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Query: gi|57116683|ref|YP_177686.1| fatty-acid-CoA ligase (Rv0035) [Mycobacterium tuberculosis H37Rv], from M.tuberculosis

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTAALLSPAIAWQQISACTDRTLTITCEDSEVISYQDLIARAAACIPPLRRLDLKRGEPVLITAHTNLEFLSCFLGLMLHGAVPVPIPPREALKTTERFMTRLGPLLRHHRVLICTPAEHDEIRAAASTDCQISRFTALAEAGDEQFGRATAQQLADTATADWPLCTLDDDAYVQYTSGSTAAPRGVVITYRNLLSNMRAMAVGSQFQHGDVMGSWLPLHHDMGLVGSLFAALFNSVSAVFTTPHRFLYDPLGFLRLLTSSGATHTFMPNFALEWLINAYHRRGADIEGIDLHKMRRLIIASEPVHAEGMRRFAATFAGVGLAPTALGSGYGLAEATVAVSMSAPNTGFRTETHAAAEVVTGGRVLPGYEVRIDAAPGARAGTIKLRGDSVAAKAYVGGKKLDALDEEGFCDTHDLGFLVDDEIVILGRQDEVFIVHGENRFPYDIEFIIRGESEQHRTKVACFGVNERVVVVLESPLDSIIDKAEADRLRCQVVAATGLQLDELITVRRGAIPTTTSGKLKRRAVAQAYRDGTLPRLATHAWTADPDSAPKTTRSSLEGAHLast
1 -124.0003pbk_A mol:protein length:583 Fatty Acyl-Adenylate Ligase  ali model follow..  26  18.DFPTLVDALDYAALSSAGMNFYDRRCQLEDQLEYQTLKARAEAGAKRLLSLNLKKGDRVALIAETSSEFVEAFFACQYAGLVAVPLAIPMGVGQRDSWSAKLQGLLASCQPAAIITGDEWLPLVNAA----------THDNPELHVLSHAWFKALPEADVALQRPVPNDIAYLQYTSGSTRFPRGVIITHREVMANLRAIHDGIKLRPGDRCVSWLPFYHDMGLVGFLLTPVATQLSVDYLRTQDFAMRPLQWLKLISKNRGTVSVAPPFGYELCQRRV--NEKDLAELDLSCWRVAGIGAEPISAEQLHQFAECFRQVNFDNKTFMPCYGLAENALAVSFSDEASGVVVNEVDVSTFVNCGKALPEHGIEIRNVAERVVGHICISGPSLMSGYFGDQVSQDEIAATGWLDTGDLGYLLDGYLYVTGRIKDLIIIRGRNIWPQDIEYIAEQEPEIHSGDAIAFVTQEKIILQIQCRIDEERRGQLIHALAARIQSEFGVTA-AIDLLPPHSIPRTSSGKPARAEAKKRYQKAYAASLNVQESLAE................ 576
2 -120.0005ey9_A mol:protein length:629 Long-chain-fatty-acid--AMP ligase FadD32  ali model follow..  26  17.ENTNLVRHVEKWARVRGDKLAYRERDGVERDILWSEFSARNRAVGARLQQVT-QPGDRIAILCPQNLDYLISFFGALYSGRIAVPLFDP----AEPGHVGRLHAVLDDCTPSTILTTTDSAEGVRKF-------IRSRSAKERPRVIAVDAVPTEVASTWQQPEANELTTAYLQYTSGSTRVPSGVQITHLNLPTNVLQVLNALEGQEGDRGVSWLPFFHDMGLITVLLASVL-GHSFTFMTPAAFVRRPGRWIRELARKGGTFSAAPNFAFEHAAMR-GVPRDDEPPLDLSNVKGILNGSEPVSPASMRKFFKAFEPYGLRETAVKPSYGLAEATLFVSTTPMDEVPTVIHVDRDELVSAGKVGVDEWAVIVDLPDGQIGEIWLHGNNLGIGYWGKEEESAQTFDGLWVRTGDYGTYFKGHLYIAGRIKDLVIIDGRNHYPQDLEYTAQESTKLRVGYVAAFSVPEQLVIVGERAAHKLEYQPIADDIRAAIAVGHGVTVRDVLLVSAGTIPRTSSGKIGRRACRTAYIDGSLRSGVSSPTVFATGS............. 629
3 -120.0003kxw_A mol:protein length:590 Saframycin Mx1 synthetase B  ali model follow..  26  9.QCQSLVDVVRLRALHSPNKKSCTFNKELEETMTYEQLDQHAKAIAATLQAEGAKPGDRVLLLFAPGLPLIQAFLGCLYAGCIAVPIYPPAQ----EKLLDKAQRIVTNSKPVIVLMIADHIKKFTADELNTNPKFLKI------PAIALESIELNRSSSWQPTSIKSNDIAFLQYTSGSTMHPKGVMVSHHNLLDNLNKIFTSFHMNDETIIFSWLPPHHDMGLIGCILTPIYGGIQAIMMSPFSFLQNPLSWLKHITKYKATISGSPNFAYDYCVKRI--REEKKEGLDLSSWVTAFNGAEPVREETMEHFYQAFKEFGFRKEAFYPCYGLAEATLLVTGGTPGSSYKTLTLAKEQFVSSGNP--IQEVKIIDCDFDQVGEIWVQSNSVAKGYWNQPEETRHAFSAIYLRTGDLGFLHENELYVTGRIKDLIIIYGKNHYPQDIEFSLMHSPLHVLGKCAAFVIQYKLTVMCEVKNDDVAQDNLFNEIFELVYENHQLEVHTIVLIPLKAMPHTTSGKIRRNFCRKHLLDKTLPIVATWQLNKIEEG............. 584
4 -119.0005hm3_A mol:protein length:657 Long-chain-fatty-acid--AMP ligase FadD32  ali model follow..  26  39.ANTNLVRHVEKWAKVRGDKLAYRERDGVARDILWSDFSARNRAVGARLQQVT-QPGDRVAILCPQNLDYLISFFGALYSGRIAVPLFDPAE----PGHVGRLHAVLDDCAPSTILTTTDSAEGVRKF-------IRARSAKERPRVIAVDAVPTEVAATWQQPEANEETVAYLQYTSGSTRIPSGVQITHLNLPTNVVQVLNALEGQEGDRGVSWLPFFHDMGLITVLLASVL-GHSFTFMTPAAFVRRPGRWIRELARKGGTFSAAPNFAFEHAAVR-GVPRDDEPPLDLSNVKGILNGSEPVSPASMRKFFEAFAPYGLKQTAVKPSYGLAEATLFVSTTPMDEVPTVIHVDRDELVSAGKVGVSEWAVIVDLPDGQIGEIWLHGNNLGTGYWGKEEESAQTFDALWVRTGDYGTYFKDHLYIAGRIKDLVIIDGRNHYPQDLECTAQESTKLRVGYAAAFSVPEQLVIVGERAAHKLDHQPIVDDIRAAIAVGHGVTVRDVLLVSAGTIPRTSSGKIGRRACRAAYLDGSLRSGVGSPTVFATS.............. 650
5 -119.0005icr_A mol:protein length:650 Acyl-CoA synthase  ali model follow..  25  31.DGSSIVAHVERWAKVRGDKLAYRERDGVPRDLTWAQFSARNRAVAARLQQVT-QPGDRVAILCPQNLDYLVAFFGALYAGRIAVPLFDPSE----PGHVGRLHAVLDNCHPSAILTTTEAAEGVRKF-------FRTRPANQRPRVIAVDAVPDDVASTWVNPEPDETTIAYLQYTSGSTRIPTGVQITHLNLATNVVQVIEALEGEEGDRGLSWLPFFHDMGLITALLAPMI-GHYFTFMTPAAFVRRPERWIRELARKEGTISVAPNFAFDHAAAR-GVPKPGSPPLDLSNVKAVLNGSEPISAATVRRFNEAFGPFGFPPKAIKPSYGLAEATLFVSTTPSAEEPKIITVDRDQLASAGKVGIAEWAVIVDLPDGQVGEIWISGQNMGTGYWGKPEESVATFDATWVRTGDYGAFYDGDLYITGRVKDLVIIDGRNHYPQDLEYSAQEASKIRTGYVAAFSVPEQLVIVAERAPHKLDIGPITDDIRAAIAVRHGVTVRDVLLTAAGAIPRTSSGKIGRRACRAAYLDGSLRAGKVANDFPDAT.............. 643
6 -112.0004r0m_B mol:protein length:643 McyG protein  ali model follow..  20  15.NWRTLSEVLETATKHNNHGITYIRNDATEYFQSYQDLYQDALVILNGLEQKGIKLGHKVILQIAKNQDFIPALWACFLGGIIPVPLTVAPSYDLENSAVKKLENVWKILDNPLILSDSELITEI--------EKLGTYSHLEGWQVISVNELRKAPSKIEQLPILDPQDAALLLFTSGSTGMPKGVILTHHNILSMTAGTVVMNHFTQQEVTLNWMPLDHVGAIVFLGIMAVDLACDQIHVPMELVLRQPLQWLELIQKHQVSISWSPNFAFSLINQQA--EELKHVSYNLSSMKFLVNAGEQVSVKTIRLFLEILEKHQLQERAIKPAFGMTESCSGITWSAGLSKNELT--EENSFVSLGKPIPGATIRIVDLPEREIGRLQIQGNSVTKGYYNNNELNQEVFQEGWFTTGDLGYLSKGELFITGREKQEIIINGVNYFAHELETTIEELEGVKVSYTAAFAVFDQIITFSPESEQFEQGIKVVRKIRSHVTQKFGIAPAYVIPLERNLVPKTSIGKVQKSKLKKDFEQGLFSSRIQEIDQYLAKERQKNQTLPQSENE 575
7 -92.5003e53_A mol:protein length:480 FATTY-ACID-CoA LIGASE FADD28  ali model follow..  25  16.SVRSLPAALRACARLQPHDPAFTDWDGVAITLTWSQLYRRTLNVAQELSRCGS-TGDRVVISAPQGLEYVVAFLGALQAGRIAVPLSVPQG----GVTDERSDSVLSDSSPVAILTTSSAVDDVVQH-------VARRPGESPPSIIEVDLLDLDAPNGYTFKEDEYPSTAYLQYTSGSTRTPAGVVMSHQNVRVNFEQLMSGYFADTDSALVSWLPFYHDMGLVIGICAPILGGYPAVLTSPVSFLQRPARWMHLMASDFHAFSAAPNFAFELAARRT--TDDDMAGRDLGNILTILSGSERVQAATIKRFADRFARFNLQERVIRPSYGLAEATVYVATSKPGQPPETVDFDTESLISYMLP-RSPIVRIVDCPDGTVGEIWVHGDNVANGYWQKPDESERTFEGPWLRTGDSGFVTDGKMFIIGR..................................................................................................................................... 474
8 -91.3005d6n_A mol:protein length:508 Acyl-CoA synthase  ali model follow..  23  35.DGSSIVAHVERWAKVRGDKLAYRERDGVPRDLTWAQFSARNRAVAARLQQVT-QPGDRVAILCPQNLDYLVAFFGALYAGRIAVPLFDPSE----PGHVGRLHAVLDNCHPSAILTTTEAAEGVRKF-------FRTRPANQRPRVIAVDAVPDDVASTWVNPEPDETTIAYLQYTSGSTRIPTGVQITHLNLATNVVQVIEALEGEEGDRGLSWLPFFHDMGLITALLAPMI-GHYFTFMTPAAFVRRPERWIRELARKEGTISVAPNFAFDHAAAR-GVPKPGSPPLDLSNVKAVLNGSEPISAATVRRFNEAFGPFGFPPKAIKPSYGLAEATLFVSTTPSAEEPKIITVDRDQLASAGKVGIAEWAVIVDLPDGQVGEIWISGQNMGTGYWGKPEESVATFDATWVRTGDYGAFYDGDLYITGRV.................................................................................................................................... 502
9 -74.1005jjp_A mol:protein length:543 Nonribosomal peptide synthase  ali model follow..  18  21.HAGNLRDYLLAAGKATPDKPAIVEPAEDLRFVSYRQLEAQADAYAAELDALGLDVGDRVVLESPATADAVAAFLACFSLGLPFIPTIPETPV-------QRLRTIIGMAAPALFLQAADGSREGLPPGLGMAR----------FGPKGVTTEQLPAPRVRRRRQVVETDPAYLIFTSGTTGRPKGVVMSHRANIAFHRGIRAHGLIGPDDRVAVTSPFSFDFC-LGGIALTLASGATAVPV-PRDRLDFPRRFLAFLHEAAITQVHGVPSLWRPLIRHEPDLVA-----GLDPLRSILFSGEDFPLGDLRELQGLLPG-----RRIFNLYGATESMAASVTDVPDPLP-----ADLERLTIGYAHHGAEMDVYDGEPGVVGEIYLRSPALFSGYWADPEATRAALGQVVFRTGDLARDADGRLYFCGRIDSQVQIRGNRVELGEVERRLREFPGVSGAVALVAPAGEG--LSAFLTMRPGAPAPKLVPLRAFCAETLPEYMAPRSLTVLAELPVTTNGKIDKDALLR.................................. 532
10 -73.8003dhv_A mol:protein length:512 D-alanine-poly(phosphoribitol) ligase  ali model follow..  17  1...AKLLEQIEKWAAETPDQTAFVW---RDAKITYKQLKEDSDALAHWISSEYPDDRSPIMVYGHMQPEMIINFLGCVKAGHAYIPVDLSIPA-------DRVQRIAENSGAKLLLSATAVTVTDLPVRIVSEDNLKDIFFTH------------KGNTPNPEHAVKGDENFYIIYTSGSTGNPKGVQITYNCLVSFTKWAVEDFNLQTGQVFLNQAPFSFDLSVM-DIYPSLVTGGTLWAIDK-DMIARPKDLFASLEQSDIQVWTSTPSFAEMCLMEASFSESM-----LPNMKTFLFCGEVLPNEVARKLIERFPKA-----TIMNTYGPTEATVAVTGIHVTE----EVLDQYKSLPVGYCKSDCRLLIMKAPDGEKGEIVIVGPSVSVGYLGSPELTEKAFGERAYKTGDAGYVENGLLFYNGRLDFQIKLHGYRMELEEIEHHLRACSYVEGAVIVPIKKGEKLAVVVPGEHSFEKEFKLTSAIKKELNERLPNYMIPRKFMYQSSIPMTPNGKVDRKKLLS.................................. 500
11 -73.7005jjq_A mol:protein length:552 AMP-dependent synthetase and ligase  ali model follow..  18  25NPVERLHEFLLTGARLTPEKPAVLELSGEPGYVSYRQLANRAESYAAALGGLGLDIGDRVVLESDTSASAIAALLACSSLGLPFVPVTPETPA-------KRLLAVVDTVSPALYLQAEGGRREG----------LPESVGTGRFGPGGLVIERAPRPGRGFRREVAPADPAYMVFTSGSTGRPKGVVMSHRAILSFYRGMLSQGIVGPESRVASTAPFQFDFS-LLDIGLALGSGATVVPV-PRALLRWPRRFVRFLRDSEATQVNGAPSIWRGALRHEADELAALG----GRIRGVLFSGEPFPLPEVRALQQALPLA-----RIVNCFGSTESVAASFTDVPRPVP-----DGLTKLSIGHAHPGAEMMLLDTEPGVTGHIHLRSGSLFTGYWGDPEATARALGQTVFRTGDLARDATGELYFDGRADNQVKIRGNRVELTEVERRVAEFTGVAAASAVLLPVAESDPVLAVFVELSPGAEFDEMELGAFCLEELPDYMAPQRIHVLDALPLNQNGKVDRPALVE.................................. 536
12 -73.3003wvn_A mol:protein length:541 Non-ribosomal peptide synthetase  ali model follow..  17  37.YGGLVHDLLADSGKATPNSDAMED---AFGTWTYQELLNHSQAFSAWLDGKGVARGERIVVQLPNIRQTVAVFYGACRRGVVFVPLNPGMKP-------FHLRSVIADADPRLVIAEDETAADR-------LRDVTDLPVYSIDSLWADVERLRDAGAGAEAVEVSPEDLAVLIYTSGSTAAPKAVACPHQQIVFAASSINAVLGYHAEDIVFCRMSVSWDFGLY-KVLISTLTGAKLVLAGG----EPDIALVKSLRESGATMMPIVPSLASMLTTLIRRDPE-----GAPTLRMFTNSAAALPQVTIDALRSAFPGA-----QVVRMYGQTECKRISIMPP--------HLEHERPDSVGLPLPGTTIEILDLPPGEPGEITVTGPHVMAGYWRAPEITARAYGAMRLHTGDYGHLEDGFLYFGGRRDDMFKRKGTRMSTVEIEAAALDIPGVTAAVALPPTATRDLALCV---ASDLEPHDVLRSLAERLEPA--KVPATCRIV--NDFPLTLNGKSERKQLARLLDGSD............................ 534
13 -72.2003l8c_A mol:protein length:521 D-alanine--poly(phosphoribitol) ligase subunit 1  ali model follow..  15  1MSLKDMIDSIEQFAQTQADFPVYDC---LGERRTYGQLKRDSDSIAAFIDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAP-------ERILAIIEIAKPSLIIAIEEFPLT--------------IEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPKGVQISHDNLLSFTNWMIEAFDVPKQPQMLAQPPYSFDLSVM-YWAPTLALGGTLFAL-PKELVADFKQLFTTIAQLPVGIWTSTPSFADMAML-----SDDFCQAKMPALTHFYFDGEELTVSTARKLFERFPSA-----KIINAYGPTEATVALSAIEITR----EMVDNYTRLPIGYPKPDSPTYIIDLSSGEQGEIIVTGPAVSKGYLNNPEKTAEAFGQPAYHTGDIGLTEDNILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHIVVKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLIN.................................. 508
14 -71.8003e7w_A mol:protein length:511 D-alanine--poly(phosphoribitol) ligase subunit 1  ali model follow..  17  2....KLLHAIQTHAETYPQTDAFRS---QGQSLTYQELWEQSDRAAAAIQKRISEKKSPILVYGHMEPHMIVSFLGSVKAGHPYIPVDLSIPS-------ERIAKIIESSGAELLIHAAGLSIDAVGQQIQTVS--------------AEELLENEGGSVSQDQWVKEHETFYIIYTSGSTGNPKGVQISAANLQSFTDWICADFPVSGGKIFLNQAPFSFDLSVM-DLYPCLQSGGTLHCVTK-DAVNKPKVLFEELKKSGLNVWTSTPSFVQMCLM-----DPGFSQDLLPHADTFMFCGEVLPVSVAKALLERFPKA-----KIFNTYGPTEATVAVTSVEITN----DVISRSESLPVGFAKPDMNIFIMDLPEGEKGEIVIAGPSVSRGYLGEPELTEKAFGQWAYRTGDAGFIQDGQIFCQGRLDFQIKLHGYRMELEEIEFHVRQSQYVRSAVVIP-TVEYLIAAIVPEEHEFEKEFQLTSAIKKELAASLPAYMIPRKFIYQDHIQMTANGKIDRKRIGEEVLVRS............................ 505
15 -71.8005n9w_A mol:protein length:529 Adenylation domain  ali model follow..  21  16.FGATLVDLFSRAAMEMPDRTALHI---DDEKISYGLLHSWAEGLADLLHDAGVRKGDRVALRMPPGANAIAAMLGILRAGAAYVPLDIRNPP-------ARNAFIVTDSQVVALVGDPGDIPEYTGPLVTEEN--------------VAALRDREAIKDPGPERPGPQDVAYIIYTSGTTGRPKGVPVRHGNVTALFEACSRLFSFSADDRWLLFHSMAFDFS-VWEIWGALSTGAELVVL-PYWTARTPVETARVVRDRGITVLNQTPTAFGALTTAVLGEGI-----DLPELRYVVFGGEKLTPAVVRPWAKRF---GLDRPHLINMYGITETTVHATFHRLTEDDL-----AAEDSVIGRPLPGFTHRIVTAATGEPGELWLAGPQVSEGYLNRPELTAERFPPRYYHSGDLVRRAGGDLVYQGRADLQVKLRGHRIELSDVEAAVRTHPAVVDAVVWV-PGDSRLVCAYTAQASEEGTGPDARALRAHVKTVLPSYMQPSQYLALPELPRTINGKADRASVAR.................................. 523
16 -71.6003vnq_A mol:protein length:544 NRPS adenylation protein CytC1  ali model follow..  21  27.RNSDLVSLFREVAATAPERTALSA---EDDRISYGRLDAWSDAVARTLLAEGVRPGDRVALRMSPGAEAIVAILAILKCGAAYVPVDLRNPV-------SRSDFILADSGASALIGEPHEGCAVTRVVRTAA---------------VAECKDAEPGPVTGAPGPGAEDMAYVIYTSGTTGNPKGVPVRHANVLALLAGAPSVFDFSGDDRWLLFHSLSFDFS-VWEIWGAFSTGAELVVL-PHWAARTPEQYLAVIIDRGVTVINQTPTAFLALTEAAVRGGR-----DVSGLRYVIFGGEKLTAPMLRPWAKAF---GLDRPRLVNGYGITETTVFTTFEEITEAYL-----AQDASIIGRALPSFGTRVVGVAPGETGELWLSGAQLAEGYLRRPELTAEKFSVRYYRTGDLVELPDGRFAYEGRADLQIKLRGYRIELSDIETAVRRHDDVVDAVVTVREFKPGDLRLVCAYVAREGSATTARELRNHIKTLLPAYMHPARYLPLPGLPRTVNGKVDRAAVAR.................................. 529
17 -70.6004d4g_A mol:protein length:573 APNAA1  ali model follow..  18  24...QSIHQLFETQVERTPEAVAVLS---EQGQLTYEELNTKANQLAHYLRTLGVKSETLVGVCVDRSLEMVIGLLAILKAGGAYVPLDPTYPR-------ERLTYMVQDAQISVLVTQTQWSNLISDYQGQVICLDSQWAKIAS------------YSQENLVNTVNPENLAYVIYTSGSTGKPKGVMIEHQSLVNFTKLAIAQYQITTSDRTLQFVSISFDVA-AEEIYVTLCSGATLILRTE-EMISSIPSFVQKSQDWQITVWSLPTAYWHLLVNELVKSKIAL----PDSLRLVIIGGERVQPELVRMWFKNVG----NFPELINVYGPTEGTIAVSLCRLSQL--TESQRNRTEIPIGKSLENISVYVLDVPPETPGEIYIGGTALARGYLNRPELTAQKFSERLYKTGDLGYLADGNLEYLGRVDHQVKINGFRVELGEIETVLLQHHQVAQAVVID-LGNKRLVAYLVPHSTEENLTVTLQQFLKNKLPSYMIPATFVVL---NELPLSPNGKIDRKAL.................................... 526
18 -69.6005ie0_A mol:protein length:514 Oxalate--CoA ligase  ali model follow..  19  1MDSDTLSGLLENVAKKFPDRRALSV--SGKFNLTHARLHDLIERAASRLSDAGIKPGDVVALTFPNTVEFVIMFLAVIRARATAAPLNAAYTA-------EEFEFYLSDSDSKLLLTSKEGNAPAQEAASKKISHVTATLLDAGSDLVLSVADSDSVVDSATELVNHPDDGALFLHTSGTTSRPKGVPLTQLNLASSVKNIKAVYKLTESDSTVIVLPLFHVHGLLAGLLSSLGAGAAVTLPAAGRF--SATTFWPDMKKYNATWYTAVPTIHQIILDR----HASHPETEYPKLRFIRSCSASLAPVILSRLEEAFG-------PVLEAYAMTEATHLMSSNPLPEE------GPHKPGSVGKPV-GQEMAILNQEPNNKGEVCIRGPNVTKGYKNNPEANKAGFEFGWFHTGDIGYFTDGYLHLVGRIKELINRGGEKISPIEVDAVLLTHPDVSQGVAFGVP-EEINCAVIPREGTTVTEEDIKAFCKKNLAA-----PKRVFITD--NLPKTASGKIQRRIVAQHFLE.............................. 512
19 -69.3004oxi_A mol:protein length:576 Enterobactin synthetase component F-related protein  ali model follow..  15  47......RHSILAAIQANRHAPALWV---KQKTYTYQEMTDMALSLSDYWHLQGVQR---VAILSVRDLAAYSAIWASYLGGMTYIPLNARATT-------EQIQETLIATQCDSIMVDAQQLSRLSSLLETCIDRLHIYAYPQHTFHTVQITEQDVELLVVKYHLDNEHEYAYIMQTSGSTGKPKRIAVSYSNLHCYISQIDKLFPLNAQDRVGQYSDLTFDLS-VHDIFYSLISGACLYVVPELAKLS-----AEFIHHHQLTVWLSVPTVIELALQR-----QTLTPHSLPSLRLSFFCGQALLHDLAEQWQQA------TQQPVINLYGPTECTIAVTYHR------FVAHSGMASVPIGRAFEEECLAIINAPEGYRGELLLSGKQLVKGYLNDPLNTQSAFGRLWYRSGDIVTKSNGVLIHLGRRDHQVKIAGQRVELEEIETVVRRVTQAHSVAIVPWPLSES-TVAFVDTHTQWQPDLWLSQCKQQLNPT--FVPKRWYAIE--QLPRNANGKTDIKALQQQLASQTYET......................... 568
20 -69.0005wmm_A mol:protein length:926 NRPS  ali model follow..  17  46.VVGTIPERFAAVVAEQPEAVALVA-ADGEESWTYGELDRWANRIAHHLHARGVGRQHRVALVMERSPLLVAAVLGTLKAGACYVPVEPTWPR-------ARIDLVLADLDPALVIDERLAEEDLTGYPTRPL----------------------------DTADVGGEHLAYLMYTSGSTGTPKGVEVSHRNVLS--LALDPCWADADHQRVLVHAPPTFDAS-TYEMWVPLLHGGAAVVAPPGK--LDAARLATLIAERGVTALWLPAGLFDLITQHHPKS--------FVQVREVWAGGDVLSPAAVRRLVRDDGT-----LTVVNGYGPTETTTFAARYRMSAP-----ARCKDPLPIGEPMAGSRLYALDVPQGVIGELYVGGDGVARGYANHPPLTSERFGERMYRTGDLVWNHDGQLEFLGRVDEQVKIRGFRVEPGEIRAALRKRDGVAQAVVVP-LGERRLVAYVVPEVPAGADEDSTEHVEK---RAIYDSMYDETEADATEIGNDFTGWKSS....................................... 523
21 -68.9002v7b_A mol:protein length:529 BENZOATE-COENZYME A LIGASE  ali model follow..  18  24....NFAAYLFRLNETRAGKTAYID---DTGSTTYGELEERARRFASALRTLGVHPEERILLVMLDTVALPVAFLGALYAGVVPVVANTLLTP-------ADYVYMLTHSHARAVIASGALVQNVTQALESAEHDGCQLIVSQPREAPLFEELIDAAAPAAKAAATGCDDIAFWLYSSGSTGKPKGTVHTHANLYWTAELYAKPLGIAENDVVFSAAKLFFAYGLGNGLTFPLSVGATAILMAER----TADAIFARLVEHRPTVFYGVPTLYANMLVS-----PNLPARADVAIRICTSAGEALPREIGERFTAHFG-------EILDGIGSTEMLHIFLSNRAGA---------VEYGTTGRPVPGYEIELRDVPDGEVGDLYIKGPSAAVMYWNNREKSRATFLGEWIRSGDKYCRPNGCYVYAGRSDDMLKVSGQYVSPVEVEMVLVQHDAVLEAAVVGVDHGVKTRAFVVLKREFAPSEILAEELKAFVKDRLAPHKYPRDIVFVDDLPKTATGKIQRFKLREQ................................. 529
22 -68.5004wv3_A mol:protein length:529 Anthranilate-CoA ligase  ali model follow..  15  11....NAVDILERNLPVRANKTALFT---PDREMTFRQVSNEANQVGNALKGLGVRFGECVGLLTLDSAEWVTSFFGIVKLGAIAVGINTLLKP-------PEYEYILRDCRARVLIVHQEFLPLIESIRGPMLEHIVVIGEGPQEGYLSFNDWIRPQPTTLEAAQSHREDICSLNYSSGTTGGPKGIPHAHKDYPLTAQLWGVNLGLRESDRTFALAKLFFTFGTGGNLIFPWYVGASCVLFPGAAR--VASNVLSTISRFKPTIFYNAPTGYAAALAL-----KDFSQHDLSSLRLCVSASEALPAALWYAWKEATG-------DIIDGIGCTENFHIFISNRPGD---------IRPGSSGKPVEGYELKLVDVPAGEIGNVLLRSETAALSYWHNFEKSRQTFQGEWLATGDKYFVADGYYWHAGRSDDMLKVGGIWVSPVEVESTLIQHPAVQECAVIGCPDQIKPKAFIILKPEQIPSEALIRQITDHCTEKMAAYKRPRWIEFVTELPKTATGKIQRFKLRSAAKLAA............................ 520
23 -68.3004eat_A mol:protein length:524 Benzoate-coenzyme A ligase  ali model follow..  17  14....NFAEHLLQTNRVRPDKTAFVD---DISSLSFAQLEAQTRQLAAALRAIGVKREERVLLLMLDGTDWPVAFLGAIYAGIVPVAVNTLLTA-------DDYAYMLEHSRAQAVLVSGALHPVLKAALTKSDHEVQRVIVSRPAAEVDFAEFVGAHAPLEKPAATQADDPAFWLYSSGSTGRPKGVVHTHANPYWTSELYGRNLHLREDDVCFSAAKLFFAYGLGNALTFPMTVGATTLLMGERP--AVFKRWLGGVGGVKPTVFYGAPTGYAGMLAA-----PNLPSRDQVALRLASSAGEALPAEIGQRFQRHFG-------DIVDGIGSTEMLHIFLSNLPDR---------VRYGTTGWPVPGYQIELRGVADGEPGDLYIHGPSSATMYWGNRAKSRDTFQGGWTKSGDKYVRDDGSYTYAGRTDDMLKVSGIYVSPFEIEATLVQHPGVLEAAVVGVADEHGKAYVVPRPGQTLSETELKTFIKDRLAP-----PRSTVFVA--ELPKTATGKIQRFKLREGVLG.............................. 524
24 -68.2003g7s_A mol:protein length:549 Long-chain-fatty-acid--CoA ligase (FadD-1)  ali model follow..  16  16YPKISLADRIDAAAEKFGEKTAIISAEPKPESMNFLEICEVTKKLASGISRKGVRKGEHVGVCIPNSIDYVMTIYALWRVAATPVPINPMYKS-------FELEHILNDSEATTLVVHSMLYENFKPVLEKT--GVERVFVVGGEVNSLSEVMDSGSEDFENVKVNPEEDVALIPYTGGTTGMPKGVMLTHFNLAANALQLAVATGLSHMDTIVGCMPMFHSAEF-GLVNLMVTVGNEYVVMGM-----NQEMLAENIEKYKGTFSWAVPPALNVLVNT---LESSNKTYDWSYLKVFATGAWPVAPALVEKLLKLAAECNNPRLRHNQIWGMTEACPMVTTNPPL--------RLDKSTTQGVPMSDIELKVISLGVGESGEIVIRGPNIFKGYWKREKENQECWGRKFFRTGDVGFIEEGFLHFQDRVKEVIKYKGYTIAPFELEALLMKHEAVMDVAVIGKPDEEAFIVLKPEYRGKVDEEDIIEWVRERISGYKRVREVEFV----EELPRTASGKLLRRLLREKEAEG............................. 543
25 -68.2004gr5_A mol:protein length:570 Non-ribosomal peptide synthetase  ali model follow..  19  73.AGACVHELFEAQAARAPDAVALLH---EADELTYGALNERANRLAHRLVGLGVAPGTLVGVHLERGFDMVVALLAVLKAGGGYTMLDPQFPV-------ERLALSLEDTGAPLLVTSRPLSGRLTGTTTLYVE----------------DEAASDAPAGNLATGVGPEDVACVMFTSGSTGRPKGVMSPHRALT-GTYLGQDYAGFGPDEVFLQCSPVSWDAF-GLELFGALLFGARCVLQSGQN--PDPLEIGELVARHGVTMLQLSASLFNFLVDEVPEA--------FEGVRYAITGGEPASVPHVAKARRDHPAL-----RLGNGYGPAESMGFTTHHAVVAG-----DLSGTALPIGVPLAGKRAYVLDAANGALGELYVAGAGLAHGYVSRPALTAERFGERMYRTGDLARRADGVLEYVGRADDQVKIRGFRVEPGEVEARLVGHPAVRQAAVLAQDSRLG--LVAYVVAERADAPPDAAELRRHVAEALPAYMVPVECVPVDELPRTPNGKLDRRAL.................................... 565
26 -68.1005es5_A mol:protein length:776 Linear gramicidin synthetase subunit A  ali model follow..  20  203...KTFHQLFEQQVEMTPDHVAVVD---RGQSLTYKQLNERANQLAHHLRGKGVKPDDQVAIMLDKSLDMIVSILAVMKAGGAYVPIDPDYPG-------ERIAYMLADSSAAILLTNALHEEKANGACDI---------------IDVHDPDSYSENTNNLPHVNRPDDLVYVMYTSGSTGLAKGVMIEHHNLVNFCEWYRPYFGVTPADKALVYSSFSFDGS-ALDIFTHLLAGAALHIVPSER-KYDLDALNDYCNQEGITISYLPTGAAEQFMQM-----------DNQSFRVVITGGDVLKKIERNGTYK-----------LYNGYGPTECTIMVTMFEVDK--------PYANIPIGKPIDRTRILILDQPIGVAGELFIVGEGLGRGYLNRPELTAEKFGERMYRTGDRAFLPDGNIEFLGRLDNLVKIRGYRIEPGEIEPFLMNHPLIELTTVLA-ADGRKYLVGYYVAPEEIPHGELREWLGNDLPD-YMIPTYFVHM---KAFPLTANGKVDRRALPD.................................. 680
27 -67.5004ir7_A mol:protein length:541 Long chain fatty acid CoA ligase FadD10  ali model follow..  18  14..PSTVLDRVFEQARQQPEAIALRR-CDGTSALRYRELVAEVGGLAADLRAQSVSRGSRVLVISDNGPETYLSVLACAKLGAIAVMA-------DGNLPIAAIERFCQITDPAAALVAPGSKMASSAVPEALHSIPVIAVDIAAVT--RESEHSLDAASLAGNADQGSEDPLAMIFTSGTTGEPKAVLLANRTFFAVPDILQKEVTWVVGETTYSPLPATHIGGL-WWILTCLMHGGLCVTGG------NTTSLLEILTTNAVATTCLVPTLLSKLVSE-----LKSANATVPSLRLVGYGGSRAIAADVRFIEAT---------RTAQVYGLSETGCTALCLPTDDG----SIVKIEAGAVGRPYPGVDVYLAAGPSASFGTLWIKSPANMLGYWNNPERTAEVLIDGWVNTGDLLEREDGFFYIKGRSSEMIICGGVNIAPDEVDRIAEGVSGVREAACYEIPDEEGLAVVASAELDESAARALKHTIAARFRRESEPMARPSTIVIVTDIPRTQSGKVMRASLAAAATADKARVVV....................... 539
28 -67.4004iz6_A mol:protein length:635 Enterobactin synthase component E, Isochorismatase  ali model follow..  15  38.QDLPLTDILTRHA--ASDSIAVI---DGERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVLALFSHQRS-------ELNAYASQIEPALLIADRQHADDFLNTFVTEHSSIRVVQLLNDSGEHNLQDAINHPAEDFTATPSPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEICQFTQQTRYLCAIPAAHNYAMSPGSLGVFLAGGTVVLAAD-----SATLCFPLIEKHQVNVTALVPPAVSLWLQALI---EGESRAQLASLKLLQVGGARLSATLAARIPAEIG-------QLQQVFGMAEGLVNYT--------RLDDSAEKIIHTQGYPMPDDEVWVADLPQGEVGRLMTRGPYTFRGYYKSPQHNASAFANGFYCSGDLISIPEGYITVQGREKDQINRGGEKIAAEEIENLLLRHPAVIYAALVSMEDELEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVECV---DSLPLTAVGKVDKKQLRQWLASRASAGRASIPASKAALREVILPLLDESDE. 576
29 -67.1003o82_A mol:protein length:544 Peptide arylation enzyme  ali model follow..  15  28.IDQPLTRILTVGVQSHPHSLAII---CGERQLSYIELDRLSTNLATRLAEKGLGKGDTALVQLPNVAEFYIVFFALLKAGVVVLNALYSHRQY-------ELNAFIKQIQPKLLIGSRQHEVFSNNQFIDSLHDVNLMLNHQATDFGLLDWIETPAETFVDFSSTPADEVAFFQLSGGSTGTPKLIPRTHNDYDYSVRASAEICGLNSNTRLLCALPAPHNFMLSPGALGVLHAGGCVVMAPN-----EPLNCFSIIQRHQVNMASLVPSAVIMWLEK-----AAQYKDQIQSLKLLQVGGASFPESLARQVPEVLN-------KLQQVFGMAEGLVNYT--------RLDDSDEQIFTTQGRPISSDEIKIVDVPEGEIGMLATRGPYTFCGYYQSPEHNSQVFEDNYYYSGDLVQRPDGNLRVVGRIKDQINRGGEKIASEEIEKLILLHPEVMHAALVAIVDEEKSCAFIVSRNPELKAVVLRRHLMELGIAQYKLPDQIKLI---ESLPLTAVGKVDKKQLRSILNTST............................ 542
30 -66.9005upq_A mol:protein length:525 Acyl-CoA synthetase PtmA2  ali model follow..  17  4LQHTTIGDVLREHRRSHPGRTALVD---GPVRLTWPELDDRVNRLAGSLAASGIGRGDRIMWLGQNSFRVYELIAAAGKLGAMVCVG-------YWRWAPPEMEFALRDFDPHLVVWQHQEIHETVARTREALGSDDTAHDSAPQDPDGYEAFLAAGGLADPDLDIDPDSPVLVLYTAAMSGRQCGSLLSHTNLIAMATAAAWLGDIDHTTAFLNSGPMFHIGNHQFWGMPTLLMAGKNVIVRRV----VAEEVRDLLVAEECTHAFLMPPTVAEIVRL-----NRDTGHDLSRLRATVAPHLWEGMATTDTSRFTRSGA-----AAGRGYGQTELSGFAV---------TAAYGGPAAGNAGRPGPGLTVRVLDCAVGEAGEICARGTVVHRGYWNRDEVNAHRFRSGWWHTTDLGRRPDGSLTFLGTTTRMLKSAAENIFPAEVENCIEQHPAVRE--AAVIGVPNTKAVVVLEPDAGVSEQEIIDHCRPRIAS----KPKSVAFA--AALPRTVSGARDYDALDKEYGGGGYPGAAT...................... 520
31 -66.7002vze_A mol:protein length:570 ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL  ali model follow..  15  42........ADMEKAGKRPPSPALWWVNGKELMWNFRELSENSQQAANVLSACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTD-------ILYRLQMSKAKAIVAGDEVIQEVDTVASESLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKF--DPLVILKTLSSYPIKSMMGAPIVYRMLLQ------QDLSSYKFPHLQNCVTVGESLLPETLENWRAQTG-------DIRESYGQTETGLTCMVSKTMK---------IKPGYMGTAASCYDVQIIDLPPGTEGDIGIRVKGIFSGYVDNPDKTAANIRGDFWLLGDRGIKEDGYFQFMGRADDIINSSGYRIGPSEVENALMEHPAVVETAVISSPDPVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRAKLRDKEWKMSGKARAQ...................... 564
32 -66.7001amu_A mol:protein length:563 GRAMICIDIN SYNTHETASE 1  ali model follow..  15  39...KTIHQLFEEQVSKRPNNVAIVC---ENEQLTYHELNVKANQLARIFIEKGIGKDTLVGIMMEKSIDLFIGILAVLKAGGAYVPIDIEYPK-------ERIQYILDDSQARMLLTQKHLVHLIHNI------------QFNGQVEIFEEDTIKIREGTNLHVPSKSTDLAYVIYTSGTTGNPKGTMLEHKGISNLKVFFENSLNVTEKDRIGQFASISFDAS-VWEMFMALLTGASLYIILKDT-INDFVKFEQYINQKEITVITLPPTYVVHLDPE-----------RILSIQTLITAGSATSPSLVNKWKEKVT--------YINAYGPTETTICATTWV------ATKETIGHSVPIGAPIQNTQIYIVDKSVGEAGELCIGGEGLARGYWKRPELTSQKFGEKLYKTGDQAWLSDGNIEYLGRIDNQVKIRGHRVELEEVESILLKHMYISETAVSV-HQEQPYLCAYFVSEKHIPLEQLRQFSSEELPT-YMIPSYFIQL---DKMPLTSNGKIDRKQ---------LPEPDLTFGMRVDYEAPRNEIEETLVT. 549
33 -66.4005bsm_A mol:protein length:542 4-coumarate--CoA ligase 2  ali model follow..  19  26....PLHSYCFENISEFSSRPCLING-ANKQIYTYADVELNSRKVAAGLHKQGIQPKDTIMILLPNSPEFVFAFIGASYLGAISTMANPLFTP-------AEVVKQAKASSAKIIVTQACHVNKVKDYAFENDVKIICIDSAPE-GCLHFSVLTQANEHDIPEVEIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDNLYIHSEDVMLCVLPLFHIYSLNSVLLCGLRVGAAILIMQK-----DIVSFLELIQRYKVTGPFVPPIVLAIA------KSPMVDDYDLSSVRTVMSGAAPLGKELEDTVRAKFPNA-----KLGQGYGMTEAGPVLAMCLAFA----KEPFEIKSGACGTVVRNAEMKIVDLPRNQSGEICIRGDQIMKGYLNDPEATARTIKEGWLYTGDIGYIDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDEQAVAFVVRSNGSTITEDEVKDFISKQVIFYKRIKRVFFV----DAIPKSPSGKILRKDLRAKLAAG............................. 539
34 -66.4004gxq_A mol:protein length:506 Malonyl CoA synthetase, Benzoate-CoA ligase Chimeric protein  ali model follow..  21  8.........RLFDKLDDPHKLAIETA--AGDKISYAELVARAGRVANVLVARGLQVGDRVAAQTEKSVEALVLYLATVRAGGVYLPLNTAYTL-------HELDYFITDAEPKIVVCDPSKRDGIAAIAAKVGATVETLGPDGRGSL---TDAAAGASEAFATIDRGADDLAAILYTSGTTGRSKGAMLSHDNLASNSLTLVDYWRFTPDDVLIHALPIYHTHGLFVASNVTLFARGSMIFLPK-----DPDKILDLMA--RATVLMGVPTFYTRLLQS-----PRLTKETTGHMRLFISGSAPLLADTHREWSAKTG------HAVLERYGMTETNMNTSNPYDGD---------RVPGAVGPALPGVSARVTDLPRGDIGMIEVKGPNVFKGYWRMPEKTKSEFDDGFFITGDLGKIERGYVHILGRGKDLVITGGFNVYPKEIESEIDAMPGVVESAVIGVPHAEGVTAFVVLKREFAPSEILAEELKAFVKDRLAKFKMPKKVIFVDDLPRNTMGAVQKNVLRETYKDI............................. 504
35 -66.3005wm2_A mol:protein length:564 Salicylate-AMP ligase  ali model follow..  19  36WEGRPLDRLLRERAAADPDRIALVDA--AGDRWTYAELDRHADRQAAGLRRLGIGAGDRVVVQLPNTDAFVVLFFALLRAGAVPVLTLPAHRES-------EIVHVAETAGATAYVIPDVLDRALARAARKAVPSIEHVLVAGEAA--EFTALADVDAAPVPLAEPDPGDVALLLLSGGTTGKPKLIPRTHDDYTYNVRASAEVCGFDSDTVYLVVLPTAHNFALCPGLLGTLMVGGTVVLAPT-----SPEDAFELIEREKVTATAVVPPVALLWLDA-----VEWEDADLSSLRLLQVGGSKLGAEPAARVRPALG-------TLQQVFGMAEGLLNYT--------RLDDPSDLVIQTQGRPLPDDEIRVVDVAPGETGELLTRGPYTLRGYYRAPEHNARTFDDGFYRTGDLVRVPSGHLVVEGRAKDQINRGGDKISAEELENHIMAHPGVHDAAVVGMGERTCACLVPRAGRSAPAQRELAAFLTDRGVAAYKLPDRVEVM---DAFPRTSVGKTDKKELGRRIAGQ............................. 549
36 -66.3005kei_A mol:protein length:558 2,3-dihydroxybenzoate-AMP ligase  ali model follow..  18  43.RDQLLDSVLRTAARTWPDHIAVI---DADHRHTYAELDRLADRAAAGIAGLGIRPGDRVLVQLPNTAEFAVALFGLLRAGAVPVMCLPGHRLA-------ELTHFAEVSSAVALVVADTHRDLARELVRSHPDVRHVLVDGDAAEFLSWAEVTRAAPGPVPEIAPDPAAPALLLVSGGTTGAPKLIPRTHQDYVYNATASAELCRLTADDVYLVALPAAHNFPLCPGLLGAMTVGATTVFTTD-----SPEAAFAAIDEHGVTATALVPALAKLWAQA-----CAWEPLAPKTLRLLQVGGAKLAAPDAALVRGALT-------GLQQVFGMAEGLLNYT--------RIGDPPEVLENTQGRPLPDDEIRIVDVPPGAEGELLVRGPYTLNGYFNAEAANERSFPDGFYRSGDRVRRFAGYLEVTGRIKDVIVRGGENVSALDLEEHLLTHPSVWAAAAVALPDEEKICAVVVFNGPPVSLAELHAHLEQRGVAAHSRPDALVPM---PSLPTTAVGKIDKKAIVRQL................................ 556
37 -66.3004fuq_A mol:protein length:503 Malonyl CoA synthetase  ali model follow..  22  8.........RLFDKLDDPHKLAIETA--AGDKISYAELVARAGRVANVLVARGLQVGDRVAAQTEKSVEALVLYLATVRAGGVYLPLNTAYTL-------HELDYFITDAEPKIVVCDPSKRDGIAAIAAKVGATVETLGPDGRGSL---TDAAAGASEAFATIDRGADDLAAILYTSGTTGRSKGAMLSHDNLASNSLTLVDYWRFTPDDVLIHALPIYHTHGLFVASNVTLFARGSMIFLPK-----DPDKILDLMA--RATVLMGVPTFYTRLLQS-----PRLTKETTGHMRLFISGSAPLLADTHREWSAKTG------HAVLERYGMTETNMNTSNPYDGD---------RVPGAVGPALPGVSARVTDLPRGDIGMIEVKGPNVFKGYWRMPEKTKSEFDDGFFITGDLGKIERGYVHILGRGKDLVITGGFNVYPKEIESEIDAMPGVVESAVIGVP-EGVTAVVVRDKGATIDEAQVLHGLDGQLAK-----PKKVIFV--DDLPRNTMGKVQKNVLRETYKDI............................. 501
38 -66.2004gxr_A mol:protein length:503 Malonyl CoA synthetase, Benzoate-CoA ligase Chimeric protein  ali model follow..  22  8.........RLFDKLDDPHKLAIETA--AGDKISYAELVARAGRVANVLVARGLQVGDRVAAQTEKSVEALVLYLATVRAGGVYLPLNTAYTL-------HELDYFITDAEPKIVVCDPSKRDGIAAIAAKVGATVETLGPDGRGSL---TDAAAGASEAFATIDRGADDLAAILYTSGTTGRSKGAMLSHDNLASNSLTLVDYWRFTPDDVLIHALPIYHTHGLFVASNVTLFARGSMIFLPK-----DPDKILDLMA--RATVLMGVPTFYTRLLQS-----PRLTKETTGHMRLFISGSAPLLADTHREWSAKTG------HAVLERYGMTETNMNTSNPYDGD---------RVPGAVGPALPGVSARVTDLPRGDIGMIEVKGPNVFKGYWRMPEKTKSEFDDGFFITGDLGKIERGYVHILGRGKDLVITGGFNVYPKEIESEIDAMPGVVESAVIGVP-EGVTAFVVLKREFAPSEAQVLHGLDGQLAK-----PKKVIFV--DDLPRNTMGAVQKNVLRETYKDI............................. 501
39 -65.9003r44_A mol:protein length:517 fatty acyl CoA synthetase FADD13 (FATTY-ACYL-CoA SYNTHETASE)  ali model follow..  18  11....NIGWMLRQRATVSPRLQAYVEPSTD-VRMTYAQMNALANRCADVLTALGIAKGDRVALLMPNSVEFCCLFYGAAKLGAVAVPI-------NTRLAAPEVSFILSDSGSKVVIYGAPSAPVIDAIRAQADPPGTVTDWIGADSL---AERLRSAAADEPAVECGGDDNLFIMYTSGTTGHPKGVVHTHESVHSAASSWASTIDVRYRDRLLLPLPMFHVAAL-TTVIFSAMRGVTLISMPQ-----DATKVWSLIVEERVCIGGAVPAILNFMRQV-----PEFAELDAPDFRYFITGGAPMPEALIKIYAAK-------NIEVVQGYALTESCGGGTLLLSED-------ALRKAGSAGRATMFTDVAVRGDDGVIRGEVVIKSDILLKEYWNRPEATRDAFDNGWFRTGDIGEIDEGYLYIKDRLKDMIISGGENVYPAEIESVIIGVPGVSEVAVIGLPDEEIAAAIVVADQNEVSEQQIVEYCGTRLAR-----PKKVIFA--EAIPRNPTGKILKTVLREQYSATV............................ 509
40 -65.9001t5d_X mol:protein length:504 4-chlorobenzoyl CoA ligase  ali model follow..  19  3....TVNEMLRRAATRAPDHCALAVP-ARGLRLTHAELRARVEAVAARLHADGLRPQQRVAVVAPNSADVVIAILALHRLGAVPALLNPRLKS-------AELAELIKRGEMTAAVIAVGRQVADAIFQSGSGARIIFLGDLVR------DGEPYSYGPPIEDPQREPAQPAFIFYTSGTTGLPKAAIIPQRAAESRVLFMSTQVGLGRHNVVLGLMPLYHVVGFFAVLVAALALDGTYVVVEE-----RPVDALQLVQQEQVTSLFATPTHLDALAAAAAHAGSS---LKLDSLRHVTFAGATMPDAVLETVHQHLP------GEKVNIYGTTEAMNSLYMRQPKTG------------TEMAPGFFSEVRIVRVANGEEGELIVAASDAFVGYLNQPQATAEKLQDGWYRTSDVAVWPEGTVRILGRVDDMIISGGENIHPSEIERVLGTAPGVTE--VVVIGLADQTACVVPRLGETLSADALDTFCRSSELADFKRPKRYFIL---DQLPKNALNKVLRRQLVQQVSS.............................. 504
41 -65.9003etc_A mol:protein length:580 AMP-binding protein  ali model follow..  13  50.......DVVDVYARDSPEKLAMIWCDDNEKIFTFKDLKYYSDKAANFFVKHGIGKGDYVMLTLKSRYDFWYCMLGLHKLGAIAVPATHMLKTRDIVYRIEGLKMIVCIAEDDVPEQVDEAHAECGDIPLKKAKVGGDVLEGWIDFRKELEESSPIFERPTGEVSTKNEDICLVYFSSGTAGFPKMVEHDNTYPLGHILTAKYWQNVEDDGLHYTVADSGWGKCVWGKLYGQWIAGCAVFVYDYDRF--EAKNMLEKASKYGVTTFCAPPTIYRFLIK------EDLSHYNFSTLKYAVVAGEPLNPEVFNRFLEFTG-------KLMEGFGQTETVVTIATFPWME---------PKPGSIGKPTPGYKIELMDCEVGEEGEIVINTVGLFVHYGKDPERTEETWHDGYYHTGDMAWMEDGYLWFVGRADDIIKTSGYKVGPFEVESALIQHPAVLECAITGVPDPQVIKATIVLTKDYTPSDSLKNELQDHVKNVTAPYKYPRIIEFVPELPKTISGKIRRVEIRDKDQS.............................. 569
42 -65.8003a9u_A mol:protein length:536 4-coumarate--CoA ligase  ali model follow..  19  23....PLHSYVLENLSNHSSKPCLINGAN-GDVYTYADVELTARRVASGLNKIGIQQGDVIMLFLPSSPEFVLAFLGASHRGAIITAANPFSTPA-------ELAKHAKASRAKLLITQACYYEKVKDFARESDVKVMCVDSAPD-GCLHFSELTQADENEAPQVDISPDDVVALPYSSGTTGLPKGVMLTHKGLITSVAQQVDNLYFHSEDVILCVLPMFHIYALNSIMLCGLRVGAPILIMPK-----EIGSLLGLIEKYKVSAPVVPPVMMSIA------KSPDLDKHDLSSLRMIKSGGAPLGKELEDTVRAKFPQA-----RLGQGYGMTEAGPVLAMCLAFA----KEPFDIKPGACGTVVRNAEMKIVDLPRNQPGEICIRGDQIMKGYLNDPEATSRTIKEGWLHTGDIGYIDDDELFIVDRLKELIKYKGFQVAPAELEALLIAHPEISDAAVVGLKDEDAVAFVVKSEKSQATEDEIKQYISKQVIFYKRIKRVFFI----EAIPKAPSGKILRKNLKEKLAG.............................. 535
43 -65.8001md9_A mol:protein length:539 2,3-dihydroxybenzoate-AMP ligase  ali model follow..  18  22WAGETFGDLLRDRAAKYGDRIAIT---CGNTHWSYRELDTRADRLAAGFQKLGIQQKDRVVVQLPNIKEFFEVIFALFRLGALPVFALPSHRSS-------EITYFCEFAEAAAYIIPDAYSRSLARQVQSKLPTLKNIIVAGEAE--EFLPLEDLHTEPVKLPEVKSSDVAFLQLSGGSTGLSKLIPRTHDDYIYSLKRSVEVCWLDHSTVYLAALPMAHNYPLSPGVLGVLYAGGRVVLSPS-----SPDDAFPLIEREKVTITALVPPLAMVWMDA-----ASSRRDDLSSLQVLQVGGAKFSAEAARRVKAVFG-------TLQQVFGMAEGLVNYT--------RLDDPEEIIVNTQGKPMPYDESRVWDVKPGETGHLLTRGPYTIRGYYKAEEHNAASFEDGFYRTGDIVRLRDGYIVVEGRAKDQINRGGEKVAAEEVENHLLAHPAVHDAAMVSMPDQERSCVFIIPRDEAPKAAELKAFLRERGLAAYKIPDRVEFV---ESFPQTGVGKVSKKALREAISEK............................. 532
44 -65.2003qya_A mol:protein length:582 Luciferase  ali model follow..  15  45LEDGTAGEQLHKAMKRQVPGTIAFTDAHAEVNITYSEYFEMACRLAETMKRYGLGLQHHIAVCSENSLQFFMPVCGALFIGVGVAPTNDIYNER-------ELYNSLSISQPTIVFCSKRALQKILGVQKKLPIIQKIVILDSREDIESHLPAGFNEYDYIPDSFDRETATALIMNSSGSTGLPKGVELTHKNICVRFSHCRDPVQIIPDTAILTVIPFHHGFGMF-TTLGYLTCGFRIVLMYR-----EEELFLRSLQDYKIQALLVPTLFSFFA------KSTLVDKYDLSNLHEIASGGAPLAKEVGEAVAKRFKLP-----GIRQGYGLTETTSAIIITPRGRDDKP---------ACGKVVPFFSAKIVDLGVNQRGELCVKGPMIMKGYVNNPEATSALIKDGWLHSGDIAYYKDGYFFIVDRLKSLIKYKGYQVPPAELESILLQHPFIFDAGVAGIPDPDAAAVVVLEEGKTMTEQEVMDYVAGQVTASKRLRGGVKFV---DEVPKGLTGKIDARKIREILMMGKKSKL........................ 576
45 -64.8004dg8_A mol:protein length:620 PA1221  ali model follow..  16  25.AHPTVVARFSEMAALHPHREAIRD---RFGSVDYRQLLDSAEQLSDYLLEHYPQPGVCLGVYGEYSRESITCLLAILLSGHHYLYIDLKQPA-------AWNAELCRQVDCRLILDCSTTPTPANGLPCVPVRHLP------------------AAPASVARPCFAADQIAYINFSSGTTGRPKAIACTHAGIT-RLCLGQSFLAFAPQMRFLVNSPLSFDAATL-EIWGALLNGGCCVLNDLG--PLDPGVLRQLIGERGADSAWLTASLFNTLVDLDPDC--------LGGLRQLLTGGDILSVPHVRRALLRHPRL-----HLVNGYGPTENTTFTCCHVVTDD-----DLEEDDIPIGKAIAGTAVLLLDAEPDRAGEIVAFGAGLAQGYRNDAARTRASFLLRAYRTGDRAYDEQGRLRFIGRGDGQVKLNGYRLDLPALEQRFRRQPGILDCALLV-NGVKQLLCAWTGKA---------DASPQALLRQLPTWQRPHACVRVEALPLTAHGKLDRAALLR.................................. 509
46 -64.3006h1b_D mol:protein length:499 Fatty acid CoA ligase  ali model follow..  17  1...QGPAMGYARRVMDGIGEVAVTG---AGGSVTGARLRHQVRLLAHALTEAGIPPGRGVACLHANTWRAIALRLAVQAIGCHYVGLRPTAAV-------TEQARAIAAADSAALVFEPSVEARAADLLERV--SVPVVLSLGPTSRGRDILAASVPEGTPLRYREHPEGIAVVAFTSGTTGTPKGVAHSSTAMSACVDAAVS-MYGRGPWRFLIPIPLSDLGGEL--AQCTLATGGTVVLLEEF----QPDAVLEAIERERATHVFLAPNWLYQLAEH-----PALPRSDLSSLRRVVYGGAPAVPSRVAAARERMGA------VLMQNYGTQEAAFIAALTPDDH------ARRELLTAVGRPLPHVEVEIRDLPRGAVGEVWVRSPMTMSGYWRDPERTAQVLSGGWLRTGDVGTFEDGHLHLTDRLQDIIIVEAYNVYSRRVEHVLTEHPDVRA--AAVVGVPDPCAAVVVADGADPDPEHLRALVRDHLGDLH--VPRRVEFVR--SIPVTPAGAPDKVKVRTWFTD.............................. 499
47 -64.2005buq_A mol:protein length:494 2-succinylbenzoate--CoA ligase  ali model follow..  16  6....EQPNWLMQRAQLTPERIALIY---EDQTVTFAELFAASKRMAEQLAAHSVRKGDTAAILLQNRAEMVYAVHACFLLGVKAVLL-------NTKLSTHERLFQLEDSGSGFLLTDSSFEKKEYEHIVQTIDVDELMKE--------------AAEEIEIEAYMQMDATATLMYTSGTTGKPKGVQQTFGNHYFSAVSSALNLGITEQDRWLIALPLFHISGL-SALFKSVIYGMTVVLHQR-----SVSDVLHSINRHEVTMISAVQTMLASLLEE--------TNRCPESIRCILLGGGPAPLPLLEECREKGFP-------VFQSYGMTETCSQIVTLSPEF-------SMEKLGSAGKPLFSCEIKIERCEPYEHGEIMVKGPNVMKSYFNRESANEASFQNGWLKTGDLGYLNEGFLYVLDRRSDLIISGGENIYPAEVESVLLSHPAVAEAGVSGAEDKKKVPHAYLVLHKPVSAGELTDYCKERLAK-----PAKFFVL--DRLPRNASNKLLRNQLKDARKGELL........................... 488
48 -63.9005u2a_A mol:protein length:564 AMP-dependent synthetase and ligase  ali model follow..  17  40...NACIECCDRYTGENRVALRAISIDNTLTELTFEDLRDMSARVGNMLADAGISAGDVVAGLLPRTPELVATILGAWRIGAIYQPLFTAFGPKA-------IEQRFGTSGAKLVVTNLANRSKLAEVENPRVATILAPGESLPEGDIDFRAAVAAASTECEPVMRKGSDLFMMMSTSGTAGLPKGVPVPLRALMAFGAYMRDAVGLRSDDIFWNIADPGWAYGLYYAVTGPLLLGVPTILNEGG----TAENTYDIIERLGVTSLAGSPTAFRLLIAA----GPESAARVKGRLRVVSSAGEPLNPEVIRWFDACLG-------PIHDHYGQTELGMVVNNHHGLEHPVRQG-------SAGYAMPGYRVAVLDVGPNEPGVLAIDIDNSPLWFTGYYKKDTPSISGGYYRTGDTVEFPDGSISFIGRADDVITSSGYRIGPFDVESALLKHPAVNEAAVVGVPDPEIVKAFVILAPGFEGTPELAEELALHVKKQLSAHAYPRQIDFVAELPKTPSGKIQRFLLRKAEVEKQ............................ 554
49 -63.9003nyq_A mol:protein length:505 Malonyl-CoA Ligase  ali model follow..  20  16..SSLFPALSPAPTGAPADRPALRF---GERSLTYAELAAAAGATAG-----RIGGAGRVAVWATPAMETGVAVVAALLAGVAAVPLNPKSGD-------KELAHILSDSAPSLVLAPPDAELPPALGA------------------LERVDVDVRARGAVPEDGADDGDPALVVYTSGTTGPPKGAVIPRRALATTLDALADAWQWTGEDVLVQGLPLFHVHGLVLGILGPLRRGGSVRHLGR-----STEGAARELNDGATMLFGVPTM-YHRIAETLPADPE--LAKALAGARLLVSGSAALPVHDHERIAAATG------RRVIERYGMTETLMNTSVRADGE---------PRAGTVGVPLPGVELRLVELDGESVGEIQVRGPNLFTEYLNRPDATAAAFEDGFFRTGDMAVRPDGYVRIVGRATDLIKSGGYKIGAGEIENALLEHPEVREAAVTGEPDPDVAWIVPADPAAPPALGTLADHVAARLAP-----PRVVRYL--DAVPRNDMGKIMKRALNRD................................. 499
50 -63.7005dv9_A mol:protein length:573 Luciferin 4-monooxygenase  ali model follow..  15  34LEDGTAGEQLHKAMKRLVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNER-------ELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDVTSHLPPGFNEYDFVPESFDRDKTIALIMNSSGSTGLPKGVALPHRTACVRFSHARDPIQIIPDTAILSVVPFHHGFGMF--TLGYLICGFRVVLMYR-----EEELFLRSLQDYKIQALLVPTLFSFFA------KSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLP-----GIRQGYGLTETTSAILITPEGD---------DKPGAVGKVVPFFEAKVVDLGVNQRGELCVRGPMIMSGYVNNPEATNALIKDGWLHSGDIAYWEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFV---DEVPKGLTGKLDARKIREILIKAKKGGKSK...................... 566
51 -63.6006abh_A mol:protein length:546 Red-bioluminescence eliciting luciferase  ali model follow..  14  16VFPGTAGLQLYQSLYKYSYITDGIIDAHTNEVISYAQIFETSCRLAVSLEKYGLDHNNVVAICSENNIHFFGPLIAALYQGIPMATSNDMYTER-------EMIGHLNISKPCLMFCSKKSLPFILKVQKHLDFLKKVIVIDSMYDVSRYTDHAFDPVKFNPKEFDPLERTALIMTSSGTTGLPKGVVISHRSITIRFVHSSDGTRIAPDTSILAIAPFHHAFGLF--ALAYFPVGLKIVMVKK-----EGEFFLKTIQNYKIAIVVPPPIMVYLA------KSPLVDEYNLSSLTEIACGGSPLGRDIADKVAKRLKVH-----GILQGYGLTETCSALILSPNDRELKK---------AIGTPMPYVQVKVIDLGPREKGEICFKSQMLMKGYHNNPQATRDALKDGWLHTGDLGYYEDRFIYVVDRLKELIKYKGYQVAPAELENLLLQHPNISDAGVIGIPDEFASACVVLEPGKTMTEKEVQDYIAELVTTTKHLRGGVVFI---DSIPKGPTGKLMRNELRAIFAREQ............................ 541
52 -63.6003ite_A mol:protein length:562 SidN siderophore synthetase  ali model follow..  17  18.STVPPSHYIETWAKTHPEWKAVEVATGVTEDWTYKKLNETANQVANLIIHASLH-GRAIAVSLDRSLIAFAIIVGIMKSGNTYVPIEAGLPN-------DRKSFLLRDSRAAMAFVCDNNFDGVELPPETKVLDTKNQSFIENLS---------TQDTSDILNNYPENLDAYLLYTSGSTGTPKGVRVSRHNLSSFSDAWGKSLELGGVGKFLCLASRAFDVH-IGEMFLAWRFGLCAVTGERLSMLDD---LPRTFRELGVTHAGIVPSLLDQTGLVPE---------DAPHLVYLGVGGEKMTPRTQQIWSSS------DRVALVNVYGPTEVTIGCSAGRILP--------DSDTRCIGHPLGDSVAHVLAVKKGMAGELVIEGSLVANGYLNRPDAKGDINGRKMYRTGDIVMDADSSILFLGRKDEQVKVRGQRLELGEVSEVIRSLSPTDIDVVVSFVASSGAAVRGELRWINENYKEINNSLRQACEQTLPAYMVPDFIIPISFIPRDTSAKTDAKALEHMFHTLSLGELFGESSSLVNKP............. 560
53 -63.3003ivr_A mol:protein length:509 Putative long-chain-fatty-acid CoA ligase  ali model follow..  18  3LHDFTLADVYRRNAALFPDRTAFMV---DGVRLTHRDYLARAERLASGLLRDGVHTGDRVAILSQNCSEMIELIGAVALIGAILLPV-------NYRLNADEIAFVLGDGAPSVVVAGTDYRDIVAGVLP-SLGGVKKAYAIGDGSGPFAPFKDLASDTPFSAPEFGAADGFVIIHTAAVGGRPRGALISQGNLLIAQSSLVDAWRLTEADVNLGMLPLFHVTGL-GLMLTLQQAGGASVIAAK-----DPAQAARDIEAHKVTVMAEFAPMLGNIL-------DQAAPAQLASLRAVTGLDTPETIERFEAT--------CPNATFWATFGQSETSGLSTFAPYRD----------RPKSAGRPLFWRTVAVVDLPPGEVGEIVLRGPTVFKGYWNNAAATQHAFRNGWHHTGDMGRFADGYLFYAGRAKELIKTGGENVYPAEVEGALKQHPAIAD--AVVIGVPDPKAVCVCKPGESIAADALAEFVASLIAR----KPKHVVFV--EALPKDAKGAIDRAAVKTAH................................ 499
54 -63.3002vsq_A mol:protein length:1304 SURFACTIN SYNTHETASE SUBUNIT 3  ali model follow..  17  462.ETKPLTYWFKEAVNANPDAPALTY---SGQTLSYRELDEEANRIARRLQKHGAGKGSVVALYTKRSLELVIGILGVLKAGAAYLPVDPKLPE-------DRISYMLADSAAACLLTHQEMKEQAAEL------------PYTGTTLFIDDQTRFEEQASDPATAIDPNDPAYIMYTSGTTGKPKGNITTHANIQ-GLVKHVDYMAFSDQDTFLSVSNYAFDAF-TFDFYASMLNAARLIIADEHT-LLDTERLTDLILQENVNVMFATTALFNLLTDAGEDW--------MKGLRCILFGGERASVPHVRKALRIMGPG-----KLINCYGPTEGTVFATAHVVHDLP-----DSISSLPIGKPISNASVYILNQPFGAVGELCISGMGVSKGYVNRADLTKEKFGETLYRTGDLAWLPDGTIEYAGRIDDQVKIRGHRIELEEIEKQLQEYPGVKDAVVVA-ESGDASINAYLVNRTQLSAEDVKAHLKKQLPA-YMVPQTFTFL---DELPLTTNGKVNKRLLPK.................................. 956
55 -63.3003ipl_A mol:protein length:501 2-succinylbenzoate--CoA ligase  ali model follow..  16  2....SLDFWLYKQAQQNGHHIAITD---GQESYTYQNLYCEASLLAKRL---KAYQQSRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTP-------NEMTNQMRSIDVQLIFCTLPLELRGFQIVSLTTNGLLDNTMGIQYDTSNETVVPKESPSNILNTSFNLDDIASIMFTSGTTGPQKAVPQTFRNHYASAIGCKESLGFDRDTNWLSVLPIYHISGL-SVLLRAVIEGFTVRIVDK-----NAEQILTMIKNERITHISLVPQTLNWLMQQ--------GLHEPYNLQKILLGGAKLSATMIETALQYNLP-------IYNSFGMTETCSQFLTATPEML-------HARPDTVGMPSANVDVKIKNPNKEGHGELMIKGANVMNGYL-YPTDLTGTFENGYFNTGDIAEIHEGYVMIYDRRKDLIISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTQVPKLYFVSESDISKAQLIAYLSKHLAK-----PKHFEKVD--TLPYTSTGKLQRNKLYRE................................. 494
56 -63.2002d1q_A mol:protein length:548 Luciferin 4-monooxygenase  ali model follow..  16  20IEEGSAGTQLRKYMERYAKLGAIAFTNVTGVDYSYAEYLEKSCCLGKALQNYGLVVDGRIALCSENCEEFFIPVIAGLFIGVGVAPTNEIYTLR-------ELVHSLGISKPTIVFSSKKGLDKVITVQKTVTTIKTIVILDSKVDIKRNTPPGFQASSFKTVEVDRKEQVALIMNSSGSTGLPKGVQLTHENIVTRFSHARDPIQVSPGTAVLTVVPFHHGFGMF-TTLGYLICGFRVVMLTK-----DEETFLKTLQDYKCTVILVPTLFAILN------KSELLNKYDLSNLVEIASGGAPLSKEVGEAVARRFNLP-----GVRQGYGLTETTSAIIITPEGD---------DKPGASGKVVPLFKAKVIDLGPNRRGEVCVKGPMLMKGYVNNPEATKELIEEGWLHTGDIGYYEEKHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPSIFDAGVAGVPDPVAGAVVVLESGKNMTEKEVMDYVASQVSNAKRLRGGVRFV---DEVPKGLTGKIDGRAIREILKKPV............................ 545
57 -63.2006aaa_A mol:protein length:547 Blue-shifted Luciferase  ali model follow..  16  18LDIGTAGEQLHKFMKKYATGTIAFTDAHNGVNVTYAEYFEMACRLAQSMKNYGLTLKHRIAVCSENSLQFFMPICGALFIGVGVAPTNDIYNER-------ELYNSLGISQPTIVFCSKRALQKILGVQQKLPIIEKIIILDSQNSFIRQFLPETFNEYDYVPDSFALNTTAFIMNSSGSTGLPKGVDLTHQNIVVRFSHCRDPIQIIPDTSILSVIPFHHGFGMS--TLGYLVCGFRIVLMYR-----EEELFLRSLQNYKCQALLVPTLFSFFA------KSTLVDKYDLSNLHEVASGGAPLAKEVGEAVAKRFNLV-----GIRQGYGLTETTSACIITPEGD---------NKPGACGKVVPFFSAKVTDLGPNQRGELWLKGPMVMKGYVNNPEATHSLIKEGWVRTGDIAYYEDEHFFIVDRLKSLIKYKGYQVPPAELESILLQHPYIFDAGVAGIPDPDAAAVVVLEEGKTMTEKEVMDYVAGQVTSSKRLRGGVKFV---DEVPKGLTGKIDGRKIREILLKAKKSKL........................ 547
58 -63.0004g37_A mol:protein length:555 Luciferin 4-monooxygenase  ali model follow..  15  22LEDGTAGEQLHKAMKRLVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVSSENSLQFFMPVLGALFIGVAVAPANDCYNER-------ELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDVTSHLPPGFNEYDFVPESFDRDKTIALIMNSSGSTGLPKGVALPHRALAVRFSHARDPIQIAPDTAILSVVPFHHGFGMF-TTLGYLISGFRVVLMYR-----EEELFLRSLQDYKIQALLVPTLFSFLA------KSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLP-----GIRQGYGLTETTSAILITPKGD---------DKPGAVGKVVPFFEAKVVDLGVNQRGELSVRGPMIMSGYVNNPEATNALIKDGWLHSGDIAYWEDEHFFIVDRLKSLIKYKGCQVAPAELESILLQHPNIFDAGVAGLPDDDAAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFV---DEVPKGLTGKLDARKIREILIKAKKGGKSK...................... 554
59 -62.2004lgc_A mol:protein length:539 Bile acid-coenzyme A ligase  ali model follow..  12  44....TPGKQLEYVSECKPDSTAVICLDKECSVITWHQLHVYSSQLAWYLIENEIGPGSIVLTMFPNSIEHIIAVFAIWKAGACYMPM-------SYKAAESEIREACDTIHPNAAFAECKIPGLKFCLSAD-------------------EIYEAMEGRSKEMPSDRLANPNMISLSGGTSGKMKFIRQNLPCGLDDIRSWSLMSGMGFEQRQLLVGPLFHGAPH-SAAFNGLFMGNTLVLTRN-----CPGNILNMIKKYKIEFIQMVPTLMNRLAKL-----EGVGKEDFASLKALCHTGGVCSPWLKQIWIDLLGP-----EKIYEMYSMTECIGLTCIRGDE---------VKHPGSIGRPVGDSKVSIRDVAPFEIGEIYMTAPASYLVTEYINWEPLEVKEGGFRSVGDIGYVEQGYLYFSDRRSDMLVSGGENVFATEVETALLRYKDILDAVVVGIPDEDRRLHAVIETGKEIPAEELKTFLRKYLTP-----PKTFEFVR--SIRRGDNGKADRKRILEDCIARG............................ 532
60 -61.9005mso_A mol:protein length:1174 Carboxylic acid reductase  ali model follow..  17  62...AQRSVEFVTDAGTGHTTLRLL---PHFETISYGELWDRISALADVLSTQTVKPGDRVCLLGFNSVDYATIDMTLARLGAVAVPLQTSAAI-------TQLQPIVAETQPTMIAASVDALADATELALSGQTATRVLVETLAEAIARGDVPRGASAGSAPGTDVSDDSLALLIYTSGSTGAPKGAMYPRRNVATFWRKRTWFEGGYEPSITLNFMPMSHVMGRQ-ILYGTLCNGGTAYFVAK----SDLSTLFEDLALVRPTELTFVPRVWDMVFDEFQSEVDRRNDVLGGRYTSALTGSAPISDEMKAWVEELLD------MHLVEGYGSTEAGMILIDGAIRRP------AVLDYKLVDVPDLGYFLT----RPHPRGELLVKTDSLFPGYYQRAEVTADVFADGFYRTGDIMEVGPEQFVYLDRRNNVLKLQGEFVTVSKLEAVFGDSPLVRQIYIYGNSARAYLLAVIVEELKARLGDSLQEVAKAAGLQSYEIPRDFIIETTPWTLLLTGIRKLARPQLKKHYGELLEQIYTDLAHGQADELRSLRQSGADAPVL 654
61 -60.7001ult_A mol:protein length:541 long chain fatty acid-CoA ligase  ali model follow..  17  19....NLWDFLERAAALFGRKEVVSRLHTEVHRTTYAEVYQRARRLMGGLRALGVGVGDRVATLGFNHFRHLEAYFAVPGMGAVLHTA-------NPRLSPKEIAYILNHAEDKVLLFDPNLLPLVEAIRG-ELKTVQHFVVMDEKAPEGYLAYEEALGEEADPVRVPERAACGMAYTTGTTGLPKGVVYSHRALVLHSASLVDGTALSEKDVVLPVVPMFHVNAW-CLPYAATLVGAKQVLPGPR----DPASLVELFDGEGVTFTAGVPTVWLALADY-----LESTGHRLKTLRRLVVGGSAAPRSLIARFERM---------EVRQGYGLTETSPVVVQNFVKSHLESLSEEEKLKAKTGLPIPLVRLRVADKDGKALGEVQLKGPWITGGYYGNEEATRSALPDGFFRTGDIAVWEEGYVEIKDRLKDLIKSGGEWISSVDLENALMGHPKVKEAAVVAIP-ERPLAVVVPRGEKPTPEELNEHLLKAGFAK-----PDAYVFA--EEIPRTSAGKFLKRALREQYKNYY............................ 538
62 -60.3004zxh_A mol:protein length:1320 ABBFA_003403  ali model follow..  17  478YAQHDLFAMILKQIDERGDNHALTS---NDHTVSYRELGQHIAGIAEYLRAHGITQGDRVGLMLDRTALLPAAILGIWAAGAAYVPLDPNFPT-------ERLQNIIEDAEPKVILTQTELMDGLNVSVPRL-----------------DINQAGVVALEQVRETLAFGDIAYVMYTSGSTGKPKGVRIGHPSIINFLLSMNDRLQVTTETQLLAITTYAFDISIL-ELLIPLMYGGVVHVCPR-EVSQDGIQLVDYLNAKSINVLQATPATWKMLLD---------SEWSGNAGLTALCGGEALDTILAEKLLGKVG-------CLWNVYGPTETTVWSSAAR---------ITDAKYIDLGEPLANTQLYVLDVPPGVMGELWIGGDGLAVDYWQRPELTDAQFAGRLYRTGDKVLRTDGRLTHHGRLDFQVKIRGFRIELGEIENVLKQIDGITDAVVLV-DNDQKLVAYV------TGQELDIAGLKKNLQIHLPAYMVPSAFIRLDEFPMTANKKLDRKAFPE.................................. 962
63 -59.3005c5h_A mol:protein length:453 2-succinylbenzoate--CoA ligase  ali model follow..  18  9........PWRHWRQVRGETIALRL---NDEQLNWRELCARVDELASGFAVQGVVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQ-------PLLEELLPNLTLQFALVPDGEN-----------------------TFPALTSLHIQLVEGAHAATWQPTRLCSMTLTSGSTGLPKAAVHTYQAHLASAQGVLSLIPFGDHDDWLLSLPLFHVSGQ-GIMWKWLYAGARMTVRDKQ----PLEQMLAGCT----HASLVPTQLWRL-----------LVNRSSVSLKAVLLGGAAIPVELTEQAREQGIR-------CFCGYGLTEFASTVCAKEAD-----------GLADVGSPLPGREVKIVN------NEVWLRAASMAEGYWRNGQLVSLVNDEGWYATRDRGEMHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGHRPVAVMEYDHESVDLSEWVKDKLAR----QPVRWLTLP--PELKNGGIKISRQALKEWVQRQQ............................ 453
64 -58.6005msc_A mol:protein length:1174 Carboxylic acid reductase  ali model follow..  16  57.DRPAAGQRAFELNTDDATGRTSLRLLPRFETITYRELWQRVGEVAAAWHENPLRAGDFVALLGFTSIDYATLDLADIHLGAVTVPLQASAAV-------SQLIAILTETSPRLLASTPEHLDAAVECLLAGTTPERLVVFDYHPEDDDQRAARDLPAAPLFVPDTDDDPLALLIYTSGSTGTPKGAMYTNRLAATMWQGNSMLQGSQRVGINLNYMPMSHIAGRI-SLFGVLARGGTAYFAAK----SDMSTLFEDIGLVRPTEIFFVPRVCDMVFQRYQSELDRRSVAGAGRFLVAVVGSAPLAAEMKTFMESVLD-------PLHDGYGSTEAGASVLLDNQIQRP----------PVLDYKLVDVPELGYFRRPHPRGELLLKAETTIPGYYKRPEVTAEIFEDGFYKTGDIVELEHDRLVYVDRRNNVLKLQGEFVTVAHLEAVFASSPLIRQIFIYGSSERSYLLAVIGRDTATLKSALAESIQRIAKDANLQPYEIPRDFLIETEPFTIANGLLSGIAKLKERYGAQLEQMYTDLATGQADELLALRREAADLP. 656
65 -58.4005msp_A mol:protein length:1188 Thioester reductase domain-containing protein  ali model follow..  16  68...PALAQRAFEITKDPITGRAVATLLPKFETVSYRELLERSHAIASELANHAEKAGEFIATIGFTSTDYTSLDIAGVLLGLTSVPLQTGATT-------DTLKAIAEETAPAVFGASVEHLDNAVTTALARLAEAGSAVLVDTLDEVIARGRALPRVALPPATDAGDDSLSLLIYTSGSTGTPKGAMYPERNVAQFWGGIWHNSAPDVPDIMVNFMPLSHVAGRI-GLMGTLSSGGTTYFIAK----SDLSTFFEDYSLARPTKLFFVPRICEMIYQHYQSELDRIGAAD-GRVLTAGSGSAPMSPELTAFIESVLQ-------HLVDGYGSTEAGPVWRDR----------------KLVKPPVTEHKLIDVPDSPYPRGELAIKTQTILPGYYKRPETTAEVFEDGFYLTGDVVEVAPEEFVYVDRRKNVLKLQGEFVALSKLEAAYGTSPLVRQISVYGSSQRSYLLAVVVPTPEALAKYGDGEAVKSALGDSLGLQSYEVDFIIETDPFTIENGILSRPKVKARYGERLEALYAQLAETQAGELRSIRVGAGERPVI 671
66 -58.4003tsy_A mol:protein length:979 Fusion Protein 4-coumarate--CoA ligase 1, Resveratrol synthase  ali model follow..  18  56....SLHDYIFQNISEFATKPCLINGPT-GHVYTYSDVHVISRQIAANFHKLGVNQNDVVMLLLPNCPEFVLSFLAASFRGATATAANPFFTPA-------EIAKQAKASNTKLIITEARYVDKIKPLQNDDGVVIVCIDDNESLRFTELTQSTTEASEVIDSVEISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPK-----EINLLLELIQRCKVTAPMVPPIVLAIA------KSSETEKYDLSSIRVVKSGAAPLGKELEDAVNAKFPNA-----KLGQGYGMTEAGPVLAMSLGFA----KEPFPVKSGACGTVVRNAEMKIVDLSRNQPGEICIRGHQIMKGYLNNPAATAETIKDGWLHTGDIGLIDDDELFIVDRLKELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKEEAAVAFVVKSKDSELSEDDVKQFVSKQVVFYKRINKVFFT----ESIPKAPSGKILRKDLRAKLANGLGSGMASVEEFRNAQRAKGPATILAIGT. 605
67 -55.6005ja1_A mol:protein length:1295 Enterobactin synthase component F  ali model follow..  18  454IPETTLSALVAEQAAKTPDAPALAD---ARYLFSYREMREQVVALANLLRERGVKPGDSVAVALPRSVFLTLALHAIVEAGAAWLPLDTGYPD-------DRLKMMLEDARPSLLITTDDQLPRFSDVPNLTS---------------LCYNAPLTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRLLWMQNHYPLTGEDVVAQKTPCSFDVS-VWEFFWPFIAGAKLVMAEPEA-HRDPLAMQQFFAEYGVTTTHFVPSMLAAFVASLTPQTARQS---CATLKQVFCSGEALPADLCREWQQL------TGAPLHNLYGPTEAAVDVSWYPAFGEELAQVRGSS--VPIGYPVWNTGLRILDVPPGVAGDLYLTGIQLAQGYLGRPDLTASRFGERMYRTGDVAWLDNGAVEYLGRSDDQLKIRGQRIELGEIDRVMQALPDVEQAVTHACVIARQLVGYLVSQSGLPLDTSALQAQLRETLPPHMVPVVLLQL---PQLPLSANGKLDRKAL------------LPELKAQAPGRAPKAGSETIIAA. 984
68 -55.4005u89_A mol:protein length:1080 Amino acid adenylation domain protein  ali model follow..  16  21HPEENFLQLFEKQAERIPEAIAVIC---EDQALSYTELNQQANRLAHFLMEYGVGPEQYVALALPRSAEMVIAMLAVLKTGAAYLPLDLDYP-------DERIAFMLEDTKPVCIVTSSSVQSKLSHFPSCSTIILDH----------ETEQAIKHYPDTNVPKTQSPLHPAYVIYTSGSTGKPKGVVVPFHSLNNFLLAMREKFALKEHDRLLAVTTIAFDIS-ALEIFLPLISGASLVVAKKET-IQDPQALAAVISDKEITIMQATPTLWHMLVT---------HHPDCIAGLRVLVGGEALSSGLASALHRL-------ACEVTNLYGPTETTIWSTMSPLHP-------DDARAPSIGRPIWNTQVYVLDVPPGVVGELYIAGSGLARGYLRRPDLTAERFGSRMYRTGDLVWRMDGSLDYIGRVDHQIKLRGFRIEIGEIEAVLSQCDLVERALVVA-QPGDQRLVAYVIPCEQSKGTLDLAELRRYVSERLPDYMVPSAFMVLNEFPLTPNGKIDRKAL.................................... 518
69 -54.5005n81_A mol:protein length:427 Tyrocidine synthase 1  ali model follow..  18  31...KSIHQLFEEQAEAFPDRVAIVF---ENRRLSYQELNRKANQLARALLEKGVQTDSIVGVMMEKSIENVIAILAVLKAGGAYVPIDIEYPR-------DRIQYILQDSQTKIVLTQKSVSQLVHDV------------GYSGEVVVLDEEQLDARETANLHQPSKPTDLAYVIYTSGTTGKPKGTMLEHKGIANLQSFFQNSFGVTEQDRIGLFASMSFDVS-VSEMFMALLSGASLYILSKQT-IHDFAAFEHYLSENELTIITLPPTYLTHLTPE-----------RITSLRIMITAGSASSAPLVNKWKDKLR--------YINAYGPTECLVATIWEAPSNQ------LSVQSVPIGKPIQNTHIYIVNLPTGSEGELCIGGVGLARGYWNRPDLTAEKFGEKMYRTGDLAWLTDGTIEFLGRI.................................................................................................................................... 421
70 -53.6005oe3_A mol:protein length:407 Anthranilate--CoA ligase  ali model follow..  20  1MSTLANLTEVLFRLDFDPDTAVYHY---RGQTLSRLQCRTYILSQASQL-ARLLKPGDRVVLALNDSPSLACLFLACIAVGAIPAVINPKSRE-------QALADIAADCQASLVVREADAPSLSGPLAPLTLRAAAGRPLLDDFSLDAL--VGPADLDWSAFHRQDPAAACFLQYTSGSTGAPKGVMHSLRNTLGFCRAFATELALQAGDRLYSIPKMFFGYGMGNSLFFPWFSGASALLDDT---WPSPERVLENLVAFRPRVLFGVPAIYASLRPQ--------ARELLSSVRLAFSAGSPLPRGEFEFWAAH---------EICDGIGATEVGHVFLANRPGQ---------ARADSTGLPLPGYECRLVDEEAGRQGVLLVRGPGLSPGYWRASEEQQARFAGGWYRTGDLFERESGAYRHCGRED................................................................................................................................... 399
71 -53.2004w8o_A mol:protein length:427 luciferase-like enzymeAMP-CoA-ligase  ali model follow..  14  15FDKISFGEFLFECCEKYADRICQIDG-DLDKSETYSSVKTRSTRVALNLQKKGITSTDVVCFCSTNSLDNSIPLIASSYLGAKVVNLDPTLSV-------RNIQHLLSLVTPRIIFVEEESLKLIEKSLKGASCEIIVFGKSTKHGTFAEMTLPCGDEKAFKPSKTDIDDTAVMFFSSGTTGLPKAICHSHRSFLQIVETSF--YCGYDCRSILHFTTMYWITGMA--LGRTFLDGSTRVFARS-----EGEKTLQMIEKYKLTLFVAPIYTYQLT------NVPNPERYDLSSFRCLLTGGTPMSTDQYKKLTQLFPKA-----QVLFGYGMSEIGLLSIFHPEDD----KHLIDTKVGSCGKVSPRTLLKIVNVGPNQKGELRVKSDAMMTGYYRNDSAEC-FDGDGFLKTGDIGYYDDGCVYVIERIKEMF................................................................................................................................ 427
72 -50.4005gxd_A mol:protein length:630 AMP-dependent synthetase and ligase  ali model follow..  15  53TCFNAVDRHVQAGNGDRVAIIHDSPVTHTKQEITYAELQERVSLLAGALRAKGIEKGDRVLIYMPMVPQALEAMLACARLGAIHSVVFGGFAANE-------LAVRIDDATPKAIIAASCGIEPGRVVHYKPLLDGAIDLATHKPDFCLIFQREQYGVDPAECVPVAGNHPAYILYTSGTTGQPKGVLRPTAGLVALNWTMKNIYNVDPGDVFVGWV-----VGHSYICYAPLIHGNTTIVFEGKPVGTDAGTFWRVISEHKVKSFFTAPTALRA-VKREDPNGEFIGKYDLSHLKTVYLAGERADPDTIQWTMDKLG------VPVIDHWWQTETGWAIAANPMGIEHLPVKIG-----SPSVAMPGYDVQVLDVAPGTLGAIAVKLPGTLPNLWQAEERFVKSY-PGYYETGDAGYIEDGYLYIMARTDDVINVAGHRLSTGAMEEVLASHPDVAECAVIGVSDTLKLGFLCLSAGVNRPHDEIAKECVKLVREKIGPVAAFKLACVVDRLPKTRSGKILRGTMVNIADGTPWKMPATIDDPAILDEITEALGKLGYPAS 630
73 -48.8005ifi_A mol:protein length:694 Acetyl-coenzyme A synthetase  ali model follow..  15  111..AYNCLDRHYYKNPKKTAIIYEADEPSESREVSYEELMQETCRVANVLKSYGVKKGDAVSIYLPMTWQAAAAFLACARIGAIHSAVFAGFSAES-------LRDRVNDCECKVLITDAALQQCPLVENVLVLRRTGNKVPMTEGRDKWWDEECAKMPAYCPCERMASEDPLFILYTSGSTGKPKGVVHSTAGLLGTALTLKYVFDAHPDDRFIGWI-----TGHSYIIYGPLANGITTAVFESTPVYPTPSRYWDFVDKWKATQLYTAPTAIRLLRRM---GEDHVKNHDLSSLRVLGSVGEPINPEAWHWYNDFA---GKNQCAIVDTYWMTETGSISIAPLPGAISTKPGSATFPFFGMDVDIIDPQTGQVLEGNDVEGVLVAR-PSIARTVYRDHKRYLETY-PGYFFFGDGAARYDGYMWIKGRVDDVINVSGHRLSTAEVESALILHKGVAETAVVGCADDLTVTMKPEFDLKATKEADLSKELAIQVRKVIGPFAAPKKIYLVSDLPKTRSGKIMRRVLRKIVAGEGDQLGDLSSIADPQIVEEVKQKVTGSA.. 686
74 -48.3005jrh_A mol:protein length:660 Acetyl-coenzyme A synthetase  ali model follow..  15  78..AANCLDRHLQENGDRTAIIWEGDDTSQSKHISYRELHRDVCRFANTLLDLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEA-------VAGRIIDSSSRLVITADKNPNVTSVEHVIVLKRTGSDIDWQEGRDLWWRDLIEKASPEHQPEAMNAEDPLFILYTSGSTGKPKGVLHTTGGLVYAATTFKYVFDYHPGDIYVGWV-----TGHSYLLYGPLACGATTLMFEGVPNWPTPARMCQVVDKHQVNILYTAPTAIRALMAE---GDKAIEGTDRSSLRILGSVGEPINPEAWEWYWKKI---GKEKCPVVDTWWQTETGGFMITPLPGAIELKAG-------SATRPFFGVQPALVDQEGATEGNLVIT-PGQARTLFGDHERFEQTYFSTFYFSGDGARREDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIP-GQAIYAYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTSNL......................... 626
75 -46.4001ry2_A mol:protein length:663 acetyl-coenzyme A synthetase 1  ali model follow..  15  78..CYNCVDRHALKTPNKKAIIFEGDEPGQGYSITYKELLEEVCQVAQVLTSMGVRKGDTVAVYMPMVPEAIITLLAISRIGAIHSVVFAGFSSNS-------LRDRINDGDSKVVITTDESNRGGKVIETKRIVDDALRETPGVRHVLVYATEKKKYKTYYPCTPVDSEDPLFLLYTSGSTGAPKGVQHSTAGLLGALLTMRYTFDTHQEDVFIGWI-----TGHTYVVYGPLLYGCATLVFEGTPAYPNYSRYWDIIDEHKVTQFYVAPTALRLLKRA---GDSYIENHSLKSLRCLGSVGEPIAAEVWEWYSEKI---GKNEIPIVDTYWQTESGSHLVTPLAGGVTPMKP-------SASFPFFGIDAVVLDNTSHAEGVLAVKAPSFARTIWKNHDRYLDTYLNPYYFTGDGAAKKDGYIWILGRVDDVVNVSGHRLSTAEIEAAIIEDPIVAECAVVGFN-GQAVAAFVVLKNKDDELQDIKKHLVFTVRKDIGPFAAPKLIILVDDLPKTRSGKIMRRILRKILAG.............................. 631

FFAS is supported by the NIH grant R01-GM087218-01
1 3 9 8 0 4   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Jaroszewski L, Bierzynski A, Godzik A. Multiple model approach--dealing with alignment ambiguities in protein modeling. Pac Symp Biocomput. 1997;:328-39.