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Query: 3can_A mol:protein length:182 Pyruvate-formate lyase-activating enzyme, from PDB1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst SNAGGGVTFCGGEPLLHPEFLIDILKRCGQQGIHRAVDTTLLARKETVDEVMRNCELLLIDLKSMDSTVHQTFCDVPNELILKNIRRVAEADFPYYIRIPLIEGVNADEKNIKLSAEFLASLPRHPEIINLLPYHDIGKGKHAKLGSIYNPKGYKMQTPSEEVQQQCIQILTDYGLKATIGGLast
1 -96.1003can_A mol:protein length:182 Pyruvate-formate lyase-activating enzyme  ali model  100  1SNAGGGVTFCGGEPLLHPEFLIDILKRCGQQGIHRAVDTTLLARKETVDEVMRNCELLLIDLKSMDSTVHQTFCDVPNELILKNIRRVAEADFPYYIRIPLIEGVNADEKNIKLSAEFLASLPRHPEIINLLPYHDIGKGKHAKLGSIYNPKGYKMQTPSEEVQQQCIQILTDYGLKATIGG 182
2 -73.6003c8f_A mol:protein length:245 Pyruvate formate-lyase 1-activating enzyme  ali model follow..  31  67NASGGGVTASGGEAILQAEFVRDWFRACKKEGIHTCLDTNGFVRRPVIDELLEVTDLVMLDLKQMNDEIHQNLVGVSNHRTLEFAKYLANKNVKVWIRYVVVPGWSDDDDSAHRLGEFTRDM-GNVEKIELLPYHELGKHKWVAMGEEYKLD--GVKPPKKETMERVKGILEQYGHKVMF.. 245
3 -20.1002yx0_A mol:protein length:342 radical sam enzyme  ali model follow..  11  146......AISLSGEPMLYPY-MGDLVEEFHKRGFTTFIVTNGTIRLEEMIKEDKLPTQLYVSITAPDIETYNSVNIPMIERILRFLELMRDLPTRTVVRLTLVKGENM--HSPEKYAKLILKARPMFVEAKAYMFVGYSRNRLTINNMPSHQDIREFAEALVKHLPGYHIEDEYEPSRVVL.. 322
4 -19.2004njg_A mol:protein length:230 7-carboxy-7-deazaguanine synthase  ali model follow..  16  95GEAHRFVVCTGGEPMLQLDQ--PLVDALHAAGFGIAIETNGSLP------VLESIDWICVSPKADAPLVVTKGNELKVVIPQDNQRLADYAKLDFEYFLVQPMDGPSRDLNTKLAIDWCKRH----PQWRLSMTHKY............................................. 220
5 -19.1006djt_A mol:protein length:331 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase  ali model follow..  19  146......AISLSGEPTLYPYLD-ELIKIFHKNGFTTFVVSNGILTDVIEKIEP---TQLYISLDAYDLDSYRRICGGKKESILNTLDILKEKKRTC-IRTTLIRGYNDDILKFVELYERA-----DVHFIELKSYMHVGYSQKRL--------KKEDMLQHDEILKLAKMLDENSSYKLI... 303
6 -16.8005v1q_A mol:protein length:459 Radical SAM  ali model follow..  16  169......VSILGGEPTRYFDID-NLLIACEELKIKTTITTNAQLIKKSTVEILAKSKYPVLSLQTLDSKLNFELMGVRPDRQIKLAKYFNEVGKKCRINAVYT---KQSYEQIIELVDFCIENK--IDRFSVANYSEVTGYT......................................... 299
7 -16.8005tgs_A mol:protein length:263 7-carboxy-7-deazaguanine synthase  ali model follow..  17  91.....HVTISGGNPALLKQ-LDAFIELLKENNIRAALETQGTVY----QDWFTLIDDLTISPKPPSSKMVTNF-----QKLDHILTSLQENDRQHAVSLKVVIFNDEDLEFAKTVHKRYPGIPFYLQ....................................................... 202
8 -16.7003rf9_A mol:protein length:404 Ribosomal RNA large subunit methyltransferase N  ali model follow..  15  172.....NVVMMGGEPLLNLNNVVPAMEIMLDDF-RVTLSTSGVVP--ALDKLGDMIDVALISLHAPNDEIRDEIVPINKKYNIETFEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTP----KINLIPWNPFPGAPYG--------------RSSNSRIDRFSKVLMSYGFTTIV.. 343
9 -16.6001tv7_A mol:protein length:340 Molybdenum cofactor biosynthesis protein A  ali model follow..  15  70......IRITGGEPLMRRDLDVLIAKLNQIDGIDIGLTTNGLLLKKHGQKLYDALRRINVSLDAIDDTLFQSINNRNITTILEQIDYATSIGLNVKVNVVIQKGINDDQ--IIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKV-LTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFG. 251
10 -15.5006c8v_A mol:protein length:394 Coenzyme PQQ synthesis protein E  ali model follow..  14  72......VHLSGGEPTARPDIV-EITAKCAELGLYSNLITSGVGGALAKLDALYDVGLVQLSVQGVDAANAEKIGGLKNPQKMQFAARVTELGLPLTLNSVI---HRGNIHEVPGFIDLAVKLG--AKRLEVAHTQYYGWAY----------VNRAALMPDKSQVDESIRIVEAA........ 227
11 -14.4006b4c_A mol:protein length:298 Viperin  ali model follow..  14  58......INFAGGEPFLYPKFLGEMIDFCKETLESVSIVTNGLVKEQFLQKHGRNIDILAVSCDSFNEATNIKIGGDNVQKLYEIGSWCQKYDIKFKLNTVVNK--FNHLEDMNDHLNALQPF--RWKCFQVLIVTGENDSD......................................... 194
12 -12.7005vsl_A mol:protein length:318 Radical S-adenosyl methionine domain-containing protein 2  ali model follow..  15  77......INFSGGEPFLQDRGLGKLVRFCKEELASVSIVSNGLIRERWFKDYGEYLDILAISCDSFDEQVNALIGGQGKKNHVENLQKLRRRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGEDALRE...................................... 222
13 -11.9005wgg_A mol:protein length:453 Radical SAM domain protein  ali model follow..  14  152......IDFFGGEPMMNFDVVKGIIEYARQKNFRFTLTTNGLLLNDENIKYINENMQLSID-KEVNDRMRIRIDGSGCDDILPKFKYVAESRNQDNYYVRG----TFTRENMDFSNDVLHLADEGFRQISVEPVVAAKDSGYDLREEDLPRLFEEYEKLAYEYVKRRKE............. 321
14 -11.2002a5h_A mol:protein length:416 L-lysine 2,3-aminomutase  ali model follow..  17  166......VLLSGGDALVSDETLEYIIAKLREIPHVEIVRIGSRTPVVLPQRITPELVNMLKKYHPVWLNTHFNHPNEITEESTRACQLLADAGVPLGNQSVLLRGVNDCVHVMKELVNKLVKIR-------VRPYY............................................... 288
15 -10.5004k36_A mol:protein length:392 Anaerobic sulfatase-maturating enzyme  ali model follow..  11  61......FAFQGGEPTLAGLEFFEKLMELQRKKIYNSLQTNGTLIDESWAKFLSENKFLVMD-KEIHNLNRKDCCGLDTSKVERAAELFKKYKVEFNILCVVT---SNTARHVNKVYKYFKEKD--FKFLQFIN................................................. 193
16 -9.3005zl9_A mol:protein length:618 Chitinase AB  ali model follow..  14  248..SIGGWTLSDGDKVKRDRFVGSVKEFLQTWKFFDGVD----------------IDWEFPGGKGANPNLGSPQDGETYVLLMKELRALDQLSVETGRKYELTSAISAGKDKIDKFYSFVNVAQNSMDHIFLMSYDFYGAFDLKNLGHQTALNAPAWKPDTAYTTVNGVNALLAQGVKIVVG. 419
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.