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Query: gi|15675969|ref|NP_273095.1| glycerate dehydrogenase (NMB0029) [Neisseria meningitidis MC58], from N.meningitidis

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNHKKIVVLDADTLPGRVFHFDFPHELAVYGTTGADETAERVRDAHIVITNKVMISADIIAANPQLELIAVSATGVNNVDIGAAKAAGVAVCNVRAYGNESVAEHAFMLMIALMRNLPAYQRDVAAGLWEKSPFFCHYGAPIRDLNGKTLAVFGRGNIGRTLAGYAQAFGMGVVFAEHKHASAVREGYVSFEDAVRAADVLSLHCPLNAQTENMIGENELRQMKPGAVLINCGRGGLVDENALLAALKYGQIGGAGVDVLTNEPPKNGNPLLNARLPNLIVTPHTAWASREALDRLFDILLANIHAFVKGEAQNRVVLast
1 -75.500d1ygya1 c.2.1.4 (A:99-282) Phosphoglycerate dehydrogenase {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  35  1.................................................................................................NIHSAAEHALALLLAASRQIPAADASLREHTWKRSSFSG------TEIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYDPYVSPALGIELLSLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGLDVFATEPCT-DSPLF--ELAQVVVTPHLG............................... 184
2 -74.700d2naca1 c.2.1.4 (A:148-335) Formate dehydrogenase {Pseudomonas sp., strain 101 [TaxId: 306]}  ali model 3D-neighbors follow..  28  2....................................................................................................SVAEHVVMMILSLVRNYLPSHEWARKGGWNIADCVSH----AYDLEAMHVGTVAAGRIGLAVLRRLAPFDVHLHYTDRHRLPESVEKHATREDMYPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARALESGRLAGYAGDVWFPQPAPKDHPWR--TMPYNGMTPHIS............................... 187
3 -74.100d1sc6a1 c.2.1.4 (A:108-295) Phosphoglycerate dehydrogenase {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  33  1.................................................................................................NTRSVAELVIGELLLLLRGVPEANAKAHRGVGNKLAAGS------FEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIENPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALADALASKHLAGAAIDVFPTEPATNSDPFTSAEFDNVLLTPHIGG.............................. 188
4 -73.600d1mx3a1 c.2.1.4 (A:126-318) Transcription corepressor CtbP {Human (Homo sapiens), Ctbp1 [TaxId: 9606]}  ali model 3D-neighbors follow..  34  1...................................................................................................EETADSTLCHILNLYRRATWLHQALREGTRVQSEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSSQGPLK--DAPNLICTPHAAW.............................. 193
5 -71.700d1gdha1 c.2.1.4 (A:101-291) D-glycerate dehydrogenase {Hyphomicrobium methylovorum [TaxId: 84]}  ali model 3D-neighbors follow..  27  2..................................................................................................TVATAEIAMLLLLGSARRAGEGEKMIRTRSWPGWEPLELVG---EKLDNKTLGIYGFGSIGQALAKRAQGFDMDIDYFDTHRASSQATFHDSLDSLLSVSQFFSLNAPSTPETRYFFNKATIKSLPQGAIVVNTARGDLVDNELVVAALEAGRLAYAGFDVFAGEPNINEGYY---DLPNTFLFPHIGSA............................. 191
6 -68.200d1qp8a1 c.2.1.4 (A:83-263) Putative formate dehydrogenase {Pyrobaculum aerophilum [TaxId: 13773]}  ali model 3D-neighbors follow..  26  1..................................................................................................ADAVAEFALALLLAPYKRIIQYGEKMKRGDYGRD-------VEIPLIQGEKVAVLGLGEIGTRVGKILAALGAQVRGFSRTPKEGPWRFTNSLEEALREARAAVCALPLNKHTRGLVKYQHLALMAEDAVFVNVGRAEVLDRDGVLRILKERPQFIFASDVWGRNDFAKDAEFF--SLPNVVATPWVA............................... 180
7 -65.100d1j4aa1 c.2.1.4 (A:104-300) D-lactate dehydrogenase {Lactobacillus helveticus [TaxId: 1587]}  ali model 3D-neighbors follow..  28  2...................................................................................................NAIAEHAAIQAARILRQDKAMDEKVARHDLRWAPTIG------REVRDQVVGVVGTGHIGQVFMQIMEGFGAKVITYDIFRNPELGYYVDSLDDLYKQADVISLHVPDVPANVHMINDESIAKMKQDVVIVNVSRGPLVDTDAVIRGLDSGKIFGYAMDVYEGEVDARLADLI--ARPNVLVTPKTAF.............................. 197
8 -40.300d1mx3a2 c.23.12.1 (A:28-125,A:319-352) Transcription corepressor CtbP {Human (Homo sapiens), Ctbp1 [TaxId: 9606]}  ali model 3D-neighbors follow..  14  2....LVALLDGRDCTEMPILKDVATVAFCDAQSTQEIHEKVLNEAVALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVXYSEQASIEMREEAAREIRRAITGRIPDSLKNC......................................................................................................................................................................................... 131
9 -40.200d1sc6a2 c.23.12.1 (A:7-107,A:296-326) Phosphoglycerate dehydrogenase {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  19  2KDKIKFLLVEGVHQKALESLRAAGYTNIEFGALDDEQLKESIRDAHFILRSRTHLTEDVINAAEKLVAIGAFAIGTNQVDLDAAAKRGIPVFNAPFSXSTQEAQENIGLEVAG-KLIKYSDNGSTLSAVN........................................................................................................................................................................................... 133
10 -40.200d1ygya2 c.23.12.1 (A:3-98,A:283-316) Phosphoglycerate dehydrogenase {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  20  1.SLPVVLIADKLAPSTVAALGD-QVEVRWVDGPDRDKLLAAVPEADALLRSATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSXASAEAQDRAGTDVAESVRLALAGEFVPDAVNV........................................................................................................................................................................................... 130
11 -36.300d1dxya2 c.23.12.1 (A:1-100,A:300-330) D-2-hydroxyisocaproate dehydrogenase {Lactobacillus casei [TaxId: 1582]}  ali model 3D-neighbors follow..  15  1...MKIIAYGARVDEIKQWAKDTGNTLEYHTEFLDENTVEWAKGFDGISLQTTPYAAGVFEKMHGIKFLTIRNVGTDNIDMTAMKQYGIRLSNVPAYXTETAVHNMVYFSLQHLVDFLTKGETSTEVT............................................................................................................................................................................................. 131
12 -35.600d1j4aa2 c.23.12.1 (A:2-103,A:301-332) D-lactate dehydrogenase {Lactobacillus helveticus [TaxId: 1587]}  ali model 3D-neighbors follow..  19  2....KIFAYAIREDEKPFLDAHKDVEVEYTDKLLTPETVALAKGADGVVYQQLDYIAETLQALADITKMSLRNVGVDNIDMAKAKELGFQITNVPVYSXYTTHAVRNMVVKAFDNNLELVEGKEAETPVK........................................................................................................................................................................................... 134
13 -31.400d1qp8a2 c.23.12.1 (A:1-82,A:264-302) Putative formate dehydrogenase {Pyrobaculum aerophilum [TaxId: 13773]}  ali model 3D-neighbors follow..  14  1...MELYVNFELPPEAEEELRK----------YFKIVRGGDLGNVEAALVSR--ITAEELAKMPRLKFIQVVTAGLDHLPWESIPP-HVTVAGNAGSNXGYGNERVWRQMVMEA--------------------------------VRNLITYATGGRPRNIAKREDYIG................................................................................................................................................... 122
14 -30.800d1gdha2 c.23.12.1 (A:2-100,A:292-321) D-glycerate dehydrogenase {Hyphomicrobium methylovorum [TaxId: 84]}  ali model 3D-neighbors follow..  19  1..KKKILITWPLPEAAMARARES-YDVIAHGDITIDEMIETAKSVDALLTLNEKCRKEVIDRIPNIKCISTYSIGFDHIDLDACKARGIKVGNAPHGXATQAREQANDLIDALFGGADMSYALA................................................................................................................................................................................................. 130
15 -29.800d2naca2 c.23.12.1 (A:1-147,A:336-374) Formate dehydrogenase {Pseudomonas sp., strain 101 [TaxId: 306]}  ali model 3D-neighbors follow..  15  45..TPGQLLGSVSGELGLKYLESNGHTLVVTSDKPDSVFERELVDADVVISQPAYLTPERIAKAKNLKLALTAGIGSDHVDLQSAIDRNVTVAEVTYCNSXTTLTAQARYAAGT-REILECFFEGRPIRDEYLIVQG..................................................................................................................................................................................... 183
16 -28.300d1li4a1 c.2.1.4 (A:190-352) S-adenosylhomocystein hydrolase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  21  21...............................................................................................................................................MIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALGYEVTTMDEACQEGNIFVT----TTGCIDIILGRHFEQMKDDAIVCNIGHFVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNL...................................... 158
17 -20.600d1kjqa2 c.30.1.1 (A:2-112) Glycinamide ribonucleotide transformylase PurT, N-domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  13  8...............................................................................................................................................RPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMINMLDGDALRRVVELEKPHY-IVPEIEAIATDMLIQLEEEGLNVVPCARATKLTM............................................................................. 111
18 -13.600d4ypoa1 c.2.1.0 (A:1-180) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  15  12................................................................................................................................................IQGRKVGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRGLDVDTPAEVAKWADVVMVLAP-DTAQAEIFAGDIEPNLKPGDALFFGHGLNVHFGLIKPPADVA.................................................................... 121
19 -11.800d2pv7a2 c.2.1.6 (A:92-243) Prephenate dehydrogenase TyrA {Haemophilus influenzae [TaxId: 727]}  ali model 3D-neighbors follow..  17  1..........................................................................................................................................GFKTINSDIHKIVIVGYGKLGGLFARYLRASGYPISILDREDWAVA-------ESILANADVVIVSVPINLTLETI--ERLKPYLTENMLLADLTSVKREPLAKMLEVHTGAVLGL--------------HPMFGADIASVVRCDGRFPERYEWLLEQIQIWGAKIYQ........... 151
20 -11.600d1saya1 c.2.1.4 (A:136-303) L-alanine dehydrogenase {Phormidium lapideum [TaxId: 32060]}  ali model 3D-neighbors follow..  22  30................................................................................................................................................VKPGKVVILGGGVVGTEAAKMAVGLGAQVQIFDINVERLSYLETLEIETAVAEADLLAVLVP-GRRAPILVPASLVEQMRTGSVIVDVAQGGCVE.............................................................................. 140
21 -10.900d1l7da1 c.2.1.4 (A:144-326) Nicotinamide nucleotide transhydrogenase dI component {Rhodospirillum rubrum [TaxId: 1085]}  ali model 3D-neighbors follow..  18  27................................................................................................................................................VPPARVLVFGVGVAGLQAIATAKRLGAVVMATDVRAATKEQVESLAVLKELVKTDIATALIP-GKPAPVLITEEMVTKMKPGSVIIDLAAGGNCPLSEPGKIVVKHGVKIVGHTNVPSR...................................................... 183
22 -10.900d4dlla1 c.2.1.0 (A:29-190) automated matches {Polaromonas sp. [TaxId: 296591]}  ali model 3D-neighbors follow..  16  2.................................................................................................................................................YARKITFLGTGSMGLPMARRLCEAGYALQVWNRTPARAASLAALQARAAARDADIVVSMLENGAVVQDVLAQGVAAAMKPGSLFLDMASITPREARDHAARLGALGIAHLDTPVSGGTVGAEQGTL.............................................. 134
23 -10.600d2cvza2 c.2.1.6 (A:2-157) Hydroxyisobutyrate dehydrogenase {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  13  1...................................................................................................................................................EKVAFIGLGAMGYPMAGHLARRFPTLVWNRTFEKAEEFGSEAVPLERVAEARVIFTCLPTTREVYEVAEA--YPYLREGTYWVDATSGEPEASRRLAERLREKGVTYLDAPVSGGTSGAEAGTL.............................................. 127
24 -10.500d4gwga1 c.2.1.0 (A:1-176) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  18  3...................................................................................................................................................ADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFGAQSLKEMVSKLKKPRRIILLVKAGQAVDDEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMP........................................... 142
25 -10.500d3etja2 c.30.1.1 (A:1-78) N5-carboxyaminoimidazole ribonucleotide synthetase PurK (AIRC), N-domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  20  2...................................................................................................................................................KQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDA---------EPAAVPFQQSVITAE................................................................................................................. 49
26 -10.500d5je8a1 c.2.1.0 (A:1-163) automated matches {Bacillus cereus [TaxId: 226900]}  ali model 3D-neighbors follow..  16  2...................................................................................................................................................KKIGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEAEASFEKESISKLAETCDVVFTSLPSPRAVEAVYFGAEFENGHSNVVFIDTSTVSPQLNKQLEEAAKEKKVDFLAAPVSGGVIGAENRTL.............................................. 133
27 -10.300d3g0oa1 c.2.1.0 (A:6-169) automated matches {Salmonella typhimurium [TaxId: 602]}  ali model 3D-neighbors follow..  16  1..................................................................................................................................................DFHVGIVGLGSMGMGAARSCLRAGLSTWGADLNPQACANLLAESAREFAGVVDALVILVVNAAQVRQVLFGEDAHLMKPGSAVMVSSTISSADAQEIAAALTALNLNMLDAPVSGGAVKAAQGEM.............................................. 134
28 -10.100d2gf2a1 c.2.1.0 (A:41-201) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  15  2.....................................................................................................................................................VGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDASPADVAEKADRIITMLPTSINAIEAYSGANLKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNL.............................................. 131
29 -10.100d2uyya1 c.2.1.0 (A:262-429) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  12  5.................................................................................................................................................TDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQETPAEVVSTCDITFACVSDPKAAKDLVLGPSLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLV............................................. 139
30 -9.990d2i76a2 c.2.1.6 (A:2-154) Hypothetical protein TM1727 {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  14  1....................................................................................................................................................VLNFVGTGTLTRFFLECLKDRYEIGYILSRSIDRAYGGKAATLEKHPELNGVVFVIVP-----DRYIKTVANHLNLGDAVLVHCS--GFLSSEIFKKS....................................................................... 97
31 -9.970d1c1da1 c.2.1.7 (A:149-349) Phenylalanine dehydrogenase {Rhodococcus sp., M4 [TaxId: 1831]}  ali model 3D-neighbors follow..  20  24...............................................................................................................................................SLDGLTVLVQGLGAVGGSLASLAAEAGAQLLVAD-AHAVALGHTAVALEDVLSPCDVF---APCA--MGGVITTEVARTLD-CSVVAGAANNVIADEAASDILHARGILAGGAIHLVGREVLGWSESVVHERAVAIGDTLNQVFEISDNDGVTPDEAARTLA............ 193
32 -9.960d3vpxa2 c.2.1.0 (A:145-363) automated matches {Sporosarcina psychrophila [TaxId: 1476]}  ali model 3D-neighbors follow..  16  26...............................................................................................................................................SLAGKTVAVQGVGNVAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGATAVGINEIYSQEADI--ALGAIINDETIPQLK-AKVIAGSANNQLKETRHGDLIHEMGIVNSGGVINVADELDGYNRERALKRVEGIYDVIGKIFAISKRDNIPTYVAADRMA............ 195
33 -9.890d3ws7a1 c.2.1.0 (A:1-161) automated matches {Pyrobaculum calidifontis [TaxId: 410359]}  ali model 3D-neighbors follow..  13  2....................................................................................................................................................RVGFIGLGIMGGPMATHLLKAGFLAAVYNRTREKTKPFAEASPADLAKRVDVVIVMVSDAPDVEQVLFGPSVEGARPGLIVVDMSTNSPDWARKFAERLAQYGIEFLDAPVTGGQKGAIEGTL.............................................. 132
34 -9.670d1i36a2 c.2.1.6 (A:1-152) Conserved hypothetical protein MTH1747 {Methanobacterium thermoautotrophicum [TaxId: 145262]}  ali model 3D-neighbors follow..  18  2....................................................................................................................................................RVGFIGFGEVAQTLASRLRSRGVEVVTSLEGRSPSTIERARTSEEDVYSCPVVISAVTPGVALG-YVDINNISPETVRMASSLIEKGGFVDAAIMAEEFMKLNRYGLNIEVRGREP..................................................... 152
35 -9.230d3fr7a1 c.2.1.0 (A:86-307) automated matches {Oryza sativa [TaxId: 39947]}  ali model 3D-neighbors follow..  17  38................................................................................................................................................KGIKQIGVIGWGSQGPAQAQNLRDSLAEAKSDIVVKIGEESGTLGDIWETVSGSDLVLLLISDAAQAD--NYEKIFSHMKPNSILGLSH.................................................................................... 141
36 -9.160d1j5pa4 c.2.1.3 (A:1-108,A:220-241) Hypothetical protein TM1643 {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  14  2....................................................................................................................................................TVLIIGMGNIGKKLVELGNF----IYAYDRISKDIPGVVRLDEFQVPSDVSTVVECAS-----PEAVKEYSLQILKNPVNYIIISTSAFADEVFRERFFSELKNSPARVFF.......................................................... 105
37 -9.030d2f1ka2 c.2.1.6 (A:1-165) Prephenate dehydrogenase TyrA {Synechocystis sp. PCC 6803 [TaxId: 1148]}  ali model 3D-neighbors follow..  17  2....................................................................................................................................................KIGVVGLGLIGASLAGDLRRRGHYLIGVSRQQSTCEKAVERQL-SLLQTAKIIFLCTPIQLILPTL--EKLIPHLSPTAIVTDVAKTAIAEP---ASQLWSGFIGGHPMAGTAAQGIDGAEENLFVN-APYVLTP.................................. 139
38 -9.020d2dapa1 c.2.1.3 (A:1-118,A:269-320) Diaminopimelic acid dehydrogenase (DAPDH) {Corynebacterium glutamicum [TaxId: 1718]}  ali model 3D-neighbors follow..  17  1................................................................................................................................................MTNIRVAIVGYGNLGRSVEKLIAKQDMDLVGIFSRRATLDTFDVADVDKHADDVDVLFLCMGFAQFACTVDTYDNHRDIPRHRQVMNEAATAIAFGRAAHRMKQQGQSGAFTV............................................................ 150
FFAS is supported by the NIH grant R01-GM087218-01
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Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Schwarzenbacher R, Godzik A, Jaroszewski L. The JCSG MR pipeline: optimized alignments, multiple models and parallel searches. Acta Crystallogr D Biol Crystallogr. 2008 Jan;64(Pt 1):133-40. Epub 2007 Dec 5.