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Query: gi|15607160|ref|NP_214532.1| serine/threonine phosphatase (Rv0018c) [Mycobacterium tuberculosis H37Rv], from M.tuberculosis

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MARVTLVLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPGGDLLAKLDAAVRAGNSAIAAQVEMEPDLEGMGTTLTAILFAGNRLGLVHIGDSRGYLLRDGELTQITKDDTFVQTLVDEGRITPEEAHSHPQRSLIMRALTGHEVEPTLTMREARAGDRYLLCSDGLSDPVSDETILEALQIPEVAESAHRLIELALRGGGPDNVTVVVADVVDYDYGQTQPILAGAVSGDDDQLTLPNTAAGRASAISQRKEIVKRVPPQADTFSRPRWSGRRLAFVVALVTVLMTAGLLIGRAIIRSNYYVADYAGSVSIMRGIQGSLLGMSLHQPYLMGCLSPRNELSQISYGQSGGPLDCHLMKLEDLRPPERAQVRAGLPAGTLDDAIGQLRELAANSLLPPCPAPRATSPPGRPAPPTTSETTEPNVTSSPASPSPTTSAPAPTGTTPAIPTSASPAAPASPPTPWPVTSSPTMAALPPPPPQPGIDCRAAALast
1 -67.200[T] COG0631 Serine/threonine protein phosphatase  ali follow..  29  401LSVQLSSLEDAGRTDVGRQRHHNEDYFGIETGLYILCDGMGGHAGGEVASELAVITLRQYFQQDNQLPAEEIIRESVYLANQAIYEKNQQESGVGRMGTTLVMLLVQGSQAAVAHVGDSRLYRVRKRGLEQVTVDHEVGQREIDRG-VEASIAYARPDAYQLTQALGPRDINPSVEFFDINEDSLLVLASDGLSDTNWQTHLLPLLSSSNLEQGVAELIDLANQYNGHDNITAILVRAKVRPNLGEET.......................................................................................................................................................................................................................................................................... 678
2 -43.300[T] KOG1379 Serine/threonine protein phosphatase  ali follow..  17  43.PELSLSVGIHAIPHPDKVEKGGEDAFFVSSYVMAVADGVSGWAEQDVDPSLFSKELMANASRLVDDQ------EVRYDPGFLIDKAHTATTSRGSATISILAMLEEVGILKIGNVGDCGLKLLREGQIIFATAPQEHY----------------DCPYQLSSEGSAQTLDASQFSIVEVQKGDVIVMGSDGLFDNVFDHEIVSIVTKFGITITARLLAEVASSHSRDTEFESPYALEARAK................................................................................................................................................................................................................................................................................ 278
3 -29.200[T] KOG0697 Protein phosphatase 1B (formerly 2C)  ali follow..  20  22.......LRYGLSSMQG--RVEMEDAHTASWSFFAVYDGHAGSQVAKYCCEHLLDHITNNQDAPSVENVKNGIRTGFLEIDEHMRVMSEKKHGADRSGSTAVGVLISPQHTYFINCGDSRGLLCRNRKVHFFTQDHK--SNPLEKERIQNAGGSVMIQR-AVSRALGDFDYEPEVHDIERSEED-IILACDGIWDVMGNEELCDFVRSDDLEKVCNEVVDTCLYKGSRDNMSVILICFPNAPKVSPE........................................................................................................................................................................................................................................................................... 300
4 -28.700[T] KOG0698 Serine/threonine protein phosphatase  ali follow..  16  22.......YRVGSSCMQG--RVDMEDAHTHQAAFFAVYDGHGGASVAKYAGKHLHKFITK-RPEYRDNSIEVALKKAFLDFDREMLQNGSLDEQTA--GCTAIVVLIRERRLYCANAGDSRAIACISGMVHALSVDHK--NDAKESKRIMASGGWVEFNR-ALSRALGDFIYKPDVEVLDITEDLEFVLACDGIWDVMSNFEVCQFVHKMEPELICEELMNGHTGNVGGDNMTVILVCLLHNKSYEDLAVRCGGKRKTPVETVGDIQDQSVKVVTPCSQGSSGSSTSR................................................................................................................................................................................................................................... 335
5 -25.300[T] KOG1323 Serine/threonine phosphatase  ali follow..  22  125...................LPNGEGLQLKSCHYWSLFDGHAGSGAAVVASRLLQHHITEQLQDPHECLVIGALESAFKEMDLQIERERSSYNISG--GCTALIVICLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETELYRDFNMTGWAYKTIEDEDLVTRGLGDHDLKPEVRIYDLSKDDVLILATDGLWDVLSNEEVAEAITQHRYTLAAQDLVMRARRLGSGDDISVYVIPLIHGNKLS............................................................................................................................................................................................................................................................................. 514
6 -23.400[T] KOG0700 Protein phosphatase 2C/pyruvate dehydrogenase (lipoamide) phosphatase  ali follow..  20  347................................WWRCEWDRESQDLDRRLKEQISRRSGS-DRLTNHSEVLEALSQALRKTEEAYLDTADKNPELALMGSCVLVMLMKGEDIYVMNVGDSRAVLGQKSEAFQLTVDHS-VERIRNEHPDDVTAVTNERVKGSLTRAFGAGFLKPSLYHHRLGSKDRFLLSSDGLYQYFTNEEAVSEVELQPEGDPAQHLVQELLRRRYHDDVSIVVISLEGRMWKSC............................................................................................................................................................................................................................................................................ 661
7 -9.890[TK] COG2208 Serine phosphatase RsbU, regulator of sigma subunit  ali follow..  10  39..................STIFNGDLIVVGGVYVMIADATGHGLPAAISTIPATRTFFSTAQKGLS------LGEMVIELNHSLERFLPVG-----LAASVFEVRANGFEISWWGGGLPEAYLLDHHG----------------------NIVSRLISNHMPLGVLPSNEFEADVQHFKLEPNQKLVCYTDGIIEYFGQERLEHVLTKAYSEALIPTLYDAVKKFSNRDDLSILTMTFPITNSNSSDK.......................................................................................................................................................................................................................................................................... 252
8 -7.090[R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)  ali follow..  8  531.......................................................................................................................................HTETCLPVHPKELDIDSEGEQKTIQMIDEFSDVNEGEKELMKL-----NLHVIVRKNLYGLIAAETVYKTVQLLSKYAAGQELMQRQREEQLKYWLDVGMHKKQEDPKTLKSPQKPAPPADQASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGVQSKGTENGTNGSNSSSSNSKNVAKKSADQP---SEYGQKRNVSGSRLAATPASKRKLSSKDVEQAADAPEVLTHSDNAVDVGIIDDECGGFGAVGVMNGVASPVANNSEMDTEAEVEAEPTATKAITIHCQQPVTTPVAAAATANERLPGVAPHRRGPRRADRREEELVASAPGYRCRPSMRGADAGAAAAAAAAPTHPHPHRPPPPPPP........ 954
9 -6.880[F] KOG3079 Uridylate kinase/adenylate kinase  ali follow..  19  46..............................................................................................AGKGTQCARIV---EKYGYTHLGE----LLRDERKNPDSQYGELIEKYIKEGKIVPVEITI----SLLKREMDQTMAANA-------QKNKFLI--DGFPRNQDNQGWNKTMDGKNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPII........................................................................................................................................................................................................................................................................ 195
10 -6.250[R] KOG1280 Uncharacterized conserved protein containing ZZ-type Zn-finger  ali follow..  10  378....KATFTEAMFCSMLADEELFQPPIGLPWTANFMLDAV--EPSGSVKSNGKLLLYPVKTKELMERFYRGLAEYKTWIGYQTEPTAESKATELPSASTSSAYFTVLGD----IPYADSGSDDLESNASEEMASEVMYCGQCFDEGR-TETHKDDRRIKIIYHRS-GEKLLNGDASKS---------FCKKRFS----AEELQLHLSEMHSNPADASAL-ERMRQEDLENR........................................................................................................................................................................................................................................................................................... 643
FFAS is supported by the NIH grant R01-GM087218-01
1 4 3 9 1 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Alonso A, Sasin J, Bottini N, Friedberg I, Friedberg I, Osterman A, Godzik A., Hunter T, Dixon J, Mustelin T. Protein tyrosine phosphatases in the human genome. Cell. 2004 Jun 11;117(6):699-711. Review.