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Query: gi|15607144|ref|NP_214516.1| DNA polymerase III subunit beta (Rv0002) [Mycobacterium tuberculosis H37Rv], from M.tuberculosis

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDAATTRVGLTDLTFRLLRESFADAVSWVAKNLPARPAVPVLSGVLLTGSDNGLTISGFDYEVSAEAQVGAEIVSPGSVLVSGRLLSDITRALPNKPVDVHVEGNRVALTCGNARFSLPTMPVEDYPTLPTLPEETGLLPAELFAEAISQVAIAAGRDDTLPMLTGIRVEILGETVVLAATDRFRLAVRELKWSASSPDIEAAVLVPAKTLAEAAKAGIGGSDVRLSLGTGPGVGKDGLLGISGNGKRSTTRLLDAEFPKFRQLLPTEHTAVATMDVAELIEAIKLVALVADRGAQVRMEFADGSVRLSAGADDVGRAEEDLVVDYAGEPLTIAFNPTYLTDGLSSLRSERVSFGFTTAGKPALLRPVSGDDRPVAGLNGNGPFPAVSTDYVYLLMPVRLPGLast
1 -95.500[L] COG0592 DNA polymerase sliding clamp subunit (PCNA homolog)  ali follow..  24  1............MKFVVSRNELGNLIKKIQSVVPQNTPIPVLTHVLIETYNDELVFTATDLTVSTRCVTKAKVYEKGAISIPSKRFFQLVKELTEANLEISSAGEMAQITSGSSCFRLLSMEKEDFPMLPDIQNARFSLPAEQLKTMLQRTSFAVSREESRYVLTGVLLAIANGVATIVGTDGKRLAKIDAEVTLDK-SFSGEYIIPIKAVEEIIKMCSDEGEAAIFL-------DQDKIAVECDNTLLITKLLSGEFPDFSPVISTESNVKLDLHREELITLLKQVALFTESSHSVKFSFLPGELTLTANCTKVGEGKVSMAVNYSGELLEIAFNPFFFLDILKHSKDELVSLGISDSYNPGIITD--------------------SASGLFVIMPMRLHD 365
2 -11.100[DL] KOG2810 Checkpoint 9-1-1 complex, RAD9 component  ali follow..  13  2.......................................................................................................................................KYTLEGSNAR-VIAKAVQSLSK-----VGKEMFIEIDQQSLQMRAINATQSAVGSISFKRSPPHSDFYCKISMKGCLAVFRNMNEVEYCELNLLD-----NQTNLQVNLRCKLETTKEATISIIDDQNI-TDQMPNIIRGDHKLLTDISNNFNSSEEE---LTLEANSGSVVAKNYIEGARVNDKFMRTQLKTKETVITFCIKEFRAFLLFAENASLTLEFDEAGMPFLLK.................................... 242
3 -10.600[L] KOG1636 DNA polymerase delta processivity factor (proliferating cell nuclear antigen)  ali follow..  13  8...........................................................................................................................................QGSLLKKVLESI---------KDLVNDANFDCSSTGFSLQAMDSSHVALVSLLLRSEG-DRNLSMGMNLGNMSKMLKCAGNDDIITIKADDGGDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPDAEYHSIVRMPSNEFSRICKDLSSIGDT---VVISVTKEGVKFSTAGDTTVDKPEDAIVIEMKEPVSLSFALRYMNSFTKATPSDTVTISLSSE-LPVVVE-----------------KVAEMGYIRYYLAP..... 253
4 -8.240[DL] KOG3194 Checkpoint 9-1-1 complex, RAD1 component  ali follow..  8  8...........................................................................................................................................CLKQIQSTLRCIDFS---KECTIEITGLRFAVEESQSLQAHAFLDKSLFQTFNFQGDSDGDTYMFQTMISPLLQSLSIYTDGKERISTSAWDQPTVNIMKVQYNGPGCPFIWEVEEMAGYATACELASTLCTKIIMKSNWLYDALVELDNNMGENLIIHTSSQKSTFLLRCVGAEYPNEKSVLESFETDSENTYSYRFSLIRHALKALQGSKVNLRIDENGTLSIQIMLVGQEGLCTFVD-------------FCIVPL.... 280
5 -5.400[K] COG0195 Transcription elongation factor  ali follow..  12  2..................NSEFMDALTTLEKGISKEVIIEAIEAALISGYKRNFN-QAQNVRVDVN-------RENGSIRVFARK--EVVEEVFDARLEISLDEKGINPNYEVDDVVEIEVTPKDFGRIAAQTAKQVVT--QRVREAERGIIYADFIDREEDIMTGIVQRQDNRFIYV----------------------KVEALLPLSEQMP-NESYRHNDRIKAYITKVEKTTKGPQIMISRTHPGLLKRLFELEVPEIYD------------------GTVELKSVAREAGDRSKISVHAENPEVDPVGACVGPKGSRVQTELKGEKIDI---VEYVANALSPSKVVKVNVNEEEKTTQVIVPDYQ................................. 312
6 -4.040[DL] KOG3999 Checkpoint 9-1-1 complex, HUS1 component  ali follow..  12  11.................................................................................................................................................YTLTRLVQALDK-----IGRFCWLRLMPETVNFVIVPDFRMTQVWSVLEQSNADNVINLEVPIDNFYKALRSAANASDSTVRLSKKN------SLSTTWSGRAFGSNIVTHNIP--EPTAPEPDCHIFLPQLNFLRHVVDKIIMSANMSGELQLSVNIPSARVSTPSQVEDISRHPSQTRAPEEFVHMRLDSKDLVNMLKISSVAKRVIACFCEGHALVL..................................... 263
7 -3.790[ABO] KOG1446 Histone H3 (Lys4) methyltransferase complex and RNA cleavage factor II complex, subunit SWD2  ali follow..  13  26.........................................INAIDFAPNGEHLISCSEDDQIVIYDCEKGTQSRT--------------KKYGVDLIHFTHANNTAIHSSTKVDDTIRYLSLHDNKYLRYFPGHTKKVISLCISP--EDTFLSGSLDKTLRLWD--LMHLSGRPIAAYDPEGLIFAAGVNSESIKLYDLRSFDKGPFVTFKLNQEKECD-----------------TGLKFSRDGKTILISTNGSVIRLVDA---FHGTPLQTFTGYPNNKGIPIEASFSPDSQFIFSGSTDGRVHI---NADTGNKVSVLNGDHPGPVQCVQFNPKYMM............................................................. 298
8 -3.720[U] KOG1332 Vesicle coat complex COPII, subunit SEC13  ali follow..  9  2.........................VSVINTVDTSHEDM--IHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPM-------YGNILASCSYDRKVIIWREENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISL----YTGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAPSIGLPTSTIASCSQDGRVFITCDDASSNTWSPKLLHKFNDVVHVSWSITANILAVSGGD........................................................................................ 283
9 -3.700[U] COG5167 Protein involved in vacuole import and degradation  ali follow..  10  434............................................VTRDNRIGVFKTDDEDDSLEFVAAIKNISNLGGKSIDPHK-------------PMLYMEDRNLILTDGENENKLYKMDIERGKVIEEWSTGDKNVVQ-----------YGPTKKFDQMTPEQTIVGVSQKGVFKIDP---RINGKNKIAVDESKDYVGKYNFSSIGTTESGYIAIGSEKGDIKLYDRLGIRAKTAIPSLGQAIKFITTSADGKWESTLLLMDLKIKDGKNAGNIGFLKSFPYVLKIRPEHSASILTYTKKPIRFTKAYFNTGIGQQEQTIVTSTGPYAISWSLKGILNQIRRYNADVVADNFEFGSDKKVIVALKDD............................... 754
10 -3.700[U] KOG2395 Protein involved in vacuole import and degradation  ali follow..  10  434............................................VTRDNRIGVFKTDDEDDSLEFVAAIKNISNLGGKSIDPHK-------------PMLYMEDRNLILTDGENENKLYKMDIERGKVIEEWSTGDKNVVQ-----------YGPTKKFDQMTPEQTIVGVSQKGVFKIDP---RINGKNKIAVDESKDYVGKYNFSSIGTTESGYIAIGSEKGDIKLYDRLGIRAKTAIPSLGQAIKFITTSADGKWESTLLLMDLKIKDGKNAGNIGFLKSFPYVLKIRPEHSASILTYTKKPIRFTKAYFNTGIGQQEQTIVTSTGPYAISWSLKGILNQIRRYNADVVADNFEFGSDKKVIVALKDD............................... 754
FFAS is supported by the NIH grant R01-GM087218-01
1 4 5 2 0 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Jaroszewski L, Godzik A. Domain analysis of the tubulin cofactor system: a model for tubulin folding and dimerization. BMC Bioinformatics. 2003 Oct 10;4(1):46.