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Query: gi|15607161|ref|NP_214533.1| hypothetical protein (Rv0019c) [Mycobacterium tuberculosis H37Rv], from M.tuberculosis

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MQGLVLQLTRAGFLMLLWVFIWSVLRILKTDIYAPTGAVMMRRGLALRGTLLGARQRRHAARYLVVTEGALTGARITLSEQPVLIGRADDSTLVLTDDYASTRHARLSMRGSEWYVEDLGSTNGTYLDRAKVTTAVRVPIGTPVRIGKTAIELRPLast
1 -50.6001r21_A mol:protein length:128 Antigen Ki-67  ali model follow..  17  1................................................GSPEFPGGMWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRGIECDIRIQLPVVSKQHCKIEIHEQEAILHNFSSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYE. 106
2 -50.0002kkl_A mol:protein length:140 Uncharacterized protein Mb1858  ali model follow..  30  4................................ADFLSELDAPAQAGTESAVSGVEGLPPGLALLVVKRGPNAGSRFLLDQAITSAGRHPDSDIFLDDVTVSRRHAEFRLENNEFNVVDVGSLNGTYVNREPVDSAV-LANGDEVQIGKFRLVF.. 123
3 -49.7002kb3_A mol:protein length:143 Oxoglutarate dehydrogenase inhibitor  ali model follow..  29  19.................................RADLLKEMESSTGTAPASTGAENLPAGSALLVVKRGPNAGARFLLDQPTTTAGRHPESDIFLDDVTVSRRHAEFRINEGEFEVVDVGSLNGTYVNREPRNAQV-MQTGDEIQIGKFRLVFL. 138
4 -48.5002xt9_B mol:protein length:115 PUTATIVE SIGNAL TRANSDUCTION PROTEIN GARA  ali model follow..  35  1..................................................GSGVEGLPSGSALLVVKRGPNAGSRFLLDQPTTSAGRHPDSDIFLDDVTVSRRHAEFRLEGGEFQVVDVGSLNGTYVNREPVDSAV-LANGDEVQIGKFRLVFL. 103
5 -47.1002kfu_A mol:protein length:162 Rv1827 pThr 22  ali model follow..  30  28.................................DFLSELDAPAQAGTESAVSGVEGLPPGSALLVVKRGPNAGSRFLLDQAITSAGRHPDSDIFLDDVTVSRRHAEFRLENNEFNVVDVGSLNGTYVNREPVDSAV-LANGDEVQIGKFRLVFL. 147
6 -46.8003oun_A mol:protein length:157 Putative uncharacterized protein TB39.8  ali model follow..  26  34..................................QSGAPDYGQPAPGGYSGYGQGGYGSAGTSVTLQLDDGSGRTYQLREGSNIIGRGQDAQFRLPDTGVSRRHLEIRWDGQVALLADLNSTNGTTVNNAPVQE-WQLADGDVIRLGHSEIIVR. 152
7 -46.1002lc1_A mol:protein length:100 Putative uncharacterized protein TB39.8  ali model follow..  28  1.......................................................GHGSAGTSVTLQLDDGSGRTYQLREGSNIIGRGQDAQFRLPDTGVSRRHLEIRWDGQVALLADLNSTNGTTVNNAPVQE-WQLADGDVIRLGHSEIIVR. 98
8 -45.5003po8_A mol:protein length:100 Putative uncharacterized protein TB39.8  ali model follow..  29  1..........................................................SAGTSVTLQLDDGSGRTYQLREGSNIIGRGQDAQFRLPDTGVSRRHLEIRWDGQVALLADLNSTNGTTVNNAPVQE-WQLADGDVIRLGHSEIIVR. 95
9 -45.3001mzk_A mol:protein length:139 KINASE ASSOCIATED PROTEIN PHOSPHATASE  ali model follow..  25  2.......................................................PLGSSWLFLEVIAGPAIGLQHAVNSTPVKLGRVSPSDLALKDSEVSGKHAQITWNSTKWELVDMGSLNGTLVNSHSISHPVELASDDIITLGTTTKVY.. 116
10 -45.3002jqj_A mol:protein length:151 DNA damage response protein kinase DUN1  ali model follow..  16  2............................................AKRQQRSNKPSSEYTCLGHLVNLIPGKEQKVEITNRNVTTIGRSRSCDVILSEPDISTFHAEFHLFQRNLINVIDKSRNGTFINGNRLKKDYILKNGDRIVFGKSCSFL.. 118
11 -44.8001uht_A mol:protein length:118 expressed protein  ali model follow..  25  1.................................................GSSGSSGMVTPSLRLVFVKGPREGDALDYKGSTIRVGRIVRNEIAIKDAGISTKHLRIESDSGNWVIQDLGSSNGTLLNSNALDTSVNLGDGDVIKLGEYTSIL.. 108
12 -43.8003uot_A mol:protein length:122 Mediator of DNA damage checkpoint protein 1  ali model follow..  18  2...............................................SQSSESLRCNVEPVGRLHIFSGAHPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEIWDKAPILRDCGSLNGTQILRPPKVVSHRLRDQELILFADLLCQYH. 115
13 -43.1006cah_A mol:protein length:108 ABC transporter ATP-binding/permease protein Rv1747  ali model follow..  26  1.....................................................GHMWNLATSMMKILRPG--RLTGELPPGAVRIGRANDNDIVIPEVLASRHHATLVPTPGGTEIRDNRSINGTFVNGARVDAAL-LHDGDVVTIGNIDLVFA. 98
14 -42.8003va1_A mol:protein length:132 Mediator of DNA damage checkpoint protein 1  ali model follow..  16  3.............................................SSSSGLVPRGSHMEPIGQLRLFSGTHPERDFPLYLGKNVVGRSPDCSVALPFPSISKQHAVIEIWNKAPILQDCGSLNGTQIVKPPRVVSHRLRDQELILFADFPCQYH. 118
15 -42.6006c4u_B mol:protein length:134 Forkhead-associated 1  ali model follow..  12  1.............................................GENIVFRVISTTGQIPIRDFSADISQVLKEKRSIKKVWTFGRNPACDYHLGNIPVSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVESYQLLSQGDEITVRTDPTGTI. 112
16 -42.5003gqs_A mol:protein length:106 Adenylate cyclase-like protein  ali model follow..  26  1.........................................................QPSRFLLKVLAGANIGAEFHLDSGKYIVGSDPQADIVLSDMSISRQHAKIIIGDNSVLIEDLGSKNGVIVEGRKIEHQSTLSANQVVALGTTLFLLVD 101
17 -41.6006ccd_A mol:protein length:111 ABC transporter ATP-binding/permease protein Rv1747  ali model follow..  25  2.......................................................SQPAAPPVLTVRYEG--SERTFAAGHDVVVGRDLRADVRVAHPLISRAHLLLRFDQGRWVAIDNGSLNGLYLNNRRVPV-VDIYDAQRVHIGNPD..... 93
18 -41.6003un0_B mol:protein length:115 Mediator of DNA damage checkpoint protein 1  ali model follow..  19  2......................................................SCNVEPVGRLHIFSGAHPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEIWDKAPILRDCGSLNGTQILRPPKVVSHRLRDQELILFADLLCQYH. 108
19 -40.7002csw_A mol:protein length:145 Ubiquitin ligase protein RNF8  ali model follow..  20  1.............................................GSSGSSGVTGDRAGGRSWCLRRVGMSAGWLLLEDGCEVTVGRGFGVTYQLVPLMISRNHCVLKQNEGQWTIMDNKSLNGVWLNRARLERVYSIHQGDYIQLGVPLENKE. 116
20 -40.1003hx1_A mol:protein length:131 Slr1951 protein  ali model follow..  17  2....................................................SDPSAKPLQEHILIILDDAGRREVLLTETFYTIGRSPRADIRIKSQFVSRIHAVLVRKSSDGDEDGQSSVNGLMINGKKVQEHI-IQTGDEIVMGPQV..... 108
21 -39.5002pie_A mol:protein length:138 E3 ubiquitin-protein ligase RNF8  ali model follow..  19  1.....................................................GAHMAGGRSWCLRRVGMSAGWLLLEDGCEVTVGRGFGVTYQLVPLMISRNHCVLKQNEGQWTIMDNKSLNGVWLNRARLERVYSIHQGDYIQLGVPLENKE. 108
22 -39.2005t2s_A mol:protein length:264 DDK kinase regulatory subunit DBF4,Serine/threonine-protein kinase RAD53  ali model follow..  14  108......................RFLKNLDVDLDHVDGSKFSQEQIGENIVCRVICTTGQIPIRDLSADISQVLKEKRSIKKVWTFGRNPACDYHLGNISLSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVNSNQLLSQGDEITVGVGVESDI. 242
23 -38.6005t2f_A mol:protein length:269 DDK kinase regulatory subunit DBF4,Serine/threonine-protein kinase RAD53 chimeric protein  ali model follow..  13  123................................GASGGSKFSQEQIGENIVCRVICTTGQIPIRDLSADISQVLKEKRSIKKVWTFGRNPACDYHLGNISLSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVNSNQLLSQGDEITVGVGVESDI. 247
24 -37.5004a0e_A mol:protein length:123 TYPE III SECRETION PROTEIN  ali model follow..  14  1.........................................................GGGSWVCRFYQGKHRGVEVELPHGRCVFGSDPQSDIVLSDSEIAPVHLVLMVDEEGIRLTDSA--EPLLQEGLPVPLGTLLRAGSCLEVGFLLWTFVA 97
25 -37.3004d9v_A mol:protein length:123 YscD; putative type III secretion protein  ali model follow..  14  1.........................................................GPVSWVCRFYQGKHRGVEVELPHGRCVFGSDPQSDIVLSDSEIAPVHLVLMVDEEGIRLTDSA--EPLLQEGLPVPLGTLLRAGSCLEVGFLLWTFVA 97
26 -37.2004ym4_A mol:protein length:141 TRAF-interacting protein with FHA domain-containing protein A  ali model follow..  12  14..........................................................PGQLQCGIFQSISFNREKLPSSEVVKFGRNSNCHYTFQDKQVSRVQFSLQLFKKSFEIKNMSKKTNLIVDSRELGNKMDLPYRCMVRFGEYQFLME. 118
27 -37.0001qu5_A mol:protein length:182 PROTEIN KINASE SPK1  ali model follow..  15  1................................EAETREQKLLHSNNTENVKSSKKKGNGRFLTLKPLPDSIIQESLEIGVNPFFIGRSEDCNCKIEDNRLSRVHCFIFKKRHAIWYCHT-GTNVSYLNNNRMGTKFLLQDGDEIKIIWDK..... 136
28 -36.8005a8i_A mol:protein length:214 ARNA  ali model follow..  22  76.................................QPEPAQPQPVSSTPAPQQASQPTNRYYIYFIQTPNENLVNKKVLLNFPSVSMGRSPENIVIVPDSEVSRKHAVIYLDNSELYIEDLNSTNGTYVYDGKQKGKQKIEPNSIIKLGNQTIVR.. 202
29 -35.6001lgp_A mol:protein length:116 cell cycle checkpoint protein CHFR  ali model follow..  20  5.............................................................GRLLRLGAEEGEPHVLLRKREWTIGRRRGCDLSFSNKLVSGDHCRIVVDSGQVTLEDT-STSGTVINKLKVVQTCPLQTGDVIYLVYRKNEPE. 101
30 -34.1001gxc_A mol:protein length:149 SERINE/THREONINE-PROTEIN KINASE CHK2  ali model follow..  11  3.................................VSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQD--GFANLECVNDNYWFGRDKSCEYCFDEPTYSKKHFRIFRENSYIAYIEDHSGNGTFVNTELVGKRRPLNNNSEIALSLSRNKV.. 135
31 -33.6004jon_A mol:protein length:127 Centrosomal protein of 170 kDa  ali model follow..  26  13.......................................................................GGTRHRLPREMIFVGR-DDCELMLQSRSVDKQHAVINYDTDEHLVKDLGSLNGTFVNDVRIPEQITLKLEDKLRFGYDTNLF.. 97
32 -33.0002n84_A mol:protein length:179 Uncharacterized protein  ali model follow..  22  47...................................VTDPTKLNAQVSYFQCPPWAALPSVACHLQCTRDGLPLPALGLHRFPYLFGRSKVCDYVLEHPSISSVHAVLVFHGGQFVLMDLGSTNGVKLNGNRIEKRLPAPVGSSIQFGFSSRVY.. 169
33 -32.2005yyx_A mol:protein length:141 Meiosis-specific serine/threonine-protein kinase MEK1  ali model follow..  24  2..........................................GSSSSGENLYFQHMGVAPAHLEVNVGGYNTEQTIPIKHQLVKVGRNDKCQLVLTNPSISSVHCVFWCSIPMFYVKDC-SLNGTYLNGLLLDKTYLLKHCDVIELSQGS..... 118
34 -31.9002w3o_A mol:protein length:113 BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE  ali model follow..  11  1.................................................GPHMGEVEAPGRLWLESPPGEAPPIFLPSDGQALVLGRGPLTQV--TDRKCSRTQVELVADETRTVAVKQLGVNPSTTGTQELKLEGSLGVGDTLYLVNGEHPLT. 106
35 -31.7001ujx_A mol:protein length:119 polynucleotide kinase 3`-phosphatase  ali model follow..  12  1.............................................GSSGSSGMSQLGSRGRLWLQSPTGGPPPIFLPSDGQALVLGRGPLTQV--TDRKCSRNQVELIADESRTVAVKQLGVNPSTVGVQELKLSGSLSLGDVLYLVNGLYPLT. 110
36 -31.1001yj5_C mol:protein length:143 5` polynucleotide kinase-3` phosphatase FHA domain  ali model follow..  12  2.....................................................SQLGSRGRLWLQSPTGGPPPIFLPSDGQALVLGRGPLTQV--TDRKCSRNQVELIADESRTVAVKQLGVNPSTVGVHELKLSGSLSLGDVLYLVNGLYPLT. 103
37 -30.0005e50_A mol:protein length:111 Aprataxin and PNK-like factor  ali model follow..  17  1.......................................................GPLGSMSGGFELQPRDGGPRVALAPGETVIGRGPLLGI--TDKRVSRRHAILEVAGGQLRIKPIHT-NPCFYQSSEKSLWCYLNPGDSFSMLVDKYIFR. 104
38 -29.6003uv0_A mol:protein length:102 Mutator 2, isoform B  ali model follow..  18  5................................................................VSLFFGGLPAILLKADTIYRIGRQKGLEISIADESMELAHATACILRRG--VVRLAALVGKFVNDQEETV-VDIGMENAVA-GKVKLRF.. 90
39 -29.2004h87_A mol:protein length:130 Kanadaptin  ali model follow..  26  1.........................................SMARAPPYQEPPWGGPATAPYSLETLKGGTILGTRSLKGTSCLFGRLSGCDVCLEHPSVSRYHAVLQHRGPGFYLYDLGSTHGTFLNKTRIPPRCRVHVGHVVRFGGSTRLF.. 126
40 -29.1005gm6_U mol:protein length:207 Pre-mRNA leakage protein 1  ali model follow..  18  115..............................................................................DTDLDDRTEIVVADIGIPEETSSKQHCVIQFRILKCYVMDLDSSNGTCLNNVVIPGAIELRSGDVLTLSEFEEDN.. 195
41 -28.3002jpe_A mol:protein length:140 Nuclear inhibitor of protein phosphatase 1  ali model follow..  19  4..............................GSPNSMAAAVNSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYLFGRNPDCDFTIDHQSCSRVHAALVYHKKRVFLIDLNSTHGTFLGHIRLEPHQQIPIDSTVSFGASTRAY.. 132
42 -28.3005w7w_T mol:protein length:108 Aprataxin and PNK-like factor  ali model follow..  19  1.........................................................SFTMSGGFELQPRDGGPRVALAPGETVIGRGP--LLGITDKRVSRRHAILEVAGGQLRIKPIHT-NPCFYQSSKPNLWCYLNPGDSFSLLVDKYIFR. 102
43 -28.2003els_A mol:protein length:158 Pre-mRNA leakage protein 1  ali model follow..  18  62.......................................................................RELGHSLDTDLDDRTEIVVADIGIPEETSSKQHCVIQFRILKCYVMDLDSSNGTCLNNVVIPGAIELRSGDVLTLSEFEEDN.. 149
44 -27.6002jkd_A mol:protein length:187 PRE-MRNA LEAKAGE PROTEIN 1  ali model follow..  18  20......................NNKEGIALKHVEPQDAISPDNYMDMLGLEARDRTMYELVIYRKNDKDKGPWKRYDLNGRSCLVGRELGADIGIPEETSSKQHCVIQFRILKCYVMDLDSSNGTCLNNVVIPGAIELRSGDVLTLSEFEEDN.. 172
45 -27.2003hue_A mol:protein length:341 DNA repair and telomere maintenance protein nbs1  ali model follow..  21  4...............................................................IEAEGDILKGKSRILFPGTYIVGRNVSSHIQVISKSISKRHARFTILTCEFEVKDLDTKFGTKVNEKVVNGDSYKEKDLKIQLGKCPFTIN. 110
46 -26.5003kt9_A mol:protein length:102 Aprataxin  ali model follow..  18  2............................................................MRVCWLVRQDSRHQRIRLHLEAVVIGRGPETKI--TDKKCSRQQVQLKAENKGYVKVKQVGVNPTSIDSVVIGQEVKLQPGQVLHMVNELYPYI. 97
47 -26.3006ar0_A mol:protein length:140 Sarcolemmal membrane-associated protein  ali model follow..  22  25...............................................................................DEPIKIGRSVANNATFDCKVLSRNHALVDHKTGKFYLQDTKSSNGTFINSQRLSPPCEILSGDIIQFG........ 106
48 -26.2003vpy_A mol:protein length:145 FHA domain-containing protein DDL  ali model follow..  24  21................................................................VFKDGEPLNEPLCLHRQSYLFGRERRADIPTDHPSCSKQHAVIQYRQVKPYIMDLGSTNKTYINESPIEPQYELFEKDTIKFGNSSREY.. 126
49 -26.1005z56_X mol:protein length:396 Smad nuclear-interacting protein 1  ali model follow..  19  230................................GALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSALLGRHRRADIPIDHPSCSKQHAVFQYRRVKPYIIDLGSGNGTFLNNKRIEPQYELKEKDVLKFGFSSREY.. 367
50 -25.3001wv3_A mol:protein length:238 similar to DNA segregation ATPase and related proteins  ali model follow..  10  70..........................................................DDITLQLYTEADYASFAYPSIQDTMTIGPNAYDDMVIQSLMNAIIIKDFQSQESQYVRIVHDKNTDVYINYELQEQTNKAYIGDHIYVEGIWLEVQA 168
51 -20.8001wln_A mol:protein length:120 Afadin  ali model follow..  17  31...........................................................................YRLQLSVTEVGTFDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVDGQRISETTMLQSGMRLQFGTSHV.... 108
52 -18.6005fwh_A mol:protein length:196 ESSC  ali model follow..  12  81.........................................................GQQMTIAWSGEEQRKYVYYVGQQSEVLVSNDPQADIETTNA-----RFSLRKHRGQWVVIPDDDAP-LFLNGVQLSDAVSLRNGDVLLCPYMQFVF.. 170
53 -18.1003j6d_A mol:protein length:392 Protein PrgH  ali model follow..  14  3.................................................TSKEKTITSPGPYIVRLLNSSLNGCEFPLLTGRFVVGQSDALTASGQLPDIPADSFFIPLDHGGVNFETDATEIILHELKEGNSESRSVQLNTPIQVGELLILIRP 114
54 -17.7003fm8_A mol:protein length:124 Kinesin-like protein KIF13B  ali model follow..  12  17.........................................................GDDKCFLVNLNADPALNELLV-KEHTLIGSANSQDIQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHF.... 112
55 -16.8004g2s_A mol:protein length:111 Protein prgH  ali model follow..  15  1.......................................................GSSPGPYIVRLLNSSLNGCEFPLLTGRFVVGQSDALTASGQLPDIPADSFFIPLDHGEIQVDTDATEIILHELKEGNSESRSVQLNTPIQVGELLILIRP 106
56 -16.6002eh0_A mol:protein length:130 Kinesin-like protein KIF1B  ali model follow..  17  26...........................................................................YYIKDGITRVGQERRQDIVLSGAHIKEEHCIFRSERSNVTLEPCERSE-TYVNGKRVSQPVQLRSGNRIIMGKNHV.... 108
57 -16.1002g1l_A mol:protein length:104 Kinesin-like protein KIF1C  ali model follow..  17  21...........................................................................YHIKDGVTRVGQV-DMDIKLTGQFIREQHCLFRSGEVVVTLEPCEGAE-TYVNGKLVTEPLVLKSGNRIVMGKNHV.... 99
58 -16.0005djo_A mol:protein length:174 Kinesin-like protein  ali model follow..  83...........................................................................YYLKDHTRVGAD-TSQDIQLFGIGIQPEHCEIDIAADGDITLTPKENARSCVNGTLVCSTTQLWHGDRILWGNNHF.... 157
59 -15.9004ejq_A mol:protein length:154 Kinesin-like protein KIF1A  ali model follow..  18  56...........................................................................YYIKDGITRVGRERRQDIVLSGHFIKEEHCVFRSDSRGVTLEPCEGAD-TYVNGKKVTEPSILRSGNRIIMGKSHV.... 138
60 -15.6003i6w_A mol:protein length:443 Serine/threonine-protein kinase Chk2  ali model follow..  18  35.........................................................................ANLECVNDNYWFGRDKSCEYCFDEPTYSKKHFRIFREVGPAYIEDH-SGNGTFVNTELVGKRRPLNNNSEIALSL....... 124
61 -15.4004egx_A mol:protein length:184 Kinesin-like protein KIF1A  ali model follow..  18  86...........................................................................YYIKDGITRVGRERRQDIVLSGHFIKEEHCVFRSDSRGVTLEPCEGAD-TYVNGKKVTEPSILRSGNRIIMGKSHV.... 168
62 -15.1005xzv_A mol:protein length:471 Serine/threonine-protein kinase RAD53  ali model follow..  23  63...............................................................................KKVWTFGRNPACDYHLNISRLSNKHFQILLGEDGLLLNDI-STNGTWLNGQKVNSNQLLSQGDEITVGV....... 134

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Doctor KS, Reed JC, Godzik A., Bourne PE. The apoptosis database. Cell Death Differ. 2003 Jun;10(6):621-33. Review.