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Query: 1pq3_A mol:protein length:306 Arginase II, mitochondrial precursor, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst HSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSSLGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPGFSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIGKRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLATSEEEAKTTANLAVDVIASSFGQTREGLast
1 -99.3001pq3_A mol:protein length:306 Arginase II, mitochondrial precursor  ali model  100  1HSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSSLGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPGFSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIGKRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLATSEEEAKTTANLAVDVIASSFGQTREG 306
2 -94.3001wva_A mol:protein length:322 Arginase 1  ali model follow..  60  6RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADI-PNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREG 310
3 -94.2001d3v_A mol:protein length:323 PROTEIN (ARGINASE)  ali model follow..  61  6KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPF-QIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCFGTKREG 310
4 -94.0001t5f_A mol:protein length:314 Arginase 1  ali model follow..  60  1KPIEIIGAPFSKGCPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPF-QIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARVHPDLAVIWVDAHTDINTPLTTSSGNLAGQPVAFLLKELKGKFPDVPGFSWVTPAISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLGRKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSAFGTKREG 305
5 -86.9005ynl_A mol:protein length:362 Arginase  ali model follow..  45  50RTAGIVGCPFSGGQPKAGVHSGPLQLIESGLLNDIENLGWTVDFAGADALAVSIVSDTPDGRLKQPRLVSRVTKDVADRVYAHASKGQLTVTLGGDHSLAMGTVSGTFKAYPEACLIWVDAHADINTPHTTESGRLHGCPVSFLLGLDGTSSEEIPEFSWIKPCLKPERIVYIGLRDIDAGERKILKDNNIKCFSMFHVDKYGIGKVVEMALDHVNPDRTRPIHLSFDVDALDPSVAPSTGTAVRGGLTFREGHYICEAIAETNLLVSLDIMEINPSLGALASVA-QTVDVGRSLVRCALGETL.. 355
6 -86.7002eiv_A mol:protein length:291 Arginase  ali model follow..  36  2ERVAVVGVPMDLGANRRGVDMGPSALRYARLLEQLEDLGYTVEDLGDVPVSLARASRRRGRGLAYLEEI-RAAALVLKERLAALPEGVFPIVLGGDHSLSMGSVAGAAR-GRRVGVVWVDAHADFNTPETSPSGNVHGMPLAVLSGLGHPRLTEV------FRAVDPKDVVLVGVRSLDPGEKRLLKEAGVRVYTMHEVDRLGVARIAEEVLKHL---QGLPLHVSLDADVLDPTLAPGVGTPVPGGLTYREAHLLMEILAESGRVQSLDLVEVNPILDERNRTAEMLVGLALSLLGKRI...... 290
7 -84.7001cev_A mol:protein length:299 PROTEIN (ARGINASE)  ali model follow..  37  2KPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERLHYDIEDLGDIPIGKAERLHEQGDSLRNLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKHYERLGVIWYDAHGDVNTAETSPSGNIHGMPLAASLGFGH---PALTQIGGYSPKIKPEHVVLIGVRSLDEGEKKFIREKGIKIYTMHEVDRLGMTRVMEETIAYL-KERTDGVHLSLDLDGLDPSDAPGVGTPVIGGLTYRESHLAMEMLAEAQIITSAEFVEVNPILDERNKTASVAVALMGSLFGEKL...... 298
8 -84.5006dkt_A mol:protein length:296 Arginase  ali model follow..  38  3KTISVIGMPMDLGQARRGVDMGPSAIRYAHLIERLSDMGYTVEDLGDIPINR--EKIKNDEELKNLNSVLAGNEKLAQKVNKVIEEKKFPLVLGGDHSIAIGTLAGTAKHYDNLGVIWYDAHGDLNTLETSPSGNIHGMPLAVSLGIGH---ESLVNLEGYAPKIKPENVVIIGARSLDEGERKYIKESGMKVYTMHEIDRLGMTKVIEETLDYL--SACDGVHLSLDLDGLDPNDAPGVGTPVVGGISYRESHLAMEMLYDAGIITSAEFVEVNPILDHKNKTGKTAVELVESLLGKKL...... 295
9 -82.2004ity_A mol:protein length:330 Arginase  ali model follow..  37  8KKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVFDGKVVEARKDRIGRVKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGTVAGVLSVHPDAGVIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPEC--FSWVPQVLKPNKIAYIGLRAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVSPKGTEPVMVSYDVDTIDPLYVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLAATESHVNDTISVGCAIARCMMGETLLY 316
10 -80.4004q3p_A mol:protein length:385 Arginase  ali model follow..  41  37TSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQRFLRIAERVEELMKQSNKHTVELSGSKSTPVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEDVL-KTQSSAVHILRACLGHCRSG 354
11 -77.0004g3h_A mol:protein length:330 Arginase (RocF)  ali model follow..  19  1..MILVGLEAELGASKRGTDKGVRRLREALSATHGDV----IKGMQTITQERCVLYKEFRYAKNFEDYYLFCKENLIPCMKEVFEKKEFPLILSSEHANMFGIFQAFRSVHKKIGILYLDAHADIHTAYDSDSKHIHGMPLGMVLNRVRSGFNRMSGLEKGGLEIDPKCLVYFGVRSTEQSERDVIRELQIPLFSVDAIRE-NMQEVVQKTKESL--KAVDIIYLSLDLDIMDGKLFTSTGVRENNGLSFDELKQLLGLLLESDRLKAVEVTEYNPTVSIKHNNEKQVLEILDLIINSCKIKDKKH 316
12 -73.8003nio_A mol:protein length:319 Guanidinobutyrase  ali model follow..  26  39.DAAFVGVPLDIGSLRSGTRFGPREIRAESVMIRPYNMATGAAPFDSLNVA------DIGDVAINTFNLLEAVRIIEQEYDRILGHGILPLTLGGDHTITLPILRAIKKKHGKVGLVHVDAHADVNDHMFG-EKIAHGTTFRRAVEED---------------LLDCDRVVQIGLRAQTAEDFNWSRKQGFRVVQAEECWHKSLEPLMAEVREKV---GGGPVYLSFDIDGIDPAWAPGTGTPEIGGLTTIQAMEIIRGCQGL-DLIGCDLVEVSPPYDTTGNTSLLGANLLYEMLCVLPGVVRR. 319
13 -73.4003lhl_A mol:protein length:287 Putative agmatinase  ali model follow..  21  9.NLIVFGVGFDGTSNRPGARFASSSMRKEFYGLETYSPFLDLD-------LEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSKVPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNN-SKNSHATVIKRIWD-----------------IVGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGID------TFENIVNML---NGKNIYLTIDLDVLDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNNIVGCDIVELSPDYDTTGVSTVIACKILRELCLIISDKIKEG 281
14 -73.3001gq6_A mol:protein length:313 PROCLAVAMINATE AMIDINO HYDROLASE  ali model follow..  25  31.DVVVIGAPYDGGSYRPGARFGPQAIRSESGLIHGVGIDRGPGTFDLINCV------DAGDINLTPFDMNIAIDTAQSHLSGLLKANAAFLMIGGDHSLTVAALRAVAEQHGPLAVVHLDAHSDTNPAFYG-GRYHHGTPFRHGIDEK---------------LIDPAAMVQIGIRGHKPDSLDYARGHGVRVVTADEFGELGVGGTADLIREKV---GQRPVYVSVDIDVVDPAFAPGTGTPAPGGLLSREVLALLRCVGDL-KPVGFDVMEVSPLYDHGGITSILATEIGAELLYQYARAHRT. 311
15 -72.6003nip_A mol:protein length:326 3-guanidinopropionase  ali model follow..  23  36.QVGLIGVPWDGGTNRAGARHGPREVRNLSSLMRKVHHVSRIAPYDLVRVG------DLGDAPVNPIDLLDSLRRIEGFYRQVHAAGTLPLSVGGDHLVTLPIFRALGR-ERPLGMVHFDAHSDTNDRYFGDNPYTHGTPFRRAIEEG---------------LLDPLRTVQIGIRGSSPDDDAFARECGIRVIHMEEFVELGVEATLAEARRVV---GAGPTYVSFDVDVLDPAFAPGTGTPEIGGMTSLQAQQLVRGLRGL-DLVGADVVEVSPPFDVGGATALVGATMMFELLCLLAESAAR. 316
16 -71.2003mmr_A mol:protein length:413 Arginase  ali model follow..  30  18KNVSIIGSPLAAGQPLGGVQLACDDLRKLGLHNVIDVLGWKYEDIGNIDNGDKYKNNCYYDNIRNIKEIGIFSKNLFDTMSNELRKKNFVLNIGGDHGVAFSSILSSLQMYQNLRVIWIDAHGDINIPETSPSGNYHGMTLAHTLGLFKKKVPYF-EWSENLTYLKPENTAIIGIRDIDAYEKIILKKCNINYYTIFDIEKNGIYNTICTALEKIDPNSNCPIHISLDIDSVDNVFAPGTGTVAKGGLNYREINLLMKILAETKRVVSMDLVEYNPSLDEVDKKVHGDSLPILDNATKTG...... 391
17 -71.1003m1r_A mol:protein length:322 Formimidoylglutamase  ali model follow..  20  39.GPALIGVPLSKSISHSGASFAPGTIRQALKHSSAYSAELGEHVVS-------ELLYDLGDIDIHVTDIVKSHHHIFQTMHALLSDHPVPLILGGDNSISYSTIKAIAQTKGTTAVIQFDAHHDVRNTEDG--GPTNGTPFRRLLDEE---------------IIEGQHLIQLGIREFSQAYEAYAKKHNVNIHTMDMIREKGLIPTIKEILPVV-QDKTDFIFISVDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIAQQPNVAGIEIVEVDPTLDFRDMTSRAAAHVLLHALKGMKLSPFK. 322
18 -70.5004dz4_A mol:protein length:324 Agmatinase  ali model follow..  24  48.DVVVSGVPLDLATFRSGARLGPSAVRAASVQLAELNPYP-----WGFDPFDDLAVIDYGDCWFDAHHPLSIKPAIVEHARTILQSDARMLTLGGDHYITYPLLIAHAQKYGPLSLIHFDAHCDTWADDAP-DSLNHGTMFYKAVKDG---------------LIDPKASVQVGIRTWNDDY------LGINVLDAAWVHEHGARATLERIESIV---GGRPAYLTFDIDCLDPAFAPGTGTPVAGGLSSAQALAIVRGLGGV-NLIGADVVEVAPAYDQSEITAIAAAHVACDLLCLWRQRKAGA 323
19 -70.1001wog_A mol:protein length:305 agmatinase  ali model follow..  26  30.DVAALGVPFDIAGFRPGARFAPRALREASLRSVPPFTGLDGKT-----RLQGVTFADAGDVILPSLEPQLAHDRITEAARQVRGRCRVPVFLGGDHSVSYPLLRAFAD-VPDLHVVQLDAHLDFTDTRND-TKWSNSSPFRRACEAL----------------PNLVHITTVGLRGLDPEAVAAARARGHTIIPMDDVTADLAGVLAQLP-------RGQNVYFSVDVDGFDPAVIPGTSSPEPDGLTYAQGMKILAAAAANNTVVGLDLVELAPNLDPTGRSELLMARLVMETLCEVFDHV... 304
20 -68.5003pzl_A mol:protein length:313 Agmatine ureohydrolase  ali model follow..  26  36.KYVVFGIPFDNTSYRRGSKYAPDSIRGAYVNLESYEYASGMADLGDMEES---------------EDVEYVIDTVESVVSAVMSDGKIPIMLGGEHSITVGAVRALPK---DVDLVIVDAHSDFRSSYMG-NKYNHACVTRRALD-----------------LLGEGRITSIGIRSVSREEFEDPDFRKVSFISSFDVKKNGIDKYIEEVDR-----KSRRVYISVDMDGIDPAYAPAVGTPEPFGLADTDVRRLIERLSY--KAVGFDIVEFSPLYD-NGNTSMLAAKLLQVFIASREKYYKE. 303
21 -66.8002a0m_A mol:protein length:316 ARGINASE SUPERFAMILY PROTEIN  ali model follow..  19  25.DIVIIGFPYDEGGGRAGAKKGPAAFRFFLQRLGSVNNLELNVDASHLKLYDAGDIT--------ASTLEEAHEKLESKVFTVLARGAFPFVIGGGNDQSAPNGRAMLRAFPDVGVINVDSHLDVRPPLQD-GRVHSGTPFRQLLEES---------------SFSGKRFVEFACQGSGALHAQYVRDHQGHLMWLSEVRKKGAVAALEDAFGLT----GKNTFFSFDVDSLKSSDMPGVSCPAAVGLSAQEAFDMCFLAGKTPTVMMMDMSELNPLVE-EYRSPRVAVYMFYHFVLGFATRPKP. 306
22 -66.2004rhm_A mol:protein length:351 Arginase  ali model follow..  19  16FSKFLMNVKGVTPGSDWANRLGPVALFGYGAGMPRRAAELTIHDKGPIECPPETVMFMDEAAGTETPTSDEWYLGSLEASTELLEKGYVPVSVGGDGSATLSMVEAYKRLFPDIVIVHFDAHPDVSD---------PRSPLRVLLDKGL-----------------LKGVVSVGNRQVSSEDRKVRKLHKMFYMDMHAIYSKGLFCIRDIR-------NDYPVFISIDADVLDPAFAPAVDSPVAGGLSTRDLLHIMNGIRGP-KVVGIDVYGYNPDLDNVGLTAIALSKIIKEGILKAYSISTHT 320
23 -63.9004rhi_A mol:protein length:351 Arginase  ali model follow..  18  21.MNVKGVTPRG---SDWANRLGPVALFGYGAGMPRRAPELTIHDKGPIECPPETVMFMPVAAGTETPTSDEWYLGSLEASTELLEKGYVPVSVGGDGSATLSMVEAYKRLFPDIVIVHFSARPSVSD---------PRSPLRVLLDKGL-----------------LKGVVSVGNRQVSSEDRKVRKLHKMFYMDMHAIYSKGLFCIRDIR-------NDYPVFISIDASVLDPAFAPAVDSPVAGGLSTRDLLHIMNGIRGP-KVVGIDVYGYNPDLDNVGLTAIALSKIIKEGILKAYSISTHT 320
24 -58.3001xfk_A mol:protein length:336 Formimidoylglutamase  ali model follow..  20  44.GVALIGFECDAGKGRTGAKHAPSLIKQALANLAWHH-PIPIYDLGNIRCEG--------------DELEQAQQECAQVIQQALPHA-RAIVLGGGHEIAWATFQGLAQHFPRIGIINFDAHFDLRTFESELAPVSSGTPFNQIHHFCQQQ--------------WDFHYACLGVSRATPALFERADKLGVWYVEDKAFSPLSLKDHLTQLQHFI--DDCDYLYLTIDLDVFPAASAPGVSAPAARGVSLEALAPYFDRILHKNKLMIADIAEYNPSFDIDQHTARLAARLCWDIANAMAEQVQSI 333
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I. and Godzik A Connecting the Protein Structure Universe by Using Sparse Recurring Fragments. Structure (Camb.) (2005) Aug;13(8):1213-24