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Query: 2bwn_A mol:protein length:401 5-AMINOLEVULINATE SYNTHASE, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDYNLALDKAIQKLHDEGRYRTFIDIEREKGAFPKAQWNRPDGGKQDITVWCGNDYLGMGQHPVVLAAMHEALEAVGAGSGGTRNISGTTAYHRRLEAEIAGLHQKEAALVFSSAYNANDATLSTLRVLFPGLIIYSDSLNHASMIEGIKRNAGPKRIFRHNDVAHLRELIAADDPAAPKLIAFESVYSMDGDFGPIKEICDIAEEFGALTYIDEVHAVGMYGPRGAGVAERDGLMHRIDIFNGTLAKAYGVFGGYIAASARMVDAVRSYAPGFIFSTSLPPAIAAGAQASIAFLKTAEGQKLRDAQQMHAKVLKMRLKALGMPIIDHGSHIVPVVIGDPVHTKAVSDMLLSDYGVYVQPINFPTVPRGTERLRFTPSPVHDLKQIDGLVHAMDLLWARCALast
1 -110.0002bwn_A mol:protein length:401 5-AMINOLEVULINATE SYNTHASE  ali model  100  1MDYNLALDKAIQKLHDEGRYRTFIDIEREKGAFPKAQWNRPDGGKQDITVWCGNDYLGMGQHPVVLAAMHEALEAVGAGSGGTRNISGTTAYHRRLEAEIAGLHQKEAALVFSSAYNANDATLSTLRVLFPGLIIYSDSLNHASMIEGIKRNAGPKRIFRHNDVAHLRELIAADDPAAPKLIAFESVYSMDGDFGPIKEICDIAEEFGALTYIDEVHAVGMYGPRGAGVAERDGLMHRIDIFNGTLAKAYGVFGGYIAASARMVDAVRSYAPGFIFSTSLPPAIAAGAQASIAFLKTAEGQKLRDAQQMHAKVLKMRLKALGMPIIDHGSHIVPVVIGDPVHTKAVSDMLLSDYGVYVQPINFPTVPRGTERLRFTPSPVHDLKQIDGLVHAMDLLWARCA 401
2 -102.0005txr_B mol:protein length:491 5-aminolevulinate synthase, mitochondrial  ali model follow..  48  14FDYEGLIDSELQKKRLDKSYRYFNNINRLAKEFPLA---HRQREADKVTVWCSNDYLALSKHPEVLDAMHKTIDKYGCGAGGTRNIAGHNIPTLNLEAELATLHKKEGALVFSSCYVANDAVLSLLGQKMKDLVIFSDELNHASMIVGIKHANVKKHIFKHNDLNELEQLLQSYPKSVPKLIAFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGLYGPHGAGVAEHCDFEDRVDMITGTLGKSFGSVGGYVAASRKLIDWFRSFAPGFIFTTTLPPSVMAGATAAIRYQRCHIDL--RTSQQKHTMYVKKAFHELGIPVIPNPSHIVPVLIGNADLAKQASDILINKHQIYVQAINFPTVARGTERLRITPTPGHTNDLSDILINAVDDVFNELQ 431
3 -101.0005vnx_A mol:protein length:393 8-amino-7-oxononanoate synthase  ali model follow..  31  1MNLLDTLQRGLADLDAQGLRRVRRTADSACDA-------HMTVNGREIVGFASNDYLGLAAHPKLVAAFAEGAQRYGSGSGGSHLLGGHSRAHAKLEDELAGFAGAPRALYFSTGYMANLAAVTAL--AGKDATIFSDALNHASLIDGTRLSRATVQVYPHADTATLGALLEACT-SQTKLIVTDTVFSMDGDIAPLAELLALAERHGAWLVVDDAHGFGVLGPQGRGALAAAALRSPHLVYVGTLGXAAGVAGAFVVAHETVIEWLIQRARSYIFTTAAPPAVAHAVSASLKVIAGDEGDARRAHLAALIERTRALLRRTRWQPVDSHTAVQPLVIGSNEATLAAMRALD-AHGLWVPAIRPPTVPAGTSRLRISLSAAHSFDDLARLETALLRASEEA. 393
4 -101.0005jay_A mol:protein length:402 8-amino-7-oxononanoate synthase  ali model follow..  32  3MHLLDTLAEGLKEIDARGLRRRRRTADTPCAA-------HMTVDGRAIIGFASNDYLGLAAHPQLIAAIAEGAQRYGAGSGGSHLLGGHSRAHAQLEDDLAEFVGNARALYFSTGYMANLATLTAL--AGRGTTLFSDALNHASLIDGARLSRADVQIYPHCDTDALSAMLEASD-ADVKVIVSDTVFSMDGDIAPLPRLLELAEQHGAWLIVDDAHGFGVLGPQGRGAIAQAALRSPNLISIGTLDKAAGVSGAFVAAHETVIEWLVQRARPYIFTTASVPAAAHAVSASLRIIGGEEGDARRAHLQQLIGRTRAMLKATPWLPVDSHTAVQPLIIGANDATLEIAATLD-RAGLWVPAIRPPTVPTGTSRLRISLSAAHSQADLDRLEAGLQQLGAKAA 396
5 -101.0003a2b_A mol:protein length:398 Serine palmitoyltransferase  ali model follow..  28  5LGEKISQFKIVEELKAKGLYAYFRPIQSKQDT-------EVKIDGRRVLMFGSNSYLGLTTDTRIIKAAQDALEKYGTGCAGSRFLNGTLDIHVELEEKLSAYVGKEAAILFSTGFQSNLGPLSCL--MGRNDYILLDERDHASIIDGSRLSFSKVIKYGHNNMEDLRAKLSRLPEDSAKLICTDGIFSMEGDIVNLPELTSIANEFDAAVMVDDAHSLGVIGHKGAGTASHFGLNDDVDLIMGTFSKSLASLGGFVAGDADVIDFLKHNARSVMFSASMTPASVASTLKALEIIQNEPEH--IEKLWKNTDYAKAQLLDHGFDLGATESPILPIFIRSNEKTFWVTKMLQ-DDGVFVNPVVSPAVPAEESLIRFSLMATHTYDQIDEAIEKMVKVFKQAE 393
6 -101.0002w8j_A mol:protein length:427 SERINE PALMITOYLTRANSFERASE  ali model follow..  32  24LSKFDGLIAERQKLLDSGVTDPFAIVMEQVK-----SPTEAVIRGKDTILLGTYNYMGMTFDPDVIAAGKEALEKFGSGTNGSRMLNGTFHDHMEVEQALRDFYGTTGAIVFSTGYMANLGIISTL--AGKGEYVILDADSHASIYDGCQQGNAEIVRFRHNSVEDLDKRLGRLPKEPAKLVVLEGVYSMLGDIAPLKEMVAVAKKHGAMVLVDEAHSMGFFGPNGRGVYEAQGLEGQIDFVVGTFSKSVGTVGGFVVSNHPKFEAVRLACRPYIFTASLPPSVVATATTSIRKLMTAHEK--RERLWSNARALHGGLKAMGFRLGTCDSAIVAVMLEDQEQAAMMWQALL-DGGLYVNMARPPATPAGTFLLRCSICAEHTPAQIQTVLGMFQAAGRAVG 416
7 -101.0001bs0_A mol:protein length:384 PROTEIN (8-AMINO-7-OXONANOATE SYNTHASE)  ali model follow..  29  1MSWQEKINAALDARRAADALRRRYPVAQGAGR-------WLVADDRQYLNFSSNDYLGLSHHPQIIRAWQQGAEQFGIGSGGSGHVSGYSVVHQALEEELAEWLGYSRALLFISGFAANQAVIAAM--MAKEDRIAADRLSHASLLEAASLSPSQLRRFAHNDVTHLARLLASPC-PGQQMVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRGSCWLQKV--KPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQLAEKLR-QQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG.... 384
8 -100.0002x8u_A mol:protein length:412 SERINE PALMITOYLTRANSFERASE  ali model follow..  27  4LSKFDPLIAEREALLATGVRDPYAIVMDKV-----LSPTEAMINGRKTILLGTYNYMGMTFDPDVIAAGKQALDEFGSGTTGSRVLNGTYQGHKACEDALKEFYGTEHAIVFSTGYQANLGMISTL--AGKGDYIILDADSHASIYDGCWLGDAEIVRFRHNSVEDLDKRLGRLPAEAGKLVVLEGVYSMMGDIAPLQEMVAVSKKHGAMILVDEAHGMGFFGEHGRGVFEEAGVEADVDFVVGTFSKSVGTVGGFCVSNHPKFEVLRLVCRPYVFTASLPPSVVATAATSIRKLMHAGDK--RAHLWKNSRRLHQGLRDMGYKLGTAQSAIIAVILTDMAQAVALWQGLL-EAGLYVNTARPPATPAGMFLLRCSLCAEHSDEQVEQILGMFESAGRATG 396
9 -99.2004bmk_A mol:protein length:442 SERINE PALMITOYLTRANSFERASE  ali model follow..  32  40LSKFDGLIAERQKLLDSGVTDPFAIVMEQVK-----SPTEAVIRGKDTILLGTYNYMGMTFDPDVIAAGKEALEKFGSGTNGSRMLNGTFHDHMEVEQALRDFYGTTGAIVFSTGYMANLGIISTL--AGKGEYVILDADSHASIYDGCQQGNAEIVRFRHNSVEDLDKRLGRLPKEPAKLVVLEGVYSMLGDIAPLKEMVAVAKKHGAMVLVDEAHSMGFFGPNGRGVYEAQGLEGQIDFVVGTFSASVGTVGGFVVSNHPKFEAVRLACRPYIFTASLPPSVVATATTSIRKLMTAHEK--RERLWSNARALHGGLKAMGFRLGTCDSAIVAVMLEDQEQAAMMWQALL-DGGLYVNMARPPATPAGTFLLRCSICAEHTPAQIQTVLGMFQAAGRAVG 432
10 -98.9003tqx_A mol:protein length:399 2-amino-3-ketobutyrate coenzyme A ligase  ali model follow..  31  5QEILSQLNKEIEGLKKAGLYKSERIITSPQNA-------EIKVGEKEVLNFCANNYLGLADHPALIKTAQTVVEQYGFGMASVRFICGTQTIHKELEKDISEFLGTDDTILYSSCFDANGGLFETL--LGPEDAIISDELNHASIIDGIRLCKAQRYRYKNNAMGDLEAKLKEADEKRFKLIATDGVFSMDGIIADLKSICDLADKYNALVMVDDSHAVGFIGENGRGTPEYCGVADRVDILTGTLGKALGASGGYTSGHKEIIEWLRNRSRPYLFSNTVAPVIVATSLKVLELLKTE-GPQLRKQLQENSRYFRAGMEKLGFQLVPGNHPIIPVMLGDAQLATNMADHLL-QEGIYVVGFSYPVVPMGKARIRVQMSAVHTQQQLDRAIEAFGQVGKKLG 397
11 -98.8001fc4_A mol:protein length:401 2-AMINO-3-KETOBUTYRATE CONENZYME A LIGASE  ali model follow..  31  6GEFYQQLTNDLETARAEGLFKEERIITSAQQADITV------ADGSHVINFCANNYLGLANHPDLIAAAKAGMDSHGFGMASVRFICGTQDSHKELEQKLAAFLGMEDAILYSSCFDANGGLFETL--LGAEDAIISDALNHASIIDGVRLCKAKRYRYANNDMQELEARLKEAREARHVLIATDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVGFVGENGRGSHEYCDVMGRVDIITGTLGKALGASGGYTAARKEVVEWLRQRSRPYLFSNSLAPAIVAASIKVLEMVEAGSEL--RDRLWANARQFREQMSAAGFTLAGADHAIIPVMLGDAVVAQKFARELQ-KEGIYVTGFFYPVVPKGQARIRTQMSAAHTPEQITRAVEAFTRIGKQLG 398
12 -96.6003wy7_A mol:protein length:404 8-amino-7-oxononanoate synthase  ali model follow..  31  22LSPLAWLADIEQRRRAEGLRRELR----------------VRPPVAAELDLASNDYLGLSQHPDVLDGGVEALRTWGGGAGGSRLVTGNTELHEAFEHQLASFLGAESALVFSSGYTANLGALVAL--SGPGSLIVSDALSHASLVDACRLSRARVVVSPHRDVDAVDAALAART-EERAVVVTESVFSADGDLAPLRDLHAVCRRHGALLLVDEAHGLGVRGTRGQGLLHEVGLAGAPDVMTTTLSKALGSQGGAVLGPEAVRAHLIDTARSFIFDTGLAPAAVGAASAALRVLDAEPQR--ARAVLDRAAELAT----IAGVTEAPVSAVVSVILGDPEIAVGAAAACL-DRGVRVGCFRPPTVPAGTSRLRLAARASLTDDEMALARQVLTDVLATA. 396
13 -93.4004iw7_A mol:protein length:399 8-amino-7-oxononanoate synthase  ali model follow..  22  17.NAMLNLQDKYTQYQRDNLLRELTPF----------------IKDDSIIDFTTSDYLNLSSAHNLKHAIVNGFDKYGFGSKGSNIVCGYTDETQQFEHEFAKFINYPRAIFFSSGFMANLAIYSTL--FSKHDSIFADKYIHASIIDGIKLSQAKLRRYKHQQLSQLQDIYDG-----KSFITTEGVFSTSGSITQLDKLAKITPEK---LIVDEAHSFGVLGKNGRGAINSFRISKNCLICVFPLGKAFGGVGAVVCTTEAIAEYLIQFARNYIYTTALPPMILKAALIQLKNLENVNDN--RARLQQNITFFNELCDAKDLELVSKDSPIRSIQLNNANLAIRLKDKLF-ENKIIVSCFRYPTVPKDQAILRFSLHSNNTFDQIQQALEIISKEVKYEY 389
14 -93.3002wk7_A mol:protein length:393 CAI-1 AUTOINDUCER SYNTHASE  ali model follow..  26  33.......................................LGKQASPDDIILQSNDYLALANHPLIKARLAKSLLEEQQSLFMSASFLQNDYDKPMIEKRLAKFTGFDECLLSQSGWNANVGLLQTI--CQPNTNVYIDFFAHMSLWEGARYANAQAHPFMHNNCDHLRMLIQR---HGPGIIVVDSIYSTLGTIAPLAELVNISKEFGCALLVDESHSLGTHGPNGAGLLAELGLTREVHFMTASLAKTFAYRAGAIWCNNEVNRCVPFISYPAIFSSTLLPYEAAGLETTLEIIESADNR--RQHLDRMARKLRIGLSQLGLTI-RSESQIIGLETGDERNTEKVRDYLE-SNGVFGSVFCRPATSKNKNIIRLSLNSDVNDEQIAKIIEVCSDAVNYGD 385
15 -91.3003hqt_A mol:protein length:409 CAI-1 autoinducer synthase  ali model follow..  26  47.......................................LGKQASPDDIILQSNDYLALANHPLIKARLAKSLLEEQQSLFMSASFLQNDYDKPMIEKRLAKFTGFDECLLSQSGWNANVGLLQTI--CQPNTNVYIDFFAHMSLWEGARYANAQAHPFMHNNCDHLRMLIQR---HGPGIIVVDSIYSTLGTIAPLAELVNISKEFGCALLVDESHSLGTHGPNGAGLLAELGLTREVHFMTASLAKTFAYRAGAIWCNNEVNRCVPFISYPAIFSSTLLPYEAAGLETTLEIIESADNR--RQHLDRMARKLRIGLSQLGLTI-RSESQIIGLETGDERNTEKVRDYLE-SNGVFGSVFCRPATSKNKNIIRLSLNSDVNDEQIAKIIEVCSDAVNYGD 399
16 -26.6002e7i_A mol:protein length:371 Sep-tRNA:Cys-tRNA synthase  ali model follow..  11  1...............................................MFKRETKDFINIQTGGKLTEEARQALLEWGDGYSVCDFCT-TPPIHDFIHNQLPKFLGCDVARVTNGAREAKFAVMHSLAK--KDAWVVMDENCHYSSYVAAERAGLNIALVPKTTPENFAQTIEETKKRGEVLALITYPDGNYGNLPDVKKIAKVCSEYDVPLLVNGAYAIGRMPVSLKEI--------GADFIVGSGHKSMAASGGVMGMKEEWAEIVLRRSEKYLLGCTARGATIITLMASFPHVRERIKRWDEE--VEKARRFAAEMEKLGIKQLGDNAEVLYEISKKAKGGRFFLYRELKSRKIHG------IKPGLTRYFKLS-TYGLSDEEVDYVLNAFKEIIEKYS 371
17 -20.7002fm1_A mol:protein length:355 L-allo-threonine aldolase  ali model follow..  16  3...........................................SDKIMIDLRSDTVTK---TEEMRKAMAQA--------EVGDDVYGEDPTINELERLAAETFGKEAALFVPSGTMGNQVSIMAHTQ--RGDEVILEADSHIFWYEVAVLSGVMPHPVPGKNPDDVRKAIRPRNIHRTSLIAIENTHNRSGPLENIKEICTIAKEHGINVHIDGARIFNASIASGVPVKE---YAGYADSVMFCLSKGLCAVGSVVVGDRDFIERARKARKMLGGGMRQAGVLAAAGIIALT-----KMVDRLKEDHENARFLALKLKEIGVNPEDVKTNMVILRTDNLKVNAHGFIEALRNSGVLA-------NAVSDTEIRLVTHKDVSRNDIEEALNIFEKLFRKFS 349
18 -20.3006DK6 Entity 1(prereleased)  ali follow..  12  1..........MALINENFLKLKAGYLFPEIARRVKAFTEGNPEAAQRLIRCGIGD--TEALPEAVRYAMHEAVDELGNRSTFKGYEQGYDFLRNAIADNDYKARGLPDEIFISDG--SKCDTGNILDIFGQGNTIAITDPVYPVYVDTNVMIGNTGEADENGAYAGLVGFVPDIPQEKADLIYLCYPNNPTGAVATLEAWVKYARENGSVLLYDAAYEAFIQDPTIPHSIFEIEGARDCAIEFRSFSKNGGFTGAYVVIPKSLMGRKKNGEAQAL-FNGASYIVQKGAEALYTDEGKSQTKALIEHYMGNAALLVEACKNAGLSVFGGVNAPY-VGCPAGLTSWQMFDKMLNEANVVITP------SAGEGYFRISAFN--SRANVEEVCRRIAAL..... 410
19 -20.3004lnj_A mol:protein length:333 Low-specificity L-threonine aldolase  ali model follow..  13  1...............................................MIDLRSDTVTR---SRAMLEAMMAA--------PVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCE--RGEEYIVGQAAHAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPLKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKE---ITQYCDSFTICLSKGLGTVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMYALK-----NNVARLQEDHDNTAWMAEQLREAGADVMRQDTNMLFVRV--GEENAAALGEYMKARNVLI---------NASPIVRLVTHLDVSRAQLAEVAAHWRAFLAR.. 333
20 -20.1003pj0_A mol:protein length:359 Lmo0305 protein  ali model follow..  13  22..............................................................PRNVGVLTEALQNIDDNLESD--IYGNGAVIEDFETKIAKILGKQSAVFFPSGTMAQQIALRIWADRKENRRVAYHPLSHLEIHEQKELQQITPLLLGTANQLLTIDDIKSLREPVSSVLIELPQREIGGQLPALEKISEYCHEQGISLHLDGARLWEITPFYQKSAEE---ICALFDSVYVSFYKGIGGAGAILAGNDDFVQEAKIWKRRYGGDLISLYPYILSADYYFE-----KRIGKMAEYFEAAKGLAERFNSCSTVPEVPVSNMFHVYFNSADEIGAILTKIQDETGVGISGYLQEKS-ADVCAFEVSVGDAFAEIPAKNLELVFRCLEKEL. 359
21 -20.0003asa_A mol:protein length:400 LL-diaminopimelate aminotransferase  ali model follow..  12  23...................................VAQFRLENPQHTVINLSIGD--TQPLNASVAEAFASSIARLSSPTTCRGYDFGLPALRQKLSEDFYRGFVDAKEIFISDG--AKVDLFRLLSFFGPNQTVAIQDPSYPAYLDIARLTGAKEIIALPCLQEN-AFFPEFPEDTHIDILCLCSPNNPTGTVLNLRAIVHYAIEHEILILFDAAYSTFISDPSLPKSIFEIPDARFCAIEINSFSKPLGFAGGWTVIPQELTYADGHFV---FLSTTFNGASIPAQEAGVAGLSILPQLEAIHYYRENSDLLRKALLATGFEVFGGEHALWVKPTQANISDRDLFDFFLREYHIAITP------RSGSGFVRFSSLG--KREDILAACERLQMAPALQS 394
22 -19.9003wlx_B mol:protein length:333 Low specificity L-threonine aldolase  ali model follow..  14  1...............................................MIDLRSDTVTR---SRAMLEAMMAA--------PVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCE--RGEEYIVGQAAHAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPLKEAWEFTRERNLALHVDGARIFNAVVAYGCELKE---ITQYCDSFTICLSKGLGTVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGIYALK-----NNVARLQEDHDNAAWMAEQLREAGADVMRQDTNMLFVRV--GEENAAALGEYMKARNVLI---------NASPIVRLVTHLDVSREQLAEVAAHWRAFLAR.. 333
23 -19.7003lws_A mol:protein length:357 Aromatic amino acid beta-eliminating lyase/threonine aldolase  ali model follow..  14  14........................................................GQISGHGKRNVGVLKTAFAAVADEMASDQY-GTGAIIEPFEQKFADVLGMDDAVFFPSGTMAQQVALRIWSDETDNRTVAYHPLCHLEIHEQKELHPIETILVGAADRLMTLDEIKALPDIACLLLELP---EIGGVAPALETISRYCRERGIRLHLDGARLFEMLPYYEKTAAE---IAGLFDSIYISFYKGLGGAGAILAGPAAFCQTARIWKRRYGGDLISLYPYIVSADYYYE-----LRKDRMGQYYEQAKQLAEQFNALPTTPEVPVSNMFHLHFGQAADISPKLEQVQEETGLGFVG------YLVDKDGYCSTEISVGDAYGELDQQTRDAGFARLR 353
24 -19.6003qgu_A mol:protein length:449 LL-diaminopimelate aminotransferase  ali model follow..  11  39......RNENFGKLRAGYLFPEIARRRKAH---------QEKNPDAKIISLGIGD--TEPLPKYIADAMAKAAAGLATREGYSGYEQGQGALREAVASTFYGHAGRADEIFISDG--SKCDIARIQMMFGSKPTVAVQDPSYPVYVDTSVMMGMTGDHEYMVCNPDNHFFPDLSKAKRTDIIFFCSPNNPTGAAATLTELVNFARKNGSILVYDAAYALYISNPDCPKTIYEIPGADEVAIETCSFSKYAGFTGGWTVVPKALKYANGEPVHADWCFNGASNIVQAGGLACLQPEGLKEMNAMIKFYKENAQILKTTFTEMGFSVYGGDDAPYIWVGFPGKPSWDVFAEILERCNIVTTP------PAGEGFVRASAFG--SRENILEAVRRFKEAYGKRN 441
25 -19.4004wbt_A mol:protein length:376 Probable histidinol-phosphate aminotransferase  ali model follow..  17  4MSAFSRFTPLIQSLPASVPFVGPEALERQHGR-------------KIAARIGANE---FGPAPSVLLAIRQAAGDTWKYADPE---------NHDLKQALARHLGTSPANIAIGEGIDGLLGQIVRLVVEAGAPVVTSLGGYPTFNYHVAGHGGRLVTVPYADREDLEGLLAAVGRENAPLVYLANPDNPMGSWWPAERVVAFAQALTTLLVLDEAY-CETAPRDALPPIESLIDKPNV-IRARTFSKAYGLAGGYTLSTPGTAQAFDKIRNHF----GMSRIGVAAAIAALA--DQDYLKEVTLKIANSRQRIGRIAADSGLAPLPSATNFVAVDCGDASYARAIVDRLMSDHGIFIRMPGVAPLNR----IRISTA---PDAEMDLLAAALPEVIRSLA 374
26 -19.3006cbk_A mol:protein length:424 Neamine transaminase NeoN  ali model follow..  16  29...........................................SGAWLTDESGFRWIDFDGDPVVAEAVARAATG------ADGTATGWSRRVDAVLERLHALCGGEVVGLFRSGTAAVRAAVLAVREATGRPLLLSAGY-HGYYPSEAPLENADGVVDFFFDLGLLRELLRAPERVAAVVVSPDHMHLSPG----YRELRRLCSAAGVVLVADEV--VGL--RYAPGLSTAELLAPDV-----VVAKGMA--NGHVGGSRRLLKPLKEVSFTSFFE----PTILAAADAALARVATGEPQRAVREAGDRLRHARKALDDASLPVEIAGDGTFFQFVPATEELEEALYGAANAEGLLFYA-------------NQGVSAAFDEAVLGEAERRFARVCERLA 372
27 -19.2004fl0_A mol:protein length:456 Aminotransferase ALD1  ali model follow..  12  40......RNVNLEKLKNNYLFPEINRRELEH---------IEKHPNVQLISLGTGD--TEPIPEQITSHMSNFAHGLSTVEGYRGY-QGNKTLRKAIAETFYRDLHVKNEVFVSDGAQSDISRLQLL--LGSNVTIAVQDPTFPAYIDSSVIIGQTGHFHEKTKGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASLHQLVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVA-IEVSSFSKFAGFTGGWSIIPDELLYSNGFPIINDFSFNGASNIAQAGGLACLSSGGLKEIRSVNNYYKENRKILMDTLVSLGLKVYGGVNAPYLWVHFKGSKSWDVFNEILENTHIITVP------PGGEEYLRISGFG--RRDHIVEASKRLQNFFNTRT 443
28 -19.1006cbm_A mol:protein length:438 Neamine transaminase NeoN  ali model follow..  16  45...........................................SGAWLTDESGFRWIDFDGDPVVAEAVARAATG------ADGTATGWSRRVDAVLERLHALCGGEVVGLFRSGTAAVRAAVLAVREATGRPLLLSAGY-HGYYPSEAPLENADGVVDFFFDLGLLRELLRAPERVAAVVVSPDHMHLSPG----YRELRRLCSAAGVVLVADEV--VGL--RYAPGLSTAELLAPDV-----VVAKGMA--NGHVGGSRRLLKPLKEVSFTSFFE----PTILAAADAALARVATGEPQRAVREAGDRLRHARKALDDASLPVEIAGDGTFFQFVPATEELEEALYGAANAEGLLFYA-------------NQGVSAAFDEAVLGEAERRFARVCERLA 388
29 -19.0006cbo_A mol:protein length:439 C-6` aminotransferase  ali model follow..  13  48...........................................SGAYLTDPDGRRWIDFDGDEEVAEAIARAARG------RSGVGTAWSPVLDSLLGQLQEVCGGDVVGLYRTGTAALRSVT-CAVRDARDRSIVLSSGYHGYHCDEPFTPNQHGIVEFLFDLDVLAEWLSRPEQ---AAVVISPDHMHLGE---YTEFTRLTKEADVPVIADEV--VGLRYRAG-------LSTPLLDPAVWIVAKCLA--NGSVGGDAHLLAALEDVSFTSYFE----PTAMAAATTTLRRMATGEPQQAIRAAGDRIAHTRAAFANAGVPIDLAGNGNLFQFVCADDEVADAFHAAAAAEGLLFFE-------------NQTPSAAFTDEVVEDACGRIDRVSAALT 389
30 -18.7005x6b_I mol:protein length:417 O-phospho-L-seryl-tRNA:Cys-tRNA synthase  ali model follow..  12  63..............................................................KEAKKAVYEYWDGYSVCDYCHGRLD-TCPPIKDFLEDIAKFLNMDCARPTHGAREGKFIVMHAI--CKEGDYVVLDKNAHYTSYVAAERAKLNVAEVGYENLEGYKEVIDNLEDKGKGLILLTHVDGEYGNLNDAKKVGKIAKEKGIPFLLNCAYTVGRMPVNGKEV--------KADFIVASGHKSMASAPGILAFSEEFSDKITKTSEKFMLGCTSRGLPIVTLMASFPHVVERVKKWDEEL--KKTRYVVDELEKIGFKQLGIKPKEHDLIKFETPVLDEIAKKDKRRGFFFYDELKKRGIAGVTKEIKMSVYGL-EWEQVEYVVNAIKEIVESC. 410
31 -18.6003b46_A mol:protein length:447 Aminotransferase BNA3  ali model follow..  15  32....................NTAKDVWSLTNEAAAKAANNSKNQGRELINLGQGF--SYSPPQFAIKEAQKALDIPMVNQYSP--TRGRPSLINSLIKLYSPIYNTEENVTVTTG--ANEGILSCLGLLNAGDEVIVFEPFFDQYIPNIELCGGKVVYVPGEEWTIDFEQFEKAITSKTKAVIINTPHNPIGKVEELTTLGNICVKHNVVIISDEVYEHLYFTDSFTRIATLSPEIGQLTLTVGSAGKSFAATGGWVLSLNAELLSYAAKAHTRICFASPSPLQEACANSINDALKIGYFEKMRQEYINKFKIFTSIFDELGLPYTAPEGTYFVLVILNKGKDFRISHWLINELGVVAIP-IKEHEKAAENLLRFAVCK--DDAYLENAVERLKLLKDYL. 447
32 -18.6002z1z_A mol:protein length:432 LL-diaminopimelate aminotransferase  ali model follow..  11  26......RNSNMSKLQAGYLFPEIARRRSAH---------LLKYPDAQVISLGIGD--TEPIPEVITSAMAKKAHELSTIEGYSGY-QGAKPLRAAIAKTFYGGLGIGDDVFVSDG--AKCDISRLQVMFGSNVTIAVQDPSYPAYVDSSVIMGQTGQFNTDVQKYGNIEYMRCTPENRTDIIFFCSPNNPTGAAATLTQLVEFAKKNGSIIVYDSAYAMYMSDDNPRSIFEIPGAEEVA-METASFSKYAGFTGGWTVIPKKLLYSDGFPVAKDFCFNGASNISQAGALACLTPEGLEAMHKVIGFYKENTNIIIDTFTSLGYDVYGGKNAPYVWVHFPNQSSWDVFAEILEKTHVVTTP------PGGEGFVRVSAFG--HRENILEACRRFKQLYK... 426
33 -18.6003wgb_A mol:protein length:341 L-allo-threonine aldolase  ali model follow..  16  2...........................................SHMRYIDLRSDTVTQ---TDAMRQCMLHA--------EVGDDVYGEDPGVNALEAYGADLLGKEAALFVPSGTMSNLLAVMSHCQ--RGEGAVLGSAAHSAVLGSVALQPVPMQADGSLALADVRAAIAPDDVHFTPTRLVCLENTHNGKVLPLREMRELVDEHGLQLHLDGARLFNAVVASGHTVRE---LVAPFDSVSICLSKGLGAVGSLLVGSHAFIARARRLRKMVGGGMRQAGILAQAGLFALQ-----QHVVRLADDHRRARQLAEGLAALGIRLDLAQVQTNMVFLQLTSGESAPLLAFMKARGILF---------SGYGELRLVTHLQIHDDDIEEVIDAFTEYLGA.. 341
34 -18.3003ly1_A mol:protein length:354 Putative histidinol-phosphate aminotransferase  ali model follow..  15  16.............................................DNPIRINFNE---LGMSPKAQAAARDAVVKANRYAKNEI---------LMLGNKLAAHHQVEAPSILLTAGSSEGIRAAIEAYASLEAQLVIPELTYGDGEHFAKIAGMKVTKVKAFDIEGLKAAVA--AYSGPSIVYLVNPNNPTGTITPADVIEPWIAS-NTMFIVDEAYAEFVNDPRFRSISPMITQGAENIILLKTFSKIHAMAGGYAVAHPTVIALMGRYVAGE----KINFSGVDAALASMN--DSAFITYSKKSNDVSRQILLKALEDLKLPYLPSEGNFVFHQLVVPLKDYQ---THMADAGVLIGRAFPPA----DNWCRISLG---TPQEMQWVADTMREFRKK.. 351
35 -18.1003hdo_A mol:protein length:360 Histidinol-phosphate aminotransferase  ali model follow..  13  24...........................................DIASWIKLNTNE---YPPSPEVVKAILEELGP-----DGAALRIYPSASSQKLREVAGELYGFDPSWIIMANGSDEVLNNLIRAFAAEGEEIGYVHPSYSYYGTLAEVQGARVRTFGLTG-----RIAGFPERYEGKVFFLTTPNAPLGPSFPLEYIDELARRCAGMLVLDETYAEFAESNALELVRRHENV-----VVTRTLSKSYSLAGGLAIARPEVIAALDKIRDHY----NLDRLAQAACVAALR--DQAYLSECCRRIRETREWFTTELRSIGYDVIPSQGNY--LFATPPDRDGKRVYDGLYARKVLVRHFSDPLLAH----MRISIG---TREEMEQTLAALKEIGE... 353
36 -18.1003ezs_A mol:protein length:376 aminotransferase AspB  ali model follow..  10  21...........................................PKKRGLDLGIGE--QFETPKFIQDALKNHTHSLNIYPKSAFEESLRAAQRGFFKRRFKIELKENELISTLGSREVLFNFPSFVLFDYQNPTIAYPNPFYQIYEGAAKFIKAKSLLMPLTKENDFTPSLNEKELQEVDLVILNSPNNPTGRTLSLISWVKLALKHDFILINDECYSEIYENTPPPSLLEACMLAGKNVLVIHSLSKRSSAPGGFIAGDSRLLEKYKAFRAYL--GYTSANAIQKASEAAWL--DDRHAEFFRNIYANNLKLARKIFKNTLIYPYS-------YVYLPVQNGENFAKTLYQNEGIITLPLYLGRNRIGADYVRLALVY--DTPLLEKPLEIIETYRENHA 376
37 -18.1002aeu_A mol:protein length:374 Hypothetical protein MJ0158  ali model follow..  14  32......................................................DLSGLSGGFLIDEKDKALLNTY---------IGSSYFAEKVNEYGLKHLGGNDKCVGFNRTSSAILATILALKP-KKVIHYLPELPGHPSIERSCKIVNAKYF-----ESDKVGEILNKIDKDTLVIITGSTMDLKVIELENFKKVINTAKNKEAIVFVDDASGARVRLLFNQPPALKLG----ADLVVTSTDKLMGPRGGLLAGKKELVDKIY--IEGTKFGLEAQPPLLAGIYRALKNFNLERIRKAFERAKNFDLSKIEKLNKELKAIDDN-KRVYKDDTINIKKLIEIGFNLLKNYGIITITVA--GMPGASKSLRIDLTSRDAER--NYIIKAIVESIKMAF 372
38 -18.0003h7f_A mol:protein length:447 Serine hydroxymethyltransferase 1  ali model follow..  18  18.......................APLAEVDPDIAELLAKELGRQRDTLEMIASENFVP----RAVLQAQGSVLNKYAEGLPGRRYYGGCEVVENLARDRAKALFGAEFANV--SGAQANAAVLHAL--MSPGERLLGLDLANGGHLTHGMRLNFSGKLYE--DMDAVRATALE---FRPKVIIAGW--SAYPRVLDFAAFRSIADEVGAKLLVDMAHFAGLVAAG-----LHPSPVPHADVVSTTVHKTLGGRSGLIVGKQQYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPE-FADRQRRTLSGARIIADRLMAPDVAKAGTDVHLVLVDLRDSPLDGQAAEDLLHEVGITVNRNAVPNDPRPTSGLRIGTPAL-GDTEFTEVADIIATALAT.. 407
39 -18.0001tpl_A mol:protein length:456 TYROSINE PHENOL-LYASE  ali model follow..  13  23...........................................ERLKKMQEAGYNTFLLNSKDIYIDLLTDSGTNAMSDKQWAGMMMGDEAY-YHLERTVQELFGFKHIVPTHQGRGAENLLSQLA--IKPGQYVAGNMYFTTTRYHQEKNGAVFVDIVRDIDLKKLQKLIDEKGAENIAYICLAVTVNLAGSMANMRAVRELTAAHGIKVFYDATENAYFIKEQEQGFENK-EMFSYADGCTMSGKKDCLVIGGFLCMNDDEMFSSAKELVVVYEGMPSYGGLAGRDMEAMAILREAMQYEYIEHRVKQVRYLGDKLKAAGVPIVEPVRRFCEHLTQDEFPAQSLAASIYVETGVRSNNVTGEHHRPKLETVRLTIRRVYTYAHMDVVADGIIKLYQH.. 430
40 -18.0002o1b_A mol:protein length:404 Aminotransferase, class I  ali model follow..  11  30..................................KTMGRKIEHGPLPLINMAVGI--DGPTPQGIIDHFQKALTIPENQKYGA--FHGKEAFKQAIVDFYQRQYNVEDEVCILYGTKNGLVAV-PTCVINPGDYVLLPDPGYTDYLAGVLLADGKPVPLEPPHYLPDWSKVDSQIIDKTKLIYLTYPNNPTGSTATFDEAIAKFKGTDTKIVHDFAYGAFGFDAKNPSILASENGKDVA-IEIYSLSKGYNMSGGFAVGNKDMIQALKKYQTHT--NAGMFGALQDAAIYALN--YDDFLEEQSNVFKTRRDRFEAMLAKADLPFVHAKGGIYVWLTPPGYDSEQFEQFLVQEKSILVAP------ENGNRYVRISLAL--DDQKLDEAAIRLTELAYLYE 398
41 -17.9006c3a_A mol:protein length:413 Uncharacterized protein  ali model follow..  55...........................................................ASQQSIVSRLPQLWYE----AEEGLQATYEKRFTEAFFQLHRQPTALVKNKTMLSYAASISTMVAGMFLKKERLAVTLIEPCFDNLYDVLANMDVPLYPIDESVFYDVDIYPELERRVRTDALFLVDPNNPTGFSLLFEEVVRFCKDHDKLLLIDFCFASFTLFEPELARFDMYELLENSGLAIEDTGKTWPVQDALITASDDIWETVYNLHTSVL--LNVSPFVLNMLTQYVRDSAADRLASVREVLTRNRECARKTLDGSILEYQEPVVKVS-FRVDHPELTATDVHRLLSADGVYVLPFYWSEPSKGDAYVRMALAR--EPEMFADAMALTRQVLDRHG 406
42 -17.9001svv_A mol:protein length:359 THREONINE ALDOLASE  ali model follow..  15  11...........................................AKPKPYSFVNDYSVG---HPKILDLMARD-------NMTQHAGYGQDSHCAKAARLIGELLERPDAHFISGGTQTNLIACSLALR--PWEAVIATQLGHISTHEAIEATGHKVVTAPCPDVADIESALHENRSEIPKLVYISTQYTKQ----ELEDISASCKEHGLYLFLDGARLASALSSPVNDLTLA-DIARLTDMFYIGATKAGGMGEALIILNDALKPNARHLIKQRGALMAKGWLLGIQFEVLMK---DNLFFELGAHSNKMAAILKAGLEACGIRLAWPSASNQLFPILENTMIAELNNDFDMYT----------PLKDGTCIMRLCTSWATEEKECHRFVEVLKRLVASTA 359
43 -17.8002x5d_A mol:protein length:412 PROBABLE AMINOTRANSFERASE  ali model follow..  13  2..........MAESRPARRFARIDRLPPYVFNITAELKMAARRRGEDIIDLSMGN--DGPTPPHIVEKLCTVAQR--EDTHGYSTSRGIPRLRRAISHWYRDRYDVESEAIVTIGSKEGLAHL-MLATLDHGDTILVPNPSYPIHIYGAVIAGAQVRSVPGIDFFNELERAIRESIPKPRMMILGFPSNPTAQCVEFERVVALAKQYDVMVVHDLAYADIVYDGWKAPSIMQVPGAKDIAVEFFTLSKSYNMAGGFMVGNPELVSALARIKSYH--DYGTFTPLQVAAIAALE--DQQCVRDIARQYQQRRDVLVKGLREAGWMVENPKASMYVWA--AHLGSLEFAKKLLQDAKVSVSP------DYGDDHVRFALIE--NRDRLRQAVRGIKAMFRADG 399
44 -17.7001kkj_A mol:protein length:419 Serine Hydroxymethyltransferase  ali model follow..  18  1......................MKYLPQQDPQVFAAIEQERKRQHAKIELIASENFVS----RAVMEAQGSVLNKYAEGYPGRRYYGGCEIVEELARERAKQLFGAEHANV--SGAQANMAVYFTVLE--HGDTVLGSHGGHLTHGSPVNFSGVQYNFVAYGDYDDVREKARL---HRPKLIVAAA--SAYPRIIDFAKFREIADEVGAYLMVDMAHIAGLVAAG-----LHPNPVPYAHFVTTTTHKTLGPRGGMILCQEQFAKQIDKAIFPGIQGGPLMHVIAAKAVAFGEALQDD-FKAYAKRVVDNAKRLASALQNEGFTLVGTDNHLLLVDLRPQQLTGKTAEKVLDEVGITVNKNTIPYDPESTSGIRIGTAAV-GLEEMDEIAAIIGLVLKN.. 386
45 -17.7003gbx_A mol:protein length:420 Serine hydroxymethyltransferase  ali model follow..  15  1...............SNAMLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTS----PRVMQAQGSQLNKYAEGYPGKRYYGGCEVVEQLAIDRAKELFGADYANV--SGSQANFAVYTALLQPGDTVLGMNLA-GHLTHGSPVNFSGKLYNIVPYGDYDEMAKLAKE---HKPKMIIGGF--SAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAG-----VYPNPVPHAHVVTTTTHKTLGPRGGLILAKGGDEELYKKLNSAVFAQGGPLMHVIAGKAVALKEAMEPEFKVYQQQVAKNAKAMVEVFLNRGYKVGGTENHLFLLDLVDKNLTGKEADAALGRANITVNKNSVPNDPKSTSGIRIGSPAV-KEAEVKELAGWMCDVLDN.. 395
46 -17.6002z61_A mol:protein length:370 Probable aspartate aminotransferase 2  ali model follow..  11  2..................LSKRLLNFESFEVMDILALAQKLESEGKKVIHLEIGE--DFNTPKPIVDEGIKSLKE---GKTHYTDSRGILELREKISELYKDKYKADDNIIITGG-SSLGLFFALSSIIDDGDEVLIQNPCYPCYKNFIRFLGAKPVFCD--TVESLEEALSD----KTKAIIINSPSNPLGEVID-REIYEFAYENIPYIISDEIYNGLVYEGKCYSAIEFDENLEKT-ILINGFSKLYAMTGGYVISNDEIIEAILKLQQNL--FISAPTISQYAALKAFEKETEREINSMIKEFDRRRRLVLKYVKDFGWEVNNPIGAYY-VFPNIGEDGREFAYKLLKEKFVALTP------SKGKNYIRISYAN--SYENIKEGLERIKEFLNK.. 370
47 -17.6006MME Entity 1(prereleased)  ali follow..  13  23...........................................ERLKKMQEAGYNTFLLNSKDIYIDLLTDSGTNAMSDKQWAGMMMGDEAY-YHLERTVQELFGFKHIVPTHQGRGAENLLSQLA--IKPGQYVAGNMYFTTTRYHQEKNGAVFVDIVRDIDLKKLQKLIDEKGAENIAYICLAVTVNLAGSMANMRAVRELTEAHGIKVFYDATENAYFIKEQEQGFENK-EMFSYADGCTMSGKKDCLVIGGFLCMNDDEMFSSAKELVVVYEGMPSYGGLAGRDMEAMAILREAMQYEYIEHRVKQVRYLGDKLKAAGVPIVEPVGG---VFLDARRFCEHLTQDEFPAQSLAASIYVETGVRPKLETVRLTIRRVYTYAHMDVVADGIIKLYQH.. 430
48 -17.5004r2n_A mol:protein length:367 Putative phenylalanine aminotransferase  ali model follow..  15  23.............................................PGAIKLASNE---FGPLPSVRAAIDRATDTVNRYPDNGC---------VQLKAALARHLGPDEHVAVGCGSVSLCQQL-VQVTASVGDEVVFGWRSFELYPPQVRVAGAIPIQVPLTDHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVHILIAIDEAYVEYIRDGMRPDSLGLVRAHNNV-VVLRTFSKAYGLAGGYAIGHPDVITALDKVYVPF----TVSSIGQAAAIASLD--AADELLARTDTVVAERARVSAELRAAGFTLPPSQANFVWLPLGSRTQDFV---EQAADARIVVRPYG-------TDGVRVTVA---APEENDAFLRFARRWRSD.. 353
49 -17.4005d95_A mol:protein length:454 Aminotransferase class-III  ali model follow..  13  52...........................................RGAVIVDADGEERLDFVADPDINEAVIRQLAD-GVAFAMP------TEHEIALAELLTEVPSLQQVRFTNSGTEAVMMAIKAARAYTGRPRIAKFDGCYHGSYDFAEVSTQSVVVLPFNDIDGTERLIEQHRDELAAVLI-DPNPRSLGLYPALQRLREITRAYGIVLIFDEVISLRS-----GGMQSVLGVTPDL----TAMGKIIG--GGFVGGSAEVMSVFDPTGGP---TFNANPVTMVAGLTAMRKLTPAEFDRLATLGQQLRAGVEEVLREAGVPGVTGYGSLFHIHLHQRPLADYRNSVLSAQERAFVGRVHEALMGRGTPALFGCLSTPMGVPEVEAFVDAFAAALQDAR 445
50 -17.4004wp0_A mol:protein length:472 Kynurenine--oxoglutarate transaminase 1  ali model follow..  11  25..........................................ASEHDVVNL-GQGFPDFPPPDFAVEAFQHAVSG-DFMLNQYTKTFGYPPLTKILASFFGELLGQERNVLVTVG--GYGALFTAFALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVEELELVASLCQQHDVVCITDEVYQWMVYGHQHISIASLPGMWERT-LTIGSAGKTFSATGGWVLGPDHIMKHLRTVHQNSVFHCPTQ-AVAESFEREQLLFRQPSSVQFPQAMQRCRDHMIRSLQSVGLKPIIPQGSYFLIT--DEPYDRRFVKWMIKNKGLVAIP-SVPHQKHFDHYIRFCFVK--DEATLQAMDEKLRKWKVELE 423
51 -17.3003get_A mol:protein length:365 Histidinol-phosphate aminotransferase  ali model follow..  13  30.............................................KEVIKLASNE---FGTPPKAIECLRQNANKAHLYPDDSM---------IELKSTLAQKYKVQNENIIIGAGSDQVIEFAIHSKLNSKNAFLQAGVTFAMYEIYAKQCGAKCYKTQSITHNLDEKKLYETHKDEIKLIFLCLPNNPLGECLDASEATEFIKGVDCLVVIDAAYNEFASFKDSKKHLEPCELIKEFDLYLGTFSKLYGLGGGYGIANANIISAFYKLRAPF----NVSNLALKAAVAAMD--DDEFTEKTLENNFSQMELYKEFAKKHNIKIIDSYTNFITYFFDEKNSTDLSEK--LLKKGIIIRNLK----SYGLNAIRITIG---TSYENEKFFTEFDKILR... 365
52 -17.3003p1t_A mol:protein length:337 Putative histidinol-phosphate aminotransferase  ali model follow..  13  16.............................................AQAVCLAFNE---EAVEPRVQAAIAAAAARINRYPFDAE---------PRVMRKLAEHFSCPDNLMLVRG---IDECFDRISAEFSSMRFVTAWPGFDGYRARIAVSGLRHFEIGLTDDLLLD-PNDLAQVSRDDCVVLANPSNPTGQALSAGELDQLRQR--GKLLIDETY-VDYSSFRARGLAYGENE-----LVFRSFSKSYGLAGGALFGPSELIAAMKRKQWFC----NVGTLDLHALEAALD--NDRAREAHIAKTLAQRRRVADALRGLGYRVASSEANFVLVENAAGERTLRF----LRERGIQVKDAGQFGLHH----IRISIG---REEDNDRLLAALAEYSDH.. 336
53 -17.2004wxb_A mol:protein length:428 Serine hydroxymethyltransferase  ali model follow..  14  3..............GSGSMIFDKEDYKAFDPELWNAIDAEAERQQNNIELIASENVVS----KAVMAAQGTLLNKYAEGYPGKRYYGGTAVVETLAIERAKKLFGAKFANV--SGSQANAAVYMSLIQ--PGDTVMGSAGGHLTHGAPVSFSGKTYNFVSYNDYDAILAQAKE---VRPKLIVAGA--SAYSRIIDFAKFREIADAVGAYLMVDMAHIAGLVASG-----HHPSPVPYAHVTTTTTHKTLGPRGGLILTDDEDIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDPAFKEYGENVIKNAAAMADVFNQHPDFRGGTNNHLFLVDVTKVVENGKVAQNVLEEVNITLNKNSIPYEQLSTSGIRVGSPAI-GEAESRQIAEWMVEALEN.. 398
54 -17.1001elq_A mol:protein length:390 L-CYSTEINE/L-CYSTINE C-S LYASE  ali model follow..  13  9.............................................HQFPGLANKTYFNFGGQGILPTVALEAITAMENGPFSIAANQHIQQLIAQLRQALAETFNVDNTITITDNVTTGCDIVLWGLDWHQGDEILLTDCEHPGIIFGITYRFFPVA--ATLNQGDAAAVLANHLGPKTRLVILSHLLWNTGQVLPLAEIMAVCRRHQGRVLVDGAQSAGSLPLDFSRL--------EVDYYAFTGHKWFGPAGGGLYIHGDCLGEINPTYVGW-FEVATSAPQYAGLLAALQLHQR--AEERYQAICQRSEFLWRGLNQLPLATSAPQAGLVSFTV-DSPLGHRAIVQKLEEQRIYLRTIADPDC------IRACCHYITDEEEINHLLARLADF..... 388
55 -17.1003cq4_A mol:protein length:376 Histidinol-phosphate aminotransferase  ali model follow..  15  27.............................................NVDIRLNTNE---YPPSEALVADLVATVDKIATELN--------ERDAVELRDELAAYITKQTGLWAANGSNEILQQL-LQAFGGPGRTALGFQPSYSMHPILAKGTHTEFIAVSRGA--DMDVALEEIRAKQPDIVFVTTPNNPTGDVTSLDDVERIINVAPGIVIVDEAYA-----SPSPSATTLLEKYPTKLVVSRTMSKAFDFAGGYFVANPAFIDAVMLVRLPY----HLSALSQAAAIVALR--HSADTLGTVEKLSVERVRVAARLEELGYAVVPSESNF--VFFGDFSDQHAAWQAFL-DRGVLIRDVGIAG-------LRTTIG---VPEENDAFLDAAAEIIKL.. 364
56 -17.1004n0w_A mol:protein length:424 Serine hydroxymethyltransferase  ali model follow..  18  10.......................STIANVDPEIFAAIEQENRRQEDHIELIASENYTS----PAVMAAQGSQLNKYAEGYPGKRYYGGCEVVEQLAIDRVKQLFGAEAANV--SGSQANQGVFFAMLKPGDTIMGMSAHGGHLTHGSPVNMSGKWFNVVSYGDYDAAEKLANE---HKPKLIVAGA--SAFALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAG-----VYPNPVPHADFVTTTTHKSLGPRGGVILMKAEYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSPE-FKEYQQKVVENARVLAETLVKRGLRIGRTESHVMLVDLRAKHITGKAAEAALGAAHITVNKNAIPNDPEKTSGIRLGSPAM-GPAEAEQVGNLIADVLEN.. 393
57 -17.1001yiy_A mol:protein length:429 kynurenine aminotransferase; glutamine transaminase K  ali model follow..  13  1..........MSSTSNETMHNKFDLPKRYQGSTKSVWVEYIQLAAQYKPLNLGQGFPDYHAPKYALNALAAAANSPDPLANQYTRGFGHPRLVQALSKLYSQLVDRTTEVLVTVG--AYEALYATIGHVDEGDEVIIIEPFFDCYEPMVKAAGGIPRFIPSADWVLDNNELEALFNEKTKMIIINTPHNPLGKVAELEVVANLCKKWNVLCVSDEVYEHMVFEPFEHIRICTLPGMWERTITIGSAGKTFSLTGGWAYGPEALLKNLQMVHQNCVYTCATP-AIAVGFETELKRLKSPECNSISGELMAKRDYMASFLAEVGMNPTVPQGGYFMVA-TDARKDYRFTKWMTKSVGLQGIP-SEPNKHLGEDFVRYCFFK--KDENLQKAAEILRKWKGS.. 428
58 -17.1005uts_G mol:protein length:501 C-S Lyase Egt2  ali model follow..  14  51......................................................NHGSFGTIPSAIQQKLRSYQTAAEARPCPFLRYQTPVLLDESRAAVANLLKVPETVVFVANATMGVNTVLR--SADGKDEILYFDTIYGACGKTIKRGIVSSRCIPLIYPAEDDDVVAREEGKRPRLAVIDVVSSMPGVRFPFEDIVKICKEEEIISCVDGAQGIGMVDLKITET--------DPDFLISNCHKLFTPRGAVFYVPVRNQHLIRAFVSNFEFVGTVDNSPFFCVKDAIKWREEVLGERIMEYMTKLAREGGQKVAEIGTRVLENSTG-LPFVVGEDPKAPWMYNVLQDEFNTFVPMTFH----RRRFWARLSAQVYLEMSDFEWAGKTLKELCERVA 472
59 -17.1003ecd_A mol:protein length:425 Serine hydroxymethyltransferase 2  ali model follow..  15  11.......................QSLAERDASVRGAILKELERQQSQVELIASENIVS----RAVLDAQGSVLNKYAEGYPGKRYYGGCEEVEALAIERVKRLFNAGHANV--SGAQANGAVMLALAK--PGDTVLGDAGGHLTHGAKPALSGKWFNALQYGDYDQVEALAQQ---HKPSLIIAGF--SAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAG-----RHANPVEHAHVVTSTTHKTLGPRGGFVLTNDEEIAKKINSAVFPGLQGGPLMHVIAGKAVAFGEALTDDFKTYIDRVLANAQALGDVLKAGGVDLGGTDNHLLLVDLRPKGLKGAQVEQALERAGITCNKNGIPFDPEKTSGIRLGTPAG-GAAEFREVGRLILEVFEA.. 396
60 -17.1002c44_A mol:protein length:471 TRYPTOPHANASE  ali model follow..  14  26...........................................YREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVTQSMQAAMMRGDEAY-YALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKYFFDTTQGHSQINGCTVTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGSLANLKAMYSIAKKYDIPVVMDSAENAYFIKQREAEYKDW-ETYKYADMLAMSAKKDAMVMGGLLCMKDDSFFDVYTECRTLCVVQE---LEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVIPADQFPAQALACELYKVAGIRAVEI---QLPCPAELLRLTIRATYTQTHMDFIIEAFKHVKEN.. 445
61 -17.0004r8d_A mol:protein length:394 Histidinol-phosphate aminotransferase  ali model follow..  13  32.............................................AVPVRLNTNE---HPPTRALVDDVVRSVRE-----AAIDLHRYPDRDAVALRADLAGYLTAQTGIWAANGSNEILQQL-LQAFGGPGRSAIGFVPSYSMHPIISDGTHTEWIEASRAN--DVDVAVAAVVDRKPDVVFIASPNNPSGQSVSLPDLCKLLDVAPGIAIVDEAYG-----SSQPSAVSLVEEYPSKLVVTRTMSKAFAFAGGYLIATPAVIDAMLLVRLPY----HLSSVTQAAARAALR--HSDDTLSSVAALIAERERVTTSLNDMGFRVIPSDANF--VLFGEFADAPAAWRRYL-EAGILIRDVGIPGY------LRATTG---LAEENDAFLRASARIATDLV 371
62 -16.9001ax4_A mol:protein length:467 TRYPTOPHANASE  ali model follow..  16  24...........................................EREAALKEAGYNPFLLPSSAVYIDLLTDSGTNAMSDHQWAAMITGDEAYYYDLKDKAKELFNYDYIIPAHQGRGAENILFPVLLKYKQKEGVFISNFHFDTTAAHVELNGCKAINIVTEDIKKLKENIAQHGADNIVAIVSTVTCNSAGSMSNLKEVYEIAKQHGIFVVMDSAENAYFIKARDPKYKNA-DMYKYADALTMSAKKDPLLIGGLVADNEEIFTLARQRCVPMEGFVTYGGLAGRDMAAMVQGLEEGTEEEYLHYRIGQVKYLGDRLREAGIPIQYDCKKLVPQIPGDQFPAQAVINALYLESGVRADPATGEQKHADMEFMRLTIRRVYTNDHMDYIADALIGLKEK.. 440
63 -16.9003bs8_A mol:protein length:438 Glutamate-1-semialdehyde 2,1-aminomutase  ali model follow..  16  45...........................................KGSKIFDIDGNEYIDYVTNDRVVESLKKVAEY-GTSFGAP------TEVENELAKLVIDVPSVEIVRMVSSGTEATMSALRLARGYTGRNKILKFEGCYHGHGDSLLIKAGSTITVPYNDLESVKLAFQQFGEDIAGVIV-EPVAGNMGVVPPLQGLRDITEQYGSLLIFDEV--TGFRVDYN-CAQGYFGVTPDL----TCLGKVIG--GGLYGGKAEIMEQIAPSGPIYQAGTSGNPLAMTAGLETLKQLTPDSYKNFIKKGDRLEEGISKAAEAHGIPHFNRAGSMIGFFFTNDLKLFASYYKGMANEGVFLPP---------SQFEGLFLSTAHTDEDIENTIQAAEKVFAEIS 430
64 -16.9004j5u_A mol:protein length:420 Serine hydroxymethyltransferase  ali model follow..  17  6.......................NNLHETDKEINEIIKHEKLRQSSVIELIASENFVS----PAVLEAQGALLNKYAEGYPSKRFYNGCEKAENLAIERVKKLFNCKYANV--SGSQANQAVYLALLQ--PGDTVLGDSGGHLTHGAAPNMSGKWFNAVSYSDYDEIERLADL---HKPKLLIAGF--SAYPRNIDFAKFREIVDKVGAYFMADIAHIAGLVATG-----EHQSPIPYAHAVTSTTHKTLGPRGGLILSNDEEIGHKINSALFPGLQGGPLMHIIAAKAVAFLENLQPEYKSYIQQVISNAKALASSLQERGYDILTGGTHIVLVDLRKDGITGKLAANSLDRAGITCNKNAIPFDETSTSGIRLGTPAC-KEKDFVLVGHMVADILDG.. 391
65 -16.9001dfo_A mol:protein length:417 SERINE HYDROXYMETHYLTRANSFERASE  ali model follow..  17  1..................MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTS----PRVMQAQGSQLNKYAEGYPGKRYYGGCEIVEQLAIDRAKELFGADYANV--SGSQANFAVYTALLE--PGDTVLGAHGGHLTHGSPVNFSGKLYNIVPYGDYADLEKQAKE---HKPKMIIGGF--SAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAG-----VYPNPVPHAHVVTTTTHKTLGPRGGLILAKGGSEELYKKLNSAVFGQGGPLMHVIAGKAVALKEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTHLFLVDLVDKNLTGKEADAALGRANITVNKNSVPNDPKSTSGIRVGTPAI-KEAEAKELAGWMCDVLDS.. 392
66 -16.9004oyt_A mol:protein length:442 Serine hydroxymethyltransferase, putative  ali model follow..  10  5.......................EPLEQIDKELHDILADEEKRQRETINLIASENLTN----GAVRECLGNRVNKYSEGYPKKRYYGGNDKIEELCQKRALEAFNVSDEEWGVSGSAANVQALYALVGVKGKIMGMHLC-GHLTHGFFDEKKKVSITSDMFEDLDAVREMALS---FKPKVIICGY--TSYPRDIDYQQFRQICDEVNAYLFADISHISSFVACN-----ILNNPFLHADVVTTTTHKILGPRSALIFFNKKRNPGIEQKINSAVFPSFQG-NKIAAVACQLKEVHSPAFKEYTQQVLLNSKALAKALISKQIDLNGTDNHLIVVDLRKFSITGSKLQETCNAINVSLNKNTIPSDVDSPSGVRIGTPAM-KEKDMEFIADVLARAIK... 399
67 -16.9001jf9_A mol:protein length:408 SELENOCYSTEINE LYASE  ali model follow..  15  28.......................................................YLDSAASAQKPSQVIDAEAEFAVHRGIHTLSAQATEKMENVRKRASLFINARSALVFVRGTTEGINLVAGNSNVRAGDNIIISQMEHHANIVGAELRVIPLNPDGTLQLETLPTLFDE----KTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMLYGPTGIGIL-KEALLQEMPPWEG---------GGSMIATVSLSEGTTWTKAPWRFEAGTPNGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLESVDLTLYGPQNRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMP--PAMCRASLAMYNTHEEVDRLVTGLQRIHRLLG 408
68 -16.8004o6z_A mol:protein length:480 Serine hydroxymethyltransferase  ali model follow..  10  37.......................DPLQKYDKELFDLLEKEKNRQIETINLIASENLTN----TAVRECLGDRINKYSEGYPHKRYYGGNDKIEELCYKRALEAFNVSEEEWGVSGSAANVQALYALVGVKGKIMGMHLC-GHLTHGFFDEKKKVSITSDLFEDMESVRNLALS---FQPKVIICGYTSYP-----DYKGFREICDEVNAYLFADISHISSFVACN-----LLNNPFTYADVVTTTTHKILGPRSALIFFNKKRNPGIDQKINSSVFQGGPHNNKIAAVACQLKEVNTPEFKEYTKQVLLNSKALAECLLKRNLDLNGTDNHLIVVDLRKYNITGSKLQETCNAINIALNKNTIPSDVDSPSGIRIGTPAL-KEKDMEFIADMLLKAIL... 431
69 -16.8001c0n_A mol:protein length:406 PROTEIN (CSDB PROTEIN)  ali model follow..  16  26.......................................................YLDSAASAQKPSQVIDAEAEFAVHAGAHTLSAQATEKMENVRKRASLFINARSALVFVRGTTEGINLVAGNSNVRAGDNIIISQMEHHANIVGAELRVIPLNPDGTLQLETLPTLFDA----ATRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMLYGPTGIGIL-KEALLQEMPPWEG---------GGSMIATVSLSEGTTWTKAPWRFEAGTPNGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLESVDLTLYGPQARLGVIAFNLGAHHAYDVGSFLDNYGIAVRTGHHCAMP--PAMCRASLAMYNTHEEVDRLVTGLQRIHRLLG 406
70 -16.8003k28_A mol:protein length:429 Glutamate-1-semialdehyde 2,1-aminomutase 2  ali model follow..  17  43...........................................KGSKVYDIDGNEYIDYVANDRVVEALKAVAER-GTSFGAP------TEIENKLAKLVIEVPSIEIVRMVNSGTEATMSALRLARGYTGRNKILKFIGCYHGHGDSLLIKAGNTITVAYNDLESVKYAFEQFGDDIACVIV-EPVAGNMGVVPPLEGLREVTEQNGALLIFDEV--TGFRVAYN-CGQGYYGVTPDL----TCLGKVIG--GGLYGGKAEIMRQVAPSGPIYQAGTSGNPLAMAAGYETLVQLTPESYVEFERKAEMLEAGLRKAAEKHGIPHINRAGSMIGIFFTDNLQFFAAYYREMVEQGVFLPP---------SQFEGLFLSTVHSDADIEATIAAAEIAMSKLK 428
71 -16.8002dkj_A mol:protein length:407 serine hydroxymethyltransferase  ali model follow..  16  1......................MVSTLKRDEALFELIALEEKRQREGLELIASENFVS----KQVREAVGSVLNKYAEGYPGARYYGGCERVESLAIERAKALFGAAWANV--SGSQANMAVYMALME--PGDTLMGAAGGHLTHGSRVNFSGKLYKVVSYGDLEEVRRLALE---HRPKVIVAGA--SAYPRFWDFKAFREIADEVGAYLVVDMAHFAGLVAAG-----LHPNPLPYAHVVTSTTHKTLGPRGGLILSNDPELGKRIDKLIFPGIQGGPLEHVIAGKAVAFFEALQPEFKEYSRLVVENAKRLAEELARRGYRIVTGGTHLFLVDLRPKGLTGKEAEERLDAVGITVNKNAIPFDPKPTSGIRIGTPAI-TPEEMPLVAELIDRALLE.. 387
72 -16.8002dou_A mol:protein length:376 probable N-succinyldiaminopimelate aminotransferase  ali model follow..  11  3.......................RVPEPSVFLVVDEAKRKARERGVGLIDLSIGS--DLPPPEAPLKALAEALND--PTTYGYCLKSCTLPFLEEAARWYEGRYGVRREALALIGSQEGLAHL-LLALTEPEDLLLLPEVAYPSYFGAARVASLRTFLIPLREDGLADKAVPEGVWREAKVLLLNYPNNPTGAVADFEEALGLARKHGLWLIHDNPYVDQVYEGEAPSPLALPGAKERV-VELFSLSKSYNLAGGFALGSEEALARLERVKGVI--DFNQYAGVLRMGVEALK--PKEVVRGYARVYRERALGMAEALKGVLSLLPPRATMYLWGRLPEGVDDLEFGLRLVERGVALAPGRGFGPGGKGFVRIALVRPLEELLEAAKRIREALD....... 376
73 -16.8004nog_A mol:protein length:442 Putative ornithine aminotransferase, mitochondrial  ali model follow..  15  45...........................................KGARVWDINGNEYYDFLAHPRVIAALCRQAERLTLTLRA------GNDVTGPACRFMAEMFGYDRVLLMNTGAEAGESALKIARKWASAKVILCNNNYWGRTITACSSSTTFDCYFELIDYDDVGALEEALKDPNVAAFFVEPIQGEGGVNVPLKRAHELCRSKNVLLIVDEIQT---LCRTGR-AADHDEVHPDI-----LLGKSLSA--SAVMGRADVMDVLKPGTHGSTFGGN--PLACAVAVEALTVLKDEK---LADRAERLGAQFRDCLRRE-IKEIRGRGLLNAVEVDSDAIDPNDVVMKLKENGILS-------KPTRGRVMRFIPPLVITDEEHRDATTRIIKSFLAVE 421
74 -16.6005vc2_A mol:protein length:424 Serine hydroxymethyltransferase  ali model follow..  16  5.......................YFLEQTDSEIFELIFEEYKRQNEHLEMIASENYTF----PSVMEAMGSILNKYAEGYPNKRYYGGCEKIESLAIERAKKLFNCQFANV--SGSQANNAVYHALLKPYDKILGMDLS-GHLTHGAKVSLTGKHYQSFSYGDYEEALKIAQS---VKPEIIVCGF--SAYPREIDFKKFREIADEVGALLLGDIAHVAGLVVTN-----EHAHPFPHCHVVSSTTHKTLGPRGGIILTNDEEIAAKIDKAIFPGTQGGPLMHVIAAKAVGFKENLKPEFKAYAKLVKSNMQVLAKALKEKNHKLVSGGTHLLLMDFLDKPYSGKDADIALGNAGITVNKNTIPGETRSTSGIRIGSAAL-GAKEFEIIGNKISDILND.. 389
75 -16.6001o4s_A mol:protein length:389 Aspartate aminotransferase  ali model follow..  12  2............GSDKIMVSRRISEIPISKTMELDAKAKALIKKGEDVINLTAGE--DFPTPEPVVEEAVRFLQK---GEVKYTDPRGIYELREGIAKRIGERYKKDDQVVVTNG--AKQALFNAFALLDPGDEVIVFSPVWVSYIPQIILAGGTVNVVETFMSKNFQEEVEGLLVGKTKAVLINSPNNPTGVVEFLEGLVRLAKKRNFYIISDEVYDSLVYTDEFTSILDVSEGFDRI-VYINGFSKSHSMTGGYLISSEKVATAVSKIQSHT--TSCINTVAQYAALKALE----VDNSYMVQTFKERKNFVVERLKKMGVKFVEPEGAFY-LFFKVRGDDVKFCERLLEEKKV---ALVPGSAFLKPGFVRLSFAT--SIERLTEALDRIEDFLNS.. 382

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Jaroszewski L, Godzik A. Sequence clustering strategies improve remote homology recognitions while reducing search times. Protein Eng. 2002 Aug;15(8):643-9.