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Query: 5NQJ Entity 1(prereleased), from PDB1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRFLPCIATLAATASALAIGDHVRSDDQYVLELAPGQTKVVTEAEKWALRAEGKRFFDITERASSLELASNKKQKLAVTYPDSVQHNETVQNLIKSLDKKNFETVLQPFSEFHNRYYKSDNGKKSSEWLQGKIQEIISASGAKGVTVEPFKHSFPQSSLIAKIPGKSDKTIVLGAHQDSINLDSPSEGRAPGADDDGSGVVTILEAFRVLLTDEKVAAGEAPNTVEFHFYAGEEGGLLGSQDIFEQYSQKSRDVKAMLQQDMTGYTKGTTDAGKPESIGIITDNVDENLTKFLKVIVDAYCTIPTVDSKCGYGCSDHASATKYGYPAAFAFESAFGDDSPYIHSADDTIETVNFDHVLQHGRLTLGFAYELAFADSLLast
1 -62.800[R] COG2234 Predicted aminopeptidases  ali follow..  13  19........................................................................................ILPAQAASPGPGEIANTQARHIAFPGRMTGSPAEMLSADYLRQQFTQMGYQSDIRTFNSRFIWHNVTGSTVIAAHEGRVPQQIIIMAHLDTYAPQSDADLTLQGMDDNAAGLGVMLELAARLKDI------PTHYGIRFIATSGEEEGKLGAENLLKRMSDEKKNTLLVINLDNLIVGDKLYFNSGKNTPEAVRTLTRDRALAIARRYANTNPGRNPSYPKGTGCCNDAEVFDKAGISVLSVEATNWNNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIMLPL... 337
2 -59.400[O] KOG3946 Glutaminyl cyclase  ali follow..  13  26.....................................................................TSQKDNLVGRTQISYNPSELSEPRFLEYSNLSDKLHLREAIDLIPRVVGTTNHSIVREYIVQSLRDLDWDVEVNSFHDHPIKGKLHFHNIIATLNPNAERYLVLSCHYDSKYM---PGVEFLGATDSAVPCAMLLNLAQVL-QEQLKPLKKSKLSLMLLFFDGEEAFIYGARHLAKKWHHEGDRIDMLVLLDLLGAPDPAFYSFFENT-RLAKLQLLERYASSGVAQRDPTRYFQSQAMRSSFIEDDHIPFLRRNVPILHLIP---VPFPSVWHTPDDNASVIDYATTDNLALIIRLFALEYLLAGT. 349
3 -46.000[R] COG4310 Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain  ali follow..  15  103..........................................................................................IPQRRVMPLGELQAHIHTLPAYKTAYYTDAWGFCMAHHDFLKLEEGDYE-----VVIDTEKTSGNLFYGEYLHRGKNAKEVLLFAHICHPS----------LANDNCSGLALLTCLAAGLKSR------STYYSYRFVFAP----GTIGSLSWLARNEEGISNIAHGLVVSCIGDGGGPN---------KRSRRGDALIDRIAACTRCGEDRKHLEIADFIPYGYDERQFCSPGFPVGLLQRSAFGT-FPEYHTSADNLDFIRPEHLASSFWMIMDMIDALEDNWT. 362
4 -44.500[R] COG4882 Predicted aminopeptidase, Iap family  ali follow..  14  1.....................................................................................................MAEVFKKCVAYKDLIAGGPGEREFLQWLIAFLDAPRVWFHLSRLIIDVKSRVTYSYSLIAFNSF--ENTPMISAHWDHW---------LAGATDNCAGLEAAILAFTELVA--------DDTPIALGLFTAEEGVGPHVPSFYSLNYFKRWKPTPLVNIDVVGVGTPR--------------YAMPYLHEFLKGLGPV---------ESPEAYFDSVHYERWGLPSVTISSL--RDTWSFYHSPSDTHAEME--NILYVADLAKRLAKIKPPQPAV 354
5 -31.900[OR] KOG2194 Aminopeptidases of the M20 family  ali follow..  14  53..............................................................................................PQFSEANALKHVIHLSDIGYRILGTIEQERAREYIMNEVLALQKQLQDGPMNKYVIKKYQNLKNIVVRLSNGTEEAVLINAHVDST-------LPSPGATDDALAVAILLEAIRIFISRPV----PLTHSIVFLFNDAEESLQDASHMFITQSP--RDTIKCVVNLEACG-------TTGSEILFQATSNEMIKAYSHVPHPFGTVLADDVFRTGLILSDTDFRQFVQYG--NLTGLDMAVVKNSYLYHTKKDLAPYISPGTPQNFGENILAILTYLVSPEAD 341
6 -27.400[OPR] KOG2195 Transferrin receptor and related proteins containing the protease-associated (PA) domain  ali follow..  18  240................................................................................................VGYYDAQKLLEKMGG-SAPPDSSWRGSLKVSYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGAPDRYVILGGHRDS----------VFGGIDPQSGAAVVHETVRSFGTLKK-EGWRPRRTILFASWDAEEFGLLGSTEWAEDNSRLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVYNLTKELKSPDEGFEGKSLYESWTKKSPSPSGNDFEVFFQRGIASGRA-ETNKFSGYPLYHSVYETYELVEFKYHLTVAQVRGGMVFELANSIVL 536
7 -17.200[E] COG4187 Arginine degradation protein (predicted deacylase)  ali follow..  13  1.............................................................................................MNWQTKDELLALLTSLVQYES--TGSKGEVALAEYLYFILKDKPYFQ-KHPDDVTPHPMDDGRSFLTALVKKKVKKTVLLLSHFDVVDIEDYGEFKHMGTMDMKAGLCIQLSMLERAMNG------HFEGNLLLITVPDEEVNSRGMIEAVPALKEMEKKHDITLTACLNAEPMFEKFPGDQQQYFYTGSIGKVLAGFFCK------------------GIETHVGEPFSGLNANLMVS............................................. 249
8 -17.200[E] KOG2275 Aminoacylase ACY1 and related metalloexopeptidases  ali follow..  14  5...............................................................................................KWENNEEIKIFREYLRIPT--HPDVDYTACVEFLKRQASSLNLPVEVVYPAVQ------TKPVVIIKWEGSQPELIVLNSHTDVVPVFREKWTHEPGTQDMKSVGTQYLGAIRLLKA----SGFKPKRNLYVTFVPDEETG-LGMAEFVKTDYYKKMNARWGLKLKVSGTSGHGSLLLPNTAGVKLNVAFEKQIRDWCEEAGGGIEIDFFQKEPY--GATDSRFIREKGTPAIGF--SPIINTTMRIHDHDE---FLQADVYLNGIDVYKKIIRNLAE.... 400
9 -16.500[E] COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases  ali follow..  12  1................................................................................................MTETQSLELAKALISRPS----TPDDRDCQKLLVERLYKIGFAAEELHFG--------DTKNIWLRR-GTKVPVVCFAGHTDVVPTGPVEKWDSPGAADMKTSIACFVTACERFVA----EHPDHQGSIALLITSDEEGDLDGTTKVVDVLKARGELIDYCINLTVKGKQGHIAYPGGTGATNVIPGELAGKLTDVARAAIAETCGIEAELSTTG-GTSDGRFIKAIAKELI-----ELGPSNATIHQINE---NVRLDDIPKLSAVYEGILARLLAGNAV 381
10 -14.000[O] KOG3566 Glycosylphosphatidylinositol anchor attachment protein GAA1  ali follow..  10  59..........................................................................AKNTYISENALMPGSARSMLSNRDVSDGSKLVKDIKNFR-----LNHEGQVQKLIGKYMSDMGAEVSYQKFHPEGVSCASYGVNVAGIIRGDGKESIVLVTPYDF----------INGGDYEDLSLGIVSSLFSLLSRVTWLS-----KDIIWLVADSRYGDYRPVAAWLTEYHSPSFKMAAALVLKVDGRSEKFEDTLSIYAEASNGQMPNLDLINVVNYLAVHRQGFYVKVEKVGIPTGPHGAFRDYQVDAITL-----------SPRFPPDSKTRQHDFFLRGARLLEGTIRSVNNLLE. 430
11 -13.900[G] COG1363 Cellulase M and related proteins  ali follow..  20  1.....................................................................................................MKSLLEVFTNAHG----SGSEDEVRKLLEQELKPYVDSMRKDTM------------NLIAIKEGKGPS-VMLAAHMDEIGLDAENLGIEIGAFDNRAGVVILLEVMKRLHER------KIEANVYAVGTVQEEVGLKGAKTCAFGLC---PDVALALDTTIPGDHPGISKTDSALELGGRGLIAHPQVLKWLRETADAN-EIPYQLGVGSGGTTDATSIHKEGIPTGTV----------YIHSPVEVLDMADIEAC---VSLIVKSIENVKT.... 346
12 -13.400[E] COG2195 Di- and tripeptidases  ali follow..  16  2...........................................................................................SELSQLSPQPLWDIFAKICSIPH---PSYHEEQLAEYIVGWAKEKGFHVERDQVG-----------NILIRKPATAGKPVVLQAHLDMVPQKNNARGTTLGA-DNGIGMASALAVLA--------DENVVHGPLEVLLTMTEEAGMDGAFGLQSNWLQADI----LINTD.................................................................................................................... 169
13 -11.100[E] KOG2276 Metalloexopeptidases  ali follow..  11  2......................................................................................TVDLTNVFQQIDGELLREAVA-IQSVSGDPSKRDETIRMVHWMKEKLETIGTICELADLGTQELEGKTVKLPLLGTLGSDKNKTLLVYGHLDVQPAAKSDGWDTEGSSDDKGPVLCWFHAIRAAQK----NGIDLPVNIKFCLEGMEE---SGSVGLPELLEREKDRFLA--GVDFVCISDSYWLGTKKPCLTYGLRGICSFFVEVTGIKQDLHSGVFGGVIHEPLQDLMWVMSQLTTVDNRIKIPGLYEQVAPLSAAEEKTYDDIEFDVAEFRDSVGASKLPTEDKKTLL 305

FFAS is supported by the NIH grant R01-GM087218-01
1 4 5 9 0 4   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Functional differentiation of proteins: implications for structural genomics. Structure. 2007 Apr;15(4):405-15.