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Query: gi|15607158|ref|NP_214530.1|(removed signalp:1-30) penicillin-binding protein PbpA (Rv0016c) [Mycobacterium tuberculosis H37Rv], from M.tuberculosis

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst ADGLRADPRNQRVLLDEYSRQRGQITAGGQLLAYSVATDGRFRFLRVYPNPEVYAPVTGFYSLRYSSTALERAEDPILNGSDRRLFGRRLADFFTGRDPRGGNVDTTINPRIQQAGWDAMQQGCYGPCKGAVVALEPSTGKILALVSSPSYDPNLLASHNPEVQAQAWQRLGDNPASPLTNRAISETYPPGSTFKVITTAAALAAGATETEQLTAAPTIPLPGSTAQLENYGGAPCGDEPTVSLREAFVKSCNTAFVQLGIRTGADALRSMARAFGLDSPPRPTPLQVAESTVGPIPDSAALGMTSIGQKDVALTPLANAEIAATIANGGITMRPYLVGSLKGPDLANISTTVGYQQRRAVSPQVAAKLTELMVGAEKVAQQKGAIPGVQIASKTGTAEHGTDPRHTPPHAWYIAFAPAQAPKVAVAVLVENGADRLSATGGALAAPIGRAVIEAALQGEPLast
1 -94.700[M] COG0768 Cell division protein FtsI/penicillin-binding protein 2  ali follow..  24  131...........TSIAVKTPLTEVQVARFAVNQFRFPGIEVKGYQRRFYPYGSALTHVIGYVSKIIGKLGIERYYESTLHGKTGNNRGRVIRQLHEQPPQAGKDIYLTLDLSLQIYIEKLL-----SGSRAAVVVTDPRTGGILALVSNPSYDPNLFVDG---ISNKDYQGLLNDTNRPLINRATQGVYPPASTVKPYIAVSALSAGVITKNTLFDPGWWQLPGSE---KRYRDWKKWGHGRLNVTKALEESADTFFYQVAYDMGIDRLSSWMSKFGYG---EYTGIDLSEERAGLMPTREWTIPVGIGQGYWTATPIQMAKSLMTLINDGTVKTPHLLQSTRIDGVLVPYKQEDSTQIGSINSGYWEIAKDGMYGVANGTGRKFEGTPYKAAAKSGTAQVYSYETHLRDHKLMVAFAPYENPTVSVAIILENGG------AGPAVGTITRQILDHILLGDN 614
2 -46.500[V] COG2602 Beta-lactamase class D  ali follow..  14  8..................................................................................................................................VLVLSIAGIGGFSVHAASSAHEKHLNVSKMNVDDEFKLHDLQKDQTFVYNRKRANQRQTPQSTFKVVNALIGLQVKAVRDEYDVKRWD-----------GVKREFESWNRDHTLGSAMRESAIWYYQALARDIGEERMKTWLHTLSYGNEDISGGID-----------------QFWLQSSLTISPLEQETFLEKLAKEEL----------------------------PFDKPVMKIVKRMMIQEEG--------DHYTLYGKTGTRLTD------MGLGWFVGFIKTEHGSYVFVTNVDD--------SGTKAKNITVDILKKY..... 262
3 -44.800[M] COG0744 Membrane carboxypeptidase (penicillin-binding protein)  ali follow..  22  242.....KLAQQKQKEVLGRMLELDWITQKEYDDALKEELTFGRIKSFQGSALPYITTVSQELAKKFGRETLLK---------------------------GGMRVQTTVDANFQTMAEDTVKKWHLSRNQIALVAIDPRTHFVKALVGGVDSRASEF------------------------NRATQALRQPGSSFKPFVYYAAFATGKFAPDSTVIDAPVRYRDGNNWYS--RNYDGGFSGAMSIRTALAQSRNIPVIKLGKTIGMNKVVETCRILGIMSPMEP--------------------VTSLPLGAIGVTPLEMASAYATFANYGWQSPPTVIARITDSSGNVLLDNTPKP-QLVLDPWASAAIIDVMRSVVTNGTGKGAAIDRPSAGKTGTTSSEKD-------IWYVGTV----PQLTTAVWIDNRQLASGATGGGKVAPIWRDFMTKALKGVP 624
4 -34.300[M] COG5009 Membrane carboxypeptidase/penicillin-binding protein  ali follow..  17  224.....DRAIARRNVVLSRMLSEGYITQAQYDQARSEPIDANYHAPEIAFSAP-------YLSEMVRQEMYNRYGESAYED--------------------GYRIYTTITRKVQQAAQQAVRNNVLDYDMSALVSLNPQTGAVLALVGGFDFNQSKF------------------------NRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISRWDAGAGSDWRPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESL-----------------ALGSAS--FTPMQVARGYAVMANGGFLIDPYFISKIENDQGGVIFEAKPKIAPHVINTPLAFLIKSALNTNITGWRAARDLKRRDIGGKTGTTNSSKD-------AWFSGYGPFDDHRRDLGRTTASGA-SGYEGGAKSAQPAWDAYMKAVLEGVP 797
5 -31.400[M] COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC  ali follow..  13  105.QDLTSGRVISGGSTLTMQVARLLDPHPKTFGGKIRQLWRALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYSEAAMLAVLPQAPSDKITTTLDAGLQRRLEELAQNRLPPRSSLAMIVVDHTDMRVRGWVGSVDLNDDSRFG---------------------HVDMVNSIRSPGSVLKPFVYGLALDEGLIHPASLLQDVPRRTGDYR------GNFDSGFHGPISMSEALVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYLP--------------NGAAPNLSLILGGAG--AKLEDMAAAYTAFARHGKAGKLRLQPD------------DPLLERPLMSSGAAWIIRRIMADEAQPLPDSALPRVAPLAWKTGTSYGYRD-------AWAIGV----NARYVIGIWTPDGTPVVGQFGFASAVPLLNQVNNILLSRSA 569
6 -13.600[V] COG2367 Beta-lactamase class A  ali follow..  13  1.........................................................................................................MKLNRKMTMTVAEQLNAICDVPFVTRFMVRNLLTGEEIGRGE-------------------------------------NEETPSGSTRKTSIMMAVLKA--ASEGRIDLDQPVTYEKRLAEEVASGMFRYMTPGVISLRDMMVLSDNVCTKMVLERLTLEEVDGYCKSLGMANTHHRFLIPPLALAADHPLKTVTT-----------TSAADQVLLLQTILDA--------------------QSSPEAQAKLGCSPQLCEWAMQTLKNQILRYGIRSRLPEAMVASKSGRGKRGRMD---------IVYRN-GAPSFIITTYTDEDGTPGYTIALETIGRLAQACWDGF..... 286
7 -7.220[S] COG5445 Predicted secreted protein  ali follow..  16  9.............................................................................................................................................LLALVTLPT-EETPLQLVLRGAQHDQLYQLSSSGVTKVSALPDSLTTPLGSLWKLYVYAWLEDTHQPEQP-------YQCRGNSPE----EVYCCQAGESITRDTALVRSCGLYFAPQRLHIGADVWGQYWQQRQ---------------------APAWLASLTTLKPETSVTVKSLLDSLATLPAQ-NKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTDGT--PLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKITAEKSTTAV............... 279
8 -5.430[M] COG1686 D-alanyl-D-alanine carboxypeptidase  ali follow..  13  12.......................................................................................................LLVLFIAPTAGWAAESMVPAPPQLAAKSYVLMDGESGQVL------------------------------------VENNGDQRLPPASLTKLMTAYIEIEAGRIGENDLVTVS--------------EHAWRTGGSRMFIKVGSQVSVSDLLHGIIIQSGNDASVALAEHIAGSEDAFADMMNTTAQKLG-LTNSHFMDATGLPNPDHYSSARDMAVLARAIIYG-----PSHYAIYAQKEFLWNNIKQPNRNLLLWRDKTVDGL------------------------KTGHTDEAG----------LVASAVRDGQRMIAVVF--------GTNSEQARAAETQKLLTYGFRF.. 275
9 -5.340[A] KOG0124 Polypyrimidine tract-binding protein PUF60 (RRM superfamily)  ali follow..  12  1............................................................................................MATATIALQVNGQQGGSEPAAAAAVVAAGDKPPQGTDSIKMENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQRQ----------------------------------RALAIMCRVYVGSIYYELGEDTIRQAFAPFG-----PIKSIDMSWDSVT---------MKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNI--KVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSV----FEAFGKIKSCTLARDPTTGKHKGYFIEYEKAQSSQDAVSSM-----NLFDLGGQYLRVGKAVT.......... 304
10 -5.300[C] KOG0069 Glyoxylate/hydroxypyruvate reductase (D-isomer-specific 2-hydroxy acid dehydrogenase superfamily)  ali follow..  12  150...................................................EIRDSVIGFFG--FGGISQAIAYHTRTRKENDGDFKAEHVSFEQLLQESD---FLVVAAPLTNETREKFNGKAFNLMKRSSVFVNVARGGLDVTTPEPLPANSPLLNVPNCEGLKMSTTKPFKVLIAHTDVPPEGIEPPKNRPEILEKIRGAHAVIWGGRDILNAEILDAAGPQLKA----STMSSGINNVDVPELKKRGIPLMLTVAVADLTVGLLIAAARRFQEGRRKIDLGQDIRDSTVGFY---------GFGGGQAVAKRLMGFDIKRMLYTTRNRVSQDIEERFAESDFLIIASPLTKETLGLFNATVFNKMKETAVLVNVGRGKIVNQDDLYEALKSNRIFAAGLDVMDPE-------LPSNDKLLTLVVVTPHVGYATRRTRVDAANLASRNVL-KGLAGEP 592
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Alonso A, Sasin J, Bottini N, Friedberg I, Friedberg I, Osterman A, Godzik A., Hunter T, Dixon J, Mustelin T. Protein tyrosine phosphatases in the human genome. Cell. 2004 Jun 11;117(6):699-711. Review.