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Query: 5YM9 Entity 1(prereleased), from PDB1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst KLESPGFMVHKKLKSMSQSYGVMMTGVPAEVLGQMQAERSIPSINKTGNLKQQIAKEVSKVCHMMTEPTQSCGQASNDVCELLLGKIEAEKFHFTKYEALSADGDNLKNVLENTAPSSTNLLIRFEIDREDPPIVLVKTKNENFNPETAVKNKIYLLENKLYFIDKMGNLFNLGPGKKKCTQLFNAIGDSAEYSLCDPFVLEEPEKPEDFAISEIVDIFNEQKERFDFWIGSHSFTIYIPQTLGESPRQFYPYQAYFGSHTLQDWFVSDKDEYLSRIGIDKYIEKLAVLGKTTNTKERSDIYAEFFSKRGREAFFCAHLNEKRQPLRVKFKITEINPELALKNLQETQEFIDTHPGENPSDKVENYRNRAKLAMTEHLESLLDILast
1 -4.650[S] COG3101 Uncharacterized protein conserved in bacteria  ali follow..  14  7...................................................................................................................................................................................................................YEQLIEIFNSADDFNTRLIKGDDEPIYLPADAEVPYNRIVFAHGFYASHEISHWCIAGKA------------------------RREQVDFGYWYCPDGRDA-----------QTQSQFEDVEVKPQALDWLFCVAAGYPFNVSCDNLEGDFEPDRVVFQRRVHAQVMDYLT. 147
2 -4.290[S] COG4004 Uncharacterized protein conserved in archaea  ali follow..  13  14.................................................................................................................................................................................................................................................................SEQTLSEMKISYWQQYKLKRGFKPEPDRIYQVMQECFPVEISRNGDRFETSYGAMSKITVWVENKKLCVDTVSDVTVKDDETILQTNKAYRDFLLMATGYTAKERLKMAKKEVGEA........... 133
3 -4.170[J] KOG3409 Exosomal 3`-5` exoribonuclease complex, subunit ski4 (Csl4)  ali follow..  10  9VVCLPGERLCRTEDSIVLGIGTYEQNIYASKSGIVNIEDSGDKCQVVSVHKPGFHLTIPAT-------------------DVVTARVLVTTPKFAKCAIFCVRNVLLESSYRGL----------LRKEDVRETEKDRVDIYKSFRPGDVILARVINQLEQSFLLTTAEN--ELGVVIAYASDY......................................................................................................................................................................................................... 163
4 -4.060[O] KOG2813 Predicted molecular chaperone, contains DnaJ domain  ali follow..  11  205.................................TGRGDVVCPTCNADGEPGFYKENQMMKCSTCYGRGLVAHKDGSDTICTNCNGK-------KLPCPTCQSRGLIKCQTCDSTGSLLTSSIAVVKWKTLSKRKVSATRGAGSVPEEVFDRAE----GVQLCNTQAYQCTPAYFADSYFLNRFSSEVISLRAEVPPTANVVCERHTISVVPVTRV---MEDRGKAFSFYIIGFGKEIYLKD--------YYPARFCWGLCPCLEWL...................................................................................................................... 417
5 -3.890[R] COG2372 Uncharacterized protein, homolog of Cu resistance protein CopC  ali follow..  18  23.LSSQQALAHAHLKAETPAADTTINAAPEALT-SEGIELNFSGVKVTGPDNNVVKTGDLKL-----------DPANNTQLILPIGHALAAGKYHVSWHVVSVDGHKTKGTYS................................................................................................................................................................................................................................................................................ 124
6 -3.840[V] KOG2392 Serpin  ali follow..  11  34..............SISSAMAMVFLGTRGNTAAQLSKTFHFNTVEEVHSRFQSLNADINKR-YILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHASEDARKTINQWVKGQTEGKIP-----------------ELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLEL-----------PYQGEELSMVILLPDDIEDESTGLKKIEEQLTLEKLHEWTKPENNVSLPRFKLEESYTLNSDLARLGVQDLFNSSKADLSGMSGARDIFISKIVHK-----SFVEVNEEGTEAAFCMLMPEENFTADHP............................. 357
7 -3.800[J] KOG3070 Predicted RNA-binding protein containing PIN domain and invovled in translation or RNA processing  ali follow..  20  321.............................................................................................................................................................................................FCDGSIEHKWISEEDGEDTSRALSPL----------------SHPYSL--------GPR-YHPFHTHSSPHR------EGRDQCVG-IKVNIYLEQHALL--CSPAKREARLGNATYPSTSKSQCDC---------LPMKRKLSEACVEPALKQSRKTEEYPIRYPSQGTKAM...................... 465
8 -3.750[J] COG1096 Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain)  ali follow..  10  15DFVLPGDYL--VIEEYLPGEGVIVEDLYSARAGWVKINKDKVEISLEPASSVPPIPKKG---------------------DIVYARVIDVKQQAVLLRMIKIEGQENREIATSKL----------GIHISQVKDGFVEDLRNEFKIGDIVRARVIADEKSPIQLTTKDP--DLGVVYALCSKCRTPLVRKGNQLVCPRCGNVETRK.................................................................................................................................................................................. 189
9 -3.750[S] COG3369 Uncharacterized conserved protein  ali follow..  11  8..........KEMRIKIVKDGPYRVTGGVPLLEQVIVTDDAGHTRELIDIKEYPRRESYILCR--------CGSSENKFCD---GTHSKIGFDGSETASRKPYMEKAETVEGPDLKLTDA--SRFCQRSGGIRDLIQKSDDPEARQTQKNCEGPLWVRGGIPIESADGSMYESRNRVTLC-----RCGKSENKPYCDGSHWMNSQQKLEFRKKWGLE....................................................................................................................................................................... 241
10 -3.700[S] COG4871 Uncharacterized protein conserved in archaea  ali follow..  16  69......TQKGEIITTIYGTGKVTMTMIKNEDEAREALENLRDIINEAIAKGVAPVPREKVRVEPME-PQTNCGKCGEQSCKLMSGETNLEKCMPLKEPGYATNLEHLQVLSA................................................................................................................................................................................................................................................................................ 183
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zmasek CM, Zhang Q, Ye Y, Godzik A. Surprising complexity of the ancestral apoptosis network. Genome Biol. 2007 Oct 24;8(10):R226 [Epub ahead of print]