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Query: 5Z0M Entity 1(prereleased), from PDB1018

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTVRKNQATLTADEKRRFVAAVLELKRSGRYDEFVRTHNEFIMSDTDSGERTGHRSPSFLPWFRRFLLDFEQALQSVDSSVTLPYWDWSADRTVRASLWAPDFLGGTGRSTDGRVMDGPFAASTGNWPINVRVDSRTYLRRSLGGSVAELPTRAEVESVLAISAYDLPPYNSASEGFRNHLEGWRGVNLHNRVHVWVGGQMATGVSPNDPVFWLHHAYVDKLWAEWQRRHPDSAYVPTGGTPDVVDLNETMKPWNTVRPADLLDHTAYYTFDALELast
1 -7.020[S] COG5619 Uncharacterized conserved protein  ali follow..  10  1.........MNHLALTSYLGTLAEVGFVNEFRQVVPTRTTNITTIEVGDTSKISGDETGADIAEGSTIHYLACLRQAKYSCIL------FDGSLVQLKYSTC---------EGRITNHRYLYFPCPAKLDLRSTADETIYDIVDDACLAGALDAPRLGFMRFD------FEPPKRE-----QDRRPPGEHPDAHIHIGIGLVSPISVDEFFSFLLKFYYAEFWDHQVHGQSRFREPRT..................................... 208
2 -5.580[O] COG5549 Predicted Zn-dependent protease  ali follow..  12  1..MNKKIKSLPAIANNGSKQALPELQIHPDLGISLENRSLLGDDGTDYFSQVQPSPLGYLLWSKFPVTTWQQAIKT-----AIADWQEFFPLTI--------------------VENTTEADITIFYREPPLPRIVDPETGLVSFGRARTAQANYEFYWTDTSPPQLRHRMAIAIKPGLAPLSLQGTARHELGHAL--GIWGHSDHKEDALYPAQTADVPAI-----------------------------------SPRDLRTLYRLYQQPT.. 251
3 -5.390[L] COG3695 Predicted methylated DNA-protein cysteine methyltransferase  ali follow..  16  18...AEKLSEEKMEKEDSFPQRVWQIVAATTYGDVAKLAGSPRAARQVGGVLKRLPEGSTLPWHRVVALLAEGVMVSGSGQIDLQRYRWN.......................................................................................................................................................................................... 128
4 -5.340[C] KOG0768 Mitochondrial carrier protein PET8  ali follow..  10  138IKTKLQ----TKGASQVYSNTFDAIVKTFQAKGILGFYSGVSAVIVGS-----------TFSSAVYFGTCEFGKSLLS------------KFPDFPTVLIPPTAGAMGNIISSAIMV-PKELITQRMQAGASGRSYQVLLKILEKDGILGLYAGYSATLLRNLPAGVLSY-SSFEYLKAAVLEKTKQSHLEPLQSVCCGALAGAISATTP--------LDVVKTRLMTQIHVEAVDKLGGAMYTGVAGTVKQILTEEGWVGFTSAIGYFAFETAR 390
5 -5.280[I] KOG3729 Mitochondrial glycerol-3-phosphate acyltransferase GPAT  ali follow..  13  200.RAISILKDMGSTLNNGLLAFTSWILYPCFLSG-VVTNTKQIEMLKTATERSPGTPLIFVPLHRSHLDYIMVTWILTNNDIRSPL-----------------------------VAAG----------NNLQIPVFGGLLRGLGA-------------------------------------------------FFIKRKIDPVEGKKDVLY-ALHLYLTHALKQGHNVEGGRTRTGKPCMPKGGILSVIVNAFMDGSIPDALLVPVSVNYERL. 391
6 -5.180[S] COG5426 Uncharacterized membrane protein  ali follow..  1..MKILFIGESWHIHMIHSKGFDSFTSSKYEEGADYLLSCLRQGNIDVDYMPAHIVQTRFPQTAEALACYDAIVISDIGSNTFLLQNRTFYNMDIIPDALQLIADYVAEGGGLLMIGGYLSFTGIE---AKANYKNTVLAEVLPVDMLDVDDRVELPQGCKAVNTAVEHVITQPFSEWPPLLGYNKLIAKE-------NSQVLAEINGDPLLVMGT-ASDCSP-HWGSPQ............................................. 225
7 -5.120[I] COG2937 Glycerol-3-phosphate O-acyltransferase  ali follow..  12  247.NAIALMEEIAANFSYEMIRLTDRILGNRLYQGINVHNAERVRQLAHDGHEIV-----YVPCHRSHMDYLLLSYVLYHQGLVPPH-----------------------------IAAGINLNFWP-AGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYS--------------------------VEYFVEGGRSRTGRLLDPKTGT--------------------------------LSMTIQAMLRGGTRPITLVPIYIGYEHV. 429
8 -5.050[I] KOG3730 Acyl-CoA:dihydroxyactetone-phosphate acyltransferase DHAPAT  ali follow..  12  88.EAEEILDEMSHTFNLYNVRSFGYAVCEKLYDGIYVNEKKLLEIRERSKKDCV----IFMPSHKTYFDFLLLSLICFQYDIQLPA-----------------------------IAAGQDFMSMKFMAGVLRRSGAFFMRRSFGTDQ-WAVFSEYVQTHVVNNDRT--------------------------VEFFVEATRSRVGKSLHPKYGM--------------------------------LQMVLEPYLRGSVYDIVIVPVSMNYDKI. 273
9 -5.020[C] KOG0758 Mitochondrial carnitine-acylcarnitine carrier protein  ali follow..  39IKVRLQTMP-APGEQPLYRGTFDCAAKTIKNEGVRGLYKGMSAPLTGV-----------APIFAMCFAGYALGKRLQQ------------RGEDAKLTYPQIFVAGSFSGLFSTLIMAPGERIKVLLQTQQGQGGEDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLYF-LVYEALQDVAKSKSETGQISTASTIFAGGVAGMAY---P--------ADVLKSRLQSAPEGTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLNAACFFGIELAN 296
10 -4.950[C] KOG2451 Aldehyde dehydrogenase  ali follow..  10  75....LSYRNSDIKERYAILRRWYDLIMENA-DDLATMMTLENGKALGDAKGEVVYAAKFIDWFAGEALRISGDSQPVGVVGIITPWNF--------PAAMITRKVGAALAAGCTVVIRPAAETPFTALALAKLAERAGVPAGVLNMVTANSPSEHGIELTTNPLIRKVSFTGSTNVGKILAKQSSSTLKKLSLE--LGG--------NAPFIVFEDADLEKA..................................................... 287

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Functional differentiation of proteins: implications for structural genomics. Structure. 2007 Apr;15(4):405-15.