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Query: 2eiv_A mol:protein length:291 Arginase, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MERVAVVGVPMDLGANRRGVDMGPSALRYARLLEQLEDLGYTVEDLGDVPVSLARASRRRGRGLAYLEEIRAAALVLKERLAALPEGVFPIVLGGDHSLSMGSVAGAARGRRVGVVWVDAHADFNTPETSPSGNVHGMPLAVLSGLGHPRLTEVFRAVDPKDVVLVGVRSLDPGEKRLLKEAGVRVYTMHEVDRLGVARIAEEVLKHLQGLPLHVSLDADVLDPTLAPGVGTPVPGGLTYREAHLLMEILAESGRVQSLDLVEVNPILDERNRTAEMLVGLALSLLGKRIFLast
1 -98.6002eiv_A mol:protein length:291 Arginase  ali model  100  1MERVAVVGVPMDLGANRRGVDMGPSALRYARLLEQLEDLGYTVEDLGDVPVSLARASRRRGRGLAYLEEIRAAALVLKERLAALPEGVFPIVLGGDHSLSMGSVAGAARGRRVGVVWVDAHADFNTPETSPSGNVHGMPLAVLSGLGHPRLTEVFRAVDPKDVVLVGVRSLDPGEKRLLKEAGVRVYTMHEVDRLGVARIAEEVLKHLQGLPLHVSLDADVLDPTLAPGVGTPVPGGLTYREAHLLMEILAESGRVQSLDLVEVNPILDERNRTAEMLVGLALSLLGKRIF 291
2 -86.7001pq3_A mol:protein length:306 Arginase II, mitochondrial precursor  ali model follow..  36  1.HSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSSLGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVLANQELAEVVSRAVSDGYSCVTLGGDHSLAIGTISGHARCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQLATSEEEAKTTANLAVDVIASSF. 300
3 -86.1001wva_A mol:protein length:322 Arginase 1  ali model follow..  37  6.RTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACF. 304
4 -85.6001t5f_A mol:protein length:314 Arginase 1  ali model follow..  36  1.KPIEIIGAPFSKGCPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARHPDLAVIWVDAHTDINTPLTTSSGNLAGQPVAFLLKELKGKFPDVTPAISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSAF. 299
5 -85.4001d3v_A mol:protein length:323 PROTEIN (ARGINASE)  ali model follow..  36  6.KPIEIIGAPFSKGQPRGGVEKGPAALRKAGLVEKLKETEYNVRDHGDLAFVDVPNDSPFQIVKNPRSVGKANEQLAAVVAETQKNGTISVVLGGDHSMAIGSISGHARHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPTLGKTPEEVTRTVNTAVALTLSCF. 304
6 -84.7001cev_A mol:protein length:299 PROTEIN (ARGINASE)  ali model follow..  53  1MKPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERLHYDIEDLGDIPIGKAERLHEQGDLRNLKAVAEANEKLAAAVDQVVQRGRFPLVLGGDHSIAIGTLAGVAKYERLGVIWYDAHGDVNTAETSPSGNIHGMPLAASLGFGHPALTQISPKIKPEHVVLIGVRSLDEGEKKFIREKGIKIYTMHEVDRLGMTRVMEETIAYLKEDGVHLSLDLDGLDPSDAPGVGTPVIGGLTYRESHLAMEMLAEAQIITSAEFVEVNPILDERNKTASVAVALMGSLFGEKLM 299
7 -84.2006dkt_A mol:protein length:296 Arginase  ali model follow..  50  3.KTISVIGMPMDLGQARRGVDMGPSAIRYAHLIERLSDMGYTVEDLGDIPINREKIKND-EELKNLNSVLAGNEKLAQKVNKVIEEKKFPLVLGGDHSIAIGTLAGTAKYDNLGVIWYDAHGDLNTLETSPSGNIHGMPLAVSLGIGHESLVNLAPKIKPENVVIIGARSLDEGERKYIKESGMKVYTMHEIDRLGMTKVIEETLDYLSADGVHLSLDLDGLDPNDAPGVGTPVVGGISYRESHLAMEMLYDAGIITSAEFVEVNPILDHKNKTGKTAVELVESLLGKKLL 296
8 -81.4005ynl_A mol:protein length:362 Arginase  ali model follow..  35  50.RTAGIVGCPFSGGQPKAGVHSGPLQLIESGLLNDIENLGWTVDFAGADALAVSIVSDTPDPDIGRLKQPRLVKDVADRVYAHASKGQLTVTLGGDHSLAMGTVSGTFKYPEACLIWVDAHADINTPHTTESGRLHGCPVSFLLGLDGPEFSWIKPCLKPERIVYIGLRDIDAGERKILKDNNIKCFSMFHVDKYGIGKVVEMALDHVRTRPIHLSFDVDALDPSVAPSTGTAVRGGLTFREGHYICEAIAETNLLVSLDIMEINPSLGALAQTVDVGRSLVRCALGETLL 356
9 -77.2004ity_A mol:protein length:330 Arginase  ali model follow..  32  8.KKMSIVLAPFSGGQPHSGVELGPDYLLKQGLQQDMEKLGWDTRLERVFDGKVVEARKASDRVKRPRLTAECTEKIYKCVRRVAEQGRFPLTIGGDHSIALGTVAGVLSHPDAGVIWVDAHADINTMSGTVSGNLHGCPLSILLGLDRENIPECFQVLKPNKIAYIGLRAVDDEEKKILHDLNIAAFSMHHVDRYGIDKVVSMAIEAVGTEPVMVSYDVDTIDPLYVPATGTPVRGGLSFREALFLCERIAECGRLVALDVVECNPLLAATESHVNDTISVGCAIARCMM. 310
10 -74.4004q3p_A mol:protein length:385 Arginase  ali model follow..  29  37.TSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAESLTTLRIAERVEELMKQSNKHTVELSGSKSTPVIVGGDHSMATGTILGHAEKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEKTQSSAVHILRACLGHC.. 351
11 -73.4003nip_A mol:protein length:326 3-guanidinopropionase  ali model follow..  30  36..QVGLIGVPWDGGTTRAGARHGPREVRNLSSLMRKVHHVVRVGDLGDAPVNPIDLL-------------DSLRRIEGFYRQVHAAGTLPLSVGGDHLVTLPIFRALGRERPLGMVHFDAHSDTNDRYFGDNPYTHGTPFRRAIEEG---------LLDPLRTVQIGIRGSSPDDDAFARECGIRVIHMEEFVELGVEATLAEARRVVGAGPTYVSFDVDVLDPAFAPGTGTPEIGGMTSLQAQQLVRGL-RGLDLVGADVVEVSPPFDVGGATALVGATMMFELLCLLA. 311
12 -72.8004g3h_A mol:protein length:330 Arginase (RocF)  ali model follow..  20  1...MILVGLEAELGASKRGTDKGVRRLREALSATHGDV----IKGMQTITQERCVLYKEFRYAKNFEDYYLFCENLIPCMKEVFEKKEFPLILSSEHANMFGIFQAFRSVKKIGILYLDAHADIHTAYDSDSKHIHGMPLGMVLNRVRSGFNRMGLEIDPKCLVYFGVRSTEQSERDVIRELQIPLFSVDAIRE-NMQEVVQKTKESLKADIIYLSLDLDIMDGKLFTSTGVRENNGLSFDELKQLLGLLLESDRLKAVEVTEYNPTVSIKHNNEKQVLEILDLIINSCK. 310
13 -70.8001wog_A mol:protein length:305 agmatinase  ali model follow..  27  30..DVAALGVPFDIALGRPGARFAPRALREASLRSVPPFQGVTFADAGDVILPSLEPQ-------------LAHDRITEAARQVRGRCRVPVFLGGDHSVSYPLLRAFADVPDLHVVQLDAHLDFTDTR-NDTKWSNSSPFRRACEAL----------PNLVHITTVGLRGLDPEAVAAARARGHTIIPMDDVTADL----AGVLAQLPRGQNVYFSVDVDGFDPAVIPGTSSPEPDGLTYAQGMKILAAAAANNTVVGLDLVELAPNLDPTGRSELLMARLVMETLCEVF. 301
14 -70.5003nio_A mol:protein length:319 Guanidinobutyrase  ali model follow..  28  39..DAAFVGVPLDIGTSRSGTRFGPREIRAESVMIRPYNMSLNVADIGDVAINTFNLL-------------EAVRIIEQEYDRILGHGILPLTLGGDHTITLPILRAIKKHGKVGLVHVDAHADVNDHM-FGEKIAHGTTFRRAVEED---------LLDCDRVVQIGLRAQTAEDFNWSRKQGFRVVQAEECWHKSLEPLMAEVREKVGGGPVYLSFDIDGIDPAWAPGTGTPEIGGLTTIQAMEIIRGC-QGLDLIGCDLVEVSPPYDTTGNTSLLGANLLYEMLCVLP. 314
15 -70.1001gq6_A mol:protein length:313 PROCLAVAMINATE AMIDINO HYDROLASE  ali model follow..  28  31..DVVVIGAPYDGGTSRPGARFGPQAIRSESGLIHGVGIDINCVDAGDINLTPFDMN-------------IAIDTAQSHLSGLLKANAAFLMIGGDHSLTVAALRAVAEHGPLAVVHLDAHSDTNPAF-YGGRYHHGTPFRHGIDEK---------LIDPAAMVQIGIRGHKPDSLDYARGHGVRVVTADEFGELGVGGTADLIREKVGQRPVYVSVDIDVVDPAFAPGTGTPAPGGLLSREVLALLRCV-GDLKPVGFDVMEVSPLYDHGGITSILATEIGAELLYQYA. 306
16 -69.5004dz4_A mol:protein length:324 Agmatinase  ali model follow..  28  48..DVVVSGVPLDLATTRSGARLGPSAVRAASVQLAELNDDLAVIDYGDCWFDAHHPL-------------SIKPAIVEHARTILQSDARMLTLGGDHYITYPLLIAHAQKKPLSLIHFDAHCDTWADD-APDSLNHGTMFYKAVKDG---------LIDPKASVQVGIRTWNDDY------LGINVLDAAWVHEHGARATLERIESIVGGRPAYLTFDIDCLDPAFAPGTGTPVAGGLSSAQALAIVRGL-GGVNLIGADVVEVAPAYDQSEITAIAAAHVACDLLCLWR. 317
17 -69.3003lhl_A mol:protein length:287 Putative agmatinase  ali model follow..  22  9..NLIVFGVGFDGTTSRPGARFASSSMRKEFYGLETYSPDYNICDYGDLEISVGSTE-------------QVLKEIYQETYKIVRDSKVPFMIGGEHLVTLPAFKAVHEYNDIYVIHFDAHTDLREEY-NNSKNSHATVIKRIWDI-----------VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGID------TFENIVNMLNGKNIYLTIDLDVLDASVFPGTGTPEPGGVNYREFQEIFKIIKSNINIVGCDIVELSPDYDTTGVSTVIACKILRELCLIIS. 275
18 -68.9003m1r_A mol:protein length:322 Formimidoylglutamase  ali model follow..  23  39..GPALIGVPLSKSSIHSGASFAPGTIRQALKHSSAYSAELGLYDLGDIDIHVTDIVKSHHHIFQTMHALLSD-----------HPDWVPLILGGDNSISYSTIKAIAQKGTTAVIQFDAHHDVRNTE--DGGPTNGTPFRRLLDEE---------IIEGQHLIQLGIREFSQAYEAYAKKHNVNIHTMDMIREKGLIPTIKEILPVVQDDFIFISVDMDVLDQSHAPGCPAIGPGGLYTDELLEAVKYIAQQPNVAGIEIVEVDPTLDFRDMTSRAAAHVLLHALKGMKL 318
19 -68.6003mmr_A mol:protein length:413 Arginase  ali model follow..  33  18.KNVSIIGSPLAAGQPLGGVQLACDDLRKLGLHNVIDVLGWKYEDIGNIDNGDNENNCYYDNIRNIKEIGIFSKNLFDTMSNELRKKNFVLNIGGDHGVAFSSILSSLQYQNLRVIWIDAHGDINIPETSPSGNYHGMTLAHTLGLFKKKVPYFLTYLKPENTAIIGIRDIDAYEKIILKKCNINYYTIFDIEKNGIYNTICTALEKISNCPIHISLDIDSVDNVFAPGTGTVAKGGLNYREINLLMKILAETKRVVSMDLVEYNPSLDEVDKKVKLCLELIARVLGYDIV 407
20 -66.9003pzl_A mol:protein length:313 Agmatine ureohydrolase  ali model follow..  27  36..KYVVFGIPFDNTSSRRGSKYAPDSIRGAYVNLESYEYASGMADLGDMEESE--------------DVEYVIDTVESVVSAVMSDGKIPIMLGGEHSITVGAVRALPK--DVDLVIVDAHSDFRSSY-MGNKYNHACVTRRALDL-----------LGEGRITSIGIRSVSREEFEDPDFRKVSFISSFDVKKNGIDKYIEEVDR--KSRRVYISVDMDGIDPAYAPAVGTPEPFGLADTDVRRLIERLSY--KAVGFDIVEFSPLYD-NGNTSMLAAKLLQVFIASRE. 298
21 -65.1004rhm_A mol:protein length:351 Arginase  ali model follow..  23  17..SKFLMNVKGVTPRGDWANRLGPVALFGYGAGMPRRAAELTIHDKGPIECPPETVMFMPVLNCGQMLDEEWYLGSLEASTELLEKGYVPVSVGGDGSATLSMVEAYKRSDDIVIVHFDAHPDVSD---------PRSPLRVLLDKGLL-----------KGVVSVGNRQVSSEDRKVRKLHKMFYMDMHAIYSKG----LFCIRDIRNDYPVFISIDADVLDPAFAPAVDSPVAGGLSTRDLLHIMNGI-RGPKVVGIDVYGYNPDLDNVGLTAIALSKIIKEGILKAY. 314
22 -64.8002a0m_A mol:protein length:316 ARGINASE SUPERFAMILY PROTEIN  ali model follow..  21  25..DIVIIGFPYDEGCVRAGAKKGPAAFRFFLQRLGSVNSHLKLYDAGDITASTLE---------------EAHEKLESKVFTVLARGAFPFVIGGGNDQSAPNGRAMLRAGDVGVINVDSHLDVRPPL-QDGRVHSGTPFRQLLEES---------SFSGKRFVEFACQGSGALHAQYVRDHQGHLMWLSEVRKKGAVAALEDAFGLTGK-NTFFSFDVDSLKSSDMPGVSCPAAVGLSAQEAFDMCFLAGKTPTVMMMDMSELNPLVE-EYRSPRVAVYMFYHFVL.... 298
23 -63.2004rhi_A mol:protein length:351 Arginase  ali model follow..  22  24...KGVTPRGSD-----WANRLGPVALFGYGAGMPRRAAELTIHDKGPIECPPETVMFMPVLNCGQMLDEEWYLGSLEASTELLEKGYVPVSVGGDGSATLSMVEAYKRSDDIVIVHFSARPSVSD---------PRSPLRVLLDKGLL-----------KGVVSVGNRQVSSEDRKVRKLHKMFYMDMHAIYSKG----LFCIRDIRNDYPVFISIDASVLDPAFAPAVDSPVAGGLSTRDLLHIMNGI-RGPKVVGIDVYGYNPDLDNVGLTAIALSKIIKEGILKAY. 314
24 -57.8001xfk_A mol:protein length:336 Formimidoylglutamase  ali model follow..  19  44..GVALIGFECDAGVGRTGAKHAPSLIKQALANLAWHH-PIPIYDLGNIRCEGDE--------------LEQAQQECAQVIQQALPHARAIVLGGGHEIAWATFQGLAQHPRIGIINFDAHFDLRTFESELAPVSSGTPFNQIHHFCQQQ--------WDFHYACLGVSRATPALFERADKLGVWYVEDKAFSPLSLKDHLTQLQHFIDDDYLYLTIDLDVFPAASAPGVSAPAARGVSLEALAPYFDRILHKNKLMIADIAEYNPSFDIDQHTARLAARLCWDIANAMA. 327
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.