current user: public
If you have questions about the server, please let us know.

Query: 5YTA Entity 1(prereleased), from PDB1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330
# Score Template Links and tools%idFirst ATLKEKLIAPVAEEETTIPNNKITVVGVGQVGMACAISILGKSLTDELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGVHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVQGMYGIENEVFLSLPCVLNARGLTSVINQKLKDDEVAQLKNSADTLWGIQKDLKDLast
1 -94.800[C] KOG1495 Lactate dehydrogenase  ali follow..  62  2AAIKDSLLAQVA-EVLPSSGHKVTIVGIGQVGMASAFSILAQNVSKEVCLIDVCADKLQGELMDLQHGSNFLKNPQITASTDFAASANSRLCIVTAGVRQKEGESRLSLVQRNTDILKNIIPKLVEYSPDTILLMVSNPVDIMTYVAWKLSGLPKNRVIGSGTNLDSSRFRFLMSQRLGVAPTSCHGWIIGEHGDSSVPVWSGVNIAGVRLRELNPILGTGEDPEKWNELHKQVVDSAYEVIKLKGYTSWAIGLSTASLASAILRNTSSVAAVSTSVLGEHGIDKDVFLSLPCVLNANGVTSVVKQILTPTEVEQLQKSANIMSDVQAGLK. 331
2 -88.000[C] COG0039 Malate/lactate dehydrogenases  ali follow..  36  2...............NKFKGNKVVLIGNGAVGSSYAFSLVNQSIVDELVIIDLDTEKVRGDVMDLKHATPYSPTTVRVKAGEYSDCHDADLVVICAGAAQKPGETRLDLVSKNLKIFKSIVGEVMASKFDGIFLVATNPVDILAYATWKFSGLPKERVIGSGTILDSARFRLLLSEAFDVAPRSVDAQIIGEHGDTELPVWSHANIAGQPLKTLLEQ--RPEGKAQIEQIFVQTRDAAYDIIQAKGATYYGVAMGLARITEAIFRNEDAVLTVSALLEGEYDEE-DVYIGVPAVINRNGIRNVVEIPLNDEEQSKFAHSAKTLKDIMAEAEE 315
3 -71.200[C] KOG1494 NAD-dependent malate dehydrogenase  ali follow..  20  10SASAKQAVIRRSFSSGSVPERKVAILGAGGIGQPLALLMKLNPLVSSLSLYDIAN--TPGVAADVGHINTRSEVVGYMDDNLAKALEGADLVIIPAGVPRKPGMTRDDLFNINAGIVKNLCTAIAKYCPHALINMISNPVNSTVPIAFKKAGMYDEKKLFGVTTLDVVRARTFYAGKANVPVAEVNVPVIGHAGVTILPLFSQVSSHFLSTQTVATP-QANLSSDILTALTKRTQDGGTEVVEGKGSATLSMAYAGALFADACLKGLNGVPDVIECSYVQSTITELPFFASKVRLGKNGVEEVLDLPLSDFEKEGLEALKPELKSSIEKGVK 348
4 -18.200[G] COG1486 Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases  ali follow..  14  2.................KKGVKIVTIGGGSSYTPELVEGFIKRYIRELWLVDIEAGREKLEIVKRMVKAANIDCEVHLTLDRREALKDADFVTTQFRVGLLDARIKDERIPRTIPVILGIVEDMRELCPDAWLINFTNPAGMVTEAVLRYG--NWDKVIGL----VPIGAVKSASDVLEKPEEDLFFKFAGNH----LHWHRVFDKDGTELEKVIDGLYAPDANPGKVVENIKNMRFLYEQVKHLKMLPCP-SDAACEIINSIYNNKGTVMVVSTRNNGAIDVPYDSAVEITSVIRAHGAEPINFGKFPPAQRGLLQVMKSMEELTIEAAVT 398
5 -8.900[I] KOG2304 3-hydroxyacyl-CoA dehydrogenase  ali follow..  9  3SSTCTAAVRGLSTTAQLSKINNVTIIGAGLMGSGIAQVSANAKL--NVTVVDSNQSALEKAQQGIANSLKRVAKKKHADDAA-DSVKDADLVI--------------EAIVENIDIKRKLFAEVEVAAKPTTLI-TTNTSSLRLADIGLNLKDKSR--------------------------------FGGLHFFNPVPMMKLLEV-----------RHTETSDATFNQLVDYGKTVGKTTVACKDTP----GFIVNRLLVPYMFEALRLYERGDASMEDIDVAMKLGAGYPMYVGLDTCKFIMDGWHAQYPEEVAFTPSPLLNSLVDS... 294
6 -8.860[R] COG1712 Predicted dinucleotide-utilizing enzyme  ali follow..  23  3.....................KIGIVGCGFIGGQICRAIDGGEVSAELYLCDSSESKALELAASLKTCKPSYMKIEEL-------IRGVDLIIESASQ----------------NAVRFIVPQALKAGCD---VMILSVGALAD............................................................................................................................................................................................ 100
7 -8.820[Q] COG4569 Acetaldehyde dehydrogenase (acetylating)  ali follow..  14  1.................MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVIGLMNM-PEFADIDIVFDATSAGAHVKNDAA-LREAKPDIR------LIDLTPAAIGPYCVPVVNLEANVDQLNVNMVT-------GGQATIPMVAAVSRVARVHYAEIIASIAGP............................................................................................................................................ 165
8 -8.700[I] COG1250 3-hydroxyacyl-CoA dehydrogenase  ali follow..  13  3....................KTVGIIGAGQMGCGIAHVSAAAGY--KVQLYDIAADRIEAGLATINGNLARQVSSGKMSSGDINDLAQADLVI--------------EAVTEDETVKRKIYGQVCPVMRPDAIL-ATNTSSLSITRLASATDRPER--------------------------------FMGIHFMNPVPVMKLVEL-----------RGIATEEETFKAAKEFVAHLDKTVTVAEDFP----AFIVNRILLPMINEAIYTLYEGVGTVDAIDTAMKLGANHPMLADFIGLDTCLSIVLHDGLADSKYRPCPLLVKYVEA... 267
9 -8.250[R] COG2085 Predicted dinucleotide-binding enzymes  ali follow..  10  2................SHTKPSIAILGAGRVGSSLARSAVAAG--YEVKVAGSGAVDKIALTAEILMPGAVPSTAD-------QAVKDADIVFLAV--------------------LHKFRSVNPATLEGKIVIDTMNHWVPVNGELEEIDQFAGSTMVKSFNHIGYHEIEQDAGTGRAI-------AYATDDVDAGAQVAQLIKSFG............................................................................................................................ 170
10 -7.770[E] COG0287 Prephenate dehydrogenase  ali follow..  13  3...............GDIMFERIALIGIGLIGSSIARDVRELGLARHVVISTRSEDTLK--------------------------------------------------RAEELALGTDYTVSAAEAVKDADLVIVSVPVGASESVAQQIAPYLKPSAI----VTDVGSTKASVIAQMAPHMPE-NVHFIPGH------PLAGTEKSGPDAGFAGLFRERWCIFTPLPGTDAAALERLKDFWRALGSRVDEMDAEHHDKVLAIVSHLPHI--IAYNIVGTADDLETVTESEVIKYSASGFRDFTRLAASDHNKDAILEMLARFSEDLASLQR 265
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 9 1 2   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ginalski K, Grishin NV, Godzik A., Rychlewski L. Practical lessons from protein structure prediction. Nucleic Acids Res. 2005 Apr 1;33(6):1874-91.