEPVVLPAKFPNLLVNGAKGISSGYATNIPPHNLKEVILATLAFIDNEKMTLAEVSEIIHGPDFPTGGIVQGHAGILQALETGSGKIVIRSKSMVEEIKSQDRIIITEIPYEINKADLVKTMDMFRIDKKIEDILEIRDESDQEGLRIAIDLRKGADAQLILNLLFKNTDLQVTYNYNMVTIMNHRPVLVGVLPILKAYIDHQKDVITNRSNYELAKANKRQHIVLGLIKMVSVIEEVVRIIRNSQNKQNAKENIMQAFDFSELQAEAIVTLQLYRLSNTDIIALEQESVGLSERIKELEHILSSEAALRKVIKRELTEMMDLLGEDRKTEIEEISNIKIDQKDLITDEKVMIGITKDGYIK-------RASTRSYQASQSCGLKENDALMFEQELNTLDTLLMFTNMGNYIFLPVFKIDEQKWKDLGIYINNITPIEKNEILMKVMAISHFDDKNILIATKQGMMKQAKLQDFEVTRNKPIRCMRLSDGDEVISVDL-NEKVNILAISMKGYALRFKTEELPLYGLQAGGVKSMSLQDGDEVAGARYVKPGDDFIILTNRGHVIKDVVEELPLYNRNRRGILIIEHQKANPHLASRQQQKENVGVLIITEKG-SLACTVNDLKYTG-NKFGKKIFDLGRGYLITIFDAIDEKDEIRKEKIVKKDVIKP..... 833
76 0.000e+00UniRef50_A0A1U9LJS9 DNA topoisomerase (ATP-hydrolyzing) n=3 Tax=Acetobacter TaxID=434 RepID=A0A1U9LJS9_9PROT  ali  35  13..DIDETLADEVEGKDIGAVNIVPMEDSMSTSYLNYAMSVIASRALPDVRDGLKPVHRRVVY-----GAAPSKGVVKSARIVGDVMGKYHPHGDASIYDSLVRMAQDWTMRLPIILGQGNFGSIDGDSPAAMRYTEAQLQPQAHALMKDIDLDTVDFVPNYDESEQEPSVLPARIPLLLINGVEGIAVGFASSIPPHNPEEAIQATIAVIRDPSISDEALRQIMPGPDFPTGAVCVDNGGYAKAFATGNGSVRLVGTHELKKKAGRQQIILTSIPYMVNKSGLVAKINEMKNTKGEKDIQEIRDESSQKGIRIVLDLKKDANADLILKNLESRTLFSRSVNYNMTVRGPGKPLLLGVRQVMDEFIDFRREVLWRRTNFLLEKERKRLRTLTGLFAARTQIRDVVKIIQDSEDGPSAKLALLEMKFLTEDQAKSILEMRLINLTKLQLNDIEEEAVKIKASMEGNLHLLATPAALDEVMISEMEEFLQGYGSCPRLTELQRGVDEVEDFQLYPNVPVVLSVTHRSYVRITEQDSFREQNRGGKGRKGAVPRDEDFVTHTVPCMTHDMLTFFTSYGKAYAVRAGSFPMTASSSAGRPIVNFIELEEGEQIAAVIKMPEAENKYLMFVTSAGSVRRNKMSDFMNIRSNGKKAMKPDGGDILLAVLPCHEDEDLILASSSGRAVRFNAKNIRVASRDSAGTRGITLGPAERCVSACIVHHSDTLITVSERAIGKRFSSHEVRVSSRGGKGVSIGTFTPATGGLVGLLPSGDTDGLLIVTSGGQAIRTGCKGIRRTARSGRGVILFKVPVGDKIASLCILEAEDEDDLEATEAEGDEASETDDE 941
77 0.000e+00UniRef50_A0A0R2AG14 DNA topoisomerase 4 subunit A n=23 Tax=Bacilli TaxID=91061 RepID=A0A0R2AG14_9LACO  ali  35  1..............MAHNNIQELSLEAVMGERFGRYSKYIIQERALPDIRDGLKPVQRRILFAMNEDGNTFDKPFRKSAKAVGNVMGNFHPHGDSSIYEAMVRLSQNWKLRDPLIEMHGNNGSMDGDPPAAMRYTEARLAEIAGEMLKDIEKDTVEMVLNFDDTEYEPTVLPARFPNLLVNGATGISAGYATEIPTHNLGETVAATIHLLEHPQASLDDLMQFVKGPDFPTGGILQGLDGIKQAYQTGRGRSILRAKTEIEAIGGKEQIVITEIPYEVNKSLLVKRIDELRLLKKVEGLAEVRDESDREGLRIVVELKKNANAQGILNYLFKNTDLQISYNFNMVAINNKRPEHVGLKTILEAYIKHQREVTSKRTQYDLAKAKKRQHIVAGLIKALSILDQVIKTIRASKNKGDAKANLIANFAFSEAQAEAIVSLQLYRLTNTDXXXXXXXXXXXXXXXXXXXXXLASQKELDKVIKKELTALAKKYASPRLTEIAEIETIQVDTEVTVAQEEVMVLVSHDGYVKRSSLRSFNASGDGENGLK-----DEDYPVLQQTANTLDHLLIFTNKGHLIYRPVHEISEERWKDTGEHLSQTVGLGPDEIVKAYIFNTLETEGLFVFATKNGFIKQTPLSDLKPGRTYKSRAMKLKQDDELILIAYGSQNKEVFCVTYGAYGLRYDLSEVPVNGAKAAGVKCMDLRDDY-LTSVILTDEKQAVALVTNRGAFKKMKVSEVAKTTRARRGVQIMRELKRNHRIVLARIITE-DKVQLITDHQEEITISYAAHSFGDRYSNGAYILDID................................... 795
78 0.000e+00UniRef50_P72525 DNA topoisomerase 4 subunit A n=4977 Tax=root TaxID=1 RepID=PARC_STRPN  ali  35  2.................SNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRILYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMHGNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFPNLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAIIQGRDEIKKAYETGKGRVVVRSKTEIEKKGGKEQIVIIEIPYEINKANLVKKIDDVRVNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDNFTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALIRASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLAAIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTKAIEIDTASLIAEEDTYVSVTKAGYIKRTSPRSFAASTLEEIGKR-----DDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELADIRWKDIGEHLSQITNFETNEEILYVEVLDQFDDATTYFATRLGQIKRVERKEFRTYRSKSVKYAKLKDDDQIVAVAPIKL-DDVVLVSQNGYALRFNIEEVPVVGAKAAGVKAMNLKEDDVLQSGFICNTSSFYL-LTQRGSLKRVSIEEILATSRAKRGLQVLRELKKPHRVFLAGAVAEDQTLLVQSNKGTIYESRLQDLNLSERTSNGSFISDTISDEEVFDAYL......................... 815
79 0.000e+00UniRef50_A0A1I1D7V0 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Brevinema andersonii TaxID=34097 RepID=A0A1I1D7V0_9SPIR  ali  34  1..........MSNEFLNDGISPSYFENELETSYLNYAYSVITGRAIPDARDGLKPVHRRILFSMHELGILYDKQTRKCARVVGDVLGKYHPHGDTSVYNAAVRMAQDFSTRYPLIIGQGNFGSIDNDPPAAMRYTEAKLSKVAYYMLNDLEKDTVDFRPNFDDTLEEPMVLPGMFPQLLCNGTEGIAVGFATGIPPHNLKEIVSATSAYLDNEHITLDELMKHIQGPDFPTGGCITNRSNLRNIYETGQGSIRVAGSIHWEEKS--HSLVITEIPYQTIKSRIVAEIVALIADEKNKHIKEVRDESSKTGMRITVELGKTGDANTIKSILYKETRLEINISVNMVSLRENRPELLGLKTLIGSFAEHRRIVVDRRHRFVKRKAEERLHIVNGLLIAQENIDEVIKTIRGSADTKTAKDSLMSQFLLSETQSQAILEMRLQRLTSMEXXXXXXXXXXXXXXXXXXXXXXXXXXXXDALIKKELADMCADIGDGRRTVFGNTDVPQLDNEEFIENKSMHLAISHQGYLFVEIETIGRGSKRTGNATGGRKLGEEDYIIASAACNIKDTILFFTSDGKAYSVKGYEIAGYSNGLQVRHTNSVPRLESIEGDIAAVMFVDRFDDQHYIVFKFGQGVRIPLSLFGNISRSGVIALKLKPGDELMSAVKTTGNDTLLFVKRKGKGFKLDEKLFTPHNRGAMGERAIRVEDEQDVIGMAVDESDKNVLFVSQTGRGRRVNPKDFSLTNRGGKGYKLINLRD-GEFITDFAYVKENESVFIVSKAGQRATLKASDV---TNYASQLLVMKV--DDEITALSVVPPEDLELKESKAMTD......... 829
80 0.000e+00UniRef50_A0A1Q9NGA9 DNA gyrase subunit A n=1 Tax=Candidatus Heimdallarchaeota archaeon LC_2 TaxID=1841597 RepID=A0A1Q9NGA9_9ARCH  ali  36  3..........DSEPIDADSQYETSFTKEMKFGFSNYAKYVISDRAIPDARDGLKPVHRRILWAMNQIGLGPRSPFKKCARIFGEVTGKYHPHAGG-VYESLVRLAQDWSLRYPLVQPQGNFGSIDGLPPAAMRYTEARLNRISLELMENISERVVEFIDNFDGEEREPTVLPVKIPHLLLNGSYGIAVGISSNIPPHHLNELMSACIAIIDDPQISVDDLMTHVTAPDFPTGGTIIGLSGIRSLYLTGRGSMRIRSKIHLETNETHKRLVVTEIPYLQNKATIITQISKLIDDNSLRGVMDVRDLS-KEDIRIEIDIDEDLGVKTILGQLYKKTNLDTLFHSRMTAFVYGRPMTLTLKKALAVFLDFRETTIRNITQEELDKVAARIHILEGLIIASDHIDAVIALIRASESRSAAHTNLKDKYALSDIQAKAVLDMTLARLARVEQTALVDELETKNADKARLMMILHDRPTLLELMRNEFEDIKKKHSDKRRTNLVEMDDVLTSSERPIHRRNLLITSTGEGYLRALDYTKFKTQGRGGRGVIGVPLGTDEKLFDMMIASNMDDLLLITHNGIIHLIPAYEIPEAKRTNKGKTIKRFLPVESIVKVVNIEHDQFVKEKVLVTITKNGVIKRTTLDKYANIRRTGIKCLNLRGEDEVVDAFVTDGNSFIFIASKKGQAVVFDETKARAMGRVAGGVRGMRLRVGDEVVSSFAIPKDQSILTVTERGYGKRTILTKYRFTNRGVRGVINMKIREKNGDVVPMPIVAGSSNISLVNSDGVLIKVRVKGIRNMGRSTMGVRVMRIVGDQKLLMATSIVDENVEILEQAEIDLEDPIDDGEE 847
81 0.000e+00UniRef50_A0A2T2VA03 DNA topoisomerase (ATP-hydrolyzing) n=2 Tax=unclassified Bacteroidetes (miscellaneous) TaxID=37452 RepID=A0A2T2VA03_9BACT  ali  39  422................................................................YDVQVSGPHEFVAGGMVVHNCLGKYHPHGDSAVYDAMVRMAQPWSLRYPLVDGQGNYGSLDGDAAAAMRYTEARMESVTEALLTDLGKETVDFRENFDGTLEEPTVLPAGFPNMLVTGASGIAVGMATKIPPHNLGETIDAVVARIEDPEVTIPDLMKRLPAPDFPTGGVIYGYGGVQDAYKTGRGRVVMRAKMHEEELDGRQALIATELPYQVNKSRMLEKIADLVRQERVEGINGLRDESDREGLRVVIELKQGAVPMVVKNKLFKHSHLQQTFGVNMVALVNGRPQVLDLREAIDVYVEHREDVVRRRTEYELRQAEERAHVLEGLTLALDHLDAVITVIRHSPDTGTARENLMAGTYPSDLTEEDLGELSDAPAEEGAWLSRRQADAILKLRLSRLTGLERDKGEYRDIIQEIERLRGILASRERRLQIINDELLDVKEQDLIDDEPVVVTVTHQGLLKRTPITEYRAQGRGGRGVRASGTREDDYVEHLFTSTTHDWLLFFTDHGQCYWLRVYDIPEGSRTAKGRSIRNLIQIAPDDSLRAVLAIDFLNSHYVLMATRGGQVKKSTLEAFSRPRADGIIAIETTADDELLEAHLTSGDACVVMASSSGHAIRFDEEDVRPMGRKARGVRGIRLTEGAEVVGMFTLADDPHVLTVGQKGYGKRTPLTDYRQQGRGGKGLVTMNTTDRTGPLVTVKGVTAEEDLMVITTAGTMIRTEVEGISAMGRNTQGVKVINLRSGDRIADVTRLADPAEHSGGAEEAEDPAPAT.... 1271
82 0.000e+00UniRef50_UPI000360EE0A DNA gyrase subunit A n=4 Tax=Succinivibrionaceae TaxID=83763 RepID=UPI000360EE0A  ali  37  1MSDNGNNNPPEDQNSEEQNIRTVKITEQLKTAFINYAMSVIVDRALPDVRDGLKPVHRRCLYSMYINGFDSSGKTVKSAKVVGDVIGKYHPHGDTSAYDTLVRMAQDFSLRYPLVIGQGNFGNLDGDKAAAMRYTEIKMSRLTNEMVMDLGKETVDQVPNYDGSELMPSVMPNRFPNLLVNGSSGIAVGMATNIPSHNMREVIDATLALMDNPDIGTDGLMKHIQGPDFPTGGIIYGVSGVREAYETGHGSIIIRSRTHIEKPGEKQSIVIDEIPYNVNKKELVTRINACIREKIIEGMTDVNDYSGRHDVRIVIELRKGEAPEIILNQLFKRTNMQISYGINMLALNDGHPEVMNLKQILGAFIKHRREVVTRRTVHDLRRSRSQAHLLEGILVVLSNIDEVIRIIRESQNKTEAKEGLMNRGWISDRQAENILNMPLHRLTGMAYNEVQDTYTDLVAKIRGFLAILENDAVLEDVIRKELIQIREDYGDKRRSEI-QGERPEITMEDLIVPETAVITMSRTGYVKYQPLAEYREQKRGGRGKRAARVKDEDVIDNIYIVNTHDTILCFSSIGKVYPLKVYELPTSSSQSKGLPIVNLLALEENERIISILPVDKFDDERYLMITKKGLIKKTRLSLFKNLRKNGILAIRFMEGDSLAGSAITEGKDVIGVFSSNGYAVVFNEYYGAQDGADSDAPEAEDDTAEDIPEAEDTEDSDDDVSVSAEK------DISSYRPSGRSSRGVRAIKFKQDGGMVLTVLQVQKDDQIVLITSDGILIRTKVEQIRVCGRFSQGVKLINISDNSELIAVEKVLSEDLENDAEPDSENTGASGEAPE 962
83 0.000e+00UniRef50_UPI000DE3CC84 DNA topoisomerase (ATP-hydrolyzing) subunit A n=2 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE3CC84  ali  37  4....ENQFDEEAMASSTSLSSHIFIEDEIKKSFIDYAMSVIVARALPDVRDGMKPVHRRIIYAMHNKGNFSNKAFRKCAKTVGDVIGTYHPHGDQAVYDAMVRLGQDWKQRHTLIDAQGNFGTRDGDPPAAYRYTEARLHKLAEYMTKDLDKSTVKFAPNYDGSETEPRLLPARWPVLIVNGQAGIAVGMATNIPSHNLGEAIDASLLVMDNPEATVDDIMAVMPGPDFPTAGYILGKGAIRNAYETGRGSIRVAGKWEIEPKKGNTRIVVTELPFDCSAVATVKQIDELRKDKIIDGIADVVDE-TAKELRFYVEVKRDADPNIVLNWLKRKSNLVTTFPVNATVLDSGTPVVMGMKQMLTEFVAFRRQTVRLRTIHELNDARRSLTFTIGLYAAVSQVDRVIGAIRSSENNEVALGKLLDNYRLTEEQAKHVLEMRLGKLTNLGTQEIGEKARDLVKEIEFHNTVLNDRSVLDGIVRNEMLEIKHNHAEPRLTQIIDVDPDDIDDEDLIEHKEIVVTFSRSGYVKRTGLEAYREQKRGGKGRNGMDTKDDDFIQDAIYCSTKTPLLIVTSRGMSHLIKAYMLPEGAPSAKGRFIGNFINNMPGETVTNILPMPVAEEEFVLFVTDYGKIRRNQAADFAKINRNGKIAIKL--DDELVKVMLARDTDDIMISTREGMVCRFLVDDCRIMSRTSDGVKAISLREPDDVIDACVVEHEEFILTVTANGYGKRSSSFGYRRTSRGGQGFKGGNINEQTGNLVACFTAREEDGLVLITDGGQAIRTRVDQVKKLGRATRGVKVFTVPDGQRIVSVARVEATDEPEAAATPETEAPASVE... 937
84 0.000e+00UniRef50_F2I4X1 DNA topoisomerase 4 subunit A n=63 Tax=Bacilli TaxID=91061 RepID=F2I4X1_AERUA  ali  33  4..................DIQELSLDEVMGDRFGRYSKYIIQDRALPDIRDGLKPVQRRILYAMYHDGNTSDHAFRKSAKTVGNVIGNYHPHGDSSVYEAMVRMSQAWKNRMPLIDMHGNNGSMDGDPAAAMRYTEARLSKLADELLKDLNKDTVDTILNFDDTEEEPVVLPAGFPNLLVNGSQGISAGYATEIPTHNLGEVIDAVNYYIDHPKAKVETLMKYLPGPDFPTGGIIQGKDQLIKAYKTGRGKVVVRAQTEVESLKGRKQIVITELPFEVNKADLVRKMDELRLNRSIDGVMEVRDESDRSGLRIIVELKKDADADQILQYYFKHTNLQINYNFNMVAINKQRPEQVGLIAIIQAYIDHRKDVVSRRTQYDLNKAQSRRHIVDGLIKAISILDQVITIIRNSSDKKDAKNNLISEYQFSQAQAEAIVTLQLYRLTNTDITALQEEKLSLNEAINQYQAILSDETILMKLIQSELKAIKKAYATDRLTKIEEVEEIKIKKEFLIPDEEVVTVVTRGGYIKRSSLRSYQSSNFADLG-----LRDGDHVLYLAAHSTLDNLVLITNKGNYIFQPVYEMQELRWKDLGEHLSQRIPIASDEKIIQVYPYAKDSQDTIVLATREGMIKQSKLSELKKIRNKASQIMPLSSPDEVVNCYLVNNQSDVILFTALGFSLRYQISEINTVGLRAKGVISINLKDQDQVVNFDQVDEDQQILLATQRGYMKRMRWRDIQTMTRAKRGLMVLRVKSKPHRLVQALEVESTQEVYLYTSNGELSQIKAVDVPLHERYSNGSQIIDEGRLGELLDVIPLYRKDPEK................. 818
85 0.000e+00UniRef50_A0A1Y0VNP1 DNA topoisomerase 4 subunit A n=280 Tax=Bacteria TaxID=2 RepID=A0A1Y0VNP1_PEDPE  ali  35  4...............NQSKIQELALEDIMGDRFGRYSKYIIQERALPDVRDGLKPVQRRILFAMNKDGNTHDKAFRKSAKSVGNVMGNFHPHGDSSIYEALVRMSQDWKLRVPLIEMHGNNGSIDNDPPAAMRYTEARLSEAAEEMLNDIDKETVDMVLNFDDTEYEPTVLPARFPNLLVNGATGISAGYATEIPPHNLGEVIDAVLYTIKHPNPSLEKLMEFVKGPDFPTGGIIQGINGLKQAYRTGKGRVVVRSKTSVEEIRGNKQIIVSEIPYEVNKALLVKKIDEIRVMKKVDGIAEIRDESDRDGLSIAIELKKDVDARGILNYLFKNTDLQVSYNFNMVAINKLRPERMGLKEIIQAYVDFQKEVITKRTKFNLKKAEDRLHIVAGLIKALSILDQVIKTIRGSKDKKDAKQNLITSFDFSERQAEAIVSLQLYRLTNTDVTELKSEAKTLNDSIDEFNNILNNPNELSKVLSAELRQVKKRYATPRLSEIQEHIEEVVDRTITVPEEQVMVLVSQSGYLKRSSLRSYKASAEED------GLKEGDFTVFKKELNTLDHLIMLTNKGNLIYRPVHEIMETRWKDTGEHISQAIGLADDEIILKAFDVKNFDEPMSFIATSDGYIKRTSLKDFKPGRTYRKKAIKLKAADKVVNVAKLSTKETILLATRNGYGLRYDLIEVPEVGPRAAGVKSMDLRE-DEIANFVLVNDHDQIGLITNRGSFKKMKVSEISVTSRARRGVQILRELKKEHRVADIEVVEPGEAFEVRTSRGLIHDIIPLEHPLNERYSNGSFLVDVDSEGVPVSMNLKELDSEIL................. 814
86 0.000e+00UniRef50_A0A1B3NDD5 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Bosea sp. RAC05 TaxID=1842539 RepID=A0A1B3NDD5_9BRAD  ali  37  2.......TEQSAPPSGGDRIEIADISKIFSQDYLDYAMSVIVSRALPDVRDGLKPVHRRIMYGMETGGYDANKPYKKSARIVGDVMGKYHPHGDQAIYFALVRLAQDFKVRHPLIDGQGNFGSMDGDPPAAMRYTESRMTRLAHFLTADIDKSTVDFKPNYDGKEKEPVVLPARFPNLLVNGQMGIAVGMAANIPTHNLGEVIDACLIVLDNEHATLDDLMQVMPGPDFPTAGIIMGRSGIRQAYLTGRGSIMMSGIAVIEEKRGRNRIVITELPYDVNKTFLVEKIAEYVNMRPFGGISDIRDESNQESMRVVIDLKPDAEPAVVLNALRKYTDFQSTFGYNATCLNKGQPNEMGLQQILTEFVAFRRECVTKRTIHELDEARGRQLKQIALYAAMDRIDQIIALIRSAEDDDEAASKLMQTFRLSLPQANAILAVSLKQLSRMGRDKIANELRTIAATIRGLLPILSDRRVLDNVIRMEFMEIRDKHANKRLTRIETTEADEIDNEALIERRDVVVTLTSSGYVKRTELSAYRAQRRGGKGKTGMETKDDDFVISTSVCTTRTPLLAFTAKGHVYAIKAHRLPDANANAKGRPIVNFIELKPGDSVRSLVPLPEDRNLNLLFVTDFGDVRRSRATDFSDLRRGGKIAMRLENEDKIVSVLVARDDEDILLATASGQVIRFPIEDLRIIASNSTGVRGISFDGKDFVVDACILAHTDANWIVNEQGRVKVTRMAEMAAEERFGYGKRTYRVTGRSGSIVGALPVNDDDGLVIVTDGGQAIRTRVSDISSLGRATKGVRVFSLPEGQKVSGVARIASDDGAEEGLEDDGTPSSP..... 947
87 0.000e+00UniRef50_A0A1E5A6Z4 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Rickettsiales bacterium (ex Bugula neritina AB1) TaxID=1868285 RepID=A0A1E5A6Z4_9RICK  ali  38  3.............ENLNENYLKIRLDDEMKESYIVYAVS-ILERAIPSVFDGLKNVQRRIIWTMCEIN---TQKLRKSATVVGDVMGKYHPHGDSAIYQTIVRLSQDFVLLHPLIYGHGNFGSIDGDGAAAHRYTEIKLEAIAYHLFEHIYENTVDFRPNYDGTRKEPVLLPVKFPHLLVNGAQGIAVGYATSIPPHNLKEVLEATRHLIHNPNCSIDDLLEFVKGPDFPTGGIISSKEEIRQAYKSGNGIIKIRGKTHIEKESK---IIITEIPHQLTKSALLEKIIQETKNGKIENVQSVRDESDNH-IRIIIELKKHSNIDVTLNQLYTFTPLLSSYRIYLLALNEGKPQLFNLKSILQSFIDFRHEIISRKAVFNLKEYEKRINVLFGYVIGLDNIDELVDIVKHSPNTEYLKDVLGKKSWLNKIQIKSILEMRLQNLTKMEKNKIINEINEIKKIIIEKREILTNVNLRNNIIEKELLEIESKFSKPRYTKIEDQY-NSLKDEDFIPKEDMVITLSQEGFLKRTTVDVYKEQHRGGKGSLGFSTNQEDFVQDILIANTHDTLLLFTSSGIVFSLKTYKIPLSSKSSKGRFTTNFIPLKENDKIIKILPITNKNMKSIFFVTNLGHVRKNSIDDFKNLRADGKIYMKFMNNEQLINVCFCDENTEIMLFTKFGKAIRFNATDVRESSRNSVGVRGCILYENDEVISLITSKSNSLIFTTTAEGFGKCTKIDNYRKTKRGAKGVINIKLS-KTDYVVSVENIKKDDDIIIITSRGQTLRFSIEEVRNSSRSTKGVKVINMDKNNKVVSVTKLKEEQHETI................ 839
88 0.000e+00UniRef50_A0A2D6K625 Uncharacterized protein (Fragment) n=1 Tax=Nanoarchaeota archaeon TaxID=2026764 RepID=A0A2D6K625_9ARCH  ali  41  318...................................................................................................KLKDKEEVFSVKVNSSCHSFIANGFVN------HNTEAKLNRMAEEMLKDIDKETVDWKPNFDNSLKEPKVLPSKLPNLLINGSSGIAVGMATSIPPHNVTEVLNGAIALIDNPELSIQELMTIVPGPDFPTGGIITTNNTLTHGYAHGRGKVRIKAVIDIEDNK----LIIREIPYQVNKSELIQAIAQLVRDKRITSIRNISDQSDRHGIRVVIDLKKDADPNVVINQLYKYSRLRVSFSLNLLALVNNEPKTLGLKQFLSHYIDHRKEIITKRTEYDLREAEKRIHILNGLIIAIDNIDEVIAGIKKSPNVQSAREFLMNTYQVSKIQAQAILDLRLQKLASLEQQKIKDEHTELLKKIEAYKDILGDIQKVYAIIKQDAEELKEKYGDKRRTQIVEGDDEDVDMEELIKEETMVVTKTHAGYVKRISLDEYKTQRRGGKGVKAAGMKDEDFVELLYVSSTHDYLLIFTDKGQMSWLKVYNIPEGSRQAKGRHISNLIQLKEDEKVSAIIPVRDFKDGYLFMATKNGTVKKTSLMDFSNVRRGGIRALTLDEGDTLVGVKYTTGDREIILATKNGVANRFKEADVRPMGRTARGVRGIRLAQNDAVIGMLAAEEGSHILTITNKGYGKRTPVTDYRLCNRGGKGVINMKITEKNGPVKAVMLVQGDEEIMLVSKNGIAIRMKCSDISVIGRSTQGVRVMRLSDNDTLAAAAKFVIEDEENGEIPE............ 1035
89 0.000e+00UniRef50_A0A0S7BSU3 DNA topoisomerase (ATP-hydrolyzing) n=2 Tax=Anaerolineaceae TaxID=292628 RepID=A0A0S7BSU3_9CHLR  ali  35  1..............MNKQETKPIDIEHEMQQSYLDYAMSVIISRAIPDARDGLKPVQRRILYAMYDMGIRPDSDYKKSARIVGEVLGKYHPHGDTAVYDAMARLAQDFTIRYPLVDGQGNFGSVDGDSPAAMRYTEAKLDKFSMEMLEHIDQNTVDFSRNFDDTLSEPVVLPSIIPNLLVNGASGIAVGMATNIPPHNLGEVIDAIIYILHQWEIGVDDLMKFVKGPDFPTGGIIDARNELVSAYATGRGRLMVRGRVHLEDMKGRSRLIITEIPYQVNKSGLIERIAQLVRDNVIEGISDLRDESDRQGMRIVIEIAKTGEPEKILRKLYKHTPLQTTFGIILLALVDNSPRVLNLKQALKVFIDHQLEVIRRKVTFELEKAERRAHILAGLLIAIQHLDEIISIIRNADDEKQARSEIIQKFQLDEEQAQAILDMPLKRLTHLEXXXXXXXXXXXXXXXXXXXXXLASPERMREMLEKELLDVRKKFSDPRRTQIAVLGEGISSKELLTANTLVEADEVFVGLTPD--------GKIGRCEAAKAAEKDFAIPPWIVRSDTQKTVYIVSDTGKAFGIYVETLPKVDAFADGIDFGSISGWSSEEKISAIFNEKNGDESAVITITENAILKKTSTAELPFASTQSFTLCKVNPGDRLLTVLVSEENSNIMLVSRKGMAIRFDQTDLRPMGLIATGVNGMKLKEDDRLAAALLVTETDYCCFVSSSWGLGKIAVNEFPKQGRYGQGVIAIRMAD-DDSIAGAVKLESGKTLLLLYGKGKTRPIRLTTVKQIKRARQLESTIKMV-NQNVMGLSLVLLEKAEKGTEPDEEPETATK.... 825
90 0.000e+00UniRef50_A0A2D8VIP3 DNA topoisomerase (ATP-hydrolyzing) n=125 Tax=cellular organisms TaxID=131567 RepID=A0A2D8VIP3_9GAMM  ali  38  2................SEELERRFVSDEMKESYINYAMSVIIGRALPDVRDGLKPVHRRILWGMHQAGHTHDKSYSKSARSVGEVMGKYHPHGDQALYDTMVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTESRLDRLSSHMLXDINKDTIDMVANFDDSESEPTVLPSRLPNLLLNGSDGIAVGMATKIPPHNLNEVAAAVRFHTEKPQIDAMEYMEYLKGPDFPTGATIHGIDGILDMYRTGQGRFHIRSEAEVRDDSSGKKIVITSIPYQVRKASMLKGIAELVTKETIKGIRDIRDESSKEGXRVVIEVKNNADPHAILNQLYQSSRLQESYSANMMGILNGAPVQLDLSTILHTYVRHRETVIERRTQFELNKAEARAHILEGLMAAQKRMTEIIEVGRNSDSRDEEKYPKIKRFDFSEKQAKAIAERRLYQLTKLNXXXXXXXXXXXXXXXXXXXXXLDSRKRRLEILISELEEVVEKHGDERRSHI-DPTPLSMDREDLVAERALVISLTQDNYIRHLPVEAFRLQNRGGKGLKGVATKDEDAPAAIVTCFSKDRLLIFTDQGRVYGLRAWETPLASRYGRGTHIRNLLGIRDDEKVISILPMDNPEGHYLIFATSQGRIKRSNLSDXVRINRNGKYALKFASEDSLVQVRPATDADHVVLVSSGGYACRFLPAEVRVQGRVSQGVSGMKLQSGDSVIGMIVTDDDTSVLTISKYGMAKRSRLDGYRKTNRGTKGVRTMALSDE-DMIVGVRQIPDSDQLFMLTGSGMMIRMPATQTKELGKVTKGTRIMELRGADKIIFVARLPAE--LIDGDEDDSDGANEEE... 898
91 0.000e+00UniRef50_F9DMZ2 DNA topoisomerase 4 subunit A n=52 Tax=Bacilli TaxID=91061 RepID=F9DMZ2_9BACL  ali  33  4................SETFQDLPLEEVIGDRFGRYSKYIIQDRAIPDARDGLKPVQRRILYAMYHEGNTHDKAFRKSAKTVGNVIGNYHPHGDISVYDAMVRMSQHWKLRHEMIDMHGNNGSVDGDSAAAMRYTEARLSAIASEMLRDIRKETVDFAPNFDDTELEPTVLPGRFPNLLVNGATGISAGYATDIPPHALHEVIDAVFMRLKNPEASVEDLMTVLPGPDFPTGAIIQGTDGIRNAYKTGKGRFVIRATWEIEQLKGKSQIVVTEIPYDVNKANLVKKMDELRHDRKLDGIAEIRDESDRTGLRIVVELKKDMDGNAIMQYLLKHTDLQITYNFNMIAIAGRRPMLMSLPMLLDAYIDHQKEVITRRSTYDIRKAKDRLHIVDGLMKALSILDEVIKTIRASKDKKDAKRNLIDAYQFTEVQAEAIVSLQLYRLTNTDXXXXXXXXXXXXXXXXXXXXXXXXEKKLVAVLVKELKAIRKQFSEPRRSVIEEKIEEKVDLDILVPSEEVMVSVTKGGYIKRTSMRSYSASNGTGQEMK-----ESDYNLLEAAMNTQHHLLLFTSSGNYIYQPVHELPDIRWRDLGQHLSSIVGLEPNEEVDVIGLETFDENLSILTAASNGNVKLSKLTDFQVQRNRSFKAMNVKKGETLVGAQVVTGKEDVLLVSKQAYALRFSLFELAITGIRTGGVRGLHLKAEDELVAFEVITEQKNIFVATQRGSVKRMNISEFEVASRALRGVTVLKELKSNPRVVDMKAVKEDEQFVLLTTKDQKIEIDPMLLKNTNRQSTGSSIVDEAKEGKIVQVAVMKKED.................... 807
92 0.000e+00UniRef50_A0A1H3U755 DNA topoisomerase 4 subunit A n=2 Tax=Bacteria TaxID=2 RepID=A0A1H3U755_9BACI  ali  36  2..............QEKDRYLDLPLEDVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHVDRNTADKPFRKSAKTVGNVIGNYHPHGDSSVYDAMIRLSQDWKMRHLLVEMHGNNGSIDGDPPAAMRYTEARLSSISSELLRDIDKNTVDFMPNFDDSDTEPVVLPSRYPNLLVNGSTGISSGYATDIPPHHLGEVIDAAILQMEKPDCTLDELMAHIKGPDFPTGGIIQGAEGLKKAYETGKGKIVLRGKAKVEDLGGRQQIVINEIPYEVNKANLVKKIDELRIDKKVDGIAEVRDDTDRTGLSIVVELKKDADAQGILHFLYKNTDLQVTYNFNMVAISNKTPKLLGLKQMLASYIGHQKAVVTRRTTYDLTKAKERAHIVEGLIKAISILDDVIQTIRSSKDKKDAKDRLQAAYGFTEPQAEAIVTLQLYRLTNTDXXXXXXXXXXXXXXXXXXXXXLASEAKLIGEIKRELKDTKKKYADERRTAIEEIEDLKINLEVVVPAEDVMVTVTKEGYVKRTSLRSYAASNGEPPGMK-----ETDRLLHSMEMNTTDTLMLFTLKGSFLFLPVHQMPEIRWKDSGQHVANIITMDSDEIISAIPVKDFTEERYLLFTTKNGMIKRTVLSEYKAQRNSKLMAIKLKKDDEVIHAALTDGHQDVFIATHNGFGLWYSEEEVGVTGQRTAGVKAINLKADDFVVASLTFPEGENLFLVTQRAAYKKMKLSAFEKSSRAKRGLVMLKELKRPHRVAALLAVKKNGKVWMEGEKGMQEAVDVSTVRHSDRYTNGSFLLDTTETGEVADVW-YEPGEDGNTVKNDANEAAPPDKVT. 826
93 0.000e+00UniRef50_A0A1Z8PDP6 DNA topoisomerase (ATP-hydrolyzing) n=73 Tax=root TaxID=1 RepID=A0A1Z8PDP6_9RHIZ  ali  41  2...TSEGNTNEDLSIKNENILNHTLNKEMKTSYINYAMSVIIGRALPDVRDGLKPVHRRVLYGMYEGGHTSERKYSKSARSVGEVMGKYHPHGDLSIYDTMVRMAQEFSLRYPLVDGQGNFGSIDGDPPAAMRYTESRLDKISKHMLEDIEKKTVDFQPNFDDSEMEPTVLPARLPNLLLNGSDGIAVGMATRMPPHNLTEVAGAVRMHVDHPNIPIEDYMSHIKGPDFPTGATIHGIDGILDMYSTGKGRFHVRSKCDVRDDSKGKMIIIHEIPYQVKKSDMLVHIADLVSKGSVIGIRDIRDESSKEGIRVVIEVKNNADPNAVLNQLFKSSRLQESYSANMMGILDGRPVLLTLPVILHTYVEHRESVIERRAKFELQKAEARAHILEGLVKAQDRIDDVIAVGKASSGRDQFESVLQSKFDFTEPQAKAIAERRLYQLSRLDXXXXXXXXXXXXXXXXXXXXXISSRPRRLQILIEELDEMVEKHGDERRSTI-DPMPLSMDREDLIEERAIVISLSEDNYIRHMPVESFRLQNRGGKGLKGVTTKDEDFPKSILTCFSKDRLLIFTNHGRVYGLRAWETPSASRYGRGTHIRNLAGIRDEEKVISILPIDNPDGHYLIFSTLNGRIKRSRLSEYVKINRNGKYAIKFAEGDSLVSVRSATEEDHVVLVSAMGNACRFMPAEVRVQGRVSQGVSGMKLSKGDRVIGMIVTDDETSVLTVSKHGMAKRSRLDGYRRTNRGTKGVKTM-ALDKDDEIVAVRQIPDNDQLFMLTSKGMMIRMASVQTKELGKVTKGTRIMELRNSDKVIFVARLPSSLVDIRSSEEEE.......... 906
94 0.000e+00UniRef50_B1XQN0 DNA topoisomerase (ATP-hydrolyzing) n=56 Tax=Cyanobacteria TaxID=1117 RepID=B1XQN0_SYNP2  ali  35  1MSNQHKFMAQQLDLLQSGHIIPTALHVEMEQSYMEYAMSVIVGRALPDVRDGLKPVHRRILYAMYELGLSPDRPYRKCARVVGDVLGKYHPHGDQSVYDALVRLVQDFSTRYPLLAGHGNFGSIDNDPPAAMRYTETRLSPVSFEMLAQISEDIVDFTDNFDGSQQEPVVLPVQLPILLLNGSSGIAVGMATNMPPHNLGEVVDGLIALIDDPEIEDEKLWAVIPAPDFPTGGEIVDLAGVRDAYRTGRGIIPMRGIVHLERKRDVNALVVTELPYQVNKAAWIEKIADLVNDGKISGISDIRDESDRQGMRVVIELKRDAEPEKVLKLLYKKTALQSNFGAILLSLVNNQPRQLSLKAILQEFLEFREETVTRQYRYELEQKETRQHSVEGLLLALNNLDAVIEILRNAADGTTAKQQFQAALGFSESQSDAILAMPMRRLTGLEXXXXXXXXXXXXXXXXXXXXXLSDRHELLKALKRELRSLKRKFADPRRTRLPDVPSPEPEPVTVEAEPDTPAATPKKKQLTETSHVAIAASGGVYWGNDDAGLLDEEPTIFKAQIGTQKKLIVCTDQGKAFPVAIADLPYQEQRDKPQLIDLLPDHDDHQPITQFLLPDNLAEYDLLLLTAQGRIKRLPAIELESFTSRGLSLIKLKDKDTLKFACFVKGGEQVAIAVSSGRVLHLPVHEIPVMGRTSQGNQALRLRFNEQIVACVPCQRHNELYLISEEGYGKKLAASSLRLGKRGDMGNHVMRFESKTDLLLTLFVPDQQESLLVKDSQENLDLLPFSKFNLTEKDSPGQKLVKLSGGDRLVNCYL......................... 842
95 0.000e+00UniRef50_M4CAZ5 Uncharacterized protein n=3 Tax=rosids TaxID=71275 RepID=M4CAZ5_BRARP  ali  36  62....SGDNNNSNDGGGDPRIVPFELHKEATESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKSARVVGEVLGKFHPHGDTAVYDSLVRMAQSFSLRCPLIQGHGNFGSIDADPAAAMRYTECRLDPLAEALLADLDQDTVDFVPNFDNSQKEPTVLPARLPALLLNGASGIAVGMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGGTIMGNLGVLDAYRTGRGRVVVRGKTKVEMKTKRNAVIITEIPYQTNKATLVQKIAELVENKILEGISDIRDESDRNGMRVVIELKRGGDPALVLNNLYRHTALQSSFSCNMVGICDGEPKLMGLKELLQAFIDFRCSVVERRERFKLSHAQKRKHIIEGIAVGLDNVDAVIQLIRKASAPSAA---LQSEYGLSEEQAEAILAISFRRLTALERKKFTDESSSLTEQITKLEQLLSSRTNILKLIEQEAIELKDRFSTPRRSVLEDSDSGDLDDIDVIPNEEMLMAISEKGYVKRMKPDTFNLQNRGTIGKSVGKLRVDDTMSDFLVCHAHDHVLFFSDRGIVYSTRAYKIPECSRNAAGTPLVQ----NSGDELKWVRCCSS--DDLVAMASQNGMVSTCDGVRTLSRNTKGVTAMRLKNADKMASMD--------IIPSSLRKDIEVKSEE----------------------ASAEKQSTGPWLLFVCENGYGKRVPLSSFKPSRLNRVGLIGSK-FAEDDRLAAVFVVESDEQVVLVSQTGTVNRIKVRDISIQSRRARGVILMRLDHAGKIQSASLISAADVEEEGEGVQSLEEATASL.. 896
96 0.000e+00UniRef50_A0A0G4GL74 Uncharacterized protein n=1 Tax=Chromera velia CCMP2878 TaxID=1169474 RepID=A0A0G4GL74_9ALVE  ali  35  46...TETETASLVPPSPGNNVIQIELETELSTSFMSYAMSIILGRALPDARDGLKPVHRRILWAMSELGLSPSSSFRKCARVVGEVLGKYHPHGDVAVYDALVRMAQDFVMQAPLVDGHGNFGSVDGDPAAAMRYTESRLTGFATDLSSSGEKDAVDFLPNFDGNEKEPTVLPARVPNLLLNGATGIAVGMATNIPPHNLGELVSACIALIDERELPDDDLFQLVPGPDFPTGGIILGTQGARKLYTTSGGGVRVRARVHVEEIQKGRALVVTELPFSVNKALLLERIAALATEKKLEGIADVRDESDRDGMRVVIEIKRGAIPSRVLQKMWKLTNLESSFSGNLVAIGENQPVRLTLRAALLFWLDFRFSTVRRMAAAELLRREARAHVIEGLLSALRRIDDVVDVIRASSDQGAARDALSKEPFLSAEQAQAVLRLTLGRLTSLEXXXXXXXXXXXXXXXXXXXXXMKEDQKVWDVIKEELKEVAAKHARPRRSLIVEIDENGEPDGQDEADEVSALMLTAKGYVKRLSLSDFAMQGRGTGGKAGVRLSENDYLRLFCVCSEKDRVLVFTSDGFAFDLPPAIVPMAGRTARGVPAPSVLPISAETKVAAVLREDEAEESFLVLMTNAGLMKRCKLSALRRVTARGLRVMTVNEGDSLKFARVCSEADSIVVGTRGGRALRFSASDLRVTGRTSRGVRAIRLRPGDLVEDMEVLPGGSSLLCLTSNGIGKRLRASDLRVQARAGMGSIAMKFKKGSDFLTCLRTCPPETDILVGTRKGRMVRQSTDPISVQGRMAKGVRVQKLPAGDAVASVAFVPKGVGIPQEDAEDTDANEEPSLDE 957
97 0.000e+00UniRef50_A0A1F4UMC4 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=candidate division WWE3 bacterium RBG_19FT_COMBO_34_6 TaxID=1802612 RepID=A0A1F4UMC4_  ali  42  4.......................DITNQMQKAYLDYAMSVIVSRALPDVRDGLKPVHRRIIYAMQDQGIYYTSKFQKSASVVGEVMKNYHPHGNEAIYESLVRMGQDFSLRYPLILPQGNFGSIDGDPAAAMRYTECKMSKISDELYKDIDNDTVDFELN-DLQNQEPLYLPSLLPNLLLNGSSGIAVGMATNIPPHNLREVVDGILYMIDKSEATSYDLVDYIQGPDFPTGGIIYDQSEILHMYATGKTRIVVEIRITEELKNGKTRIVVTEIPYQIQKSTLLTRIAELAKIKKIDGIVDLRDESSRNEIRITIELKKGAIAKKVQNSLYKYTQLQSTFNANMVALINNEPKLMPLKMILEEFIKHRQQVVVRRTIFLLKKAKSREHILLGLKIALDNLDEVIKLIRSSKDADAAKISLINKFGFTDIQAQAILDMQLRRLAALERQKVEDELKEIIKTIKDYEGILISGEKIINIIKTELIDLKEKFGDDRKTKVIKGKVGEISDEDIVVNEKCIITLSDSGYIKRMKKNAYRIQGRGGTGVSGGELKEEDQITTIRTCDSHDWALIFTNSGKVYKMRVWEIPEYTRKAKGTPIINFLSVPQEETVQALLTISEEKSGYILLVTKHGRIKKTELEQFENIRTSGIISINLTDKDSLVFADISSGKNEVLLVTLYGQSIRFKEDDVRPMGRSAGGVTGIKIHQNDYVIGAIIINKDKYLLSISQNGYGKKTPLNEYRLQTRGGSGIFTYKISDKTGLLVSARLIDGEADMLVVTEQGMVIRMDSAQIPSLGRYTIGVRLIKLKEDDKVTSAAIVEKESDINTPILEENDEE....... 907
98 0.000e+00UniRef50_A0A2X0WIL0 DNA gyrase subunit A n=1 Tax=Anaerobiospirillum thomasii TaxID=179995 RepID=A0A2X0WIL0_9GAMM  ali  36  45..TDGDDTIADQNSSVNSKMPTVKLEDEIKKSFIDYAMSVIVDRALPDVRDGLKPVHRRVLYDMYDLKIWYSGQTKKSARVVGDVIGRFHPHGDAAVYETIVRMTQWFSMRAPLIFGQGNFGNIDGDGAAAMRYTEIKMTKIAEMMLQDIDKETVDSYPNYDGNEQIPEVLPTRFPNLLVNGASGIAVGMATNIPPHNLSEVIDGSIALLDNPDLSLDEIMRYIPGPDFPTGGFIVGNSGIKEAYATGRGRCIMRARTHVEEDKGRKTIYVDEIPFVVNKSAIVKQIADLVHEKKIEGIAEVNDLSDKDNVRIAIDLKRDAYAEAVLNNLFDKTQLQTSFAMNMIALVGNHPKLLSLKEILSEFVSFRREVVTRRTVYMLRQDRRKAFLNEGLIVAKANINKIVDMITSSANAEDARHKLMSEPWLSEEQARAILAMQLQRLTHLASDEIQADYKALIENIKGYLEILNNPVRMNEVIRDELIEVKNTYGDKRRSDFIEDYGKR-SKGDFIAKQDVVITLSGEGYIKYQDISSYEARNRGGKGRAAAKLKDEDYISNIVVANTHDHLICFTSHGRAFSTLVFDLPTSNRTWRGRPIQNLFEIEEGEKITALLPISEFDERFIFMATQNGMVKKTRLSEYRNKRSNGIKAINLAQGDELIGAQISTGDDDIFLFTTHNRAIHFIEAELVSSPRVGSGVRGIRLRDGAKVVALIVVNPDPKVIIATANGYAKRMHLNAITIKNRAGIGIKSMGQFERNGLCIGAVLAHDNGEFMLITDQGQLLRVGIDSIPLASKAAGGVIAMRPYEGESVIALQSI--DEDVVAASNKVSEGRAKDKQ.. 982
99 0.000e+00UniRef50_A0A149QS33 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Gluconobacter oxydans TaxID=442 RepID=A0A149QS33_GLUOY  ali  36  1MSDTTDAIPVVPVHAG-----TISFAEEMKDSYLAYAMSVIISRALPDVRDGLKPVHRRILFGMRESGFTHDRPYRKSARAVGDVMGKYHPHGDSSIYDAMVRMAQPWNNSVVLIDGQGNFGSIDGDSPAAMRYTEARLARGATPLIADLSPDRADMVPNYDESEREPLVLPARYPNLLVNGGAGIAVGMATNIPTHNLGEVIDGTIAMMENPFITVQEMMQHIKGPDFPTGGVIHGSENVLRAYETGRGSIPLCGVYEIQTSKSRESIVITEIPFNVCKATLVESMGALVNSGEIQGVTAVRDESDRKGMRIVVDVRRDTDARLVLNLLRKHTSLDSSFAVNAVCVDSRRPITMGLLEMLAHFIEFRRKTIFERSDYKLGKLRDRMLLQVALFVATLNLDEVVRRIRSARDRSHAEELLMQMDFLTPPQAEAIVRQRLSFLAAVEQDAVYQDIEAALEEIRYHEGIVSDPDKLDALMKEELLAIKQAHGVPRRTRILTEDIKLLTQDDLVEEKAVILTMTARNYVKLTPVDAFREQGRGGKGRAGMATRDNDFVIASLACSNKDTLLLFTNRGVVHQLKAYEIVEAAPAARGMPVVQYLPMAGGEFITVMVQPEDDSGASMVFVTSTGDVRRSEAKAFSSIRRNGKIAIRLQESASLVTVIPCTEADDIVLYTSNAKAIRFPVADLRVSGRESSGVRGVRLAKDARVLGASMASDERFIMTVTENGFGKRFSSHDLRISARGGQGVEIGRFGPVTGPLVGCRVVGEDDSITLVTDKGKTIRLRASDVRKTQRAGRGVTLFDIAKGEKIVDIAVITGSQAEEE................ 901
100 0.000e+00UniRef50_A0A2E5HWG8 DNA topoisomerase (ATP-hydrolyzing) n=4 Tax=Chloroflexi TaxID=200795 RepID=A0A2E5HWG8_9CHLR  ali  37  1..............MEIGHIQAIDIDEEMQASYLSYAMSVIIARAIPDARDGLKPVHRRILYAMHDMGISPQSGHKKSARIVGEVLGKYHPHGDQAVYDAMARMTQNFSMRSMLLDGQGNFGSMDGDTPAAMRYTEARLHSISTQLLTDIQKNTVDFINNFDDTLQEPTVLPAAFPNLMVNGSTGIAVGMSTSIPPHNLAEVCGALELMLKNWKIQVQDLMQYIKGPDFPTGGLVITHDGLASAYGSGRGKITLRARIHVEETRGRQRLIVTELPYQTNKASLISRIASLARENRITGITDLRDESDRQGMRIVIDLSKSVEPDMTLQQLFKLTPLQTTFSIILLALVNGEPRLLTLKQALRVFLEHRIEVVRRRSQFDLKKAKDRAHIVSGLIIALDNIDTVITLIRESKDVPAARKALMKQHDLSNTQANAILDMPLRQLAQLQXXXXXXXXXXXXXXXXXXXXXLKSKTKVREMVASELRKLSHKYSDNRRTHIISHSKQTTTANIIVPNEDSWITLTQSGTLARTNNSRRPSLTGTM-------------PISILRANTQDVLYLITNDGTASAITVGSIPTASNPKLGVPIDSISAITNNTSVIAALAMNSSTAGQSDDFTSQGGIKRLLAKDLPGPSASVFKIIKLSDNSKLVSACWIEPSQNVLMFTSAGKGIRFDCNIVRTTGLSAGSVQGIRSNKTDRLITCTAGNENTEICLVSQNGKAKRTLVSQFPLQGRGGSGVQACKLDA-GQKLSGAAPAISNTEIVIVTSNKKAYTHKITDLPLIGRSASGSQICNLRDKEQVTRMVLC........................ 804
101 0.000e+00UniRef50_A0A0L0MJQ0 DNA topoisomerase (ATP-hydrolyzing) n=3 Tax=Acholeplasmataceae TaxID=2146 RepID=A0A0L0MJQ0_9MOLU  ali  43  26...............NIGAIKFVEINQEMKKSFLSYAMSVIVSRALPEIKDGLKPVQRRILYGMKELGVYHQASYKKAARIVGDVMGKYHPHGDSSIYDAMVRMSQEFNYRYPLVDGHGNFGSIDGDAAAAMRYTEVRMSKIAMELIKDIDQNTIDFTKNYDNSEQEPIVLPTSFPNLLVNGSTGIAVGMATNIPSHNLVEVIDALIAYINNKDIDIEGLMQYIKGPDFPTGGELIGVNNLKEAYTTGRGRVFIRAKTSVVKNKNKFSVIIHEIPYQIKKSSLIEKIALLTKDKIIDGITDLRDESSREGIRIVIDLRKDINPQIFLNNLYKHSQLHISFNFNMIALVNGTPHLVNLKKILEEFFLFRIDVINRQKQFELAKASTKKHLIEAAVKVLNDIDNTIELIKKAKDIRDAQTKLMDKYNFDELQSKSILEMSLQKITNLEIEKIKKEEQNLITQIQSCQEIINSQTKKENIFQKDLLRIKKIFQDERKTIINDVNEFNIPNENLIEEERILITVTHKGYVKRLNLDIYKKQHKGGKGVNGITVNTDDFVKHFVISTTHSYQLFFTNKGKVYQLKGYQIPFFSRQSKGIPLVNLIPLEKGEFLTSLTSVDDFKNDCLVLITKKGLVKRNNIKEYENIRKKGKIAFPLKINDEVLCVLNTSGKQDIILAASNGRAIRFNEMSIRKTTRQGVGVKGMNIDNNEVIVGAAVVSPEQDILVLTEKGYGKKTKSKEYKKQKKGGKGQKTFKITSKNGQLVMLDTILPNEEIILISDMGKVIRIENKDVALTKKLTQGYRLFNLENNQKLVLAVVVPKEKD................... 840
102 0.000e+00UniRef50_A0A1A9QF27 DNA topoisomerase (ATP-hydrolyzing) n=4 Tax=Mycoplasma TaxID=2093 RepID=A0A1A9QF27_9MOLU  ali  42  3.STRQKTIEKIIKSLDKDTVLDRNIVSEVEQSFLDYAMSVITARALPDLKDGLKPVHRRIIYAAYQERLFHDAKFKKSASLVGTVMGSYHPHGDSSIYDALVRMAQDFSLRYPLIEGQGNFGSIDGDSPAAMRYTEARLSKLGKYFLDGIEEECVDFMDNYDQSRKEPVVLPTLIPNILINGSTGIAVGLATNIPPHNITEVFDAILALIKNPDLTLGEISDYIKGPDFPTGGEIFKYSGVRDYFSTGSGTFKLRSKIEVEEQQKRNLFIIKEIPYGVKKTKIIGKIVSLIKPSKSENIVDIRDESNLEGIRLVVECKNDISKQVILNNLYKFTQLQTSYSPNLTVLINNEPRKISILELLKLYLEHQLEMLKRRTIYQLGVLAKRLHILEGRIKISSDIMEAIRIVNTSDNPEE---EIQKKYELSQEQLEDIFKLTIGSLKKISVDKLQEEHTTKTASKISKEELXXXXXXXXXXXXXXXXXXXXXFGDERRTRINETNSGRIDFYQLFHFKKIIISLTKKGYLSQIPLETFRLHKRGGIGVKGAFVHKDDAPKMLLVCFGSDDVLFFSDAGKVYRKKAYEMNLSTNKNKSISYNVLQGMDKNEKIITIIRDDYLENKYLFFATKNGIVKKTKLSMFARINVSGKKAIRLKDGDALKFVIKIEENSQICLASSAGRMVKFDSKDLRPRSRNTFGVYGLRLKENQELVSASSTAEGEYVLSISENGKGKLTHIDDFNIVKLGRKGTKAQRINEKTGNILACTIVNTSDEILLMTNSNKLNRFRVSDISVQNRVTSGVKLFNLDGKEKLVYFAK......................... 826
103 0.000e+00UniRef50_A0A285TU02 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Thalassospira xiamenensis TaxID=220697 RepID=A0A285TU02_9PROT  ali  38  1.......MGLLDPSNAVEARTTINLEDEMRTSYLNYAMSVIVSRALPDVRDGLKPVHRRILYTMDESGVVSSKPHKKSARVVGEVMGKYHPHGDSAIYDSMVRMAQPFQMSSILIDGQGNFGSIDGDSPAAMRYTEARMSPLAESMVADMGRDTVDFIANYDGTLLQPTVLPTRFPNVLVNGGAGIAVGMATNIPTHNLGEVIDATLAMIDNPSLTLDEFMAFVPGPDFPTGGVVMGAQSIRTAMETGRGSLYVSGVAHIEENGGRQRVVLTELPYAVNKEELVSRIGALVDHQRILGVSDLRDESDGTGIRVVIDLKRDTDPNLVLSKLRKYTRFCTTFSVNATCLNANQPEVMGAMRMVSEFIQFRKQVVRRRTIYLLDEARDELAKQIGLYAARSCVEEVVKIIRSSKDPEAARIGLMAMSFLSMAQAKAVLALRLSSLTALELDKISERIQTIITSIRGYEEVLNNEETLKDIIRNELAEVRAKFSTPRRTRIESFAPGDVSEDELVEQKAVFLTLTGQGYVKITPLDAYREQSRGGKGRAGMETKEDDFVQKSMVCNTRTPLLFFTSRGIAHTVRAYKLPETAPNSRGKPIVNFINLRPGETIAAVLPLPDFDGKFMMFVTDRGEVRRNRATDFSQVNKSGKIAMKLEPTAALINVLLAEKGDDIALSTSSGRSVRFPITDVRVSGRNSTGNKGVALTASDRVVGATILRHEQYLLTVTERGYGKRFSSYDFRTTSRGTQGVKAGTFSKVTGDLVACACVLPTDSLVLVTDGGQVIRTPVSEIRVMSRTARGVKLFEIPDDQRIVDVAIIANEEE................... 934
104 0.000e+00UniRef50_A0A2E2N667 DNA topoisomerase (ATP-hydrolyzing) n=2 Tax=Phycisphaerae bacterium TaxID=2026778 RepID=A0A2E2N667_9BACT  ali  36  12....NESGAAGSGDNGAGRIIDLKIETELQDSYLTYAMSTIMDRALPDVRDGLKPSQRRILVAMHDLKLRPGKKHLKCAKICGDTSGNYHPHGESVIYPTLVGMAQSWKMRVPLVDPQGNFGSIDGDPPAAMRYTEARMHVAATDLLEDIELDTVDRQPNYDDRLTEPVVLPGKFPNLLINGGMGIAVGMATSLPPHNPAEILDAIVRVVDNPDISTLELMADDKGPDFPTGGVILGRKGIVDAYESGRGRVTVRGECHVEDMGGRQQLVIDSIPYSLVQNTLVEKIVDAVKDDRIKEISDVRNESGRSQTRIVVELKKGADPAVIENQLFQHTPLQQTFSIINIGLVNRQPRTLGLKQLIERYIDHRVVVIRRRTEHLLREAKKRAHVLEGMIYAVTDIDEVIKLIRSSRTREEAIAKLMERRYLTRVQAETIGSMRLIQLVGLEXXXXXXXXXXXXXXXXXXXXXLATPARVAQMIKDDCDEMKSRYPGDRRTRI-DEAAGDIDIEALIREEDMVVTITRGGYVKRVAASTYEAQGRGGKGIRGADAKGEDVITNLFVASTHADLLCFTDTGRVFKLKVYELPEMSRTSRGRSIQNFLQLRDGEKTWAYLAVDDFESKTLTFVSRGGIVKRTPLKAYANVNKSGLIAVGLKEGDELFDVLLTNGTDDVMLVADTGMAIRFNEADARDMGRSAAGVKGVDLPDDARVIGAIAIPMEADLLTVTENGYGKRTPVDEYRVQTRGGKGRTDIRVNPRNGKPVTAIGVYDTDDIVVVTQNGQLVRMAADSISRYGRGAQGVRVVSINEGDKLVTVARVVEDTDSGDSDAPTDSPASE..... 928
105 0.000e+00UniRef50_A0A1V4R8G5 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Campylobacteraceae bacterium 4484_166 TaxID=1956165 RepID=A0A1V4R8G5_9PROT  ali  43  1..........MSDLLNQEHITDINIENSIKGSYLDYSMSVIIGRALPDAKDGLKPVHRRILYAMSELHLSPKTPYKKSARIVGDVIGKYHPHGDSSVYDALVRMAQPFSMRVPLVDGQGNFGSVDGDNAAAMRYTEARMANPAVDIISDLDKDTVNFTPTYDDTGKEPTLLPTKLPLLLANGSEGIAVGMATKIPPHNLGELLDAVLHLVDNPDATIEDLMGFIQGPDFPTGATIHGKQGFTDAYKTGRGKVKLRAKHHIEQKGKKEVLVLDELPYQVNKAKLILQIADLAKDKIVEGISEVRDESDKDGTRVVIELKKDAMAEIVLNNLYKTTPIQTTFGVILLAVYNKEPKIFNLKEILEVFVSHRKTVIIR--------------------------------------------------HLSAIQSQAILDMRLGRLTGLQXXXXXXXXXXXXXXXXXXXXXLKSEDRLSEIIKEEAISSKEKYATPRITNIEDSYD-DIDMEDLIPNEPMVVTITHNGYVKRVPIKLYEKQRRGGKGKVAVTTHDDDFIEKFFVSNTHATLMFVTNLGQLYWLKVYRIPEGSRTAKGKAVVNLINLKQNETIMAIIPTNDFDNKSLTFFTKLGIVKRTSLNDYSNIRSNGVRAIVLSENDEVVTAQIADTNSYLMIFTALGQVIRFEIDKLKTQGRSTKGVRGIRFNPKDYVVDADIIENEQELLTVSENGIGKRTEVEAYRLTNRAGSGVISMKLSPKTGKVIGNVFVDEEQDLMMLTSIGKMIRVDMQTIRKAGRNTSGVTIVNVDKGDKVVSIAKCPKNKEDELDIQSAED......... 774
106 0.000e+00UniRef50_A0A0J1FGT2 DNA topoisomerase (ATP-hydrolyzing) n=25 Tax=Peptococcaceae TaxID=186807 RepID=A0A0J1FGT2_9FIRM  ali  36  4...............PEENISQRPLEEVLPEAYMGYSKFVILHRAIPDVRDGLKPVHRRIIYSMNELGMYPDKPYSKSARLVGHCMGAYHPHGDSAIYEAAVRMAQPWASRCPFVDGHGNFGSVDGDPAAAMRYTEMRLTPLARLMCQDLEKDTVAFRPNYDNRLEEPVVLSSPLPNVLVNGAGGIAVGLSTNMPPHNLGEVVNGIIHQIDRPEVTPAELMNWVPGPDFPTGGFILGRAGIREAYETGRGKIILRGKAAIEPGKNGKSIVITEIPYQVNKASLAAKIETLSSDK-IEGIADVRDESDREGMRLVVECRKDAEPGEILNRLYKYTQLQESFGINLVIAADGTPKVMNLKEINAAYIEHRREVVVNRVTYDLKKAKERAHILEGLVKAIQNLDEVIAEIRAAKTPALAKAALILRFEFSEVQAQAVLDMKLQHLTHLELQGIEHEYDKILKTIISLEGILADERKVYGIIKRELKEIADKYGDERRTAILDGDGEGETQTVLAPAEPLEVLLTGKGFIKARIPGKNGHGKRRDSAVKDADIFDEDILRHKVCCTDQDQLLFFSASGRVYSLAAKLVPEAAGRAKGKALSALVPLPEGEEIVACRPLRTGAGDHVVFVTRLGQVMRSPAADFVNLRNA--EGMTLKPDDTLVTAWLSPEGQDLVLLTAQGQALRLAEADVRAMGRKSKGVRGISAAADYVAAALPVTDSAADLITVSERGWLKRTPIEEFKRQKPGGKGVTAARLLEKTGLLATALLADQGSALTALQRSGAQTRISVASLKVEARSRKGALLVAVVLDDYVIGVFA......................... 807
107 0.000e+00UniRef50_A0A1Z5KAF6 DNA gyrase subunit A n=2 Tax=Fistulifera solaris TaxID=1519565 RepID=A0A1Z5KAF6_FISSO  ali  38  94......................IELQTEISNSFLQYALSIILGRAIPDARDGMKPVHRRILYAMDQLNLRPNTPHRKCARVVGEVLGKFHPHGDVAVYDALVRLAQTFSTNYPLIDGHGNFGSIDADPAAAMRYTEARLTSLSKEILDELEEDTVDLVPNFDGNELEPNVLPAKLPILLLNGASGIAVGMATNIPPHNLRELMAGCEALIDSRPVTDEKLFKLIPAPDFPTGAIIVGTSGAKQLYKTSNGGVVMRATTQMEEKGTRTAIIVTQLPYQVNKAALLEKIAALVNEKKLDGIADLRDESDRDGIRVVIELKRDAVPQVVLNNLFKKTALQTTFSGNFLALFGGSPQRFTLREALDSFIDFRFSTLRRKAAFRLSKVEARANIVNGLLLALKHVDWIIETIQKAQDLDAARKQIEDEIGLNAEQTDAVLKLQLGQLTRLNXXXXXXXXXXXXXXXXXXXXXXXXDHTVYETMKTEFRELSVKFGRDRQSRILPEEDGEIDEVDLITNSRSVIVVTRGGYIKRMPLKTFESQNRGTRGKRGTSDSGESQVSQCFTCNDHDTLLMVTQKGVAYGLRAYQVPIATRTAKGQPIPQVLPIRSDEMITAVLPVSRFSDDEYIVATEQGWIKKTALSSFEKLTTRGLIIATVEESDSLQWCQPCKDGDDILVGSAMGKAMRFEASKLRPTGRTSRGVKSMTLREGDRIAGFNVLESEEYVLAVTSMGFGKRINTSEFRAQNRGGQGVIALHFKKEQDEMRCLQIVKEEDEILVITSKGVMVRQQVSQIPSQGRSATGVMVQKLDAGDQIVGVSIVPEMGENENEFED............ 928
108 0.000e+00UniRef50_I3TKX1 DNA gyrase subunit A n=3 Tax=Tistrella TaxID=171436 RepID=I3TKX1_TISMK  ali  40  1.......MSDTPVPPIASDIAPVTIEDEMRRSYLDYAMSVIVARALPDVRDGLKPVHRRILFSMHESGYEWNKPFRKSARVVGDVMGKYHPHGDSAIYDTMVRMAQDFSMRLRLIDGQGNFGSMDGDPPAAMRYTEARLTKAASTLLSDLDKETVDFQNNYDDTTREPTVLPARFPNLLVNGAGGIAVGMATNIPTHNLGEVIDAAIAMVNRPEITDLELLRIVPGPDFPTGGIIVGRGGSREALLTGRGSVLLRGKVEVEEIKDRMAIIVREIPYQVNKARMIERIAEAVRERKIEGVADLRDESDRDGVRVVVELKRDATPEVVVNQLYRFTPLQTSFGVNMLALNAGKPEMMTLRDMLQAFLEFREEVITRRTIYELRKARERAHVLMGLGVAVVNLDPVVELIKASPDSASARDALMDRPWLSEAQARAILDLRLHRLTGLERERIGAELREICDKILEYLRILNDRARMLEVLREELIEVRDEFATPRRTVIEE-SEFDYNVEDLIEREEMVVTVTHGGYIKRVPLSTYRAQRRGGKGRSSMAVRDEDFVSQIFVLNSHAAVLFFSTAGQVYKLKVWQLPAGTPQSRGKAMVNLLPLKEGEVIATLMPLPDDPDMYVMFATAKGNVRRNRLADFVNVMSNGKIAIRLGEGDRLVGVLPCNGGDDVVLASRAGKAIRFPVGAVRLKSRTSDGVRGISLAGSDEVVSMSIIRHRE-VDVDTRDNYAKRRWLAQLKALETGTSAVVTGDLPGDEAELAARRLEAEEEFLLVVTTRGYGKRTPVADIRIAGRDTMGVIVFKTAQDEKVVSAARLSETAEEDQNGAGEANGDGE..... 956
109 0.000e+00UniRef50_A0A1I7H5F7 DNA topoisomerase (ATP-hydrolyzing) n=3 Tax=Eubacterium pyruvativorans TaxID=155865 RepID=A0A1I7H5F7_9FIRM  ali  42  1MARKKEQKVEYHYETEDRKMKVHGLTDEMEKSYLDYSMSVIVGRALPDVRDGMKPVHRRILYGMQQLGITPDKPHKKSARIVGEVMGKYHPHGDSSIYDAMVRMAQDFSMRYPLVDGHGNFGSIDGDGAAAQRYTEARMSPFSMEMVRDIEKDTVDFMPNFDGEEMEPTVLPSRYPNLLVNGSSGIAVGMATNIPPHNLGDAIDAAVYMIEHPDCTVDDLIPVIKGPDFPTGAQILGKSGIREFYRTGTGRIRMRAKCSIEPRRGREQIIITEIPYGVNKAKMIEKMAELVKSRKIQGITEIRDESSREGIRIVIELRKDANAQIILNNLYKYSSLQENFGAIMLALVDGKPKTLNLREVLEEYIRFQKEVVTRRTEFDLKKARERAHILEGLLIALDNIDEVIRVIRSAYD--DAREQLMKRFGLDRVQAQAILDMRLARLQGLEXXXXXXXXXXXXXXXXXXXXXLASERKLMQVIRKELLEIRKNWSDPRRTEIVKDPG-ELDEDDLIVEEDAFVSVTARGY-----------AKRVPDVSKAVKPMEDDYVKHLYHTTTKQTLLVFTDVGKMYRVPVLDLQESTRSVKGTALAESCGFLTRENFVSAIAVGDFDKGSVFVITDGGAVKRIQISDLDTSRRNGISYTKLKENEKVVDV-VVDNGEDLILATKRGKGIRFSGDGIRAMGRAASGVRGIRLDDGDLVTAVTRYERGSEIVAASSGGFIKRFRASQIPQQARGGKGVFLWKSLKMTGPLTGIVSRDAEGEVVFLLEE-KCVVMKVKEVPEATRAAAG---IRCEFGESVISCAALRSTEDMPDPTGPDTPDTPDTSGP. 826
110 0.000e+00UniRef50_W2UZT7 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Candidatus Xenolissoclinum pacificiensis L6 TaxID=1401685 RepID=W2UZT7_9RICK  ali  40  2.................SSVVKVVLEKELEKSYLSYAMSVIINRAIPDVRDGLKPVHRRILYAMYSV-ANPYKIYRKSSRVVGDTVGKYHPHGDVAIYDALVRMAQKFSLREPLIDGQGNFGSVDGDQPAAMRYTEVRLSEITRFLVSDLSQNTVDFQSNYDGLESEPSVLPAGFPNILVNGVNGVAVGMATNIPCHNLAEVIDAVVLLLQSPDSTVHDLMKCLPGPDFPTGATIMGMYGIVSAYTTGKGTITLRSNTHFEEKNNRKYIIVDELPYQVNKSRLIESMASLIRDKVIDGISAIVDESDRHGIRVVIELKKGYEQEFVLNQLFTITNLQIRYSINMMVLNRNKPSLMNLKDVLATFLEYRFSVVIRRITFRLEKAQNKSNILISLYIALLDIDAVIKIVKDSGDRDEAIFLLKDYVWLTTSQAEAILNIRLQTLTKLEKNRILDELKCHIAIIEECNMLLSSQEKLTELIRDELLQIKTQHCTPRRTIIEQSGDEGVDDEDLILKEDMVVTFTNMGYIKRVKLSHYRSQKRGGKGRLGQDIKNEDFTEKIFVVDTHTEILFFSTKAKVYKLKTYLLPLSEPASRGRALVNSLNLEDGECINTIMPVTKDIDSSMVFITSHGKVKRNKFSDFHYIPSNGKLALSLSDDDMLVAVMLATSQHDVFVATYYGKSIRFPIEDIRLKGRVAGGVRGIKLSENDRVVGMDIVKNEQFILSVTENGYGKITSAYEYRSVNRGGAGIVNVATTKRNGYVVASFPIEQDSHIILVTNKGQLIRIKTSDISISGRSSQGVILLKTKKDERVVSVAQISNMQKEDDISEE............ 887
111 0.000e+00UniRef50_A0A109BMR1 DNA topoisomerase (ATP-hydrolyzing) n=3 Tax=Variovorax TaxID=34072 RepID=A0A109BMR1_9BURK  ali  37  3..................QVQPLLVQPLMEQSFIDYAMSVITDRALPDVRDGLKPVHRRILFAMHDAGNSHSKAYRKSARTVGDVIGKYHPHGDASVYLAAVRMAQPFSMSTMLIDGQGNFGSVDGDFPAAMRYTEMRLTRLTGEFFTDLHKETIEWAPNYDGTEKEPTVLTTPYPNLLVNGVEGIAVGMASRIPPHSLRAVCATTLMLIDRPDASTAEVVAVLQAPDFPTAAIVHGLDGFAQAVESGSGRIKIRSRWHEEDRGGAKAIVIDELPYQVNKAVLVGKIAELVREKKVEGIVDLRDESNKDGIRIWIALRKDESTEAVFADLASKTDLEVALSYNCVVLDGGRPKLLGLKDIILRWIAFREEVVLARHVFERKQALARLHILEAYMAALGMLDQVIALIRAAESPAVAKTGLMALLSVDELQAQAILDLRLQKLTGMELEGIRAEHAEVVAKIAGLTEIIESPERIRNVIRDELAEISNRYGADRRTEIG-VGISDITREDLIPREDVLITMTQGGYVKRLPANALRSQNRGTRGKTAMAVGDDDSISFMRQSHSHDSLMVFAKSGQVYGIKAYRIPEGTLTTKGRHIRNVIDGLDEEISAVLALPERDPETTVLTVTRSGQVKRTSIEDYDATRKGGVKGVGLDDGDMLVGAFAVKDRDDVMLISDSGKAIRFTASDARVMGRTAGGVRGIRLDGDESIVGAAIITHGAHLLCVGEHGVGKRTAVDEFPVQGRAGGGVIAFKANKKTGNLVTAMAVTEEQDLIMLASNGVSNRVAVKDIRETGRAASGVILMNMDAGQRLVSATTAVRDHEDDVPEAAVADG........ 820
112 0.000e+00UniRef50_A0A2S6S8P0 DNA gyrase subunit A n=3 Tax=Alphaproteobacteria TaxID=28211 RepID=A0A2S6S8P0_9PROT  ali  41  6...EKNKKEDNQIPPNKTGITSVSLENEMRKSYLDYAMSVIVARSVPDIRDGLKPVHRRILYSMNESNYVFNKPYRKSARIVGDVMGKYHPHGDAAIYDAMVRMAQDFSMRLELIDGQGNFGSMDGDPPAAMRYTEARLAKIANYLVDDLDKETVDFNANYDETAFEPVVLPAKYPNILINGAVGIAVGMATSIPPHNLREVIDATIALIENNNLSVSDLNKIIKGPDFPTGGIILNKEGIKSTYETGRGSCTIRSKTSFEDIKDKKAIIIHEIPFQVNKSRLLEKIAETVNNKIIEGVSDIRDESDRKGVRIVIELKRDVEHEIILNKLFKFTPLQSTFSSNILALNDGKPEQLNLKQILNAFIVFRKKIITKRTIFNLNQSRKKAHVLIGFVISNLNLDKILNLIRKSKNTSEAKKALMNEKWLSEEQSKAILELRLHRLTSLEREEIKTDLNKVIKEINNYLEILNSDEILFKKMKEEMNIIKEEFSTERKSIIENQPDENYDEIKYIQKEDIVITLSHRGYIKRVPLKNYKSQKRGGKGRTGMATRDNDFVSQIFVVSTHTKLLIFSSFGKVYSLNSYDIPEGSLQSRGKPIINILPIKNDEIVSAVINEEEWNKLYIMFATSFGMIRKNKLIDVAKSRESGKTAIKLNKDDKLIGVNLCRDVEDTFLSTTDGKCLRFPIAKIRLQGLMSKGVKGIKLKDKNKVISMCTLKQEEFIFSITSKGIGKRSSAYEYRIANRGGYGITGIIKTNKSGDVINSFPVENDDEIILVTNGGKIIRIPVKDVRIAGRSTKGVSIFKIPDTEEIVSVTKVK....................... 893
113 0.000e+00UniRef50_A0A238K761 DNA gyrase subunit A n=6 Tax=Alphaproteobacteria TaxID=28211 RepID=A0A238K761_9RHOB  ali  40  1MNDTPEAPEDTDENPPVYSGPSISITDEMKTSYLDYAMSVIVSRAIPDVRDGLKPVHRRILYHMYDGGYTPDKSYRKCAKPVGEVMGNYHPHGDSAIYDALVRMAQDFSMSLPLIDGQGNFGSMDGDSAAAMRYTEARLEKSALNLLLDIDKDTVDFQDNYDGKEREPTVLPARYPNVLVNGAEGIAVGMATRIPPHNLGEVITAALALIENPDLTSEELIEFVPAPDFPTGGIILGRSGARKAYTEGRGSIVIRSKTRVEEIKDRFAIVIDEIPYQVNKSTMIERIAEAARDKKIEGISHVQDESDRNGVRVVVELKRDATAEVVLNQLFRFTPMQTYFACNMLALNGGRPEQLNLRGFLTAFLDFREDVIVRRTAYLLRKARERSHILCGLAVAVSNVDEVVATIRASADAAEARAKLMERRWLSETQVRAILELRLQRLTQLGXXXXXXXXXXXXXXXXXXXXXLGSRDRIMSIISNEMIKVRDDFAVPRRTEIVDW-AGDMDDEDLIERSDMVVTVTAGGYIKRTPLVDFRAQKRGGKGVSGGAMKDDDVVTTLFVANTHTQLLFFTTDGMAYKLKTWRLPQGSRTSKGKXXXXXXXXXXXXXXXXXXXXDRDEDDQVVFATSAGTVRRNKLSDFTNVKSNGKIAMKFEDDTKLIDVRIAENDDHVMLVTDSGRAIRFPATDVRVFSRASVGVRGIKLLGDDKVVSMSIIRHENLLLTITSMGAGKLSSSHDYPVRGRGGMGVQAFDKAMRGGPLVASFPVEMGDQIMLATSTGQSIRVPVDGISFRSRGAGGVNVFRTGKKEVVVSVARIADQGDEDEIEDAE........... 912
114 0.000e+00UniRef50_A0A1Q7AXE8 DNA topoisomerase (ATP-hydrolyzing) n=2 Tax=Bacteria TaxID=2 RepID=A0A1Q7AXE8_9BACT  ali  43  1..........MTGPNVRERILPRLIEDELKESFLDYSMSVIVQRALPDVRDGLKPVHRRILYAMHELGLVPGRPYKKAATVVGDVLGKYHPHGDIAVYDSLVRMVQDFSLRYPLIDGQGNFGSVDGDSAAAYRYTEARLTRVAMTMLEDIDKNTVAFVPNFDDRLREPTVLPGRLPNLLVNGSAGIAVGMTTNIPPHNLSEVVQAVVRLVDHPAATIKDIRKFIKGPDFPTGAIIYGRDGIKECYEKGRGRIVIRARAIAEEKEGKQQIVVTEFPYQVSPERVHEQIRDLALAKKLEGISDVRNESD--------------------------------------------------KEGIRLVIELKRDVIPMVVLNQLYKHTQMQQTF--LKIAVDHIDEVIKLIKKSKDTPSADAALRKRFKLSEKQSAEILNMRLARLTTLEITKLEEELKDVRKFIKECKEILASKPRRMKILKEELTELAHGFGDERRTEIVADQG-EFSIEDLIAEEDMVITVSHAGYIKRLPVSAYRRQRRGGKGVIAAHQKEDDWVEHLFIASTHDYVMFFTEQGQCYWLKVHEIAQAARAARGKPILSCVAMKPDERLAALVPVREFEDQFLLFATKDGVVKKTVLSEFGNPRSVGIRAINIEKGDELIDVQVTDGKNDIVLATAHGMSIRFHEKDVRDMGRTATGVKGIELDKKDHVIDMVVVRRKSTLLTVTEKGMGKRSELDEYRVQHRGGRGIITLKRSDKTGEIIALKEVLPDDELMMITKKGIMIRVPVEGIRISGRNTQGVKIMNLTPGDLVVDVARVVK...................... 757
115 0.000e+00UniRef50_A0A2S5RA58 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Holospora curviuscula TaxID=1082868 RepID=A0A2S5RA58_9PROT  ali  40  20............................IRRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMETLGFRHDRPHRKSANVVGEVIAKYHPHGTDPIYGSLVRMAQWFSMREKLVDGHGNFGSMDGDRAAAMRYTEARLSALSDYMLADYDKETVDFQPNYDDTQKMPVVLPAAFPNLLVNGGSGIAVGMATNIPCHNLAEVLDACCLLLDHKDAELEHIMTVLPGPDFPTKGIILGTKGIGEAYRTGRGSFLIRGQAQVEYGKDRECILITEIPYQVNKSALVERIAEVARDKKIEGMTEVRDESDRMGVRIVIELKKDAAAQVILNQLYILTDLQVSFSVNMLALHRGYPVQLSLLEVLRAFLEFRREVVVRRTQYYLRKDRETIRILIGIYIAISHIDRIVELIKASRDRDAALQALITQIWLSQEQASAILALRLHRLTGIGXXXXXXXXXXXXXXXXXXXXXLRDDHKIDALMKEEFLHIKEKFGSPRLTKLQGEYLHQ-SPEDFVACEDMVVTVSVNGYIKRVPLDAYRSQKRGGRGKSAMDVREEDAVSQIFVADTHRPLLFFTSKGIAYQMKVHELPLGTTTARGKPLIAFFPLERDEKVATILPLPDNVPYFIIFATSHGNVRKNALLDFLTIRANGKIAMKLEDGEQLIRVLLANDDQDILLSTHQGKSLRFPVQELRKTGRNSTGVRGISLKPEDYVISMTLLNNEEFVLCVTTKGCGKRTSSYEYRRAHRGGQGVASMEVTARTGSIIQAIPVKAQDQILMLTNTGQLLRCPVKDIRISRRKTQGVRVFRLAKGETVVSVAVISPD..................... 890
116 0.000e+00UniRef50_Q0BST5 DNA gyrase subunit A n=1813 Tax=root TaxID=1 RepID=GYRA_GRABC  ali  40  1MSDHTNPPSAPPDDDPNGGLMPVTLEEEMSRSYLDYAMSVIVSRALPDARDGLKPVHRRILYGMQESGYTADKPYRKSARINGDVMGKYHPHGDAAIYDALVRLAQPFSLRVPLIDGQGNFGSMDGDPAAAPRYTEARLARSASFLLNDIDRDTVDFQPNYDDSEMEPRVLPASYPNLLVNGADGIAVGMATKIPTHNPTEVIDATLAMIDNPDITLDELMTVIPGPDFPTGGLILGRSGIRSAFETGKGSITVRARTDFEEVGGRQAIVISEIPYQVNKATLQERMAELVRAKQIEGISDIRDESDRSGVRVVIELKRDATPDVVLNHLFRFTQLQISYGINMLALDGGQPRLMGLRDVLSTFIRFREDVILRRARFELNKARDRAHLLVGLAIAVANIDEVIRLIRQSPDSTSARIALMERDWLTEVQARGILELRLQRLTGLERDKIHNEMQEVAARIGELLEIIGSHIRRMEVMREELAVIRAELNSPRRSEINDSLADQ-DDESLIEPGQMVVTITRDGFIKRTPLDVFRQQHRGGRGRAAASMRGDDIVTRSFNAHTHQWVLFFSSGGKAYRQKVWRLPEAGPTAKGRALVNLLPELGSDGITAVLPLPQWEGLHLVFATASGGIRRNRLSDFKNVRASGLIAMKLAQGDEVISATPEERAAYLRYASARRRSAAGEEDQIEVMEADDSEVTVDDTALSPERIA-GLEEAEEFLLTVTIAGFGKRSSAYDYRVSGRGGQGIANINLAPRNGRAVAAFPVRPGDDVMLVTDAGRLIRVPADQVRITGRSTMGVTLFRVDKDEVVTSVFPVLETESVDDNGDDAD.......... 924
117 0.000e+00UniRef50_A0A2B9WX11 DNA topoisomerase (ATP-hydrolyzing) n=3 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2B9WX11_BACCE  ali  40  4................EEKVKELPITNALADGWIDYAMSVIISRALPDVRDGLKPVHRRILHAMNELNNAYNRPYKKSARIVGEVIGKYHPHGDSAVYDTMVRMAQAFKMRVPLVDGHGNFGSIDGDSPAAMRYTESRMAKVSHELLRDIDKNTVDFQDNFDGAEKEPVVLPARLPNLLINGTEGIAVGMATSMPPHNLREVCTSIIEQMDNPEITIEELMEIVKGPDFPTGGTILGDEGIKKAFSTGRGSITLRGTIEREFVDGYEAIIIKQIPYQVNXXXXXXXXXXXIVQKGMDFIYDIRDENSHDKLRIVIQLKNGVNPDRVVKYLYKHTQLQQSFGIINLALVPTKPKVLNLKEMIEQYIKHQREVIQRQLQFDLDKKEKEMHLLDAVIRAIGNIDETVRTIKAAKTKEEAIEGLYNLLGVDEKQAAHILAMRLQRLANYEVDEQRAAHNQVGLEIKSLKEKLASQEVMDRIIKEDLQEMIEIYGEDRATVIAP-PADAISDEELIEREDVVVTMTRNGMVKRIPQAEYRVQRRNGRGVNGMGTFDDDNVKHLQIANTHDTLMFFTNKGLVYKTKAYQIPLTNKDSKGVSIRTIFDMQDDEYVQAILAIEEFNSEQTVVFTKQGIVKRTRLVEYNRSARNGILAITLNDGDEVVNVGLTSGDMYVTAITRYGKSITFEESDVKVVSRSGKGVKGIDLASKDEVVSLSIHRGFSQLFIATSNGIGKRTPLSEFRIQKRGGKGVRAITV--KDGLVIGTCVVEEDEQLILLTKQGIIIKMLAKEISSFSRNAQGSSVINLKDGDELIAVDRNSEQEDEEVALEDEAQE........ 842
118 0.000e+00UniRef50_A0A0F9NHC3 Uncharacterized protein n=2 Tax=marine sediment metagenome TaxID=412755 RepID=A0A0F9NHC3_9ZZZZ  ali  41  7.................ENIQEVLLKDEMKSSYIDYAMSVVVGRAIPDVRDGLKPVHRRLIYAMTDNNWVFTGPHVKCAKIVGETLGNYHPHGDAAVYNSLVRMGQNFSLRYPLIHPQGNFGSIDGDPPAAYRYTEARLSRIANELIEDLEKDTVNFQPNFDSSSKEPKYLPAKLPNMLLNGTKGIAVGMATSMPPHNLKEVCQGIISTIDNPDISVVELMEVIKGPDFPTGGIITSTSGIYNAYAYGKGNIPIRGKVDEETKGKVKNLIISEIPYLLNKTTLIEGIAKLIRDGVLKDIRDLRDESDRKGMRIVLELKKGAQPPIIKNTLFKRTRLLTNFNVNLVLINDGKPKILNLKELIEEYIKHRSDIIFRKAAFQVKKAKDRLHKVDGLIIALNDIDNVVNIIKSSNDSKDARTKLKDKYKLSDIQVKAILEMPLSRLTNLETKKLKDEQISLNQQITELTKILESEELRLSIIKKQLIELSNKYGDERRTKIVEEEIHDISRKDLVKKEPTIVILTKNHYIKRMSPQDYRTQRRGGRGKRGMTINEEDFISDLFVCSTHDTILFFTSKGRVYTIKCFEVPLQQRTAKGRPIINLIRIREGEEISSMIPINNFDNDFLIMITKKGIAKKIQLKKFSKIPKSGLRAQGIRPNDNLVSVKMLSNEQDIFIATKLGFAIRFDESELKEQRRTTMGYKGLSLREGDEVIEGLLVNIDDIILTLSQKGYGQRTYVKEYRKTRRAAKGVKNIKLTKVTDKVIDVK-ISTDEDILVGTKNGQVIRVPIDSIRITHRPSKGVRVIKLYKNDSVTSIGKCEKQ..................... 811
119 0.000e+00UniRef50_A0A1D6GES2 DNA gyrase subunit A chloroplastic/mitochondrial n=4 Tax=Mesangiospermae TaxID=1437183 RepID=A0A1D6GES2_MAIZE  ali  38  95................KERILPVELHKEATEAYMSYAMSVLLGRALPDVRDGLKPVHRRILYAMHEMGLASRRPFRKCARVVGEVLGKFHPHGDTAVYESLVRMAQDFSMRYPLVQGHGNFGSVDADPPAAMRYTECRLDSLAEAMFTDLELNTVDFVPNFDNSQKEPSLLPSRVPSLLLNGSSGIAVGMATNIPPHNLGELVDVLSVIIENREATLQELLERMPGPDFPTGGTILGNQGILEAYKSGRGRIVVRGKTDIEEKSKRTAIIIKEIPYQTNKATLVQKIAELVEDKVLEGISDIRDESDRTGMRVVIELKRSADPAVVLNNLYRHTALQSSFSCNMVAILDGQPKLMGLKEILQAFLDFRCSVIERRARYKLSQALERKHIVEICSKCL--------------------TCSCAEFDLSEKQAEALLDITLKKLTSLERKKFVDEAKTMSEEISKLNELLSSKKLIFQLIQQEAADLKSKFSTPRRSVIDDSISSEVDDIDIIPNEEMLKILSEKGYAKRMNPDTFSLQHRGTIGKSVGKMRMNDSTSDFIVCQTHDHVLYFSDKGIVYSARAYKIPECTRTATGTPLVQLLPLSDGERITSIIPVSEFENQYLVMLTVNGYIKKVPLNAFSSIRSTGIISIQLVPGDELKWVRHCGNDDLVALASQKGRVIVNSCDKLRALGRNTRGVCAMKLKEGDMMAAMDIIPATPWLLFIAESGIGKRVPLNAFRQSNFNAVGLQGYKLPADC-RLAAVFVAESDEQVVLVSQSGTVNRIKVKDISIQSRRSRGVILMRLEHAGKI.............................. 897
120 0.000e+00UniRef50_A0A0G1FVP0 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Parcubacteria group bacterium GW2011_GWA2_43_9b TaxID=1618828 RepID=A0A0G1FVP0_9BACT  ali  41  6..................NIKSQEIIQEMQTCYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMWDMGLRSTAKLRKSATVVGEVLGKYHPHGDVAVYDTMVRLAQDFSMRYPLVQGQGNWGSLDGDGAAAMRYTECRLTPLAEEMMQDIDKDTVNWTDNYDGTRQEPMVLPAKLPQLLLNGSLGIAVGMATSIPPHNLTELVDGISYLIENPKSTSEDLTKFIKGPDFPTGGAIYDRQAIVQAYSTGKGAIVNRATAEIEDKKGAKQIIISAIPYQVNKASLLETIAELVKDKKVDGIRDIRDESDKDGVRIAIDLKSEAYPQKVLNRLYKLTDLQKTFHLNMLALVDGLQPQ------------------------------------------VLPIDAIISTIRKSADKEEAHVELCKKFKLSDAQATAILEMKLQTLAGLEXXXXXXXXXXXXXXXXXXXXXLKSPKKILGVIKDELAHLKAKYGDDRRTKVFAAPVGEFKEEDLIAEEDCIITLTDGGYVKRMNPKNYKAQHRGGKGVSGITTREEDVVKYLACVNTHDNLLFFTNTGRVFQTKAYEIPEASRVARGQAMVNFLELGPKEEVNALVAFKENDENYLVMTTKDGIIKKTAIADFANVRRSGLIAIKLGKDDFLRWVKPSSGKDEIIMVTAKGQSVRFRESDARPMGRSAGGVRGLRLKKGDAVVGMDIIKATQELLVVMENGYGKKTELKQFKIQRRGGSGIKAAQVTAKTGQIVTAEILEDGEDIIAISKRGQVIRTSLGSISLLGRATQGVRIMKMDEGDKIASVTCL........................ 803
121 0.000e+00UniRef50_A0A166VKL3 DNA topoisomerase (ATP-hydrolyzing) n=8 Tax=Bacteria TaxID=2 RepID=A0A166VKL3_9CYAN  ali  38  1MADEHDQAGISDDGDQGERIVDLEIDRELQESYLTYAMSTIMDRALPDVRDGLKPSQRRILVAMNDNNLRPGRKHLKCAKIAGDTSGNYHPHGESVIYPTLVGLAQKWRMRVPLIDPQGNFGSIEGDPPAAMRYTEARMHHAAVDMLQDMDLSTVDMQPNYDERLLEPKVLPGRFPNLLVNGSLGIAVGMATSMPPHNPSEILDAITRVVDNPDIELLELMQDEKGPDFPTGGVIVGRRGIGEAYANGRGKVYLRGVCHVEELKDRQQLVIDEIPYNLSQRNLVEKIVEAVQDERIKDISDIRNESGRQAMRVVIELKRGADPAVVENQLYQFTPLQQTFSIINIALVGRRPVTLGLKELIEHYIDHRVEVIRRRTEHLLREARRKAHLLEGQIYAVIDIDEIVKLIRSSSTREEAIQKLMDRRYLTRHQAEQIGSMRLIQLVGLEIERLVDEYTKLVGEIEDYEEILASRPRVLQIIRDDCEAMKARYGDARRTAIED-AVGEIDMESLIREHDVVVTISRGGYAKRVPAETYRAQARGGKGIRAGTSKDEDFVQHLFVASTHDHLLCFTNTGRVFKMKVYELPEMARTAKGRAIVNLLDLKEGEKVWAFLTIKDFNSQFLTFATRGGIVKRTPLRAYRNVNRSGLIAVGLKEGDELYDVALTNGNDDILLVTSNGMAIRFAEDDVRVMGRSAAGVKGIDLADSARVIGLVAIPMVEDLLTVTETGYGKRTPVDEYRVQSRGGKGRRDIATGDRNGEAVTAVGLFDGQEIMVISRSGQLVRMAGESIRETNRGTKGVRVVKLNEGDDVIAVAPVAESDTAPGDAATTDEPPEDAGGTE 920
122 0.000e+00UniRef50_A0A1H0DMN0 DNA gyrase subunit A n=15 Tax=Actinobacteria TaxID=201174 RepID=A0A1H0DMN0_9ACTN  ali  40  22..................RIEPIELQTSMQRAYIDYAMAVIVGRALPDVRDGLKPVHRRVLYAMYDGGYRPDRGFSKCSRVVGDVMGQYHPHGDTAIYDTLVRLAQPWVMRAPLVNGQGNFGSPGNDSAAAMRYTECRMAPLALEMVRDIEQDTVDFQPNYDGRSQEPTVLPSRYPNLLVNGSAGIAVGMATSIPPHNLVEVAEGAQWALDHPDASREELIERIKGPDFPNGALIVGREGIEQAYRTGRGSVTQRAVIEIEDNRGRTCLSITELPYMVNPDNLALKIAELADSGRVQGISDVRDDSGRTGQRLVVVLKRDAVARVVLNNLLKHTELQTNFSANMLALVDGVPRTLSVDQFISNWVTHQVEVIQRRTRFRLAEAERQAHIFRGYAKALDALDEVIALIRRSPDVEEARTGLMELLEIDEVQANAILEMQLRRLAALEXXXXXXXXXXXXXXXXXXXXXXXXXXXXRSIIGEELAGIVEKYGNERRTQIIA-ADGDLSMEDLIPDEELVVSITRGGYAKRTRADQYRSQKRGGKGVRGATLRGDDVVEHFIATTNHHWLLFFTTAGRVYRTKAYNLPEAQRDAKGGHVAGLLSFQPDESIAQVLAIRDYEQPYLVLATRNGLVKKTRLGDYNSPRQAGVIAINFRDDDELIGAELVNAEDDILLVSRKGSAIRFRADDLRPMGRATSGVSGMKFRNDDAVLSMSVIRAAQYVFTITDGGFAKRSRISEYRLTNRGGLGVRAMALNEDRGGLVGGFIVEDGDEVLAITQGGQVVRSPINEFRPTGRSTMGVKFVTPKSGDSVVVVARSVEAKVIDDAEDGGVDGELDGEV.. 863
123 0.000e+00UniRef50_M9WAV2 DNA topoisomerase (ATP-hydrolyzing) n=58 Tax=Mollicutes TaxID=31969 RepID=M9WAV2_9MOLU  ali  43  2......DNQNNNQDHYHGKISPIDIAAEVRKDFLEYAMSVIVSRALPDLKDGLKPVHRRIIYAMNDLGITADKPHKKSARIVGEVIGKYHPHGDSAVYESMVRMAQDFSYRYPLIDGHGNFGSIDGDGAAAMRYTEARLAKISNYIIKDIDMETVPFVDNYDASEKEPAYLPGYLPNLLVNGATGIAVGMATSIPPHNLGEVVSALKAYIDNNDISIDEILNHILGPDFPTGALMTNGQKMRDGYKTGRGGVIIRAKVELEETAKHNRFVITEIPYQVNKSKIIEKIAELVKTKTIIGIADIRDESNYEGIRIVIDLKRDANPDVVLSKLYKFTGLQSSFTINLLSLHNNLPVLLDLKSIIKNYVEFQIQVIIRRSIFEQNKLNKRHHILQALHQVLSNVDEVIEIIKSAKTTEEAKQLLTDRYQFDDEQNKAILEMRLQRLVALEREKIWNEMQSIQERLTYLDKLINNKDEQNHVLKEQLDEIVARYGDQRRTSIIDDKLINIQDEELIPDVKTMILLSEEGYIRRIDPDEFRTQKRGGRGVS-VNAEPNDPIDIITMGKARDWVLFFTNSGKVFRTKMYNIRQYSRTSRGLPIVNFLNDLTAEKITAILCLRNTKQKYLTFVTQNGMIKRTKIAEFDNINRNGKKAITLKENDQLVSVFVTTGQDSVFVANQSGKVIRVQEDKIRSMSRTGAGVKSIKLEDNDVVVGAVSSFKLTHITTVSSKGIFKKTSVDDYRISNRNTKGIKVMNLNDKTGKFKALIPARESDLIVIVSSDGNIIKTKVSSIPTLSRTATGVKAIRLDEGQEIKAITL......................... 812
124 0.000e+00UniRef50_A0A1V5LNJ5 DNA topoisomerase (ATP-hydrolyzing) n=2 Tax=unclassified Bacteria (miscellaneous) TaxID=49928 RepID=A0A1V5LNJ5_9BACT  ali  39  2.............TDNSEKLVPVFIEEEMKHSYIDYSMSVIVARALPDVRDGLKPVHRRVLYGMLELGLRPGSAYKKSARIVGEVLGKYHPHGDTAVYDAMVRMVQDFSLRYPLVDGQGNFGSIDGDAAAAMRYTEARLAPIAEEVIRDIDKDTVDFIPNFDDSLKEPLVMPALLPTLLVNGAAGIAVGMATNIPPHNLREVVDALVAVIEKPDLKPEDLRRYIKGPDFPTGAIIVGDEEIAAYFKHGRGKLTVRARVHVEEVGGRKRIVVTEIPYQVNKTSLIERVAEMVRDKKIEGIYDIRDESDRDGMRIVFELRKEADAEGVLKDLFRYTQMQTTFGAIMIALVDGQPVVLNIKQILTEFLKFRHDVVLRRCKYELEKAEARAHILEGLKIALDNIDAVIELIKKSRDVDTARKGLMKNFKLSEIQAQAILDMRLQRLTGLEXXXXXXXXXXXXXXXXXXXXXIGSKSLRMQLIKQELLDLKERHGDNRRTQIITRSDGEQSLQEMVSDEEFILALTARGRIGRFSPQDY------GSETVSALLGEKDFLRFAFRSVSSQLLVFVCRSGRAYLSRTSFIPFASDEVKGGEISRLLHFKSEEEVIACFMPKESSERFLFVATRQGLVKKVNFSELQRIKEGGQMVIGLREDDALAGAEMTDGATELLLATRQGKSIRFSEEDVRDMGAAAGGIKGIELEADDRVVSLALVRDKAAVLSITHAGFGKRSEASEYGTIKRGGKGIVNYKCSEKSGWITAVAEAGAMDQFIVVTKKGKLKRIKAKEIKLSGRATQGAAVVNVVKGDEIVSIFPSPDPQG................... 806
125 0.000e+00UniRef50_Q2CCL5 DNA gyrase subunit A n=17 Tax=Alphaproteobacteria TaxID=28211 RepID=Q2CCL5_OCEGH  ali  40  12.....................SISIEEEMRTSYLDYAMSVIVSRAIPDLRDGLKPVHRRILYTLWENGQTNNKPYRKCGTAVGDVMGRYHPHGDSAIYDALVRMAQDFSMSLTLIDGQGNFGSMDGDPPAAYRYTEGRLEKSAEALLTDIEKDTVDFVPNYANERMEPRVLPARYPNILVNGAEGIAVGMATRIPPHNLGEVVDATLALIDNPDLTTEELIDFIPAPDFPTGGLILGRSGARKAYTEGRGSVVIRCKTRTEEIKDRYAIVIDEIPYQVNKATMIERIAEAAREKRIEGIAHVQDESDRHGVRVVIELKRDATPEVVLNQLFRFTPMQVSFACNMLALNGGKPETLTLRGFLTAFLDFREDVVAKRTAFELNKARERSHILCGLAVAVSNVDEVVATIRSSADAAEARQKLMERRWLSDTQVRAILDLRLQRLTQLGVKEVTDELEALAAKIREYLDILGSRERILSIVSDELREVRERHAVPRRTEIVDW-SGDMEDEDLIEREDMVVTVTQGGYIKRTALADFRSQKRGGKGLSGGGLKEEDVVTTLFVANTHTQLLFFTTDGMVYKLKTWRLPLGGRTSRGKXXXXXXXXXXXXXXXXXXXXDRDEDENIVFATSAGDVRRNRLSDFTNVMRNGKIAMKLPEDVSLVNARICSEDDDVMLVTDAGRAIRFPVTDVRVSGRSSTGVRGIRLQNGDKVVSMAVIRHENLLLTITAKGQGKLSSSHGYPVRGRGGQGVSATDKAMRGGPIVSVFPVELDDQIMLVTNQGQSIRVPVDGISFRSRSAGGVRVFNTAKGEEVVSVAWIAEQADEDEPGEGDAEE........ 903
126 0.000e+00UniRef50_Q3YSM2 DNA gyrase subunit A n=250 Tax=root TaxID=1 RepID=Q3YSM2_EHRCJ  ali  41  3...............DLNNVISVSIEQELEDSYLSYAMSVIISRAIPDIRDGLKPVHRRILYSMYKSGYDYGKPYKKAARVVGDVMGKYHPHADAAIYDSLVRMAQDFSLLLPLIDSQGNFGSIDGDPPASMRYTEARLARAAHFLLNDIDEDTVDFRPNYDENEVEPVVLPAEFPNILVNGAGGVAVGMSTNIPSHNLGEVVDACIAYIDNPEITFDELINIVRGPDFPTGGTILGDAGIRSAFMTGKGTIIVQGKTHLEDLPGKQAIIIDEIPYQVNKAKLIERIHELVKEKKIEGILDLRDESNKMGIRVAIELKKQVSHQVVLNQILGLTPLRTTFSINTLVLENNKPKVMSLLDIISTFVEYRREVLTRRTQFRLRKVREKAHLYIGMYIAVLNIDKVISIIRSSRDTAEATKRLLECKWLTGVQVKSILEMKLQRLTNLEKEKLELDLKSMVSMIRQYTELLKNKEALLKLIKDGLIDVKTKLAVPRRTTI-DYSHFETDVEDLIPKEDMVVTVTMSGYIKRAKLSNYRAQRRGGKGRIGQAIKEEDVITNLFVVNTHTSVLFFSNIGRVYKLKVYKLPLGEPTSRGRSLVNIFPLSENESITSVMSLPDNVEDNIVFATASGNLRRNALADFQYVPSNGKIAMVLDEGDTLISVKVCKEEDHVLLSTRLGKSIRFSVSNVRQKGRMSDGVRAIKLSSQDNVISMSIVQNEQFILTVTENGFGKRTSAYEYRTTLRGGVGVVNILTTTRNGNVVASFPVESNDHIMLITDKGKLIRIAVSDIRIIGRSTQGVTLFKTEKHEKVVSVAKIIDAKDDSEIDDD............ 897
127 0.000e+00UniRef50_A6DH72 DNA gyrase subunit A n=3 Tax=Lentisphaerae TaxID=256845 RepID=A6DH72_9BACT  ali  40  2..........SDNQQDFSTVTPQGIEKLLSDAYLQYSMSVNVGRAIPDVRDGLKPGMRRVLFAMDKLNLRKGSSYMKCARVVGDVIGKYHPHGDGSVYDTMVRMAQDFSMRGMLIDGQGNFGSIDGDSAAAYRYTECRMERLAEELLTDLDKNTVDMQPTFDGSQNEPTVLPARYPNLLVNGTTGIGVGMATSIPPHNLGEVINATVALLDQPSITIEEMMQHLPGPDFPTAGISIGFDGIRRLYETGRGGVHLRGRAEIIEKNGREQIVITEIPYAVNKENMVKKIAELVNNKVITGISSLNDESSRVGIRVVVGIKTNAMATVVINQLYKHTQLAVSIGCQFLVVDNKQPKTLNLKQLLQAYLDHRLEVITRRIKFELEKAERRAHILEGLLKAVDHIDEVIKIIRASTNREDAHNQLKERFELSNEQAKAILDMRLSQLTGLAXXXXXXXXXXXXXXXXXXXXXLANRQMRLDVVKEELIEVRDKFADERRTEMRP-GERDINYEDLIARASATITISNEGYIKRVPTEIYRTQNRGGKGVKGMETKDDDFVKQLTTACTHDYIMFFTNFGRMHWLKVYDIPEATRVSKGKAMVNLLEFEKGEYVRAMISVDDDEDRFIMMSTRNGVVKKTALAAFKNMRKKPIKAIVLDEDDDLIEAKLTDGNKKIILSTREGIACHFKESDCRTQGRVTRGCRGIRLSESDQVVAMSIVEESEDILVVTAKGMGKRSCVDDYRLTKRGAKGVRNIKL-KEGDYVVEVMMIEDTDEIIMTTMEGLMVRISAEPIRSLGRASQGVTIMKFKKSDLIISASRVVEVEADKGEDSENAESANTEEGSE 838
128 0.000e+00UniRef50_A0A2E3G6J0 DNA gyrase subunit A n=1 Tax=Rickettsiales bacterium TaxID=2026788 RepID=A0A2E3G6J0_9RICK  ali  44  1MTDDQDLLDGEELKPQEKGIGLIDINDEMKQSYLEYAMSVIVGRALPDVRDGLKPVHRRILYAMHDAGFTATRAYKKSARIVGDVLGRYHPHGDTAVYDSLVRMAQDXSLRYPLIDGQGXXGSXDGDNAAAMRYTEARMSKISMTLLEDIDKETVDFKPNFDESLEEPNVLPAKIPNLXXNGTSGIAVGMATNIPPHNLNELVXGVTALXDNPEIDVEGLMQHIKGPDFPTAGIICGDQGVRQAYETGKGSVVIRAKVSFEEKKGRDVIIVDELPYQVNKANLIVKIAELVSDKKIPGINDLRDESDRKGMRXXXELKRDASRDVVLNQLXKXTQLQNSFGINMVALVKGIPKLXNLKSVXSHYXDHRKEVITRRTTFDLKKAXDRLHXXEGXRXAXXXIXAVIELXKXSADAXXAKQGLMXTFSLTEKQSIAILEMRLQRLTGLEXXXXXXXXXXXXXXXXXXXXXLANESRVLQIIKDEHKEVIEKFGDERRTYIGX-PVXIMAXEDLIPNSQVAVLISKNGFLKXMGIEQFRSQNRGGXGINSMTTRDEDTIEHLLITXTHDFXLCXTSKGRIFKIKAHQVPEASRQSKGISMAXXLHFEEDEILTSVIDVKXFSDEFLLMTTKNGVIXKTALSAFSHFKXKPIRAINLDDNDILQWVKKTDGTKXIMLVTKFGMLIRFEESQVRSMGRASRGIRGIKTRKDDTXIAMNVXNHEDDILIXTRYGYGKNIRLSEFRCQNRGGIGVKSLTFRKKDDHVXDAVIAKRDQEFLIVTQSGTLCRQNVGKISTQRREAQGVRIVXCDDXDFVIAISVVDXTPEXETLIEKK........... 835
129 0.000e+00UniRef50_A0A1V6G5B5 DNA gyrase subunit A n=12 Tax=PVC group TaxID=1783257 RepID=A0A1V6G5B5_9BACT  ali  42  23.............................KGAYLTYAMSVIIQRALPDVRDGLKPSQRRILVAMHDLGLAPRGRFLKCAKIAGDTSGNYHPHGESAIYPTLVRLAQPWNVRHRLIDGQGNFGSPDGDPPAAMRYTEARLTTEAVELMEDLDKDTVEFVANFDGRLQEPTVLPSKFPNLLVNGSSGIAVGMATSLPPHNLGEVIDALKAVVANPAITVREILEILPGPDFPTGGIICGRGGIRSAYETGRGLITIRSRTAIEEEDGRARIAVTEVPYQLTKTKLIEAIVDQIKAERITGIGDVRDESDQKGQRLVIEVKRGEDPALVLNQLYKYTPLQSTFSIINIALVDGRPRTLTIKELLVAFVRHRFTVIRRRTAFLLAKAEARAHILEGLLRALAMIDEIIAAIKASASPAEAGRRLMDQFGFTEPQATHIRQMQLQALTGLEXXXXXXXXXXXXXXXXXXXXXMAEDGLVYDVMVEEWEDLRKRCADARRTTFAETAE-EIEDEDLIPEDRVVVTITREGYLKRTSLAAYRLQGRGGIGVRGLDAREGDVVRSVFVASTHDYVLFFTNQGRIYWLKAYQLPDLDRASRGRAAVNLLNLRENERVAQALCLEELSGGYLIFATRQGVVKRTALEAYSRPHKTGIHAILLDEGDELIAVQRCGDDDDIMLVTRNGQANRFAAGDARPMGRTAHGVRGIALRGDDRLVSLAVVREGLYLYTVCSNGYGKRTAIAEYPRHRRGGGGVRDIRTSGRNGTVVAAQAVADGDHVMLITVSGQVIRAPVTDVSAIGRGTMGVRVIRLREGDVVASLERISAEDLAAEAAAERNGGEEE..... 826
130 0.000e+00UniRef50_B8AM88 Uncharacterized protein n=12 Tax=Mesangiospermae TaxID=1437183 RepID=B8AM88_ORYSI  ali  39  1.................................MAYAMSVLLGRALPDVRDGLKPVHRRILYAMHEMGLASRRPFRKCARVVGEVLGKFHPHGDSAVYETLVRMAQDFSMRYPLVQGHGNFGSIDADPPAAMRYTECRLDVGCFDIDAIFIIGQVDFVPNFDNSQKEPSLLPARVPSLLLNGSSGIAVGMATNIPPHNLGELVDVLSVMIENPEATLQELLECMPGPDFPTGGTIVGNQGILEAYKTGRGRVVMRGKTDIETIDKRSAIIIKEVPYQTNKSTLVERIAELVEEKVLEGISDIRDESDRSGMRVVIELKRGADPAIVLNNLYRHTALQSSFSCNMVAILDGQPKLMGLKEILQAFIDFRCSVIERRARFKLSQALERKHIVEGIVIGLDNLDSVIQIIRGTSNHAMARESLIKEFGLSDKQAEALLDITLRKLTSLERKKFVDEAKSLSEEISKLNELLSNKKLIFKLILQEATDLKNKFATPRRSFIEDSASTEVDDLDIIPNEEMLLILSEKGYVKRMKPNTFNLQNRGTIGKSVGKMRMNDNTSDFIVCQTHDHVLYFSDKGIVYSARAYKIPECTRAATGTPLVQLLSLSDGERITSIVPVNEFEDQYLVMLTVNGYIKKVPLNAFSAIRTSGIISIQLAPGDELKWVRRCGDDDLVALASQNGMVIVNTCNKLRALGRKTRGVLAMKLKEGDKMASMDIIPATPWLLFIADNGIGKRVPLNAFRQGNFNRVGLQGYKLPPDC-SLAAVFVVESDEQVVLVSQSGTVNRIKVKDISIRSRSARGVILMRLEHAGKIQSASLISAAEEEEEQDPESASLISEAEEPE 864
131 0.000e+00UniRef50_Q18GY3 DNA gyrase subunit A n=113 Tax=Archaea TaxID=2157 RepID=GYRA_HALWD  ali  40  1MSSDAPERFDPETGIAAE-VETARIEREMEQSYIDYAMSVIAGRALPDARDGLKPVHRRILYAMHQSGISARSAHRKSSSIVGETMGDYHPHGDSAIYNALARMAQDFSMRNPLVDGQGNFGSVDGDPPAAMRYTEARMSPIAEELLDNIEMDTVEFTANYDDRLSEPAVLPAAFPNLLVNGSSGIAVGMSTNIPPHNLGEVIDATIHLIHHPECTVEDLMNHVQGPDFPTGANIVGQNAIYKAYKTGRGRVRVRAEFDVQDDR----IVITELPFQTNKARLVERIADNVNAGTIEGIRDLRDESDRDGIRVVVELKRGANPDIVKNQLLEH-HLESTFGVINLALVDGQPQVLTLKETLHEYLEHRRTVVRRRSQYELDEKRDRAHILEGRLRALEQVDDVVDIIRNSTDRDNAKAALRGEHDFSEDQANHIVAMQLGSLTSLEXXXXXXXXXXXXXXXXXXXXXLNNPDELDAVVEDELATIRDKYADERRTRIIE-DDGTVTHEDLIAQEDVVVVVTEDDYIKRMSLEDFRSQHRGGKGIIGTSLKDGDTVSSVYVANTHDYLLYFTSHGQVYQLKTYQIPEMSRTARGKSAVNLLELDDGEQITAVVNIDDDEERYFTMVTQSGYIKRTSVNSFQNIRSTGIIAISLGADDKLIDVEVTDGNRDIILGTRKGMAIRFNEGDVRSVGRSARGVHGIKDTDAVAALAAVDDDQDDWVLTVTEHGYGKRTDIDRYRQQSRNGKGLIDIKTNERNGHVCEVETVGISDELFMMSRKGQILRTPVDDISTVGRNTMGVIVMDLEDTDTVASVDTHPRTDDSSEADSGDGESESE..... 848
132 0.000e+00UniRef50_A0A061FQV0 DNA gyrase subunit A n=1 Tax=Theobroma cacao TaxID=3641 RepID=A0A061FQV0_THECC  ali  38  82..................RVVPTELHKEATESYMAYALSVLLGRALPDVRDGLKPVHRRILFAMHELGLSSRKPFKKCARVVGEVLGKFHPHGDTAVYDSLVRMAQDFSLRFPLIQGHGNFGSIDADPPAAMRYTECRLEALTEALLADLEQDTVDFVPNFDNSHKEPSLLPARLPTLLLNGTSGIAVGMATNIPPHNLGELVDVLCALIQNPEASLQELLEYMPGPDFPTGGLIMGNLGILEAYRTGRGRIVVRGKADIESKTKRSAVIIKEIPYQTNKSSLVEKIAELVENKSLEGISDIRDESDRSGMRVVIELKRGSDPSIVLNNLYRLTALQSSFSCNMVGILDGQPKQMGLKELLQSFLDFRCSVVERRARYKLSQAQDRRHIVEGIVVGLDNLDSVIDIIREASSNAAASAGLRNEFNLSDKQAEAILDINLRRLNLLERKKFVGESRSLMEQISKLTELLSSRKNILQLIEQEAIELKSKFSSPRRSILEDSDGGQLEDIDVIPNEEMLLAFSEKGYVKRMKPNTFNLQNRGTIGKSVGKLRFNDAMSDFIVCRAHDHVLYFSDKGIVYTARAYKIPESSRTAAGTPLVQIISLSEGERITSIISVSEFEDQFLAMLTVNGYIKKVSLNYFSAIRSTGIIAIQLVPGDELKWVRCCINDDLVAMASQNGMVILSSCGIIRALSRNTRGAIAMRLKEGDKMASMDIIPAGPWLLFVSENGYGKRVPLSSFKRSPLNRVGLIGYKFSSE-DRLAAVFVVESDEQVVLVSQSGTVNRIKVRDISIQSRYARGVILMRLEYAGKIQSASLISASAHEAEEEESATNVVATENISE 942
133 0.000e+00UniRef50_A0A2D5VB59 DNA gyrase subunit A n=1 Tax=Candidatus Poribacteria bacterium TaxID=2026781 RepID=A0A2D5VB59_9BACT  ali  40  5...........IDQHPDQKIVTRYVEEELKESYLTYAMSVNTNRAIPDVRDGLKPSTRRIIFAMGEMNLTSDRPTDKCAAVVGEVMKNYHPHGDGPIYSTLVGLEQDFGMRYPLVYGQGNFGSIDDDPPGAMRYTECRLAKIANEMLVDIKKDTVDMQPNYKESTDEPTVLPARLPNLILNGTTGIGVGYLTRIPPHNLTELVDALILMLENEANSTEDLLEIMPGPDFPTGGIIVGRSGIRDMYDTGRGSITIRARAIIERLNGREQIVVTEIPYQVKKNQLLKKIYDVVTNKTITGISDIRDESDQD-IRVVIELKRGEVAQVILNQLYKHSQMQTNYTAILLCLVDGVPKVLTLYEILNYYILHRRGVIRRRTQFDLARSERRAHILEGYRTGLNHIEEIIEIIQSADSPQTARDQLVVDYSLSEIQANEILSMTLRQLTGLERQKINDEYADLLELIEELYAILENDFLVTDMVKKDLLELKATYGDERRTEIAD-AISEFQIEDLIADEEMVVSISHTGYIKRVLISVYRRQNRGGKGVMGMGTKDGDFLEHIFIASAHQYILFFTDLGKCYWLKVFEVPEGSRTARGRSIVNLLRLESDERVTAFLPIREFDDRCIFMSTQKGTIKKCNLSLFSNPYSAGIIAIKLDEDDRLIGATLTDGNHAIVLVTKNGISIRFDEKEVREMGRTARGVRGIRLADDDQVVGMITSTQAETLLVVAENGYGKRTSLEEYRQQSRGGXGVITXKTTQRNGNVVAVKAVXDDDELIIISSXGMITRMGVKDIRTIGRNTQGVRLMSLAXDETVVDVGXI-----ISXDXKNDXEXLADXQVXE 869
134 0.000e+00UniRef50_A0A2E5IWC0 DNA gyrase subunit A n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E5IWC0_9CHLR  ali  39  10..................DIESIDIAKEMETSYIDYAMSTIVSRAIPDVRDGLKPVQRRLLYSMDELGGSPNSAYKKSARIVGDTMGKYHPHGDQALYDALVRMAQDFSLRYCLVDGQGNFGSVDGDPAAAMRYTETRLTQLSAAMLDDIDRDTVDFVDNFDGSAEMPEVLPSVIPNLLVNGATGIAVGMATSMPPHNLREIGRAIEQYIDDPEVSSRDLMRNVKGPDFPTGGIVYD-DGLEQAYTQGRGRVTVLADVQKEEVRGNDAWVIHDLPYMVNKANLVERIATLVRDKVIEDIRDIRDESDRHGMRVVIELRHDGTAWEVLNRLFKHTALRTTFSINNLALVPGQPEQLSLRRLIELFVKHRQIVVRRRAAFDLRKAEAREHLLEGYAIALEKIDDVIKVIRAADDTESARNELMQGFGLTEIQANAILDMQLRRLVRLEXXXXXXXXXXXXXXXXXXXXXLADEARILEIIRTETREVTEKFGDERKTEIRKGSAGDFNAEDLVADEDCLVTMSSAGYVKRVPANTYRRQGRGGKGIRGFRSKTGGIIEHFLVANTHDHLLFFTNKGKVYRVRAYELPEQGRDAQGHNLVNLLPVEEGERATAVLAIPNFEGDYLVFGTRRGEVKRSALTQFVSVRSNGLLAMDVDDDDELAWVRLVTDETHVMFFTRNGMSIRFMLDDIRASGRTSGGVRAIRLGANDEVVAMDLTSDEGFVLLVTESGYGKKMDVNEFRPQGRGGQGLKAINLGEKNKKVADARLLSKDEEIAFVTSDGQVMRCGCAAIRPLKRAAAGVIVMRMDAAETLLRVARLADGREVDAGKNAIVESGE...... 839
135 0.000e+00UniRef50_P35810 DNA gyrase subunit A n=34 Tax=Fibrobacter TaxID=832 RepID=GYRA_FIBSS  ali  42  1..........MSEEMVPGSQFKSLVEQDMQDCYLRYSMSVIVARALPDARDGFKPVHRRVMYSMHKLGVVPNKGTVKSARIVGDVIGKYHPHGDVAVYDTLARMAQDFSLRYPLVFGQGNFGSIDGDSPAAMRYTEAKMNNLGALMLEDLEKETVDMGPNYDESLEEPLVLPSALPNMIVNGTSGIAVGMATNMAPHNLREVGAAIHALAENPDLTGEDLMEYVKGPDFPTGAIVCGRSGIREAYLTGHGRVRVRARTEIEDAKGKPRIIVTEIPYMVNKAELCKKIADLVRDKRIDGITDIRDESSRD-IRIVIELRRDAVGEVVLNNLFKYTQLQTTFSIYNLALVNNLPKLLTLKDLLQVYIDHRLDVITRATQFDLKKAAARLHIIEGLRIATQNIDEVVKIIRQSKTTEIAKQSLQDRFSLDEIQSQAIVDMRLAQLVGLNXXXXXXXXXXXXXXXXXXXXXLEKRERRVAIMLQKLDAVVDKYGDERRTTIGEAIDDS-DDEDLIAEEEQVITLSKEGYIRRLPIDTFKAQNRGGKGIIGAGLKDEDNVEQIFTASTHSYLLVFTNKGRVYWTKVYRLPEGARNGKGRPIVNFVALTEGEKVQAIVPVRKFGGYFCVFATKKGIINKMDLTLFSRPRKAGVNAISLDEDDELVKVQLVGPKDLLMIATKNGQAVTFPISCFRAMGRGTHGVKGITLAEGDEVISLLWLKAGNKILTITEKGYGKRSEPGSYRVTRRGSKGVRNLNVTDKIGAAVFVESVADDYDLIITSKDGQVIRIKAADIRLTGRNAQGVKAITLRDGDVVKDATALPSVEDIEQDSADAKETFDKVK... 877
136 0.000e+00UniRef50_A0A2D6PW53 DNA topoisomerase (ATP-hydrolyzing) n=2 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2D6PW53_9BACT  ali  38  13................GGQIRDQLLDEEMRTSYLTYAMSVIIQRALPDARDGLKPSQRRILVAMNDLNLGPRTKFRKCAKIAGDTTGNYHPHGDQVVYPTLVRLAQDFNMRYPLIDKQGNFGAIDGSPPAAMRYTEARLAFPSVDMLDDLDKQTVGLERNYDDTRSEPTVLPARFPNLICNGSQGIAVGMATSIPPHNLTEVCDALIALIGDPDVSVLDLMEIVKGPDFPTGGIICGRTGVYRAYTTGRGLIVVRARTAIEQKGDREQIVVTELPYQVNPVTIFEKVKTLISDKVIEGISYVNDETDRDGLRLVFEIKKGHQADVVLNQLYRYTPLQNTFSMIMLALDGGRPRTFNLKEMLAAFRDHRVDVIQRRTRYLKRKAEERLHIVEGLLIAIANIDEVIKVIRSSPSTETAKERLIAQFVLSARQADAILAMRLARLTGLEVEKLDQEKVDLQGAIARYAEILGDVREVHQLVLDELEDLKVRYGDARRSEIGE-DELGIEDEALIPEGRMLVTLSHHGYIKRMSPDLYRTQARGGKGITGADTKEGDFIERLILADNKDYFLFFTTWGQVHWLKVYRIPELGRNSQGRFIENLIGMRDEERVASIIPVKEFPDHYLVTVSRNGYIKKTSLQDYSRPRSGGIIGAGLKEGDILVRVVLTDGTKDLMVSTSQGQTMRFSEQVVRGMGRGAAGVIALKFKPGDHVVDMVVAEDDGMLLTVCANGYGMRTRMSDYPTKGRGGLGVVNIKGLDRNGDVVLVRALEEGEHVILMSEGGTIMRTPADEIRLVGRGSQGVRVMRLKADDRVASGVVVQPXXXXXXXXXXXXVEAEAVE... 843
137 0.000e+00UniRef50_A0A1V5HZX1 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Tenericutes bacterium ADurb.BinA155 TaxID=1852922 RepID=A0A1V5HZX1_9BACT  ali  44  55.................PGLIDRDVAGEVKTAFLDYSMSVIVARAIPDVRDGLKPVQRRIIFGMNEEGVLPNKPYVKCARIVGDVMGKYHPHGDSALYLTLVRLAQPFSMRYTLADGHGNFGSIDGDEPAAMRYTEARMNKLSLEMVRDIDCDTVNFVDNYDGTLTEPEVLPCRFPNLLVNGSQGIAVGMATNMAPHNMSESIDATIAVAKNPNLTPLEIMQYLPGPDFPSGGTILGRKGIMDAYTTGQGSIMIRSKYHIEEMNGKSRIIVTEIPYQVNKALMIENIADLVRAKVIDGITDVRDESNKEGIRVVIEIRKDCIPEVVANNLLKHTQLQTSFGIINLCLEDGAPAILPVDKIIKDYIEFQVRVLTHRTKFLLKRDSDRLHIVEGLLLAHDNIDEVIHIIRGSKTDEESANKLHERFGLTQPQIDAILAMTLRRLQGMEXXXXXXXXXXXXXXXXXXXXXLSSRDNIIEQMIKELLEVKAKFGDERMTEITD-EAGDIENEDLIPQKNILVVLTNNGYLKRMDDDTFSAQHRGGHGITGIKTTSGDIVKLMKHTKTHTDILFFSSIGKVYRMRGYQIPDSGRIGKGMPVVNFLNLDQNEKIVAILPCDSYPEDFLFFVTEHGVVKRTALTEFASIHTNGKIAVGLREGDTLYDVKHTTGNCYISLASSNGKLCSFLESDVRTMGRTAAGVTGMNLKDGSEIIGVTTSDEGHMILVLTSLGYGKMSYAKDYRLTKRGAKGVTTVKVTPKNGKLVAVRAVEGDEDLLVITQQGIVIRTPLSEVKIAGRNTQGVKIINLEDKQRVASLSIVPHQEPGEDDGTDDEAVEGEET... 886
138 0.000e+00UniRef50_A0A1A9VJS3 Uncharacterized protein n=1 Tax=Glossina austeni TaxID=7395 RepID=A0A1A9VJS3_GLOAU  ali  43  491......NMATTSKDKMQDNIVPISIVKELEDSYLSYAMSVIISRAIPDVRDGFKPVHRRILYAMSRAGYDAGKPYKKAARIVGDVMGKYHPHGDAAIYDSLVRMAQDFSLLLPLVDGQGNFGSIDGDPPASMRYTEARLQKVSHFLLNDIDEDTVDFRPNYDGNETEPVVLPAEFPNLLVNGASGVAVGMATNIPSHNLGEIIDACMLYIDNPEVTLDELLEVMPGPDFPTGGTILGRSGIRSAFATGRGSIVVQGKTHMEDLQDRQAIVIDEIPYQVNKVKLIEKIGELIKEKRIDGITEIRDESDKSGIRVVIDLRRNAEASFILNQILGLTPLRSSFSVNTLVLSNNRPALMSLKEIIAAFVDFRKEVLIRRTEFRLRKTREKAHIYIGLYIAVLSIDEVIKIIRGAKDPAEASRELLNKEWLTELQTKAILDMKLQRLTGLEKDKLEAELSSMINLIKEYIAFLGSGEKLMKEIKNNLQEIKNRFAVPRKTSIEE-SDTDIEAEDLIPQEDMVITVTMNGYIKRVKLSHYRTQRRGGKGKLGQGLKEEDVTTKLFVGNTHTSLLFFSNIGRVYRLKVYKLPLAEPTARGRALVNIFPLSDGETITNILPSENDENQNIVFATAHGNIRRNSLADFHYIPSNGKIAIKLDEGDKLISVKVCNEIDHVFLSTRFGKSIRFVVSDVRQKSRNSDGVRGIKLAKNDSVISMTILNNEEFILTITENGFGKRTSAYEYRITNRGGVGITNILTTNRNGNVVASFPVEQGDNIMLITDKGKLIRISVNDIRIAGRSTQGVTLFKTESREKVVSVAKIEDPDSTEDSISEVENSISSQ.... 1400
139 0.000e+00UniRef50_UPI000C1D3FF9 DNA gyrase subunit A, chloroplastic/mitochondrial n=1 Tax=Olea europaea var. sylvestris TaxID=158386 RepID=UPI000C1D3FF9  ali  39  113..................RVVISELHKEATEAYMAYAMSVLLGRALPDVRDGLKPVHRRILYAMHELGLSSRKPYKKCARVVGEVLGKFHPHGDTAVYDSLVRMAQDFSLRFPLIQGHGNFGSIDADPPAAMRYTECRLRALTEAMLADLDQDTVDFVPNFDNSQKEPSLLPARVPNLLLNGSSGIAVGMATNIPPHNLGELVDALSVLIHNPEATLQELLEYMPGPDFPTGGIIMGTIGILEAYRTGRGRVIIRGKTDVESRTSRAAIIIKEIPYQTNKASLVEKIAELVENKILEGISDIRDESDRSGMRIVIELKRGSDPSIILNNLYRLTALQSTFSCNMVGILNGQPKQMGLKELLQAFLDFRCSVVERRAKFKLSQAKDRYHIVEGIIVGLDNLDRVIDIIRKASSHASAAANLKGEFNLSDKQAEAILDISLRKLTSLERNKFVAEGKSLTEQISKLQELXXXXXXXXXXXXXXXXXXXXXFSTPRCSMLEDTESGLLEEIDVIPNEEMLLAFSEKGYVKRMRPDTFNLQNRGTIGKSVGKLRVNDAMSDFLVCRAHDHMLYFSDKGTVYSARAYKIPECTRAAAGTPLVQILSLSDGERITSIVPVSEFEENQYMMLTMNGYIKKVSLNYFSSIRTTGIIAIQLVPGDELKWVRRCTNDDFVAMASQNGMVILSPCENIRALGRNTRGSVAMRLRQGDKMASMDIIPAGPWLLFISENGFGKRVPLAKFRTSPLNRVGLKGYKFSSE-DRLVAVFVVREDEDVVLVSQSGTVNRIKVRDISIQSRFARGVILMRLEHAGKIQSASLISATETDSEEVEV............ 950
140 0.000e+00UniRef50_UPI0007E74B98 DNA gyrase subunit A-like n=1 Tax=Drosophila eugracilis TaxID=29029 RepID=UPI0007E74B98  ali  40  21......KGRPMPGSPVPSDLLPVTIEEEMRSSYLAYAMSVIVSRALPDVRDGLKPVHRRILYAMHESGFTHDKPYRKSARAVGEVMGKYHPHGDASIYDAMVRMAQSWSMRVKLIDGQGNFGSVDGDSPAAMRYTEARLAKAATFLLTDIDRDTVDFQPNYDESEHEPTVLPAAFPNLLINGATGIAVGMATNIPPHNPSEVIDATLALIEKPEMELDELMEHVPGPDFPTGGIILGRSGIRSAFATGRGAVIIRARAEVEEIKDRKAIVVTEIPYQVNKATLQERIADLVRNKQIEGISDIRDESDRSGMRVVIEIKRDATPEVVLNQLYRFTQLQTSFGVNMLALDGGKPRLMGLKDVLQAFIAFREEVILRRSRFELNKARDRGHILVGLVIAVANIDAVIALIRAAPDAATARESLMGKVRLTEAQARGILELRLQRLTGLERDKIQSELSDVAKRINELLEIIGSHIRRMEVLREEMMTARAELATPRATEISDYAGDQ-DDESLIEPGQMVVTITREGFIKRTPLDVYRAQNRGGRGRTGAGTRGDDILVRSFNAHTHQWVMFFSSGGKAYREKVWRLPEASPTAKGRALVNLLPDLGSDTITAVLPLPHWESLHLVFATASGGVRRNRLSDFRNIRSSGLIAMKLDEGDSLIGVATCREGQDVFLATRKARCIRFQITDLRVAGRGSSGVRGIRLAEGDEVISLAVLNHVEA--TVEERSAYLRMANAKRRAENAAASGTALLTLLVRGTEVAATLQVLDGTDVMLVTDAGRLIRVPVDQVRVMARQASGVTLFRLNEDERVTSVFPVMEDEDEGEAPAVGGTAPASASVP. 891
141 0.000e+00UniRef50_A0A1V5HFP9 DNA gyrase subunit A n=6 Tax=Bacteria TaxID=2 RepID=A0A1V5HFP9_9BACT  ali  41  2............DTKISQNDLPANIEEIMHGAYLQYSLSVNVGRAIPDVRDGLKPVHRRILYAMQQLGLTKGHPYSKCAKVVGEVIGNYHPHGDQAAYDTLVRMAQDFSMRHPLVDGQGNFGSIDGDPPAAYRYTECRMERLAEELLADLDRDTVDMRPTFDEKNMEPVVLPARFPNLLVNGSTGIGVGMATNIPPHNLAEVIDATVRLIDNPAATVRELMQVLPGPDFPTGAAIVGINPIIRLYETGHGSLRIRGKAVIEEKDDRERIIISEIPFSLNKERLVTAIAELVQDKRILGISAISDESSRAGIRIVIDIKKAAMASVVLNQLYKNTALETTYGCQFLVVDKNRPRTLNLRQLLQAYIDHRLEVITRRAQFDLDKAEERAHILAGLLIAVAHIDEVVAIIRSSRTREEAAARLMERFSLSDRQVAAILEMRLHQLVALAXXXXXXXXXXXXXXXXXXXXXLASRSLRMAVVKQELLEVRVKYAQPRRTEILP-SEKELDVEDLIEKGVCVVTVSAGGYIKRVPADTYRTQNRGGTGVLGMETKEEDHVEHLLTLCTHDYLLFFTNRGRMHWLKGYEIPEGVRQGRGKALVNLIDLAEGEVVRAMIAVGDVPERYVIMATANGTVKKTELRQFRNLRRKGIIAIVLDEGDDLIDAQLTDGTQEILLSSEDGMAVRFHERECRELGRATRGVRGMDGKPTSKVVAMTVIDPTAELLVVSARGMIKRTRLGTYRLTHRGGRGVISIRLR-KGDRVVNALPLTGGEDILISSVKGKMVRISTNDIRPIGRSSQGVQGMRLREDDEVSGVSKVLDLPEADLAPAAEDDEELSEE... 843
142 0.000e+00UniRef50_A0A1G3PDF5 DNA gyrase subunit A n=1 Tax=Spirochaetes bacterium GWF1_31_7 TaxID=1802187 RepID=A0A1G3PDF5_9SPIR  ali  44  2.................GQTIFRDIDKELQDSYLNYAMSVIVSRAIPDVRDGLKPVHRRILHSMNEMGLQSNKQYKKAGRIVGDVLGKFHPHGDQAIYDTLVRMAQDFSLRYPAVDGHGNFGSIDGDPPAAMRYTEAKMSKIADLMLKDINKDTVDFGPNYDESMKEPLVIPSAVPFLLINGTSGIAVGMSTNIPPYNITEVVEAITKQIDNPEIEIDDIIKIIKGPDFPTGGFMYGREGAKKAMRTGRGAVIIRSKMDVEEIRGKEAIIVTEIPYMEKKSDLIIKVAELVKNDKIQGISEIRDESDRDGLRIVIELKKSAVTNVVINQLYSHTNFQKNFNIINLALDKGVPKVLNIKQTIQAYIDFRMEVIYRRTRFELKKAEERAHILLGLLIALDNLDEVIRIIRQSKDRAEAKPTLMERFGFSEIQANAILEMRLYQLTNLEXXXXXXXXXXXXXXXXXXXXXLSSDANVLRVVKEELIEDTKPYLDNRRTNIIEAEMNIFEIEDLLHEESMVVTMSHKGFIKRTPSSDFKLQGKGGVGVSAGALRDDDFIKHMFVASTHSFMLFFTDKGNVFQLKVHQIPQYSRSARGEIIKMLFGIAPDENITALLNLSDYENKSIFIATKKGVVKKVAIDEFRRINQNGKRAITLREDDSVVDVLLTTGHDDIILATKKGKALKIGEQAVRVMGRVAGGVRGIKLREGDQLCGVCPVREGGLMMLVTENGLGKRLEFDAFTKHARGTSGQMYFRYSEEKGCVAAVLSVKEEDDIMVIASKGQMIRIGSDKISKQGRTASGIRLVRITKPDFVVTASVVHKVDEDKTTETVDKADDS...... 820
143 0.000e+00UniRef50_A0A1H9CQ07 DNA gyrase subunit A n=36 Tax=Bacteria TaxID=2 RepID=A0A1H9CQ07_9BACT  ali  40  1MADETTTPPADRPNGRDGEIRTISIVDEMKRSYVDYAMSVIVSRALPDVRDGLKPVHRRILHAMNEAGYDWNKAYKKSSRVVGDVMGKYHPHGDSAIYDALVRLAQDFSMRLPLIDGQGNFGSLDGDPAAAMRYTEVRLEKVTHSLLDDIDKNTVDFRSNYDDSSQEPTVLPASFPNLLVNGAGGIAVGMATNIPPHNLGEVIDATIALIEEPTLDTIDLMQYVPGPDFPTGGLIMGRAGIRAAYEGGRGSVLMRGKVHFETNRDREIIVITEVPYQVNKASMIEKMADLVREKRIEGISDLRDESDRDGVRVVIELKRDAVADVVLNQLYRFTPLQSSFGVNMVALTGGRPEQMNLKDILAAFVAFREDVVSRRTKFLLGKARDRAHVLVGLAIAVANIDEVIQMIRTSPDPATARERLMSRDWLSEEQARAILDLRLQRLTALGRDEIGDELQKLADEIRDYLEILASRERIMSIIKDELRAIREEFNTPRRTEIVE-GGADLDDEDLIQREDMVVTVSHAGYIKRVALSEYRAQRRGGKGRAGMATRDEDFVTKLFVANTHTEVLFFSSRGMAYKMKVWRLPLAAPQARGKALVNLLPLEKDERITSILPLPDNERVHLMFATTGGTVRRNALSDFTNVNRNGKIAMKLYEGEAIAGVETCTADDDVLMTTANGQCIRFAVTDVRVKGRDSTGVRGISLGTDDKIISMTILRHFDYLRLLSQTRYAEMSASEQFVLTKRGRGGKVAMVVNSRNGPLVASFPAEHTDQIMLVTNGGKVIRVPVDGIRVAGRSTQGVTVLNTAPGEKVVSVEHISDPGEEDEMIEEAVQAAEAQ.... 921
144 0.000e+00UniRef50_A0A2E6AUR4 DNA gyrase subunit A n=16 Tax=cellular organisms TaxID=131567 RepID=A0A2E6AUR4_9BACT  ali  45  2..........EEKKYNQGSIRSRDIVQEMSESYLNYSMSVIVSRALPDVRDGLKPVHRRVLYGASDLGATWNRSHKKSARIVGEVLGKYHPHGDSSVYDSLVRMAQPWSLRYPLIDGQGNFGSIDGDXAAAMRYTEAXMGKIAAEMLQDIDKNTVXFSPXFDDSLEEPSVLPTIIPNLLMNGSXGIAVGMATKIPPHXLEELVSGLVALLDNPEVSIEXLSEHIKGPDFPTGGFIMGSDGIKSAYSTGRGXVVMRGXASXEELDGKERIIISEIPYQVXXSXLVEKIAELVRXKKLEGISDLRDESDKXGIRIVVEXKRDAXGEVILNNLYKYTQLQETFGVXXXAXVEGIPKVMGLKEMLNHFLXFRREIIIXRTKFELEEAEKRSHILEGLKKALENIDKIISIIRGSKDPDTAKKELINIFSFSEKQTKAILDMRXQKLTSLEXXXXXXXXXXXXXXXXXXXXXLTSKELQDNIIKDELNTVLDKYGDERKTEIIPF-SGDXSVEXMXAXEDMVVTITHNGYIKRXPTATWRAQXRGGKGMXGAKTKXDDYVEHLLIASTHNTMLFFTNKGKXHWLKVHQIPPGSRISQGRAIINLINCEQGEKVQAFVSVKEFNDDHIVMATXXGMIKRSSLGXYSKPRKGGIXAIXVREGDXLIQARVSSGEQDIVMATSGGKAIRFAENSIRATGRKTMGVRGIKMFEKDYVVGMLVVKREGSVLVATDRGYGKRSDVDAYRTQNRGGKGVYTVKSTPKVGNLVSIMXVIDDDDXMIITNKGIMIRQPVKXIKVIGRNTQGVKLLKLDDGAFISSITKVLKEEEKDEXNQNSEEENNKD.... 829
145 0.000e+00UniRef50_B3PN30 DNA gyrase subunit A n=129 Tax=cellular organisms TaxID=131567 RepID=GYRA_MYCA5  ali  48  54..KEGYQVKSQLLETEQNGLQPADLAKVMKSSFIEYAMSVIVSRALPDARDGLKPVHRRILYGMSELGMFHTAPHKKSARIVGDVLGKYHPHGDSSVYEAMVRMAQDFSLRYPLIDGHGNFGSIDGDEAAAMRYTEARMSKIAGVMVDGIKKNTVDFIDNYDGTEKEPTVLPSRFPNLLVSGTSGIAVGMATNIPPHNLGEIIDAVCALAKNPEITIDGLMEFVLAPDFPTGATIFNKAGLIEAYKTGRGSITMRAKANIELANGKSKIIITEIPYEVKKTEIMEKIADHLKNKRIEGISDFRDESNRDGIRVVIDVKKNAVPEVILNTLYKLTRLQTNFSFNMIALVNGEPKLLNLKECLQVYLDHQIDVTRRRLQFDLEKDLARAHILEGLKICVENIDRVIEIIKKSKTDVDAQAKLCQTFSLSEIQAKAIVDMRLGRLTGLAXXXXXXXXXXXXXXXXXXXXXLSSHEKLIELIIKELQEVKEAYGDKRRSEIRWDVMSSINNEDLIPQKEIVITLSSNNYIKRIDLEEYREQRRGGVGVSTVKTYQDDDIQDVVVANTHADLLIFTDEAKIYRVRGHEIPSGTKQSKGTPIVNIVPIQKNEKVVKIICVTDYEEQSLITVTERGVIKKTNLKEYELIRKNGKYALSLLEDDHLIDVRVVDQDEEIFIAASNSRINRFNVADVREMGRVARGVGGIRLSDDDKVVSVSSSKDGAYIFSLGAKGYGKLSLVESYRKTKRNAKGVITLNE-DKAGKLVYAAAVHGVEDLIIMTQSGIAIRISLRDINVIGRNAKGVKIINLKGSDQIVGVAKIYDEDATDRELTKEEYIEVTKEI.. 891
146 0.000e+00UniRef50_UPI0009ED0072 DNA gyrase subunit A n=2 Tax=cellular organisms TaxID=131567 RepID=UPI0009ED0072  ali  42  1.......MTTDIPDSAGPQIEPIDIVDEMKTSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAAQVGGYHANKSYNKSAKIVGDVMGNYHPHGDSAIYDALARMTQDWSMRLPLIDGQGNFGSMDPDPPAAMRYTESRLAHAATPLLSDLDKDTVDFVDNYDGSEQEPSVLPARFPNLLVNGAGGIAVGMATNIPPHNLGEVIDGVFAMMDNPAITIDELTEIIPGPDFPTAPLILGTAGARAAYREGRGSILMRCRHEIERRGDRESIVLTSIPYQVGKAGLVEKIAEAAKDKRIEGITDIRDETNRRGVRVVIDLKRDATAEVVLNQLWRHTPAQSSFPANMLAIRGGRPETLNLREILRTFIHFREEVITRRTKYELNKARERAHVLLGLVIAVTNLDEVVKIVRGSSSPAVARETLLAREWLSERQVRAILELRLHRLTAMGRDEIGEELETIAAAIKEYLSILGDRVKLYEVMRQELLEVRERFATPRLSEIAPAWD-GLDDEDLIERDEMVVTVTLDGYIKRTSLSTFRAQHRGGKGRSGMSTKDEDAISALFVTSTHNPVLFFSTSGKVYRLKVWKLPEGGPATRGRPIVNLLPSDKDEGIAAVLPLPEDEDSWVVFATAKGSVRRNAMDSFSNIPSNGKYAMRFDEGDRLIGVALLDSNDDVLLASQQGKAIRFAAEDVREQSRTSTGVRGMTLKDKDEVVSLSILEDEEFILTVCANGYGKISSAYEYRKTGRGGQGIVNIDNIERNGPVVASFRANVRDQLMLVTDKAKLIRINLESLRVLGRNTAGVRLFDVGKNEHIVSVARIDETEAEEAIVEEMIGRDAEETTPE 907
147 0.000e+00UniRef50_Q9CAF6 DNA gyrase subunit A, chloroplastic/mitochondrial n=112 Tax=cellular organisms TaxID=131567 RepID=GYRA_ARATH  ali  40  97...............DESRIVPFELHKEATESYMSYALSVLLGRALPDVRDGLKPVHRRILFAMHELGMSSKKPYKKCARVVGEVLGKFHPHGDTAVYDSLVRMAQSFSLRCPLIQGHGNFGSIDADPPAAMRYTECRLDPLAEALLSDLDQDTVDFVANFDNSQKEPAVLPARLPALLLNGASGIAVGMATNIPPHNLGELVDVLCALIHNPEATLQELLEYMPAPDFPTGGIIMGNLGVLDAYRTGRGRVVVRGKAEVEPKTKRNAVIITEIPYQTNKATLVQKIAELVENKTLEGISDIRDESDRNGMRVVIELKRGGDPALVLNNLYRHTALQSSFSCNMVGICDGEPKLMGLKELLQAFIDFRCSVVERRARFKLSHAQQRKHIIEGIVVGLDNVDEVIELITKASSHSSATAALQSEYGLSEKQAEAILEITLRRLTALERKKFTDESSSLTEQITKLEQLLSTRTNILKLIEQEAIELKDRFSSPRRSMLEDSDSGDLEDIDVIPNEEMLMAVSEKGYVKRMKADTFNLQHRGTIGKSVGKLRVDDAMSDFLVCHAHDHVLFFSDRGIVYSTRAYKIPECSRNAAGTPLVQILSMSEGERVTSIVPVSEFEDRYLLMLTVNGCIKKVSLKLFSGIRSTGIIAIQLNSGDELKWVRCCSSDDLVAMASQNGMVALSTCDGVRTLSRNTKGVTAMRLKNEDKIASMDIIPAGPWLLFVCENGYGKRVPLSSFRRSRLNRVGLSGYK-FAEDDRLAAVFVVESDEQVVLVSQSGTVNRIKVRDISIQSRRARGVILMRLDHAGKIQSASLISAADEEETEGTLSNEAVEAVSL.. 950
148 0.000e+00UniRef50_Q5YLB5 DNA gyrase subunit A, chloroplastic/mitochondrial n=87 Tax=Mesangiospermae TaxID=1437183 RepID=GYRA_NICBE  ali  40  77......DRGENEDRNGGERVVLTELHKEATEAYMSYAMSVLLGRALPDVRDGLKPVHRRILYAMHELGLSSKKPYKKCARVVGEVLGKFHPHGDTAVYDSLVRMAQDFSLRSPLIRGHGNFGSIDADPPAAMRYTECRLEALTESMLADLEQNTVDFVPNFDNSQKEPSLLPARVPNLLLNGASGIAVGMATNIPPHNLGELVDALSALIHNPEATLQELLEYMPGPDFPTGGIIMGNIGILEAFRTGRGRVVIRGKTDIESKTKRAAIIIQEIPYQTNKASLVEKIADLVENKILEGVSDIRDESDRSGMRIVIELKRGSDPAIVLNNLYRLTALQSSFSCNMVGILNGQPKLMGLKELLQAFLDFRCSVVERRARFKLSQAQERNHIVEGIIVGLDNLDEVINTIRKASSNALAAASLRKEFELSEKQAEAILDISLRRLTALERNKFVEEGKSLRTQISKLEELLSSKKQILQLIEEEAIEIKNKFFNPRRSMLEDTDSGDLEDIDVIPNEEMLLAISEKGYVKRMKPDTFNLQNRGTIGKSVGKLRVNDAMSDFLVCRAHDKVLYFSDKGTVYSSPAYKIPECSRTAAGTPLVQILSLSDGERITSIIPVSEFADQYLVMLTVNGYIKKVSLNYFASIRCTGIIAIQLVPDDELKWVKCCSNNDFVAMASQNGMVILTPCANIRALGRNTRGSVAMRLKEGDKVASMDIIPDGPWLLFVSESGYGKRVPVSRFRTSPLNRVGLFGYKFSSE-DCLAAVFVVESDEQVVLVSQSGTVNRIKVRDISIQSRYARGVILMRLEHAGKIQSASLISAADADPEDEDATA.......... 932
149 0.000e+00UniRef50_P41080 DNA gyrase subunit A n=1138 Tax=root TaxID=1 RepID=GYRA_RICPR  ali  44  3.............DKYSSNLVPVNIEDEMKVSYLDYAMSVIVSRAIPDVRDGLKPVHRRIIYSMYEAGNHASKPYRKSARIVGDVMGKYHPHGDSAIYDSLVRMAQDFSLRLPLVDGQGNFGSMDGDAAAAMRYTESRMAKVAHKLVEDIDKGTVSFNINYDGSEEEPSVLPAMFPNLLVNGSGGIAVGMATNIPPHNLGEIIDACCLYIDNHDIEILDLLEVVKGPDFPTGSMILGISGIRSAYLTGRGSIIMRGKAEIENVGNRQAIIITEIPYMVNKARLVEKIAEMVKEKRIEGISDLRDESNKNGIRIFIELKKDVVAEVVLNQIYACTQLQTNFGVIMLALKDGLPKVMNLKEVIAAFVSFREVVITNRTIYLLNKARDRAHILLGLTIAISNIDEIIYIIKASNDTNLAKQELMARQWFTEVQAKAILEMKLQRLTAMEKEKLEQDLKHLATDIAEYLNILASRTRLLEILKEELIKVKEEFASPRLTSI-EFGEFDQDIEDLIQREEMVVTVTLGGYIKRVPLSSYRSQKRGGKGRSGLSMRDEDITTQVFVGSTHTPMLFFSNIGKVYSLKLYKLPLSNPQGKGRPMVNILSLQENEHITNIMPLPENQDEWDHFATAKGNIRRSDLLDFKKIQSNGKIAIRLDEDDKLIDVKPCKEDEHILLATKAGKALRFPVESLRIKSRISDGVRGMKLAKEDSVISMTVLNSEEFILTVTENGFGKRSSAYGYRITDRGGSGIINMDINDKTGLVVGVMPVKMDDELMLITNSGKLIRCKLESVRITGRNTSGVILFKLDDDEKVVSVSLI........................ 882
150 0.000e+00UniRef50_A0A173V5U1 DNA gyrase subunit A n=39 Tax=root TaxID=1 RepID=A0A173V5U1_9FIRM  ali  41  2.....EEDYVMIPGSGTKKII-RDVKKEIETAFLDYSMSVIVSRALPDVRDGLKPVHRRILYTMHERGNDPSHAYRKSADTVGAVLGSYHPHGDASVYDAMVRLAQDFSLRYPLVDGQGNFGSVDGDPPAAYRYTEARMSRMAVEMLTDIEKDTIDWDPNFDETKKEPSVLPCRFPNLLVNGSQGIAVGMATNIPPHNLSEVIDGCIAYIDDPDIDLPGLMEHIKGPDFPTAGIIMGRSGIRAAYATGRGKITLRGRATIEETKGRTQIVITEIPYMVNKARLIEHMADLVKEKRIEGITGLNDETNRKGMRIVVDIRKDANAQVILNQLYQYTQLQDTVGVIMLAIDHKVPKVLTLKQMLQKYVEFQDEVVRRRTQYDLKKAKERAHILEGLKKATDIVDELIATIRACKGMAEAKAAIMEQFGFDDPQADAIVKLQLGRLAGLEXXXXXXXXXXXXXXXXXXXXXLADDARVLAIVKDELLEMKKRFGDERRTEIQS-VTGEVDIEDLIAEEQCVYTLTEAGYIKRQLKATYQAQRRGGRGISGMTRKEEDIVQEMFVGSTHDYVLFVTDRGRLFRIKGYTIAEGSRTSKGMNIVNLLQLAEGEKVTNMICQSEQSGGYVTMVTKQGLIKRTPLEQYANIRKSGLIGIALNEGDALAWTRLTSGHDMLIVATRNGQAIRFNEENARPMGRNGHGVRAIRLAEGDEVVGVCICREGGTVLTVTENGKGRRSDIDTYRITARGGKGIRNYDVS--RDKVAAVKIVDDVDDVLLSSQEGIIIRLHANEIPLQSRYGSGVRVMRLGENDKVMVLARTDHDDEAQTEKIDASEADAEPTAEQ 836
151 0.000e+00UniRef50_A0A0G4B141 DNA gyrase subunit A n=138 Tax=root TaxID=1 RepID=A0A0G4B141_9BACT  ali  41  66..........TIEESAYGKLKHTSIVNEMEKSYLDYAMSVIVSRALPDVRDGLKPVHRRILYSMFKSGIHWNTPYRKSARIVGDVLGRYHPHGDSAVYMALVRLAQEFSMRYPLIDGQGNFGSIDGDSPAAMRYTEARSAKITQELLADINKGTVDFIDNFDGSTKEPTVLPTRIPNFLLMGSEGIAVGMATKIPPHNLVETCNAITAMITKSDITHEELMEHIKGPDFPTAGIIYDQKSISEAYRTGRGRIVIRGKAAIEEKKDQFIIAITELPYQVNKARLLMKIADLVRDKKILGIRNLRDDSDRQGMQITIELKKDARPNVVLNKLFKYSELQSSFSLNMVALNEGTPLLMNLRQVLREYVIHRQLVVVRRSQNELKEARDRAHILEGLIIALNNLDDVIDTIRKSKDTPTAHDSLMKKFGLSDIQSTAILEMQLKRLAALERQKIEEEYAAIQEAIGTLIHLLNDPAKVLKKIAEETKEMVDLYGDERRTKIIKGKIGEFNEEDLIAEESTVITLTESGYIKRLSPDAFRSQSRGGKGSKGLNMKAEDVLKCIVTCNTHDNLFLFTNQGRVFEMKSYEIPDASRQAKGTAIVNILNLKSEEKVLSILVVDQDKDKFITLATKNGLVKKTALKLFNNIRQSGIVAIILNEGDELVWGKITTGMDHIMLITHDGKSIRFSEEEVKSSQRDTKGVKGITLKTGDSVIGVEVFEDENSLLLITENGMGKRTLLESYPLQKRSGLGVKVSEITKRTGKVAAAKMVSDNKEVVISTKLGKAIKMPISSIPTLTRPTQGVILMKMSDNDQVVAVALTIEDGDEENE............... 931
152 0.000e+00UniRef50_A0A2S0KNL3 DNA gyrase subunit A n=1 Tax=Fastidiosipila sanguinis TaxID=236753 RepID=A0A2S0KNL3_9FIRM  ali  42  11..KTEGISADELFETNVNNVIPVNLEGEMKQAFIDYAMSVITDRALPDVRDGLKPVHRRILYSMQTQSLTPDKPYRKSATVVGEVLGHYHPHGDSSVYDAMVRLAQDFSMRHTLVDGHGNFGSRDGDPAAAYRYTEARLTKLGVAMMESINKDTVDFKPNFDGHDMEPVVLPANFPNLLVNGSTGIAVGMATNIPAHNLGETINAAICLMKNPEASVSELMEHIKGPDFPTGGTILGTEGIKETYETGKGRIVVRAEAEIHKDNGRQEIIVKSLPYAVNKARLIEKIAEYVKEGKIEGISNIRDDSARDEVRIVIELKRDANAKLTLNQLYKYSKMQEAFNANMLALVPGKPELLTLRTALQYFLDHNRDVITRRIKFDLEKALARQHIVEGLRIAIDFIDEVIRIIRSSANEVEAKERLQERFDFSERQAQHIVDMRLGRLTALEXXXXXXXXXXXXXXXXXXXXXXXXXXXXTELRISELTEFKETFADDRRTVIDIYGIDGIADESLIKREDVVVVLTKFGYVKRTPISTYEVQHRGGIGVSGLSTREEDQVVDMFAVSTHDVLLVFTDKGRVFKLKGYDIPEGSRTARGTAIVNILQLEADEKVKKIINLPYDMSGTLFFATERGYVKRTNLEDFRNINKTGIIAIKLEDYDHLLNVEYLPEEDDVMLITKNGKGIRFDQNDVRIMGRSTRGVRGINLDNDDEVIAVVPLRNDNELLFVTEKGFGKKTYAQEFRAQSRGGKGLICYKASERTGGLVKASELYDFLDVIIMNQAGLIIRIPSAEIPNLGRYATGVHLMRVVKDDVLTYALVLKSDENDEVEGTELEDDLKESE... 861
153 0.000e+00UniRef50_A0A1V6FGT9 DNA gyrase subunit A n=6 Tax=PVC group TaxID=1783257 RepID=A0A1V6FGT9_9BACT  ali  40  1MSDDNSKNNLPPDELAAQNDIPFAIEDIMHRAYLQYSLSVNVGRAIPDVRDGLKVGNRRILYAMRQLGFTKSHSYSKCAKVVGDVIGNYHPHGDMAVYDTLVRMAQDFSMRCPLIDGQGNFGSIDGDPPAAYRYTECRMERLAEEMLADLDKDTVDMRPTFDEKMTEPVVLPARFPNLLVNGATGIGVGMATNIPPHNLGETIDATVAVIDNPLISIRELMRYLPGPDFPTGGSIQGIRSIIALYETGRGSVRLRGKAAIEERNGREQIIVTEIPFAVNKEALVLKIAELVNERRIVGISGIEDLSDRVGIRIVIDIKRGAIASVVLNQLYSMTPLETSMGAQFLVVDRGRPRTLNLKQVLEAYIDHREEVIIRRTQFELNKAEERDHIVQGLMIAQANIDEVVRIIRQSPNRDQASRVLIERFDLSDRQARAILEMRLYQLTNLAVDELRAEHEELLRRIGYLRELLANRNMIMDVVKNELLEVKAKYADPRRTMIVPQESELLME-DLIAREICVVPISASGYIKRVPADSYEAQNRGGKGVRGMRTKEEDYVEMLLTCCTHDIILFFTNKGLMHWLKAYELPEGGRDSQGKALVNLLQLQQDERVRAMIPVTDVEGLYIVMATRNGTVKKTELRAFKSMRRKGIIAITLVEGDDLIDAQLTDGQQEILLSSAHGMACRFLETDLRPTGRGAIGVRGMNTTPDSEIVAMSVVVPEDELLVITANGMGKRTPIGRYRLTRRGAKGVVSIKLRP-GDRVVAALQVDSDQEVLITSIQGQMVRLRVDDVRQTGRAAFGVIVMRLNEGDEVASATLV----DELSEEEIAANQAKKAELEE 895
154 0.000e+00UniRef50_A0A1V5UJI2 DNA gyrase subunit A n=6 Tax=Terrabacteria group TaxID=1783272 RepID=A0A1V5UJI2_9BACT  ali  47  1MAEDTNKKDMLEEEKIDSGTHPVDVVDEVRKSFLDYAMSVIVSRAIPDVRDGFKPVHRRIVYGMHEAGMTPDKPYKKCARIVGDVMGKYHPHGDQAIYSTLVRMAQPFSLRYPLVDGHGNFGSVDGDEAAAMRYTEARMEKLATEMVRDINLNTVDFGGNYDGSEKEPDVLPSRFPNLIVNGSDGIAVGMATYMVPHNLTETINAINLVAKNPDVTPREIMEKMHGPDFPTGASILGRKGILDYFETGEGSIIVRTKTHFETKGDRTWIVIDELPYKLNKATTIEQIAILVRNKEIDGIVDIRDESNKEGIRVVIELRRDVVPEVVLNNLLKQTRLQTSFKITNLCLVNKVPRILNMKELLVEYLNFQVEIIRRRTEHQLAQAEARDHVVEGLLKAIDNIDEIVTIIKNSDSGEDASQKLIERFNFSEIQTREVLGMTLRRLTGLEKDKLHNEREMLLANIENYRFILSAREHMVDVVLEELEEIKAKYGDKRMTEISD-DVADIDNEDLIPVEDVVVMLTNQGYIKRVDPEEFRMIKRGGVGVKGMRTKEEEIVDIILHTSTHTDILFFTSKGKVYRKRGYQIPQYRREGKGLPVINLLNIEKEEAVRAIVSTDYDEDHYLLYVTRNGVTKRTTLAEFARINVSGKIAIDLREDDELMDVKITDGTAIIGIGSSNGKMASFYETDVRAMGRTAAGVRGIRLDEGAYVVGVTTSLEGNLIFALTTKGYGKLTLADEYRLTKRGSKGVITIKESERTGTLAGIRAIKGDEDLFVTTESGMVIRTNFKEISMTSRNTMGVRVIRLRPDDVVSSFAVVEK...................... 823
155 0.000e+00UniRef50_A0A2D7A1C9 DNA gyrase subunit A n=1 Tax=Rickettsiales bacterium TaxID=2026788 RepID=A0A2D7A1C9_9RICK  ali  44  8..TDQEDLFEELPEXLEKGVSTXDIXXEMKSSYLXYAMSVIVGRALPDVRDGLKPVHRRILYSMYDSGYTATRPYKKCARIVGDVLGRYHPHGDTAVYDSLVRMAQDFSLRYPFIDGQGNYGSVDGDNAAAMRYTEARMAKISMSLLEDIEKETVDFGPNFDDSLEEPKVLPTRXPALXLNGTSGIAVGMATNIPPHNLNELXDGIXALIDXPDMEIXDLMEXVKGPDFPTAGIICGTEGXTKAYMTGRGSVVTRAKVSFEPKXGKXAIXVDELPYQVNXANLIVKIAELVQDKKXPGXXDLRDESDRKGMXIYIELKRDASRXVVLNQXFKHTQLQNSFGMNMVALVEGIPXLLXLKQILSYYILHRXDVVVRRTQFDLRKAKDXLHILEGXRIALDNIDEIIALIKASKDTDTARQGLIERFSLSEXQANAILEMRLQRLTGLEREKIENXXNEXXALIADXEDILAXESRVYQIIKDEQXXIRDXYGDERRSVIGD-PVHEMSMEDLIPNTQVAVLISKXGFVXRMPIDTFKSQNRGGRGIAGMSTXDEDSXEHLLITNTHDXLLCFTXKGRVFKIKSYXVPEASRXSKGISLAHFLHFDEDEELTSIIDVSFXTEEYLFMTTKKGVVKKTDIGAYVHFKNRPIAAINLDKGDRLQWVKKTTGKQDVLIVTSAGMVIRFXESQVRPMGRASRGIRGIKVREQDELVSMDIVEPTEEILIITKYGYGKNIRVNEFRCQNRGGXGVINFRKTXGDDEVKDAVIVSKDHEIMVVTEXGTICXQAVAKISTQRRSSMGVKIIKXDDGDKITAMKSIIEXEVXXXTXXATKAN........ 843
156 0.000e+00UniRef50_C7M9I4 DNA gyrase subunit A n=27 Tax=Bacteria TaxID=2 RepID=C7M9I4_CAPOD  ali  44  3...............EGEKLIPVDISDEMKSAYIDYSMSVIVSRALPDVRDGLKPVHRRVLYGMYDMGVLSNRPYKKSAAIVGEVLGKYHPHGDTAVYDTMVRMAQYWSLRYMLVDGQGNFGSMGGDPPAAMRYTEARMRKFSEEMLSDIDKETVDHQLTYDDSREEPIVLPTRIPNLLVNGSAGIAVGMATNMAPHNLNEVIDGTIAYIDNNDIEIDELIKYIKAPDFPTGGIIYGYEGVKEAFKTGRGRVIIRAKAEFQEIKGKDCIVVTEVPYQVDTSVLLKKTSDLVKEGRLEGITDVRDESARGKIRIVYILKRDAVPNVVLNNLFKHTELQTSFSVNNIALVKGRPQLLNLKDLIFHFVEHRYDVVYRRTDYELRKAKERIHILEGYMKVMATEDTMGKAIEIIRFHDKPKEDLIAEFDLTDVQAEAILALALRRINKVLXXXXXXXXXXXXXXXXXXXXXXXXXXXXTEIIKEELLEIKEKYGDERRSTI-EYAGGEFSVEDMIPDDKMVITISHAGYIKRTQLSEYKTQSRGGVGQKASTTRDQDFLEHLFVSSNHQYLLFFTQKGKCFWMRVYEIPEGSKTAKGRAIQNLINIESDDKIKAFVSVDYISNNYLIMATKKGIVKKTLLKEYSRPRQNGINAITIKEGDELIEAKLTSGSSQLMLAVKSGRAIRFAEDKVRAVGRNSQGVRGIDDTENDEVVGMIAIENEETVLVVSENGYGKRSYIDDYRITNRGGKGVKTISITEKTGQLVAIKSVLEGEDLMIINKSGIAIRLSIDTLRILGRATQGVKLINIKGKDSIAAVTKVMKEDDDESTEEAPTNDNEPLDTQE 841
157 0.000e+00UniRef50_A0A2A5DB89 DNA gyrase subunit A n=2 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2A5DB89_9BACT  ali  42  1MADETAPKDQPIPDTV--------IEKEMCESYLTYALSVIHDRALPDVRDGLKPSQRRILVAMNDLHLRPGAKYRKCAKIAGDTSGNYHPHGESVIYPTLVRMAQPFRLRHPLIDGQGNFGSIDGDPPAAMRYTEAKMTGPAEEMLTDLEKDTADLKSNYDETRMEPTVLPGKFPNLLVNGSEGIAVGMSTALPPHNLLEVLNAIRHLLDNPDCNVRDLMQIVTGPDFPTGGIICGRSGIAEAYLTGRGRVILRAKMHLEESGGRDALVITEIPYEREKAAIIEKIALEVKNERIEGIHDIRDESSREGMRLVIELRKDGDAVVVENLLYKHSSLQITYAIRNTALIEGQPRTLNLKELVAAYRDHRFDVIRRRTRFLLNKAEHRLHILEGMMIAIRSIDEVVEIIKASADTQAARQGLEAAFNLTPIQSQAIVDMRLGRLTGLEIEKLQTEIDGLKVDIAWFLRILAEDELVFNIIREDLDELEKKYAEPRRTAIGEGVMDFLTE-DLITEETMAVTVSSKGYVKRTSVDAYRAQSRGGRGIAGGKAKDGDVLSHLFVCSTHDYLLVITDRGRLYWLKVYRLPEQERTAKGRSIRNLIEIQPDEEIRSILSTRNFDEDYLVFATEKGKVKKTELKAYSNVRSAGIIATKLEEGDRLIGTRLVSKGNEVMLITAGGQVVRFREDDARAMGRNAAGVKGATLRGDDKVVDLITGTEEEYLLLVCENGYGKQTRIGEFRLTKRGSQGVVGIKTNERNGQVVNARNASRCDEVIFSTTGGMLVRTKIDEISKQGRATQGVRLVNLKDGDKIASLAAIPREEESDSKTEEK........... 823
158 0.000e+00UniRef50_E4XU22 Uncharacterized protein n=1 Tax=Oikopleura dioica TaxID=34765 RepID=E4XU22_OIKDI  ali  41  1..............MSNDSIKPINVAEELSQSFLEYSMSVIISRALPDVRDGLKPSQRRVLYAMRQLGVTPGKAHVKCAKIVGETMGNFHPHGDQSIYSTLVNMGQPWSMREMLVDGQGNFGSVEGDAAASMRYTEARLHPLGMAMMEDLEKATVDFQPNYDGSQEEPTVLPSAFPNFLVNGGTGIAVGMATNLAPHNLGEVIDGICAQIDKPDITLPELMQYIKGPDFPVSCEIRGIRGIEEYFRTGRGSMRLRGKVEIEENENGKSIVIREVPYGVNRAVLQERIAELVNEKTLTGISGMRDLSDEE-TRIEIELKRDARPQVVVAQLFKLTALETSFSVNMLAIHQNRPKQLSLKEAIDAYIEHRRDVIIRRTRFLLGKAEERAELLEAFLLALGHLDDFIRIIRDSKNRDEARELQGDRYVFSERQVNAILELRLYQLTGMEQDKVKGEYDGILIEIKDLLDILAREVRVLTIIKDELRVIRDKYATPRKCPILA-EAGEVAMEDLIANDAMIVTLSHRGYVKRTPATEYRLQGRGGKGLKGMETKADDFVEHLFSVQAHDYLLFFTNTGRVYVERVFELPEGSRTSTGRSIKNVLNLKPDEKIAALLRLERTTDDFVFFATRNGKVKKTALNDFRNYRKDGIIAINLDEGNDLIGVSLTSGEDEIVLVTRDGMSIKFTEPQIRPQGRATAGVTGIRLRKDDYVVGMAIVSEETMLLVASENGLGKRTAFSSYRPLRRGGLGVKTLNVTDKTGKVVNAVSVTEQDELMLMTSTGQSIRIRVNEIRETGRVAQGVKLLTLKEGEKLQDISLVIPDGEDDAGSSDATTAEDAG.... 840
159 0.000e+00UniRef50_A0A1M6B6F9 DNA gyrase subunit A n=2 Tax=Maribius TaxID=387095 RepID=A0A1M6B6F9_9RHOB  ali  40  1MSDRPDPPKDIDENGPEGPGPSIDIVDEMQASFLDYAMSVIVSRAIPDLRDGLKPVHRRILYAMHETGNTFDKPYRKSARPVGDVMGQYHPHGDSAIYEALVRMAQDFSMSLPLLDGQGNFGSMDGDSAAAMRYTEVRMDKPARALLTDIEKETVDFQDNYDGKQLEPTVLPARFPNMLVNGAGGIAVGMATNIPPHNLGEVVDATLALIEDPDLSSERIMEIIPGPDFPTGGIMLGRSGARKAYLEGRGSVILRAKTRVEEIKDRFAIVLDEIPYQVNKAALVERIADLVKEKKLEGISAVQDESDRVGVRVVVELKKDATPDVVLNQLFRFTPMQTSFGCNMLALHGGRPEQLTLRDFLTHFITFREDVVARRTAYELRKARERSHILCGYAVAVSNVDEVVATIRASADAPEARIKLMERRWLSEAQARAILELRLQRLTQLGVKEVTDELEELAGKIKDYLDILRSRDRIMGIIADELREVREDFAVPRRTEIVDW-SGDMEDEDLIEREEMVVTVTQSGYIKRTALADFRAQRRGGKGVSGGALKDDDVVTTLFVANTHTPLLFFTTDGMAYKLKTWRLPLGGRTSKGKAIVNILPIPQGVSIAAIMPVDRDEDHWDDFATSAGTVRRNKLSDFTNVNRAGKIAMKFEGEDELINARIASPDDDVMLVTAQGRAIRFPSTDVRVFSRSSLGVRGIRLADGDEVVSMAVIRHEDLILTITAGGSGKLSSSHDYPVRGRGGQGVMAMDKAMRGGPLLASFPVEMDDQIMLATSKGQSIRVPVDGISFRSRAAGGVRVFNTGAGEEVVSVAWIADQSDAEADAEGGTTDETGES... 925
160 0.000e+00UniRef50_D4Z2Y3 DNA gyrase subunit A n=40 Tax=cellular organisms TaxID=131567 RepID=D4Z2Y3_SPHJU  ali  42  1.......MTDETALADPSDISPISIVEEMKASYLDYAMSVIVARALPDVRDGLKPVHRRILFSAHESGFTHNKPYRKSARIVGDVIGKYHPHGDSAIYHALARMTQDWSMRVPLIDGQGNFGSMDPDPPAAMRYTEARLAKVTNALLDDLDKDTVDFQPNYDASESEPQVLPARFPNLLVNGAGGIAVGMATNIPPHNLGEVIRACLAYIDNTGITIDELIQIVPGPDFPTAPLILGQSGARSAYHTGRGSIMMRARHEIEERGDRRSIVLTAIPYQVGKNGLVEKIAEAAKDKRIEGISDIRDESSREGVRIVMDLKRDATPEVVLNQLWRNTPAQSSFPANMLAIRGGRPELLNIRDIIEAFVRFREEVITRRTKYELNKARDRAHILLGLVIAVTNLDEVVRIIRGSASPAEARETLLARDWLSDTQVRAILDLRLHRLTALGRDEIGNELAELAAAIAEYLAILGDRVKLYAVMREEFEAIERDFATPRLSEITA-AADGIDDEDLIEREEMVVTVTVQGYIKRTPLESFRAQARGGKGRSGMTTKDEDAITELFVTSTHTPVLFFSTAGKVYRLKVWRLPEGGPATRGRPMVNLLPLSPGETIQTVLPLPEWKDLHVMFATANGTVRRNSMDAFANIPSNGKIAMRFDDDDRLIGVALLTEEDDVLLATRQGKAIRFQATDVREQSRTSTGVRGMTLKKDDEVISLSILHKEQFILTVCANGYGKLSSAYDYRRTGRGGQGITNIDNIGRNGPVVASFPARHGDHLMLVTDQAKLIRMGLESLRVIGRSSAGVRLFNVSDDEHVVSAAKIEESDEETEVSTPAGLEVSPEASPE 902
161 0.000e+00UniRef50_D1JED8 DNA gyrase subunit A n=1 Tax=uncultured archaeon TaxID=115547 RepID=D1JED8_9ARCH  ali  42  3........EDQREAEVRERVIEVSVEDEMTHSYMDYAMSVIVGRALPDARDGLKPVHRRILYGMHELGVTHNRPHKKSARIVGDVLGKYHPHGDVAVYDTMVRMAQDFSYRYPLVDGQGNFGSVDGDAAAAMRYTEARLSKIAGELLVDLEKDTVEWSPNFDNSLKEPQILPAKLPNLLINGSSGIAVGMATNMPPHNLTEVVDGVIRVIEEPEVSIEELMQIIKAPDFPTGGIIIGYEGIKRAYETGRGSIRIRAKAEIEVKGKKERIVINEIPYQVNKSRLVEEIAEFAKKYKVESISGLRDESDRKGMRIVIELKAGANSAIILNRLYKHTQLENTFGVINLALIDGEPRVLTLKELIECYIKHRKEVTIRRLQYELERAEKRLHILKGLIIAISNIDEVIRLIKAASDTKTAKSALIARFELSEEQAKEILDMRLSRLSALERDKIETERAELETKINWLKEVLGSEARIYELLKEDLIEQKDKYGDARRTNIEEMVT--LSERDFVEEKEVILYLTQRDYVKRLPADIFKQQMRGGKGIAVIEKKEDDKIVNFIRASTRERLIFFTEFGKAYQVKTYEIPPSSRHSKGKPLVNIPGTEEREKFVTAVAIPEEVDKYLVFATKRGVVKRSSLAKLKAIRSTGVVAVRTTKGDSLADVVLIKPSLDIILSSKNGKAIFFHEEELREMGRYAAGVRGMRLEKDDEIASVEVSKEKSRAVTITEKGYGKRTKLDAYRETHRGGKGVISIKTGERNGKVVCIKQVKNTDELMVATSDGMVTKISVRSISVQGRNTQGVRIMNVKKGERVVAVDILSATES................... 840
162 0.000e+00UniRef50_A0A0G0N5K3 DNA gyrase subunit A n=10 Tax=Patescibacteria group TaxID=1783273 RepID=A0A0G0N5K3_9BACT  ali  41  1..............MNIGKIRQVEITEEVQKSYLNYAMSVIVARALPDVRDGLKPVHRRILYAMHQMGLSAGSHYTKSAKIVGETMGKFHPHGDGPIYDALVRLAQDFSMRYPLVDGQGNFGSVDGDPAAAMRYTEAKPAKISQELLGDIEKDTVEFIENFDGTLNEPIFLPASLPNLLLMGSEGIAVGMATKIPPHNLREVVDAVVATIKKPPATDFDLLKYVKGPDFPTGGLIYGGKNLPEVYGTGRGTVIVRGVAKIEEERGKSRIVISELPYQVNKSILVAKIAELVRDKKIQGISDLRDESDRRGMSVVIELKKDARPKAVLNNLYKHTSLQTTFPANFVALIDGTPKTLALKQILVEYVKHRQRVVTRRSIYELTEAKRRGHILEGLKIALDNLDEVIKTIRQSKNSDVAKENLMSKFGLTELQATAILDMQLRRLSALEXXXXXXXXXXXXXXXXXXXXXLMHPEKILTIITNEVGALKEKFGDERKTKVYAQPVGEISEQDLIAKEETIITLTKTGYVKRVPISTYRAQRRGGKGVVGMTTKEEDEIAHILSASTHDQIMFFTDHGCVFSIKAWEIAETSRQSKGQAIVNLINIDQGETIQAVLPVESQEGKYLMMATRGGTVKKTPLSAFKNIRSSGLIAIRLEKGDSLAWVRPTSGEDHVLMATRKGQSIKFKETDIRGVGRNTQGVRGVRLTTDDEVISMEIIPSKSDILVVTENGLGKRTPVSNFPLQKRGGSGVKIAQISDKTGKLSSALMVTQDDQVIITSRSGQVIKLPLKNIPKLGRATQGVILMRFPKNDSVAAVALLDKDVAENKETSEVDEA........ 888
163 0.000e+00UniRef50_UPI000A069FB0 DNA gyrase subunit A n=2 Tax=Planctomycetaceae TaxID=126 RepID=UPI000A069FB0  ali  40  60..................RMIDLPIEDELRESYLTYAMSVIVSRALPDVRDGLKPSQRRILVAMNDLNLGPGAKRVKCAKISGDTSGNYHPHGESVIYPTLVRMAQEWNLRSLLIDKQGNFGSIAGLPPAAMRYTEARLSAVAATMLDDLKLDTVDYIPTYDEVRTEPTVLPSKFPNLLVNGSGGIAVGMATSIPPHNPSEVCEALIGLLDNPDMSIAEIMAVMPGPDFPTGGIICGRAGIIRGYKTGRSTIQVRARCRVEEMKGNRSIIVTEIPYQQYRDRVIEKIAALVNGDRIKGISAIRDESDKEPVRLVIELKRDADPDVVLNQLYQFSPLQDSFSLILLALVDGKPRELTIKEMLQEFIRHRATVIRRRTQFLLARARRRKHTVEGLLLALANIDEIIQTIRTSRTQPEAKQRLMDSYTLTSVQTDAILRMTLGQLVNLEQEKLSGEHAQLLVEISEYLEILGDQQKIYDIIKSDLEEIQRRFGDKRRTEISTEEVGSIDLEDLITEETMVVSISHRGYIKRTPTTTYRAQRRGGKGLKGAKTEDEDPIEHLFVASTHAYLLFFTTAGKVYWQKVYDLPQLARESRGRAIVNLLNLAEDEQIAECLAIRDFPGHFIMMATRDGLVKKTSLESYSRPKRGGIIAIKLREQDKLVDAAVVGPGTEVVLVTSSGMAIRFPESDARSMGRNTSGVKGINLSKDDSIVGMVVADPDATLLTVCEKGYGKRTPFARYRTQKRGGKGLRDIRTSERNGNVVDIVRVNDEDEILMMTAKGKIQRIAAKEISVIGRNTQGVRIMSLGDDDTLVAVVRVPAEENGIEETDVID.......... 922
164 0.000e+00UniRef50_A0A096AHK5 DNA gyrase subunit A n=26 Tax=root TaxID=1 RepID=A0A096AHK5_9MICC  ali  40  1MSENNTPDPDVNAEGAGDRVSQVDLQTEMQQSYLDYAMAVIVGRALPDVRDGLKPVHRRVIYAMYDGGYRPDRGFNKCARVVGEVMGHFHPHGDSAIYDTLVRLTQDWVMRYPLATGQGNFGSPGNDGAAAPRYTETKMAPLAMEMVRDIHEDTVDFMPNYDGKNQEPTVLPARFPNLLANGSAGIAVGMATNIPPHNMRELADGVQWALQHPDASREELMQRIQGPDFPTGARILGRKGIEDMYRTGRGSIPMRAVVNVEEIDGRTCLVVTELPYQANPDNLAIKIADLVKDHKIQGIADLRDESGRTGQRLVIVLKRDAVPKVVLNNLYKHTELQQNFSANMLALVDGVPRTLSLDAFIIHWINHQIDVIVRRTKHRLKKAKALAHIQVALLMALDVLDDVIALIRKSPTVDESREGLKKLLGIDDDQANAILDMQLRRLAALEXXXXXXXXXXXXXXXXXXXXXLASETLQREVISEELTDIVERFGDDRRTEIVRGYDGDMSVEDLIPVEEMVVTITQGGYVKRTRSDNYRAQNRGGKGIRGAQLRGQDVVEHFFVTTTHHWIAFFTNFGRVYRLKCYELAEAARDARGQHVANVLAFQPGEQIQQVLALENYQSPYLVLATRNGLVKKTRLEEYDTNRTAGVIAVNLREGDELVSAGLASEHDDLMLVSKKGMSVRFTATDLRPMGRATSGVTGMKFRAGDELLGMSVVRDDEFVFTVTDSGYAKRSPVSDYRVQGRGGLGIKVANLPEDRGELVGFKVVQEDDEILVVMQSGKVVRTAVNQVSPTGRDTMGVIFAKPDKKDHILAVAKNANHDGEEAGDDETDTSGVDVEGTE 863
165 0.000e+00UniRef50_A0A2D5AT46 DNA gyrase subunit A n=3 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2D5AT46_9BACT  ali  39  1MSDTNRPPTEIPPTPPGGLIEPRLIEHEMSESYLNYALSVIHSRALPDVRDGLKPSQRRILVAMNVLKLRPNAKYRKCANIAGVTSGEYHPHGESVIYPTLVRMAQRFSLRYPLLDGQGNFGSIDGDPPAAMRYTEARMAGPAMEMMADLDKETVDYQPNYDERLLEPVVLTSRFPNLLCNGSDGIAVGMATSLPPHNLHEIAKAIRAVLHSAQTTLAELCQIVKGPDFPTGGIIMGRSGMLRAYTSGRGRVIVRAKHHVEDVRTKEQLVFTEIPYQVRKTTIIEKIVELVRENRVTGIADLRDESDRDGIRLVVELKKNEDPQVIVNQLFQYTPLQTTYSIINLAIANGRPKTLTLRGLIDAYIEHRRTVIRRRTQFLLRKSEERKHIVEGLRIAIGEIDEVIKIVRGAPDTETAKHGLISRFSLSLAQAQAIVDMRLGRLTGLEXXXXXXXXXXXXXXXXXXXXXLNRDERVVAIILEDIDEIEQRFGDERRTEIVEEVDGGFDIEELITEEMMVVTFSRSGYVKRVGLDEYRAQGRGGRGVRGSVTREGDVLRSIFVANTHDYILCFSNTGRVYWLKVYQLPEGSRTSQGRAMRNLLPIEGEEEIHTVLRVRSFDDESVFFATRKGTVKKTRLEAFSRPRSGGIWAIQLDEDDRLVGVGLAKPGDTILLATATGKAIRFDESAARAMGRQAHGVRGIKLVGDDKVVGMFVADPEDTVFTACEHGHGKRTPLEDYPIRNRGGQGVINIRTEGRNGRVVGFDLAGDGDEVLFITESGMIVRSSMAGIRPMGRSTQGVRLINLKSEDKLVGAEIIQAEDLEIPEDEVADGPKALASVS. 843
166 0.000e+00UniRef50_A0A239RGE5 DNA gyrase subunit A n=2 Tax=Bacteria TaxID=2 RepID=A0A239RGE5_9FIRM  ali  42  1MSDDDK-----IFDKPHDDVKEVDLKKTMENSYIDYAMSVIASRALPDVRDGLKPVQRRILYSMIELNNGPDKPHRKCARIVGDTMGKYHPHGDSSIYDALVKLAQDWNTRYPLVDGHGNFGSMDGDGAAAMRYTEARLTKISMEMLADINKDTVDFIPNFDETEKEPVVLPSRYPNLLVNGTSGIAVGMATNIPPHNLREVVGAVVRIIDNRETDIEEIMDIVKGPDFPTGAEILGRRGIEEAYRTGRGKIKVRAISEIEPMKGKQRIVITQLPYMVNKALLIQKIADLVKNKKVEGITDLRDESSREGMRIVIELRHDVNANLLLNNLYKHTQLEDTFGVNMLALVDNQPRVLPLPDMLKYYIRHQEDVVTRRTKFELNAAEKRAHIVEGLLIAIDNIDEVIKIIRAAANVNEAKVKLMERFNLTDAQAQAIVDMRLRALTGLEXXXXXXXXXXXXXXXXXXXXXLADEKMLLSVIRDEMQIIADKYGDDRRT-IIGQAVEDFTDEDLIDDEPAVLTMTHFGYVKRMSVDNFHAQNRGGKGIRGIQTIEDDFIEDLLMTTTLNNILFFTNKGRAFRLKTYQIPEAGRNARGVAMVNLLQLEAGEHVSAVVPIREFENKYFIMVTKKGLIKKTPQMDFKNIRKNGIIGISLREDDELIEVKTTDNTRDIFMVTKNGMCIRFKDTDIRSTGRSSMGVIGMNLEHGDEIVGMQMNTQGEKLLIVTEKGMGKKTDIAEFHVQRRGGKGLKCYKITEKTGNVMGVKAVNDNHEIMMITTEGIIIQLRCDEISTYSRVTSGVKLINIKEGVTVAQIAKVRDEDDVVEETIDDSDNKEESTSVE 849
167 0.000e+00UniRef50_A0A2D6UHL7 DNA gyrase subunit A n=12 Tax=Verrucomicrobia TaxID=74201 RepID=A0A2D6UHL7_9BACT  ali  42  76.................ERLIPTNITEVMQTAYIDYSMSVIISRALPDARDGFKPVQRRILYAMLREGLVHNRNFDKCAGVVGEVLKNYHPHGDASVYDTLVRLAQPWVMRYPLIEGQGNFGSIDGDPPAAYRYTECRLFSIAEEMIRNIDEDTVDFVPNYKESTTEPSVLPAAVPNLLINGSTGIAVGMTTNIPPHNLSEVIDATCAIIDNPAITIDEIIEIIPGPDFPTGGTVAGKREIEKYMKTGRGILKTRGTCEIEELNDKEQIIITETPYNVNRATLVTKIAALVNEKLIEGVSDLRDESDEN-TRIVIELKRGEIPRVIINQLYKMTQLESSFGVILLALDKRRPKQMNIKELIGCYIEHRREVIFRRTQFQLKKAEDRAHILEGYLLALDNMDEIVRIIRASQSRDDARSRLMEKFPFSERQTNAILDLRLYQLTGLEXXXXXXXXXXXXXXXXXXXXXLENEGELLGVIKTELRTIQDKYGTARRSAISE-QEGTLSMEDLIPREACLITVTHKGFIKRTSLDEFRAQKRGGVGVKGAGQYEDDFIEHIFSASTHDFILFFMNNGRMYVQKVYDIPEGSRISKGRAINNLLEIQKGEKVAAMICVEAFEEDRLVFCTKKGVVKKTSLYDYRNFRRMGTKGINIDEDDELLTVRRTNGDDTLIIVTRTGQSVRFHEDDLRTQGRATRGVIGIRFKGKDEVKAMVVVNPESTLLIAGTNGMGKRTEFEEYRIQKRGGTGIIAMKTRA----VTGALNVTDDDEIMMLTKSGQAVRSPVRDVRVIGRTTQGVRLINLRDGDRLIGISKVKDEDIEETDSPEGAEETAPE.... 893
168 0.000e+00UniRef50_M4ZVR9 DNA gyrase subunit A n=42 Tax=Bacteria TaxID=2 RepID=M4ZVR9_9ACTN  ali  43  18....EPPASGGDDGTPDDPIQPIPLSDEMESSFLEYAMSVIMSRALPDVRDGLKPVHRRIIWDMEEQGFRPDRPHVKCARVSGDTMARFHPHGDSAIYAALVRMAQPFSLRHPLIDFHGNYGSPDF-GPAASRYTECRLHPLAMQLLADIDEDTVDMIPNYDGTTEEPLVLPSRFPNLLVNGSQGIAVGMATNIPPHNLGEVIDAVVHLIDHPDATVEDMIEHVKGPDFPTGAYILGRSGILDAYRTGRGSVKTRAKASIEETKGRYEIVVTELPYQTSVSSIAARIDELVTAGDLEGISDVNDDSSGGETSLIISLKRDGNPNVILNKLYKMTQLQSSFSINMVALVDGVPRQITLLDALTAYLRHQVDVITRRTEFRLAKAERREHILEGRIKALNVIDEIIALIRASDDVATAREGLMEPFEFSEVQANDILDMQLRQLTRLSRIDLETELDDIRASIEDLQDILARPERLNGVIKDEILAIKEEFATPRICEI-TYDDGEMSIEDLVDDKELVIVMTQAQYVKAVPAASFKTQGRGGRGVSGGKLKVDDIVRHVIFTTAHAHLLFFSNRGKVYRLRALDIPERERTAKGMPMVNLLPLQADEKIQAIIDTREFADRYLFFATEQGTVKKTTFGAYDTSRRDGLIAINLKDDDRLMKVIETTGDDDIFMVTKRGMTIRFNENDVRSMGRTAGGVRGIKLKNAQDVVSVDVARDDTSILMVTESGYGKRTELDQFNVQGRGGQGVIGIKLTGKKGEVVDAFMVGLDDDIVAVSKSGITIRMPVREISTQGRTATGVKVMNMDDGDIVGSVAPILATDAEIDDGE............. 841
169 0.000e+00UniRef50_A0A271IZQ2 DNA gyrase subunit A n=6 Tax=Bacteria TaxID=2 RepID=A0A271IZQ2_9BACT  ali  44  5.............PDSASRIIPINIEEEMKSSYIDYSMSVIVSRALPDVRDGLKPVQRRVLYGMQELGLAAGRAHKKSARIVGEVLGKYHPHGDQSVYDALVRMAQDFNVRGPLVDGQGNFGSIDGDSAAAMRYTEARLTRLSEELLRDLDKETVDYTPNFDGSLNEPSVLPAALPNLLLNGASGIAVGMATNIPPHNLGELVDGIVAYIEDPEVELDVLMEHIPAPDFPTGGVIYGVGGVREAYRTGRGRVVMRAKMHEEEIKGREALVVTEIPYQVNKSTLIEKIAHAVRDKKVDGIADLRDESDRDGMRIVMELRRDAVPEVTKNQLFKYTQLQQTFGMNMIALVGGRPKTLGLKDMIRHYVDHRHEIVVRRTEFELRKAEERAHILEGLTIALDHLDAVISIIRHSADTDAAKVNLMRGPWLSSAQADAILALRLSRLTGLERDKIAAEYRDILQEVERLQAILASRDLRMQIIADELREVAEKYADPRRTEIDIMGGGDIDLEDLIEDEHVVVTITNQGLIKRTAIDEYRSQNRGGTGHRGTGTRDEDFVEHLFTAGAHDYLLFFTDHGQCYWLRVYNVPEGSRTAKGRSIRNLIQIDAEDRVRAVIDDDFLENHFVTMATKQGLVKKTALSAFKRPLVTGIIAIDIVDGDQLIEAHLTDGGTEILLGSSEGQAIRFHESDVRSMGRKSRGVRGMKLPDGEQIVGMIAVRRDGQVLTISQNGFGKRTPVETFRLQSRGGKGVLAQKTTAKTGPLVALKSVLDDDQLMIATEAGIMIRMAVSDISTYGRNTQGVRILRLKDHDAIADVARVVIEDEEDVAILATDGDAVPTE... 901
170 0.000e+00UniRef50_A0A2V2D7D8 DNA gyrase subunit A n=1 Tax=Ruminococcaceae bacterium TaxID=1898205 RepID=A0A2V2D7D8_9FIRM  ali  43  3........ENLDLEFKNQKILDVHMEKEVKTSFIQYAMSVIVSRALPDVRDGLKPVHRRIIYAMYEDKITHDKAFYKSATTVGNVLGRYHPHGDSAVYESMVRLAQPFSLRYPLIEGHGNFGNIDGDKAAAYRYTEARLARLADEMTRDIEKDVVDFCNNFDNKRKEPTVLPSRIPNLLVNGSMGIAVGMATNIPPHNLCEVIDGTIFLMENPNATVSDLMNYIKGPDFPTGAIICGTAGIYEAYQTGRGKVTVRARVEVDDEKR--RIIVTEIPYGVNKSNLVESIADCVKDKKIEGITAIRDESGRAGLRIVIEFKRDANGQVILNKLYKYTQLQDTCAINMLAIADNVPKLLGLKEILNYYIAHQENVITRRFNFELDKALKELHLNEGYKIAADNIDEVIKIIRGSESIQNSKENLIERFGLSDAQAQAIVEMTLGRLSGLERQKVLDKIAKLSEQVAEIRGILSSENGIKNVIKEELLQIKQKFGDARKTELAP-VENEIIMEDLIERHTCIITMTNSGYIKRQPSDVYSAQHRGGKGIIGMTAKEEDFVEQVSAVNSHSYLLMFTNRGRVNVRKAYTIPESGRTTKGTNIVNIIELEENEKVTALVSSEDFSDKKYTMVTKRGVIKRTRLSEFEMRRKGGKIAISLDDNDDLIYVGLTDEESRIVLATKNGFAVKFRLGDIRELGRTARGVRAIKLSDDDEVAGAAVEEDDKYLLTITENGYGKRTEFGEYNLHNRGGKGVHCHNTV-RTGKIAGIAAVTADEDVMIITNVGTIIRVPVTDIPVYGRAAGGVIIMRQTGESKIVNFTCIAENKEKENTDDNEIENKKSDS... 827
171 0.000e+00UniRef50_A0A133YGM6 DNA gyrase subunit A n=1 Tax=Clostridiales bacterium KA00274 TaxID=1497955 RepID=A0A133YGM6_9FIRM  ali  43  11..KAQELQIEQTFRDNLTNVVPVNLEEEMRKSFIDYAMSVISDRALPDVRDGLKPVHRRILYSMFTQGYTSDKSYRKSASTVGDVISRFHPHGDAAVYDAMVRLAQDFSMRYMLVDSHGNFGSRDGDPPAAYRYTEARMAKLAETMMQDINKSTVDFRPNFDDHHVEPVVLPTNFPNILVNGSVGIAVGMATNIPPHNMRETIQAAIYLMEHPEADVDELMQFIKGPDFPTAGIILGTSGIKETYRTGHGRIVVRANAEIIDTVPA-RIVVHDLPYMVNKARMLEKISELVKAKRIVGISAIRDESDRNEVRIVFELKKDANPLVTLNQLYANSQMQEAFNAHMLALVPNKPELLTLKSALQYYVDHQRQVIYRRTQFNLEKAELRQHILEGLKIAVANIDEIIRIIRSSKSENDAKLNLQARFNFSDRQAQHIVDMRLGRLSGLEVENLYAEYDEISAKIATYHDILDNPPVLDNVLKTEITAVMEQYGDDRRTEIDPYGVDGIDDESLIKEETVLINLTKQGYIKRLTPDTYNMQHRGGKGVSGMTIKEEDCIHKMITASTHDDILFFSNLGKVYRLRAYAIHEASRTAKGMAIVNLLQLDANEKIVEILAVPEAEEKRSLIVTKQGLIKKTKLSEFKNINKNGKIAFALRDGDELVAGALATADATIFMVSHDGMAMRFLSSDVRPIGRKSYGVRGIKLRDGDYLIGVVVEQSGEDLFLLTEAGYGKRSHYADFRLAKRGGMGVKAYNCTDKTGKVLAVCSLSGDYDIIMINDSGMTIRISSQEINVQGRNTQGLRLMR--SNDKLAALAKVEHADEEASSDSDTEDSEVDEAEN. 850
172 0.000e+00UniRef50_G7I9Z9 DNA gyrase subunit A n=23 Tax=Pentapetalae TaxID=1437201 RepID=G7I9Z9_MEDTR  ali  38  80.....DNGSSDVVKRSEGRIVLTELHKEATEAYMAYAMSVLLGRALPDVRDGLKPVHRRILFAMHELGLSSKKPFKKCARVVGEVLGKFHPHGDTAVYDSMVRMAQDFSLRSPLVNGHGNFGSIDADPPAAMRYTECRLEELAEAMLADLDQDTVDFVPNFDNSQKEPSLLPARLPTLLLNGSSGIAVGMATNIPPHNLGEVVDVLRVMIHNPEATLQELLEYMPGPDFPTGGLIMGNLGILEAYRTGRGRVVVRGKTDVESKSKRSAIIIKEIPYQTNKSALVEKIADLVENKSLDGISDIRDESDRSGMRVVIELKRGSDPLIVLNNLYRLTSLQSTFSCNMVGILNGKPKQMGLKEILQAFLDFRCSVVERRARFQLSKAQQRRHIVEGILVGFDNLDGVIRIIREASSNSIAAAGLQNEFNISEKQAEALLDMSLRRLTLRESDNFVAENKSLSEQISKLEELLSSRKNILEVIEQEAIDLKNKFASPRRSILEDTDDGQLEDIDVIPNEEMLLTLSEKGYLKRMKPSTFNLQHRGTIGKSVGKLKMNDSMSDFIVCRAHDFVLYFSDKGTVYSARAYKIPECSRTASGTPLVQILSLSDGERITSIIPVSEFTDDQFLMLTMQGYIKRVPLNSFSSIRSSGIIAIQLVPGDELKWVRCCTNDDFVAMASHNGMVILSLCSKIRTLGRNTRGALAMRLKEGDRMASVDIIPDGPWLLFISESGHGKRVPLSRFRMSSLNRVGLIGYKFSAE-DRLAAVFVVESDEQVVLVSQSGTVNRIKVRDISIQSRFARGVILMRLDHAGKIQTASLISATECEPEEELAIAQG........ 938
173 0.000e+00UniRef50_A0A202DRV6 DNA gyrase subunit A n=5 Tax=unclassified Bacteria TaxID=2323 RepID=A0A202DRV6_9BACT  ali  41  2...EPSEAEVIVPQTHSREMELHTVEDVMEDNYLRYSMSVIVARALPDVRDGLKPVHRRILYTMLEEGIRPGGKYRKSANVTGTVMARYHPHGNVAIYDAMVRLAQDWAMRYPLVDGQGNFGSMDGDPPAAERYTEARLARTAEELLNDIEKDTVEFRDTYDGERKEPAVLPAKLPNLLLNGQVGIAVGMATNIPPHNLSEIVDAIVHLIDNPNASLDDLLEFVKGPDFPTGGVVYGKESIRTAFATGRGGVVVRGVASIEEKKGQQQIIISEIPYGVNKAGLLEKIADLYKEKKISGIRDLRDETARGIVRVVIDLKKDAYPKKLLNQLYKLTPLQLSIHYNMLALIDGQPRVLGLQDILNEYIKHRQVVVRRRTEFELKTAKARAHVLEGLKIALDHIDEVIKTIRGSQTTEEAQENLIKKFKLSEIQAQAILAMQLRRLAGLERQKVEDELAELLKLIGKLEKILASEQEILKIIKTELLELKEQFGDERRTKIVAQELGKLSDEDLVPDEQVVVTLTSANYIKRSSIADYKRQGRGGKGRRGMTTRDEDVIEHVVNASTHDYLLFFTNKGRVFRIKTYEVPAVGLNAKGVALVNLLQLQPEEIVSSVINVKQNAGGNLLMCTVRGVVKKTPFEQYQNVRTSGLIAINLDEGDELKWIRMTNGENEVIISTSQGQAIRFHEKDARPMGRVSRGVRGIRLRAGDQVIGMDIVEDDSFVFVISEFGYGKRTKVSQFTAHKRGGVGIRSAVVNKKTGPLIGVKTLTGNDEVIIISTAGQTIRLGLKDIPALGRATQGVRIMRLNDGDSVASLALVEKVDEEEEAEEINQPAEKPASK.. 866
174 0.000e+00UniRef50_A7I8T9 DNA gyrase subunit A n=1 Tax=Methanoregula boonei (strain DSM 21154 / JCM 14090 / 6A8) TaxID=456442 RepID=A7I8T9_METB6  ali  40  6.........PPAGTPETHKTEPISIEQEMKTSFINYAMSVIIQRAIPDVRDGLKPVHRRSLYAMWDMGNTSDKPTKKSARVVGDVMGKYHPHGDASIYDTIVKMAQPFSYRHPLVQGQGNFGSVDGDAAAASRYTEVRLFPYAEALLEDLDKETVEFVPNYDESLKEPTVLPSKIPNLLVNGTDGIAVGMATKMPPHNLREVCAAVNRFLDEPSVPVEELLKIMPGPDFPTGGILMGVDGVKNIYATGQGRIVVRGVAEIEESEGGNRIIVTELPYQVNKAQWITAIADMVKDKKLDGISDIRDESDKDGIRVVFELRKGTISAVILNNLYRFTALESGFSAYNLAIVDGTPKLLNLPALLGNFVHHRIEVIRRRSEFDLKKCQERVHILNGLLTALASIDKIIAAIRGSDTVDNARIALISGFGLDELQANAILQMQLRRLAALEQQKIVDEKSTLEAEILKLETILASEENIKDEIRRETSEIALKFGDARRTEI-TLDASDLSTEDLIEDKTVLVSITTANYIKRMDLDTYRKQRRGGHGITGMTTKEDDVVSSVFAAGMKDYLLCFTNIGRVYWLKVYQIPESSRIAKGKPIVNLLNLKDEVVTTVIPIREFRKDRYLLFATQLGQVIKIPQDEFSFPRSTGTNAIRLRENDKLVDVITTDNTKEVVLSTRFGYGLRFHEDTVRIVGRGASGVIGMRLRGNDTIVALTLVEKD-HLLSITDAGFGKRTEFDDFRGHGRATMGVKNMQV--ERDVVIHSRAVADTDEIFVMTASGVVIRTSVNSIRITGRGAKGVKIMRLDEKDKVIGVAIVTPEPGVEADPE............. 821
175 0.000e+00UniRef50_A0A2W5G7J4 DNA gyrase subunit A n=1 Tax=Pseudomonas fluorescens TaxID=294 RepID=A0A2W5G7J4_PSEFL  ali  42  3.......TTPPSSTVMQSNIQPITIEEEMRKSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAQSAMGNDYNRKHLKSARVVGDVMGKFHPHGDGAIYDAMARMAQDFSLRLPLEDGQGNFGSMDGDSPAAMRYTEIRLSKAGSAMLSDIDEDTVDFQPNYDGSEQEPRVLPTRIPNVLVNGGGGIAVGMATNIPPHNLGEIIDACLHLIDNPNADPLELNEIVKGPDFPTGGIIVGRSAILSGNASGRGSITVRAKVEIQDPDTKPVIIVNEVPYQVNKANLIIKIADLVKDKVIEDISDIRDESDRFGVRVVIELKRNTNAEVVLNQLYKHTDLQTSFSYNMVVLDGGLPKLLGITPMLRAFLNHRDEVVTRRTKFRLAKARDRAHILVGLGIAVGNIDEVIKIVRNAPDPSIAKEQLMERAWLSNLQAQAILDLRLHRLTGLERDKILAEAAEIAESIRYLLSILSDRGVLFQVIKDELIEVKANFATPRRTEIVD-GGADMAMEDLIPPEDVVVTISSDGYVKRVPLATFRAQRRGGKGKAAANLRENEEMSNLFVANTHDPLLFFTNKGNVFKLKVYELPQATATSRGKAFVNLLQLAKDEHVAASVPIPRWSSQFLVFATQNGMIRKTPLSAYANVRSTGIYGMGLGNGDKLLDVHEAPSAASILMSSANGSAVRFSADEIRPISRTSTGVRGMNLRPKDHVMAMYVLSQDEHILTVTENGYGKLTPASDYPEKGRGTMGVISIQTTNRNGNVVAALPVSLEDQIMIATNDGQLIRMNVADISIMGRNTQGVRLFSVT-DAQVRLVTRLNSKVLNAEGESNPEADVVPTEGVE 886
176 0.000e+00UniRef50_A0A1C6C8P4 DNA gyrase subunit A n=23 Tax=root TaxID=1 RepID=A0A1C6C8P4_9FIRM  ali  42  1.......MSDENFSLNNNRVVHRDIEKEMRESFLAYSMSVIVSRALPDVRDGLKPVHRRILYTMYENGLTPDKEYRKCADTVGTVLGRYHPHGDASVYDAMVRLAQDFSMRYPLVDGHGNFGSLDGDPPAAYRYTEARMDKMALDMLTDINKDTIDYMSNYDDRLKEPVVLPSRFPNLLVNGSVGIAVGMATNIPPHNLTETIDAVQTLIKNPDCTLDELMQHIKGPDFPTGGIIMGRAGIRAAYATGRGRITLRGRAKIEDIKNRTCIIIEEIPYMVNKKRLIENIADLAKDKRIDGIHTIRDESDKHDVRIVIELKKDAIAQVVLNHLYQYTQLQDTVGVIMLALVKGEPKILSLKQMLTEYIDFQVEVIRRRTKFDLDKAQARAHILEGMVIAAENIEEVIRICRTSENITEIKQRLMARFSLTEIQADAIAQMRMYQLSNMEXXXXXXXXXXXXXXXXXXXXXXXXXXXXLEIICNELEEIKRKYGDERRTSI-ENVSGEVDVEDLIPVEDCVVTLTNIGYIKRQPISEYKTQKRGGKGVSAIKQRDEDFIQEMFISSTHDDVLFITSKGIMYKLRCYEIAEGSKQSRGVNVINMLPLAEDEKIAAMIKTTDYEDKFLIMVTKNGKIKRTPLSAYKNVRKNGLRAVGLDDGDEIAGVRLTDGSAQVIVATRNGYAIRIDETQMRPMSRTAHGVKAIKLRDGDYVVSIARVREGASVLTVTDKGLGRRVKLDDYRIQNRGGYGMLNYKVSDDKGYVCGIKIVDEGDDIIMIATDGVIIRIRACDIRIMGRYATGVKLMRVSGEDRVVAFTRAEHDDSAETEKIEQ........... 822
177 0.000e+00UniRef50_A0A258FWW0 DNA topoisomerase (ATP-hydrolyzing) n=1 Tax=Candidatus Saccharibacteria bacterium 32-50-10 TaxID=1970480 RepID=A0A258FWW0_9BACT :  ali  45  2...PEEDNFDPTLPEPVDGLEHRTVEDVMEDSFLRYSMSVIIDRALPDVRDGLKPVHRRILHTMNRDGLRAGAKFRKSATVVGSVMGDFHPHGDSSIYDAMVRLAQPWALRYPMVEGQGNFGSMDGDPAAAYRYTEARLQKIADEMVADIDKDTVDFRDNYDGSKQEPVVLPAKVPNLLLNGQIGIAVGMATNIPPHNLGELVDASIELIDNEEATLDDLLKHVKGPDFPTGAIVYGGAPMKQAYLTGRGSVTVRAVADIETKKGRHQIVVTEVPYGVNKATLIEKIAELVKDKKLAGISDLRDESSRGSVKVVIELKKDAYPKKLLNQLFKMTALQTSFNYNMLALIDGQPRILGLEEMLKEFVKHRQKVVRRRTEFELKKAQDRAHVLEGLKIALDHIDEVIALIRASKTTEIAHAGLMKTFGLSDIQASAILAMQLRRLTGLEXXXXXXXXXXXXXXXXXXXXXLADEKEILKIIKTELLEMKEKYGDERRSKIINHELGKFSDEELIPEEDSIILLTTENYIKRTLVSEYRRQHRGGKGKRGMTTKDEDVIDQLIPASTHDYLLFKDSN--------------------------------------------DDGYLFMSTTKGTVKKTPLKDYANIRTNGLIAIKLDDGDELRWIKQTSGQDDVIISTSAGQAIRFGEADARPMGRSARGVRGVRLRPHDEVVGMDIVSSDDNLLVISQNGYGKITKAKNFPCHKRGGVGIKAAVVTAKTGPIVAVRALEDTDEILLISSKGQAIRVGLADIPTLGRTTQGVRIMRMSDGDKVTSFGFVPAKKDDDVEVEEAK.......... 787
178 0.000e+00UniRef50_UPI000C7CDB96 DNA gyrase subunit A n=2 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI000C7CDB96  ali  40  2.....TEQSTPGGGKNPPGIEPISIIEEMQRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYGMSELGIDWNKKYVKCARVTGDVMGKYHPHGNAAIYDALARMAQDWSLRLPLIDGQGNFGSVDGDPPAAERYTECRLQKAAHSLLDDLDKETVDFRDNYDGTLHEPVVVPAKFPNLLVNGAGGIAVGMATNIPPHNLGEVIDACIALIDNPAIELPELMQIIPGPDFPTGALILGRSGIRQAYETGRGSVIMRGRAHIEPMGDREQIIITEIPYQVNKSTMIEKMAELVRDKRIEGISDLRDESDRQGYRVVVELKRDANAEVILNQLYRYTPLQTSFGCNMVALNGGKPEQMTLLDMLRAFVSFREEVVSRRTKYLLRKARERAHVLVGLAIAVANIDEVIKLIRQAPDPQTAREQLMERRWLSEEQARAILELRLQRLTALGRDEIGDELNKIGDEIKDYLDILSSRLRIMQIVKDELTSVRDEFGTPRRTEIAE-GGPDMDDEDLIAQEDMVVTVSHLGYIKRVPLTTYRAQRRGGKGRSGMATRDEDFVTRLFVANTHTPVLFFSSRGIVYKEKVWRLPIGTPQSRGKALINMLPLEPGERITTIMPLPEWQNLDVMFSTTRGTVRRNKLSDFVQVNRNGKIAMKLEEGDEILSVDTCTEFDDVVLTTALGQCIRFPVADVRVAGRNSIGVRGISLGDGDRIISMAIVAHEQFILTVSKKGFGKRSSSYDFRTSGRGGKGIRATDTSKEIGELVAAFPIEHNDQIMLVSDGGQLIRVPVEGIRLASRATKGVTIFSTAKDEKVVSVERISEPDGDEEIEAVGAEGV....... 938
179 0.000e+00UniRef50_A0A2E0NF06 DNA gyrase subunit A n=5 Tax=Opitutae TaxID=414999 RepID=A0A2E0NF06_9BACT  ali  40  2..................RAEPTSITDIMQTAYIDYSMSVIVSRALPDARDGFKPVQRRILYAMLREGLLHNRPFDKCAGVVGEVLKNYHPHGDGSVYDTLVRLAQNWVMRYPLIVPQGNFGSIDGDSPAAYRYTECKLEQIAEDILKDIDEDTVDFVPNYKESTTEPSVLPAALPNLLMNGSTGIAVGMTTNIPPHNLIEIIDATTAIINDPKIDLDELIGIIPGPDFPGGGFIHGKSGIESYLKTGRGIVRTRGIAEVVEAKGKEEIIISAIPYNVNRASLVMRIAELIKDKAIDGISDLRDESTET-TRIVIELKRGAIPRVIINQLYKSTALESSFGVILLALDNRRPKQMNIKEMLTCYIDHRREVIYRRTAFRLRKAESRAHILEGYKLALDNLDDFVKIIRASSNREEAKQGLMVKYPLTEVQTNAILELRLYQLTGLERDKIEEEYAQLMALITELKDIXXXXXXXXXXXXXXXXXXXXXYGNSRRAQIIS-VDGDISMEDLIPNEGCMITVTHNGFIKRTSLDEYRSQKRGGKGVIGSGQYEDDFVEHLFTASTHDYIMCFMNTGRVYVEKVYHIPEGSRTAKGRAIANVLELQEGEKIAAMICVKDFDDQRIVLATNKGVTKKTLLSDFRNFRKGGIIGIKIDDGDALVGARLTTGDDDIILITSNAQSIRFSEKDLRDQGRATRGVRGIKKSQNDKVVSIEIVDPNAKLLIAGANGLGKRSSFDEYRRQSRGGSGIIAIKSKK----VSGALSVTDEDEIMMFTLKGQAVRSPIKDVSVVGRTTQGVKLVNLSDKDELIGISKVIASEEDEAGSNEEDNPEQVQEVVE 819
180 0.000e+00UniRef50_A0A2D6EJQ4 DNA gyrase subunit A n=3 Tax=Proteobacteria TaxID=1224 RepID=A0A2D6EJQ4_9PROT  ali  41  1..........MAEFIEEKGVERISIVDEMKASYMEYAMSVIVSRALPDVRDGLKPVHRRILYAQHELSNYWNRAYKKSARIVGDVMGKYHPHGDQAIYDTLVRLAQDFSMRLPLADGQGNFGSMDGDKAAAMRYTEVRMAKAAHAMLSDIEKDTVDFVPNYDGNDQEPTVLPTRFPNLLVNGTAGIAVGMATNIPPHNLCEVVDATVHLVDNPTASNETIGEYIQGPDFPTGGICLGLAGIKTAVADGRGSVVVRAKTHIEEKSGKQSIIVDEMPYQVNKANMIKRIAELVQEKLIEGISDLRDESDRDGVRVVVELRRDANAEVVLSQLLKHTSMQTSFGYNMLAIHNGRPKLMGMREVLNAFIAHREEVIRRRTRFDLNKARARAHILVGLATAVANIDEIIKIIRHAANPAEAKQQLMAQPWMSEIQAQAILDLRLHRLTGLERDKIQDEANEIAAIIRDLVEIXXXXXXXXXXXXXXXXXXXXXFGTPRRTEIME-GSAEVDMEDLIKPEEMVVTISSDGYVKRQPMDDYRAQRRGGKGRSAANMKEDEQIQDFFIANTHSPLLFFTTIGKVHKLKVYNLPVASSGARGKAFVNLLPLEKDEKVMRVVRIPDWEGKVLMFATEQGLIRKTPLTAFNNVHKNGIKGISLNEGDALINVALAEENSDIIMNSANGQAVRFANESLRSISRTAYGVKGMTLKDGDKIVSADVIHGEEYILTVTENGFGKRTPCDDFPTKSRGTMGVIAIKTSDRNGQVIASLPVSDGDHVMIATSDGQVIRMAVDDISVIGRNTQGVTLFKT-DGAKVFSVARIPADEDELEADVVVDEDGNPIEATQ 863
181 0.000e+00UniRef50_P48371 DNA gyrase subunit A n=724 Tax=cellular organisms TaxID=131567 RepID=GYRA_NEIGO  ali  42  15..................ETLPVSLEDEMRKSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMHELKNNWNAAYKKSARIVGDVIGKYHPHGDSAVYDTIVRMAQNFAMRYVLIDGQGNFGSVDGLAAAAMRYTEIRMAKISHEMLADIEEETVNFGPNYDGSEHEPLVLPTRFPTLLVNGSSGIAVGMATNIPPHNLTDTINACLRLLDEPKTEIDELIDIIQAPDFPTGATIYGLGGVREGYKTGRGRVVMRGKTHIEKNGERERIVIDEIPYQVNKAKLVEKIGDLVREKTLEGISELRDESDKSGMRVVIELKRNENAEVVLNQLYKLTPLQDSFGINMVVLVDGQPRLLNLKQILSEFLRHRREVVTRRTLFRLKKARHEGHIAERKAVALSNIDEIIKLIKESPNAAEAKEKLLARPWLSEIQADAILRMSLRNLTGLDQKEIIESYKNLMGKIIDFVDILSKPERITQIIRDELEEIKTNYGDERRSEINPF-GGDIADEDLIPQREMVVTLTHGGYIKTQPTTDYQAQRRGGRGKQAAATKDEDFIETLFVANTHDYLMCFTNLGKCHWIKVYKLPEGGRNSRGRPINNVIQLEEGEKVSAILAVREFPDQYVFFATAQGMVKKVQLSAFKNVRAQGIKAIALKEGDYLVGAAQTGGADDIMLFSNLGKAIRFNEYGVRPSGRGSGGLRGMRLPADGKIVSLITFAPETEVLTATANGYGKRTPIADYSRKNKGGQGSIAINTGERNGDLVAATLVGETDDLMLITSGGVLIRTKVEQIRETGRAAAGVKLINLDEGETLVSLERVAEDESELSGASVISNVTEPEAEN. 916
182 0.000e+00UniRef50_A0A1Z9LD51 DNA gyrase subunit A n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A1Z9LD51_9GAMM  ali  43  6.................KEIINVNIQDELKQSYLSYALSVIHGRALPDIRDGLKPVHRRILFAMHDLKNTYNKPYKKSARVVGDVIGKYHPHGDSAVYEAMVRMAQDFSMRYMVVEGQGNFGSIDGDRPAAMRYTEVRMAKITDQMLGDLEKDTVSFSPNYDGSEFIPDVLPTKIPNLLINGSSGIAVGMATNIPPHNLTEVINGCLRLLSNPKTSIDELIQDISGPDFPTGGTIDGKAGIYEAYKTGRGIIHIRSNTTIEEDKGKQSIVVNEIPYMVNKAKMLEKIAELVKEKKIEGITEIRDESDKDGLRVVIEVRKGDSVEVLENNLFSQTQLEQSFGINLTVLSEGQPKEVNLKEILEAFIGHRKDIITKRTIFDLKKAKERGHIVEGLMVAIANXDEVITIIKKSKDPKVAAAALVKKSWLSAEQAKAILELRLGRLTGLEQDNLNAEFNDIVTKILELQKILDDKSTLEALLVSELNEIKDNFGDERRTLINDTR-RGITNEDLIPEETRVLTISRSGYAKTQPLDEYREQKRGGQGKAAASVKEEDLIQNLYVLSSHTQILCFTTKGKVFWLKVYEIPVASRTSKGRPXVNMLXLDDDESVSEILPVEFSDDKFIFMATKNGTTKKTNLSLFSKKYKSGIKAINLDDDDRLIGTAITDGNQQILLASSAGKLIRFNEEHVRHMGRTARGVRGMKLKKGEKIISLMIADNTKTVLCVSENGYGKKTNLDDFPSHNRGGQGVISMKTSERNGAMVSSALVNDDAGIMLISDKGTMIRTSVSQIPTLSXNTQGVKVITPKEGEKLIECVTIP....................... 839
183 0.000e+00UniRef50_A0A1C7HIP7 DNA gyrase subunit A n=32 Tax=Bacteria TaxID=2 RepID=A0A1C7HIP7_9BURK  ali  41  1MAKSPKDKDDIRDILETH-YEKVNLTDEMQTSYLDYAMSVIMGRALPDVRDGLKPVHRRVLYAMSELGNTYRSPYKKSARVVGDVIGKYHPHGDAAAYETIVRMAQDFSMRYCTVDGQGNFGSVDGDSPAAQRYTEVRMTRIASDMLAGIDQETVDFVPNYDASEVEPTVLPTRVPTLLINGSAGIAVGMATNVPPHNIVEAINACLLVLDRPDCTIDEIMELLPAPDFPTGGIIYGLGGIREAYRTGRGKAIIRAKTEIEEIEDREAIIVKEIPYQVNKSQMLEKIAQLGSEKKIEGISFVRDESDKDGIRGVIELKRGANTEVVLNNLYKITELESSFGINLVALVDGQPKLLNIKEIIEAFINHRWEVTTRAALFQLKTARSKIYLLEGQAVALANIDEFIEVIKTSANGAEAEERLLSRSWPSAAQAKNILQLRLQTLTGLEHERIEKDYAELAEEIHQLVTLLNNRDLMQQKIAADLREVQESYGDARRSEIVA-DAKDFKTKDLIPLREMVVTMTDTGYIKSQASAEYRAQKRGGQGRKATEVKEGDIISKLFVATTHDVLLCFTDKGRMFWLNVWDLPEGSSNSKGRPIVNLLEL-NDEKVSVVLPIDFQKDLYVFMATANGTVKKTPISDFKNQRKAGIIAVNLVEGDYLIGAAITDGVHDVMLFNDEGKAVRFAEEDVRSMGRTATGVRGMRLEGDSKVIAMLVAQEDDTVLTVTENGYGKRTPINDYTRHGRGTKGMISIQTSERNGKVVSALLVNDNDEIILLNSAGKLVRTRVNEIRVMGRNTQGVRLISMDQGVTVIGVERVTENDDGAAEDETK........... 868
184 0.000e+00UniRef50_UPI0009EDBE8B DNA gyrase subunit A n=2 Tax=Opitutaceae TaxID=134623 RepID=UPI0009EDBE8B  ali  39  4...............SNEKLSSANITDIMQTAYIDYSMSVIVARALPDARDGLKPVQRRILYAMMREGLLHNRPFDKCAGVVGEVLKNYHPHGDSSVYDTLVRLAQTWVMRYPLIDPQGNFGSVDGDPPAAYRYTESRLNEIAEDLIRNIDEDTVDFVPNYKESTTEPTVLPSALPNLLMNGSTGIAVGMATNIPPHNLGEIIDATCAIIDNPAISVDALCSIVQGPDFPTGGTIAGRAGILSYLTTGRGIVRIRGRAHTEETKGGEVIIITEIPYNVNRANLVSKIAELISDKAIDGIRDLRDESDEN-TRIVLELKRGEQARPILNQLYQKTALEASFGVTLLALDQKRPKQMNIKELIECYIEHRREVITRRTQFRLRQAEDRAHILEGYLIALDNLDDFVKIIRSSANRLEARERLMEKYPLSQRQTDAILELRLYQLTGLERDKIEAEYRDLMGLIEELRAILASEEKLFALIKKELLEMRAKYATARRTEITA-AAGEFRMEDFIPNEGCVITVSHLGFIKRTPVAEYRSQKRGGKGIIGADTYEEDFVEHLFTAETHDYILFLTTKGQCLAKKVYDVPEGTRASKGKSVKSFLSLSEGERIAAMICVKDFDPGHLVMATKSGITKKTSLADYANTREGGLRGIKLLDDDSLVGCVLTNGENEIMLVSHRGQAVRFKESDLRDQGRGTQGVTGMRFKEGDYVQAIEVCDHDARLLVAREDGVGKRTPFADYRLISRGGTGVIAIDLPDDGSAVAGALSVHESDEVMLLTTKGQSIRTRVREIRETGRGAKGVKLLTLAPGDSILSIARIVETD.................... 810
185 0.000e+00UniRef50_A0A2E7PEX8 DNA gyrase subunit A n=15 Tax=Chloroflexi TaxID=200795 RepID=A0A2E7PEX8_9CHLR  ali  42  1.......MVTTTPQEPDSGERPIRIEEEMRTSYLTYAMSVIVSRALPDVRDGLKPVQRRIMYAMHDMGIRPNSAYRKSARIAGEVLGKFHPHGEGSVYDALVRMAQDFSMRYPLITGQGNFGSIDGDPPAAMRYTEARLAPISDELLADIDQNTVDFSPNFDDSLGEPSVLPSRLPNMLINGASGIAVGMATNIPPHNLGEICDAINLLVDDPDVTVERLMRVVKGPDFPTGANIHGRQGIYDTMTTGRGRIMMEATTEIEEVGGREQIIVTELPYQVNKANLVEKIATLTREKKLEGISDIRDESDRHGMRIVIELRRDAQTYVVMNNLMRHTALRQSFNTIMLALVDGQPQVLPLKRCLALFIAHRQEVIRRRSEFQLEKARDRDHIVQGLLLALERMDEVIEIIRASADVETARTNLMSSLDLSEAQAQAILDMQLRRLAALEXXXXXXXXXXXXXXXXXXXXXLADPALVLAEIKSETSALKKSFGNPRRTVIHDAEIADQSDESFIPKEDVIITLSQKGYVKRVPSDTFRTQHRGGKGVVGMRTREDDAVMDLVVVDTHDTLFFFTNRGRVYPLKAYQIHDSSRTSRGVLLANLLPLDRGEMVQAMLLIENPRDEYLLIATKMGEIKALKTGELTRIRPSGLIVMDLEQGDELISVAQVGDAKDVVMVTENGQAIKFPISGLTPRSRTAGGVRGIRLLNKDKVVAMSAVTPNSHLLIVSQRGYGKSTPLASYPRHSRGGQGVRTFRTSDKAGNVAAARVVSEGQLILIISEKAQVVRITLEDVRVTGRNTQGVIVWRDREDDQVASIACFQESE.................... 818
186 0.000e+00UniRef50_D5EPI4 DNA gyrase subunit A n=35 Tax=root TaxID=1 RepID=D5EPI4_CORAD  ali  39  2.....SDNPSDSNTPSHMRAQATSITDIMQTAYIDYSMSVIVSRALPDARDGFKPVQRRILYAMLREGLLHNRPFDKCAGVVGEVLKNYHPHGDSSVYDTLVRLAQDWVMRYPLIVPQGNFGSIDGDSPAAYRYTECKLQAIAEDCLKDIDEDTVDFVPNYKESTTEPSVLPAALPNLLMNGSTGIAVGMTTNIPPHNLNEIIDAACAIIDNPKIELDELIQFIPGPDFPGGGFIHGKSGIESYLKTGRGIVRTRGVAEVVENKGKEEIIISAIPYNVNRASLVMRIAELIKEKAIEGISDLRDESTEE-TRIVIELKRGAIPRVIINQLYKSTALESSFGVILLALDNRRPKQMNIKEMLTCYIDHRREVIYRRTAFRLRKAEARAHILEGYKIALDNMDDFVKIIRASKNREEAKVSLMAKYPLTEIQTNAILELRLYQLTGLERDKIEEEYRKLMELIGELKDIXXXXXXXXXXXXXXXXXXXXXYGNPRRSQVIA-VDGDISMEDLVPNEGCMITVTHKGFIKRTSLDEYRSQKRGGKGVIGSGQYEDDFVEHLFTASTHDYVMCFMNSGRVYVEKVYHIPEGSRTAKGRAMANVFELQEGEKIAAMICVKDFDEQSIVLATENGVTKKTKLSDFRNHRKGGIIGINIDEGDNLVGARLTSGEDDIILVTSNAQSIRFPETDLRDQGRNTRGVRGIKKSENDKVVAIEIVDDEAKLLIAGANGLGKRTEFSEYRQQSRGGSGIIAI----KSDKVAGALSVTDADEIMMFTLKGQAVRSPIDTVRVTGRAASGVKLVNLGNKDELIGISKVIASGEGEDAVEGEAPDEVATEAPE 837
187 0.000e+00UniRef50_A0A1G2CH36 DNA gyrase subunit A n=3 Tax=Parcubacteria group TaxID=1794811 RepID=A0A1G2CH36_9BACT  ali  43  2.................SNIEKREITTELQESYLNYAMSVIVSRALPDVRDGLKPVQRRILWDMWDSGLIYATKTRKCATVVGQVLGRYHPHGDVAVYDTLVRMAQDFSLRYPLIQGQGNFGSVDGDGAAHYRYTEAKLAKIAEEVLLDVEKETVDWQSNYDDTRQEPKVLPAKLPNLLLNGTVGIAVGMATNIPPHNLSEVADAVLYFADNQNADTDDLLKFVKGPDFPTGGIIFDQKGIREVYASGRGPILTRAKTDIQERKGKWDIVITEIPYQVNKSELIKHIAELVTNKRIEGIRDIRDESDREGMRVVIELKTDANPQKILNQLYQYTDLQKHFHMNMIALADGQPQLMTLKDVISAYFEHRKKIVRRRTEFDLKKAKERAHILEGLYKALGMIDKIIAVIKKSKDKNDAHQNLVKQFKLSDIQANAILEMRLQTLAALERKKIEDELKEKMALIKDLEIILKSPAKIVNIIKGEVKELKEKYGGERKTAVVVGGVKTFSDEDLVPEEEAVITLSAGGYIKRLPPDAFKAQKRGGKGLIGSDVSEEDLITQFFGARTHDNVLFFTDRGRVFQTKVHEIPAASRTSKGRAIHNFLELPSDENVSAVVNYADRESAYLIMVTKNGVVKKTSLEDFKNIRRNGIIAISLKKGDALNWVRLSSGGDQVFLGTKNGQAIRFKESQVRPMSRTAGGIRAIRLKKGDVVAGFDIIKQNTDVLVVMANGFGKQTPLKEYKLQNRGGSGIKTANITAK<